logo

Overview

ID MAG03175
Name PYH2_bin.15
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class UBA9217
Order UBA9217
Family UBA9217
Genus JAAXXJ01
Species
Assembly information
Completeness (%) 69.46
Contamination (%) 2.01
GC content (%) 60.0
N50 (bp) 5,635
Genome size (bp) 1,861,367

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1908

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_100364_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 362.0
PYH2_k127_100364_1 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
PYH2_k127_1020115_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 331.0
PYH2_k127_1020115_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH2_k127_1020115_3 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000001827 184.0
PYH2_k127_1020115_4 - - - - 0.000000000000000000000000000000000000000000008218 171.0
PYH2_k127_1020115_5 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000002566 125.0
PYH2_k127_1030345_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 306.0
PYH2_k127_1030345_1 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000005656 166.0
PYH2_k127_1030345_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000003568 139.0
PYH2_k127_1030345_3 Cellulose biosynthesis protein BcsQ K07321 - - 0.0002223 43.0
PYH2_k127_1034663_0 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 338.0
PYH2_k127_1034663_1 NADPH-quinone reductase (modulator of drug activity B) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 286.0
PYH2_k127_1034663_2 CGGC - - - 0.000000000000000000000000236 107.0
PYH2_k127_1034663_3 - - - - 0.00000000000003315 80.0
PYH2_k127_1100032_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.447e-207 667.0
PYH2_k127_1100032_1 Beta-propeller repeat - - - 0.0000000000001232 74.0
PYH2_k127_1111985_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 289.0
PYH2_k127_1111985_1 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005801 247.0
PYH2_k127_1111985_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000005205 215.0
PYH2_k127_1111985_3 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000005179 203.0
PYH2_k127_1111985_4 - - - - 0.00001158 53.0
PYH2_k127_1117725_0 transporter antisigma-factor antagonist STAS K03321 - - 1.874e-210 668.0
PYH2_k127_1117725_1 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000005445 204.0
PYH2_k127_1117725_2 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000367 153.0
PYH2_k127_1117725_3 - - - - 0.000000000000000000000000004803 110.0
PYH2_k127_1117725_5 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000001148 95.0
PYH2_k127_1117725_7 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000004678 91.0
PYH2_k127_1117725_8 Tetratricopeptide repeat - - - 0.00000002474 62.0
PYH2_k127_1121885_0 Peptidase M50 K16922 - - 9.156e-226 721.0
PYH2_k127_1121885_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 6.459e-220 700.0
PYH2_k127_1121885_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 509.0
PYH2_k127_1121885_3 Putative metallopeptidase - - - 0.00000000000000000001095 104.0
PYH2_k127_1121885_4 response regulator - - - 0.000000000157 69.0
PYH2_k127_1131979_0 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 322.0
PYH2_k127_1131979_1 Diguanylate cyclase - - - 0.00000000000000000001667 106.0
PYH2_k127_1148972_0 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000003333 229.0
PYH2_k127_1148972_1 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000001689 219.0
PYH2_k127_1148972_2 - - - - 0.0000000000000000000000001206 108.0
PYH2_k127_1148972_4 - - - - 0.000000000000008553 80.0
PYH2_k127_1170882_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1073.0
PYH2_k127_1170882_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 2.395e-206 657.0
PYH2_k127_1170882_2 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 604.0
PYH2_k127_1170882_3 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 489.0
PYH2_k127_1170882_4 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 474.0
PYH2_k127_1170882_5 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000004579 145.0
PYH2_k127_1170882_6 cyclic nucleotide-binding - - - 0.0000000000000000000000000000007301 130.0
PYH2_k127_1227659_0 TPR repeat - - - 1.473e-293 924.0
PYH2_k127_1227659_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 568.0
PYH2_k127_1227659_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 415.0
PYH2_k127_1227659_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 370.0
PYH2_k127_1227659_4 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001569 249.0
PYH2_k127_1227659_5 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000377 229.0
PYH2_k127_1227659_6 polysaccharide deacetylase K11931,K21478 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016787,GO:0016810,GO:0043170,GO:0043412,GO:0071704,GO:0098732 - 0.0000000000000000000000000000000000000000000000000002631 199.0
PYH2_k127_1227659_7 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000002225 80.0
PYH2_k127_1227659_8 Amidohydrolase family - - - 0.00000000000003306 78.0
PYH2_k127_1239238_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000008006 230.0
PYH2_k127_1239238_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000116 202.0
PYH2_k127_1239238_2 Tetratricopeptide repeat - - - 0.000000555 61.0
PYH2_k127_1264491_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 520.0
PYH2_k127_1264491_1 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 364.0
PYH2_k127_1264491_2 - - - - 0.00000000000000000000000000000000000000000000000000006315 189.0
PYH2_k127_1264491_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000007824 178.0
PYH2_k127_1264491_4 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000000000002136 158.0
PYH2_k127_1264491_5 - - - - 0.0000000000000000000000000001449 122.0
PYH2_k127_1264491_6 - - - - 0.000000000000000000000000003996 114.0
PYH2_k127_1281528_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002696 241.0
PYH2_k127_1300604_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 574.0
PYH2_k127_1300604_1 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000000002108 186.0
PYH2_k127_1300604_2 - - - - 0.0000000000000000000000000000000000000000006409 161.0
PYH2_k127_1300604_3 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000002653 118.0
PYH2_k127_1300604_4 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000003964 103.0
PYH2_k127_1300604_5 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.0000000000000000006117 92.0
PYH2_k127_1300604_6 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule K00158 - 1.2.3.3 0.0000000000001795 71.0
PYH2_k127_1300604_8 Flavin reductase like domain - - - 0.000004301 56.0
PYH2_k127_1307086_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.975e-306 945.0
PYH2_k127_1307086_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.921e-254 812.0
PYH2_k127_1307086_10 PFAM thiamineS protein - - - 0.00000000004012 66.0
PYH2_k127_1307086_12 - - - - 0.00000173 57.0
PYH2_k127_1307086_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 491.0
PYH2_k127_1307086_3 PFAM MltA K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 342.0
PYH2_k127_1307086_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004407 256.0
PYH2_k127_1307086_5 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004107 254.0
PYH2_k127_1307086_6 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001267 219.0
PYH2_k127_1307086_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000001076 223.0
PYH2_k127_1307086_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000001215 209.0
PYH2_k127_1307086_9 - - - - 0.0000000000000000000000000000003284 131.0
PYH2_k127_1456780_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 558.0
PYH2_k127_1456780_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
PYH2_k127_1456780_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000001613 223.0
PYH2_k127_1456780_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.000000000003094 68.0
PYH2_k127_1458804_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000004748 238.0
PYH2_k127_1458804_1 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000001397 214.0
PYH2_k127_1473670_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 451.0
PYH2_k127_1473670_1 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000002037 166.0
PYH2_k127_1481547_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 284.0
PYH2_k127_1481547_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005861 291.0
PYH2_k127_1481547_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000002265 147.0
PYH2_k127_1525068_0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000007721 219.0
PYH2_k127_1525068_1 Histidine kinase K02660,K11525 - - 0.00000000000000000000000000000000159 137.0
PYH2_k127_1537524_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000263 198.0
PYH2_k127_1537524_1 Putative zinc-finger - - - 0.0000000000000007413 90.0
PYH2_k127_1537524_2 PFAM Isochorismatase - - - 0.000000000000002892 79.0
PYH2_k127_156808_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 303.0
PYH2_k127_156808_1 ferredoxin-thioredoxin reductase activity - - - 0.00000000000000000000000000000000000000002439 154.0
PYH2_k127_156808_2 Immunity protein 35 - - - 0.00000000000000000000000000000000000003051 145.0
PYH2_k127_156808_3 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000001788 139.0
PYH2_k127_156808_4 PFAM Glutaredoxin K06191 - - 0.000000000000000000001109 98.0
PYH2_k127_156808_6 COG4670 Acyl CoA acetate 3-ketoacid CoA transferase K13929 - 2.3.1.187 0.0000009973 51.0
PYH2_k127_164429_0 Protein of unknown function (DUF3604) - - - 2.018e-312 971.0
PYH2_k127_164429_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 339.0
PYH2_k127_164429_2 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000151 231.0
PYH2_k127_164429_3 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000021 224.0
PYH2_k127_164429_4 HupE / UreJ protein - - - 0.0000000000000000000000000000000005218 144.0
PYH2_k127_164429_5 Mechanosensitive ion channel K16052 - - 0.000000000002812 73.0
PYH2_k127_164429_6 Rhodanese Homology Domain - - - 0.00001613 53.0
PYH2_k127_164429_7 - - - - 0.0004391 44.0
PYH2_k127_1843326_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 1.228e-220 710.0
PYH2_k127_1843326_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 451.0
PYH2_k127_1843326_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000002576 208.0
PYH2_k127_1843326_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000001876 128.0
PYH2_k127_1843326_4 RNA recognition motif - - - 0.00000000000000000000000001189 113.0
PYH2_k127_1843326_5 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001163 64.0
PYH2_k127_1868314_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 365.0
PYH2_k127_1868314_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 344.0
PYH2_k127_1868314_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
PYH2_k127_1868314_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000003625 184.0
PYH2_k127_1868314_4 metalloendopeptidase activity K03799 - - 0.000000000000000000000001537 114.0
PYH2_k127_188990_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
PYH2_k127_188990_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000002293 166.0
PYH2_k127_188990_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000009792 164.0
PYH2_k127_188990_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000002001 138.0
PYH2_k127_188990_4 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.000001373 50.0
PYH2_k127_1892037_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 540.0
PYH2_k127_1892037_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000002661 133.0
PYH2_k127_1892037_2 sulfur carrier activity - - - 0.00000000000000000000006477 100.0
PYH2_k127_1892037_3 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000003226 75.0
PYH2_k127_1906221_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000002311 231.0
PYH2_k127_1906221_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000001511 163.0
PYH2_k127_1906221_2 mttA/Hcf106 family K03116 - - 0.000000000009172 68.0
PYH2_k127_1916325_0 membrane organization K20543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000515 267.0
PYH2_k127_1916325_1 CGGC - - - 0.0000000000000000000000000000000000000000000000005909 177.0
PYH2_k127_1920948_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 441.0
PYH2_k127_1920948_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000001215 224.0
PYH2_k127_1920948_2 ACT domain - - - 0.000000000000000000000000000000000000000000000000001139 190.0
PYH2_k127_1933584_0 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 559.0
PYH2_k127_1933584_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000001215 163.0
PYH2_k127_1942520_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.799e-204 649.0
PYH2_k127_1942520_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 380.0
PYH2_k127_1942520_2 Thioredoxin reductase K00384 - 1.8.1.9 0.000000000000000000000000009617 115.0
PYH2_k127_1944304_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 377.0
PYH2_k127_1944304_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000004414 191.0
PYH2_k127_1944304_2 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000003399 81.0
PYH2_k127_1952401_0 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 459.0
PYH2_k127_1952401_1 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000002356 183.0
PYH2_k127_1959179_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000005567 130.0
PYH2_k127_1959179_1 SnoaL-like domain - - - 0.0000000000000000000000006435 106.0
PYH2_k127_1978322_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007396 244.0
PYH2_k127_1978322_1 PFAM PHP domain - - - 0.00000000000000000000000000000000000000003452 160.0
PYH2_k127_1978322_2 - - - - 0.0000000000000000000000000000000000000002311 158.0
PYH2_k127_1978322_3 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.0000000000000000000000000000001048 128.0
PYH2_k127_1978322_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000006679 118.0
PYH2_k127_1978322_5 Protein of unknown function (DUF2892) - - - 0.000000000000000000000003774 103.0
PYH2_k127_1978322_6 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000003275 106.0
PYH2_k127_1978322_7 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000005732 86.0
PYH2_k127_1978322_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000002996 87.0
PYH2_k127_1978322_9 response regulator, receiver - - - 0.00003131 54.0
PYH2_k127_1985039_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 372.0
PYH2_k127_1985039_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 291.0
PYH2_k127_1985039_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
PYH2_k127_1985039_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000002118 199.0
PYH2_k127_1985039_4 YGGT family K02221 - - 0.00000000000000000000000000003864 120.0
PYH2_k127_1985039_5 DivIVA protein K04074 - - 0.0000000000000000000000000001181 120.0
PYH2_k127_1986890_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 599.0
PYH2_k127_1986890_1 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 510.0
PYH2_k127_1986890_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 497.0
PYH2_k127_1986890_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 441.0
PYH2_k127_1986890_4 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 327.0
PYH2_k127_1986890_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
PYH2_k127_1986890_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001314 259.0
PYH2_k127_1986890_7 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000004187 243.0
PYH2_k127_1986890_8 translation initiation factor activity - - - 0.00000000000000000000000000000004725 135.0
PYH2_k127_1987227_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000005412 156.0
PYH2_k127_1987227_2 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000000003377 122.0
PYH2_k127_1987227_3 carboxymuconolactone decarboxylase - - - 0.000000001964 59.0
PYH2_k127_1987227_4 carboxymuconolactone decarboxylase K07486 - - 0.00001962 51.0
PYH2_k127_2003380_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 295.0
PYH2_k127_2003380_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000002076 210.0
PYH2_k127_2003380_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000003289 154.0
PYH2_k127_2003380_3 NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000002052 112.0
PYH2_k127_2013578_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.714e-201 640.0
PYH2_k127_2013578_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001591 235.0
PYH2_k127_2013578_2 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000008241 188.0
PYH2_k127_2013578_3 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000000000000002392 154.0
PYH2_k127_2013578_4 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000003528 119.0
PYH2_k127_2013578_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000117 106.0
PYH2_k127_2013578_6 Domain of unknown function (DUF4253) - - - 0.00000000000008114 81.0
PYH2_k127_2027596_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 287.0
PYH2_k127_2027596_1 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
PYH2_k127_2027596_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH2_k127_2027596_3 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.00000000000000000000000000000000000000007028 154.0
PYH2_k127_2027596_4 binding domain protein - - - 0.00000000000000000000000000000000009536 136.0
PYH2_k127_2027596_5 part of a sulfur-relay system K11179 - - 0.0000000000000000000000006636 108.0
PYH2_k127_2042809_0 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
PYH2_k127_2042809_1 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000002703 145.0
PYH2_k127_2042809_2 - - - - 0.00000000000000000000000000000001161 134.0
PYH2_k127_2042809_3 - - - - 0.0000000000000000005895 94.0
PYH2_k127_2042809_4 - - - - 0.000000000000001236 85.0
PYH2_k127_2042809_5 - - - - 0.00000005261 62.0
PYH2_k127_2053961_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 8.214e-198 629.0
PYH2_k127_2053961_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 535.0
PYH2_k127_2053961_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 359.0
PYH2_k127_2053961_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 352.0
PYH2_k127_2053961_4 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000316 213.0
PYH2_k127_2053961_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000001105 190.0
PYH2_k127_2053961_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000001245 127.0
PYH2_k127_2053961_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000001491 124.0
PYH2_k127_2053961_8 Phosphate starvation-inducible protein PhoH K06217 - - 0.00001726 51.0
PYH2_k127_2054915_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 432.0
PYH2_k127_2054915_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000006272 145.0
PYH2_k127_2054915_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000306 130.0
PYH2_k127_2054915_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000002632 52.0
