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Overview

ID MAG03173
Name PYH2_bin.10
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAKOQB01
Species
Assembly information
Completeness (%) 95.72
Contamination (%) 1.99
GC content (%) 64.0
N50 (bp) 15,046
Genome size (bp) 4,005,202

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3957

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1014123_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1034.0
PYH2_k127_1014123_1 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 488.0
PYH2_k127_1014123_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 306.0
PYH2_k127_1014123_3 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000004079 185.0
PYH2_k127_1014123_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000009045 179.0
PYH2_k127_1014123_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000003827 120.0
PYH2_k127_1014123_6 Copper binding periplasmic protein CusF - - - 0.0000000000000004969 83.0
PYH2_k127_1029869_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 474.0
PYH2_k127_1029869_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 400.0
PYH2_k127_1029869_2 Short-chain dehydrogenase reductase sdr K22185 - 1.1.1.175 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
PYH2_k127_1029869_3 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000001606 257.0
PYH2_k127_1029869_4 Biotin-requiring enzyme - - - 0.0000000000000000002293 91.0
PYH2_k127_1090102_0 Thioredoxin - - - 0.000000000000000000000000000000000000000000143 170.0
PYH2_k127_1090102_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000001238 146.0
PYH2_k127_1090102_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000002364 81.0
PYH2_k127_1090102_3 domain protein - - - 0.000877 44.0
PYH2_k127_1102890_0 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 323.0
PYH2_k127_1102890_1 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000001496 197.0
PYH2_k127_1102890_2 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000685 87.0
PYH2_k127_1102890_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000001996 56.0
PYH2_k127_1121711_0 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 403.0
PYH2_k127_1121711_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 334.0
PYH2_k127_1121711_10 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000005942 130.0
PYH2_k127_1121711_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000002377 97.0
PYH2_k127_1121711_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 331.0
PYH2_k127_1121711_3 Biopolymer transport K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000537 274.0
PYH2_k127_1121711_4 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001246 265.0
PYH2_k127_1121711_5 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001918 268.0
PYH2_k127_1121711_6 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000204 224.0
PYH2_k127_1121711_7 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000001337 202.0
PYH2_k127_1121711_8 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000002631 195.0
PYH2_k127_1121711_9 Biopolymer transport K03559 - - 0.000000000000000000000000000000000009332 150.0
PYH2_k127_1125004_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 387.0
PYH2_k127_1125004_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000003189 133.0
PYH2_k127_1141104_0 PFAM type II secretion system K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 434.0
PYH2_k127_1141104_1 PFAM type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000004887 237.0
PYH2_k127_1141104_10 - - - - 0.00000000002029 73.0
PYH2_k127_1141104_2 PFAM Fimbrial assembly family protein K02461 - - 0.00000000000000000000000000000000000000000000000000000000000007703 226.0
PYH2_k127_1141104_3 secretory pathway K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000002604 200.0
PYH2_k127_1141104_4 PFAM type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000002671 217.0
PYH2_k127_1141104_5 type II secretion system protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001141 202.0
PYH2_k127_1141104_6 TIGRFAM general secretion pathway protein H K02457 - - 0.000000000000000000000000000000000000165 146.0
PYH2_k127_1141104_7 Pfam:N_methyl_2 K02459 - - 0.0000000000000000000000000000000002889 140.0
PYH2_k127_1141104_8 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000000000000000000000000001539 126.0
PYH2_k127_1141104_9 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000000000000001747 119.0
PYH2_k127_114972_0 Formyl transferase K19640 - - 2.741e-211 677.0
PYH2_k127_114972_1 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 536.0
PYH2_k127_114972_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 533.0
PYH2_k127_114972_3 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000005626 231.0
PYH2_k127_114972_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000007813 176.0
PYH2_k127_114972_5 transcriptional regulators K03892 - - 0.0000000000000000000000000000000000236 138.0
PYH2_k127_114972_6 - - - - 0.000000000000000000000000000000000416 147.0
PYH2_k127_114972_7 - - - - 0.0000000000000000000008431 102.0
PYH2_k127_114972_8 selenide, water dikinase activity K01008 - 2.7.9.3 0.0002177 44.0
PYH2_k127_11823_0 ABC-type dipeptide transport system, periplasmic component K02035,K12368 - - 7.225e-263 813.0
PYH2_k127_11823_1 ABC-type dipeptide oligopeptide nickel transport K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 567.0
PYH2_k127_11823_2 ABC-type dipeptide oligopeptide nickel transport system, permease component K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
PYH2_k127_11823_3 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 424.0
PYH2_k127_1202414_0 FAD dependent oxidoreductase central domain - - - 0.0 1323.0
PYH2_k127_1202414_1 Peptidase M61 - - - 2.349e-209 666.0
PYH2_k127_1202414_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 437.0
PYH2_k127_1202414_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 381.0
PYH2_k127_1202414_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000005447 180.0
PYH2_k127_1202414_5 - - - - 0.00000000000009416 76.0
PYH2_k127_1202414_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000001198 65.0
PYH2_k127_1203596_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.784e-304 937.0
PYH2_k127_1203596_1 PrkA AAA domain K07180 - - 2.805e-279 872.0
PYH2_k127_1203596_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 410.0
PYH2_k127_1203596_11 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 408.0
PYH2_k127_1203596_12 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 409.0
PYH2_k127_1203596_13 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 389.0
PYH2_k127_1203596_14 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 356.0
PYH2_k127_1203596_15 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004874 253.0
PYH2_k127_1203596_16 peptidase, M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002825 263.0
PYH2_k127_1203596_17 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000001925 239.0
PYH2_k127_1203596_18 cytochrome C oxidase K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000003731 241.0
PYH2_k127_1203596_19 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000009567 252.0
PYH2_k127_1203596_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.863e-256 810.0
PYH2_k127_1203596_20 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000006978 218.0
PYH2_k127_1203596_21 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000008575 218.0
PYH2_k127_1203596_22 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000732 196.0
PYH2_k127_1203596_23 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000000008172 192.0
PYH2_k127_1203596_24 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000002485 191.0
PYH2_k127_1203596_25 Cell division ATP-binding protein ftsE K09812 - - 0.00000000000000000000000000000000000000000000000001791 188.0
PYH2_k127_1203596_26 SURF1-like protein - - - 0.00000000000000000000000000000000000000000000312 176.0
PYH2_k127_1203596_27 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000001139 172.0
PYH2_k127_1203596_28 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000007221 142.0
PYH2_k127_1203596_29 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000004182 138.0
PYH2_k127_1203596_3 SpoVR family K06415 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 556.0
PYH2_k127_1203596_30 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000001477 136.0
PYH2_k127_1203596_31 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000003084 132.0
PYH2_k127_1203596_32 Conserved hypothetical protein 95 - - - 0.00000000000000000000092 109.0
PYH2_k127_1203596_33 Integral membrane protein (DUF2244) - - - 0.000000000000000000001752 99.0
PYH2_k127_1203596_34 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000005576 85.0
PYH2_k127_1203596_35 Protein of unknown function (DUF2970) - - - 0.000000000000001848 84.0
PYH2_k127_1203596_36 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000007934 83.0
PYH2_k127_1203596_37 Protein of unknown function (DUF2909) - - - 0.0000000000007326 72.0
PYH2_k127_1203596_38 - - - - 0.000005545 57.0
PYH2_k127_1203596_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 529.0
PYH2_k127_1203596_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 512.0
PYH2_k127_1203596_6 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 461.0
PYH2_k127_1203596_7 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
PYH2_k127_1203596_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
PYH2_k127_1203596_9 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 419.0
PYH2_k127_1254217_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.017e-227 719.0
PYH2_k127_1254217_1 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 541.0
PYH2_k127_1254217_10 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 335.0
PYH2_k127_1254217_11 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 333.0
PYH2_k127_1254217_12 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
PYH2_k127_1254217_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 309.0
PYH2_k127_1254217_14 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 300.0
PYH2_k127_1254217_15 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 301.0
PYH2_k127_1254217_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007045 258.0
PYH2_k127_1254217_17 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000002656 231.0
PYH2_k127_1254217_18 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000009296 218.0
PYH2_k127_1254217_19 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
PYH2_k127_1254217_2 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 517.0
PYH2_k127_1254217_20 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000005563 188.0
PYH2_k127_1254217_21 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000001057 190.0
PYH2_k127_1254217_22 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000003089 177.0
PYH2_k127_1254217_23 Chalcone isomerase-like - - - 0.000000000000000000000000000000000002428 147.0
PYH2_k127_1254217_24 cell division protein - - - 0.0000000000000000000000000003017 126.0
PYH2_k127_1254217_25 - - - - 0.000000000000000000000000004372 119.0
PYH2_k127_1254217_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 501.0
PYH2_k127_1254217_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 476.0
PYH2_k127_1254217_5 Binding-protein-dependent transport system inner membrane component K10009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 425.0
PYH2_k127_1254217_6 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 398.0
PYH2_k127_1254217_7 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 374.0
PYH2_k127_1254217_8 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 358.0
PYH2_k127_1254217_9 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
PYH2_k127_1255611_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.134e-294 922.0
PYH2_k127_1255611_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.481e-199 630.0
PYH2_k127_1255611_10 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000003537 77.0
PYH2_k127_1255611_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.499e-195 619.0
PYH2_k127_1255611_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 458.0
PYH2_k127_1255611_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 432.0
PYH2_k127_1255611_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 392.0
PYH2_k127_1255611_6 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 378.0
PYH2_k127_1255611_7 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001116 261.0
PYH2_k127_1255611_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000001109 243.0
PYH2_k127_1255611_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000003752 144.0
PYH2_k127_1290757_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1047.0
PYH2_k127_1290757_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
PYH2_k127_1290757_2 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008209 231.0
PYH2_k127_1290757_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000005458 225.0
PYH2_k127_1290757_4 COGs COG1569 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000000000000000000009426 183.0
PYH2_k127_1290757_5 PFAM SpoVT AbrB - - - 0.00000000000000000000000000001788 119.0
PYH2_k127_1290757_6 Transposase DDE domain - - - 0.000000000002566 67.0
PYH2_k127_1290757_7 ADAMTS-like protein 5 K15686 GO:0001527,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0008201,GO:0031012,GO:0043167,GO:0043168,GO:0044420,GO:0044421,GO:0097367,GO:0099080,GO:0099081,GO:0099512,GO:1901681 2.3.2.27 0.0008077 46.0
PYH2_k127_1312259_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1105.0
PYH2_k127_1312259_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.757e-316 978.0
PYH2_k127_1312259_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 323.0
PYH2_k127_1312259_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 309.0
PYH2_k127_1312259_12 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 282.0
PYH2_k127_1312259_13 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
PYH2_k127_1312259_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001459 277.0
PYH2_k127_1312259_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 269.0
PYH2_k127_1312259_16 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001397 244.0
PYH2_k127_1312259_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003634 201.0
PYH2_k127_1312259_18 - - - - 0.00000000000000000000000000000000000000000000000002989 187.0
PYH2_k127_1312259_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000004621 155.0
PYH2_k127_1312259_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.056e-267 830.0
PYH2_k127_1312259_20 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000003821 151.0
PYH2_k127_1312259_21 Twin-arginine translocation pathway signal protein - - - 0.00000000000000000000000000000000003994 141.0
PYH2_k127_1312259_22 Protein of unknown function (DUF541) - - - 0.00000000000000000000000002547 117.0
PYH2_k127_1312259_23 RDD family protein 2 - - - 0.0000000000000000000000002217 111.0
PYH2_k127_1312259_24 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000001447 107.0
PYH2_k127_1312259_25 Protein of unknown function (DUF3106) - - - 0.0000000000000000000002547 103.0
PYH2_k127_1312259_26 Protein of unknown function (DUF3619) - - - 0.000000000000000002107 91.0
PYH2_k127_1312259_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.361e-255 790.0
PYH2_k127_1312259_4 GMC oxidoreductase - - - 4.696e-223 710.0
PYH2_k127_1312259_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 565.0
PYH2_k127_1312259_6 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 470.0
PYH2_k127_1312259_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 396.0
PYH2_k127_1312259_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 324.0
PYH2_k127_1314908_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 426.0
PYH2_k127_1314908_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
PYH2_k127_1314908_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 344.0
PYH2_k127_1314908_3 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002117 243.0
PYH2_k127_1359411_0 ABC-type Fe3 transport system permease component K02011 - - 6.004e-254 795.0
PYH2_k127_1359411_1 Branched-chain amino acid transport system / permease component K01997,K01998 - - 2.773e-212 677.0
PYH2_k127_1359411_10 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
PYH2_k127_1359411_11 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007573 260.0
PYH2_k127_1359411_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 258.0
PYH2_k127_1359411_13 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001538 231.0
PYH2_k127_1359411_14 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000002383 198.0
PYH2_k127_1359411_15 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000002487 179.0
PYH2_k127_1359411_16 PFAM acyl-coA-binding protein, ACBP - - - 0.0000000000000000000000000000000008315 132.0
PYH2_k127_1359411_17 CHRD domain - - - 0.00000000000000000000000000005202 124.0
PYH2_k127_1359411_18 - - - - 0.000000000000000000000000003175 115.0
PYH2_k127_1359411_19 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000005611 88.0
PYH2_k127_1359411_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 9.213e-203 639.0
PYH2_k127_1359411_3 ABC-type Fe3 transport system, periplasmic component - - - 8.571e-196 621.0
PYH2_k127_1359411_4 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 602.0
PYH2_k127_1359411_5 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 591.0
PYH2_k127_1359411_6 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 462.0
PYH2_k127_1359411_7 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 402.0
PYH2_k127_1359411_8 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 325.0
PYH2_k127_1359411_9 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
PYH2_k127_1363743_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.308e-289 903.0
PYH2_k127_1363743_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.809e-239 745.0
PYH2_k127_1363743_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 463.0
PYH2_k127_1363743_3 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 402.0
PYH2_k127_1363743_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 402.0
PYH2_k127_1363743_5 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
PYH2_k127_1363743_6 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
PYH2_k127_1363743_7 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000168 184.0
PYH2_k127_1363743_8 Ribosomal protein L31 K02909 - - 0.0000000000000000000000000000004484 131.0
PYH2_k127_1363743_9 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000002601 81.0
PYH2_k127_1446550_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.615e-266 829.0
PYH2_k127_1446550_1 Cytochrome b(N-terminal)/b6/petB - - - 1.375e-227 722.0
PYH2_k127_1446550_10 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000006232 179.0
PYH2_k127_1446550_11 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000003074 126.0
PYH2_k127_1446550_12 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.000000000000000000005086 93.0
PYH2_k127_1446550_13 PEP-CTERM motif - - - 0.00000000000000000003745 98.0
PYH2_k127_1446550_14 - - - - 0.0000000002066 65.0
PYH2_k127_1446550_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 518.0
PYH2_k127_1446550_3 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 327.0
PYH2_k127_1446550_4 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 291.0
PYH2_k127_1446550_5 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 295.0
PYH2_k127_1446550_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003613 286.0
PYH2_k127_1446550_7 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000002137 229.0
PYH2_k127_1446550_8 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000001919 227.0
PYH2_k127_1446550_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000001323 184.0
PYH2_k127_1476490_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 431.0
PYH2_k127_1476490_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 346.0
PYH2_k127_1476490_2 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 301.0
PYH2_k127_1476490_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 294.0
PYH2_k127_1476490_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000009008 154.0
PYH2_k127_1476490_6 OsmC-like protein - - - 0.0002036 47.0
PYH2_k127_1481026_0 cytosine deaminase K01485 - 3.5.4.1 4.082e-225 702.0
PYH2_k127_1481026_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 512.0
PYH2_k127_1481026_10 - - - - 0.00000000000000000000000000000000000000000000000000000159 200.0
PYH2_k127_1481026_11 BON domain - - - 0.00000000000000000000000000000000000000003528 163.0
PYH2_k127_1481026_12 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000004173 160.0
PYH2_k127_1481026_13 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000007066 126.0
PYH2_k127_1481026_14 Type II secretion system protein B K02451 - - 0.00000000000000002706 86.0
PYH2_k127_1481026_15 Protein of unknown function (DUF3144) - - - 0.000000003287 64.0
PYH2_k127_1481026_16 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00007828 46.0
PYH2_k127_1481026_2 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 433.0
PYH2_k127_1481026_3 MFS transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 407.0
PYH2_k127_1481026_4 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 377.0
PYH2_k127_1481026_5 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 377.0
PYH2_k127_1481026_6 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 361.0
PYH2_k127_1481026_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 327.0
PYH2_k127_1481026_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 299.0
PYH2_k127_1481026_9 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000003337 235.0
PYH2_k127_1503388_0 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 1.432e-216 681.0
PYH2_k127_1503388_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 410.0
PYH2_k127_1503388_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 379.0
PYH2_k127_1503388_3 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 368.0
PYH2_k127_1503388_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 300.0
PYH2_k127_1503388_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002048 276.0
PYH2_k127_1503388_6 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000232 265.0
PYH2_k127_1503388_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000001437 105.0
PYH2_k127_1503388_8 - - - - 0.0000000003204 60.0
PYH2_k127_1537819_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 489.0
PYH2_k127_1537819_1 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 410.0
PYH2_k127_1537819_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 397.0
PYH2_k127_1537819_3 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 317.0
PYH2_k127_1537819_4 - - - - 0.00000000000000000000000000000005172 131.0
PYH2_k127_1642822_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 1.528e-281 879.0
PYH2_k127_1642822_1 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000009552 182.0
PYH2_k127_1663845_0 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003584 280.0
PYH2_k127_1663845_1 - - - - 0.000000000000000000000001889 116.0
PYH2_k127_1663845_2 - - - - 0.00005115 51.0
PYH2_k127_1667524_0 Participates in both transcription termination and antitermination K02600 - - 1.639e-212 671.0
PYH2_k127_1667524_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 362.0
PYH2_k127_1667524_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000005739 238.0
PYH2_k127_1667524_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000009647 167.0
PYH2_k127_1694983_0 ABC transporter transmembrane region K06147 - - 3.191e-263 831.0
PYH2_k127_1694983_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 584.0
PYH2_k127_1694983_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 279.0
PYH2_k127_1694983_11 KorB domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000003973 243.0
PYH2_k127_1694983_12 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000008614 198.0
PYH2_k127_1694983_13 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000008556 181.0
PYH2_k127_1694983_14 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000000007649 176.0
PYH2_k127_1694983_15 - - - - 0.00000000000000000000000000000000000000009384 160.0
PYH2_k127_1694983_16 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000005788 146.0
PYH2_k127_1694983_17 - - - - 0.00000000000000000000000000001502 127.0
PYH2_k127_1694983_18 Oxidoreductase activity. It is involved in the biological process described with metabolic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000003874 53.0
PYH2_k127_1694983_19 Fumarase C C-terminus K01744 - 4.3.1.1 0.00001574 49.0
PYH2_k127_1694983_2 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 585.0
PYH2_k127_1694983_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 547.0
PYH2_k127_1694983_4 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 547.0
PYH2_k127_1694983_5 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 448.0
PYH2_k127_1694983_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 436.0
PYH2_k127_1694983_7 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 421.0
PYH2_k127_1694983_8 acid transport system permease K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 384.0
PYH2_k127_1694983_9 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 353.0
PYH2_k127_1697521_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.076e-285 895.0
PYH2_k127_1697521_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.213e-272 849.0
PYH2_k127_1697521_10 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 328.0
PYH2_k127_1697521_11 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 299.0
PYH2_k127_1697521_12 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 299.0
PYH2_k127_1697521_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001667 273.0
PYH2_k127_1697521_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000008694 250.0
PYH2_k127_1697521_15 - - - - 0.000000000000000000000000000000000000007209 151.0
PYH2_k127_1697521_16 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000001883 117.0
PYH2_k127_1697521_2 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.872e-259 806.0
PYH2_k127_1697521_3 nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 3.098e-211 671.0
PYH2_k127_1697521_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 554.0
PYH2_k127_1697521_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 504.0
PYH2_k127_1697521_6 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
PYH2_k127_1697521_7 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 415.0
PYH2_k127_1697521_8 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 413.0
PYH2_k127_1697521_9 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 337.0
PYH2_k127_1719272_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 417.0
PYH2_k127_1719272_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 365.0
PYH2_k127_1719272_2 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 363.0
PYH2_k127_1719272_3 Two component transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 299.0
PYH2_k127_1719272_4 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000007181 194.0
PYH2_k127_1719272_5 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000002704 126.0
PYH2_k127_1719272_6 - - - - 0.0000000000000000000000000001354 129.0
PYH2_k127_1719272_7 Phospholipid methyltransferase - - - 0.000000000000004369 81.0
PYH2_k127_1719272_8 Heavy-metal resistance - - - 0.0000000000000625 81.0
PYH2_k127_172725_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1728.0
PYH2_k127_172725_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 582.0
PYH2_k127_172725_2 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 497.0
PYH2_k127_172725_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 427.0
PYH2_k127_172725_4 gluconokinase activity - - - 0.000000000000000000000004702 106.0
PYH2_k127_172725_5 Major facilitator superfamily K05820 - - 0.0000000000000000001465 99.0
PYH2_k127_172725_6 Domain of unknown function (DUF1127) - - - 0.0003703 43.0
PYH2_k127_172725_7 PFAM Integrase catalytic region K07497 - - 0.0005996 51.0
PYH2_k127_1735233_0 helicase superfamily c-terminal domain K03724 - - 0.0 1059.0
PYH2_k127_1735233_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 1.409e-229 722.0
PYH2_k127_1735233_2 B12 binding domain - - - 2.035e-207 660.0
PYH2_k127_1735233_3 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 445.0
PYH2_k127_1735233_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 424.0
PYH2_k127_1735233_5 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 330.0
PYH2_k127_1735233_6 SWIB/MDM2 domain K03169 - 5.99.1.2 0.000000000000000000000000000000000001808 143.0
PYH2_k127_1735233_7 - - - - 0.000000000000000000000000001979 114.0
PYH2_k127_1735233_8 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000007193 83.0
PYH2_k127_1745294_0 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 597.0
PYH2_k127_1745294_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
PYH2_k127_1745294_2 ornithine cyclodeaminase K01750 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 4.3.1.12 0.00000000000000000000000000000000000000000000000000001674 193.0
PYH2_k127_1745294_3 PFAM cytochrome c - - - 0.0000000003583 70.0
PYH2_k127_1749657_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002182 265.0
PYH2_k127_1749657_1 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
PYH2_k127_1749657_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000005113 199.0
PYH2_k127_1749657_3 DNA-binding - - - 0.00000000000000000000000000000000000000000000000000001114 195.0
PYH2_k127_1749657_4 - - - - 0.00000000000000000000000000000000000003275 151.0
PYH2_k127_1749657_5 helicase activity K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.0000000000000000000001674 100.0
PYH2_k127_1749657_6 Dienelactone hydrolase family - - - 0.000000000002988 70.0
PYH2_k127_1755943_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 6.085e-267 844.0
PYH2_k127_1755943_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 516.0
PYH2_k127_1755943_10 TonB C terminal K03646 - - 0.00000000000000000000002835 111.0
PYH2_k127_1755943_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 463.0
PYH2_k127_1755943_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 394.0
PYH2_k127_1755943_4 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 304.0
PYH2_k127_1755943_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
PYH2_k127_1755943_6 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000001192 202.0
PYH2_k127_1755943_7 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000001491 154.0
PYH2_k127_1755943_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000003575 151.0
PYH2_k127_1755943_9 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000009432 144.0
PYH2_k127_1771398_0 Domain of Unknown Function (DUF748) - - - 3.418e-240 784.0
PYH2_k127_1771398_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 335.0
PYH2_k127_1771398_2 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000008738 266.0
PYH2_k127_1771398_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000001646 261.0
PYH2_k127_1771398_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000003203 198.0
PYH2_k127_1771398_5 - - - - 0.0000000000000000000000000000000000000000001618 174.0
PYH2_k127_1809823_0 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 486.0
PYH2_k127_1809823_1 abc transporter atp-binding protein K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 304.0
PYH2_k127_1809823_2 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
PYH2_k127_1852014_0 SurA N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 305.0
PYH2_k127_1852014_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009728 281.0
PYH2_k127_1852014_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
PYH2_k127_1852014_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000391 150.0
PYH2_k127_1852014_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000007656 96.0
PYH2_k127_185812_0 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 427.0
PYH2_k127_185812_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
PYH2_k127_185812_2 - - - - 0.000000000000000000000000000000000000000000000000000005799 195.0
PYH2_k127_185812_3 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000007192 150.0
PYH2_k127_185812_4 transcription regulator containing HTH domain K18831 - - 0.0000000000000000000000371 104.0
PYH2_k127_185812_5 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000002438 74.0
PYH2_k127_1867608_0 FAD linked oxidase domain protein - - - 0.0 2018.0
PYH2_k127_1867608_1 - - - - 0.00000000000000000000000000000000000009027 151.0
PYH2_k127_1867608_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000001108 103.0
PYH2_k127_1868496_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1046.0
PYH2_k127_1868496_1 prolyl oligopeptidase K01322 - 3.4.21.26 2.489e-219 700.0
PYH2_k127_1868496_10 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000002247 244.0
PYH2_k127_1868496_11 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000002576 226.0
PYH2_k127_1868496_12 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000002939 226.0
PYH2_k127_1868496_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000004238 182.0
PYH2_k127_1868496_14 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000005244 141.0
PYH2_k127_1868496_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000004554 125.0
PYH2_k127_1868496_16 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000069 103.0
PYH2_k127_1868496_18 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000001887 58.0
PYH2_k127_1868496_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 587.0
PYH2_k127_1868496_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 590.0
PYH2_k127_1868496_4 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 523.0
PYH2_k127_1868496_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 476.0
PYH2_k127_1868496_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 464.0
PYH2_k127_1868496_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 409.0
PYH2_k127_1868496_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH2_k127_1868496_9 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 285.0
PYH2_k127_1875240_0 fad dependent oxidoreductase K07137 - - 8.292e-287 891.0
PYH2_k127_1875240_1 4Fe-4S dicluster domain - - - 6.406e-275 856.0
PYH2_k127_1875240_10 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000762 192.0
PYH2_k127_1875240_11 Branched-chain amino acid permease - - - 0.0000000000000000000000000000000000000000000000000005268 207.0
PYH2_k127_1875240_12 - - - - 0.00000000000000000000000000000000001617 143.0
PYH2_k127_1875240_13 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000004259 136.0
PYH2_k127_1875240_14 SnoaL-like domain - - - 0.000000000000000000000000000000501 127.0
PYH2_k127_1875240_15 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000209 117.0
PYH2_k127_1875240_16 Methyltransferase domain - - - 0.00000000000000000000002047 103.0
PYH2_k127_1875240_17 Zinc-finger domain - - - 0.00000000000000000000002136 103.0
PYH2_k127_1875240_18 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000002039 103.0
PYH2_k127_1875240_19 - - - - 0.0000000000000000000004135 103.0
PYH2_k127_1875240_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 578.0
PYH2_k127_1875240_20 FAD linked oxidases, C-terminal domain K18930 - - 0.00000000002627 67.0
PYH2_k127_1875240_21 Lipase class 3 family protein - - - 0.0004385 53.0
PYH2_k127_1875240_3 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 547.0
PYH2_k127_1875240_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 499.0
PYH2_k127_1875240_5 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 484.0
PYH2_k127_1875240_6 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 398.0
PYH2_k127_1875240_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 364.0
PYH2_k127_1875240_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
PYH2_k127_1875240_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
PYH2_k127_1901115_0 SMART Elongator protein 3 MiaB NifB - - - 4.549e-201 635.0
PYH2_k127_1901115_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 299.0
PYH2_k127_1901115_2 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000002966 196.0
PYH2_k127_1901115_3 Methyltransferase domain - - - 0.000000000000000000000000000006309 123.0
PYH2_k127_1910140_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 472.0
PYH2_k127_1910140_1 PFAM Transcriptional - - - 0.00000000000000000000000000000000000000000000000152 184.0
PYH2_k127_1923823_0 Homeodomain-like domain K07497 - - 0.0000000000000000000000000000000000000005729 149.0
PYH2_k127_1923823_1 Elements of external origin K07497 - - 0.00000000000000000000000000000000000114 145.0
PYH2_k127_1923823_2 Putative transposase - - - 0.0000000000001542 72.0
PYH2_k127_1923823_3 - - - - 0.00000000001986 69.0
PYH2_k127_1923823_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000005473 53.0
PYH2_k127_1926625_0 Dehydratase family K01690 - 4.2.1.12 7.527e-275 856.0
PYH2_k127_1926625_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.741e-239 763.0
PYH2_k127_1926625_10 Alpha-amylase K01176 GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005975,GO:0008150,GO:0008152,GO:0016160,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704 3.2.1.1 0.0000000000000000000000000000000000005426 146.0
PYH2_k127_1926625_11 DDE superfamily endonuclease K07494 - - 0.000000000594 62.0
PYH2_k127_1926625_12 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00003292 49.0
PYH2_k127_1926625_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 2.684e-215 686.0
PYH2_k127_1926625_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.534e-204 649.0
PYH2_k127_1926625_4 Maltoporin (phage lambda and maltose receptor) K02024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 407.0
PYH2_k127_1926625_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 336.0
PYH2_k127_1926625_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006689 264.0
PYH2_k127_1926625_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000009525 222.0
PYH2_k127_1926625_8 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000002345 223.0
PYH2_k127_1926625_9 Bacterial pullanase-associated domain - - - 0.0000000000000000000000000000000000000000000000000000001854 207.0
PYH2_k127_1938922_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.844e-238 748.0
PYH2_k127_1938922_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.036e-213 680.0
PYH2_k127_1938922_10 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006331 278.0
PYH2_k127_1938922_11 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001349 251.0
PYH2_k127_1938922_12 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000000000000000004854 169.0
PYH2_k127_1938922_13 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000001495 152.0
PYH2_k127_1938922_14 Tautomerase enzyme - - - 0.0000000000000000000000000000000000004934 149.0
PYH2_k127_1938922_15 NAD-dependent DNA ligase - - - 0.00000000000000000000000000000000008993 141.0
PYH2_k127_1938922_16 Bacterial PH domain - - - 0.000000000000000000000000000001087 124.0
PYH2_k127_1938922_17 - - - - 0.000000000000000000000000000001788 125.0
PYH2_k127_1938922_18 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000003104 116.0
PYH2_k127_1938922_19 Activates fatty acids by binding to coenzyme A K20034 - 6.2.1.44 0.0000000000000000002832 89.0
PYH2_k127_1938922_2 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 605.0
PYH2_k127_1938922_20 - - - - 0.000000000001931 72.0
PYH2_k127_1938922_21 SnoaL-like domain - - - 0.00000000000888 71.0
PYH2_k127_1938922_3 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 525.0
PYH2_k127_1938922_4 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 503.0
PYH2_k127_1938922_5 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 419.0
PYH2_k127_1938922_6 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 373.0
PYH2_k127_1938922_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 391.0
PYH2_k127_1938922_9 Domain of unknown function (DUF3394) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002542 273.0
PYH2_k127_1943916_0 Domain of unknown function (DUF3362) - - - 2.096e-314 970.0
PYH2_k127_1943916_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 457.0
PYH2_k127_1943916_2 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 371.0
PYH2_k127_1943916_3 - - - - 0.00000000000000000000000000002446 134.0
PYH2_k127_1943916_4 SnoaL-like domain - - - 0.000000000000001501 79.0
PYH2_k127_1943916_5 Helix-turn-helix domain - - - 0.0000001086 55.0
PYH2_k127_1943916_6 endonuclease activity - - - 0.0002554 50.0
PYH2_k127_1948092_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 385.0
PYH2_k127_1948092_1 HIT domain - - - 0.00000000000000000000000000000000000000000000001176 180.0
PYH2_k127_1948092_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000002139 145.0
PYH2_k127_1948092_3 Sporulation domain protein - - - 0.000000000000004438 83.0
PYH2_k127_1948092_4 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0002916 46.0
PYH2_k127_195142_0 Neisseria PilC beta-propeller domain K02674 - - 2.139e-239 780.0
PYH2_k127_195142_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.529e-198 639.0
PYH2_k127_195142_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000009578 162.0
PYH2_k127_195142_11 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000002508 153.0
PYH2_k127_195142_12 Type II transport protein GspH K08084 - - 0.000000000000000000000000000000000001301 147.0
PYH2_k127_195142_13 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000000001836 135.0
PYH2_k127_195142_14 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.00000000000000000000000000007505 119.0
PYH2_k127_195142_15 type IV pilus modification protein PilV K02671 - - 0.0000000000000000002769 93.0
PYH2_k127_195142_16 pilus modification protein PilV K02671 - - 0.0000000000000000003228 94.0