PYH2_k127_2067558_0 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 314.0
PYH2_k127_2067558_1 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000002323 194.0
PYH2_k127_2067558_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000422 145.0
PYH2_k127_2067558_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.000000000000000000000004627 106.0
PYH2_k127_208888_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1139.0
PYH2_k127_208888_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.369e-250 797.0
PYH2_k127_208888_10 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000001013 205.0
PYH2_k127_208888_11 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000002464 192.0
PYH2_k127_208888_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000005939 135.0
PYH2_k127_208888_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000002968 124.0
PYH2_k127_208888_14 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.00000000000000000000000002407 115.0
PYH2_k127_208888_15 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000004671 108.0
PYH2_k127_208888_16 Hypothetical glycosyl hydrolase family 13 K11931 - - 0.00000128 60.0
PYH2_k127_208888_17 unfolded protein binding K06142 - - 0.000001979 57.0
PYH2_k127_208888_18 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0005807 52.0
PYH2_k127_208888_2 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.234e-249 786.0
PYH2_k127_208888_3 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 510.0
PYH2_k127_208888_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 331.0
PYH2_k127_208888_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 301.0
PYH2_k127_208888_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007661 280.0
PYH2_k127_208888_7 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000009105 255.0
PYH2_k127_208888_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000007186 248.0
PYH2_k127_208888_9 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH2_k127_2100850_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000001674 170.0
PYH2_k127_2100850_1 cheY-homologous receiver domain - - - 0.000004393 57.0
PYH2_k127_2114335_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 406.0
PYH2_k127_2114335_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 365.0
PYH2_k127_2114335_2 PFAM methyltransferase small K15460 - 2.1.1.223 0.00000000000000000000000000000000000000002725 165.0
PYH2_k127_2114335_3 Aminotransferase - - - 0.00000000000000000000000000000000000000545 147.0
PYH2_k127_2114335_4 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000001137 128.0
PYH2_k127_2114335_5 Protein of unknown function (DUF721) - - - 0.000000000000000000001964 99.0
PYH2_k127_2126700_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004518 280.0
PYH2_k127_2126700_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000003823 267.0
PYH2_k127_2126700_2 Smr domain - - - 0.00000000000000000000000000000000007713 141.0
PYH2_k127_2126700_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000009187 138.0
PYH2_k127_2126700_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000007287 118.0
PYH2_k127_2126700_5 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000003392 114.0
PYH2_k127_2126700_6 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000001382 100.0
PYH2_k127_2138154_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 430.0
PYH2_k127_2138154_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000004628 232.0
PYH2_k127_2138154_2 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000003425 209.0
PYH2_k127_2138154_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000001172 108.0
PYH2_k127_2138154_4 ATPase involved in DNA repair - - - 0.00000000001205 78.0
PYH2_k127_2139068_0 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 295.0
PYH2_k127_2139068_1 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000004239 235.0
PYH2_k127_2139068_2 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000308 188.0
PYH2_k127_2139068_3 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000003554 168.0
PYH2_k127_2139068_4 OmpA family K02557 - - 0.000000000000000000000000000000004211 141.0
PYH2_k127_2139068_5 cobalt ion transport K02009 - - 0.0000000000000000000000000002769 119.0
PYH2_k127_2143662_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 447.0
PYH2_k127_2143662_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000593 134.0
PYH2_k127_2144357_0 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
PYH2_k127_2144357_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 263.0
PYH2_k127_2144357_10 PFAM amino acid-binding ACT domain protein - - - 0.0000003125 60.0
PYH2_k127_2144357_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000254 246.0
PYH2_k127_2144357_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 256.0
PYH2_k127_2144357_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
PYH2_k127_2144357_5 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000003262 177.0
PYH2_k127_2144357_7 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000465 128.0
PYH2_k127_2144357_8 - - - - 0.000000000000000002558 93.0
PYH2_k127_2144357_9 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000008379 74.0
PYH2_k127_2151402_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 391.0
PYH2_k127_2151402_1 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 325.0
PYH2_k127_2151402_2 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003717 286.0
PYH2_k127_21838_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000002846 203.0
PYH2_k127_21838_1 Part of a membrane complex involved in electron transport K03612 - - 0.0000139 52.0
PYH2_k127_2221604_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 437.0
PYH2_k127_2221604_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000005374 239.0
PYH2_k127_2221753_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 323.0
PYH2_k127_2221753_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000216 240.0
PYH2_k127_2221753_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000962 162.0
PYH2_k127_2221753_3 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.00000000000000000000000000000009819 126.0
PYH2_k127_2222485_0 L-glutamate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 387.0
PYH2_k127_2222485_1 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 324.0
PYH2_k127_2253070_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2055.0
PYH2_k127_2253070_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1390.0
PYH2_k127_2253070_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1051.0
PYH2_k127_2253070_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000003048 229.0
PYH2_k127_2253070_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
PYH2_k127_2253070_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000008689 80.0
PYH2_k127_2257006_0 PFAM sulfatase K01130 - 3.1.6.1 4.85e-229 722.0
PYH2_k127_2257006_1 Domain of unknown function (DUF4823) - - - 0.000000000000000000000000000000000000000000000000000001234 196.0
PYH2_k127_2260288_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 583.0
PYH2_k127_2260288_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001726 284.0
PYH2_k127_2260288_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000001326 205.0
PYH2_k127_2260288_3 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000008433 181.0
PYH2_k127_2260288_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000001378 114.0
PYH2_k127_2260288_5 KR domain K00059 - 1.1.1.100 0.0000000000000005603 78.0
PYH2_k127_2330360_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 395.0
PYH2_k127_2330360_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002553 287.0
PYH2_k127_2333174_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 499.0
PYH2_k127_2333174_1 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 398.0
PYH2_k127_2333174_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000007109 165.0
PYH2_k127_2343878_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 338.0
PYH2_k127_2343878_1 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 339.0
PYH2_k127_2343878_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
PYH2_k127_2343878_3 S4 domain protein - - - 0.000000000000005159 83.0
PYH2_k127_2391664_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000001679 269.0
PYH2_k127_2391664_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000003585 74.0
PYH2_k127_2391664_3 ABC1 family - - - 0.00000000003904 68.0
PYH2_k127_2391664_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000005779 57.0
PYH2_k127_2405574_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 437.0
PYH2_k127_2405574_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 403.0
PYH2_k127_2405574_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000003063 238.0
PYH2_k127_2405574_3 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000004867 139.0
PYH2_k127_24159_0 PFAM Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 531.0
PYH2_k127_24159_1 fibronectin type III domain protein K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 396.0
PYH2_k127_24159_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000002683 76.0
PYH2_k127_242309_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 580.0
PYH2_k127_242309_1 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 542.0
PYH2_k127_242309_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 532.0
PYH2_k127_242309_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
PYH2_k127_242309_4 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000001605 161.0
PYH2_k127_242309_5 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000007711 113.0
PYH2_k127_242309_6 COG NOG19146 non supervised orthologous group - - - 0.000001229 52.0
PYH2_k127_242309_7 Protein of unknown function (DUF1573) - - - 0.00008835 48.0
PYH2_k127_2441776_0 DNA topoisomerase II activity K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 610.0
PYH2_k127_2441776_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
PYH2_k127_2441776_2 HD domain - - - 0.00000000000000000000000000000000000000000001044 178.0
PYH2_k127_2441776_4 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000761 63.0
PYH2_k127_2441776_5 sigma factor antagonist activity K04757 - 2.7.11.1 0.000001065 61.0
PYH2_k127_2498938_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 501.0
PYH2_k127_255013_0 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 437.0
PYH2_k127_255013_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
PYH2_k127_255013_2 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000003888 141.0
PYH2_k127_255013_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000018 106.0
PYH2_k127_255013_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K01817 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 0.00000004457 54.0
PYH2_k127_261774_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 405.0
PYH2_k127_261774_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 307.0
PYH2_k127_261774_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000001985 110.0
PYH2_k127_2620336_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.924e-280 874.0
PYH2_k127_2620336_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000006742 266.0
PYH2_k127_2620336_2 TIGRFAM MATE efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000001625 218.0
PYH2_k127_2620336_3 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000001198 117.0
PYH2_k127_2692578_0 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 577.0
PYH2_k127_2692578_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 287.0
PYH2_k127_2692578_2 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000004007 119.0
PYH2_k127_2692578_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000002568 118.0
PYH2_k127_2692578_4 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001016 98.0
PYH2_k127_2722047_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 466.0
PYH2_k127_2722047_1 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 357.0
PYH2_k127_2722047_2 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 337.0
PYH2_k127_2722047_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000001802 138.0
PYH2_k127_275065_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 5.883e-256 798.0
PYH2_k127_2798305_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 342.0
PYH2_k127_2798305_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 320.0
PYH2_k127_2798305_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000001496 199.0
PYH2_k127_2798305_3 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.0000000000000000000000000000000000000000000000000000002104 205.0
PYH2_k127_2803187_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 476.0
PYH2_k127_2803187_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 434.0
PYH2_k127_2803187_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
PYH2_k127_2803187_3 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000002672 186.0
PYH2_k127_2803187_4 RF-1 domain - - - 0.00000000000000000000000008983 113.0
PYH2_k127_2814329_0 SMART Elongator protein 3 MiaB NifB - - - 3.652e-205 657.0
PYH2_k127_2814329_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000002896 168.0
PYH2_k127_2814329_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000008331 113.0
PYH2_k127_2822790_0 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 614.0
PYH2_k127_2822790_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 486.0
PYH2_k127_2822790_2 Capsule polysaccharide biosynthesis protein K07265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 482.0
PYH2_k127_2822790_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006,K22424 - 2.7.3.13,2.7.9.1 0.000000000000000000000000001809 114.0
PYH2_k127_2822790_5 Involved in the biosynthesis of a cell envelope polysaccharide, possibly a capsular polysaccharide CPS K07266 - - 0.0000000000000000003432 89.0
PYH2_k127_2835651_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.395e-234 731.0
PYH2_k127_2835651_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 314.0
PYH2_k127_2835651_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
PYH2_k127_2835651_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000006221 225.0
PYH2_k127_2835651_4 YbbR-like protein - - - 0.0000000000000000000000000000000005408 139.0
PYH2_k127_2842493_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 3.493e-197 628.0
PYH2_k127_2842493_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000002529 214.0
PYH2_k127_2842493_2 cyclic nucleotide binding K10914 - - 0.0000000000000000000000007279 106.0
PYH2_k127_2861758_0 CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 422.0
PYH2_k127_2861758_1 Major facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 340.0
PYH2_k127_2861758_2 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001526 248.0
PYH2_k127_2861758_3 BadF BadG BcrA BcrD - - - 0.000000000000685 74.0
PYH2_k127_2861758_4 phosphorelay signal transduction system - - - 0.000000003855 66.0
PYH2_k127_2878062_0 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 434.0
PYH2_k127_2878062_1 PFAM glycosyl transferase, family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 317.0
PYH2_k127_2878062_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000009455 85.0
PYH2_k127_2878062_3 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000738 72.0
PYH2_k127_2891951_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 500.0
PYH2_k127_2891951_1 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 379.0
PYH2_k127_2891951_2 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 323.0
PYH2_k127_2891951_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001663 282.0
PYH2_k127_2891951_4 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 261.0
PYH2_k127_2891951_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000007083 187.0
PYH2_k127_2891951_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000009307 115.0
PYH2_k127_2891951_7 MlaD protein K02067 - - 0.00000000000000000000000006511 118.0
PYH2_k127_2891951_8 antisigma factor binding K04749 - - 0.000000000000003279 80.0
PYH2_k127_2891951_9 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000008568 62.0
PYH2_k127_289314_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 487.0
PYH2_k127_289314_1 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 337.0
PYH2_k127_289314_2 PFAM Rhodanese-like - - - 0.0000000000000000004391 89.0
PYH2_k127_289314_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000002375 81.0
PYH2_k127_289314_4 Putative regulatory protein - - - 0.000004514 51.0
PYH2_k127_2897819_0 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
PYH2_k127_2897819_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000333 156.0
PYH2_k127_2913993_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 595.0
PYH2_k127_2913993_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000002297 241.0
PYH2_k127_2913993_2 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 246.0
PYH2_k127_2913993_3 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
PYH2_k127_2913993_4 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000005703 152.0
PYH2_k127_2913993_5 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000003556 144.0
PYH2_k127_2913993_6 Cysteine-rich small domain K07162 - - 0.00000000000000000000001273 103.0
PYH2_k127_2913993_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.0000000001223 71.0
PYH2_k127_2929611_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1009.0
PYH2_k127_2929611_1 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000003202 91.0
PYH2_k127_2929611_2 DNA polymerase III (delta' subunit) K02340 - 2.7.7.7 0.00000000000005093 75.0
PYH2_k127_2931991_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000003634 124.0
PYH2_k127_2931991_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000002379 98.0
PYH2_k127_2931991_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00004517 49.0
PYH2_k127_2968033_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 594.0
PYH2_k127_2968033_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 504.0
PYH2_k127_2968033_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009064 294.0
PYH2_k127_2968033_3 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007222 276.0
PYH2_k127_2968033_4 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.0000000000007549 70.0
PYH2_k127_2980300_0 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 385.0
PYH2_k127_2980300_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004602 270.0
PYH2_k127_2980300_2 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000001457 177.0
PYH2_k127_2980300_3 denitrification pathway - - - 0.000000000000000000000000000000000009444 143.0
PYH2_k127_2980300_5 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000009058 70.0
PYH2_k127_2993185_0 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001796 254.0
PYH2_k127_2993185_1 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001431 196.0
PYH2_k127_2993185_2 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000009402 145.0
PYH2_k127_2998814_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 572.0