PYH2_k127_195142_17 TonB family K03832 - - 0.000000000000000006597 91.0
PYH2_k127_195142_18 PilX N-terminal K02673 - - 0.00000000000000001158 93.0
PYH2_k127_195142_19 Type II transport protein GspH K08084 - - 0.000000000000009681 82.0
PYH2_k127_195142_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 511.0
PYH2_k127_195142_20 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000002118 80.0
PYH2_k127_195142_21 Pilus assembly protein K08084 - - 0.00000000000006637 79.0
PYH2_k127_195142_23 import inner membrane translocase, subunit Tim44 - - - 0.00005963 48.0
PYH2_k127_195142_3 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 537.0
PYH2_k127_195142_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 372.0
PYH2_k127_195142_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006668 253.0
PYH2_k127_195142_6 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000000004353 250.0
PYH2_k127_195142_7 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000003741 199.0
PYH2_k127_195142_8 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000001494 191.0
PYH2_k127_195142_9 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000001295 177.0
PYH2_k127_1958907_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 5.835e-240 750.0
PYH2_k127_1958907_1 DNA polymerase X family K02347 - - 5.953e-235 739.0
PYH2_k127_1958907_10 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000006014 140.0
PYH2_k127_1958907_11 response regulator - - - 0.0000000000000000000000002694 119.0
PYH2_k127_1958907_12 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000000000000000000000001249 118.0
PYH2_k127_1958907_13 - - - - 0.00000000000000000008763 90.0
PYH2_k127_1958907_14 Immunoglobulin - - - 0.00000000000002026 78.0
PYH2_k127_1958907_15 - - - - 0.0000000000792 72.0
PYH2_k127_1958907_2 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 449.0
PYH2_k127_1958907_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 435.0
PYH2_k127_1958907_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 347.0
PYH2_k127_1958907_5 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 286.0
PYH2_k127_1958907_6 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002891 243.0
PYH2_k127_1958907_7 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000000000002411 201.0
PYH2_k127_1958907_8 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000002827 201.0
PYH2_k127_1958907_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000001908 145.0
PYH2_k127_1963595_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 453.0
PYH2_k127_1963595_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 424.0
PYH2_k127_1963595_2 PFAM integrase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 325.0
PYH2_k127_1963595_3 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000007167 197.0
PYH2_k127_1963595_4 PFAM Transposase DDE domain - - - 0.00000000000000000022 89.0
PYH2_k127_1976447_0 orn lys arg decarboxylase K01584 - 4.1.1.19 0.0 1215.0
PYH2_k127_1976447_1 Multicopper oxidase - - - 1.588e-275 867.0
PYH2_k127_1976447_2 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 313.0
PYH2_k127_1976447_3 Histidine kinase K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000234 153.0
PYH2_k127_1976447_4 - - - - 0.0000000000000000000000000000000004461 138.0
PYH2_k127_1976447_5 PFAM Amidohydrolase - - - 0.00000000000004272 76.0
PYH2_k127_1976447_6 - - - - 0.00000000006109 64.0
PYH2_k127_1976447_7 general secretion pathway protein K02452 - - 0.000001383 59.0
PYH2_k127_1976447_9 PQQ-like domain - - - 0.0006157 48.0
PYH2_k127_1981965_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 363.0
PYH2_k127_1981965_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 338.0
PYH2_k127_1981965_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000001513 235.0
PYH2_k127_1981965_11 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000007121 175.0
PYH2_k127_1981965_12 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000006162 170.0
PYH2_k127_1981965_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004544 168.0
PYH2_k127_1981965_14 - - - - 0.0000000000000000000000000000000001499 135.0
PYH2_k127_1981965_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000001297 84.0
PYH2_k127_1981965_16 Domain of unknown function (DUF4936) - - - 0.00003797 55.0
PYH2_k127_1981965_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 322.0
PYH2_k127_1981965_3 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000907 274.0
PYH2_k127_1981965_4 Aminomethyltransferase folate-binding domain K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001548 263.0
PYH2_k127_1981965_5 proteins homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000008254 257.0
PYH2_k127_1981965_6 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000009834 254.0
PYH2_k127_1981965_7 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
PYH2_k127_1981965_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000007865 239.0
PYH2_k127_1981965_9 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000002475 232.0
PYH2_k127_1997029_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 413.0
PYH2_k127_1997029_1 molybdopterin cofactor binding - - - 0.000000001255 62.0
PYH2_k127_2001649_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1028.0
PYH2_k127_2001649_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1014.0
PYH2_k127_2001649_10 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 548.0
PYH2_k127_2001649_11 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 544.0
PYH2_k127_2001649_12 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
PYH2_k127_2001649_13 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 501.0
PYH2_k127_2001649_14 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 485.0
PYH2_k127_2001649_15 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 494.0
PYH2_k127_2001649_16 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 463.0
PYH2_k127_2001649_17 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 439.0
PYH2_k127_2001649_18 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 432.0
PYH2_k127_2001649_19 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 419.0
PYH2_k127_2001649_2 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1005.0
PYH2_k127_2001649_20 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 423.0
PYH2_k127_2001649_21 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 411.0
PYH2_k127_2001649_22 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 410.0
PYH2_k127_2001649_23 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 404.0
PYH2_k127_2001649_24 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 401.0
PYH2_k127_2001649_25 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 359.0
PYH2_k127_2001649_26 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 325.0
PYH2_k127_2001649_27 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 310.0
PYH2_k127_2001649_28 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 306.0
PYH2_k127_2001649_29 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009671 278.0
PYH2_k127_2001649_3 Molecular chaperone. Has ATPase activity K04079 - - 6.708e-299 928.0
PYH2_k127_2001649_30 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001295 270.0
PYH2_k127_2001649_31 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005567 278.0
PYH2_k127_2001649_32 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000005459 277.0
PYH2_k127_2001649_33 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 263.0
PYH2_k127_2001649_34 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007913 256.0
PYH2_k127_2001649_35 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 263.0
PYH2_k127_2001649_36 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001317 261.0
PYH2_k127_2001649_37 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
PYH2_k127_2001649_38 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000004445 254.0
PYH2_k127_2001649_39 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000007185 250.0
PYH2_k127_2001649_4 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 8.419e-280 870.0
PYH2_k127_2001649_40 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
PYH2_k127_2001649_41 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
PYH2_k127_2001649_42 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000142 223.0
PYH2_k127_2001649_43 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000002194 214.0
PYH2_k127_2001649_44 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000006816 203.0
PYH2_k127_2001649_45 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000003389 207.0
PYH2_k127_2001649_46 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000003607 193.0
PYH2_k127_2001649_47 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000004174 193.0
PYH2_k127_2001649_48 Haem-degrading K11477 - - 0.0000000000000000000000000000000000000000000000000004211 196.0
PYH2_k127_2001649_49 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000004835 209.0
PYH2_k127_2001649_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 8.697e-278 888.0
PYH2_k127_2001649_50 DUF218 domain - - - 0.00000000000000000000000000000000000000000000008902 178.0
PYH2_k127_2001649_51 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000002184 169.0
PYH2_k127_2001649_52 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000001236 159.0
PYH2_k127_2001649_53 Copper resistance protein D - - - 0.0000000000000000000000000000000000002367 148.0
PYH2_k127_2001649_54 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000004408 141.0
PYH2_k127_2001649_55 membrane - - - 0.000000000000000000000000000000000001548 147.0
PYH2_k127_2001649_56 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000002563 130.0
PYH2_k127_2001649_57 Protein conserved in bacteria K09705 - - 0.000000000000000000000000000003663 128.0
PYH2_k127_2001649_58 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000001249 119.0
PYH2_k127_2001649_59 AraC-like ligand binding domain - - - 0.0000000000000000000000000004455 116.0
PYH2_k127_2001649_6 PFAM AMP-dependent synthetase and ligase K00666 - - 1.77e-271 844.0
PYH2_k127_2001649_60 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000007302 116.0
PYH2_k127_2001649_61 Cytochrome c, class I - - - 0.0000000000000000000000003577 108.0
PYH2_k127_2001649_62 TM2 domain - - - 0.0000000000000000000008757 101.0
PYH2_k127_2001649_63 - - - - 0.00000000000000000001992 98.0
PYH2_k127_2001649_64 NlpC P60 family protein K19303 - - 0.000000001481 62.0
PYH2_k127_2001649_65 NlpC/P60 family - - - 0.0004972 46.0
PYH2_k127_2001649_7 Cysteine-rich domain - - - 1.302e-204 646.0
PYH2_k127_2001649_8 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 610.0
PYH2_k127_2001649_9 VWA domain containing CoxE-like protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 574.0
PYH2_k127_2042345_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 2.803e-295 915.0
PYH2_k127_2042345_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 574.0
PYH2_k127_2042345_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000001574 211.0
PYH2_k127_2042345_3 Protein of unknown function (DUF3579) - - - 0.00000000000000000000000000000000000002675 147.0
PYH2_k127_2042345_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000003579 105.0
PYH2_k127_2042345_5 Bacterial transcriptional activator domain - - - 0.000000000000003402 84.0
PYH2_k127_2042345_6 - - - - 0.00002959 54.0
PYH2_k127_2073868_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 435.0
PYH2_k127_2145161_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1053.0
PYH2_k127_2145161_1 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 484.0
PYH2_k127_2145161_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 493.0
PYH2_k127_2145161_3 PFAM Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 398.0
PYH2_k127_2145161_4 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 341.0
PYH2_k127_2145161_5 GON domain - - - 0.00000000000000000000000000000000000000002625 171.0
PYH2_k127_2145161_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000003502 101.0
PYH2_k127_2145161_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000004955 111.0
PYH2_k127_2145161_8 Glucose / Sorbosone dehydrogenase - - - 0.00000001536 67.0
PYH2_k127_2161161_0 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 444.0
PYH2_k127_2161161_1 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002234 259.0
PYH2_k127_2161161_2 nucleoside-diphosphate sugar epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
PYH2_k127_2161161_3 Thioredoxin domain - - - 0.0000000000000000004391 89.0
PYH2_k127_2191930_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.711e-207 651.0
PYH2_k127_2191930_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 573.0
PYH2_k127_2191930_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000099 72.0
PYH2_k127_2191930_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 552.0
PYH2_k127_2191930_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 541.0
PYH2_k127_2191930_4 3-5 exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
PYH2_k127_2191930_5 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 312.0
PYH2_k127_2191930_6 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 237.0
PYH2_k127_2191930_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001062 234.0
PYH2_k127_2191930_8 Tetratricopeptide repeat K02656 - - 0.00000000000000000000000000000000000000000000000000000000003396 220.0
PYH2_k127_2191930_9 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000002202 126.0
PYH2_k127_2197193_0 Belongs to the GcvT family K00302,K22086 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.3.1,1.5.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 336.0
PYH2_k127_2197193_1 Tryptophan-rich sensory protein K05770 - - 0.00000000000000000000000000000000000000000000000000000000002721 211.0
PYH2_k127_2197193_2 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000001589 121.0
PYH2_k127_2197193_3 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.000000000000000000007073 102.0
PYH2_k127_2197374_0 carbohydrate binding - - - 0.0 1507.0
PYH2_k127_2197374_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 616.0
PYH2_k127_2197374_10 - - - - 0.0000000000000000001478 94.0
PYH2_k127_2197374_11 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000001044 85.0
PYH2_k127_2197374_12 MerR HTH family regulatory protein K18997 - - 0.0000000000000002119 82.0
PYH2_k127_2197374_13 Belongs to the UPF0178 family K09768 - - 0.000000000001703 69.0
PYH2_k127_2197374_14 AI-2E family transporter - - - 0.0000006716 54.0
PYH2_k127_2197374_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000009598 50.0
PYH2_k127_2197374_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 539.0
PYH2_k127_2197374_3 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 336.0
PYH2_k127_2197374_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 334.0
PYH2_k127_2197374_5 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 305.0
PYH2_k127_2197374_6 Ferritin, Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 265.0
PYH2_k127_2197374_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000000001107 164.0
PYH2_k127_2197374_8 BON domain K04065 - - 0.000000000000000000000000000000002754 133.0
PYH2_k127_2197374_9 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000007346 127.0
PYH2_k127_2203789_0 Tricorn protease homolog K08676 - - 0.0 1099.0
PYH2_k127_2203789_1 Male sterility protein - - - 0.0 1018.0
PYH2_k127_2203789_10 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000292 181.0
PYH2_k127_2203789_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000002374 175.0
PYH2_k127_2203789_12 PFAM poly granule associated family protein - - - 0.0000000000000000000000000000000000002613 146.0
PYH2_k127_2203789_13 GtrA-like protein - - - 0.0000000000000000000000000000000002294 142.0
PYH2_k127_2203789_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 427.0
PYH2_k127_2203789_3 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH2_k127_2203789_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
PYH2_k127_2203789_5 Threonyl alanyl tRNA synthetase K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 324.0
PYH2_k127_2203789_6 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 327.0
PYH2_k127_2203789_7 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 314.0
PYH2_k127_2203789_8 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 311.0
PYH2_k127_2203789_9 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000007837 220.0
PYH2_k127_2205530_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.449e-250 782.0
PYH2_k127_2205530_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.4e-216 685.0
PYH2_k127_2205530_2 metal-dependent phosphoesterases (PHP family) K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
PYH2_k127_2205530_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 342.0
PYH2_k127_2205530_4 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
PYH2_k127_2205530_5 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 302.0
PYH2_k127_2205530_6 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
PYH2_k127_2205530_7 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001382 252.0
PYH2_k127_2205530_8 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000005634 191.0
PYH2_k127_2205530_9 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000202 176.0
PYH2_k127_2261124_0 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
PYH2_k127_2261124_1 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000001897 228.0
PYH2_k127_2261124_2 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000004612 156.0
PYH2_k127_2271181_0 Acyl-CoA dehydrogenase, middle domain - - - 6.789e-212 663.0
PYH2_k127_2271181_1 GYD domain - - - 0.000000000000000000000000000000525 124.0
PYH2_k127_2271181_2 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000007201 79.0
PYH2_k127_2271181_3 Protein of unknown function (DUF3617) - - - 0.00001019 53.0
PYH2_k127_2271181_4 Zinc-binding dehydrogenase - - - 0.00002396 52.0
PYH2_k127_2283210_0 oxidoreductase activity - - - 0.0 1079.0
PYH2_k127_2283210_1 Belongs to the malate synthase family K01638 - 2.3.3.9 4.484e-277 859.0
PYH2_k127_2283210_10 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 522.0
PYH2_k127_2283210_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 454.0
PYH2_k127_2283210_12 Di-haem cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 428.0
PYH2_k127_2283210_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 422.0
PYH2_k127_2283210_14 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 419.0
PYH2_k127_2283210_15 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 379.0
PYH2_k127_2283210_16 Chromate K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 306.0
PYH2_k127_2283210_17 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 312.0
PYH2_k127_2283210_18 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001135 282.0
PYH2_k127_2283210_19 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001311 276.0
PYH2_k127_2283210_2 Isocitrate lyase K01637 - 4.1.3.1 3.16e-250 779.0
PYH2_k127_2283210_20 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000006518 234.0
PYH2_k127_2283210_21 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000422 214.0
PYH2_k127_2283210_22 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000003858 190.0
PYH2_k127_2283210_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000002347 92.0
PYH2_k127_2283210_24 to GCN5-related N-acetyltransferase of Proteobacteria UniRef RepID Q46ZY6_RALEJ K03790 - 2.3.1.128 0.00000000000000005939 89.0
PYH2_k127_2283210_25 - - - - 0.00000000002781 64.0
PYH2_k127_2283210_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000001519 55.0
PYH2_k127_2283210_3 Selenium-binding protein K17285 - - 1.753e-245 765.0
PYH2_k127_2283210_4 SMART Tetratricopeptide domain protein - - - 8.829e-245 782.0
PYH2_k127_2283210_5 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 576.0
PYH2_k127_2283210_6 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 576.0
PYH2_k127_2283210_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 529.0
PYH2_k127_2283210_8 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 522.0
PYH2_k127_2283210_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 525.0
PYH2_k127_2302680_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.935e-245 769.0
PYH2_k127_2302680_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 529.0
PYH2_k127_2302680_10 Flagellar motor switch protein FliN K02417,K03225 - - 0.0000000000000000000000000000000000000000007433 167.0
PYH2_k127_2302680_11 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000006907 119.0
PYH2_k127_2302680_12 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000008288 117.0
PYH2_k127_2302680_13 membrane - - - 0.000000000000000000004646 101.0
PYH2_k127_2302680_14 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000006715 72.0
PYH2_k127_2302680_2 Flagellar motor switch K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 436.0
PYH2_k127_2302680_3 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 377.0
PYH2_k127_2302680_4 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 309.0
PYH2_k127_2302680_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 286.0
PYH2_k127_2302680_6 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000004061 234.0
PYH2_k127_2302680_7 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000000000000000000000006892 226.0
PYH2_k127_2302680_8 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000000008174 194.0
PYH2_k127_2302680_9 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000001964 191.0
PYH2_k127_2328969_0 TAP-like protein K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 541.0
PYH2_k127_2328969_1 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 499.0
PYH2_k127_2328969_10 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000009253 158.0
PYH2_k127_2328969_11 - - - - 0.0000005795 59.0
PYH2_k127_2328969_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 430.0
PYH2_k127_2328969_3 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 390.0
PYH2_k127_2328969_4 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 359.0
PYH2_k127_2328969_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 328.0
PYH2_k127_2328969_6 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 324.0
PYH2_k127_2328969_7 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001555 246.0
PYH2_k127_2328969_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
PYH2_k127_2328969_9 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000001426 229.0
PYH2_k127_2383625_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001388 283.0
PYH2_k127_2403623_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1461.0
PYH2_k127_2403623_1 PFAM FAD binding domain, FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 541.0
PYH2_k127_2403623_10 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000003242 143.0
PYH2_k127_2403623_11 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000001205 126.0
PYH2_k127_2403623_12 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000682 87.0
PYH2_k127_2403623_13 Phage integrase family - - - 0.00000000000000008147 81.0
PYH2_k127_2403623_14 Phage integrase family - - - 0.0000000000008189 74.0
PYH2_k127_2403623_15 Belongs to the 'phage' integrase family - - - 0.00000006821 57.0
PYH2_k127_2403623_16 Phage derived protein Gp49-like (DUF891) - - - 0.0000008603 53.0
PYH2_k127_2403623_17 Phage integrase family - - - 0.0000008969 51.0
PYH2_k127_2403623_18 Domain of unknown function (DUF4124) - - - 0.0001162 50.0
PYH2_k127_2403623_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 455.0
PYH2_k127_2403623_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
PYH2_k127_2403623_4 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 359.0
PYH2_k127_2403623_5 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 297.0
PYH2_k127_2403623_6 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
PYH2_k127_2403623_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
PYH2_k127_2403623_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000138 198.0
PYH2_k127_2403623_9 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000009801 161.0
PYH2_k127_2406237_0 DNA polymerase K02337 - 2.7.7.7 0.0 1155.0
PYH2_k127_2406237_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 561.0
PYH2_k127_2406237_2 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 517.0
PYH2_k127_2406237_3 - - - - 0.00000000000000000000000000000000001811 143.0
PYH2_k127_2406237_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000003057 140.0
PYH2_k127_2406237_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000007012 113.0
PYH2_k127_2406237_6 SNARE associated Golgi protein - - - 0.0000000000000000000000002733 112.0
PYH2_k127_2406237_7 Sel1 domain protein repeat-containing protein K07126 - - 0.00000007473 62.0
PYH2_k127_2411424_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.19e-264 827.0
PYH2_k127_2411424_1 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 606.0
PYH2_k127_2411424_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 460.0
PYH2_k127_2411424_3 PFAM Serine threonine protein kinase-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 397.0
PYH2_k127_2411424_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000004423 251.0
PYH2_k127_2411424_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0005401 43.0
PYH2_k127_2429224_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.671e-303 949.0
PYH2_k127_2429224_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.083e-220 696.0
PYH2_k127_2429224_10 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004297 247.0
PYH2_k127_2429224_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
PYH2_k127_2429224_12 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000008724 208.0
PYH2_k127_2429224_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002645 190.0
PYH2_k127_2429224_14 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.00000000000000000000000000000000000000000000007579 183.0
PYH2_k127_2429224_15 - - - - 0.000000000000000000000000000000000000000002179 158.0
PYH2_k127_2429224_16 Multicopper oxidase - - - 0.0000000000000000000000000000000000002103 158.0
PYH2_k127_2429224_17 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000004468 137.0
PYH2_k127_2429224_18 - - - - 0.0000000000000000000000000000005887 127.0
PYH2_k127_2429224_19 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000002171 106.0
PYH2_k127_2429224_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.083e-214 672.0
PYH2_k127_2429224_20 - - - - 0.00000001397 59.0
PYH2_k127_2429224_21 - - - - 0.000001302 55.0
PYH2_k127_2429224_22 - - - - 0.00005664 47.0
PYH2_k127_2429224_23 - - - - 0.0001187 48.0
PYH2_k127_2429224_24 Belongs to the isocitrate lyase PEP mutase superfamily. Methylisocitrate lyase family - - - 0.0001843 46.0
PYH2_k127_2429224_3 Extracellular solute-binding protein K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 599.0
PYH2_k127_2429224_4 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 596.0
PYH2_k127_2429224_5 DNA integration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 553.0
PYH2_k127_2429224_6 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 498.0
PYH2_k127_2429224_7 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 452.0
PYH2_k127_2429224_8 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 412.0
PYH2_k127_2429224_9 Domain of unknown function (DUF927) K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 313.0
PYH2_k127_2489618_0 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 349.0
PYH2_k127_2489618_1 [2Fe-2S] binding domain K04107 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000002354 234.0
PYH2_k127_2489618_2 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000000000000000000000000207 229.0
PYH2_k127_2489618_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000008492 157.0
PYH2_k127_2489618_4 transcriptional regulator - - - 0.0000000000000000000000000000000001207 137.0
PYH2_k127_2489618_5 Thioesterase - - - 0.0000000000000000000000000000004474 128.0
PYH2_k127_2517454_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1291.0
PYH2_k127_2517454_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 9.765e-222 694.0
PYH2_k127_2517454_10 squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
PYH2_k127_2517454_11 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005793 275.0
PYH2_k127_2517454_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000000000001462 171.0
PYH2_k127_2517454_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.426e-219 695.0
PYH2_k127_2517454_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 562.0
PYH2_k127_2517454_4 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 503.0
PYH2_k127_2517454_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 471.0
PYH2_k127_2517454_6 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 404.0
PYH2_k127_2517454_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 373.0
PYH2_k127_2517454_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 338.0
PYH2_k127_2517454_9 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 310.0
PYH2_k127_252366_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 7.273e-268 843.0
PYH2_k127_252366_1 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.534e-202 637.0
PYH2_k127_252366_10 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000003411 210.0
PYH2_k127_252366_11 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000004243 184.0
PYH2_k127_252366_12 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000001824 184.0
PYH2_k127_252366_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000008231 173.0
PYH2_k127_252366_14 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000005275 127.0
PYH2_k127_252366_2 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 540.0
PYH2_k127_252366_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 522.0
PYH2_k127_252366_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 487.0
PYH2_k127_252366_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 453.0
PYH2_k127_252366_6 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 400.0
PYH2_k127_252366_7 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004568 255.0
PYH2_k127_252366_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000002927 235.0
PYH2_k127_252366_9 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
PYH2_k127_2526547_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 572.0
PYH2_k127_2526547_1 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000007058 209.0
PYH2_k127_2526547_2 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000006744 100.0
PYH2_k127_2526547_3 Acetyl-CoA carboxylase, central region - - - 0.000000000000000003588 85.0
PYH2_k127_2526547_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000008206 70.0
PYH2_k127_2526547_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0005536 46.0
PYH2_k127_2532448_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 3.733e-263 826.0
PYH2_k127_2532448_1 Dehydrogenase K15515 - 1.2.1.81 2.035e-210 662.0
PYH2_k127_2532448_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.829e-208 658.0
PYH2_k127_2532448_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 488.0
PYH2_k127_2532448_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000003963 156.0
PYH2_k127_2532448_5 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000003744 140.0
PYH2_k127_2532448_6 Transcriptional regulator IclR - - - 0.0000000000000000002463 94.0
PYH2_k127_253650_0 Putative helicase K12070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 492.0
PYH2_k127_253650_1 TraM recognition site of TraD and TraG K12071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001515 257.0
PYH2_k127_253650_2 Flagellar transcriptional activator (FlhC) - - - 0.00000000000000000000000000000007831 134.0
PYH2_k127_253650_3 PFAM peptidase S24, S26A - - - 0.00000000000000000008839 99.0
PYH2_k127_253650_4 - - - - 0.00002192 53.0
PYH2_k127_253650_5 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00006946 49.0
PYH2_k127_2538613_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.492e-310 960.0
PYH2_k127_2538613_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 9.969e-253 784.0
PYH2_k127_2538613_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 574.0
PYH2_k127_2538613_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
PYH2_k127_2538613_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 335.0
PYH2_k127_2538613_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009591 261.0
PYH2_k127_2538613_6 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000001125 223.0
PYH2_k127_2538613_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000001592 184.0
PYH2_k127_2538613_8 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000002209 185.0
PYH2_k127_2538613_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000001904 81.0
PYH2_k127_2577183_0 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.092e-201 636.0
PYH2_k127_2577183_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 411.0
PYH2_k127_2577183_2 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 320.0
PYH2_k127_2577183_3 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
PYH2_k127_2577183_4 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004979 260.0
PYH2_k127_2586660_0 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 592.0
PYH2_k127_2586660_1 Pfam:DUF989 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 573.0
PYH2_k127_2586660_2 Basic membrane lipoprotein K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000291 220.0
PYH2_k127_2586660_3 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000004976 175.0
PYH2_k127_2586660_4 - - - - 0.000000000000000000000001781 110.0
PYH2_k127_2623699_0 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 513.0
PYH2_k127_2623699_1 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 408.0
PYH2_k127_2623699_2 mechanosensitive K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 352.0
PYH2_k127_2623699_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000007597 144.0
PYH2_k127_2623699_4 TIGRFAM DNA repair protein RadC K03630 - - 0.0000000000000000000000000000000000005231 140.0
PYH2_k127_2623699_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000953 101.0
PYH2_k127_2651987_0 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 282.0
PYH2_k127_2651987_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001286 278.0
PYH2_k127_2654680_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1310.0
PYH2_k127_2654680_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1270.0
PYH2_k127_2654680_10 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 385.0
PYH2_k127_2654680_11 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 375.0
PYH2_k127_2654680_12 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 363.0
PYH2_k127_2654680_13 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
PYH2_k127_2654680_14 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
PYH2_k127_2654680_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 309.0
PYH2_k127_2654680_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002577 278.0
PYH2_k127_2654680_17 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
PYH2_k127_2654680_18 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008755 252.0
PYH2_k127_2654680_19 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
PYH2_k127_2654680_2 DNA helicase K03657 - 3.6.4.12 0.0 1030.0
PYH2_k127_2654680_20 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000005906 221.0
PYH2_k127_2654680_21 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000001281 165.0
PYH2_k127_2654680_22 Prokaryotic N-terminal methylation motif K02655 - - 0.0000000000000000000000000000000000003113 146.0
PYH2_k127_2654680_23 - - - - 0.000000000000000000000000000001299 131.0
PYH2_k127_2654680_3 Pilus retraction K02669,K12203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 577.0
PYH2_k127_2654680_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 582.0
PYH2_k127_2654680_5 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 580.0
PYH2_k127_2654680_6 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 572.0
PYH2_k127_2654680_7 Tat pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 481.0
PYH2_k127_2654680_8 THUMP domain K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
PYH2_k127_2654680_9 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 421.0
PYH2_k127_2675993_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 550.0
PYH2_k127_2675993_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 326.0
PYH2_k127_2675993_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000236 89.0
PYH2_k127_2675993_3 methyltransferase - - - 0.0000000000008714 73.0
PYH2_k127_271730_0 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 372.0
PYH2_k127_271730_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000001765 212.0
PYH2_k127_271730_2 Double zinc ribbon - - - 0.000307 51.0
PYH2_k127_2781540_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1403.0
PYH2_k127_2781540_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.658e-304 940.0
PYH2_k127_2781540_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009644 269.0
PYH2_k127_2781540_11 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002451 268.0
PYH2_k127_2781540_12 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 262.0
PYH2_k127_2781540_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000001128 153.0
PYH2_k127_2781540_14 OmpA family K03286 - - 0.00000000000006245 77.0
PYH2_k127_2781540_15 Helix-hairpin-helix motif K02237 - - 0.000000000006319 74.0
PYH2_k127_2781540_16 Lipopolysaccharide assembly protein A domain K08992 - - 0.000002842 56.0
PYH2_k127_2781540_17 cysteine synthase K01738 - 2.5.1.47 0.0004679 46.0
PYH2_k127_2781540_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.316e-290 897.0
PYH2_k127_2781540_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 518.0
PYH2_k127_2781540_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 502.0
PYH2_k127_2781540_5 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 483.0
PYH2_k127_2781540_6 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 475.0
PYH2_k127_2781540_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 477.0
PYH2_k127_2781540_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 375.0
PYH2_k127_2781540_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 331.0
PYH2_k127_2782858_0 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 1.675e-241 757.0
PYH2_k127_2782858_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.636e-217 686.0
PYH2_k127_2782858_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 526.0
PYH2_k127_2782858_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 480.0
PYH2_k127_2782858_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 432.0
PYH2_k127_2782858_5 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 408.0
PYH2_k127_2782858_6 - - - - 0.000000000000000000000000008933 115.0
PYH2_k127_2802027_0 helicase K03657 - 3.6.4.12 1.758e-292 912.0
PYH2_k127_2802027_1 phospholipase C - - - 2.326e-226 721.0
PYH2_k127_2802027_10 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000001759 95.0
PYH2_k127_2802027_11 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000001754 67.0
PYH2_k127_2802027_2 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 457.0
PYH2_k127_2802027_3 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 426.0
PYH2_k127_2802027_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 363.0
PYH2_k127_2802027_5 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 343.0
PYH2_k127_2802027_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000006807 246.0
PYH2_k127_2802027_7 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000009465 234.0
PYH2_k127_2802027_8 Aminotransferase K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000005092 184.0
PYH2_k127_2802027_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000002059 172.0
PYH2_k127_2809385_0 Damage-inducible protein DinB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002967 254.0
PYH2_k127_2809385_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000005383 197.0
PYH2_k127_2809385_2 ORF6N domain - - - 0.000000000000000000000000000000001639 132.0
PYH2_k127_2832231_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.632e-303 943.0
PYH2_k127_2832231_1 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 560.0
PYH2_k127_2832231_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 340.0
PYH2_k127_2832231_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 318.0
PYH2_k127_2832231_12 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 291.0
PYH2_k127_2832231_13 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 287.0
PYH2_k127_2832231_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006969 291.0
PYH2_k127_2832231_15 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004182 252.0
PYH2_k127_2832231_17 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000001911 191.0
PYH2_k127_2832231_18 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000009579 179.0
PYH2_k127_2832231_19 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000009897 181.0
PYH2_k127_2832231_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 524.0
PYH2_k127_2832231_20 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.0000000000000000000000000000004853 128.0
PYH2_k127_2832231_21 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000002544 96.0
PYH2_k127_2832231_22 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000003183 87.0
PYH2_k127_2832231_24 chaperone-mediated protein folding - - - 0.000000000001159 79.0
PYH2_k127_2832231_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 519.0
PYH2_k127_2832231_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 474.0
PYH2_k127_2832231_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 468.0
PYH2_k127_2832231_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 460.0
PYH2_k127_2832231_7 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 448.0
PYH2_k127_2832231_8 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 462.0
PYH2_k127_2832231_9 Aldo/keto reductase family - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 351.0
PYH2_k127_2833538_0 type II restriction enzyme, methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
PYH2_k127_2833538_1 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000000000006011 199.0
PYH2_k127_2833538_10 - - - - 0.0002967 48.0
PYH2_k127_2833538_2 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000011 176.0
PYH2_k127_2833538_3 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000001714 157.0
PYH2_k127_2833538_4 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000001197 145.0
PYH2_k127_2833538_5 Mut7-C RNAse domain - - - 0.0000000000000000000000000000000008315 132.0
PYH2_k127_2833538_6 type II restriction enzyme, methylase - - - 0.000000000000000000000000000000001181 134.0
PYH2_k127_2833538_7 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000008604 116.0
PYH2_k127_2833538_8 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.00000000000000000000001475 107.0
PYH2_k127_2833538_9 Protein conserved in bacteria - - - 0.0000000000000000000007101 95.0
PYH2_k127_2840624_0 Protein of unknown function, DUF480 - - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
PYH2_k127_2840624_1 Subtilase family - - - 0.00000000000000000000000000007302 123.0
PYH2_k127_2846322_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 1.667e-282 876.0
PYH2_k127_2846322_1 formate dehydrogenase K00123 - 1.17.1.9 2.029e-261 810.0
PYH2_k127_2846322_10 alginic acid biosynthetic process K12287 - - 0.0000000000000000000000000000000000000000000000002156 203.0
PYH2_k127_2846322_11 Prokaryotic N-terminal methylation motif K12285 - - 0.000000000000000000000000000000000000000000000002153 183.0
PYH2_k127_2846322_12 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000007583 156.0
PYH2_k127_2846322_13 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000001014 126.0
PYH2_k127_2846322_14 Prokaryotic N-terminal methylation motif K10924 - - 0.0000000000000000000000000001333 120.0
PYH2_k127_2846322_15 Pilus assembly protein PilX K12286 - - 0.0000000000000000000000001792 114.0
PYH2_k127_2846322_16 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.00000000000000000000006988 100.0
PYH2_k127_2846322_17 Pilus assembly protein K12279 - - 0.00000000000000000002194 102.0
PYH2_k127_2846322_18 Tfp pilus assembly protein FimT K10926 - - 0.0000000000000003079 87.0
PYH2_k127_2846322_19 PFAM Fimbrial assembly family protein - - - 0.0000000000001311 79.0
PYH2_k127_2846322_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.332e-237 752.0
PYH2_k127_2846322_20 carbon utilization K12280 - - 0.0000000000004739 79.0
PYH2_k127_2846322_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 584.0
PYH2_k127_2846322_4 type II and III secretion system protein K02453,K12282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 503.0
PYH2_k127_2846322_5 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 460.0
PYH2_k127_2846322_6 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 375.0
PYH2_k127_2846322_7 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 317.0
PYH2_k127_2846322_8 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 322.0
PYH2_k127_2846322_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002561 282.0
PYH2_k127_2921492_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 460.0
PYH2_k127_2921492_1 ATP synthase subunit D K02120 - - 0.0000000000000002168 81.0
PYH2_k127_2934182_0 Circularly permuted ATP-grasp type 2 - - - 1.119e-245 766.0
PYH2_k127_2934182_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000005428 173.0
PYH2_k127_2934182_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000001688 70.0
PYH2_k127_2934182_3 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00003837 49.0
PYH2_k127_2985_0 PFAM Filamentation induced by cAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 516.0
PYH2_k127_2985_1 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003738 233.0
PYH2_k127_2985_10 Protein of unknown function (DUF433) - - - 0.000000000000000001782 88.0
PYH2_k127_2985_11 N-6 DNA methylase K03427 - 2.1.1.72 0.00000000002014 68.0
PYH2_k127_2985_2 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000000000000000003771 217.0
PYH2_k127_2985_3 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000000000000000000003073 189.0
PYH2_k127_2985_4 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000007775 184.0
PYH2_k127_2985_5 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000532 130.0
PYH2_k127_2985_6 Mut7-C RNAse domain - - - 0.000000000000000000000000000000005694 133.0
PYH2_k127_2985_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000002607 101.0
PYH2_k127_2985_8 PFAM Filamentation induced by cAMP - - - 0.00000000000000000000004192 102.0
PYH2_k127_2985_9 - - - - 0.000000000000000000001016 98.0
PYH2_k127_2985391_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1165.0
PYH2_k127_2985391_1 DNA polymerase III K02342 - 2.7.7.7 8.41e-264 830.0
PYH2_k127_2985391_10 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000005773 181.0
PYH2_k127_2985391_11 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000002696 135.0
PYH2_k127_2985391_12 Protein of unknown function (DUF2905) - - - 0.000000000000000007451 85.0
PYH2_k127_2985391_13 - - - - 0.00000000000001006 76.0
PYH2_k127_2985391_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 569.0
PYH2_k127_2985391_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 554.0
PYH2_k127_2985391_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 457.0
PYH2_k127_2985391_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 390.0
PYH2_k127_2985391_6 Nad-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 334.0
PYH2_k127_2985391_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 328.0
PYH2_k127_2985391_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
PYH2_k127_2985391_9 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000004984 181.0
PYH2_k127_2991594_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 1.438e-196 639.0
PYH2_k127_2991594_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 514.0
PYH2_k127_2991594_2 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 490.0
PYH2_k127_2991594_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 432.0
PYH2_k127_2991594_4 utilization protein B K13795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 423.0
PYH2_k127_2991594_5 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 343.0
PYH2_k127_2991594_6 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 301.0
PYH2_k127_2991594_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002038 263.0
PYH2_k127_3016064_0 CoA-substrate-specific enzyme activase - - - 0.0 1937.0
PYH2_k127_3016064_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.067e-318 992.0
PYH2_k127_3016064_10 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 430.0
PYH2_k127_3016064_11 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 361.0
PYH2_k127_3016064_12 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 338.0
PYH2_k127_3016064_13 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 308.0
PYH2_k127_3016064_14 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 292.0
PYH2_k127_3016064_15 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 253.0
PYH2_k127_3016064_16 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000000000000000000005647 234.0
PYH2_k127_3016064_17 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000006066 213.0
PYH2_k127_3016064_18 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000009683 153.0
PYH2_k127_3016064_19 - - - - 0.00000000000000000000000000000005663 132.0
PYH2_k127_3016064_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.215e-256 803.0
PYH2_k127_3016064_20 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000001001 124.0
PYH2_k127_3016064_21 Protein of unknown function (DUF504) - - - 0.000000000000000000000000003705 114.0
PYH2_k127_3016064_22 GYD domain - - - 0.00000000000000000004888 95.0
PYH2_k127_3016064_23 Protein required for attachment to host cells - - - 0.0000000000000000000669 95.0
PYH2_k127_3016064_25 - - - - 0.000005742 55.0
PYH2_k127_3016064_26 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000127 51.0
PYH2_k127_3016064_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 4.977e-244 769.0
PYH2_k127_3016064_4 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 1.846e-224 706.0
PYH2_k127_3016064_5 Dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 1.044e-199 627.0
PYH2_k127_3016064_6 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 595.0
PYH2_k127_3016064_7 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 560.0
PYH2_k127_3016064_8 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 549.0
PYH2_k127_3016064_9 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 434.0
PYH2_k127_3021927_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
PYH2_k127_3021927_1 dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001268 271.0
PYH2_k127_3021927_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000004281 260.0
PYH2_k127_3021927_3 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009493 248.0
PYH2_k127_3021927_4 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000000000002856 165.0
PYH2_k127_3021927_5 Methyltransferase domain - - - 0.000000000000000008735 89.0
PYH2_k127_302472_0 PFAM ABC transporter related K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 382.0
PYH2_k127_302472_1 Transport permease protein K01992,K09690 - - 0.000000000000000000000000000000000000000000005968 170.0
PYH2_k127_302472_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000003767 138.0
PYH2_k127_3072742_0 ABC transporter K10441 - 3.6.3.17 1.388e-222 698.0
PYH2_k127_3072742_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 511.0
PYH2_k127_3072742_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 344.0
PYH2_k127_3072742_3 - - - - 0.00000000000000000000000000000000000000000000000000000008376 199.0
PYH2_k127_3072742_4 Putative lumazine-binding - - - 0.00000000000000000000000000000000000000000000000000002799 194.0
PYH2_k127_3122607_0 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 9.188e-221 692.0
PYH2_k127_3122607_1 e3 binding domain K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 389.0
PYH2_k127_3122607_2 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
PYH2_k127_3122607_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000765 198.0
PYH2_k127_3122607_4 Ribbon-helix-helix domain - - - 0.00000000000000000000000000000000000000000248 158.0
PYH2_k127_3122607_5 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000001388 70.0
PYH2_k127_3151989_0 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 513.0
PYH2_k127_3167649_0 FAD dependent oxidoreductase central domain - - - 0.0 1219.0
PYH2_k127_3167649_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 535.0
PYH2_k127_3209897_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 505.0
PYH2_k127_3209897_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
PYH2_k127_3209897_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000001889 205.0
PYH2_k127_3209897_3 - - - - 0.00000000000000000000000000000000000000004598 160.0
PYH2_k127_3209897_4 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000001187 118.0
PYH2_k127_3209897_5 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000123 86.0
PYH2_k127_3209897_6 TonB-dependent heme hemoglobin receptor family protein K16087 - - 0.0000000002743 66.0
PYH2_k127_3210986_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 332.0
PYH2_k127_3210986_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000009635 168.0
PYH2_k127_3210986_2 Auxin binding protein - - - 0.0000000000000000000000000000000000000000000319 166.0
PYH2_k127_3210986_3 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000009963 51.0
PYH2_k127_3223448_0 Highly conserved protein containing a thioredoxin domain K06888 - - 9.021e-236 751.0
PYH2_k127_3223448_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 467.0
PYH2_k127_3223448_2 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 417.0
PYH2_k127_3223448_3 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 315.0
PYH2_k127_3223448_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
PYH2_k127_3223448_5 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000218 132.0
PYH2_k127_3223448_6 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000001564 130.0
PYH2_k127_3223448_7 - - - - 0.00000000000000000000007774 99.0
PYH2_k127_3243581_0 peptidase U62, modulator of DNA gyrase K03568 - - 2.245e-217 685.0
PYH2_k127_3243581_1 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 389.0
PYH2_k127_3243581_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 362.0
PYH2_k127_3254792_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 367.0
PYH2_k127_3254792_1 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000005483 181.0
PYH2_k127_3254792_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000004244 149.0
PYH2_k127_3254792_3 AMP-binding enzyme K12508 - 6.2.1.34 0.00000000000002414 75.0
PYH2_k127_3254792_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.00000000001568 64.0
PYH2_k127_3254792_5 AMP-binding enzyme K12508 - 6.2.1.34 0.00000000005024 73.0
PYH2_k127_3290909_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 284.0
PYH2_k127_3290909_1 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
PYH2_k127_3290909_2 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000009038 225.0
PYH2_k127_3290909_3 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000002685 157.0
PYH2_k127_3290909_4 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000004361 108.0
PYH2_k127_3290909_5 Methyltransferase K08316 - 2.1.1.171 0.000000000654 62.0
PYH2_k127_3294418_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5e-324 998.0
PYH2_k127_3294418_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 5.922e-282 877.0
PYH2_k127_3294418_10 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 387.0
PYH2_k127_3294418_11 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 359.0
PYH2_k127_3294418_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 353.0
PYH2_k127_3294418_13 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
PYH2_k127_3294418_14 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
PYH2_k127_3294418_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
PYH2_k127_3294418_16 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 309.0
PYH2_k127_3294418_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000047 280.0
PYH2_k127_3294418_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001219 257.0
PYH2_k127_3294418_19 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 254.0
PYH2_k127_3294418_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.913e-247 780.0
PYH2_k127_3294418_20 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002742 267.0
PYH2_k127_3294418_21 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
PYH2_k127_3294418_22 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000004871 241.0
PYH2_k127_3294418_23 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000002489 216.0
PYH2_k127_3294418_24 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000003896 160.0
PYH2_k127_3294418_25 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000009099 150.0
PYH2_k127_3294418_26 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000009519 135.0
PYH2_k127_3294418_27 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000002759 112.0
PYH2_k127_3294418_28 Domain of unknown function (DUF4845) - - - 0.00000000000000000000001732 104.0
PYH2_k127_3294418_29 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000006551 97.0
PYH2_k127_3294418_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.579e-205 643.0
PYH2_k127_3294418_30 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.0000000000003486 77.0
PYH2_k127_3294418_31 - - - - 0.000000000004007 69.0
PYH2_k127_3294418_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 548.0
PYH2_k127_3294418_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 446.0
PYH2_k127_3294418_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 441.0
PYH2_k127_3294418_7 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 411.0
PYH2_k127_3294418_8 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 394.0
PYH2_k127_3294418_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 386.0
PYH2_k127_3296773_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1321.0
PYH2_k127_3296773_1 amp-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 511.0
PYH2_k127_3296773_2 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 335.0
PYH2_k127_3296773_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
PYH2_k127_3296773_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 297.0
PYH2_k127_3296773_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000257 250.0
PYH2_k127_3296773_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
PYH2_k127_3306316_0 Peptidase C39 family K11004 - - 0.0 1043.0
PYH2_k127_3306316_1 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 550.0
PYH2_k127_3306316_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000005027 184.0
PYH2_k127_3306316_3 ORF located using - - - 0.000000000001075 76.0
PYH2_k127_3306316_4 Two component transcriptional regulator, LuxR family - - - 0.000000309 55.0
PYH2_k127_3310630_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.514e-311 965.0
PYH2_k127_3310630_1 heat shock protein binding - - - 2.719e-260 823.0
PYH2_k127_3310630_10 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000143 111.0
PYH2_k127_3310630_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000001055 57.0
PYH2_k127_3310630_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 385.0
PYH2_k127_3310630_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
PYH2_k127_3310630_4 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 305.0
PYH2_k127_3310630_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
PYH2_k127_3310630_6 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005495 244.0
PYH2_k127_3310630_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000184 240.0
PYH2_k127_3310630_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000007039 205.0
PYH2_k127_3310630_9 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000005017 155.0
PYH2_k127_3369245_0 ATPase involved in DNA repair - - - 0.0 1187.0
PYH2_k127_3369245_1 ribosome binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 433.0
PYH2_k127_3426842_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 543.0
PYH2_k127_3426842_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000002767 149.0
PYH2_k127_3426842_2 - - - - 0.00000000000000000000000001731 111.0
PYH2_k127_3430002_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 3.071e-317 976.0
PYH2_k127_3430002_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.356e-271 846.0
PYH2_k127_3430002_10 - - - - 0.0000000000008586 72.0
PYH2_k127_3430002_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 491.0
PYH2_k127_3430002_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 350.0
PYH2_k127_3430002_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 330.0
PYH2_k127_3430002_5 ArgK protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
PYH2_k127_3430002_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000000000000000000002665 119.0
PYH2_k127_3430002_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000004511 94.0
PYH2_k127_3430002_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000007981 87.0
PYH2_k127_3430002_9 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000003154 74.0
PYH2_k127_3437174_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000348 293.0
PYH2_k127_3437174_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000007131 221.0
PYH2_k127_3437174_2 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000004003 161.0
PYH2_k127_3437174_3 Glycosyltransferase like family 2 K13005 - 2.4.1.60 0.0000000000000000000000000000000000007558 152.0
PYH2_k127_3459947_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 284.0
PYH2_k127_3459947_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000003471 247.0
PYH2_k127_3459947_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000656 138.0
PYH2_k127_3459947_3 PFAM PIN domain - - - 0.0000000000000000000000001193 111.0
PYH2_k127_3459947_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000004651 57.0
PYH2_k127_3479542_0 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 436.0
PYH2_k127_3479542_1 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 386.0
PYH2_k127_3479542_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000009713 234.0
PYH2_k127_3484897_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
PYH2_k127_3484897_1 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000003118 179.0
PYH2_k127_3484897_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001356 173.0
PYH2_k127_3484897_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000002649 131.0
PYH2_k127_3484897_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000001111 59.0
PYH2_k127_3566649_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.338e-242 766.0
PYH2_k127_3566649_1 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 4.173e-222 701.0
PYH2_k127_3566649_10 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000001876 173.0
PYH2_k127_3566649_11 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000008881 152.0
PYH2_k127_3566649_12 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000002656 137.0
PYH2_k127_3566649_13 cellulase activity - - - 0.0000000000000000000002105 112.0
PYH2_k127_3566649_14 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000001293 97.0
PYH2_k127_3566649_15 Protein of unknown function (DUF1223) - - - 0.00006198 49.0
PYH2_k127_3566649_2 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 583.0
PYH2_k127_3566649_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 433.0
PYH2_k127_3566649_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 351.0
PYH2_k127_3566649_5 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
PYH2_k127_3566649_6 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
PYH2_k127_3566649_7 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001151 251.0
PYH2_k127_3566649_8 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000147 179.0
PYH2_k127_3566649_9 Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000117 171.0
PYH2_k127_366014_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 511.0
PYH2_k127_366014_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 464.0
PYH2_k127_366014_10 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000001395 124.0
PYH2_k127_366014_11 - - - - 0.00000000003379 71.0
PYH2_k127_366014_2 PFAM aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 311.0
PYH2_k127_366014_3 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007573 284.0
PYH2_k127_366014_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006483 270.0
PYH2_k127_366014_5 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 269.0
PYH2_k127_366014_6 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000001801 240.0
PYH2_k127_366014_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000001854 166.0
PYH2_k127_366014_8 Thioredoxin-like - - - 0.000000000000000000000000000000000000000003178 171.0
PYH2_k127_366014_9 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000004871 124.0
PYH2_k127_3678299_0 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 390.0
PYH2_k127_3678299_1 ABC transporter - - - 0.000000000005175 69.0
PYH2_k127_3684968_0 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 310.0
PYH2_k127_3684968_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 299.0
PYH2_k127_3684968_2 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000001658 203.0
PYH2_k127_3684968_3 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.000000000000000000000000000000000000000000000000004151 190.0
PYH2_k127_3684968_4 heptosyltransferase K02843 - - 0.00000000000000000000000000000000000005148 149.0
PYH2_k127_3684968_5 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000001301 143.0
PYH2_k127_373012_0 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 371.0
PYH2_k127_373012_1 DDE superfamily endonuclease K07494 - - 0.00000000000000305 77.0
PYH2_k127_3752190_0 PFAM major facilitator superfamily MFS_1 K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 585.0
PYH2_k127_3752190_1 Universal stress protein - - - 0.000000000000000000008631 93.0
PYH2_k127_3754466_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 8.43e-212 672.0
PYH2_k127_3754466_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 609.0
PYH2_k127_3754466_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000001153 160.0
PYH2_k127_3754466_11 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000001068 124.0
PYH2_k127_3754466_12 ferredoxin - - - 0.00000000000000000000000000000442 119.0
PYH2_k127_3754466_13 Putative regulatory protein - - - 0.00000000000000000001843 93.0
PYH2_k127_3754466_2 beta' subunit K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 597.0
PYH2_k127_3754466_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 560.0
PYH2_k127_3754466_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 524.0
PYH2_k127_3754466_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 473.0
PYH2_k127_3754466_6 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 379.0
PYH2_k127_3754466_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 366.0
PYH2_k127_3754466_8 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
PYH2_k127_3754466_9 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 300.0
PYH2_k127_3760170_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.981e-211 664.0
PYH2_k127_3760170_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 604.0
PYH2_k127_3760170_2 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000003212 109.0
PYH2_k127_3762078_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 454.0
PYH2_k127_3762078_1 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 303.0
PYH2_k127_3762078_2 Belongs to the 'phage' integrase family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00001529 52.0
PYH2_k127_376708_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 586.0
PYH2_k127_376708_1 Flagellar assembly protein FliH K02411 - - 0.00000000000000000001133 95.0
PYH2_k127_376708_2 Flagellar hook-length control protein FliK K02414 - - 0.000000000009342 78.0
PYH2_k127_376708_3 flagellar export protein FliJ K02413 - - 0.0000000003962 66.0
PYH2_k127_3773052_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.128e-221 696.0
PYH2_k127_3773052_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 511.0
PYH2_k127_3773052_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
PYH2_k127_3773052_3 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 319.0
PYH2_k127_3773052_4 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000005709 170.0
PYH2_k127_3785691_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 392.0
PYH2_k127_3785691_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000009126 226.0
PYH2_k127_3785691_2 - - - - 0.000000000000000001612 96.0
PYH2_k127_3785691_3 PFAM cytochrome c, class I K08738 - - 0.0000000000002929 73.0
PYH2_k127_3786767_0 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 591.0
PYH2_k127_3786767_1 Transcriptional regulator - - - 0.000000000000277 69.0
PYH2_k127_3786767_2 Bacterial extracellular solute-binding protein K02020 - - 0.00000000001644 67.0
PYH2_k127_3786767_4 Tripartite tricarboxylate transporter family receptor - - - 0.0006689 46.0
PYH2_k127_3791279_0 Prolyl oligopeptidase family - - - 2.736e-220 701.0
PYH2_k127_3791279_1 von Willebrand factor, type A K07114 - - 7.844e-214 683.0
PYH2_k127_3791279_10 - - - - 0.00000000000000000000003571 104.0
PYH2_k127_3791279_11 - - - - 0.000000000000002023 83.0
PYH2_k127_3791279_12 Domain of unknown function (DUF1840) - - - 0.000000000000004712 79.0
PYH2_k127_3791279_13 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000006068 75.0
PYH2_k127_3791279_2 Sulfatase - - - 7.274e-213 682.0
PYH2_k127_3791279_3 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 465.0
PYH2_k127_3791279_4 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 270.0
PYH2_k127_3791279_5 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
PYH2_k127_3791279_6 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000007994 233.0
PYH2_k127_3791279_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000001554 220.0
PYH2_k127_3791279_8 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000003412 174.0
PYH2_k127_3791279_9 - - - - 0.0000000000000000000000000000000000002675 158.0
PYH2_k127_3793301_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 369.0
PYH2_k127_3793301_1 histidine kinase A domain protein K15011 - 2.7.13.3 0.0000000000000000000002913 106.0
PYH2_k127_379702_0 Belongs to the peptidase M12A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 527.0
PYH2_k127_379702_1 Ribosomal protein S6 modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 435.0
PYH2_k127_379702_2 Domain of unknown function (DUF932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 287.0
PYH2_k127_379702_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003454 267.0
PYH2_k127_379702_4 Domain of unknown function (DUF932) - - - 0.000000000000000000000000000000000000000000000000000000000001127 221.0
PYH2_k127_3797447_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 6.384e-226 721.0
PYH2_k127_3797447_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.862e-221 693.0
PYH2_k127_3797447_10 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 355.0
PYH2_k127_3797447_11 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 289.0
PYH2_k127_3797447_12 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001641 284.0
PYH2_k127_3797447_13 (FHA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH2_k127_3797447_14 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
PYH2_k127_3797447_15 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
PYH2_k127_3797447_16 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000007284 213.0
PYH2_k127_3797447_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000007408 156.0
PYH2_k127_3797447_18 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000000000000000000000000000001073 147.0
PYH2_k127_3797447_19 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000003014 139.0
PYH2_k127_3797447_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.482e-203 637.0
PYH2_k127_3797447_20 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000006789 136.0
PYH2_k127_3797447_21 - - - - 0.00000000002762 68.0
PYH2_k127_3797447_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 584.0
PYH2_k127_3797447_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 548.0
PYH2_k127_3797447_5 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 532.0
PYH2_k127_3797447_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 508.0
PYH2_k127_3797447_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 490.0
PYH2_k127_3797447_8 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 444.0
PYH2_k127_3797447_9 Mg2 and Co2 transporter K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 392.0
PYH2_k127_3798487_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.375e-268 845.0
PYH2_k127_3798487_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.272e-238 743.0
PYH2_k127_3798487_10 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000006188 170.0
PYH2_k127_3798487_11 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000001102 162.0
PYH2_k127_3798487_12 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000154 133.0
PYH2_k127_3798487_13 Mitomycin resistance protein K07343 - - 0.00000000000000001167 90.0
PYH2_k127_3798487_14 regulator - - - 0.00000000000009136 79.0
PYH2_k127_3798487_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.983e-224 713.0
PYH2_k127_3798487_3 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 579.0
PYH2_k127_3798487_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 570.0
PYH2_k127_3798487_5 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 550.0
PYH2_k127_3798487_6 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 513.0
PYH2_k127_3798487_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 443.0
PYH2_k127_3798487_8 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 289.0
PYH2_k127_3798487_9 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000001052 202.0
PYH2_k127_3805296_0 Proton-conducting membrane transporter K12141 - - 6.078e-248 772.0
PYH2_k127_3805296_1 Transposase DDE domain group 1 - - - 3.714e-210 660.0
PYH2_k127_3805296_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 5.101e-209 661.0
PYH2_k127_3805296_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 474.0
PYH2_k127_3805296_4 NADH ubiquinone plastoquinone (Complex I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 406.0
PYH2_k127_3805296_5 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 316.0
PYH2_k127_3805296_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000732 276.0
PYH2_k127_3805296_7 SmpA / OmlA family - - - 0.00000000000000000000000000000002985 132.0
PYH2_k127_3808361_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.205e-309 968.0
PYH2_k127_3808361_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.898e-273 844.0
PYH2_k127_3808361_10 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.00000000000000002447 89.0
PYH2_k127_3808361_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 555.0
PYH2_k127_3808361_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 362.0
PYH2_k127_3808361_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002859 260.0
PYH2_k127_3808361_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000007452 220.0
PYH2_k127_3808361_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000003724 183.0
PYH2_k127_3808361_7 transcriptional - - - 0.00000000000000000000000000000000000000000000003781 172.0
PYH2_k127_3808361_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000001979 166.0
PYH2_k127_3808361_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000102 108.0
PYH2_k127_3809494_0 PUA-like domain K00958 - 2.7.7.4 6.122e-217 681.0
PYH2_k127_3809494_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 581.0
PYH2_k127_3809494_10 - - - - 0.00000000000005626 76.0
PYH2_k127_3809494_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 482.0
PYH2_k127_3809494_3 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 481.0
PYH2_k127_3809494_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 390.0
PYH2_k127_3809494_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 339.0
PYH2_k127_3809494_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
PYH2_k127_3809494_7 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 308.0
PYH2_k127_3809494_8 PFAM UspA domain protein K07090 - - 0.0000000000000000000000000000000003816 143.0
PYH2_k127_3809494_9 - - - - 0.0000000000000000000000000005212 124.0
PYH2_k127_3816415_0 Belongs to the transketolase family K00615 - 2.2.1.1 3.622e-299 934.0
PYH2_k127_3816415_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.155e-213 676.0
PYH2_k127_3816415_10 PFAM Patatin K07001 - - 0.0000000000000000000000001445 115.0
PYH2_k127_3816415_11 Barstar (barnase inhibitor) - - - 0.00000000000000000000003491 108.0
PYH2_k127_3816415_12 Rhomboid family - - - 0.00000000000000002832 91.0
PYH2_k127_3816415_13 Tricorn protease C1 domain K03797 - 3.4.21.102 0.0000000000003634 78.0
PYH2_k127_3816415_14 Bacterial protein of unknown function (DUF937) - - - 0.0000000000003855 73.0
PYH2_k127_3816415_16 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000001716 55.0
PYH2_k127_3816415_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 594.0
PYH2_k127_3816415_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 597.0
PYH2_k127_3816415_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 476.0
PYH2_k127_3816415_5 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 442.0
PYH2_k127_3816415_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 291.0
PYH2_k127_3816415_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000002506 205.0
PYH2_k127_3816415_8 ribonuclease K01167 - 3.1.27.3 0.0000000000000000000000000000000000000249 148.0
PYH2_k127_3816415_9 Lysin motif - - - 0.000000000000000000000000000005375 132.0
PYH2_k127_3825004_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 402.0
PYH2_k127_3825004_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 354.0
PYH2_k127_3825004_10 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
PYH2_k127_3825004_11 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000001899 218.0
PYH2_k127_3825004_12 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000001608 216.0
PYH2_k127_3825004_13 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000444 205.0
PYH2_k127_3825004_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000005529 208.0
PYH2_k127_3825004_15 TPM domain - - - 0.000000000000000000000000000000000000000000000000004321 186.0
PYH2_k127_3825004_16 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000003411 197.0
PYH2_k127_3825004_17 SnoaL-like domain - - - 0.00000000000000000000000000000000009573 136.0
PYH2_k127_3825004_18 Protein of unknown function (DUF2892) - - - 0.00000000000000000000302 95.0
PYH2_k127_3825004_2 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 331.0
PYH2_k127_3825004_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 319.0
PYH2_k127_3825004_4 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 325.0
PYH2_k127_3825004_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 297.0
PYH2_k127_3825004_6 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 289.0
PYH2_k127_3825004_7 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
PYH2_k127_3825004_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001707 249.0
PYH2_k127_3825004_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
PYH2_k127_3836554_0 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 474.0
PYH2_k127_3836554_1 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000001011 94.0
PYH2_k127_3836554_2 Glycosyl transferase family 2 - - - 0.000000000006145 67.0
PYH2_k127_3836554_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000001185 69.0
PYH2_k127_3840356_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2522.0
PYH2_k127_3840356_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 1.056e-288 907.0
PYH2_k127_3840356_10 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 538.0
PYH2_k127_3840356_11 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 517.0
PYH2_k127_3840356_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 464.0
PYH2_k127_3840356_13 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0003674,GO:0003824,GO:0003920,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016491,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030097,GO:0030099,GO:0030154,GO:0030224,GO:0032501,GO:0032502,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046038,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0048513,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1903131 1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 464.0
PYH2_k127_3840356_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 460.0
PYH2_k127_3840356_15 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 457.0
PYH2_k127_3840356_16 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 456.0
PYH2_k127_3840356_17 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 420.0
PYH2_k127_3840356_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 430.0
PYH2_k127_3840356_19 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 414.0
PYH2_k127_3840356_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.175e-250 780.0
PYH2_k127_3840356_20 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 414.0
PYH2_k127_3840356_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 405.0
PYH2_k127_3840356_22 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 403.0
PYH2_k127_3840356_23 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 385.0
PYH2_k127_3840356_24 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 378.0
PYH2_k127_3840356_25 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 367.0
PYH2_k127_3840356_26 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 366.0
PYH2_k127_3840356_27 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 366.0
PYH2_k127_3840356_28 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 365.0
PYH2_k127_3840356_29 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 348.0
PYH2_k127_3840356_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.518e-236 735.0
PYH2_k127_3840356_30 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
PYH2_k127_3840356_31 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 331.0
PYH2_k127_3840356_32 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 330.0
PYH2_k127_3840356_33 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 322.0
PYH2_k127_3840356_34 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 321.0
PYH2_k127_3840356_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 317.0
PYH2_k127_3840356_36 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 304.0
PYH2_k127_3840356_37 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000156 280.0
PYH2_k127_3840356_38 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 280.0
PYH2_k127_3840356_39 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002225 271.0
PYH2_k127_3840356_4 Secretin and TonB N terminus short domain K02666 - - 1.157e-229 734.0
PYH2_k127_3840356_40 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007217 274.0
PYH2_k127_3840356_41 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002003 260.0
PYH2_k127_3840356_42 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
PYH2_k127_3840356_43 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007562 257.0