PYH2_k127_2998814_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 394.0
PYH2_k127_2998814_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
PYH2_k127_2998814_3 DNA ligase K01971 - 6.5.1.1 0.000000000000009246 74.0
PYH2_k127_2998814_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000005097 53.0
PYH2_k127_302007_0 GMC oxidoreductase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 1.243e-214 679.0
PYH2_k127_302007_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 322.0
PYH2_k127_302007_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 299.0
PYH2_k127_302007_3 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005976 272.0
PYH2_k127_302007_4 Phospholipase D Transphosphatidylase K06132 - - 0.00000000000000000000000000000001547 131.0
PYH2_k127_302463_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 5.521e-234 734.0
PYH2_k127_302463_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 357.0
PYH2_k127_302463_10 CutA1 divalent ion tolerance protein K01733,K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 4.2.3.1 0.0000000000000000000000000008767 115.0
PYH2_k127_302463_11 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000001916 112.0
PYH2_k127_302463_12 Methyltransferase type 11 - - - 0.00000000000000000000000587 103.0
PYH2_k127_302463_13 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000002282 100.0
PYH2_k127_302463_14 Sporulation and spore germination - - - 0.000000000000002903 83.0
PYH2_k127_302463_15 Ami_3 K01448 - 3.5.1.28 0.0000000001056 73.0
PYH2_k127_302463_16 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000003703 63.0
PYH2_k127_302463_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 323.0
PYH2_k127_302463_3 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 306.0
PYH2_k127_302463_4 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001063 251.0
PYH2_k127_302463_5 - K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
PYH2_k127_302463_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000135 215.0
PYH2_k127_302463_7 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000002978 220.0
PYH2_k127_302463_8 - K07112 - - 0.0000000000000000000000000000000000000000000000000003421 193.0
PYH2_k127_302463_9 - - - - 0.00000000000000000000000000004642 119.0
PYH2_k127_3072334_0 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000001263 169.0
PYH2_k127_3072334_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000001255 126.0
PYH2_k127_3072334_2 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.99.3 0.0003054 47.0
PYH2_k127_3124451_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000001664 237.0
PYH2_k127_3124451_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
PYH2_k127_3131435_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.823e-247 773.0
PYH2_k127_3131435_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 495.0
PYH2_k127_3131435_2 - - - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
PYH2_k127_3133946_0 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 330.0
PYH2_k127_3133946_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 309.0
PYH2_k127_3184848_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 420.0
PYH2_k127_3184848_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 293.0
PYH2_k127_3184848_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 244.0
PYH2_k127_3184848_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000248 127.0
PYH2_k127_3184848_4 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000003541 84.0
PYH2_k127_319590_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 438.0
PYH2_k127_319590_1 PFAM Cupin - - - 0.000000000000000000000000000000000000000000006766 166.0
PYH2_k127_319590_2 'Cold-shock' DNA-binding domain K03704 - - 0.0000000001397 64.0
PYH2_k127_319590_3 PFAM Transposase IS200 like K07491 - - 0.0009522 42.0
PYH2_k127_321405_0 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 574.0
PYH2_k127_321405_1 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000002204 176.0
PYH2_k127_321405_3 - - - - 0.000000009192 57.0
PYH2_k127_3234572_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 397.0
PYH2_k127_3234572_1 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000002075 215.0
PYH2_k127_3234572_2 Tetratricopeptide repeat protein - - - 0.0000002981 59.0
PYH2_k127_325355_0 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000002237 216.0
PYH2_k127_325355_1 regulation of translation K03530 - - 0.0000000000000000000000000000000000009007 141.0
PYH2_k127_325355_2 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000005401 143.0
PYH2_k127_325355_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000002076 111.0
PYH2_k127_325355_4 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000005598 108.0
PYH2_k127_325355_5 - - - - 0.00000004816 58.0
PYH2_k127_325355_6 PFAM Outer membrane lipoprotein Slp K07285 - - 0.00001302 52.0
PYH2_k127_326599_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 501.0
PYH2_k127_326599_1 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 286.0
PYH2_k127_326599_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000002282 164.0
PYH2_k127_326599_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000002998 121.0
PYH2_k127_326599_4 PFAM pyridoxamine 5-phosphate - - - 0.00000000000000000000000000001708 121.0
PYH2_k127_3266024_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 404.0
PYH2_k127_3266024_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 340.0
PYH2_k127_3266024_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009703 280.0
PYH2_k127_3266024_3 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000003337 231.0
PYH2_k127_3266024_4 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000000000000000000000000000001321 230.0
PYH2_k127_3266024_6 PFAM Major Facilitator Superfamily K08177 - - 0.000000000002068 68.0
PYH2_k127_3279083_0 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 378.0
PYH2_k127_3279083_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007329 280.0
PYH2_k127_3279083_2 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000000000000000000000000000000000000000000000002222 211.0
PYH2_k127_3279083_4 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000000000004255 78.0
PYH2_k127_3279083_5 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00008505 48.0
PYH2_k127_3357899_0 Bacterial trigger factor protein (TF) C-terminus K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000007128 259.0
PYH2_k127_3357899_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000003533 162.0
PYH2_k127_3357899_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000009479 83.0
PYH2_k127_3358094_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 302.0
PYH2_k127_3358094_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000004812 186.0
PYH2_k127_3358094_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000238 162.0
PYH2_k127_3378895_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 3.68e-246 784.0
PYH2_k127_3378895_1 Cytochrome oxidase maturation protein - - - 0.000000000001202 73.0
PYH2_k127_3378895_2 Bacterial regulatory proteins, tetR family - - - 0.000000000002954 72.0
PYH2_k127_3413912_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002721 291.0
PYH2_k127_3422447_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 388.0
PYH2_k127_3422447_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000008043 209.0
PYH2_k127_34496_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
PYH2_k127_34496_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 306.0
PYH2_k127_34496_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007371 286.0
PYH2_k127_34496_3 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000001835 174.0
PYH2_k127_34496_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000002957 132.0
PYH2_k127_34496_5 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000004658 104.0
PYH2_k127_3482196_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.65e-197 622.0
PYH2_k127_3482196_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000001463 143.0
PYH2_k127_3542971_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000272 190.0
PYH2_k127_3542971_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000001305 141.0
PYH2_k127_3579948_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 582.0
PYH2_k127_3579948_1 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 303.0
PYH2_k127_3579948_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000734 151.0
PYH2_k127_3713589_0 Major facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 364.0
PYH2_k127_3713589_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000002074 177.0
PYH2_k127_3713589_2 - - - - 0.000000000000004438 83.0
PYH2_k127_3735413_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 442.0
PYH2_k127_3736444_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000005951 113.0
PYH2_k127_3736444_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00005813 55.0
PYH2_k127_3745042_0 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000004483 147.0
PYH2_k127_3745042_1 Domain of unknown function (DUF1844) - - - 0.00000000000000000001782 99.0
PYH2_k127_3745042_2 CbiX K03794,K03795 - 4.99.1.3,4.99.1.4 0.000000000000004059 83.0
PYH2_k127_3745042_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000004224 61.0
PYH2_k127_3745252_0 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 352.0
PYH2_k127_3745252_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 340.0
PYH2_k127_3745252_2 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 301.0
PYH2_k127_3745252_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004279 271.0
PYH2_k127_3745252_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
PYH2_k127_3745252_5 Peptide nickel ABC transporter, permease K02034 - - 0.0000000000000000000000000000000000000000000000002396 192.0
PYH2_k127_3745252_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000007937 131.0
PYH2_k127_3745252_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000006038 85.0
PYH2_k127_3745259_0 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009001 267.0
PYH2_k127_3745259_1 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000002571 193.0
PYH2_k127_3745259_2 - - - - 0.00000000000000000008215 92.0
PYH2_k127_3749972_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
PYH2_k127_3749972_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 298.0
PYH2_k127_3749972_2 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000001448 209.0
PYH2_k127_3749972_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000004569 206.0
PYH2_k127_3749972_4 - - - - 0.000000000000000000003969 98.0
PYH2_k127_3749972_5 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000003744 61.0
PYH2_k127_378977_0 PFAM NLP P60 protein - - - 0.00000000000000000000000000002186 123.0
PYH2_k127_378977_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000008112 114.0
PYH2_k127_3807875_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000002846 142.0
PYH2_k127_3807875_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000003073 126.0
PYH2_k127_3807875_2 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000001146 118.0
PYH2_k127_3814197_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 582.0
PYH2_k127_3814197_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 497.0
PYH2_k127_3814197_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
PYH2_k127_3814197_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
PYH2_k127_3814197_4 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000001644 125.0
PYH2_k127_3818_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 562.0
PYH2_k127_3818_1 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 338.0
PYH2_k127_3823276_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 559.0
PYH2_k127_3823276_1 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000222 217.0
PYH2_k127_3823276_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000001573 215.0
PYH2_k127_3823276_3 4Fe-4S binding domain K08358 - - 0.00000000000005954 71.0
PYH2_k127_3861531_0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004536 252.0
PYH2_k127_3861531_1 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000003996 132.0
PYH2_k127_3861531_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000156 124.0
PYH2_k127_3862142_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000004142 195.0
PYH2_k127_3862142_1 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000001832 109.0
PYH2_k127_3862142_2 - - - - 0.0000000000000001839 84.0
PYH2_k127_3862142_3 chemotaxis K03406 - - 0.000000005398 60.0
PYH2_k127_3906917_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000002586 204.0
PYH2_k127_3906917_1 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000000005827 146.0
PYH2_k127_3906917_2 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000001944 121.0
PYH2_k127_3906917_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000137 88.0
PYH2_k127_3906917_4 - - - - 0.00000113 52.0
PYH2_k127_3921292_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 520.0
PYH2_k127_3921292_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 402.0
PYH2_k127_3921292_2 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00000000000000000000000000000008518 132.0
PYH2_k127_392185_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 522.0
PYH2_k127_392185_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 388.0
PYH2_k127_3950604_0 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 388.0
PYH2_k127_3950604_1 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 329.0
PYH2_k127_3950604_2 Protein of unknown function (DUF3187) - - - 0.00000000000000000000004058 111.0
PYH2_k127_3950604_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000009783 91.0
PYH2_k127_3950604_4 - - - - 0.0000000000000003276 84.0
PYH2_k127_3950604_5 GYD domain - - - 0.0000000005708 62.0
PYH2_k127_3950604_6 Predicted RNA-binding protein - - - 0.00000001312 58.0
PYH2_k127_3961908_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 291.0
PYH2_k127_3961908_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000005331 194.0
PYH2_k127_3961908_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000006704 158.0
PYH2_k127_3967299_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 582.0
PYH2_k127_3967299_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 352.0
PYH2_k127_3967299_10 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000002742 78.0
PYH2_k127_3967299_2 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 309.0
PYH2_k127_3967299_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008969 284.0
PYH2_k127_3967299_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
PYH2_k127_3967299_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000155 193.0
PYH2_k127_3967299_6 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000000000001691 136.0
PYH2_k127_3967299_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000418 101.0
PYH2_k127_3967299_8 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000613 89.0
PYH2_k127_3967299_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000000001839 84.0
PYH2_k127_4016008_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.581e-268 844.0
PYH2_k127_4016008_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 4.55e-258 812.0
PYH2_k127_4016008_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001013 244.0
PYH2_k127_4016008_3 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000001546 189.0
PYH2_k127_4016008_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000004867 143.0
PYH2_k127_4041307_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 410.0
PYH2_k127_4041307_1 protein conserved in bacteria K09798 - - 0.0000000000000000000000000000000000000000000000000205 192.0
PYH2_k127_4054822_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 581.0
PYH2_k127_4054822_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 399.0
PYH2_k127_4054822_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 374.0
PYH2_k127_4054822_3 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 313.0
PYH2_k127_4054822_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 290.0
PYH2_k127_4054822_5 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000002022 238.0
PYH2_k127_4054822_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000245 194.0
PYH2_k127_4054822_7 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000001572 167.0
PYH2_k127_4061477_0 CBS domain containing protein K00974 - 2.7.7.72 1.067e-200 646.0
PYH2_k127_4061477_1 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 396.0
PYH2_k127_4061477_2 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000013 220.0
PYH2_k127_4061477_3 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000002882 186.0
PYH2_k127_4061477_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000004603 120.0
PYH2_k127_4079518_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 5.497e-228 719.0
PYH2_k127_4079518_1 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.0000000000000000008594 89.0
PYH2_k127_4119974_0 cog0421, spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001653 261.0
PYH2_k127_4119974_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000001423 155.0
PYH2_k127_4119974_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000008753 159.0
PYH2_k127_4119974_3 - K07112 - - 0.000000000000000000000000000000002324 140.0
PYH2_k127_4142953_0 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 360.0
PYH2_k127_4142953_1 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000005194 193.0
PYH2_k127_4142953_2 PFAM EAL domain protein - - - 0.00000000000000000008976 92.0
PYH2_k127_4146345_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.823e-211 676.0
PYH2_k127_4146345_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000009934 250.0
PYH2_k127_4146345_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000009343 128.0
PYH2_k127_4146345_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000107 113.0
PYH2_k127_4146345_4 TIGRFAM regulatory protein, FmdB - - - 0.00000000004079 67.0
PYH2_k127_4165407_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 404.0
PYH2_k127_4165407_1 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000000000000000000000002107 139.0
PYH2_k127_4165407_2 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000001016 100.0
PYH2_k127_42708_0 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000003061 187.0
PYH2_k127_42708_1 - - - - 0.0000000000000000000000000000000000000000000000002707 188.0
PYH2_k127_42708_2 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000011 166.0
PYH2_k127_42708_3 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000005319 109.0
PYH2_k127_42708_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000751 70.0
PYH2_k127_428403_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 335.0
PYH2_k127_428403_1 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000004338 231.0
PYH2_k127_4300157_0 zinc ion binding K12035 - 2.3.2.27 0.000000000000000000000316 113.0
PYH2_k127_4300157_1 cellulase activity K01727 - 4.2.2.1 0.00000000000000009286 93.0