PYH2_k127_3840356_44 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003361 247.0
PYH2_k127_3840356_45 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000001538 258.0
PYH2_k127_3840356_46 PFAM cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
PYH2_k127_3840356_47 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000001518 243.0
PYH2_k127_3840356_48 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000001656 228.0
PYH2_k127_3840356_49 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000268 228.0
PYH2_k127_3840356_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.362e-208 657.0
PYH2_k127_3840356_50 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000001045 226.0
PYH2_k127_3840356_51 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000002139 222.0
PYH2_k127_3840356_52 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000112 224.0
PYH2_k127_3840356_53 PFAM Ig domain protein, group 1 domain protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000001267 241.0
PYH2_k127_3840356_54 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000003316 221.0
PYH2_k127_3840356_55 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000001308 211.0
PYH2_k127_3840356_56 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000002801 207.0
PYH2_k127_3840356_57 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000001056 201.0
PYH2_k127_3840356_58 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000001687 196.0
PYH2_k127_3840356_59 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000000000345 192.0
PYH2_k127_3840356_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 605.0
PYH2_k127_3840356_60 Psort location Extracellular, score K07126 - - 0.00000000000000000000000000000000000000000000000000002909 196.0
PYH2_k127_3840356_61 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000002925 186.0
PYH2_k127_3840356_62 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000003478 194.0
PYH2_k127_3840356_63 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000007649 190.0
PYH2_k127_3840356_64 Cupin domain - - - 0.000000000000000000000000000000000000000000000004689 179.0
PYH2_k127_3840356_65 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000004304 175.0
PYH2_k127_3840356_66 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000006026 172.0
PYH2_k127_3840356_67 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001699 165.0
PYH2_k127_3840356_68 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000002991 166.0
PYH2_k127_3840356_69 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000003717 171.0
PYH2_k127_3840356_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 570.0
PYH2_k127_3840356_70 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000003547 163.0
PYH2_k127_3840356_71 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000225 160.0
PYH2_k127_3840356_72 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003194 150.0
PYH2_k127_3840356_73 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000008704 147.0
PYH2_k127_3840356_74 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000001009 149.0
PYH2_k127_3840356_75 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000001084 149.0
PYH2_k127_3840356_76 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000354 145.0
PYH2_k127_3840356_77 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000005642 147.0
PYH2_k127_3840356_78 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000002804 144.0
PYH2_k127_3840356_79 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000000000001959 137.0
PYH2_k127_3840356_8 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 547.0
PYH2_k127_3840356_80 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000000002734 140.0
PYH2_k127_3840356_81 tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000003709 134.0
PYH2_k127_3840356_82 Redoxin domain protein - - - 0.00000000000000000000000000000000473 140.0
PYH2_k127_3840356_83 RNA-binding protein S4 K04762 - - 0.0000000000000000000000000000000629 130.0
PYH2_k127_3840356_84 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000001366 129.0
PYH2_k127_3840356_85 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000009948 120.0
PYH2_k127_3840356_86 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000003755 104.0
PYH2_k127_3840356_87 Ribosomal protein L30 K02907 - - 0.0000000000000000003518 93.0
PYH2_k127_3840356_88 Ribosomal L29 protein K02904 - - 0.00000000000000009356 86.0
PYH2_k127_3840356_89 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000006926 77.0
PYH2_k127_3840356_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 539.0
PYH2_k127_3840356_90 Ribosomal protein L36 K02919 - - 0.000000000000008782 74.0
PYH2_k127_3840356_91 STAS domain K07122 - - 0.0000000000001284 74.0
PYH2_k127_3860191_0 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000028 239.0
PYH2_k127_3860191_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000001727 229.0
PYH2_k127_3860191_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000002741 164.0
PYH2_k127_3881651_0 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 359.0
PYH2_k127_3881651_1 5'-nucleotidase, C-terminal domain K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 343.0
PYH2_k127_3881651_2 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005915 248.0
PYH2_k127_3881651_3 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005151 242.0
PYH2_k127_3881651_4 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000004747 195.0
PYH2_k127_3881651_5 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000005164 168.0
PYH2_k127_3881651_6 oxidation protein K17227 - - 0.00000000000000000000000000000000000000007954 153.0
PYH2_k127_3881651_7 Peptidase S24-like - - - 0.0000000000000000000000000000000003306 136.0
PYH2_k127_3881651_8 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000003378 113.0
PYH2_k127_3881651_9 - - - - 0.000000000000000000003466 95.0
PYH2_k127_3944701_0 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000008071 247.0
PYH2_k127_3952100_0 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 409.0
PYH2_k127_3952100_1 Histone methylation protein DOT1 - - - 0.0000003456 54.0
PYH2_k127_3952100_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00002083 47.0
PYH2_k127_4004190_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1439.0
PYH2_k127_4004190_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.441e-248 771.0
PYH2_k127_4004190_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 377.0
PYH2_k127_4004190_11 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 376.0
PYH2_k127_4004190_12 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
PYH2_k127_4004190_13 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002315 282.0
PYH2_k127_4004190_14 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000008343 225.0
PYH2_k127_4004190_15 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000004491 202.0
PYH2_k127_4004190_16 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000001358 192.0
PYH2_k127_4004190_17 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000004819 156.0
PYH2_k127_4004190_18 sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000002354 131.0
PYH2_k127_4004190_19 Histidine kinase - - - 0.0000000000000000000000000000001208 129.0
PYH2_k127_4004190_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.354e-247 781.0
PYH2_k127_4004190_20 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000007942 117.0
PYH2_k127_4004190_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 599.0
PYH2_k127_4004190_4 Na Pi-cotransporter II-related protein K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 595.0
PYH2_k127_4004190_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 546.0
PYH2_k127_4004190_6 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 495.0
PYH2_k127_4004190_7 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 418.0
PYH2_k127_4004190_8 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 419.0
PYH2_k127_4004190_9 Insertion element 4 transposase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 404.0
PYH2_k127_4005682_0 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 501.0
PYH2_k127_4005682_1 type VI secretion protein K11891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 460.0
PYH2_k127_4005682_2 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 353.0
PYH2_k127_4005682_3 TIGRFAM type VI secretion system FHA domain protein K07169,K11913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 323.0
PYH2_k127_4005682_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 288.0
PYH2_k127_4005682_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 258.0
PYH2_k127_4005682_6 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000001555 167.0
PYH2_k127_4005682_7 Lysin motif - - - 0.0000000000000000000000000000000001059 145.0
PYH2_k127_4011503_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 259.0
PYH2_k127_4011503_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000007086 235.0
PYH2_k127_4011503_2 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
PYH2_k127_4011503_3 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
PYH2_k127_4011503_4 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000001371 211.0
PYH2_k127_4011503_5 - - - - 0.0000000000000000000000000000000000000000000000000000000002609 214.0
PYH2_k127_4011503_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000001087 138.0
PYH2_k127_4015382_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 402.0
PYH2_k127_4015382_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000008844 204.0
PYH2_k127_408059_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 1.087e-228 713.0
PYH2_k127_408059_1 Domain of unknown function (DUF3390) K18929 - - 1.633e-203 651.0
PYH2_k127_408059_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 479.0
PYH2_k127_408059_3 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 347.0
PYH2_k127_408059_4 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001892 282.0
PYH2_k127_408059_5 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000408 203.0
PYH2_k127_408059_6 Cyclase dehydrase - - - 0.00000000000000000000000000000000000002232 156.0
PYH2_k127_408059_7 - - - - 0.000000000000000000000005385 104.0
PYH2_k127_408059_8 NmrA family - - - 0.00003317 47.0
PYH2_k127_408464_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 3.655e-244 763.0
PYH2_k127_408464_1 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 3.589e-224 707.0
PYH2_k127_408464_10 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 382.0
PYH2_k127_408464_11 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 370.0
PYH2_k127_408464_12 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 373.0
PYH2_k127_408464_13 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
PYH2_k127_408464_14 Type ii and iii secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005717 249.0
PYH2_k127_408464_15 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000001086 214.0
PYH2_k127_408464_16 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08319 - 1.1.1.411 0.000000000000000000005732 100.0
PYH2_k127_408464_18 - - - - 0.000000000000001856 82.0
PYH2_k127_408464_19 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.00000000005807 70.0
PYH2_k127_408464_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 569.0
PYH2_k127_408464_21 - - - - 0.000006165 53.0
PYH2_k127_408464_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 528.0
PYH2_k127_408464_4 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 522.0
PYH2_k127_408464_5 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 496.0
PYH2_k127_408464_6 ATPases associated with a variety of cellular activities K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 477.0
PYH2_k127_408464_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 453.0
PYH2_k127_408464_8 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 416.0
PYH2_k127_408464_9 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 411.0
PYH2_k127_4108210_0 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 418.0
PYH2_k127_4108210_1 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 385.0
PYH2_k127_4117993_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 322.0
PYH2_k127_4117993_1 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001987 282.0
PYH2_k127_4117993_2 - - - - 0.0000000000000000000000000000000000000000003506 167.0
PYH2_k127_4117993_3 UPF0391 membrane protein - - - 0.000000000000001295 78.0
PYH2_k127_4117993_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000008347 74.0
PYH2_k127_4117993_6 ribosome binding - - - 0.00000001226 63.0
PYH2_k127_4117993_7 SMART Transport-associated and nodulation region - - - 0.00000002131 61.0
PYH2_k127_4122989_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1216.0
PYH2_k127_4122989_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1115.0
PYH2_k127_4122989_10 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 471.0
PYH2_k127_4122989_11 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 464.0
PYH2_k127_4122989_12 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 444.0
PYH2_k127_4122989_13 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 444.0
PYH2_k127_4122989_14 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
PYH2_k127_4122989_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 426.0
PYH2_k127_4122989_16 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 422.0
PYH2_k127_4122989_17 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 403.0
PYH2_k127_4122989_18 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 404.0
PYH2_k127_4122989_19 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 391.0
PYH2_k127_4122989_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1021.0
PYH2_k127_4122989_20 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 390.0
PYH2_k127_4122989_21 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 392.0
PYH2_k127_4122989_22 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 380.0
PYH2_k127_4122989_23 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 368.0
PYH2_k127_4122989_24 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 342.0
PYH2_k127_4122989_25 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
PYH2_k127_4122989_26 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 325.0
PYH2_k127_4122989_27 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 326.0
PYH2_k127_4122989_28 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003728 277.0
PYH2_k127_4122989_29 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009331 281.0
PYH2_k127_4122989_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.15e-288 898.0
PYH2_k127_4122989_30 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000001929 234.0
PYH2_k127_4122989_31 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
PYH2_k127_4122989_32 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000017 226.0
PYH2_k127_4122989_33 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
PYH2_k127_4122989_34 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000007789 203.0
PYH2_k127_4122989_35 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000008861 203.0
PYH2_k127_4122989_36 Oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000000006957 170.0
PYH2_k127_4122989_37 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000008846 167.0
PYH2_k127_4122989_38 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000006344 155.0
PYH2_k127_4122989_39 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000009605 124.0
PYH2_k127_4122989_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5.892e-286 897.0
PYH2_k127_4122989_40 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000001997 113.0
PYH2_k127_4122989_41 Domain of unknown function (DUF4124) - - - 0.0000000000000000004764 95.0
PYH2_k127_4122989_42 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000009066 75.0
PYH2_k127_4122989_5 ABC transporter C-terminal domain K06158 - - 1.251e-260 816.0
PYH2_k127_4122989_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.568e-198 625.0
PYH2_k127_4122989_7 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 539.0
PYH2_k127_4122989_8 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 516.0
PYH2_k127_4122989_9 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 518.0
PYH2_k127_4123020_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 1.044e-224 700.0
PYH2_k127_4123020_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.6e-206 649.0
PYH2_k127_4123020_10 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 340.0
PYH2_k127_4123020_11 ATPases associated with a variety of cellular activities K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 321.0
PYH2_k127_4123020_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
PYH2_k127_4123020_13 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
PYH2_k127_4123020_14 hydratase K02554 - 4.2.1.80 0.000000000000000000000000000000000001824 148.0
PYH2_k127_4123020_15 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000001367 127.0
PYH2_k127_4123020_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 580.0
PYH2_k127_4123020_3 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 573.0
PYH2_k127_4123020_4 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 516.0
PYH2_k127_4123020_5 Branched-chain amino acid transport system / permease component K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 516.0
PYH2_k127_4123020_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 464.0
PYH2_k127_4123020_7 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 421.0
PYH2_k127_4123020_8 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 387.0
PYH2_k127_4123020_9 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 356.0
PYH2_k127_4124209_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 548.0
PYH2_k127_4124209_1 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 391.0
PYH2_k127_4124209_2 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 310.0
PYH2_k127_4124209_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000001398 61.0
PYH2_k127_4176809_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 3.072e-264 830.0
PYH2_k127_4176809_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 1.928e-241 760.0
PYH2_k127_4176809_2 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 396.0
PYH2_k127_4176809_3 viral genome integration into host DNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 413.0
PYH2_k127_4176809_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 336.0
PYH2_k127_4176809_5 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000005472 188.0
PYH2_k127_4176809_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000002534 141.0
PYH2_k127_4176809_7 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000003104 147.0
PYH2_k127_4176809_8 Alpha beta hydrolase - - - 0.0003961 46.0
PYH2_k127_4202892_0 ribonuclease, Rne Rng family K08301 - - 6.885e-228 716.0
PYH2_k127_4202892_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 575.0
PYH2_k127_4202892_10 Methyltransferase domain - - - 0.000103 53.0
PYH2_k127_4202892_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 512.0
PYH2_k127_4202892_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 492.0
PYH2_k127_4202892_4 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 398.0
PYH2_k127_4202892_5 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 297.0
PYH2_k127_4202892_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000002145 210.0
PYH2_k127_4202892_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000003537 174.0
PYH2_k127_4202892_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000003521 172.0
PYH2_k127_4202892_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000009068 175.0
PYH2_k127_420483_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 333.0
PYH2_k127_420483_1 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000006138 160.0
PYH2_k127_420483_2 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000219 106.0
PYH2_k127_4250918_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.197e-202 637.0
PYH2_k127_4250918_1 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 467.0
PYH2_k127_4250918_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 266.0
PYH2_k127_4250918_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001606 249.0
PYH2_k127_4250918_4 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000000000000000000000000000000000000000000001106 208.0
PYH2_k127_4250918_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
PYH2_k127_4250918_6 Catalyzes the formation of succinate from succinate semialdehyde K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000003565 192.0
PYH2_k127_4250918_7 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000001714 191.0
PYH2_k127_4250918_8 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000006561 85.0
PYH2_k127_4298198_0 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000001852 196.0
PYH2_k127_4298198_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000703 83.0
PYH2_k127_4298198_2 CHAD - - - 0.0000000002473 66.0
PYH2_k127_4348356_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 329.0
PYH2_k127_4348356_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001122 271.0
PYH2_k127_4386064_0 PFAM Glycosyl transferase, family 2 - - - 0.0 1129.0
PYH2_k127_4386064_1 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 4.303e-213 670.0
PYH2_k127_4386064_10 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 499.0
PYH2_k127_4386064_11 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 474.0
PYH2_k127_4386064_12 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 468.0
PYH2_k127_4386064_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 458.0
PYH2_k127_4386064_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 447.0
PYH2_k127_4386064_15 Belongs to the GPI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 410.0
PYH2_k127_4386064_16 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 404.0
PYH2_k127_4386064_17 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
PYH2_k127_4386064_18 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 381.0
PYH2_k127_4386064_19 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 363.0
PYH2_k127_4386064_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 7.003e-211 662.0
PYH2_k127_4386064_20 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 359.0
PYH2_k127_4386064_21 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 367.0
PYH2_k127_4386064_22 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 344.0
PYH2_k127_4386064_23 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 314.0
PYH2_k127_4386064_24 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 306.0
PYH2_k127_4386064_25 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 284.0
PYH2_k127_4386064_26 O-Methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006634 274.0
PYH2_k127_4386064_27 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000459 271.0
PYH2_k127_4386064_28 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003843 270.0
PYH2_k127_4386064_29 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009466 263.0
PYH2_k127_4386064_3 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 591.0
PYH2_k127_4386064_30 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000144 255.0
PYH2_k127_4386064_31 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
PYH2_k127_4386064_32 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 248.0
PYH2_k127_4386064_33 phenylacetic acid degradation protein paaN - - - 0.000000000000000000000000000000000000000000000000000000000000000004956 234.0
PYH2_k127_4386064_34 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000000000000142 222.0
PYH2_k127_4386064_35 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000004311 217.0
PYH2_k127_4386064_36 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.0000000000000000000000000000000000000000000000000000005788 194.0
PYH2_k127_4386064_37 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000008891 198.0
PYH2_k127_4386064_38 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.00000000000000000000000000000000000000000000000004986 186.0
PYH2_k127_4386064_39 Membrane - - - 0.000000000000000000000000000000000000000000000005721 190.0
PYH2_k127_4386064_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 592.0
PYH2_k127_4386064_40 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000007809 184.0
PYH2_k127_4386064_41 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003507 184.0
PYH2_k127_4386064_42 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000001427 138.0
PYH2_k127_4386064_43 transport system permease K01995,K01998 - - 0.0000000000000000000000000000002137 136.0
PYH2_k127_4386064_44 GtrA-like protein - - - 0.000000000000000000000000001519 121.0
PYH2_k127_4386064_45 COGs COG2929 conserved K09803 - - 0.00000000000000000000004415 100.0
PYH2_k127_4386064_46 - - - - 0.000000000000000000009206 108.0
PYH2_k127_4386064_47 Glycosyl transferase family 2 - - - 0.00000000000000003823 86.0
PYH2_k127_4386064_48 GtrA-like protein - - - 0.0000000000000004836 85.0
PYH2_k127_4386064_49 Epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000002433 81.0
PYH2_k127_4386064_5 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 582.0
PYH2_k127_4386064_50 - - - - 0.000000000007635 68.0
PYH2_k127_4386064_51 histidine kinase A domain protein - - - 0.0001409 52.0
PYH2_k127_4386064_52 Phenylacetic acid degradation protein PaaN - - - 0.0007342 50.0
PYH2_k127_4386064_53 repeat-containing protein - - - 0.000752 48.0
PYH2_k127_4386064_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 544.0
PYH2_k127_4386064_7 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 557.0
PYH2_k127_4386064_8 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 516.0
PYH2_k127_4386064_9 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 514.0
PYH2_k127_439228_0 type II secretion system protein E K02454,K02652 - - 5.128e-209 659.0
PYH2_k127_439228_1 Domain of unknown function (DUF4331) - - - 4.856e-195 617.0
PYH2_k127_439228_10 Cytochrome c K08738 - - 0.000000000000000000000000000003982 126.0
PYH2_k127_439228_11 General secretion pathway protein L K02461 - - 0.0000000000000000000000000009698 127.0
PYH2_k127_439228_12 Winged helix-turn helix - - - 0.000000000000000000000000001477 119.0
PYH2_k127_439228_13 general secretion pathway protein K02457 - - 0.00000000000000000000000008021 113.0
PYH2_k127_439228_14 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000000003104 95.0
PYH2_k127_439228_15 ChrR Cupin-like domain - - - 0.000000000000000001872 93.0
PYH2_k127_439228_16 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000007127 92.0
PYH2_k127_439228_17 general secretion pathway protein K02459 - - 0.000000000000000008607 94.0
PYH2_k127_439228_18 General secretion pathway K02462 - - 0.0000000000000001005 86.0
PYH2_k127_439228_19 Anti-sigma factor - - - 0.00000000000002905 78.0
PYH2_k127_439228_2 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 630.0
PYH2_k127_439228_20 general secretion pathway protein K02452 - - 0.0000002927 57.0
PYH2_k127_439228_3 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 434.0
PYH2_k127_439228_4 Domain of unknown function (DUF4439) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004274 236.0
PYH2_k127_439228_5 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000005203 208.0
PYH2_k127_439228_6 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000002465 206.0
PYH2_k127_439228_7 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000007918 188.0
PYH2_k127_439228_8 General Secretory Pathway K02463 - - 0.0000000000000000000000000000000000000000371 161.0
PYH2_k127_439228_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000782 146.0
PYH2_k127_4439193_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.347e-293 916.0
PYH2_k127_4439193_1 Belongs to the glycosyl hydrolase 13 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 594.0
PYH2_k127_4439193_10 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000004543 114.0
PYH2_k127_4439193_11 Protein of unknown function (DUF1015) - - - 0.000000000000000001025 87.0
PYH2_k127_4439193_12 Amidohydrolase - - - 0.000000000000005253 87.0
PYH2_k127_4439193_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
PYH2_k127_4439193_3 Putative heavy-metal chelation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 336.0
PYH2_k127_4439193_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002411 281.0
PYH2_k127_4439193_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008389 239.0
PYH2_k127_4439193_6 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000002805 178.0
PYH2_k127_4439193_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000004328 176.0
PYH2_k127_4439193_8 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000000000004749 155.0
PYH2_k127_450705_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1677.0
PYH2_k127_450705_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.188e-253 801.0
PYH2_k127_450705_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000002264 159.0
PYH2_k127_450705_11 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000000664 159.0
PYH2_k127_450705_12 - - - - 0.0000000000000000000003642 105.0
PYH2_k127_450705_13 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000008987 74.0
PYH2_k127_450705_14 Domain of unknown function (DUF1902) - - - 0.0004888 47.0
PYH2_k127_450705_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 602.0
PYH2_k127_450705_3 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 589.0
PYH2_k127_450705_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 475.0
PYH2_k127_450705_5 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 432.0
PYH2_k127_450705_6 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 323.0
PYH2_k127_450705_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH2_k127_450705_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001657 208.0
PYH2_k127_450705_9 Protein of unknown function (DUF2459) - - - 0.00000000000000000000000000000000000000000003524 171.0
PYH2_k127_4531659_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1207.0
PYH2_k127_4531659_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 411.0
PYH2_k127_4531659_2 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 387.0
PYH2_k127_4531659_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
PYH2_k127_4531659_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 303.0
PYH2_k127_4531659_5 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
PYH2_k127_4531659_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005121 260.0
PYH2_k127_4531659_7 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000616 210.0
PYH2_k127_4531659_8 - - - - 0.0000000000000000000000000000000000000000000001022 171.0
PYH2_k127_4573408_0 Chromate Ion Transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 346.0
PYH2_k127_4573408_1 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 346.0
PYH2_k127_4573408_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000003772 209.0
PYH2_k127_4573408_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0009007 49.0
PYH2_k127_4655831_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 437.0
PYH2_k127_4655831_1 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004608 289.0
PYH2_k127_4655831_2 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001955 250.0
PYH2_k127_4655831_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000001017 112.0
PYH2_k127_4655831_4 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000001684 106.0
PYH2_k127_4655831_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000004112 91.0
PYH2_k127_4677073_0 D-amino acid K00285 - 1.4.5.1 3.593e-211 661.0
PYH2_k127_4677073_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 486.0
PYH2_k127_4677073_2 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 484.0
PYH2_k127_4677073_3 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 442.0
PYH2_k127_4677073_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000005374 263.0
PYH2_k127_4677073_5 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 256.0
PYH2_k127_4677073_6 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000001063 198.0
PYH2_k127_4677073_7 COG0112 Glycine serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000003007 167.0
PYH2_k127_4677073_8 Type II transport protein GspH K08084 - - 0.000000000000001059 87.0
PYH2_k127_4677073_9 - - - - 0.0000000000001153 83.0
PYH2_k127_4694270_0 COG4974 Site-specific recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
PYH2_k127_4694270_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 381.0
PYH2_k127_4694270_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 363.0
PYH2_k127_4694270_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 359.0
PYH2_k127_4694270_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000001075 93.0
PYH2_k127_4697839_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 603.0
PYH2_k127_4697839_1 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 468.0
PYH2_k127_4697839_2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 379.0
PYH2_k127_4697839_3 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 285.0
PYH2_k127_4697839_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000125 185.0
PYH2_k127_4697839_5 HemY protein N-terminus K02498 - - 0.000000000000000001209 90.0
PYH2_k127_4698531_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 2.57e-204 642.0
PYH2_k127_4698531_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000004316 123.0
PYH2_k127_4701949_0 protein N-acetylglucosaminyltransferase activity - - - 1.606e-228 727.0
PYH2_k127_4701949_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 606.0
PYH2_k127_4701949_10 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 264.0
PYH2_k127_4701949_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000005031 216.0
PYH2_k127_4701949_12 Phosphoglycerate mutase K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000455 203.0
PYH2_k127_4701949_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000008948 211.0
PYH2_k127_4701949_14 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000003245 197.0
PYH2_k127_4701949_15 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000008729 123.0
PYH2_k127_4701949_16 Hsp20/alpha crystallin family - - - 0.000000000000000000000000003485 116.0
PYH2_k127_4701949_17 CAAX protease self-immunity K07052 - - 0.0000000000000000000000007316 113.0
PYH2_k127_4701949_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 561.0
PYH2_k127_4701949_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 492.0
PYH2_k127_4701949_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 480.0
PYH2_k127_4701949_5 NADH:flavin oxidoreductase / NADH oxidase family K00354 - 1.6.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 472.0
PYH2_k127_4701949_6 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 395.0
PYH2_k127_4701949_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 360.0
PYH2_k127_4701949_8 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 334.0
PYH2_k127_4701949_9 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 309.0
PYH2_k127_4723743_0 Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein) - - - 1.065e-195 622.0
PYH2_k127_4723743_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 324.0
PYH2_k127_4723743_2 - - - - 0.0000000000000000000000000008992 117.0
PYH2_k127_4754469_0 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 560.0
PYH2_k127_4754469_1 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 506.0
PYH2_k127_4754469_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
PYH2_k127_4754469_3 Pfam Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 312.0
PYH2_k127_4754469_4 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000005547 155.0
PYH2_k127_4754469_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000008476 87.0
PYH2_k127_4754469_6 LysR substrate binding domain K03566 - - 0.000000003597 65.0
PYH2_k127_4760003_0 B12 binding domain K00548 - 2.1.1.13 0.0 1835.0
PYH2_k127_4760003_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 385.0
PYH2_k127_4760003_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000005188 165.0
PYH2_k127_4760003_3 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000002323 161.0
PYH2_k127_4760003_4 Protein of unknown function (DUF3567) - - - 0.000000000000000000000002859 104.0
PYH2_k127_4760003_5 Homeodomain-like domain - - - 0.00008775 46.0
PYH2_k127_4763905_0 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000108 269.0
PYH2_k127_4763905_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000233 224.0
PYH2_k127_4763905_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000006092 165.0
PYH2_k127_4763905_3 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000001103 160.0
PYH2_k127_4763905_4 Histidine kinase - - - 0.0000000000000000000001394 100.0
PYH2_k127_48200_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 583.0
PYH2_k127_48200_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 361.0
PYH2_k127_48200_2 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 329.0
PYH2_k127_48200_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 316.0
PYH2_k127_48200_4 Serine hydrolase (FSH1) K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 287.0
PYH2_k127_48200_5 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000008401 214.0
PYH2_k127_48200_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000005041 193.0
PYH2_k127_48200_7 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000004846 160.0
PYH2_k127_48200_8 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000001846 143.0
PYH2_k127_4858743_0 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 331.0
PYH2_k127_4858743_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000005198 149.0
PYH2_k127_4858743_2 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000009004 81.0
PYH2_k127_4858743_3 EamA-like transporter family K15270 - - 0.0002356 43.0
PYH2_k127_4870283_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1012.0
PYH2_k127_4870283_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.734e-225 703.0
PYH2_k127_4870283_10 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000001457 179.0
PYH2_k127_4870283_11 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000009988 169.0
PYH2_k127_4870283_12 biopolymer transport K03559 - - 0.00000000000000000000000000000000000000009141 154.0
PYH2_k127_4870283_13 Trm112p-like protein K09791 - - 0.0000000000000000000001695 98.0
PYH2_k127_4870283_14 Major Facilitator Superfamily - - - 0.00000000001811 66.0
PYH2_k127_4870283_2 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 7.494e-222 700.0
PYH2_k127_4870283_3 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.26e-214 681.0
PYH2_k127_4870283_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 369.0
PYH2_k127_4870283_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 339.0
PYH2_k127_4870283_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 311.0
PYH2_k127_4870283_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 297.0
PYH2_k127_4870283_8 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000002947 228.0
PYH2_k127_4870283_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
PYH2_k127_4878456_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 500.0
PYH2_k127_4878456_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 481.0
PYH2_k127_4878456_10 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - 0.00000000000000000007215 98.0
PYH2_k127_4878456_11 - - - - 0.000001032 53.0
PYH2_k127_4878456_12 - - - - 0.00008702 45.0
PYH2_k127_4878456_13 Type VI secretion system effector, Hcp K11903 - - 0.000801 49.0
PYH2_k127_4878456_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 485.0
PYH2_k127_4878456_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 468.0
PYH2_k127_4878456_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 397.0
PYH2_k127_4878456_5 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 311.0
PYH2_k127_4878456_6 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009109 265.0
PYH2_k127_4878456_7 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000001087 233.0
PYH2_k127_4878456_8 PFAM Secreted repeat of - - - 0.00000000000000000000000000000000000000000000000002548 182.0
PYH2_k127_4878456_9 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000001407 160.0
PYH2_k127_4887181_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.102e-224 706.0
PYH2_k127_4887181_1 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 597.0
PYH2_k127_4887181_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00002236 56.0
PYH2_k127_4947347_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 2421.0
PYH2_k127_4984134_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 426.0
PYH2_k127_4984134_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001471 260.0
PYH2_k127_4984134_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000001404 134.0
PYH2_k127_4984134_3 PFAM chemotaxis K03406,K07216 - - 0.000001654 57.0
PYH2_k127_4987448_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 427.0
PYH2_k127_4987448_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 361.0
PYH2_k127_4987448_2 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.000000000000000000000000000000000000000000000000007714 192.0
PYH2_k127_4997141_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 521.0
PYH2_k127_4997141_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 469.0
PYH2_k127_4997141_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 429.0
PYH2_k127_4997141_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 362.0
PYH2_k127_5010992_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.859e-219 687.0
PYH2_k127_5010992_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 509.0
PYH2_k127_5010992_2 Dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 510.0
PYH2_k127_5010992_3 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 396.0
PYH2_k127_5010992_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 338.0
PYH2_k127_5010992_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
PYH2_k127_5010992_6 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
PYH2_k127_5010992_7 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
PYH2_k127_5010992_8 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000001574 198.0
PYH2_k127_5014137_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1420.0
PYH2_k127_5014137_1 Peptidase family M3 K01414 - 3.4.24.70 9.638e-276 867.0
PYH2_k127_5014137_10 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000000000000007507 214.0
PYH2_k127_5014137_11 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000002562 200.0
PYH2_k127_5014137_12 Endoribonuclease L-PSP K10013 - - 0.000000000000000000000000000000000000000000000003934 177.0
PYH2_k127_5014137_13 PFAM Glutaredoxin - - - 0.00000000000000000000000000000000001757 146.0
PYH2_k127_5014137_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.0000000000000000000000000000002342 126.0
PYH2_k127_5014137_15 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000002482 108.0
PYH2_k127_5014137_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.808e-235 743.0
PYH2_k127_5014137_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 531.0
PYH2_k127_5014137_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 547.0
PYH2_k127_5014137_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 460.0
PYH2_k127_5014137_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 391.0
PYH2_k127_5014137_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 353.0
PYH2_k127_5014137_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 305.0
PYH2_k127_5014137_9 helix_turn_helix, Lux Regulon K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002462 275.0
PYH2_k127_5028776_0 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 370.0
PYH2_k127_5028776_1 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000001865 236.0
PYH2_k127_5028776_2 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000007145 207.0
PYH2_k127_5028776_3 - - - - 0.00000000000000007471 87.0
PYH2_k127_5035922_0 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 509.0
PYH2_k127_5035922_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 419.0
PYH2_k127_5035922_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 348.0
PYH2_k127_5159034_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
PYH2_k127_5159034_1 BON domain - - - 0.0000000000000000000000000000000000000000002138 169.0
PYH2_k127_5159034_2 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000002969 122.0
PYH2_k127_5159034_3 LppC putative lipoprotein K07121 - - 0.000000000000000000000009207 107.0
PYH2_k127_5159034_4 Peptidase family M48 - - - 0.000000000000000003211 87.0
PYH2_k127_5187417_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 482.0
PYH2_k127_5187417_1 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 332.0
PYH2_k127_5187417_2 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 329.0
PYH2_k127_5187417_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000002586 153.0
PYH2_k127_5187417_4 NHL repeat - - - 0.000000000000000000000000000000000002444 141.0
PYH2_k127_5187417_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000001731 122.0
PYH2_k127_5187417_6 DNA replication protein - - - 0.00000000993 61.0
PYH2_k127_518962_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 531.0
PYH2_k127_518962_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 453.0
PYH2_k127_518962_2 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000008283 186.0
PYH2_k127_5222797_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001072 221.0
PYH2_k127_5222797_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000603 195.0
PYH2_k127_5222797_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002938 138.0
PYH2_k127_5222797_3 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000121 133.0
PYH2_k127_5239006_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 1.294e-210 665.0
PYH2_k127_5239006_1 Major facilitator superfamily MFS_1 K02445 - - 0.000000000000000000000000000000000000000000000000000000002989 207.0
PYH2_k127_5286943_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.638e-201 637.0
PYH2_k127_5286943_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 556.0
PYH2_k127_5286943_10 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000001057 145.0
PYH2_k127_5286943_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001081 139.0
PYH2_k127_5286943_2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 380.0
PYH2_k127_5286943_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 372.0
PYH2_k127_5286943_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 343.0
PYH2_k127_5286943_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
PYH2_k127_5286943_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008577 247.0
PYH2_k127_5286943_7 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000009456 245.0
PYH2_k127_5286943_8 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000002093 235.0
PYH2_k127_5286943_9 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000005067 216.0
PYH2_k127_5305328_0 Glycolate oxidase subunit GlcD K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 6.131e-234 734.0
PYH2_k127_5305328_1 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 4.979e-224 703.0
PYH2_k127_5305328_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
PYH2_k127_5305328_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003026 284.0
PYH2_k127_5305328_12 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 275.0
PYH2_k127_5305328_13 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000005329 172.0
PYH2_k127_5305328_14 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000003349 161.0
PYH2_k127_5305328_15 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000001595 157.0
PYH2_k127_5305328_16 - - - - 0.000000000000000000005587 103.0
PYH2_k127_5305328_17 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000002267 84.0
PYH2_k127_5305328_18 Dodecin K09165 - - 0.000000000000000004032 87.0
PYH2_k127_5305328_19 - - - - 0.000000000000008515 75.0
PYH2_k127_5305328_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 574.0
PYH2_k127_5305328_3 AlkA N-terminal domain K13529 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 525.0
PYH2_k127_5305328_4 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 502.0
PYH2_k127_5305328_5 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 458.0
PYH2_k127_5305328_6 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 365.0
PYH2_k127_5305328_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 386.0
PYH2_k127_5305328_8 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 302.0
PYH2_k127_5305328_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 292.0
PYH2_k127_5322719_0 Bacterial protein of unknown function (DUF853) K06915 - - 6.482e-231 721.0
PYH2_k127_5322719_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
PYH2_k127_5322719_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000009257 81.0
PYH2_k127_5363567_0 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 337.0
PYH2_k127_5363567_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000002024 232.0
PYH2_k127_5366544_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 4.361e-307 953.0
PYH2_k127_5366544_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 6.403e-194 619.0
PYH2_k127_5366544_2 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 370.0
PYH2_k127_5366544_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000004001 193.0
PYH2_k127_5396876_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 6.768e-243 760.0
PYH2_k127_5396876_1 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 533.0
PYH2_k127_5396876_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 424.0
PYH2_k127_5396876_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 402.0
PYH2_k127_5396876_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 406.0
PYH2_k127_5396876_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 366.0
PYH2_k127_5396876_6 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 344.0
PYH2_k127_5396876_7 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000002261 247.0
PYH2_k127_5396876_8 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000004392 221.0
PYH2_k127_5396876_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000001791 122.0
PYH2_k127_5454414_0 MMPL family K07003 - - 0.0 1067.0
PYH2_k127_5454414_1 Protein of unknown function (DUF1302) - - - 8.21e-216 681.0
PYH2_k127_5454414_2 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001219 242.0
PYH2_k127_5456225_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1545.0
PYH2_k127_5456225_1 General function prediction only K06020 - 3.6.3.25 3.911e-291 902.0
PYH2_k127_5456225_10 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 503.0
PYH2_k127_5456225_11 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 489.0
PYH2_k127_5456225_12 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 469.0
PYH2_k127_5456225_13 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 451.0
PYH2_k127_5456225_14 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 449.0
PYH2_k127_5456225_15 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 432.0
PYH2_k127_5456225_16 PFAM PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 430.0
PYH2_k127_5456225_17 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 424.0
PYH2_k127_5456225_18 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 411.0
PYH2_k127_5456225_19 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 419.0
PYH2_k127_5456225_2 cysteine protease - - - 2.923e-236 749.0
PYH2_k127_5456225_20 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
PYH2_k127_5456225_21 AMP-binding enzyme C-terminal domain K16029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 370.0
PYH2_k127_5456225_22 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
PYH2_k127_5456225_23 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 314.0
PYH2_k127_5456225_24 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 285.0
PYH2_k127_5456225_25 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000001615 229.0
PYH2_k127_5456225_26 - - - - 0.0000000000000000000000000000000000000000000000000000000001125 209.0
PYH2_k127_5456225_27 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000001365 189.0
PYH2_k127_5456225_28 amidase activity - - - 0.000000000000000000000000000000000000000000000000001701 186.0
PYH2_k127_5456225_29 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.000000000000000000000000000000000000000000000003774 179.0
PYH2_k127_5456225_3 L-serine dehydratase K01752 - 4.3.1.17 7.981e-228 715.0
PYH2_k127_5456225_30 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000001146 182.0
PYH2_k127_5456225_32 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000001949 134.0
PYH2_k127_5456225_33 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000006961 134.0
PYH2_k127_5456225_34 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000003534 126.0
PYH2_k127_5456225_35 - - - - 0.00000000000000000000000000003511 122.0
PYH2_k127_5456225_36 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001252 110.0
PYH2_k127_5456225_37 peptidoglycan-binding protein, lysm - - - 0.0000000000000000006789 88.0
PYH2_k127_5456225_38 Protein of unknown function (DUF2877) - - - 0.00000000000000002306 93.0
PYH2_k127_5456225_39 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000002775 84.0
PYH2_k127_5456225_4 PERMEase K06901 - - 1.661e-225 710.0
PYH2_k127_5456225_5 ABC-type dipeptide transport system periplasmic component K02035 - - 1.265e-220 694.0
PYH2_k127_5456225_6 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 617.0
PYH2_k127_5456225_7 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 586.0
PYH2_k127_5456225_8 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 513.0
PYH2_k127_5456225_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 502.0
PYH2_k127_5478374_0 4Fe-4S dicluster domain K18930 - - 0.0 1162.0
PYH2_k127_5478374_1 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.44e-236 746.0
PYH2_k127_5478374_10 - - - - 0.000000000000000000003137 101.0
PYH2_k127_5478374_11 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000431 72.0
PYH2_k127_5478374_12 Protein of unknown function (DUF1439) - - - 0.0001824 51.0
PYH2_k127_5478374_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 531.0
PYH2_k127_5478374_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 439.0
PYH2_k127_5478374_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 427.0
PYH2_k127_5478374_5 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 317.0
PYH2_k127_5478374_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 331.0
PYH2_k127_5478374_7 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
PYH2_k127_5478374_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000003611 198.0
PYH2_k127_5504868_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 1.781e-233 736.0
PYH2_k127_5504868_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.552e-194 614.0
PYH2_k127_5504868_2 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 564.0
PYH2_k127_5504868_3 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 353.0
PYH2_k127_5504868_4 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
PYH2_k127_5504868_5 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 294.0
PYH2_k127_5504868_6 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
PYH2_k127_5537309_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1185.0
PYH2_k127_5537309_1 Periplasmic binding protein K01999 - - 7.245e-206 652.0
PYH2_k127_5537309_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000004659 119.0
PYH2_k127_5537309_2 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 539.0
PYH2_k127_5537309_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 427.0
PYH2_k127_5537309_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 423.0
PYH2_k127_5537309_5 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 418.0
PYH2_k127_5537309_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 403.0
PYH2_k127_5537309_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
PYH2_k127_5537309_8 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000009944 263.0
PYH2_k127_5537309_9 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004648 253.0
PYH2_k127_5591442_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1197.0
PYH2_k127_5591442_1 Elongation factor G, domain IV K02355 - - 6.339e-309 960.0
PYH2_k127_5591442_10 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 451.0
PYH2_k127_5591442_11 ABC-type multidrug transport system, ATPase K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 402.0
PYH2_k127_5591442_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 395.0
PYH2_k127_5591442_13 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
PYH2_k127_5591442_14 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 340.0
PYH2_k127_5591442_15 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 315.0
PYH2_k127_5591442_16 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 300.0
PYH2_k127_5591442_17 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 287.0
PYH2_k127_5591442_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
PYH2_k127_5591442_19 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
PYH2_k127_5591442_2 Aldehyde dehydrogenase family - - - 4.427e-215 675.0
PYH2_k127_5591442_20 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001007 246.0
PYH2_k127_5591442_21 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.0000000000000000000000000000001221 129.0
PYH2_k127_5591442_22 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000948 88.0
PYH2_k127_5591442_23 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000002213 55.0
PYH2_k127_5591442_3 permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 612.0
PYH2_k127_5591442_4 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 593.0
PYH2_k127_5591442_5 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 584.0
PYH2_k127_5591442_6 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 559.0
PYH2_k127_5591442_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 517.0
PYH2_k127_5591442_8 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 471.0
PYH2_k127_5591442_9 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 458.0
PYH2_k127_5623559_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.255e-308 959.0
PYH2_k127_5623559_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.281e-296 917.0
PYH2_k127_5623559_10 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 304.0
PYH2_k127_5623559_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002997 259.0
PYH2_k127_5623559_12 Cytochrome K08738 - - 0.0000000000000000000000000000000001504 135.0
PYH2_k127_5623559_13 - - - - 0.00000004452 57.0
PYH2_k127_5623559_2 AMP-binding enzyme C-terminal domain K18661 - - 1.257e-223 704.0
PYH2_k127_5623559_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 475.0
PYH2_k127_5623559_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 464.0
PYH2_k127_5623559_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 457.0
PYH2_k127_5623559_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 441.0
PYH2_k127_5623559_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 396.0
PYH2_k127_5623559_8 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 393.0
PYH2_k127_5623559_9 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 355.0
PYH2_k127_5630000_0 - - - - 0.0 1392.0
PYH2_k127_5630000_1 Amidohydrolase family - - - 0.000000000000193 72.0
PYH2_k127_5637816_0 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 6.512e-247 771.0
PYH2_k127_5637816_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 6.434e-246 768.0
PYH2_k127_5637816_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000000000004178 202.0
PYH2_k127_5637816_3 Formate dehydrogenase gamma subunit K00127 - - 0.00000000000000000000000000000000000000000000002405 179.0
PYH2_k127_5637816_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000008315 80.0
PYH2_k127_5653500_0 Ammonium Transporter Family K03320,K06580 - - 8.308e-219 685.0
PYH2_k127_5653500_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 508.0
PYH2_k127_5653500_2 PFAM MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 426.0
PYH2_k127_5653500_3 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000000132 231.0
PYH2_k127_5653500_4 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006752 204.0
PYH2_k127_5653500_5 Cytochrome c K17223 - - 0.00000000000000000000038 109.0
PYH2_k127_5660935_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 2.445e-257 801.0
PYH2_k127_5660935_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 351.0
PYH2_k127_5660935_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 301.0
PYH2_k127_5660935_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 310.0
PYH2_k127_5660935_4 Ankyrin repeats (3 copies) K06867,K21440 - - 0.0000000000000000000000000000000000000000000000001688 184.0
PYH2_k127_5660935_5 - - - - 0.0000000000000000000000000000000000000001163 160.0
PYH2_k127_5660935_6 PQQ enzyme repeat - - - 0.000000000000000000000000000000168 129.0
PYH2_k127_5685288_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 497.0
PYH2_k127_5685288_1 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001257 241.0
PYH2_k127_5685288_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.00000000000000000000000008904 115.0
PYH2_k127_5685288_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000002065 94.0
PYH2_k127_5686915_0 o-acetylhomoserine K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 548.0
PYH2_k127_5686915_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 267.0
PYH2_k127_5686915_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
PYH2_k127_5686915_3 Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
PYH2_k127_5686915_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000001059 179.0
PYH2_k127_5698268_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 7.722e-304 951.0
PYH2_k127_5698268_1 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 493.0
PYH2_k127_5698268_2 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000004102 106.0
PYH2_k127_5704598_0 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 471.0
PYH2_k127_5704598_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001573 208.0
PYH2_k127_5704598_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000001608 96.0
PYH2_k127_5704598_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000004489 87.0
PYH2_k127_5735548_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
PYH2_k127_5735548_1 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000003137 162.0
PYH2_k127_5735548_2 HIUase/Transthyretin family K07127 - 3.5.2.17 0.0000000000000000000000000000000001048 136.0
PYH2_k127_5735548_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000002115 128.0
PYH2_k127_5767288_0 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
PYH2_k127_5767288_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000004488 138.0
PYH2_k127_5767288_2 PFAM Peptidase family M23 - - - 0.0000000000000000004721 87.0
PYH2_k127_5770288_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 595.0
PYH2_k127_5770288_1 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 597.0
PYH2_k127_5770288_2 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 300.0
PYH2_k127_5770288_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000001285 193.0
PYH2_k127_5770288_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000008089 104.0
PYH2_k127_5795852_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1662.0
PYH2_k127_5795852_1 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 442.0
PYH2_k127_5795852_2 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 341.0
PYH2_k127_5795852_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000001904 204.0
PYH2_k127_5795852_4 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000008044 159.0
PYH2_k127_5795852_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000009582 115.0
PYH2_k127_5795852_6 - - - - 0.0000000000000000000272 98.0
PYH2_k127_5795852_7 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000002042 64.0
PYH2_k127_5795852_8 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000001054 55.0
PYH2_k127_5795852_9 - - - - 0.000006674 50.0
PYH2_k127_5814943_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002882 271.0
PYH2_k127_5814943_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002444 198.0
PYH2_k127_5814943_2 Protein of unknown function (DUF1445) - - - 0.0000000000000000001603 88.0
PYH2_k127_5836940_0 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 384.0
PYH2_k127_5836940_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 307.0
PYH2_k127_5836940_10 Domain of unknown function (DUF1992) - - - 0.00000000000000000000002925 105.0
PYH2_k127_5836940_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 294.0
PYH2_k127_5836940_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 289.0
PYH2_k127_5836940_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000006991 208.0
PYH2_k127_5836940_5 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000001795 178.0
PYH2_k127_5836940_6 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000002991 161.0
PYH2_k127_5836940_7 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000001169 150.0
PYH2_k127_5836940_8 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000006218 141.0
PYH2_k127_5836940_9 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000009631 134.0
PYH2_k127_5858061_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0 1003.0
PYH2_k127_5858061_1 peptidase dimerisation domain protein - - - 2.053e-209 657.0
PYH2_k127_5858061_2 deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 590.0
PYH2_k127_5858061_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 499.0
PYH2_k127_5858061_4 Nucleoside-binding outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000001195 226.0
PYH2_k127_5858061_5 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000002168 186.0
PYH2_k127_5858061_6 FCD - - - 0.000000000000000000000000000000000000000000000008147 181.0
PYH2_k127_5858061_7 Family of unknown function (DUF5329) - - - 0.000000000000000000000000000000000002478 142.0
PYH2_k127_5858061_8 s cog2930 - - - 0.000000000000001004 77.0
PYH2_k127_5887040_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 595.0
PYH2_k127_5887040_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000008534 216.0
PYH2_k127_5897919_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002013 278.0
PYH2_k127_5897919_1 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000002209 213.0
PYH2_k127_5897919_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000008197 155.0
PYH2_k127_5900731_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
PYH2_k127_5900731_1 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002823 278.0
PYH2_k127_5900731_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.00000000002181 68.0
PYH2_k127_5903460_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 9.542e-297 937.0
PYH2_k127_5903460_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.021e-202 658.0
PYH2_k127_5903460_2 TRAP dicarboxylate transporter, DctM subunit K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 439.0
PYH2_k127_5903460_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 314.0
PYH2_k127_5903460_4 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004313 263.0
PYH2_k127_5903460_5 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007769 267.0
PYH2_k127_5903460_6 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001198 241.0
PYH2_k127_5951733_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 450.0
PYH2_k127_5951733_1 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000211 230.0
PYH2_k127_5966399_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 554.0
PYH2_k127_5966399_1 Trypsin K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 476.0
PYH2_k127_5966399_2 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
PYH2_k127_5966399_3 tetR family - - - 0.0000000000000000000000000000000000000000000000000000002002 202.0
PYH2_k127_5966399_4 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000003524 147.0
PYH2_k127_5985601_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1348.0
PYH2_k127_5985601_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 566.0
PYH2_k127_5985601_2 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 426.0
PYH2_k127_5985601_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000005776 133.0
PYH2_k127_5985601_4 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000002319 113.0
PYH2_k127_6007160_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.7e-322 1002.0
PYH2_k127_6007160_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.084e-311 966.0
PYH2_k127_6007160_10 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 487.0
PYH2_k127_6007160_11 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 469.0
PYH2_k127_6007160_12 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 389.0
PYH2_k127_6007160_13 transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 352.0
PYH2_k127_6007160_14 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 353.0
PYH2_k127_6007160_15 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 342.0
PYH2_k127_6007160_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 313.0
PYH2_k127_6007160_17 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
PYH2_k127_6007160_18 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
PYH2_k127_6007160_19 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
PYH2_k127_6007160_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 8.093e-302 935.0
PYH2_k127_6007160_20 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000001659 212.0
PYH2_k127_6007160_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000005754 159.0
PYH2_k127_6007160_22 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000006137 154.0
PYH2_k127_6007160_23 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000007452 143.0
PYH2_k127_6007160_24 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000005561 127.0
PYH2_k127_6007160_25 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000008787 109.0
PYH2_k127_6007160_26 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000002353 61.0
PYH2_k127_6007160_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.041e-280 871.0
PYH2_k127_6007160_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.276e-245 766.0
PYH2_k127_6007160_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.868e-242 751.0
PYH2_k127_6007160_6 SAF - - - 8.482e-210 661.0
PYH2_k127_6007160_7 Methionine gamma-lyase K01761 - 4.4.1.11 2.179e-209 660.0
PYH2_k127_6007160_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 575.0
PYH2_k127_6007160_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 549.0
PYH2_k127_6055369_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.805e-272 846.0
PYH2_k127_6055369_1 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.564e-252 784.0
PYH2_k127_6055369_2 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 2.755e-212 666.0
PYH2_k127_6055369_3 Aldehyde dehydrogenase family K15514 - 1.2.1.77 3.539e-206 654.0
PYH2_k127_6055369_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 385.0
PYH2_k127_6066520_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 9.335e-231 724.0
PYH2_k127_6066520_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
PYH2_k127_6066520_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000001179 216.0
PYH2_k127_6066520_3 Methyltransferase - - - 0.00001881 53.0
PYH2_k127_6077134_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.072e-272 851.0
PYH2_k127_6077134_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.761e-250 779.0
PYH2_k127_6077134_10 protein conserved in bacteria - - - 0.00000000000000192 82.0
PYH2_k127_6077134_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 447.0
PYH2_k127_6077134_3 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 381.0
PYH2_k127_6077134_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 333.0
PYH2_k127_6077134_5 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
PYH2_k127_6077134_6 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000008729 200.0
PYH2_k127_6077134_7 spore germination - - - 0.00000000000000000000000000000000000000000000000000001151 200.0
PYH2_k127_6077134_8 hydrogenase maturation protease - - - 0.000000000000000000000000000000000006104 145.0
PYH2_k127_6077134_9 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000009198 112.0
PYH2_k127_6137002_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 578.0
PYH2_k127_6137002_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 367.0
PYH2_k127_6193808_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 1.434e-276 874.0
PYH2_k127_6193808_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 6.451e-240 747.0
PYH2_k127_6193808_10 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 383.0
PYH2_k127_6193808_11 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 354.0
PYH2_k127_6193808_12 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 328.0
PYH2_k127_6193808_13 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 337.0
PYH2_k127_6193808_14 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 320.0
PYH2_k127_6193808_15 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005226 254.0
PYH2_k127_6193808_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001136 214.0
PYH2_k127_6193808_17 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000219 194.0
PYH2_k127_6193808_18 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000006219 190.0
PYH2_k127_6193808_19 enzyme binding - - - 0.000000000000000000000000000005322 124.0
PYH2_k127_6193808_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 6.576e-226 702.0
PYH2_k127_6193808_20 Dodecin K09165 - - 0.00000000000000000000000000004411 118.0
PYH2_k127_6193808_21 - - - - 0.0003865 49.0
PYH2_k127_6193808_3 MmgE PrpD family protein - - - 3.495e-206 650.0
PYH2_k127_6193808_4 CoA-transferase family III K18289 - 2.8.3.22 8.656e-196 618.0
PYH2_k127_6193808_5 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 585.0
PYH2_k127_6193808_6 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 580.0
PYH2_k127_6193808_7 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 557.0
PYH2_k127_6193808_8 periplasmic K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 481.0
PYH2_k127_6193808_9 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 406.0
PYH2_k127_619644_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 395.0
PYH2_k127_619644_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 385.0
PYH2_k127_619644_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 378.0
PYH2_k127_619644_3 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000001799 199.0
PYH2_k127_619644_4 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000002793 190.0
PYH2_k127_619644_5 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000001611 192.0
PYH2_k127_6228324_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1322.0
PYH2_k127_6228324_1 Domain of unknown function (DUF5117) - - - 3.64e-213 696.0
PYH2_k127_6228324_2 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003879 266.0
PYH2_k127_6289895_0 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 401.0
PYH2_k127_6289895_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 284.0
PYH2_k127_6289895_2 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 276.0
PYH2_k127_6289895_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000007862 181.0
PYH2_k127_6289895_4 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.0000000000000000000000000000000000000001559 154.0
PYH2_k127_6331204_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1579.0
PYH2_k127_6331204_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.291e-261 823.0
PYH2_k127_6331204_10 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
PYH2_k127_6331204_11 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 300.0
PYH2_k127_6331204_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 299.0
PYH2_k127_6331204_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 308.0
PYH2_k127_6331204_14 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000002142 233.0
PYH2_k127_6331204_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000008073 214.0
PYH2_k127_6331204_16 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000000000000000000003988 201.0
PYH2_k127_6331204_17 glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000576 189.0
PYH2_k127_6331204_18 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000001173 173.0
PYH2_k127_6331204_19 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000002736 161.0
PYH2_k127_6331204_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.613e-228 710.0
PYH2_k127_6331204_20 Ferredoxin K05337 - - 0.0000000000000000000000000000000004418 133.0
PYH2_k127_6331204_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000006658 121.0
PYH2_k127_6331204_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000005248 113.0
PYH2_k127_6331204_23 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000003573 111.0
PYH2_k127_6331204_3 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.752e-209 663.0
PYH2_k127_6331204_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.765e-203 648.0
PYH2_k127_6331204_5 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 587.0
PYH2_k127_6331204_6 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 571.0
PYH2_k127_6331204_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 563.0
PYH2_k127_6331204_8 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 499.0
PYH2_k127_6331204_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 475.0
PYH2_k127_63325_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 343.0
PYH2_k127_63325_1 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000000000007826 241.0
PYH2_k127_63325_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000001173 217.0
PYH2_k127_63325_3 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.000000000000000000000000000000001059 136.0
PYH2_k127_63325_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000001207 119.0
PYH2_k127_6361850_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 496.0
PYH2_k127_6361850_1 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 337.0
PYH2_k127_6394798_0 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000002334 189.0
PYH2_k127_6394798_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000004651 171.0
PYH2_k127_6394798_2 calcium-dependent cysteine-type endopeptidase activity K08578,K08585 - - 0.0001557 54.0
PYH2_k127_6394855_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 352.0
PYH2_k127_6394855_1 Domain of unknown function (DUF4347) - - - 0.0000001274 62.0
PYH2_k127_6397771_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1016.0
PYH2_k127_6397771_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 475.0
PYH2_k127_6397771_2 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 479.0
PYH2_k127_6397771_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 388.0
PYH2_k127_6397771_4 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 385.0
PYH2_k127_6397771_5 phosphocarrier protein HPr K11189 - - 0.0000000000000000005672 90.0
PYH2_k127_6408629_0 FtsX-like permease family K02004 - - 1.147e-237 752.0
PYH2_k127_6408629_1 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000007105 191.0
PYH2_k127_6408629_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000006413 154.0
PYH2_k127_6465822_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 5.717e-271 847.0
PYH2_k127_6465822_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 1.349e-223 708.0
PYH2_k127_6465822_10 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001326 276.0
PYH2_k127_6465822_11 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000001297 186.0
PYH2_k127_6465822_12 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000006989 188.0
PYH2_k127_6465822_13 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000002928 178.0
PYH2_k127_6465822_14 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000002142 181.0
PYH2_k127_6465822_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000000006205 148.0
PYH2_k127_6465822_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001768 147.0
PYH2_k127_6465822_17 ASCH - - - 0.0000000000000000000000000000001377 129.0
PYH2_k127_6465822_19 DnaJ domain protein - - - 0.0000009869 57.0
PYH2_k127_6465822_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 2.136e-223 707.0
PYH2_k127_6465822_3 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 8.08e-217 677.0
PYH2_k127_6465822_4 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 493.0
PYH2_k127_6465822_5 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 436.0
PYH2_k127_6465822_6 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 409.0
PYH2_k127_6465822_7 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 400.0
PYH2_k127_6465822_8 threonine dehydratase K17989 GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 372.0
PYH2_k127_6465822_9 Protein conserved in bacteria K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 342.0
PYH2_k127_6474179_1 Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000464 112.0
PYH2_k127_6483217_0 Histidine kinase K02487,K06596 - - 0.0 1248.0
PYH2_k127_6483217_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.331e-288 891.0
PYH2_k127_6483217_10 PFAM Type II secretion system protein E K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 500.0
PYH2_k127_6483217_11 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 497.0
PYH2_k127_6483217_12 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 470.0
PYH2_k127_6483217_13 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 462.0
PYH2_k127_6483217_14 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 449.0
PYH2_k127_6483217_15 Pfam Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 438.0
PYH2_k127_6483217_16 TIGRFAM rfaE bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 400.0
PYH2_k127_6483217_17 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 394.0
PYH2_k127_6483217_18 Glycosyl transferase, family 2 K07011,K13005 - 2.4.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 378.0
PYH2_k127_6483217_19 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 355.0
PYH2_k127_6483217_2 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 3.339e-209 658.0
PYH2_k127_6483217_20 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 336.0
PYH2_k127_6483217_21 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 326.0
PYH2_k127_6483217_22 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 322.0
PYH2_k127_6483217_23 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 314.0
PYH2_k127_6483217_25 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 301.0
PYH2_k127_6483217_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003683 284.0
PYH2_k127_6483217_27 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008929 277.0
PYH2_k127_6483217_28 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003813 275.0
PYH2_k127_6483217_29 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
PYH2_k127_6483217_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 1.461e-201 640.0
PYH2_k127_6483217_30 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 260.0
PYH2_k127_6483217_31 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
PYH2_k127_6483217_32 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000009257 224.0
PYH2_k127_6483217_33 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000001058 227.0
PYH2_k127_6483217_34 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000006138 231.0
PYH2_k127_6483217_35 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
PYH2_k127_6483217_36 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000003698 213.0
PYH2_k127_6483217_37 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000003458 214.0
PYH2_k127_6483217_38 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000006433 211.0
PYH2_k127_6483217_39 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000363 197.0