PYH2_k127_4300157_2 domain protein K13735 - - 0.000000000139 75.0
PYH2_k127_4300157_3 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0002365 55.0
PYH2_k127_4305547_0 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 406.0
PYH2_k127_4305547_1 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000006946 232.0
PYH2_k127_4305547_3 Bacterial Ig-like domain 2 - - - 0.0000000000001466 80.0
PYH2_k127_4305547_4 Type II secretion system protein C K02452 - - 0.0005426 49.0
PYH2_k127_4307850_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 376.0
PYH2_k127_4307850_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 366.0
PYH2_k127_4307850_2 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 327.0
PYH2_k127_4307850_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 315.0
PYH2_k127_4307850_4 cytochrome c5 - - - 0.00000000000000000000003384 102.0
PYH2_k127_4307850_5 Uncharacterized integral membrane protein (DUF2301) - - - 0.000000003 65.0
PYH2_k127_4371310_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1035.0
PYH2_k127_4371310_1 Sulfatase - - - 2.491e-235 745.0
PYH2_k127_4371310_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000008724 136.0
PYH2_k127_4371310_11 cheY-homologous receiver domain - - - 0.000000000000000000000000001639 127.0
PYH2_k127_4371310_12 Smr domain - - - 0.000000000000000000000000001689 113.0
PYH2_k127_4371310_13 chemotaxis K03408 - - 0.0000000000000002084 85.0
PYH2_k127_4371310_14 chemotaxis K03408 - - 0.0000000294 63.0
PYH2_k127_4371310_15 COG0835 Chemotaxis signal transduction protein K03408 - - 0.000001477 56.0
PYH2_k127_4371310_2 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 599.0
PYH2_k127_4371310_3 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 565.0
PYH2_k127_4371310_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 382.0
PYH2_k127_4371310_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002384 240.0
PYH2_k127_4371310_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000004485 202.0
PYH2_k127_4371310_7 response regulator K02658 - - 0.00000000000000000000000000000000000000000000000000001067 205.0
PYH2_k127_4371310_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 3.5.1.44 0.000000000000000000000000000000000000000000000000494 181.0
PYH2_k127_4371310_9 Twitching motility two-component system response regulator PilH K02658 - - 0.0000000000000000000000000000000000000000446 154.0
PYH2_k127_4424621_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1025.0
PYH2_k127_4424621_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.158e-266 841.0
PYH2_k127_4424621_2 proteolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 296.0
PYH2_k127_4424621_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004843 256.0
PYH2_k127_4424621_4 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000002294 176.0
PYH2_k127_4424621_5 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000000000000000646 163.0
PYH2_k127_4424621_6 Response regulator receiver domain - - - 0.00000000000000000000000000000000000001468 149.0
PYH2_k127_4424621_7 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000001004 118.0
PYH2_k127_4424621_8 - - - - 0.0000000000000000000000000001316 123.0
PYH2_k127_4505389_0 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000003317 195.0
PYH2_k127_4505389_1 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000003819 159.0
PYH2_k127_4505389_2 catalase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000001384 62.0
PYH2_k127_4505389_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000639 57.0
PYH2_k127_4595015_0 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001321 282.0
PYH2_k127_4595015_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004904 262.0
PYH2_k127_4595015_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000009049 175.0
PYH2_k127_4613312_0 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 318.0
PYH2_k127_4613312_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000004473 163.0
PYH2_k127_4613312_2 Pilus assembly protein K02662 - - 0.000000000000000001288 97.0
PYH2_k127_4613312_3 Pilus assembly protein, PilO K02664 - - 0.0000000004468 68.0
PYH2_k127_4613312_4 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.000000001533 68.0
PYH2_k127_4613312_5 - - - - 0.0004221 50.0
PYH2_k127_4689609_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 426.0
PYH2_k127_4689609_1 Bacteriophage head to tail connecting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000957 260.0
PYH2_k127_4689609_2 - - - - 0.000002712 57.0
PYH2_k127_4689609_3 - - - - 0.000002754 60.0
PYH2_k127_4694842_0 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
PYH2_k127_4694842_1 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000000005177 215.0
PYH2_k127_4694842_2 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000005596 204.0
PYH2_k127_4694842_3 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000006709 85.0
PYH2_k127_4694842_4 cheY-homologous receiver domain - - - 0.000000008146 65.0
PYH2_k127_4694842_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000008603 63.0
PYH2_k127_4697327_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 566.0
PYH2_k127_4697327_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000007682 199.0
PYH2_k127_4701311_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 469.0
PYH2_k127_4701311_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 377.0
PYH2_k127_4701311_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003628 244.0
PYH2_k127_4701311_3 Peptidase S24-like K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000001233 202.0
PYH2_k127_4701311_4 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000008496 194.0
PYH2_k127_4701311_5 Hsp20/alpha crystallin family - - - 0.000000000000003027 81.0
PYH2_k127_4711505_0 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
PYH2_k127_4711505_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000007116 186.0
PYH2_k127_4711505_2 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000001375 160.0
PYH2_k127_4711505_3 isopentenyl-diphosphate delta-isomerase activity - - - 0.00000000000000000000000000001159 130.0
PYH2_k127_4711505_4 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000003671 127.0
PYH2_k127_4711505_5 Thioredoxin domain - - - 0.0000000000000001161 84.0
PYH2_k127_4711505_6 Iron-sulphur cluster biosynthesis K13628 - - 0.00007796 47.0
PYH2_k127_4727738_0 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000001542 191.0
PYH2_k127_4727738_1 NmrA-like family - - - 0.00000000000000000000000000003788 125.0
PYH2_k127_4727738_2 - - - - 0.000000000000000000000000001076 129.0
PYH2_k127_4729123_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 440.0
PYH2_k127_4729123_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000238 274.0
PYH2_k127_4729123_2 Bacterial regulatory proteins, crp family K01420 - - 0.00000000000000000000000000000000000000000000106 173.0
PYH2_k127_4729123_3 FecR protein - - - 0.0002769 49.0
PYH2_k127_4734166_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.683e-274 854.0
PYH2_k127_4734166_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 611.0
PYH2_k127_4734166_10 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 245.0
PYH2_k127_4734166_11 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000002067 220.0
PYH2_k127_4734166_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000001555 217.0
PYH2_k127_4734166_13 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001367 218.0
PYH2_k127_4734166_14 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000001481 207.0
PYH2_k127_4734166_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000001103 197.0
PYH2_k127_4734166_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000002377 187.0
PYH2_k127_4734166_17 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000000118 161.0
PYH2_k127_4734166_18 Pfam Response regulator receiver - - - 0.000000000000000000000000000003651 124.0
PYH2_k127_4734166_19 Roadblock/LC7 domain - - - 0.000000000000000000000001935 111.0
PYH2_k127_4734166_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 584.0
PYH2_k127_4734166_20 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000003158 100.0
PYH2_k127_4734166_21 PAS fold - - - 0.0000000000000000003155 102.0
PYH2_k127_4734166_22 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.0000000000000003817 92.0
PYH2_k127_4734166_23 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000004359 65.0
PYH2_k127_4734166_24 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000001513 61.0
PYH2_k127_4734166_3 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 550.0
PYH2_k127_4734166_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 398.0
PYH2_k127_4734166_5 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 370.0
PYH2_k127_4734166_6 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 364.0
PYH2_k127_4734166_7 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 308.0
PYH2_k127_4734166_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005051 271.0
PYH2_k127_4734166_9 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008321 256.0
PYH2_k127_4740186_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 336.0
PYH2_k127_4740186_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 311.0
PYH2_k127_4740186_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 289.0
PYH2_k127_4740186_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000419 49.0
PYH2_k127_4741283_0 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.0000000000000000000000000000004104 138.0
PYH2_k127_4741283_1 translation initiation factor activity K03646 - - 0.0001383 51.0
PYH2_k127_4744212_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.231e-233 742.0
PYH2_k127_4744212_1 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000494 235.0
PYH2_k127_4744212_2 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000004265 231.0
PYH2_k127_4744212_3 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000002157 153.0
PYH2_k127_4744212_4 STAS domain - - - 0.00000000001059 70.0
PYH2_k127_4764201_0 PFAM Transketolase K00615 - 2.2.1.1 1.555e-240 757.0
PYH2_k127_4764201_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 545.0
PYH2_k127_4764201_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 328.0
PYH2_k127_4764201_3 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 295.0
PYH2_k127_4764201_4 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
PYH2_k127_4764201_5 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001464 252.0
PYH2_k127_4764201_6 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000002584 228.0
PYH2_k127_4764201_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000002268 202.0
PYH2_k127_4764201_8 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000008 204.0
PYH2_k127_4769357_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 405.0
PYH2_k127_4769357_1 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002048 276.0
PYH2_k127_4769357_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001855 265.0
PYH2_k127_4769357_3 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000007152 246.0
PYH2_k127_4769357_4 PFAM UspA domain protein - - - 0.00000000000000000002852 96.0
PYH2_k127_4782776_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 373.0
PYH2_k127_4782776_1 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 349.0
PYH2_k127_4782776_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
PYH2_k127_4782776_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000974 184.0
PYH2_k127_4782776_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000003291 106.0
PYH2_k127_4782776_5 cell envelope organization K05807,K08309 - - 0.000000000001342 78.0
PYH2_k127_4782776_6 protein related to C-terminal domain of eukaryotic chaperone SACSIN - - - 0.0002535 50.0
PYH2_k127_4804777_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000003316 215.0
PYH2_k127_4804777_1 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000003428 168.0
PYH2_k127_4804777_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000007082 126.0
PYH2_k127_4804777_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001197 119.0
PYH2_k127_4804777_4 Sigma-70 region 2 K03088 - - 0.000000000000000001048 89.0
PYH2_k127_4804777_5 Protein of unknown function (DUF507) - - - 0.000000000004491 70.0
PYH2_k127_4804777_6 Predicted membrane protein (DUF2232) - - - 0.00000000009181 73.0
PYH2_k127_4804777_7 Protein of unknown function (DUF507) - - - 0.0000000004959 65.0
PYH2_k127_4807764_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 443.0
PYH2_k127_4807764_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000002787 222.0
PYH2_k127_4807764_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000009675 115.0
PYH2_k127_4815866_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.647e-254 792.0
PYH2_k127_4815866_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 546.0
PYH2_k127_4815866_2 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 352.0
PYH2_k127_4815866_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000008348 269.0
PYH2_k127_4815866_4 response regulator receiver - - - 0.000000000000000000000000000000000000000000003712 168.0
PYH2_k127_4815866_5 DsrE/DsrF-like family - - - 0.00000006922 59.0
PYH2_k127_4818275_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 437.0
PYH2_k127_4818275_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.000000000000000000000000000000000000000000000002433 179.0
PYH2_k127_4818275_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000005482 131.0
PYH2_k127_4818275_4 Recombinase zinc beta ribbon domain - - - 0.0004181 48.0
PYH2_k127_4825360_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 588.0
PYH2_k127_4825360_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 406.0
PYH2_k127_4825360_2 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000008459 269.0
PYH2_k127_4825360_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000002468 121.0
PYH2_k127_4825360_4 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000007761 78.0
PYH2_k127_4830959_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 432.0
PYH2_k127_4830959_1 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 407.0
PYH2_k127_4830959_2 AIR synthase related protein, N-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000005743 216.0
PYH2_k127_4866981_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 532.0
PYH2_k127_4866981_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000001137 224.0
PYH2_k127_4866981_2 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000008355 133.0
PYH2_k127_4866981_3 - - - - 0.00000000003117 66.0
PYH2_k127_4895700_0 PFAM MscS Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 322.0
PYH2_k127_4895700_1 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000002448 131.0
PYH2_k127_4895700_2 long-chain fatty acid transporting porin activity - - - 0.000000000000001018 87.0
PYH2_k127_4895700_3 response regulator - - - 0.000000000723 69.0
PYH2_k127_4913901_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 2.641e-216 689.0
PYH2_k127_4913901_1 L,D-transpeptidase catalytic domain - - - 0.00000000004302 63.0
PYH2_k127_491887_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1466.0
PYH2_k127_491887_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 372.0
PYH2_k127_491887_2 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000004487 66.0
PYH2_k127_4921644_0 Cache domain - - - 1.213e-251 789.0
PYH2_k127_4921644_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 363.0
PYH2_k127_4921644_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 340.0
PYH2_k127_4921644_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
PYH2_k127_4921644_4 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001386 270.0
PYH2_k127_4921644_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000004546 195.0
PYH2_k127_4921644_6 PFAM PASTA domain - - - 0.00000000000000001356 92.0
PYH2_k127_4921644_7 peptidyl-tyrosine sulfation - - - 0.000000000001597 68.0
PYH2_k127_4970399_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 567.0
PYH2_k127_4970399_1 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 390.0
PYH2_k127_4970399_2 - - - - 0.0000006769 56.0
PYH2_k127_4973736_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000005307 241.0
PYH2_k127_4973736_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000003834 192.0
PYH2_k127_4973736_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000001201 151.0
PYH2_k127_4973736_3 TIGRFAM transcriptional regulator, AbrB family - - - 0.0000000000000000136 84.0
PYH2_k127_4973736_4 Rubrerythrin - - - 0.0000000001388 64.0
PYH2_k127_4976469_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 314.0
PYH2_k127_4976469_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
PYH2_k127_4976469_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001407 255.0
PYH2_k127_4976469_3 Could be involved in septation K06412 - - 0.000000000000000000000000000000001494 132.0
PYH2_k127_4976469_4 Regulatory protein, FmdB family - - - 0.00000000000000001008 88.0
PYH2_k127_4976469_5 PFAM Rhodanese domain protein - - - 0.00000002205 63.0
PYH2_k127_4982223_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 297.0
PYH2_k127_4982223_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000003638 234.0
PYH2_k127_4982223_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000001023 232.0
PYH2_k127_4982223_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000003109 166.0
PYH2_k127_4982223_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000001488 157.0
PYH2_k127_5022708_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 426.0
PYH2_k127_5022708_1 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 313.0
PYH2_k127_5022708_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000006927 114.0
PYH2_k127_5038670_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 409.0
PYH2_k127_5038670_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
PYH2_k127_5108506_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.87e-202 640.0
PYH2_k127_5108506_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000005959 131.0
PYH2_k127_5108506_2 - - - - 0.0000000000000000000000006362 105.0
PYH2_k127_5108506_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00003188 47.0
PYH2_k127_5128510_0 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000001054 229.0
PYH2_k127_5128510_1 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
PYH2_k127_51655_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.081e-314 975.0
PYH2_k127_51655_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 585.0
PYH2_k127_5178671_0 General secretory system II, protein E domain protein K02454 - - 3.84e-221 704.0
PYH2_k127_5178671_1 Transporter associated domain K03699 - - 0.000000000000000000000004376 110.0
PYH2_k127_5192231_0 AMP-binding enzyme C-terminal domain K00666 - - 2.771e-227 711.0
PYH2_k127_5192231_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000002969 189.0
PYH2_k127_5192231_2 peroxiredoxin activity K03564 - 1.11.1.15 0.0003761 47.0
PYH2_k127_53014_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.262e-212 669.0
PYH2_k127_53014_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 458.0
PYH2_k127_53014_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 338.0
PYH2_k127_53014_3 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 291.0
PYH2_k127_53014_4 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000001777 134.0
PYH2_k127_53014_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000001639 100.0
PYH2_k127_53014_6 alkyl hydroperoxide reductase activity - - - 0.000000000000002953 85.0
PYH2_k127_53014_7 Cytochrome c7 and related cytochrome c - - - 0.00000001359 60.0
PYH2_k127_5310408_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 4067.0
PYH2_k127_5310408_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 3.474e-220 694.0
PYH2_k127_5310408_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 420.0
PYH2_k127_5310408_3 Predicted membrane protein (DUF2127) - - - 0.0000000000000000000000000000000000000000000003347 173.0
PYH2_k127_5310408_4 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000005425 129.0
PYH2_k127_5310408_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000001988 106.0
PYH2_k127_5310408_6 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.0000000000000000000000126 102.0
PYH2_k127_5310408_7 - - - - 0.00000000000000001184 87.0
PYH2_k127_5310408_8 Protein of unknown function (DUF1003) - - - 0.00000002794 56.0
PYH2_k127_5310408_9 Protein of unknown function (DUF1003) - - - 0.000267 45.0
PYH2_k127_5311596_0 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000003515 195.0
PYH2_k127_5311596_1 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000212 131.0
PYH2_k127_53199_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 544.0
PYH2_k127_5327814_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 424.0
PYH2_k127_5327814_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000785 246.0
PYH2_k127_5327814_2 SRPBCC domain-containing protein - - - 0.00002792 49.0
PYH2_k127_5375823_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
PYH2_k127_5375823_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 376.0
PYH2_k127_5375823_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 309.0
PYH2_k127_5375823_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000395 263.0
PYH2_k127_5375823_4 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001933 244.0
PYH2_k127_5375823_5 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000009216 200.0
PYH2_k127_5375823_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000249 164.0
PYH2_k127_5375823_7 Domain of unknown function (DUF1858) - - - 0.000000000000000003478 86.0
PYH2_k127_5375823_8 - - - - 0.00000000000000003421 87.0
PYH2_k127_5375823_9 - - - - 0.0000008931 52.0
PYH2_k127_543488_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 371.0
PYH2_k127_5453493_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 287.0
PYH2_k127_5453493_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000002309 239.0
PYH2_k127_5455898_0 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 396.0
PYH2_k127_5455898_1 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH2_k127_5455898_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000904 252.0
PYH2_k127_5455898_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000647 189.0
PYH2_k127_5455898_4 - - - - 0.0000000000000000000000008071 110.0
PYH2_k127_5455898_5 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000001409 91.0
PYH2_k127_5530747_0 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 395.0
PYH2_k127_5530747_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000002852 209.0
PYH2_k127_5530747_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.000000000009785 66.0
PYH2_k127_5538171_0 PFAM aminotransferase, class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 515.0
PYH2_k127_5538171_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000003298 209.0
PYH2_k127_5579209_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 5.073e-205 657.0
PYH2_k127_5579209_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 376.0
PYH2_k127_5579209_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
PYH2_k127_5579209_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000004192 243.0
PYH2_k127_5579209_4 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000002225 226.0
PYH2_k127_5579209_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000007291 110.0
PYH2_k127_5579209_6 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000001117 92.0
PYH2_k127_5592189_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.721e-228 733.0
PYH2_k127_5592189_1 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 471.0
PYH2_k127_5592189_10 lipoprotein involved in nitrous oxide reduction - - - 0.000000003359 66.0
PYH2_k127_5592189_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 426.0
PYH2_k127_5592189_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 346.0
PYH2_k127_5592189_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000002391 265.0
PYH2_k127_5592189_5 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002899 233.0
PYH2_k127_5592189_6 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000000000002512 189.0
PYH2_k127_5592189_7 - - - - 0.000000000000000000000000000000000000000000000000494 181.0
PYH2_k127_5592189_8 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000002225 158.0
PYH2_k127_5592189_9 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000007323 76.0
PYH2_k127_5619439_0 Hemerythrin HHE cation binding K07322 - - 0.0000000000000000000000000000000000003434 145.0
PYH2_k127_5619439_1 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000003296 133.0
PYH2_k127_5619439_2 - - - - 0.00000000000000000000000000002475 121.0
PYH2_k127_5619439_3 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000000006639 96.0
PYH2_k127_5623434_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 4.33e-231 734.0
PYH2_k127_5623434_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 382.0
PYH2_k127_5623434_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
PYH2_k127_5623434_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000007628 181.0
PYH2_k127_5623434_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000001371 175.0
PYH2_k127_5623434_5 membrane protein (DUF2207) - - - 0.00000000000000001572 98.0
PYH2_k127_5623434_6 - - - - 0.0000000284 64.0
PYH2_k127_5623434_7 - - - - 0.00000002956 61.0
PYH2_k127_5648706_0 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 2.372e-218 706.0
PYH2_k127_5648706_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 460.0
PYH2_k127_5648706_10 nuclease activity - - - 0.0000000002756 63.0
PYH2_k127_5648706_2 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 426.0
PYH2_k127_5648706_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 417.0
PYH2_k127_5648706_4 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000002559 212.0
PYH2_k127_5648706_5 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000004278 206.0
PYH2_k127_5648706_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000009919 178.0
PYH2_k127_5648706_7 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.000000000000000000000000006179 111.0
PYH2_k127_5648706_8 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000001696 107.0
PYH2_k127_5654314_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.647e-202 636.0
PYH2_k127_5654314_1 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 427.0
PYH2_k127_5654314_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009648 265.0
PYH2_k127_5654314_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
PYH2_k127_5677152_0 Alpha/beta hydrolase family K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 409.0
PYH2_k127_5677152_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 324.0
PYH2_k127_5677152_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000003782 175.0
PYH2_k127_568178_0 Capsule polysaccharide biosynthesis protein K07266 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 421.0
PYH2_k127_568178_1 - - - - 0.00000000000000000000000000000000007597 137.0
PYH2_k127_568178_2 InterPro IPR007367 - - - 0.0000000000000000000002443 98.0
PYH2_k127_5688611_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 365.0
PYH2_k127_5688611_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
PYH2_k127_5688611_2 NOG31153 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
PYH2_k127_5688611_4 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.000003296 50.0
PYH2_k127_5704771_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 434.0
PYH2_k127_5704771_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001925 294.0
PYH2_k127_570918_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000003775 126.0
PYH2_k127_570918_1 - - - - 0.00000000000001673 82.0
PYH2_k127_570918_2 - - - - 0.00003834 49.0
PYH2_k127_57316_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 489.0
PYH2_k127_57316_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 458.0
PYH2_k127_57316_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000002871 247.0
PYH2_k127_57316_3 Amidohydrolase family K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000006394 205.0
PYH2_k127_57316_4 Methyltransferase domain - - - 0.00000000000000000000000000000184 132.0
PYH2_k127_5741868_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.363e-282 895.0
PYH2_k127_5741868_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 511.0
PYH2_k127_5741868_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 410.0
PYH2_k127_5741868_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 369.0
PYH2_k127_5741868_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001429 281.0
PYH2_k127_5741868_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000001377 231.0
PYH2_k127_5741868_6 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000001213 123.0
PYH2_k127_5741868_7 OmpA-like transmembrane domain - - - 0.00001286 54.0
PYH2_k127_5744496_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002286 283.0
PYH2_k127_5744496_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
PYH2_k127_5744496_2 Bacterial PH domain - - - 0.00004962 53.0
PYH2_k127_5754229_0 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 510.0
PYH2_k127_5754229_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
PYH2_k127_5754229_2 TRCF K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 377.0
PYH2_k127_5754229_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 292.0
PYH2_k127_5754229_4 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001608 188.0
PYH2_k127_5754229_5 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000001291 145.0
PYH2_k127_5754229_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000003027 136.0
PYH2_k127_5754229_7 - - - - 0.000000000000000000002895 96.0
PYH2_k127_5754229_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000004401 69.0
PYH2_k127_5755353_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 433.0
PYH2_k127_5755353_1 Electron transport complex K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 335.0
PYH2_k127_5755353_2 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
PYH2_k127_5755353_3 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000002961 165.0
PYH2_k127_5755353_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000001254 160.0
PYH2_k127_575869_0 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003597 262.0
PYH2_k127_575869_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000002187 78.0
PYH2_k127_575869_2 Diguanylate cyclase - - - 0.000000003066 66.0
PYH2_k127_5793566_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.132e-227 711.0
PYH2_k127_5793566_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 294.0
PYH2_k127_5793566_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000002657 179.0
PYH2_k127_5803137_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 1.495e-233 730.0
PYH2_k127_5803137_1 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000349 252.0
PYH2_k127_5803137_2 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000001636 70.0
PYH2_k127_5808569_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 347.0
PYH2_k127_5808569_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000007451 192.0
PYH2_k127_5808569_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000001196 148.0
PYH2_k127_5808569_3 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000003117 109.0
PYH2_k127_5808569_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000009678 97.0
PYH2_k127_5815815_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 1.184e-230 732.0
PYH2_k127_5815815_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 362.0
PYH2_k127_5815815_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000001113 90.0
PYH2_k127_5821961_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.394e-239 756.0
PYH2_k127_5821961_1 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000669 167.0
PYH2_k127_5821961_2 hydrolase, TatD family K03424 - - 0.00000000000000000000000000005071 118.0
PYH2_k127_5824777_0 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 551.0
PYH2_k127_5824777_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 330.0
PYH2_k127_5824777_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
PYH2_k127_5824777_3 - - - - 0.000000000000004139 81.0
PYH2_k127_5833404_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K03776 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0016020,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0050918,GO:0051716,GO:0052128,GO:0052131,GO:0065007,GO:0071944 - 0.000000000000000000000003688 109.0
PYH2_k127_5833404_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000001539 98.0
PYH2_k127_5833404_2 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000955 96.0
PYH2_k127_5833404_3 Protein of unknown function (DUF1232) - - - 0.000000000007872 72.0
PYH2_k127_5836796_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 546.0
PYH2_k127_5836796_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006489 252.0
PYH2_k127_5836796_2 radical SAM domain protein - - - 0.0005274 48.0
PYH2_k127_5857256_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 435.0
PYH2_k127_5857256_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000002163 141.0
PYH2_k127_5857256_2 - - - - 0.0000000000000000000000001656 109.0
PYH2_k127_5857256_3 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000007087 65.0
PYH2_k127_5864337_0 General secretory system II, protein E domain protein K02652 - - 9.614e-219 694.0
PYH2_k127_5864337_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001262 283.0
PYH2_k127_5864337_2 Belongs to the UPF0307 family K09889 - - 0.0000000000001293 75.0
PYH2_k127_5864337_3 TIGRFAM Outer membrane protein K13735,K20276 - - 0.000001116 63.0
PYH2_k127_5864337_4 Histone deacetylase domain - - - 0.0003485 46.0
PYH2_k127_5868245_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 381.0
PYH2_k127_5868245_1 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000006401 243.0
PYH2_k127_5868245_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000002044 222.0
PYH2_k127_5868245_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000002104 199.0
PYH2_k127_5886130_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 522.0
PYH2_k127_5886130_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000006194 161.0
PYH2_k127_5886130_2 Histidine kinase K07778 - 2.7.13.3 0.000003302 53.0
PYH2_k127_5958636_0 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
PYH2_k127_5958636_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000001021 194.0
PYH2_k127_5961546_0 HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000252 239.0
PYH2_k127_5961546_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000003886 199.0
PYH2_k127_5961546_2 PFAM CBS domain - - - 0.000000000000000000000000000001312 128.0
PYH2_k127_5961546_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000004186 90.0
PYH2_k127_5961546_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000002891 75.0
PYH2_k127_5965951_0 ABC transporter C-terminal domain K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 494.0
PYH2_k127_5965951_1 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 418.0
PYH2_k127_5965951_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 400.0
PYH2_k127_5965951_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 348.0
PYH2_k127_5965951_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 339.0
PYH2_k127_5965951_5 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000006367 119.0
PYH2_k127_5974431_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 415.0
PYH2_k127_5974431_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
PYH2_k127_5974431_2 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000006181 151.0
PYH2_k127_5979217_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 409.0
PYH2_k127_5979217_1 Universal stress protein family - - - 0.000002384 55.0
PYH2_k127_5989119_0 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 477.0
PYH2_k127_5989119_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 403.0
PYH2_k127_5989119_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 398.0
PYH2_k127_5989119_3 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006853 288.0
PYH2_k127_5994071_0 PFAM AsmA family protein K07289,K07290 - - 0.0000000000000000000000000000000000000000557 158.0
PYH2_k127_5994071_1 SMART Elongator protein 3 MiaB NifB - - - 0.0004736 42.0
PYH2_k127_5994071_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0009869 44.0
PYH2_k127_6054679_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000007433 241.0
PYH2_k127_6054679_1 double-strand break repair protein AddB K16899 - 3.6.4.12 0.0000000000000000000000005045 121.0
PYH2_k127_6091595_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 499.0
PYH2_k127_6091595_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 417.0
PYH2_k127_6091595_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 367.0
PYH2_k127_6091595_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 323.0
PYH2_k127_6091595_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 301.0
PYH2_k127_6091595_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922,K06281 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0009897,GO:0009986,GO:0016020,GO:0016151,GO:0019897,GO:0019898,GO:0031232,GO:0031236,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0098552,GO:0098567 1.12.5.1,1.12.99.6 0.0000000000000000000000000002502 114.0
PYH2_k127_6091595_6 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000002585 114.0
PYH2_k127_6091595_7 EamA-like transporter family - - - 0.0000005263 61.0
PYH2_k127_609571_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 453.0
PYH2_k127_609571_1 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000007249 121.0
PYH2_k127_6163233_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 491.0
PYH2_k127_6163233_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 308.0
PYH2_k127_6163233_2 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001398 237.0
PYH2_k127_6163233_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000004178 179.0
PYH2_k127_6163233_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000003302 96.0