PYH2_k127_6483217_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 591.0
PYH2_k127_6483217_40 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000001034 186.0
PYH2_k127_6483217_41 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000804 173.0
PYH2_k127_6483217_42 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000002433 175.0
PYH2_k127_6483217_43 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000001661 143.0
PYH2_k127_6483217_44 protein methyltransferase activity - - - 0.00000000000000000000000000000000002206 147.0
PYH2_k127_6483217_45 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000003503 123.0
PYH2_k127_6483217_46 CheW-like domain K02659 - - 0.000000000000000000000000000006916 125.0
PYH2_k127_6483217_47 Type II/IV secretion system protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000128 61.0
PYH2_k127_6483217_48 CRISPR_assoc - - - 0.00000778 57.0
PYH2_k127_6483217_5 Putative zinc binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 581.0
PYH2_k127_6483217_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 570.0
PYH2_k127_6483217_7 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 539.0
PYH2_k127_6483217_8 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 516.0
PYH2_k127_6483217_9 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 524.0
PYH2_k127_6539069_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 442.0
PYH2_k127_6539069_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000006077 201.0
PYH2_k127_6539069_2 PFAM Prolyl oligopeptidase family - - - 0.000002897 49.0
PYH2_k127_6540527_0 receptor K02014 - - 1.574e-320 1006.0
PYH2_k127_6540527_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 3.581e-237 746.0
PYH2_k127_6540527_10 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
PYH2_k127_6540527_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 357.0
PYH2_k127_6540527_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
PYH2_k127_6540527_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002939 271.0
PYH2_k127_6540527_14 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
PYH2_k127_6540527_15 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000007456 211.0
PYH2_k127_6540527_16 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000003767 208.0
PYH2_k127_6540527_17 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000005286 215.0
PYH2_k127_6540527_18 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000006194 204.0
PYH2_k127_6540527_19 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000005787 190.0
PYH2_k127_6540527_2 TonB dependent receptor - - - 2.969e-224 728.0
PYH2_k127_6540527_20 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000004499 160.0
PYH2_k127_6540527_21 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000002511 148.0
PYH2_k127_6540527_22 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000005248 136.0
PYH2_k127_6540527_23 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000000000000174 103.0
PYH2_k127_6540527_24 - - - - 0.0000000000000000232 87.0
PYH2_k127_6540527_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 614.0
PYH2_k127_6540527_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 565.0
PYH2_k127_6540527_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 531.0
PYH2_k127_6540527_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 469.0
PYH2_k127_6540527_7 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 466.0
PYH2_k127_6540527_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 449.0
PYH2_k127_6540527_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 377.0
PYH2_k127_6557883_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 3.28e-318 988.0
PYH2_k127_6557883_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 313.0
PYH2_k127_6557883_2 - - - - 0.00000000000000000000000000000000000000000006127 164.0
PYH2_k127_6557883_3 - - - - 0.0000000000000000000000000002122 121.0
PYH2_k127_6557883_4 Protein of unknown function (DUF2933) - - - 0.000000000000000001135 88.0
PYH2_k127_6557883_5 - - - - 0.0000000000000009189 80.0
PYH2_k127_657651_0 Transketolase, C-terminal domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 492.0
PYH2_k127_657651_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 464.0
PYH2_k127_657651_2 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 454.0
PYH2_k127_657651_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000002449 225.0
PYH2_k127_657651_4 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000004474 166.0
PYH2_k127_657651_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000005552 138.0
PYH2_k127_657651_6 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000906 129.0
PYH2_k127_657651_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000006944 106.0
PYH2_k127_657651_8 Phosphopantetheine attachment site - - - 0.0000000000000001403 92.0
PYH2_k127_6585215_0 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000003293 164.0
PYH2_k127_6585215_1 - - - - 0.000000000000003992 76.0
PYH2_k127_6620621_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.067e-273 859.0
PYH2_k127_6649195_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 4.443e-312 967.0
PYH2_k127_6649195_1 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000003544 153.0
PYH2_k127_6649195_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000009965 140.0
PYH2_k127_6649195_3 Cytochrome c K08738 - - 0.0000000000000000000000000000004045 124.0
PYH2_k127_6649195_4 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000001557 94.0
PYH2_k127_6649195_5 receptor K16087,K16089 - - 0.0000000001381 62.0
PYH2_k127_6660200_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.542e-223 702.0
PYH2_k127_6660200_1 Tim44 - - - 0.00000000000000000000000000000000000000000000003485 178.0
PYH2_k127_6660200_2 - - - - 0.0000000000000000000000001967 116.0
PYH2_k127_6660200_3 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000004816 106.0
PYH2_k127_6660200_4 PFAM Sterol-binding domain protein K03690 - - 0.000004617 50.0
PYH2_k127_6665991_0 PFAM ABC transporter related K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 481.0
PYH2_k127_6665991_1 Secretin N-terminal domain K02453,K12282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 413.0
PYH2_k127_6665991_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 386.0
PYH2_k127_6665991_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 377.0
PYH2_k127_6665991_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 372.0
PYH2_k127_6665991_5 Transport permease protein K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 294.0
PYH2_k127_6665991_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002631 250.0
PYH2_k127_6665991_7 Kdo2-lipid A biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000006211 246.0
PYH2_k127_6665991_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001301 202.0
PYH2_k127_6665991_9 - - - - 0.000000000000000000001639 100.0
PYH2_k127_6672473_0 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 503.0
PYH2_k127_6672473_1 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 343.0
PYH2_k127_6672473_2 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000004129 175.0
PYH2_k127_6672473_3 LysR substrate binding domain - - - 0.0000004035 52.0
PYH2_k127_6735389_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 589.0
PYH2_k127_6735389_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007044 231.0
PYH2_k127_6735389_3 PFAM Transposase IS200 like - - - 0.000000000003169 68.0
PYH2_k127_6752115_0 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
PYH2_k127_6752115_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 348.0
PYH2_k127_6752115_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 320.0
PYH2_k127_6752115_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000792 246.0
PYH2_k127_6752115_4 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000000000006401 169.0
PYH2_k127_6752115_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000003102 143.0
PYH2_k127_6752115_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000003275 102.0
PYH2_k127_6752115_7 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000000000004277 101.0
PYH2_k127_6752115_8 Bacterial Ig-like domain 2 - - - 0.000000005518 64.0
PYH2_k127_6756051_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 545.0
PYH2_k127_6756051_1 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
PYH2_k127_6756051_2 Transposase - - - 0.0000000000000000000000000446 114.0
PYH2_k127_6756051_3 DDE superfamily endonuclease - - - 0.0000000000000000000007466 102.0
PYH2_k127_6765841_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 531.0
PYH2_k127_6765841_1 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 502.0
PYH2_k127_6765841_10 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000006559 81.0
PYH2_k127_6765841_2 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 436.0
PYH2_k127_6765841_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 399.0
PYH2_k127_6765841_4 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 377.0
PYH2_k127_6765841_5 Periplasmic sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 343.0
PYH2_k127_6765841_6 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 317.0
PYH2_k127_6765841_7 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
PYH2_k127_6765841_8 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000000963 128.0
PYH2_k127_6765841_9 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000002801 94.0
PYH2_k127_6785992_0 oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 426.0
PYH2_k127_6785992_1 Glycine cleavage H-protein - - - 0.000000000000000000000003929 108.0
PYH2_k127_6785992_2 DsrE/DsrF-like family - - - 0.0000000000002572 79.0
PYH2_k127_6801693_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.662e-221 697.0
PYH2_k127_6801693_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 584.0
PYH2_k127_6801693_2 N-acyl-D-aspartate D-glutamate deacylase K06015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 537.0
PYH2_k127_6801693_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 436.0
PYH2_k127_6801693_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
PYH2_k127_6801693_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 296.0
PYH2_k127_6801693_6 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000003271 217.0
PYH2_k127_6802847_0 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 456.0
PYH2_k127_6802847_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
PYH2_k127_6802847_2 Major facilitator superfamily K07552,K18552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 336.0
PYH2_k127_6802847_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 273.0
PYH2_k127_6802847_4 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000003694 233.0
PYH2_k127_6802847_5 similarity to GP 3192745 - - - 0.0000000000000000000000000002069 117.0
PYH2_k127_682019_0 type VI secretion protein K11891 - - 2.399e-246 784.0
PYH2_k127_682019_1 type VI secretion protein K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 475.0
PYH2_k127_682019_2 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 453.0
PYH2_k127_682019_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001601 267.0
PYH2_k127_682019_4 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.000000000000000000000000000004484 129.0
PYH2_k127_6858867_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 6.24e-260 807.0
PYH2_k127_6858867_1 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 585.0
PYH2_k127_6858867_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 540.0
PYH2_k127_6858867_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 498.0
PYH2_k127_6858867_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 473.0
PYH2_k127_6858867_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 386.0
PYH2_k127_6858867_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000002508 238.0
PYH2_k127_6858867_7 Cysteine synthase K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000001434 152.0
PYH2_k127_6858867_8 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000008379 74.0
PYH2_k127_6862728_0 Flavin containing amine oxidoreductase K06955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 475.0
PYH2_k127_6862728_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006721 283.0
PYH2_k127_6862728_2 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005504 265.0
PYH2_k127_6862728_3 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003416 243.0
PYH2_k127_6862728_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000002259 220.0
PYH2_k127_6862728_5 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000008813 176.0
PYH2_k127_6862728_6 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000000000000000003388 128.0
PYH2_k127_6862728_7 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000009062 123.0
PYH2_k127_6862728_8 - - - - 0.00000000000000000007748 95.0
PYH2_k127_6862728_9 - - - - 0.000000000000000003588 85.0
PYH2_k127_6873186_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1312.0
PYH2_k127_6873186_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1264.0
PYH2_k127_6873186_10 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000003571 204.0
PYH2_k127_6873186_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000001525 160.0
PYH2_k127_6873186_12 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000004473 161.0
PYH2_k127_6873186_13 Cold shock protein K03704 - - 0.0000000000000000000000000000000003239 134.0
PYH2_k127_6873186_14 Cytochrome c, class I - - - 0.000000000000000000001975 100.0
PYH2_k127_6873186_15 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000003964 93.0
PYH2_k127_6873186_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000002624 66.0
PYH2_k127_6873186_2 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 9.656e-236 733.0
PYH2_k127_6873186_3 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 501.0
PYH2_k127_6873186_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 482.0
PYH2_k127_6873186_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 398.0
PYH2_k127_6873186_6 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
PYH2_k127_6873186_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000001006 237.0
PYH2_k127_6873186_8 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000003586 237.0
PYH2_k127_6873186_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000002253 224.0
PYH2_k127_6901813_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 580.0
PYH2_k127_6901813_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 568.0
PYH2_k127_6901813_2 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 319.0
PYH2_k127_6901813_3 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 310.0
PYH2_k127_6901813_4 Transcriptional regulator K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 306.0
PYH2_k127_6901813_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001499 280.0
PYH2_k127_6901813_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000398 171.0
PYH2_k127_6901813_7 Protein of unknown function (DUF2783) - - - 0.0000000000000002826 81.0
PYH2_k127_6901813_9 - - - - 0.0005322 47.0
PYH2_k127_6909264_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 569.0
PYH2_k127_6909264_1 - - - - 0.000000000000000009011 85.0
PYH2_k127_6909264_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000003311 63.0
PYH2_k127_693210_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 597.0
PYH2_k127_693210_1 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 480.0
PYH2_k127_693210_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 479.0
PYH2_k127_693210_3 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000001633 184.0
PYH2_k127_693210_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000004754 62.0
PYH2_k127_6940954_0 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 475.0
PYH2_k127_6940954_1 DJ-1/PfpI family - - - 0.0000000000001032 72.0
PYH2_k127_6952283_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1394.0
PYH2_k127_6952283_1 Large family of predicted nucleotide-binding domains K07175 - - 9.62e-243 760.0
PYH2_k127_6952283_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 314.0
PYH2_k127_6952283_11 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003511 284.0
PYH2_k127_6952283_12 PFAM Fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
PYH2_k127_6952283_13 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003166 270.0
PYH2_k127_6952283_14 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001208 241.0
PYH2_k127_6952283_15 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
PYH2_k127_6952283_16 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000002303 211.0
PYH2_k127_6952283_17 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000006176 205.0
PYH2_k127_6952283_18 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000005087 192.0
PYH2_k127_6952283_19 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000007755 186.0
PYH2_k127_6952283_2 Aminotransferase K14261 - - 6.467e-227 707.0
PYH2_k127_6952283_20 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000000007853 184.0
PYH2_k127_6952283_21 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000004158 150.0
PYH2_k127_6952283_22 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000006895 147.0
PYH2_k127_6952283_23 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000008714 149.0
PYH2_k127_6952283_24 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000007138 89.0
PYH2_k127_6952283_25 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000007473 98.0
PYH2_k127_6952283_26 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000003055 90.0
PYH2_k127_6952283_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.642e-218 685.0
PYH2_k127_6952283_4 homoserine dehydrogenase K00003 - 1.1.1.3 2.309e-199 629.0
PYH2_k127_6952283_5 Threonine synthase K01733 - 4.2.3.1 6.141e-194 619.0
PYH2_k127_6952283_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 519.0
PYH2_k127_6952283_7 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 494.0
PYH2_k127_6952283_8 JmjC domain, hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 477.0
PYH2_k127_6952283_9 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 331.0
PYH2_k127_6956525_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1715.0
PYH2_k127_6956525_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3e-323 998.0
PYH2_k127_6956525_10 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 446.0
PYH2_k127_6956525_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 437.0
PYH2_k127_6956525_12 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 426.0
PYH2_k127_6956525_13 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 407.0
PYH2_k127_6956525_14 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 367.0
PYH2_k127_6956525_15 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 309.0
PYH2_k127_6956525_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001463 284.0
PYH2_k127_6956525_17 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001913 285.0
PYH2_k127_6956525_18 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001684 267.0
PYH2_k127_6956525_19 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001974 254.0
PYH2_k127_6956525_2 CoA-transferase family III K07749 - 2.8.3.16 3.202e-201 635.0
PYH2_k127_6956525_20 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000002182 228.0
PYH2_k127_6956525_21 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000003094 213.0
PYH2_k127_6956525_22 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000001538 187.0
PYH2_k127_6956525_23 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000002275 199.0
PYH2_k127_6956525_24 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000011 181.0
PYH2_k127_6956525_25 membrane - - - 0.0000000000000000000000000000000000035 141.0
PYH2_k127_6956525_26 CRS1_YhbY K07574 - - 0.000000000000000000000000000000001666 134.0
PYH2_k127_6956525_27 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000009303 125.0
PYH2_k127_6956525_28 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000933 133.0
PYH2_k127_6956525_29 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000006971 130.0
PYH2_k127_6956525_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 615.0
PYH2_k127_6956525_4 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 579.0
PYH2_k127_6956525_5 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 510.0
PYH2_k127_6956525_6 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 503.0
PYH2_k127_6956525_7 NMT1-like family K02051,K15576,K22067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 498.0
PYH2_k127_6956525_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 492.0
PYH2_k127_6956525_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 483.0
PYH2_k127_697825_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 404.0
PYH2_k127_697825_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 379.0
PYH2_k127_697825_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 295.0
PYH2_k127_697825_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000008983 128.0
PYH2_k127_697825_4 - - - - 0.000001995 50.0
PYH2_k127_6978294_0 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 295.0
PYH2_k127_6978294_1 ferredoxin-type protein K02574 - - 0.000000000000000000000000000000000000000000000000003771 183.0
PYH2_k127_6978294_2 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000009944 164.0
PYH2_k127_69838_0 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 535.0
PYH2_k127_69838_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 317.0
PYH2_k127_6986839_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1142.0
PYH2_k127_6986839_1 Acyl-CoA dehydrogenase N terminal - - - 8.144e-277 861.0
PYH2_k127_6986839_10 - - - - 0.0000000000000000000000000001236 123.0
PYH2_k127_6986839_11 Serine aminopeptidase, S33 - - - 0.0006215 44.0
PYH2_k127_6986839_12 Transposase (IS116 IS110 IS902 family) - - - 0.000945 43.0
PYH2_k127_6986839_2 Belongs to the thiolase family K00632 - 2.3.1.16 2.459e-204 641.0
PYH2_k127_6986839_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 494.0
PYH2_k127_6986839_4 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 398.0
PYH2_k127_6986839_5 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 323.0
PYH2_k127_6986839_6 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000003829 215.0
PYH2_k127_6986839_7 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000002553 198.0
PYH2_k127_6986839_8 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000001923 176.0
PYH2_k127_6986839_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000002756 164.0
PYH2_k127_7032465_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2365.0
PYH2_k127_7032465_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2304.0
PYH2_k127_7032465_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000033 189.0
PYH2_k127_7032465_11 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000005117 154.0
PYH2_k127_7032465_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000006926 77.0
PYH2_k127_7032465_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1234.0
PYH2_k127_7032465_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.004e-238 737.0
PYH2_k127_7032465_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 338.0
PYH2_k127_7032465_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 302.0
PYH2_k127_7032465_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001732 270.0
PYH2_k127_7032465_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001118 267.0
PYH2_k127_7032465_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 246.0
PYH2_k127_7032465_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000002575 227.0
PYH2_k127_7041131_0 e1 component (alpha subunit) K00166 - 1.2.4.4 1.17e-199 630.0
PYH2_k127_7041131_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 607.0
PYH2_k127_7041131_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 560.0
PYH2_k127_7041131_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 545.0
PYH2_k127_7041131_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.000000000000000000000000000000000000003381 150.0
PYH2_k127_7041131_5 SMART Cold shock protein K03704 - - 0.0000000000000000000000005965 104.0
PYH2_k127_7071452_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 407.0
PYH2_k127_7071452_1 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 334.0
PYH2_k127_7071452_10 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000003142 176.0
PYH2_k127_7071452_11 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.0001461 47.0
PYH2_k127_7071452_2 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 329.0
PYH2_k127_7071452_3 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 323.0
PYH2_k127_7071452_4 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
PYH2_k127_7071452_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007599 272.0
PYH2_k127_7071452_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005542 261.0
PYH2_k127_7071452_7 Domain of unknown function (DUF4384) - - - 0.000000000000000000000000000000000000000000000000000000000000000005757 246.0
PYH2_k127_7071452_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000001137 210.0
PYH2_k127_7071452_9 - - - - 0.000000000000000000000000000000000000000000000000000002 198.0
PYH2_k127_7101893_0 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000001415 168.0
PYH2_k127_7101893_1 PFAM Archaeal ATPase - - - 0.0000000327 66.0
PYH2_k127_7101893_2 - - - - 0.00004968 51.0
PYH2_k127_7102770_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1514.0
PYH2_k127_7102770_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.077e-216 682.0
PYH2_k127_7102770_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 289.0
PYH2_k127_7102770_11 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001143 273.0
PYH2_k127_7102770_12 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
PYH2_k127_7102770_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000005998 237.0
PYH2_k127_7102770_14 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000009982 217.0
PYH2_k127_7102770_15 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000001143 223.0
PYH2_k127_7102770_16 Peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000008272 149.0
PYH2_k127_7102770_17 - - - - 0.000000000000000002164 92.0
PYH2_k127_7102770_18 Protein of unknown function (DUF465) - - - 0.00000000000000002227 83.0
PYH2_k127_7102770_19 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000001973 80.0
PYH2_k127_7102770_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.995e-206 658.0
PYH2_k127_7102770_3 Belongs to the thiolase family K00626 - 2.3.1.9 1.714e-197 629.0
PYH2_k127_7102770_4 HELICc2 K03722 - 3.6.4.12 3.282e-196 636.0
PYH2_k127_7102770_5 Belongs to the thiolase family K00626 - 2.3.1.9 7.301e-195 613.0
PYH2_k127_7102770_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 445.0
PYH2_k127_7102770_7 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 404.0
PYH2_k127_7102770_8 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 396.0
PYH2_k127_7102770_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 318.0
PYH2_k127_7257959_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1087.0
PYH2_k127_7257959_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 542.0
PYH2_k127_7257959_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 453.0
PYH2_k127_7257959_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 421.0
PYH2_k127_7257959_4 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 418.0
PYH2_k127_7257959_5 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 345.0
PYH2_k127_7257959_6 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 333.0
PYH2_k127_7257959_7 PFAM thioesterase superfamily protein K01075 - 3.1.2.23 0.0000000000000000000000000001554 120.0
PYH2_k127_7257959_8 Cysteine rich repeat - - - 0.000001016 60.0
PYH2_k127_7268473_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.866e-253 797.0
PYH2_k127_7268473_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 7.605e-232 731.0
PYH2_k127_7268473_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000007313 128.0
PYH2_k127_7268473_11 Preprotein translocase K03210 - - 0.00000000000000000000000000000006275 128.0
PYH2_k127_7268473_12 PFAM cytochrome c - - - 0.0000000000000000634 82.0
PYH2_k127_7268473_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 582.0
PYH2_k127_7268473_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 452.0
PYH2_k127_7268473_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 425.0
PYH2_k127_7268473_5 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 426.0
PYH2_k127_7268473_6 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 444.0
PYH2_k127_7268473_7 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 356.0
PYH2_k127_7268473_8 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
PYH2_k127_7268473_9 Cytochrome B561 - - - 0.0000000000000000000000000000000000000000000000000000000000003585 218.0
PYH2_k127_7268492_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 328.0
PYH2_k127_7268492_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000001602 139.0
PYH2_k127_7268492_2 Cytochrome C' - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000006878 85.0
PYH2_k127_7271230_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 437.0
PYH2_k127_7271230_1 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
PYH2_k127_7271230_2 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002936 254.0
PYH2_k127_7271230_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000009372 198.0
PYH2_k127_7271230_4 lipase activity - - - 0.0000000000000000000000000000000000000000000000000001053 199.0
PYH2_k127_7271230_5 PQ loop repeat K15383 - - 0.000000000000000000000000005366 115.0
PYH2_k127_7286506_0 Receptor family ligand binding region K01999 - - 2.167e-200 630.0
PYH2_k127_7286506_1 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 526.0
PYH2_k127_7286506_10 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007013 258.0
PYH2_k127_7286506_11 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006042 263.0
PYH2_k127_7286506_12 Endoribonuclease L-PSP - - - 0.00000000000000000000000000008332 121.0
PYH2_k127_7286506_13 ATPases associated with a variety of cellular activities K01996 - - 0.0000001694 56.0
PYH2_k127_7286506_14 Nucleotidyltransferase domain K07075 - - 0.000001775 51.0
PYH2_k127_7286506_15 branched-chain amino acid K01996 - - 0.00009942 49.0
PYH2_k127_7286506_2 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 507.0
PYH2_k127_7286506_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 380.0
PYH2_k127_7286506_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 355.0
PYH2_k127_7286506_5 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 344.0
PYH2_k127_7286506_6 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 334.0
PYH2_k127_7286506_7 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
PYH2_k127_7286506_8 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
PYH2_k127_7286506_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002008 272.0
PYH2_k127_7313953_0 AMP-binding enzyme C-terminal domain - - - 1.243e-235 738.0
PYH2_k127_7313953_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 450.0
PYH2_k127_7313953_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000005251 100.0
PYH2_k127_7313953_3 Universal stress protein - - - 0.000000000001128 71.0
PYH2_k127_7326918_0 oxidoreductase K04090 - 1.2.7.8 0.0 1451.0
PYH2_k127_7326918_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.926e-253 801.0
PYH2_k127_7326918_2 FAD dependent oxidoreductase - - - 1.707e-204 646.0
PYH2_k127_7326918_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 389.0
PYH2_k127_7326918_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 356.0
PYH2_k127_7326918_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 292.0
PYH2_k127_7326918_6 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001734 274.0
PYH2_k127_7326918_7 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
PYH2_k127_7326918_8 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000002899 212.0
PYH2_k127_7326918_9 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000005297 158.0
PYH2_k127_7341178_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 559.0
PYH2_k127_7341178_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 574.0
PYH2_k127_7341178_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 295.0
PYH2_k127_7341178_3 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 298.0
PYH2_k127_7341178_4 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000000000000003737 194.0
PYH2_k127_7341178_5 PEP-CTERM motif - - - 0.0000000000000001292 88.0
PYH2_k127_7343950_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 586.0
PYH2_k127_7343950_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 514.0
PYH2_k127_7343950_2 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000000000000000000000000000002196 246.0
PYH2_k127_7343950_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003406 231.0
PYH2_k127_7343950_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000011 115.0
PYH2_k127_738740_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 329.0
PYH2_k127_738740_1 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 290.0
PYH2_k127_738740_2 electron transfer activity K02305,K08738 - - 0.0000000000000000000000000000000000000000001099 168.0
PYH2_k127_738740_3 Transcriptional - - - 0.0000000000000000000000000000000000000003537 159.0
PYH2_k127_738740_4 Putative modulator of DNA gyrase - - - 0.00000000000000000000001525 102.0
PYH2_k127_738740_5 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000001206 79.0
PYH2_k127_7407500_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1746.0
PYH2_k127_7407500_1 5-oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 536.0
PYH2_k127_7407500_2 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 308.0
PYH2_k127_7407500_3 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000365 237.0
PYH2_k127_7407500_4 CoA-transferase family III - - - 0.0008146 43.0
PYH2_k127_7407652_0 SNARE associated Golgi protein - - - 2.003e-316 985.0
PYH2_k127_7407652_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 451.0
PYH2_k127_7407652_2 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
PYH2_k127_7407652_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005501 261.0
PYH2_k127_7407652_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
PYH2_k127_7407652_5 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000003047 140.0
PYH2_k127_7407652_6 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000005508 89.0
PYH2_k127_7407652_7 Transmembrane anti-sigma factor - - - 0.00001003 51.0
PYH2_k127_7433536_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1547.0
PYH2_k127_7433536_1 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 1.965e-300 931.0
PYH2_k127_7433536_10 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002364 279.0
PYH2_k127_7433536_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000003047 227.0
PYH2_k127_7433536_12 Complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
PYH2_k127_7433536_13 LysM domain K08086 - - 0.00000000000000000000000000000000000000000000000000006588 206.0
PYH2_k127_7433536_14 Sporulation related domain K03749 - - 0.000000000000000000000000002492 120.0
PYH2_k127_7433536_15 Ion channel - - - 0.0000000000000000000000001319 109.0
PYH2_k127_7433536_16 Colicin V production protein K03558 - - 0.0000000000000000000000009873 109.0
PYH2_k127_7433536_17 Staphylococcal nuclease homologues - - - 0.000000000000000000142 96.0
PYH2_k127_7433536_18 helix_turn_helix, Lux Regulon - - - 0.0000000000000009663 79.0
PYH2_k127_7433536_19 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000005152 77.0
PYH2_k127_7433536_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.623e-250 781.0
PYH2_k127_7433536_20 Alpha/beta hydrolase family - - - 0.00000000001318 67.0
PYH2_k127_7433536_21 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000888 60.0
PYH2_k127_7433536_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 9.207e-226 704.0
PYH2_k127_7433536_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 541.0
PYH2_k127_7433536_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 510.0
PYH2_k127_7433536_6 Periplasmic binding protein-like domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 502.0
PYH2_k127_7433536_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 478.0
PYH2_k127_7433536_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 364.0
PYH2_k127_7433536_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
PYH2_k127_7447792_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1017.0
PYH2_k127_7447792_1 carboxylase K01969 - 6.4.1.4 3.462e-292 903.0
PYH2_k127_7447792_10 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 420.0
PYH2_k127_7447792_11 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 350.0
PYH2_k127_7447792_12 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 332.0
PYH2_k127_7447792_13 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 328.0
PYH2_k127_7447792_14 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 317.0
PYH2_k127_7447792_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
PYH2_k127_7447792_16 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000003142 270.0
PYH2_k127_7447792_17 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005283 257.0
PYH2_k127_7447792_18 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
PYH2_k127_7447792_19 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
PYH2_k127_7447792_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 1.872e-276 867.0
PYH2_k127_7447792_20 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000005813 199.0
PYH2_k127_7447792_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000003071 188.0
PYH2_k127_7447792_22 - - - - 0.00000000000000000000000000000000000004238 163.0
PYH2_k127_7447792_23 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000000000001499 144.0
PYH2_k127_7447792_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000521 145.0
PYH2_k127_7447792_25 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000001197 120.0
PYH2_k127_7447792_26 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000002342 107.0
PYH2_k127_7447792_27 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000007112 97.0
PYH2_k127_7447792_28 HEPN domain - - - 0.000000000000001575 83.0
PYH2_k127_7447792_29 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000001654 67.0
PYH2_k127_7447792_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 542.0
PYH2_k127_7447792_30 HNH nucleases - - - 0.00001142 51.0
PYH2_k127_7447792_31 LemA family - - - 0.00003383 49.0
PYH2_k127_7447792_4 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 518.0
PYH2_k127_7447792_5 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 486.0
PYH2_k127_7447792_6 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 479.0
PYH2_k127_7447792_7 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 456.0
PYH2_k127_7447792_8 Hydroxymethylglutaryl-CoA lyase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 443.0
PYH2_k127_7447792_9 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
PYH2_k127_7475264_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.912e-240 750.0
PYH2_k127_7475264_1 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 504.0
PYH2_k127_7475264_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 434.0
PYH2_k127_7506440_0 Type VI secretion protein K11896 - - 3.823e-255 802.0
PYH2_k127_7506440_1 TIGRFAM type VI secretion ATPase, ClpV1 family K11907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 533.0
PYH2_k127_7506440_2 type VI secretion protein K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 321.0
PYH2_k127_7506440_3 Virulence protein SciE type K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 315.0
PYH2_k127_7506440_4 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.00000000000000000000000000000000000000000000000001733 187.0
PYH2_k127_7506440_5 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000768 145.0
PYH2_k127_7506440_6 - - - - 0.000000000001102 80.0
PYH2_k127_7506440_7 Type VI secretion system effector, Hcp K11903 - - 0.000000003156 57.0
PYH2_k127_7511825_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1053.0
PYH2_k127_7511825_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.175e-212 667.0
PYH2_k127_7511825_2 Alpha beta hydrolase K03821 - - 5.604e-207 661.0
PYH2_k127_7511825_3 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 447.0
PYH2_k127_7511825_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000009025 155.0
PYH2_k127_7511825_5 Domain of unknown function (DUF4437) - - - 0.0000000000005931 76.0
PYH2_k127_7517040_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1170.0
PYH2_k127_7517040_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 492.0
PYH2_k127_7567700_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
PYH2_k127_7578457_0 Peptidase C39 family K13409 - - 5.43e-203 653.0
PYH2_k127_7578457_1 Lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 448.0
PYH2_k127_7578457_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 408.0
PYH2_k127_7578457_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 292.0
PYH2_k127_7578457_4 HlyD family secretion protein K13408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004388 265.0
PYH2_k127_7578457_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001325 226.0
PYH2_k127_7578457_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000007779 66.0
PYH2_k127_75808_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 604.0
PYH2_k127_75808_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 590.0
PYH2_k127_75808_10 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000006363 112.0
PYH2_k127_75808_11 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000001451 79.0
PYH2_k127_75808_12 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000005159 70.0
PYH2_k127_75808_13 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000002477 63.0
PYH2_k127_75808_14 Transcriptional regulator K01719 - 4.2.1.75 0.0000001443 64.0