PYH2_k127_6163233_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000001239 70.0
PYH2_k127_6163233_6 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000002923 72.0
PYH2_k127_620526_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.519e-217 689.0
PYH2_k127_620526_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000002139 134.0
PYH2_k127_6229126_0 Lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 302.0
PYH2_k127_6229126_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000005128 170.0
PYH2_k127_6229126_2 helicase K03722 - 3.6.4.12 0.0000000000000000000006807 98.0
PYH2_k127_6244289_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.146e-204 650.0
PYH2_k127_6244289_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 475.0
PYH2_k127_6244289_10 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000006463 78.0
PYH2_k127_6244289_2 synthase K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 334.0
PYH2_k127_6244289_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 295.0
PYH2_k127_6244289_4 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009767 278.0
PYH2_k127_6244289_5 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
PYH2_k127_6244289_6 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
PYH2_k127_6244289_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001425 227.0
PYH2_k127_6244289_8 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000131 117.0
PYH2_k127_6244289_9 Histidine kinase - - - 0.000000000000000000009888 96.0
PYH2_k127_625843_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000004284 271.0
PYH2_k127_625843_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000008924 272.0
PYH2_k127_625843_2 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000003517 123.0
PYH2_k127_625843_3 PilZ domain - - - 0.0002609 48.0
PYH2_k127_6267038_0 SMART Nucleotide binding protein PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001705 252.0
PYH2_k127_6267038_1 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000001077 207.0
PYH2_k127_6267038_2 L-threonylcarbamoyladenylate synthase K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000005803 181.0
PYH2_k127_6270038_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1081.0
PYH2_k127_6270038_1 Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
PYH2_k127_6270038_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 336.0
PYH2_k127_6270038_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006761 274.0
PYH2_k127_6277534_0 DNA polymerase A domain K02335 - 2.7.7.7 9.513e-303 953.0
PYH2_k127_6277534_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 564.0
PYH2_k127_6277534_10 Fibronectin type III domain - - - 0.0004032 51.0
PYH2_k127_6277534_2 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 290.0
PYH2_k127_6277534_3 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007605 269.0
PYH2_k127_6277534_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000003367 232.0
PYH2_k127_6277534_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000002736 197.0
PYH2_k127_6277534_6 PFAM peptidase M4 thermolysin - - - 0.000000000009119 77.0
PYH2_k127_6277534_7 - - - - 0.0000000006306 71.0
PYH2_k127_6277534_8 PFAM Late competence development protein ComFB K02241 - - 0.00000005592 58.0
PYH2_k127_6277534_9 - - - - 0.0002845 49.0
PYH2_k127_6295314_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 510.0
PYH2_k127_6295314_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 317.0
PYH2_k127_6295314_2 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000002095 184.0
PYH2_k127_6482978_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 321.0
PYH2_k127_6482978_1 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
PYH2_k127_6482978_2 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000001663 203.0
PYH2_k127_6543078_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 478.0
PYH2_k127_6543078_1 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000009896 220.0
PYH2_k127_6543078_2 - - - - 0.000000000000000000000000000000003992 134.0
PYH2_k127_6543078_3 protein ubiquitination K15502,K15503 - - 0.00000001016 66.0
PYH2_k127_6546430_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 383.0
PYH2_k127_6546430_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000002421 180.0
PYH2_k127_6553918_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 9.157e-263 822.0
PYH2_k127_6553918_1 NHL repeat - - - 0.000000000000000000000000000000000000000000003565 178.0
PYH2_k127_6553918_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000001443 168.0
PYH2_k127_6553918_3 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000001031 160.0
PYH2_k127_6553918_4 - - - - 0.000000006912 59.0
PYH2_k127_6555015_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 472.0
PYH2_k127_6555015_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000002366 146.0
PYH2_k127_6555740_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
PYH2_k127_6555740_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 411.0
PYH2_k127_6555740_2 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 367.0
PYH2_k127_6555740_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 325.0
PYH2_k127_6555740_4 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 314.0
PYH2_k127_6555740_5 diguanylate cyclase activity K02000,K04767,K05847,K07168,K09137 - 3.6.3.32 0.000000000000000000000003651 106.0
PYH2_k127_6558345_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
PYH2_k127_6558345_1 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000001105 161.0
PYH2_k127_6558345_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000118 59.0
PYH2_k127_6577385_0 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 316.0
PYH2_k127_6577385_1 CBS domain containing protein K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000001571 270.0
PYH2_k127_6577385_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000009073 194.0
PYH2_k127_6577385_3 Rhs Family K20276 - - 0.00000000000000006226 87.0
PYH2_k127_6581351_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 578.0
PYH2_k127_6581351_1 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.000000000000000000000000000000000000002196 160.0
PYH2_k127_6581351_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000007913 135.0
PYH2_k127_6593243_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 396.0
PYH2_k127_6593243_1 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 342.0
PYH2_k127_6593243_2 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000003803 139.0
PYH2_k127_6593243_3 response regulator K07814 - - 0.000000000004783 75.0
PYH2_k127_6593243_4 Uncharacterized ACR, COG1430 K09005 - - 0.000000001955 70.0
PYH2_k127_6622186_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001609 268.0
PYH2_k127_6622186_1 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000001969 273.0
PYH2_k127_6638375_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 605.0
PYH2_k127_6644214_0 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 461.0
PYH2_k127_6644214_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
PYH2_k127_6644214_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 391.0
PYH2_k127_6644214_3 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 353.0
PYH2_k127_6644214_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004838 275.0
PYH2_k127_6644214_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001995 277.0
PYH2_k127_6644214_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009425 251.0
PYH2_k127_6644214_7 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000005241 197.0
PYH2_k127_6644214_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000001343 173.0
PYH2_k127_6644214_9 Tetratricopeptide repeat K04734,K09553,K16362 GO:0000003,GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006950,GO:0007275,GO:0007568,GO:0008022,GO:0008150,GO:0008340,GO:0009266,GO:0009408,GO:0009628,GO:0010259,GO:0012505,GO:0030234,GO:0030544,GO:0031072,GO:0032501,GO:0032502,GO:0032780,GO:0032991,GO:0042030,GO:0043086,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0048856,GO:0050790,GO:0050896,GO:0051087,GO:0051336,GO:0051346,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772,GO:0101031 - 0.000005768 58.0
PYH2_k127_6652286_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
PYH2_k127_6652286_1 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000002371 200.0
PYH2_k127_6652286_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000002611 162.0
PYH2_k127_6652286_3 - - - - 0.000000000000000000000003115 104.0
PYH2_k127_6657160_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000007714 202.0
PYH2_k127_6657160_1 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000002378 147.0
PYH2_k127_6657160_2 type II secretion system protein G K02456 - - 0.00000000000000000000001749 106.0
PYH2_k127_6657205_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 359.0
PYH2_k127_6657205_1 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000007263 264.0
PYH2_k127_6657205_2 PFAM YaeQ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006665 225.0
PYH2_k127_6663770_0 CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 496.0
PYH2_k127_6677967_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 597.0
PYH2_k127_6684067_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 304.0
PYH2_k127_6684067_1 acid phosphatase activity K03651 - 3.1.4.53 0.00000000000000000000002706 109.0
PYH2_k127_6685402_0 COG0058 Glucan phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 452.0
PYH2_k127_6685402_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 428.0
PYH2_k127_6685402_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 386.0
PYH2_k127_6685402_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000001007 198.0
PYH2_k127_6685402_4 Zincin-like metallopeptidase - - - 0.000000000000000000000000121 110.0
PYH2_k127_6689435_0 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001559 276.0
PYH2_k127_6689435_1 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000004007 220.0
PYH2_k127_6689435_2 Putative methyltransferase - - - 0.000000000000000000000000001702 124.0
PYH2_k127_6692390_0 Bacterial protein of unknown function (DUF853) - - - 7.91e-208 662.0
PYH2_k127_6692390_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 363.0
PYH2_k127_6692390_10 Histidine Phosphotransfer domain - - - 0.00001602 57.0
PYH2_k127_6692390_11 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00002803 55.0
PYH2_k127_6692390_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 332.0
PYH2_k127_6692390_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
PYH2_k127_6692390_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000288 233.0
PYH2_k127_6692390_5 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000003266 206.0
PYH2_k127_6692390_6 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000001171 147.0
PYH2_k127_6692390_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000002499 102.0
PYH2_k127_6692390_8 - - - - 0.00000000000000002345 85.0
PYH2_k127_6692390_9 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000409 78.0
PYH2_k127_6713030_0 helicase superfamily c-terminal domain K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 567.0
PYH2_k127_6713030_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 255.0
PYH2_k127_6713030_2 ATP cone domain K07738 - - 0.00000000000000000000000000000000000000000000000000000000047 206.0
PYH2_k127_6715014_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000004788 100.0
PYH2_k127_6715014_1 Domain of unknown function (DUF4266) - - - 0.0002535 50.0
PYH2_k127_6729595_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001392 254.0
PYH2_k127_6729595_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000002703 132.0
PYH2_k127_6729595_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000001237 87.0
PYH2_k127_6737996_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.188e-276 868.0
PYH2_k127_6737996_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0009616 50.0
PYH2_k127_6744040_0 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 364.0
PYH2_k127_6744040_1 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000001817 181.0
PYH2_k127_6744040_2 general secretion pathway protein - - - 0.000000000000001358 83.0
PYH2_k127_6744040_3 Type IV pilus assembly protein PilM; K02461 - - 0.00000000005968 71.0
PYH2_k127_6744040_4 Type II secretion system (T2SS), protein K K02460 - - 0.000005014 58.0
PYH2_k127_6744040_5 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000209 51.0
PYH2_k127_6744040_6 general secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0001622 52.0
PYH2_k127_6783864_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 490.0
PYH2_k127_6783864_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 282.0
PYH2_k127_6783864_2 Serine Threonine protein kinase K08738 - - 0.000000000005759 78.0
PYH2_k127_6783864_3 Belongs to the HesB IscA family K13628 - - 0.00000000001988 70.0
PYH2_k127_6802819_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 494.0
PYH2_k127_6802819_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 458.0
PYH2_k127_6802819_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 326.0
PYH2_k127_6802819_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
PYH2_k127_6802819_4 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004302 272.0
PYH2_k127_6802819_5 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000005954 202.0
PYH2_k127_6802819_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000006815 188.0
PYH2_k127_6802819_7 Cell surface protein - - - 0.00000000000000000006305 105.0
PYH2_k127_6803899_0 Glycosyl hydrolase family 57 - - - 8.967e-203 654.0
PYH2_k127_6803899_1 COG3524 Capsule polysaccharide export protein K10107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 362.0
PYH2_k127_6803899_2 SMART ATPase, AAA type, core K09689 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 333.0
PYH2_k127_6803899_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 331.0
PYH2_k127_6803899_4 Transport permease protein K09688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001289 258.0
PYH2_k127_6803899_5 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000000000000000000000000002252 176.0
PYH2_k127_6803899_6 HEPN domain - - - 0.00000000000000003792 87.0
PYH2_k127_6803899_7 cell cycle K05589,K12065,K13052 - - 0.000000009582 61.0
PYH2_k127_6829804_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 543.0
PYH2_k127_6829804_1 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000001094 192.0
PYH2_k127_6829804_2 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000114 55.0
PYH2_k127_6836063_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1150.0
PYH2_k127_6836063_1 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 548.0
PYH2_k127_6836063_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 361.0
PYH2_k127_6836063_3 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000003539 194.0
PYH2_k127_6836063_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001183 183.0
PYH2_k127_6836063_5 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000003664 132.0
PYH2_k127_6836063_6 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000003117 66.0
PYH2_k127_6837314_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 450.0
PYH2_k127_6837314_1 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 402.0
PYH2_k127_6837314_2 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 345.0
PYH2_k127_6837314_3 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000005364 112.0
PYH2_k127_6837314_4 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000001429 107.0
PYH2_k127_6837314_5 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000426 100.0
PYH2_k127_6837314_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.0000000000000007364 80.0
PYH2_k127_6890469_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 355.0
PYH2_k127_6890469_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000689 273.0
PYH2_k127_6890469_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003103 259.0
PYH2_k127_6890469_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000002372 254.0
PYH2_k127_6890469_4 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000009774 198.0
PYH2_k127_6890469_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000001007 207.0
PYH2_k127_6890469_6 PFAM Glycosyl transferases group 1 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.0000000000000000325 93.0
PYH2_k127_6899677_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 456.0
PYH2_k127_6899677_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 346.0
PYH2_k127_6899677_2 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 317.0
PYH2_k127_6899677_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000001 234.0
PYH2_k127_6899677_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000005485 191.0
PYH2_k127_6899677_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000002898 161.0
PYH2_k127_6899677_6 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000003978 98.0
PYH2_k127_6899677_7 Protein conserved in bacteria K11719 - - 0.0000000002182 70.0
PYH2_k127_6963509_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 342.0
PYH2_k127_6963509_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
PYH2_k127_6963509_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000002002 160.0
PYH2_k127_6963509_3 TPR repeat - - - 0.000000003589 66.0
PYH2_k127_6963509_4 mRNA catabolic process - - - 0.00009202 45.0
PYH2_k127_6990336_0 GAD domain K01876 - 6.1.1.12 2.044e-225 709.0
PYH2_k127_6990336_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 398.0
PYH2_k127_6990336_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000001233 175.0
PYH2_k127_6990336_3 Belongs to the SfsA family K06206 - - 0.0000000000000001179 81.0
PYH2_k127_6990336_4 Hemerythrin K07216 - - 0.0000000000000003626 84.0
PYH2_k127_7003701_0 acetylesterase activity K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
PYH2_k127_7003701_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000005761 207.0
PYH2_k127_7005626_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 551.0
PYH2_k127_7005626_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 423.0
PYH2_k127_7005626_10 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000001981 205.0
PYH2_k127_7005626_11 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000002863 170.0
PYH2_k127_7005626_12 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000009786 145.0
PYH2_k127_7005626_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000003705 114.0
PYH2_k127_7005626_14 - - - - 0.00000000000000000000000004013 119.0
PYH2_k127_7005626_15 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000002048 78.0
PYH2_k127_7005626_17 peptidyl-tyrosine sulfation - - - 0.00000000000706 73.0
PYH2_k127_7005626_18 Domain of unknown function (DUF3786) - - - 0.0000000004924 68.0
PYH2_k127_7005626_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 376.0
PYH2_k127_7005626_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
PYH2_k127_7005626_4 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 301.0
PYH2_k127_7005626_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 305.0
PYH2_k127_7005626_6 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002772 288.0
PYH2_k127_7005626_7 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
PYH2_k127_7005626_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000003058 258.0
PYH2_k127_7005626_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
PYH2_k127_7013739_0 aconitate hydratase K01681 - 4.2.1.3 3.538e-280 875.0
PYH2_k127_7013739_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 435.0
PYH2_k127_7013739_2 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
PYH2_k127_7013739_3 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000003371 145.0
PYH2_k127_7013739_4 Universal stress protein family - - - 0.00000000000000000000000000000000007857 139.0
PYH2_k127_7013739_5 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000744 127.0
PYH2_k127_7013739_6 NlpC/P60 family K20742 - 3.4.14.13 0.0000000000000000004361 101.0
PYH2_k127_7031005_0 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000002358 145.0
PYH2_k127_7031005_1 Phospholipid methyltransferase - - - 0.000000000000000000001061 104.0
PYH2_k127_7031005_2 serine threonine protein kinase - - - 0.0000000000008185 77.0
PYH2_k127_7054231_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1413.0
PYH2_k127_7054231_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000001725 191.0
PYH2_k127_716046_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 486.0
PYH2_k127_716046_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 443.0
PYH2_k127_716046_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 314.0
PYH2_k127_716046_3 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003333 257.0
PYH2_k127_7193114_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 492.0
PYH2_k127_7219178_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.298e-209 663.0
PYH2_k127_7219178_1 Domains REC, HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000002258 226.0
PYH2_k127_7219178_2 Extracellular solute-binding protein family 3 K07679 - 2.7.13.3 0.000000000000000000000000000000000000003356 168.0
PYH2_k127_7300538_0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 505.0
PYH2_k127_7300538_1 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000103 138.0
PYH2_k127_7300538_2 - - - - 0.00000000000000000000000008522 116.0
PYH2_k127_7300538_3 - - - - 0.000000000007635 68.0
PYH2_k127_7319411_0 Elongation factor G, domain IV K02355 - - 1.528e-228 722.0
PYH2_k127_7319411_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 411.0
PYH2_k127_7319411_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 392.0
PYH2_k127_7319411_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000004574 182.0
PYH2_k127_7388379_0 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000127 200.0
PYH2_k127_7388379_1 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000001083 169.0
PYH2_k127_7388379_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000001682 125.0
PYH2_k127_739699_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.715e-205 649.0
PYH2_k127_739699_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 1.401e-197 633.0
PYH2_k127_739699_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001749 283.0
PYH2_k127_739699_11 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000004838 128.0
PYH2_k127_739699_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 614.0
PYH2_k127_739699_3 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 547.0
PYH2_k127_739699_4 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 531.0
PYH2_k127_739699_5 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 387.0
PYH2_k127_739699_6 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 381.0
PYH2_k127_739699_7 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 378.0
PYH2_k127_739699_8 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 366.0
PYH2_k127_739699_9 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 355.0
PYH2_k127_7440765_0 - - - - 0.00000000000000000000000000000000000000000000000000000003157 205.0
PYH2_k127_7440765_1 YHS domain protein - - - 0.000000000000000000000000000000000000000000000000000003005 196.0
PYH2_k127_7440765_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000001219 188.0
PYH2_k127_7440765_3 protocatechuate 3,4-dioxygenase - - - 0.00000000000000000000000000000000000000000000002233 177.0
PYH2_k127_7484737_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 414.0
PYH2_k127_7484737_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 415.0
PYH2_k127_7484737_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000002992 79.0
PYH2_k127_7484737_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 371.0
PYH2_k127_7484737_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 348.0
PYH2_k127_7484737_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 348.0
PYH2_k127_7484737_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 299.0
PYH2_k127_7484737_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002469 194.0
PYH2_k127_7484737_7 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000276 173.0
PYH2_k127_7484737_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000001114 144.0
PYH2_k127_7484737_9 Yqey-like protein K09117 - - 0.000000000000000000000000000000000001759 144.0
PYH2_k127_7508159_0 NosL - - - 0.0000000000000000000000000000000000000000000007487 171.0
PYH2_k127_7508159_1 NosL - - - 0.0000000000000000000000000000000000000000001356 164.0
PYH2_k127_7508159_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000005371 156.0
PYH2_k127_7508159_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000006627 71.0
PYH2_k127_7520404_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 326.0
PYH2_k127_7520404_1 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.00000000000000000000000000000000000000000000000007637 183.0
PYH2_k127_7520404_2 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000006159 78.0
PYH2_k127_7523600_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.05e-244 767.0
PYH2_k127_7523600_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 444.0
PYH2_k127_7523600_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000007383 245.0
PYH2_k127_7523600_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000002724 171.0
PYH2_k127_7539614_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 574.0
PYH2_k127_7539614_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000009743 179.0
PYH2_k127_7541925_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000601 271.0
PYH2_k127_7541925_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.000000000007344 71.0
PYH2_k127_7541925_2 Sporulation related domain - - - 0.00000000003638 74.0
PYH2_k127_7550999_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001783 271.0
PYH2_k127_7550999_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009502 266.0
PYH2_k127_7564531_0 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 441.0
PYH2_k127_7564531_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 377.0
PYH2_k127_7564531_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 349.0
PYH2_k127_7564531_3 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 330.0
PYH2_k127_7564531_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007071 274.0
PYH2_k127_7564531_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000001221 97.0
PYH2_k127_7564531_6 Helix-turn-helix domain - - - 0.0000000000000001344 91.0
PYH2_k127_7564531_7 peptidyl-tyrosine sulfation - - - 0.0000000000001012 82.0
PYH2_k127_7564531_8 Annexin repeats K17095 - - 0.000275 53.0
PYH2_k127_7569959_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 553.0
PYH2_k127_7569959_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 323.0
PYH2_k127_7569959_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000001675 203.0
PYH2_k127_7569959_3 ResB family K07399 - - 0.0000000000000000000000000005284 119.0
PYH2_k127_7569959_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000009032 90.0
PYH2_k127_7571536_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 544.0
PYH2_k127_7571536_1 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 485.0
PYH2_k127_7571536_10 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000001233 138.0
PYH2_k127_7571536_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 465.0
PYH2_k127_7571536_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 424.0
PYH2_k127_7571536_4 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 330.0
PYH2_k127_7571536_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
PYH2_k127_7571536_6 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000102 261.0
PYH2_k127_7571536_7 Protein of unknown function (DUF2878) - - - 0.00000000000000000000000000000000000000000000004778 174.0
PYH2_k127_7571536_8 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000004996 165.0
PYH2_k127_7571536_9 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000000000007366 150.0
PYH2_k127_7587728_0 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 401.0
PYH2_k127_7587728_1 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000006742 245.0
PYH2_k127_7587728_2 - - - - 0.000000000000000004147 95.0
PYH2_k127_7588291_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1514.0
PYH2_k127_7588291_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 448.0
PYH2_k127_7588291_2 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000003536 193.0
PYH2_k127_7588291_3 His Kinase A (phosphoacceptor) domain K13533 - 2.7.13.3 0.00000000000000000000000000000000000000002309 169.0
PYH2_k127_7588291_4 DSBA oxidoreductase - - - 0.0000000000000000000000000000000006347 133.0
PYH2_k127_7588291_5 PEP-CTERM motif - - - 0.00000000000000004096 95.0
PYH2_k127_7588291_6 Autoinducer binding domain - - - 0.000000000001358 70.0
PYH2_k127_7610358_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008576 261.0
PYH2_k127_7610358_1 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004017 253.0
PYH2_k127_7610358_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000009842 125.0
PYH2_k127_7610358_3 Dolichol kinase - - - 0.00000000000006003 79.0
PYH2_k127_7610358_4 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00005332 52.0
PYH2_k127_7620616_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 450.0
PYH2_k127_7620616_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 232.0
PYH2_k127_7620616_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000036 191.0
PYH2_k127_7620616_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000001472 166.0
PYH2_k127_7635163_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 488.0
PYH2_k127_7635163_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000002123 216.0
PYH2_k127_7635163_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001148 95.0
PYH2_k127_7635163_3 acetoacetate decarboxylase - - - 0.000000000000001816 85.0
PYH2_k127_7647154_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 7.832e-220 692.0
PYH2_k127_7647154_1 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000008925 221.0
PYH2_k127_7647154_2 Tetratricopeptide repeat - - - 0.0000000000000000000000001232 113.0
PYH2_k127_7647154_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.0000000000000000000005613 102.0
PYH2_k127_7647154_4 - - - - 0.000000001551 65.0
PYH2_k127_7647154_5 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000001255 55.0
PYH2_k127_7652208_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 526.0
PYH2_k127_7652208_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001785 250.0
PYH2_k127_7652208_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000004396 214.0
PYH2_k127_7652208_3 histidine kinase A domain protein domain protein - - - 0.000000000000000003213 89.0
PYH2_k127_7653321_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 597.0
PYH2_k127_7653321_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
PYH2_k127_7653321_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003057 198.0
PYH2_k127_7653321_11 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000006359 201.0
PYH2_k127_7653321_12 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003861 191.0
PYH2_k127_7653321_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000035 208.0
PYH2_k127_7653321_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000004565 178.0
PYH2_k127_7653321_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000001678 171.0
PYH2_k127_7653321_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001687 157.0
PYH2_k127_7653321_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000001579 153.0
PYH2_k127_7653321_18 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000004303 140.0
PYH2_k127_7653321_19 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000001264 143.0
PYH2_k127_7653321_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 326.0
PYH2_k127_7653321_20 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001071 136.0
PYH2_k127_7653321_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000578 125.0
PYH2_k127_7653321_22 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000009128 126.0
PYH2_k127_7653321_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000004325 115.0
PYH2_k127_7653321_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001988 103.0
PYH2_k127_7653321_25 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003992 76.0
PYH2_k127_7653321_26 Ribosomal L29 protein K02904 - - 0.000000000000006837 76.0
PYH2_k127_7653321_27 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003364 66.0
PYH2_k127_7653321_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 325.0
PYH2_k127_7653321_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 301.0
PYH2_k127_7653321_5 ribosomal L5P family C-terminus K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 262.0
PYH2_k127_7653321_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000007938 227.0
PYH2_k127_7653321_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002442 218.0
PYH2_k127_7653321_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004984 200.0
PYH2_k127_7653321_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000005053 203.0
PYH2_k127_7661353_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 490.0
PYH2_k127_7661353_1 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 442.0
PYH2_k127_7661353_3 chemotaxis protein K03406 - - 0.0000005986 58.0
PYH2_k127_7661353_4 Protein of unknown function (DUF3185) - - - 0.0001525 47.0
PYH2_k127_766990_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 499.0
PYH2_k127_766990_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000009008 210.0
PYH2_k127_7678828_0 PAS domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 524.0
PYH2_k127_7678828_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000004513 186.0
PYH2_k127_7678828_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000001455 149.0
PYH2_k127_7678828_3 Lysin motif - - - 0.0000000000000000000000000000128 133.0
PYH2_k127_7678828_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000001295 117.0
PYH2_k127_7678828_5 Rhodanese Homology Domain - - - 0.00000000000000001032 88.0
PYH2_k127_7678828_6 PFAM NHL repeat containing protein - - - 0.000000000329 68.0
PYH2_k127_7694995_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 336.0
PYH2_k127_7694995_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 308.0
PYH2_k127_7694995_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 287.0
PYH2_k127_7694995_3 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008688 255.0
PYH2_k127_7694995_4 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000001115 192.0
PYH2_k127_7694995_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.000000000000342 71.0
PYH2_k127_7699557_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 420.0
PYH2_k127_7699557_1 Metal-dependent phosphohydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 303.0
PYH2_k127_7699557_2 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000001759 194.0
PYH2_k127_7699557_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000000000000000000000004014 119.0
PYH2_k127_7699557_4 Roadblock/LC7 domain - - - 0.000000000009902 69.0
PYH2_k127_7719330_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 522.0
PYH2_k127_7719330_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 485.0
PYH2_k127_7719330_2 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 439.0
PYH2_k127_7719330_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000008363 207.0
PYH2_k127_7719330_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000537 203.0
PYH2_k127_7719547_0 Pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 496.0
PYH2_k127_7719547_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 372.0
PYH2_k127_7719547_2 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 308.0
PYH2_k127_7719547_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000001551 210.0
PYH2_k127_7719547_4 protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000002203 196.0
PYH2_k127_7719547_5 Belongs to the Smg family K03747 - - 0.0000148 54.0
PYH2_k127_7723139_0 response regulator K02481,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 518.0
PYH2_k127_7723139_1 - - - - 0.000000000000000000000000002305 122.0
PYH2_k127_7723139_2 Heavy metal transport detoxification protein K07213 - - 0.0000000000006261 70.0
PYH2_k127_7724539_0 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
PYH2_k127_7724539_1 PFAM CBS domain - - - 0.0000000000000000000000000001041 123.0
PYH2_k127_7724539_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000003047 91.0
PYH2_k127_7724539_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000134 44.0
PYH2_k127_7760933_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1253.0
PYH2_k127_7760933_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 367.0
PYH2_k127_7760933_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 357.0
PYH2_k127_7760933_3 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000002361 135.0
PYH2_k127_7760933_4 YtkA-like - - - 0.00000000000000000000000001546 115.0
PYH2_k127_7760933_5 Outer membrane lipoprotein - - - 0.000000000000000000000002216 116.0
PYH2_k127_7780961_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.508e-260 814.0
PYH2_k127_7780961_1 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 336.0
PYH2_k127_7780961_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000003608 209.0
PYH2_k127_7780961_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000003248 157.0
PYH2_k127_7780961_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000002418 73.0
PYH2_k127_7780961_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000838 68.0
PYH2_k127_7790644_0 PFAM Radical SAM - - - 2.764e-195 619.0
PYH2_k127_7790644_1 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001483 284.0
PYH2_k127_7790644_2 carboxymuconolactone decarboxylase - - - 0.00000000000000000000002622 102.0
PYH2_k127_7790644_3 - - - - 0.0000000000000000009142 90.0
PYH2_k127_7790644_4 - - - - 0.00000000000000874 79.0
PYH2_k127_7802461_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000005271 152.0