PYH2_k127_75808_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 569.0
PYH2_k127_75808_3 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
PYH2_k127_75808_4 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000001012 239.0
PYH2_k127_75808_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000003058 222.0
PYH2_k127_75808_6 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000003658 187.0
PYH2_k127_75808_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000001329 162.0
PYH2_k127_75808_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000000000002158 159.0
PYH2_k127_75808_9 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000002749 143.0
PYH2_k127_7602441_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 458.0
PYH2_k127_7602441_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 443.0
PYH2_k127_7602441_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 403.0
PYH2_k127_7602441_3 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 295.0
PYH2_k127_7602441_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000008376 252.0
PYH2_k127_7602441_5 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000000000005096 159.0
PYH2_k127_7602441_6 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000002281 130.0
PYH2_k127_7602441_7 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000004574 61.0
PYH2_k127_7619507_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 5.186e-199 631.0
PYH2_k127_7619507_1 binding-protein-dependent transport systems inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 593.0
PYH2_k127_7619507_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 530.0
PYH2_k127_7619507_3 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000004278 206.0
PYH2_k127_7667554_0 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 5.151e-211 661.0
PYH2_k127_7667554_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 487.0
PYH2_k127_7667554_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 312.0
PYH2_k127_7667554_3 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000007126 210.0
PYH2_k127_7667554_4 COG1960 Acyl-CoA dehydrogenases - - - 0.0000007356 60.0
PYH2_k127_7669379_0 Dynamin family - - - 2.917e-195 630.0
PYH2_k127_7669379_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 577.0
PYH2_k127_7669379_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004618 273.0
PYH2_k127_7669379_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000001795 242.0
PYH2_k127_7669379_12 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
PYH2_k127_7669379_13 PFAM peptidase S16 lon domain protein K07157 - - 0.0000000000000000000000000000000000000000000000000000001406 203.0
PYH2_k127_7669379_14 Phosphate starvation-inducible protein, PSIF - - - 0.00000000000000000000000000000002304 131.0
PYH2_k127_7669379_15 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000002016 98.0
PYH2_k127_7669379_16 Acetyltransferase (GNAT) family - - - 0.00000000007725 64.0
PYH2_k127_7669379_17 - - - - 0.0009645 43.0
PYH2_k127_7669379_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 523.0
PYH2_k127_7669379_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 429.0
PYH2_k127_7669379_4 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 387.0
PYH2_k127_7669379_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 377.0
PYH2_k127_7669379_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 340.0
PYH2_k127_7669379_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 333.0
PYH2_k127_7669379_8 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 324.0
PYH2_k127_7669379_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
PYH2_k127_7679044_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 500.0
PYH2_k127_7679044_1 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 424.0
PYH2_k127_7679044_10 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000002981 92.0
PYH2_k127_7679044_11 competence protein COMEC - - - 0.000000000000000005853 94.0
PYH2_k127_7679044_12 competence protein COMEC - - - 0.000000001077 69.0
PYH2_k127_7679044_13 extracellular polysaccharide biosynthetic process K16554 - - 0.00000004705 55.0
PYH2_k127_7679044_14 Psort location Cytoplasmic, score - - - 0.0009344 46.0
PYH2_k127_7679044_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 428.0
PYH2_k127_7679044_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 341.0
PYH2_k127_7679044_4 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000253 274.0
PYH2_k127_7679044_5 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003347 246.0
PYH2_k127_7679044_6 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002854 251.0
PYH2_k127_7679044_7 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000001405 222.0
PYH2_k127_7679044_8 GDYXXLXY protein - - - 0.0000000000000000000000000000000000000000000000000000000001075 224.0
PYH2_k127_7679044_9 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000000001377 96.0
PYH2_k127_7688070_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 549.0
PYH2_k127_7688070_1 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 302.0
PYH2_k127_7688070_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000002393 64.0
PYH2_k127_7704742_0 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 427.0
PYH2_k127_7704742_1 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 386.0
PYH2_k127_7704742_10 PFAM Major facilitator superfamily K02575 - - 0.00000000000000001431 85.0
PYH2_k127_7704742_2 GAF domain K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 380.0
PYH2_k127_7704742_3 ABC-2 family transporter protein K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 300.0
PYH2_k127_7704742_4 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001832 284.0
PYH2_k127_7704742_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
PYH2_k127_7704742_6 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002293 244.0
PYH2_k127_7704742_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000001476 168.0
PYH2_k127_7704742_8 EamA-like transporter family - - - 0.000000000000000000000000000001627 124.0
PYH2_k127_7704742_9 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000007038 121.0
PYH2_k127_7705049_0 Elements of external origin K07494 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 355.0
PYH2_k127_7705049_1 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003377 278.0
PYH2_k127_7705049_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000001809 168.0
PYH2_k127_7708734_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.632e-280 867.0
PYH2_k127_7708734_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.263e-272 840.0
PYH2_k127_7708734_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000002341 143.0
PYH2_k127_7708734_11 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000001396 126.0
PYH2_k127_7708734_12 ATP synthase I chain K02116 - - 0.000000000000001856 82.0
PYH2_k127_7708734_13 Glucose / Sorbosone dehydrogenase - - - 0.0000000000005512 72.0
PYH2_k127_7708734_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 420.0
PYH2_k127_7708734_3 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 412.0
PYH2_k127_7708734_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 400.0
PYH2_k127_7708734_5 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 354.0
PYH2_k127_7708734_6 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
PYH2_k127_7708734_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000008249 183.0
PYH2_k127_7708734_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000002828 184.0
PYH2_k127_7708734_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000001298 164.0
PYH2_k127_7716701_0 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 1.345e-216 685.0
PYH2_k127_7716701_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 381.0
PYH2_k127_7716701_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001636 260.0
PYH2_k127_7716701_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007553 247.0
PYH2_k127_7721384_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1355.0
PYH2_k127_7721384_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 3.469e-288 893.0
PYH2_k127_7721384_10 - - - - 0.000000009913 61.0
PYH2_k127_7721384_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.047e-224 710.0
PYH2_k127_7721384_3 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 589.0
PYH2_k127_7721384_4 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 431.0
PYH2_k127_7721384_5 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 341.0
PYH2_k127_7721384_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005522 270.0
PYH2_k127_7721384_7 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000553 219.0
PYH2_k127_7721384_8 Tricorn protease C1 domain K03797 - 3.4.21.102 0.0000000000000004323 87.0
PYH2_k127_7721384_9 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000001384 62.0
PYH2_k127_7724619_0 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 312.0
PYH2_k127_7724619_1 Fumarate hydratase (Fumerase) K01677,K03779 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000984 225.0
PYH2_k127_7724619_2 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000002304 209.0
PYH2_k127_7731155_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
PYH2_k127_7731155_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000004465 97.0
PYH2_k127_7735383_0 Sodium calcium K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 480.0
PYH2_k127_7735383_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
PYH2_k127_7735383_2 Putative transposase - - - 0.00000000000009527 81.0
PYH2_k127_7735383_3 Putative transposase - - - 0.000000000001344 69.0
PYH2_k127_7735383_4 PFAM Methyltransferase type 11 - - - 0.000000001615 66.0
PYH2_k127_7735383_5 - - - - 0.00001912 52.0
PYH2_k127_7735383_6 ubiE/COQ5 methyltransferase family - - - 0.00004667 52.0
PYH2_k127_7778077_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.218e-301 947.0
PYH2_k127_7778077_1 Proton-conducting membrane transporter - - - 7.676e-201 632.0
PYH2_k127_7778077_2 glycosyl transferase K21011 - - 1.128e-197 630.0
PYH2_k127_7778077_3 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 567.0
PYH2_k127_7778077_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 552.0
PYH2_k127_7778077_5 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000177 288.0
PYH2_k127_7778077_6 copG family - - - 0.0000000000000000000005622 100.0
PYH2_k127_7778077_7 aspartyl asparaginyl K12979 - - 0.000000000533 64.0
PYH2_k127_7778077_8 KR domain K00019 - 1.1.1.30 0.0001444 49.0
PYH2_k127_7783215_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 461.0
PYH2_k127_7783215_1 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 391.0
PYH2_k127_7783215_2 Lysine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
PYH2_k127_7783215_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
PYH2_k127_7783215_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000009521 211.0
PYH2_k127_7783215_5 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000222 130.0
PYH2_k127_7783215_6 Phosphopantetheine attachment site - - - 0.00000000000000000009043 99.0
PYH2_k127_7783215_7 Transglutaminase-like superfamily - - - 0.00000000881 60.0
PYH2_k127_7803005_0 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 423.0
PYH2_k127_7803005_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000009795 188.0
PYH2_k127_7803005_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000003874 175.0
PYH2_k127_7803005_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000005498 130.0
PYH2_k127_7826992_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.305e-211 672.0
PYH2_k127_7826992_1 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 452.0
PYH2_k127_7826992_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000018 251.0
PYH2_k127_7834651_0 ankyrin repeats - - - 2.277e-250 792.0
PYH2_k127_7834651_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000008333 153.0
PYH2_k127_7834651_2 - - - - 0.0000000000000000000000000005645 118.0
PYH2_k127_7834651_3 Helix-turn-helix domain - - - 0.000000000000003747 77.0
PYH2_k127_7865513_0 AcrB/AcrD/AcrF family - - - 0.0 1620.0
PYH2_k127_7865513_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 3.067e-249 790.0
PYH2_k127_7865513_2 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 546.0
PYH2_k127_7865513_3 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 484.0
PYH2_k127_7865513_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 405.0
PYH2_k127_7865513_5 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.0000000000000000000000000000000000001684 151.0
PYH2_k127_7865513_6 ABC-type dipeptide transport system, periplasmic component K02035,K12368 - - 0.000000000000000000000133 98.0
PYH2_k127_7865896_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 434.0
PYH2_k127_7865896_1 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 341.0
PYH2_k127_7865896_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 326.0
PYH2_k127_7865896_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000003665 232.0
PYH2_k127_7865896_4 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000004101 234.0
PYH2_k127_7865896_5 - - - - 0.00000000000004108 79.0
PYH2_k127_7865896_6 Protein of unknown function (DUF2934) - - - 0.0000004409 57.0
PYH2_k127_7868452_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 536.0
PYH2_k127_7868452_1 - - - - 0.00000000000004102 76.0
PYH2_k127_7877145_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
PYH2_k127_7877145_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 509.0
PYH2_k127_7877145_2 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 495.0
PYH2_k127_7877145_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 427.0
PYH2_k127_7877145_4 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 372.0
PYH2_k127_7877145_5 - - - - 0.000000000000000000000000000000000000000001246 167.0
PYH2_k127_7877145_6 Protein of unknown function (DUF2846) - - - 0.000000000000000000001285 99.0
PYH2_k127_7877145_7 Putative zinc ribbon domain - - - 0.00000000000000000002015 94.0
PYH2_k127_7882085_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 583.0
PYH2_k127_7882085_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 492.0
PYH2_k127_7882085_10 Domain of unknown function (DUF4397) - - - 0.000004109 53.0
PYH2_k127_7882085_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000005323 51.0
PYH2_k127_7882085_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 463.0
PYH2_k127_7882085_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 351.0
PYH2_k127_7882085_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
PYH2_k127_7882085_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003268 277.0
PYH2_k127_7882085_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000004615 264.0
PYH2_k127_7882085_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
PYH2_k127_7882085_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004103 218.0
PYH2_k127_7882085_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000002722 104.0
PYH2_k127_7887266_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 2.579e-244 763.0
PYH2_k127_7887266_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 584.0
PYH2_k127_7887266_2 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000007131 211.0
PYH2_k127_7887266_3 - - - - 0.0000000001107 68.0
PYH2_k127_7887266_4 - - - - 0.00002354 48.0
PYH2_k127_7894373_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 584.0
PYH2_k127_7894373_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000001425 117.0
PYH2_k127_7894373_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000002953 96.0
PYH2_k127_7894373_3 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.00000000000000005817 81.0
PYH2_k127_7894373_4 -acetyltransferase - - - 0.000000000002196 67.0
PYH2_k127_7894373_5 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000009244 56.0
PYH2_k127_7897570_0 NADPH-dependent glutamate synthase beta - - - 6.94e-311 963.0
PYH2_k127_7897570_1 Fe-S oxidoreductase K21834 - - 7.313e-287 885.0
PYH2_k127_7897570_10 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 410.0
PYH2_k127_7897570_11 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 354.0
PYH2_k127_7897570_12 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 345.0
PYH2_k127_7897570_13 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 338.0
PYH2_k127_7897570_14 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 289.0
PYH2_k127_7897570_15 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003231 258.0
PYH2_k127_7897570_16 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000004392 249.0
PYH2_k127_7897570_17 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000262 198.0
PYH2_k127_7897570_18 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000165 197.0
PYH2_k127_7897570_19 Belongs to the DsrF TusC family K07236 - - 0.0000000000000000000000000000000000000000000000003879 177.0
PYH2_k127_7897570_2 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.763e-248 770.0
PYH2_k127_7897570_20 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000005283 162.0
PYH2_k127_7897570_21 Cas6 Crispr - - - 0.00000000000000000000000000000000000000005033 160.0
PYH2_k127_7897570_22 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000003132 156.0
PYH2_k127_7897570_23 - - - - 0.0000000000000000000000000000000000000006027 160.0
PYH2_k127_7897570_24 DsrC like protein K11179 - - 0.000000000000000000000000000000000000009714 153.0
PYH2_k127_7897570_25 DsrH like protein K07237 - - 0.0000000000000000000000000000000001294 134.0
PYH2_k127_7897570_26 - - - - 0.000000000000000000000001189 109.0
PYH2_k127_7897570_27 PFAM CBS domain containing protein - - - 0.00000000000000000000009755 104.0
PYH2_k127_7897570_28 - - - - 0.0000000000000000000005424 98.0
PYH2_k127_7897570_29 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000004604 91.0
PYH2_k127_7897570_3 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 1.264e-230 731.0
PYH2_k127_7897570_30 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000004665 79.0
PYH2_k127_7897570_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 4.9e-220 692.0
PYH2_k127_7897570_5 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 7.317e-213 664.0
PYH2_k127_7897570_6 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 588.0
PYH2_k127_7897570_7 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 480.0
PYH2_k127_7897570_8 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 478.0
PYH2_k127_7897570_9 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 448.0
PYH2_k127_7959588_0 peptidase M24 K01262 - 3.4.11.9 4.842e-255 799.0
PYH2_k127_7959588_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 5.847e-211 667.0
PYH2_k127_7959588_10 Beta-lactamase - - - 0.00000000000000000000000000000000000005493 148.0
PYH2_k127_7959588_11 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000001516 146.0
PYH2_k127_7959588_12 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000558 112.0
PYH2_k127_7959588_13 - - - - 0.000000000000000002803 91.0
PYH2_k127_7959588_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00001739 54.0
PYH2_k127_7959588_15 - - - - 0.0002626 45.0
PYH2_k127_7959588_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 393.0
PYH2_k127_7959588_3 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 385.0
PYH2_k127_7959588_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 360.0
PYH2_k127_7959588_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
PYH2_k127_7959588_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
PYH2_k127_7959588_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
PYH2_k127_7959588_8 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006857 244.0
PYH2_k127_7959588_9 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000001652 237.0
PYH2_k127_7999_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 411.0
PYH2_k127_7999_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 344.0
PYH2_k127_7999_2 Protein of unknown function (DUF3429) - - - 0.000000000000000007306 91.0
PYH2_k127_7999_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.00000000000002892 75.0
PYH2_k127_8015762_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 445.0
PYH2_k127_8015762_1 Type II secretory pathway, component ExeA K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 432.0
PYH2_k127_8015762_2 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002674 284.0
PYH2_k127_8015762_3 Ureidoglycolate lyase - - - 0.00002409 48.0
PYH2_k127_8055763_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 570.0
PYH2_k127_8055763_1 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 384.0
PYH2_k127_8055763_2 peptidyl-prolyl K03775 - 5.2.1.8 0.0000000000000000000000000000000104 134.0
PYH2_k127_8055763_3 - - - - 0.000000009025 66.0
PYH2_k127_8090205_0 Tetratricopeptide repeat - - - 2.141e-231 733.0
PYH2_k127_8090205_1 Tetratricopeptide repeat - - - 7.023e-220 698.0
PYH2_k127_8090205_2 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 498.0
PYH2_k127_8090205_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001068 279.0
PYH2_k127_8090205_4 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003033 259.0
PYH2_k127_8090205_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000189 126.0
PYH2_k127_8105461_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1151.0
PYH2_k127_8105461_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 450.0
PYH2_k127_8105461_2 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 435.0
PYH2_k127_8105461_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
PYH2_k127_8105461_4 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 389.0
PYH2_k127_8105461_5 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 373.0
PYH2_k127_8105461_6 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
PYH2_k127_8105461_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001334 136.0
PYH2_k127_8141973_0 ABC transporter transmembrane region K06148,K12536 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 508.0
PYH2_k127_8141973_1 Sulfotransferase domain - - - 0.000000000000000000000000000005737 121.0
PYH2_k127_8145677_0 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 452.0
PYH2_k127_8145677_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 381.0
PYH2_k127_8145677_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 299.0
PYH2_k127_8145677_3 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000001493 214.0
PYH2_k127_8145677_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000001309 120.0
PYH2_k127_8145677_5 Mechanosensitive ion channel - - - 0.000001625 53.0
PYH2_k127_8149029_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 606.0
PYH2_k127_8149029_1 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 385.0
PYH2_k127_8149029_2 ATPases associated with a variety of cellular activities K10025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 376.0
PYH2_k127_8149029_3 Ligated ion channel L-glutamate- and glycine-binding site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 329.0
PYH2_k127_8149029_4 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 300.0
PYH2_k127_8149029_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 289.0
PYH2_k127_8149029_6 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
PYH2_k127_8149029_7 Protein of unknown function (DUF1059) - - - 0.000000000000000000000000249 108.0
PYH2_k127_8149029_8 Glyoxalase bleomycin resistance - - - 0.000000000000162 71.0
PYH2_k127_8157975_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.4e-323 996.0
PYH2_k127_8157975_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.125e-239 750.0
PYH2_k127_8157975_10 Protein of unknown function (DUF1272) - - - 0.0000000000000000000000000000000000001706 142.0
PYH2_k127_8157975_11 Regulatory protein, FmdB family - - - 0.000000000000000000000000000002243 126.0
PYH2_k127_8157975_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000001115 112.0
PYH2_k127_8157975_2 ABC transporter transmembrane region K06147,K18893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 594.0
PYH2_k127_8157975_3 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 517.0
PYH2_k127_8157975_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 494.0
PYH2_k127_8157975_5 alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 453.0
PYH2_k127_8157975_6 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 302.0
PYH2_k127_8157975_7 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 308.0
PYH2_k127_8157975_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001747 245.0
PYH2_k127_8157975_9 Nudix hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000001143 192.0
PYH2_k127_8186739_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 551.0
PYH2_k127_8186739_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 394.0
PYH2_k127_8265116_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1508.0
PYH2_k127_8265116_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1298.0
PYH2_k127_8265116_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.403e-208 656.0
PYH2_k127_8265116_100 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000000001112 110.0
PYH2_k127_8265116_101 membrane K06077 - - 0.0000000000000000000000001844 111.0
PYH2_k127_8265116_102 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000001015 102.0
PYH2_k127_8265116_103 Histidine kinase-like ATPase domain - - - 0.0000000000000000000002882 101.0
PYH2_k127_8265116_104 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000008307 89.0
PYH2_k127_8265116_105 Flagellar protein FliT K02423 - - 0.00000000000000000106 92.0
PYH2_k127_8265116_106 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000002949 83.0
PYH2_k127_8265116_107 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000000000000009552 84.0
PYH2_k127_8265116_108 - - - - 0.0000000000000001054 90.0
PYH2_k127_8265116_109 Malic enzyme, NAD binding domain K00027,K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40 0.000000000000001636 79.0
PYH2_k127_8265116_11 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 6.44e-208 649.0
PYH2_k127_8265116_110 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000006975 78.0
PYH2_k127_8265116_111 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000005895 72.0
PYH2_k127_8265116_112 Flagellar hook-length control protein FliK - - - 0.0000000005745 71.0
PYH2_k127_8265116_113 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000007877 64.0
PYH2_k127_8265116_114 Belongs to the ParA family K04562 - - 0.000000008659 66.0
PYH2_k127_8265116_115 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000128 54.0
PYH2_k127_8265116_116 - K06950 - - 0.000002712 59.0
PYH2_k127_8265116_117 Patatin-like phospholipase K07001 - - 0.000009605 52.0
PYH2_k127_8265116_118 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000107 56.0
PYH2_k127_8265116_119 Malic enzyme K00029 - 1.1.1.40 0.00001774 47.0
PYH2_k127_8265116_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 7.317e-205 647.0
PYH2_k127_8265116_120 FlaG protein K06603 - - 0.00003329 51.0
PYH2_k127_8265116_121 malic enzyme K00029 - 1.1.1.40 0.00007774 45.0
PYH2_k127_8265116_122 Protein of unknown function (DUF721) - - - 0.0001857 51.0
PYH2_k127_8265116_123 - - - - 0.0002231 46.0
PYH2_k127_8265116_13 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.277e-203 655.0
PYH2_k127_8265116_14 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 607.0
PYH2_k127_8265116_15 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 610.0
PYH2_k127_8265116_16 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 579.0
PYH2_k127_8265116_17 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 555.0
PYH2_k127_8265116_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 591.0
PYH2_k127_8265116_19 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 556.0
PYH2_k127_8265116_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.158e-275 858.0
PYH2_k127_8265116_20 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 546.0
PYH2_k127_8265116_21 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 561.0
PYH2_k127_8265116_22 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 542.0
PYH2_k127_8265116_23 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 550.0
PYH2_k127_8265116_24 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 536.0
PYH2_k127_8265116_25 Sigma-54 interaction domain K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 542.0
PYH2_k127_8265116_26 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 538.0
PYH2_k127_8265116_27 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 497.0
PYH2_k127_8265116_28 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 497.0
PYH2_k127_8265116_29 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 502.0
PYH2_k127_8265116_3 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.339e-268 844.0
PYH2_k127_8265116_30 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 483.0
PYH2_k127_8265116_31 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 457.0
PYH2_k127_8265116_32 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 466.0
PYH2_k127_8265116_33 Flagellar basal body rod protein K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 445.0
PYH2_k127_8265116_34 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 441.0
PYH2_k127_8265116_35 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 421.0
PYH2_k127_8265116_36 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 407.0
PYH2_k127_8265116_37 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 410.0
PYH2_k127_8265116_38 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 395.0
PYH2_k127_8265116_39 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 388.0
PYH2_k127_8265116_4 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 9.263e-259 804.0
PYH2_k127_8265116_40 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 383.0
PYH2_k127_8265116_41 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 377.0
PYH2_k127_8265116_42 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 354.0
PYH2_k127_8265116_43 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
PYH2_k127_8265116_44 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 344.0
PYH2_k127_8265116_45 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 341.0
PYH2_k127_8265116_46 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH2_k127_8265116_47 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 317.0
PYH2_k127_8265116_48 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 329.0
PYH2_k127_8265116_49 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 317.0
PYH2_k127_8265116_5 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.636e-251 779.0
PYH2_k127_8265116_50 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
PYH2_k127_8265116_51 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 310.0
PYH2_k127_8265116_52 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 322.0
PYH2_k127_8265116_53 FHA Domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
PYH2_k127_8265116_54 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 289.0
PYH2_k127_8265116_55 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 294.0
PYH2_k127_8265116_56 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 291.0
PYH2_k127_8265116_57 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000612 313.0
PYH2_k127_8265116_58 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001216 281.0
PYH2_k127_8265116_59 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005057 291.0
PYH2_k127_8265116_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 4.861e-246 771.0
PYH2_k127_8265116_60 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
PYH2_k127_8265116_61 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 271.0
PYH2_k127_8265116_62 Rod binding protein K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003003 280.0
PYH2_k127_8265116_63 Flagellar basal-body rod protein FlgF K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
PYH2_k127_8265116_64 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003506 265.0
PYH2_k127_8265116_65 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008442 265.0
PYH2_k127_8265116_66 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 254.0
PYH2_k127_8265116_67 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
PYH2_k127_8265116_68 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000007578 249.0
PYH2_k127_8265116_69 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000001078 233.0
PYH2_k127_8265116_7 RNB K01147 - 3.1.13.1 5.269e-219 697.0
PYH2_k127_8265116_70 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005426 231.0
PYH2_k127_8265116_71 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000005152 222.0
PYH2_k127_8265116_72 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000000000000000000000000000000000003813 231.0
PYH2_k127_8265116_73 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000003563 214.0
PYH2_k127_8265116_74 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000005059 222.0
PYH2_k127_8265116_75 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000005757 195.0
PYH2_k127_8265116_76 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000003226 194.0
PYH2_k127_8265116_77 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000004366 197.0
PYH2_k127_8265116_78 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
PYH2_k127_8265116_79 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000001589 196.0
PYH2_k127_8265116_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.454e-213 677.0
PYH2_k127_8265116_80 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000004369 187.0
PYH2_k127_8265116_81 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000002467 185.0
PYH2_k127_8265116_82 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000002557 178.0
PYH2_k127_8265116_83 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000000000000000278 175.0
PYH2_k127_8265116_84 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000006331 171.0
PYH2_k127_8265116_85 YbaK prolyl-tRNA synthetase associated - - - 0.00000000000000000000000000000000000000000006364 170.0
PYH2_k127_8265116_86 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000002297 170.0
PYH2_k127_8265116_87 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000001819 159.0
PYH2_k127_8265116_88 YGGT family K02221 - - 0.00000000000000000000000000000000000000001019 160.0
PYH2_k127_8265116_89 mRNA catabolic process - - - 0.0000000000000000000000000000000000000002019 157.0
PYH2_k127_8265116_9 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 6.566e-213 677.0
PYH2_k127_8265116_90 Redoxin domain protein - - - 0.000000000000000000000000000000000000005058 152.0
PYH2_k127_8265116_91 LuxR family transcriptional regulator K13041 - - 0.00000000000000000000000000000000000002032 152.0
PYH2_k127_8265116_92 zinc-ribbon domain - - - 0.000000000000000000000000000000000003209 151.0
PYH2_k127_8265116_93 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000001785 137.0
PYH2_k127_8265116_94 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000001402 144.0
PYH2_k127_8265116_95 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000000000000000000004038 141.0
PYH2_k127_8265116_96 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000001002 127.0
PYH2_k127_8265116_97 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000001381 130.0
PYH2_k127_8265116_98 KTSC domain - - - 0.000000000000000000000000000007043 119.0
PYH2_k127_8265116_99 Flagellar protein FliS K02422 - - 0.0000000000000000000000000008467 118.0
PYH2_k127_8352456_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1163.0
PYH2_k127_8352456_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1016.0
PYH2_k127_8352456_2 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 387.0
PYH2_k127_8352456_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 325.0
PYH2_k127_8352456_4 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
PYH2_k127_8352456_5 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004414 248.0
PYH2_k127_8352456_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000006431 132.0
PYH2_k127_8390282_0 Phosphoglucomutase K01835 - 5.4.2.2 4.536e-252 786.0
PYH2_k127_8390282_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.109e-203 640.0
PYH2_k127_8390282_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 528.0
PYH2_k127_8390282_3 TOBE domain K10112 - - 0.00000000000000000000000007695 109.0
PYH2_k127_840352_0 GTP-binding protein K06207 - - 0.0 1006.0
PYH2_k127_840352_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.877e-301 932.0
PYH2_k127_840352_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
PYH2_k127_840352_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 289.0
PYH2_k127_840352_4 glutamate--cysteine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001416 274.0
PYH2_k127_840352_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000001279 164.0
PYH2_k127_840352_6 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000001889 92.0
PYH2_k127_8446040_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.972e-216 691.0
PYH2_k127_8446040_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 599.0
PYH2_k127_8446040_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 577.0
PYH2_k127_8446040_3 PFAM extracellular solute-binding protein family 1 K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 391.0
PYH2_k127_8446040_4 - - - - 0.000000000000000000000000000000000000000000005466 177.0
PYH2_k127_8450161_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.537e-240 745.0
PYH2_k127_8450161_1 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 501.0
PYH2_k127_8452324_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1148.0
PYH2_k127_8452324_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 624.0
PYH2_k127_8452324_10 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000000000000000005218 214.0
PYH2_k127_8452324_11 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000001501 203.0
PYH2_k127_8452324_12 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000003929 198.0
PYH2_k127_8452324_13 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000005542 158.0
PYH2_k127_8452324_14 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000003862 150.0
PYH2_k127_8452324_2 Heavy-metal-associated domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 526.0
PYH2_k127_8452324_3 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
PYH2_k127_8452324_4 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 374.0
PYH2_k127_8452324_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 365.0
PYH2_k127_8452324_6 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 364.0
PYH2_k127_8452324_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 335.0
PYH2_k127_8452324_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000002145 250.0
PYH2_k127_8452324_9 PFAM Fructosamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001058 253.0
PYH2_k127_8478386_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2219.0
PYH2_k127_8478386_1 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1367.0
PYH2_k127_8478386_2 FAD binding domain - - - 0.0 1135.0
PYH2_k127_8478386_3 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 1.091e-214 692.0
PYH2_k127_8478386_4 Magnesium transport protein CorA - - - 6.389e-213 674.0
PYH2_k127_8478386_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
PYH2_k127_8478386_6 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000003999 188.0
PYH2_k127_8478386_7 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000000000000002964 143.0
PYH2_k127_8478386_8 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000002681 88.0
PYH2_k127_8491914_0 - - - - 0.000000000000000000000000000000000000000000000002795 179.0
PYH2_k127_8491914_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000009344 186.0
PYH2_k127_8491914_2 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000001525 102.0
PYH2_k127_8504933_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 472.0
PYH2_k127_8504933_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 380.0
PYH2_k127_8504933_2 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 343.0
PYH2_k127_8504933_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000007836 68.0
PYH2_k127_8528839_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 582.0
PYH2_k127_8528839_1 UTRA domain K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 336.0
PYH2_k127_8528839_2 Psort location Cytoplasmic, score 8.96 K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000001242 196.0
PYH2_k127_8528839_3 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000000000000000000000000000000157 135.0
PYH2_k127_8533523_0 Dehydratase family K13875 - 4.2.1.25 5.784e-303 936.0
PYH2_k127_8533523_1 Bacterial extracellular solute-binding protein K02027 - - 3.108e-212 670.0
PYH2_k127_8533523_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 511.0
PYH2_k127_8533523_3 ABC-type sugar K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
PYH2_k127_8533523_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 441.0
PYH2_k127_8533523_5 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 440.0
PYH2_k127_8533523_6 PFAM NAD-dependent epimerase dehydratase K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
PYH2_k127_8533523_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000002369 74.0
PYH2_k127_8556039_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.042e-218 688.0
PYH2_k127_8556039_1 Cell shape determining protein, MreB Mrl family K03569 - - 1.292e-198 623.0
PYH2_k127_8556039_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
PYH2_k127_8556039_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
PYH2_k127_8556039_4 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000001468 234.0
PYH2_k127_8556039_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000006312 119.0
PYH2_k127_8573955_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.299e-264 825.0
PYH2_k127_8573955_1 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 7.728e-218 684.0
PYH2_k127_8573955_2 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
PYH2_k127_8573955_3 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 370.0
PYH2_k127_8573955_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000001322 184.0
PYH2_k127_8573955_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000001728 147.0
PYH2_k127_8584030_0 CoA binding domain K09181 - - 9.733e-262 835.0
PYH2_k127_8584030_1 cephalosporin hydroxylase K01190,K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 288.0
PYH2_k127_8584030_2 TraB family K09973 - - 0.0000000000000000000000000000000000000000000006281 177.0
PYH2_k127_8587334_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 574.0
PYH2_k127_8587334_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 327.0
PYH2_k127_8587334_2 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000009222 221.0
PYH2_k127_8587334_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000002145 218.0
PYH2_k127_8587334_4 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000002487 207.0
PYH2_k127_8587334_5 - - - - 0.00000000000000000000000000000006622 128.0
PYH2_k127_8587334_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00003242 49.0
PYH2_k127_8591054_0 membrane-associated Zn-dependent proteases 1 - - - 8.293e-227 723.0
PYH2_k127_8591054_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 592.0
PYH2_k127_8591054_10 Belongs to the ParB family K03497 - - 0.0000000000003896 73.0
PYH2_k127_8591054_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000804 61.0
PYH2_k127_8591054_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 565.0
PYH2_k127_8591054_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
PYH2_k127_8591054_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 374.0
PYH2_k127_8591054_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 342.0
PYH2_k127_8591054_6 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001165 276.0
PYH2_k127_8591054_7 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000002251 168.0
PYH2_k127_8591054_8 - - - - 0.000000000000000000002403 96.0
PYH2_k127_8591054_9 CoA-substrate-specific enzyme activase - - - 0.00000000000000000007125 91.0
PYH2_k127_8608840_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.751e-247 777.0
PYH2_k127_8608840_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.322e-220 698.0
PYH2_k127_8608840_2 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 4.516e-220 708.0
PYH2_k127_8608840_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 495.0
PYH2_k127_8608840_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 486.0
PYH2_k127_8608840_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000002609 161.0
PYH2_k127_8614026_0 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 444.0
PYH2_k127_8614026_1 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.00000000000000000000000000000000836 130.0
PYH2_k127_8614026_2 transport system fused permease components - - - 0.000000000000000000001064 96.0
PYH2_k127_8614026_3 Domain of unknown function (DUF1850) - - - 0.0000000000000005878 83.0
PYH2_k127_8614852_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1275.0
PYH2_k127_8614852_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 571.0
PYH2_k127_8614852_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 358.0
PYH2_k127_8620497_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 457.0
PYH2_k127_8620497_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000001374 148.0
PYH2_k127_8620497_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000004975 106.0
PYH2_k127_8628510_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 479.0
PYH2_k127_8628510_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000009749 209.0
PYH2_k127_8628510_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000001599 170.0
PYH2_k127_8628510_3 diguanylate cyclase - - - 0.000000000000000000000004332 118.0
PYH2_k127_8631549_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.386e-231 719.0
PYH2_k127_8631549_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.639e-211 667.0
PYH2_k127_8631549_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
PYH2_k127_8631549_11 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 310.0
PYH2_k127_8631549_12 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001904 264.0
PYH2_k127_8631549_13 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002568 252.0
PYH2_k127_8631549_14 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
PYH2_k127_8631549_15 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
PYH2_k127_8631549_16 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000224 227.0
PYH2_k127_8631549_17 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000008295 232.0
PYH2_k127_8631549_18 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000001274 216.0
PYH2_k127_8631549_19 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000005536 179.0
PYH2_k127_8631549_2 Peptidase family S49 K04773 - - 7.825e-211 672.0
PYH2_k127_8631549_20 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000004351 149.0
PYH2_k127_8631549_21 Protein of unknown function (DUF3299) K09950 - - 0.00000000000000000000000000000000003418 144.0
PYH2_k127_8631549_22 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000006446 95.0
PYH2_k127_8631549_23 - - - - 0.00000000000001832 76.0
PYH2_k127_8631549_24 Heavy-metal-associated domain - - - 0.0000000000002072 74.0
PYH2_k127_8631549_25 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000007923 49.0
PYH2_k127_8631549_3 Cobalamin biosynthesis protein CobW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 499.0
PYH2_k127_8631549_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 507.0
PYH2_k127_8631549_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 481.0
PYH2_k127_8631549_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 402.0
PYH2_k127_8631549_7 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 349.0
PYH2_k127_8631549_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 353.0
PYH2_k127_8631549_9 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 327.0
PYH2_k127_8633067_0 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 9.53e-246 774.0
PYH2_k127_8633067_1 Predicted membrane protein (DUF2339) - - - 1.299e-208 689.0
PYH2_k127_8633067_10 Domain of unknown function (DUF3597) - - - 0.00001663 51.0
PYH2_k127_8633067_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 453.0
PYH2_k127_8633067_3 hydrolase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 336.0
PYH2_k127_8633067_4 FAD dependent oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000002021 247.0
PYH2_k127_8633067_5 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005739 227.0
PYH2_k127_8633067_6 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000000003817 218.0
PYH2_k127_8633067_7 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000008763 198.0
PYH2_k127_8633067_8 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000006265 108.0
PYH2_k127_8633067_9 Pilin (bacterial filament) K02650 - - 0.000006541 53.0
PYH2_k127_8689807_0 type III restriction protein res subunit K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 487.0
PYH2_k127_8689807_1 regulation of methylation-dependent chromatin silencing K07454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 350.0
PYH2_k127_8689807_2 Domain of unknown function (DUF3883) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
PYH2_k127_8689807_3 PFAM plasmid K06218 - - 0.0000000000000000000000000004696 117.0
PYH2_k127_8689807_4 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.000000000000000000000000001058 119.0
PYH2_k127_8689807_5 - - - - 0.000000000000003859 80.0
PYH2_k127_8689807_6 transcription regulator containing HTH domain K18831 - - 0.000000002081 59.0
PYH2_k127_8690435_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1762.0
PYH2_k127_8690435_1 efflux pump K18138,K18146 - - 0.0 1454.0
PYH2_k127_8690435_10 repressor for the acrAB genes K03577 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000003385 172.0
PYH2_k127_8690435_11 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000000001128 162.0
PYH2_k127_8690435_12 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000007592 125.0
PYH2_k127_8690435_13 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000001321 125.0
PYH2_k127_8690435_14 - - - - 0.0000000000000000000000000004871 116.0
PYH2_k127_8690435_15 SMART Cold shock protein K03704 - - 0.000000000000000000002195 93.0
PYH2_k127_8690435_2 Fic/DOC family N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 486.0
PYH2_k127_8690435_3 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 400.0
PYH2_k127_8690435_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 395.0
PYH2_k127_8690435_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 377.0
PYH2_k127_8690435_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 320.0
PYH2_k127_8690435_7 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001341 244.0
PYH2_k127_8690435_8 Thioesterase K07107,K12500 - - 0.000000000000000000000000000000000000000000000000000001314 195.0
PYH2_k127_8690435_9 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000009272 183.0
PYH2_k127_8694648_0 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 609.0
PYH2_k127_8694648_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007847 243.0
PYH2_k127_8694648_10 - - - - 0.000000000000000726 78.0
PYH2_k127_8694648_11 Domain of unknown function (DUF1845) - - - 0.0000006545 55.0
PYH2_k127_8694648_12 - - - - 0.000006086 52.0
PYH2_k127_8694648_13 NnrU protein - - - 0.00001102 49.0
PYH2_k127_8694648_14 Putative ParB-like nuclease - - - 0.0004308 46.0
PYH2_k127_8694648_2 PIN domain - - - 0.0000000000000000000000000000000000000000001415 164.0
PYH2_k127_8694648_3 RES - - - 0.000000000000000000000000000000000000000001803 160.0
PYH2_k127_8694648_4 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000000000000000000006092 152.0
PYH2_k127_8694648_5 Domain of unknown function (DUF1845) - - - 0.000000000000000000000000000000000002508 144.0
PYH2_k127_8694648_6 Histidine kinase K20973 - 2.7.13.3 0.000000000000000000000000000008974 125.0
PYH2_k127_8694648_7 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000007768 112.0
PYH2_k127_8694648_8 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000197 106.0
PYH2_k127_8694648_9 Putative ParB-like nuclease - - - 0.00000000000000000000271 98.0
PYH2_k127_8698368_0 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 361.0
PYH2_k127_8698368_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 289.0
PYH2_k127_8698368_2 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
PYH2_k127_8698368_3 PFAM Cytochrome c, class I K08738 - - 0.000000000000000000000000000000000000000000000000001241 186.0
PYH2_k127_8698368_4 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000005375 188.0
PYH2_k127_8698368_5 amine dehydrogenase activity K13730 - - 0.00000003448 65.0
PYH2_k127_8730967_0 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 359.0
PYH2_k127_8730967_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000004846 235.0
PYH2_k127_8730967_2 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000000000001914 209.0
PYH2_k127_8730967_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000004901 114.0
PYH2_k127_8730967_4 LTXXQ motif family protein - - - 0.0002695 50.0
PYH2_k127_8733385_0 Ammonium transporter K03320 - - 5.473e-229 723.0
PYH2_k127_8733385_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 3.351e-226 710.0
PYH2_k127_8733385_10 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 363.0
PYH2_k127_8733385_11 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 372.0
PYH2_k127_8733385_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH2_k127_8733385_13 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009521 263.0
PYH2_k127_8733385_14 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
PYH2_k127_8733385_15 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
PYH2_k127_8733385_16 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001587 236.0
PYH2_k127_8733385_17 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000844 233.0
PYH2_k127_8733385_18 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
PYH2_k127_8733385_19 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000002791 230.0
PYH2_k127_8733385_2 Glutamate-cysteine ligase K01919 - 6.3.2.2 4.679e-198 629.0
PYH2_k127_8733385_20 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000000006701 214.0
PYH2_k127_8733385_21 Auxin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000002269 201.0
PYH2_k127_8733385_22 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000006841 195.0
PYH2_k127_8733385_23 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000002034 155.0
PYH2_k127_8733385_24 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000002833 116.0
PYH2_k127_8733385_25 Membrane fusogenic activity K09806 - - 0.000000000000000002329 89.0
PYH2_k127_8733385_26 Domain of unknown function (DUF4124) - - - 0.0000000000002254 79.0
PYH2_k127_8733385_27 Glycosyl transferases group 1 - - - 0.000000101 61.0
PYH2_k127_8733385_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 602.0
PYH2_k127_8733385_4 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 587.0
PYH2_k127_8733385_5 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 574.0
PYH2_k127_8733385_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 551.0
PYH2_k127_8733385_7 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 487.0
PYH2_k127_8733385_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 406.0
PYH2_k127_8733385_9 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 361.0
PYH2_k127_8735525_0 synthetase K01907 - 6.2.1.16 1.277e-284 893.0
PYH2_k127_8735525_1 abc transporter K15738 - - 1.701e-208 670.0
PYH2_k127_8735525_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 436.0
PYH2_k127_8735525_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 430.0
PYH2_k127_8735525_4 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 381.0
PYH2_k127_8735525_5 Glycine-zipper domain - - - 0.00000000000000000000000000000000000001926 150.0
PYH2_k127_8735525_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000003952 122.0
PYH2_k127_8735525_7 - - - - 0.0000000000000000000003117 101.0
PYH2_k127_8735525_8 PFAM MmgE PrpD family protein - - - 0.0000000000000000009461 89.0
PYH2_k127_8744409_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 5.46e-307 977.0
PYH2_k127_8744409_1 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 469.0
PYH2_k127_8744409_2 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 404.0
PYH2_k127_8744409_3 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 346.0
PYH2_k127_8744409_4 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 285.0
PYH2_k127_8744409_5 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000000000004826 213.0
PYH2_k127_8744409_6 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000000007671 154.0
PYH2_k127_8744409_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.0000000000000000000000000000000173 143.0
PYH2_k127_8744409_8 Na+/H+ antiporter subunit K05564,K05571 - - 0.00000000000000000000000000002089 124.0
PYH2_k127_8744409_9 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.000000000000000000000003131 105.0
PYH2_k127_8745939_0 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 416.0
PYH2_k127_8745939_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH2_k127_8745939_2 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000006476 179.0
PYH2_k127_8766824_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1247.0
PYH2_k127_8766824_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 8.944e-232 722.0
PYH2_k127_8766824_2 Male sterility protein K02473 - 5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 489.0
PYH2_k127_8766824_3 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 437.0
PYH2_k127_8766824_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 304.0
PYH2_k127_8766824_5 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003071 248.0
PYH2_k127_8766824_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000001669 122.0
PYH2_k127_8766824_7 PEP-CTERM motif - - - 0.0002024 51.0
PYH2_k127_8779199_0 protein containing a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 607.0
PYH2_k127_8779199_1 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 565.0
PYH2_k127_8779199_2 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
PYH2_k127_8779199_3 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000002783 151.0
PYH2_k127_8779199_4 YHS domain protein - - - 0.000000000000000000000000000000008364 140.0
PYH2_k127_8779199_5 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0000000000000000000000000008767 115.0
PYH2_k127_8779199_6 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000005145 88.0
PYH2_k127_8779199_7 positive regulation of growth - - - 0.00000008049 58.0
PYH2_k127_8779199_8 PIN domain - - - 0.000001032 53.0
PYH2_k127_8806022_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1485.0
PYH2_k127_8806022_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 9.193e-318 980.0
PYH2_k127_8806022_10 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
PYH2_k127_8806022_11 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 279.0
PYH2_k127_8806022_12 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000295 224.0
PYH2_k127_8806022_13 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000000001206 198.0
PYH2_k127_8806022_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000000000000000000001895 177.0
PYH2_k127_8806022_15 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000000001203 163.0
PYH2_k127_8806022_16 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000004045 106.0
PYH2_k127_8806022_17 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000008757 104.0
PYH2_k127_8806022_18 PIN domain - - - 0.000000000000000000105 102.0
PYH2_k127_8806022_19 3' exoribonuclease, RNase T-like - - - 0.00000001602 67.0
PYH2_k127_8806022_2 MmgE/PrpD family K01720 - 4.2.1.79 4.68e-249 776.0
PYH2_k127_8806022_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.679e-221 689.0
PYH2_k127_8806022_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 557.0
PYH2_k127_8806022_5 Aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009279 492.0
PYH2_k127_8806022_6 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 458.0
PYH2_k127_8806022_7 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 451.0
PYH2_k127_8806022_8 DNA recombination protein, rmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 464.0
PYH2_k127_8806022_9 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 352.0
PYH2_k127_8816790_0 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000000004085 235.0
PYH2_k127_8816790_1 Hydrogenase expression formation protein K03605 - - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
PYH2_k127_8816790_2 Prokaryotic cytochrome b561 K03620 - - 0.00000000000000000000000000000000000000000000005289 171.0
PYH2_k127_8816790_3 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.0000000000000000000000000000000003 138.0
PYH2_k127_8816790_4 Rubredoxin - - - 0.0000000000000000000000000000004779 124.0
PYH2_k127_8816790_5 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000000000000000000008978 119.0
PYH2_k127_8816790_6 Hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000009205 111.0
PYH2_k127_8816790_7 Helix-turn-helix K21498 - - 0.000000000000000000000008547 110.0
PYH2_k127_8816790_8 Nickel-dependent hydrogenase - - - 0.00000000000000002143 90.0
PYH2_k127_8836736_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.568e-276 860.0
PYH2_k127_8836736_1 PFAM Peptidase family M20 M25 M40, Peptidase dimerization domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 550.0
PYH2_k127_8836736_2 FMN binding - - - 0.0000000000000000000000000001441 124.0
PYH2_k127_8841211_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 3.323e-243 760.0
PYH2_k127_8841211_1 COG0457 FOG TPR repeat - - - 3.422e-215 681.0
PYH2_k127_8841211_10 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 308.0
PYH2_k127_8841211_11 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
PYH2_k127_8841211_12 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 291.0
PYH2_k127_8841211_13 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
PYH2_k127_8841211_14 Cupin domain - - - 0.00000000000000000000000000000000000000000000001868 178.0
PYH2_k127_8841211_15 TIGRFAM DnaA regulatory inactivator Hda K10763 - - 0.000000000000000000000000000000000000000000000401 184.0
PYH2_k127_8841211_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000005194 166.0
PYH2_k127_8841211_17 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000613 166.0
PYH2_k127_8841211_18 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000005089 154.0
PYH2_k127_8841211_19 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000003765 116.0
PYH2_k127_8841211_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 558.0
PYH2_k127_8841211_20 DsrE/DsrF-like family K09004 - - 0.0000000000000000000001146 104.0
PYH2_k127_8841211_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 535.0
PYH2_k127_8841211_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 493.0
PYH2_k127_8841211_5 Patatin phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 466.0
PYH2_k127_8841211_6 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 463.0
PYH2_k127_8841211_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 376.0
PYH2_k127_8841211_8 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 347.0
PYH2_k127_8841211_9 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 332.0
PYH2_k127_8842790_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 321.0
PYH2_k127_8857240_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1049.0
PYH2_k127_8857240_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 7.907e-282 878.0
PYH2_k127_8857240_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001507 270.0
PYH2_k127_8857240_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001371 261.0
PYH2_k127_8857240_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006132 239.0
PYH2_k127_8857240_13 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
PYH2_k127_8857240_14 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000003484 194.0
PYH2_k127_8857240_15 2 iron, 2 sulfur cluster binding K22070,K22071 - - 0.00000000000000000000000000000000000000000000000001427 181.0
PYH2_k127_8857240_16 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000002287 181.0
PYH2_k127_8857240_17 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000001301 166.0
PYH2_k127_8857240_18 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000001082 132.0
PYH2_k127_8857240_19 nitrogen regulatory protein P-II - - - 0.000000000000000000000000003695 125.0
PYH2_k127_8857240_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.228e-239 747.0
PYH2_k127_8857240_20 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000002872 109.0
PYH2_k127_8857240_21 - - - - 0.00000000003726 68.0
PYH2_k127_8857240_22 - - - - 0.0000004473 61.0
PYH2_k127_8857240_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.033e-228 711.0
PYH2_k127_8857240_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.898e-212 674.0
PYH2_k127_8857240_5 His Kinase A (phosphoacceptor) domain - - - 2.643e-194 645.0
PYH2_k127_8857240_6 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 586.0
PYH2_k127_8857240_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 536.0
PYH2_k127_8857240_8 permease K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
PYH2_k127_8857240_9 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 370.0
PYH2_k127_8882899_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 420.0
PYH2_k127_8882899_1 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 360.0
PYH2_k127_8917620_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 4.866e-235 746.0
PYH2_k127_8917620_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 613.0
PYH2_k127_8917620_2 Multidrug ABC transporter permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 477.0
PYH2_k127_8917620_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 429.0
PYH2_k127_8917620_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 399.0
PYH2_k127_8917620_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 371.0
PYH2_k127_8917620_6 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 344.0
PYH2_k127_8917620_7 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 324.0
PYH2_k127_8917620_8 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000003951 105.0
PYH2_k127_8917620_9 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000002006 87.0
PYH2_k127_8933950_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.628e-299 939.0
PYH2_k127_8933950_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.428e-255 798.0
PYH2_k127_8933950_2 Belongs to the ABC transporter superfamily K10111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002687 272.0
PYH2_k127_8937326_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 464.0
PYH2_k127_8937326_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 317.0
PYH2_k127_8937326_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 290.0
PYH2_k127_8937326_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004386 255.0
PYH2_k127_8937326_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000004088 177.0
PYH2_k127_8937326_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000003636 167.0
PYH2_k127_8937326_6 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000114 126.0
PYH2_k127_8937326_7 protein conserved in bacteria - - - 0.00000000000000000000000145 115.0
PYH2_k127_8939444_0 transporter K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 518.0
PYH2_k127_8939444_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 481.0
PYH2_k127_8939444_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 475.0
PYH2_k127_8939444_3 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 352.0
PYH2_k127_8939444_4 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.0000000000000000000000000000000000000000000000000000000000001931 214.0
PYH2_k127_8939444_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000001222 157.0
PYH2_k127_8949738_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.461e-313 969.0
PYH2_k127_8949738_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 560.0
PYH2_k127_8949738_10 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 289.0
PYH2_k127_8949738_11 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000008538 240.0
PYH2_k127_8949738_12 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000000004113 206.0
PYH2_k127_8949738_13 Thiopurine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000003374 191.0
PYH2_k127_8949738_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000001224 153.0
PYH2_k127_8949738_15 - - - - 0.00000000000000000000000000000000000000357 160.0
PYH2_k127_8949738_16 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00001578 53.0
PYH2_k127_8949738_17 - - - - 0.0005497 51.0
PYH2_k127_8949738_2 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 525.0
PYH2_k127_8949738_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 508.0
PYH2_k127_8949738_4 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 396.0
PYH2_k127_8949738_5 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 393.0
PYH2_k127_8949738_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 418.0
PYH2_k127_8949738_7 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
PYH2_k127_8949738_8 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 404.0
PYH2_k127_8949738_9 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 365.0
PYH2_k127_8952086_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 409.0
PYH2_k127_8952086_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000001993 195.0
PYH2_k127_8952086_2 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000000009893 159.0
PYH2_k127_8952086_4 - - - - 0.0000000000000000000000000000461 117.0
PYH2_k127_8953489_0 Transposase DDE domain - - - 8.258e-257 799.0
PYH2_k127_8963651_0 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000000000007471 228.0
PYH2_k127_8963651_1 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000003099 147.0
PYH2_k127_8963651_2 Protein of unknown function (DUF2788) - - - 0.000000000000000000000002182 105.0
PYH2_k127_8963651_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000271 53.0
PYH2_k127_8986470_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.452e-205 654.0
PYH2_k127_8986470_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001056 119.0
PYH2_k127_8986470_2 - - - - 0.00000000000005382 78.0
PYH2_k127_8986470_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000294 56.0
PYH2_k127_8986470_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000001302 55.0
PYH2_k127_9003370_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 8.512e-302 930.0
PYH2_k127_9003370_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 326.0
PYH2_k127_901342_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 5e-323 994.0
PYH2_k127_901342_1 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 1.435e-204 642.0
PYH2_k127_901342_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 454.0
PYH2_k127_901342_3 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001512 279.0
PYH2_k127_901342_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000112 177.0
PYH2_k127_901342_5 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000006001 75.0
PYH2_k127_901342_6 Succinylglutamate desuccinylase - - - 0.000000000008379 72.0
PYH2_k127_901342_7 - - - - 0.0000002817 62.0
PYH2_k127_9014680_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 511.0
PYH2_k127_9014680_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 487.0
PYH2_k127_9014680_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 376.0
PYH2_k127_9014680_3 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 346.0
PYH2_k127_9014680_4 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 312.0
PYH2_k127_9014680_5 PFAM Negative transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000006672 179.0
PYH2_k127_9014680_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001255 166.0
PYH2_k127_9014680_7 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000006243 156.0
PYH2_k127_9032962_0 ABC transporter transmembrane region K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 600.0
PYH2_k127_9032962_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
PYH2_k127_9032962_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
PYH2_k127_9032962_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000001093 130.0
PYH2_k127_9032962_4 COG1132 ABC-type multidrug transport system, ATPase and permease components K18893 - - 0.0000000000001562 77.0
PYH2_k127_9060153_0 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 535.0
PYH2_k127_9060153_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 466.0
PYH2_k127_9060153_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 447.0
PYH2_k127_9111641_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005018 244.0
PYH2_k127_9111641_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000005267 229.0
PYH2_k127_9194934_0 Malic enzyme K00029 - 1.1.1.40 0.0 1082.0
PYH2_k127_9194934_1 Phosphoesterase family - - - 1.204e-198 631.0
PYH2_k127_9194934_2 aldo keto reductase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
PYH2_k127_9194934_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 363.0
PYH2_k127_9194934_4 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21607 - 1.1.1.404 0.00000000000000000000000000000000000000000000000000000000000000000001118 245.0
PYH2_k127_9194934_5 Related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001392 243.0
PYH2_k127_9194934_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008029 224.0
PYH2_k127_9194934_7 Acyl dehydratase - - - 0.00000000000000000000000000000000000000003174 158.0
PYH2_k127_9194934_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001876 146.0
PYH2_k127_9194934_9 signal peptide protein - - - 0.000007835 51.0
PYH2_k127_9222411_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1277.0
PYH2_k127_9222411_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 8.106e-270 834.0
PYH2_k127_9222411_10 cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000004449 205.0
PYH2_k127_9222411_11 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000004889 187.0
PYH2_k127_9222411_12 - - - - 0.0000000000000000000000000000000000000000000004654 171.0
PYH2_k127_9222411_13 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000000209 170.0
PYH2_k127_9222411_14 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000002413 171.0
PYH2_k127_9222411_15 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000003839 126.0
PYH2_k127_9222411_16 FixH family K09926 - - 0.000000000000000000000000000000607 128.0
PYH2_k127_9222411_17 - - - - 0.000000000000000000000000003104 114.0
PYH2_k127_9222411_18 - - - - 0.00000000000000002124 83.0
PYH2_k127_9222411_19 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000000005283 78.0
PYH2_k127_9222411_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 585.0
PYH2_k127_9222411_20 cytochrome oxidase maturation protein cbb3-type - - - 0.00000002709 57.0
PYH2_k127_9222411_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 587.0
PYH2_k127_9222411_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 383.0
PYH2_k127_9222411_5 Bacterial regulatory proteins, crp family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 353.0
PYH2_k127_9222411_6 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 331.0
PYH2_k127_9222411_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
PYH2_k127_9222411_8 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
PYH2_k127_9222411_9 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
PYH2_k127_9229995_0 C-methyltransferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 588.0
PYH2_k127_9229995_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 559.0
PYH2_k127_9229995_2 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 436.0
PYH2_k127_9229995_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 421.0
PYH2_k127_9229995_4 Cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 351.0
PYH2_k127_9229995_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000006164 244.0
PYH2_k127_9229995_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000007857 224.0
PYH2_k127_9229995_7 Bacterial transferase hexapeptide (six repeats) K13006 - - 0.00000000000000000000000000000000000000000000000000001265 196.0
PYH2_k127_9240767_0 - - - - 0.0 1733.0
PYH2_k127_9240767_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 606.0
PYH2_k127_9247264_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.885e-253 786.0
PYH2_k127_9247264_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 587.0
PYH2_k127_9247264_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 568.0
PYH2_k127_9247264_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
PYH2_k127_9247264_4 LysM domain K08086 - - 0.000000000000000000000000000000000000154 145.0
PYH2_k127_9247264_5 Entericidin EcnA/B family - - - 0.00000005334 55.0
PYH2_k127_9254176_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.043e-218 692.0
PYH2_k127_9254176_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 531.0
PYH2_k127_9254176_10 PFAM beta-lactamase domain protein - - - 0.0004509 46.0
PYH2_k127_9254176_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 520.0
PYH2_k127_9254176_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 448.0
PYH2_k127_9254176_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 276.0
PYH2_k127_9254176_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000003484 256.0
PYH2_k127_9254176_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
PYH2_k127_9254176_7 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000003838 174.0
PYH2_k127_9254176_8 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000000000000000001049 141.0
PYH2_k127_9254176_9 protein domain associated with - - - 0.0000000000000000000000000000000000397 146.0
PYH2_k127_9279315_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 459.0
PYH2_k127_9279315_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 381.0
PYH2_k127_9279315_2 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 K11906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000193 258.0
PYH2_k127_9279315_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000002171 196.0
PYH2_k127_9279315_4 CcdB protein K19163 - - 0.00004166 50.0
PYH2_k127_9304889_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
PYH2_k127_9304889_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 489.0
PYH2_k127_9304889_10 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000007938 150.0
PYH2_k127_9304889_11 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000001126 117.0
PYH2_k127_9304889_12 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000001331 121.0
PYH2_k127_9304889_13 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000008289 111.0
PYH2_k127_9304889_14 Protein of unknown function (DUF1289) K06938 - - 0.000000000000001108 79.0
PYH2_k127_9304889_15 - - - - 0.00000000003698 74.0
PYH2_k127_9304889_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 308.0
PYH2_k127_9304889_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
PYH2_k127_9304889_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000005249 224.0
PYH2_k127_9304889_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
PYH2_k127_9304889_7 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000008823 190.0
PYH2_k127_9304889_8 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000002303 180.0
PYH2_k127_9304889_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000004257 174.0
PYH2_k127_941886_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.906e-212 680.0
PYH2_k127_941886_1 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K17204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 589.0
PYH2_k127_941886_10 - - - - 0.00000000000000000000000000000000002687 137.0
PYH2_k127_941886_11 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000008863 126.0
PYH2_k127_941886_12 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000001262 112.0
PYH2_k127_941886_13 - - - - 0.00000008862 60.0
PYH2_k127_941886_14 membrane - - - 0.000000578 56.0
PYH2_k127_941886_15 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00003664 51.0
PYH2_k127_941886_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 533.0
PYH2_k127_941886_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 498.0
PYH2_k127_941886_4 ABC-type sugar transport system periplasmic component K10439,K17202,K17205,K17213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 406.0
PYH2_k127_941886_5 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 391.0
PYH2_k127_941886_6 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 322.0
PYH2_k127_941886_7 2-Keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 308.0
PYH2_k127_941886_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000004345 170.0
PYH2_k127_941886_9 RbsD / FucU transport protein family - - - 0.000000000000000000000000000000000000000004447 158.0
PYH2_k127_947430_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
PYH2_k127_947430_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000001213 104.0
PYH2_k127_959969_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.631e-264 819.0
PYH2_k127_959969_1 protein related to plant photosystem II stability assembly factor - - - 6.057e-214 670.0
PYH2_k127_959969_10 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000001682 253.0
PYH2_k127_959969_11 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003392 230.0
PYH2_k127_959969_12 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000000000001009 217.0
PYH2_k127_959969_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000473 209.0
PYH2_k127_959969_14 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000006557 181.0
PYH2_k127_959969_15 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000001288 183.0
PYH2_k127_959969_16 Involved in biosynthesis of extracellular polysaccharides - - - 0.0000000000000000000000000000000000000000000000003447 180.0
PYH2_k127_959969_17 ThiS family K03636 - - 0.000000000000000000000000000000001431 130.0
PYH2_k127_959969_18 membrane K08972 - - 0.00000000000000000000000000000003343 132.0
PYH2_k127_959969_19 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000003657 128.0
PYH2_k127_959969_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 567.0
PYH2_k127_959969_20 CoA-binding domain protein K09181 - - 0.000000000000000000000000000003153 136.0
PYH2_k127_959969_21 Endoribonuclease L-PSP - - - 0.0000000001218 66.0
PYH2_k127_959969_22 - - - - 0.00004861 51.0
PYH2_k127_959969_3 Soluble lytic murein K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 571.0
PYH2_k127_959969_4 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 416.0
PYH2_k127_959969_5 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 362.0
PYH2_k127_959969_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 294.0
PYH2_k127_959969_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 289.0
PYH2_k127_959969_8 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001123 284.0
PYH2_k127_959969_9 Glutathione S-transferase, N-terminal domain K11208 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
PYH2_k127_971365_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 325.0
PYH2_k127_971365_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002828 280.0
PYH2_k127_985818_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 510.0
PYH2_k127_985818_1 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 417.0
PYH2_k127_985818_2 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 367.0
PYH2_k127_985818_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002005 251.0
PYH2_k127_985818_4 rhamnose metabolic process - - - 0.000000000000000000000000000000006869 129.0
PYH2_k127_985818_5 - - - - 0.000000000000000000000002086 113.0
PYH2_k127_985818_6 AcrB/AcrD/AcrF family K03296,K18138,K18902 - - 0.00000000000000000000007051 99.0
PYH2_k127_985818_7 Protein of unknown function (DUF3303) - - - 0.00000000000000000000176 96.0