PYH2_k127_7802461_1 Domain of unknown function (DUF386) - - - 0.000000000000000000000000004879 118.0
PYH2_k127_7802461_2 Cystathionine beta-lyase K01758,K01760 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.4.1.1,4.4.1.8 0.00000000000000001621 84.0
PYH2_k127_7802461_3 Tetratricopeptide repeat - - - 0.00000000000000007799 91.0
PYH2_k127_7821813_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 357.0
PYH2_k127_7821813_1 histidine kinase A domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003871 284.0
PYH2_k127_7821813_2 PFAM response regulator receiver - - - 0.00005738 49.0
PYH2_k127_7838536_0 mannitol 2-dehydrogenase activity K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 556.0
PYH2_k127_7838536_1 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 355.0
PYH2_k127_7838536_2 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
PYH2_k127_7838536_3 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006486 259.0
PYH2_k127_7838536_4 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003773 250.0
PYH2_k127_7838536_5 Ceramidase - - - 0.0000000000000000000000000000000000000000006325 164.0
PYH2_k127_7838536_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000005826 93.0
PYH2_k127_7838536_7 Ceramidase - - - 0.000006251 51.0
PYH2_k127_7855176_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 544.0
PYH2_k127_7855176_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 458.0
PYH2_k127_7855176_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 369.0
PYH2_k127_7855176_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000008608 169.0
PYH2_k127_7862700_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 492.0
PYH2_k127_7862700_1 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 457.0
PYH2_k127_7862700_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
PYH2_k127_7862700_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 302.0
PYH2_k127_7862700_4 Fe-S cluster domain protein - - - 0.0000000000000000000007993 103.0
PYH2_k127_7862700_5 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000000000000002644 90.0
PYH2_k127_7862700_6 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - GO:0008150,GO:0008152,GO:0009058,GO:0042618,GO:0042619,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000004859 68.0
PYH2_k127_7887849_0 phosphate regulon transcriptional regulatory protein PhoB K07657,K07659 - - 0.000000000000000000000000000000000000001976 150.0
PYH2_k127_7887849_1 Nitroreductase - - - 0.000000000000000000000000000000004796 135.0
PYH2_k127_7953527_0 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 381.0
PYH2_k127_7953527_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000009578 162.0
PYH2_k127_7953527_2 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000002293 140.0
PYH2_k127_7953527_3 response regulator - - - 0.00000000002576 74.0
PYH2_k127_7963180_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 380.0
PYH2_k127_7963180_1 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000000888 169.0
PYH2_k127_7963180_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000005905 161.0
PYH2_k127_7963180_3 - - - - 0.0000000008313 66.0
PYH2_k127_7988664_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 415.0
PYH2_k127_7988664_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 299.0
PYH2_k127_7988664_2 cobalamin synthesis protein, P47K - - - 0.0000000000000000000000000000000000000002615 161.0
PYH2_k127_7988664_3 Tetratricopeptide repeat - - - 0.000000000000000000000003345 106.0
PYH2_k127_7988664_4 cheY-homologous receiver domain - - - 0.0003415 49.0
PYH2_k127_7992938_0 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000005431 182.0
PYH2_k127_7992938_1 PTS system mannose fructose sorbose family IID component K02795,K02796 - - 0.0000000000000000000000000000000000001866 151.0
PYH2_k127_7992938_2 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000000001247 124.0
PYH2_k127_7992938_3 PTS system sorbose subfamily IIB component K02769,K02793,K02794 - 2.7.1.191,2.7.1.202 0.0000000000000000000000000008142 118.0
PYH2_k127_7992938_4 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000003194 89.0
PYH2_k127_7992938_5 PTS system sorbose-specific iic component K02795 - - 0.000000000000000001756 95.0
PYH2_k127_8010810_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 542.0
PYH2_k127_8010810_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 505.0
PYH2_k127_8010810_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 455.0
PYH2_k127_8010810_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 419.0
PYH2_k127_8010810_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 396.0
PYH2_k127_8010810_5 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 333.0
PYH2_k127_8010810_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000003729 224.0
PYH2_k127_8010810_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000001474 214.0
PYH2_k127_8010810_8 Binds the 23S rRNA K02909 - - 0.000000000000000000000001819 106.0
PYH2_k127_8032203_0 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000008703 135.0
PYH2_k127_8032203_1 phosphoribosylformylglycinamidine synthase K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0007275,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0030554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048229,GO:0048856,GO:0055046,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.3.5.3 0.000000000000000000000000000000008563 139.0
PYH2_k127_8032203_2 Polymer-forming cytoskeletal - - - 0.000000000000000000000000001316 116.0
PYH2_k127_8054890_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 1.638e-207 656.0
PYH2_k127_8054890_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 543.0
PYH2_k127_8054890_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000003107 166.0
PYH2_k127_8054890_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000007632 116.0
PYH2_k127_8054890_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000001296 69.0
PYH2_k127_8064748_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 527.0
PYH2_k127_8064748_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 413.0
PYH2_k127_8064748_2 pfam abc K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 298.0
PYH2_k127_8064748_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000004547 216.0
PYH2_k127_8064748_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00000000000000000000000000000000000000005282 153.0
PYH2_k127_807316_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 387.0
PYH2_k127_807316_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000001731 102.0
PYH2_k127_8099905_0 purine nucleobase transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 546.0
PYH2_k127_8099905_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 353.0
PYH2_k127_8099905_2 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
PYH2_k127_8099905_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 312.0
PYH2_k127_8099905_4 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
PYH2_k127_8099905_5 GYD domain - - - 0.0000000000000000000000000000000000000008838 149.0
PYH2_k127_8130081_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001642 268.0
PYH2_k127_8130081_1 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000008617 233.0
PYH2_k127_8130081_2 Belongs to the DsbB family K03611 - - 0.0000000000000000000000000000000000000000000007399 169.0
PYH2_k127_8141095_0 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 347.0
PYH2_k127_8141095_1 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
PYH2_k127_8141095_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000007201 79.0
PYH2_k127_8141095_3 POTRA domain, FtsQ-type K03589 - - 0.00000002947 64.0
PYH2_k127_8154015_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002595 274.0
PYH2_k127_8154015_1 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001007 273.0
PYH2_k127_8154015_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001209 224.0
PYH2_k127_8154015_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000006223 89.0
PYH2_k127_8154015_4 Protein of unknown function (DUF402) - - - 0.00000000000003183 79.0
PYH2_k127_8184232_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 310.0
PYH2_k127_8184232_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000001171 264.0
PYH2_k127_8195205_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001036 277.0
PYH2_k127_8195205_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000001125 177.0
PYH2_k127_8195205_2 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000003132 119.0
PYH2_k127_8195205_3 Histidine kinase - - - 0.000008486 56.0
PYH2_k127_8240652_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 3.325e-195 621.0
PYH2_k127_8240652_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000009957 170.0
PYH2_k127_8240652_2 Transcriptional regulator - - - 0.000000000000000009281 91.0
PYH2_k127_8266950_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 524.0
PYH2_k127_8266950_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 332.0
PYH2_k127_8266950_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 310.0
PYH2_k127_8266950_3 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009813 240.0
PYH2_k127_8272188_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.102e-241 756.0
PYH2_k127_8272188_1 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000001376 121.0
PYH2_k127_8272188_2 Acetyltransferase (GNAT) domain - - - 0.000000000003495 77.0
PYH2_k127_8278674_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 301.0
PYH2_k127_8278674_1 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 264.0
PYH2_k127_8278674_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000006822 252.0
PYH2_k127_8278674_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001265 241.0
PYH2_k127_8278674_4 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000006225 180.0
PYH2_k127_8278674_5 - - - - 0.0000009881 50.0
PYH2_k127_8353161_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000005438 224.0
PYH2_k127_8353161_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000716 138.0
PYH2_k127_8353161_2 Cell division protein FtsL - - - 0.0002024 51.0
PYH2_k127_8407836_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 2.676e-240 779.0
PYH2_k127_8407836_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001836 286.0
PYH2_k127_8407836_2 response to heat K07090 - - 0.00000000000000000000000000000000000000006967 155.0
PYH2_k127_8407836_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000001102 136.0
PYH2_k127_8407836_4 Thioesterase superfamily - - - 0.0000000000000000000000008488 108.0
PYH2_k127_8412193_0 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 362.0
PYH2_k127_8412193_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004521 276.0
PYH2_k127_8412193_2 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000001939 183.0
PYH2_k127_8412193_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000003277 139.0
PYH2_k127_8412193_5 TonB C terminal K03832 - - 0.00000005286 63.0
PYH2_k127_8412897_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.704e-212 669.0
PYH2_k127_8412897_1 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 584.0
PYH2_k127_8412897_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 576.0
PYH2_k127_8412897_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001384 233.0
PYH2_k127_8412897_4 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000001558 229.0
PYH2_k127_8412897_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000001244 134.0
PYH2_k127_8412897_6 PBS lyase HEAT-like repeat - - - 0.000000000000003688 90.0
PYH2_k127_8420788_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 449.0
PYH2_k127_8420788_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 449.0
PYH2_k127_8420788_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 418.0
PYH2_k127_8420788_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 372.0
PYH2_k127_8420788_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 309.0
PYH2_k127_8420788_5 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000001553 135.0
PYH2_k127_8430222_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000003199 239.0
PYH2_k127_8430222_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000001301 82.0
PYH2_k127_8433985_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 496.0
PYH2_k127_8433985_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 409.0
PYH2_k127_8433985_2 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 360.0
PYH2_k127_8433985_3 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000005277 181.0
PYH2_k127_8433985_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000197 106.0
PYH2_k127_8433985_5 small metal-binding protein - - - 0.0001057 49.0
PYH2_k127_8446231_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.22e-254 791.0
PYH2_k127_8446231_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.414e-212 679.0
PYH2_k127_8446231_10 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 340.0
PYH2_k127_8446231_11 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 309.0
PYH2_k127_8446231_12 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002404 273.0
PYH2_k127_8446231_13 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005727 267.0
PYH2_k127_8446231_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003228 258.0
PYH2_k127_8446231_15 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000008803 246.0
PYH2_k127_8446231_16 Glycosyl transferases group 1 K12993 - - 0.00000000000000000000000000000000000000000000000000000000000000004868 240.0
PYH2_k127_8446231_17 - - - - 0.0000000000000000000000000000000000000000000000000000000008351 215.0
PYH2_k127_8446231_18 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000006101 207.0
PYH2_k127_8446231_19 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000001646 197.0
PYH2_k127_8446231_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 7.292e-204 645.0
PYH2_k127_8446231_20 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000001484 187.0
PYH2_k127_8446231_21 FecR protein - - - 0.0000000000000000000000000000000000000000000002997 176.0
PYH2_k127_8446231_22 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000009904 151.0
PYH2_k127_8446231_23 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000002692 121.0
PYH2_k127_8446231_24 response regulator receiver K02481 - - 0.000000000000000000000005619 106.0
PYH2_k127_8446231_25 Transglutaminase-like superfamily - - - 0.000000000000000000001906 109.0
PYH2_k127_8446231_26 FixH - - - 0.000000000000000003286 90.0
PYH2_k127_8446231_27 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0000000000000001973 80.0
PYH2_k127_8446231_28 FixH - - - 0.000000004266 64.0
PYH2_k127_8446231_29 domain protein K20276 - - 0.000000008733 66.0
PYH2_k127_8446231_3 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 566.0
PYH2_k127_8446231_31 LPP20 lipoprotein - - - 0.0000001163 63.0
PYH2_k127_8446231_32 Domain of unknown function (DUF4388) - - - 0.00001218 54.0
PYH2_k127_8446231_33 Glycosyl transferase family 2 - - - 0.00001773 54.0
PYH2_k127_8446231_34 nuclear chromosome segregation - - - 0.00001895 55.0
PYH2_k127_8446231_4 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 412.0
PYH2_k127_8446231_5 PFAM ABC transporter related K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 418.0
PYH2_k127_8446231_6 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 350.0
PYH2_k127_8446231_7 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 351.0
PYH2_k127_8446231_8 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 341.0
PYH2_k127_8446231_9 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 338.0
PYH2_k127_8460186_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 382.0
PYH2_k127_8460186_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000136 242.0
PYH2_k127_8463652_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 305.0
PYH2_k127_8463652_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 277.0
PYH2_k127_8463652_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
PYH2_k127_8487110_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 426.0
PYH2_k127_8487110_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000001896 171.0
PYH2_k127_8487110_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000002315 165.0
PYH2_k127_8489824_0 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 307.0
PYH2_k127_8489824_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000001173 181.0
PYH2_k127_8489824_2 Protein of unknown function (DUF2845) - - - 0.000000000000000000000000000000000117 139.0
PYH2_k127_8490748_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 395.0
PYH2_k127_8490748_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 368.0
PYH2_k127_8490748_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 336.0
PYH2_k127_8490748_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000035 262.0
PYH2_k127_8490748_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000006758 131.0
PYH2_k127_8490748_5 deoxyhypusine monooxygenase activity - - - 0.0000000000000001971 88.0
PYH2_k127_8490748_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000001124 63.0
PYH2_k127_8490748_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000147 58.0
PYH2_k127_8511722_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004888 246.0
PYH2_k127_8511722_2 Outer membrane protease K08566 - 3.4.23.48 0.00000000007476 74.0
PYH2_k127_8511722_3 - - - - 0.00000001973 62.0
PYH2_k127_8511722_4 - - - - 0.000005222 57.0
PYH2_k127_8517714_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.863e-237 741.0
PYH2_k127_8517714_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 392.0
PYH2_k127_8517714_2 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 323.0
PYH2_k127_8517714_3 Adenylate kinase, active site lid K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
PYH2_k127_8517714_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000003281 195.0
PYH2_k127_8517714_5 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000001757 212.0
PYH2_k127_8517714_6 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000007216 151.0
PYH2_k127_8517714_7 Tetratricopeptide repeats - - - 0.0000000000000000000000007316 115.0
PYH2_k127_8517714_8 cheY-homologous receiver domain K03413 - - 0.00000000000000000000002137 105.0
PYH2_k127_8538745_0 Transketolase, thiamine diphosphate binding domain K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 391.0
PYH2_k127_8538745_1 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 350.0
PYH2_k127_8538745_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001576 280.0
PYH2_k127_8538745_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000001933 87.0
PYH2_k127_8542585_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 340.0
PYH2_k127_8542585_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000001261 210.0
PYH2_k127_8553376_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 411.0
PYH2_k127_8553376_1 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 392.0
PYH2_k127_8553376_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000011 145.0
PYH2_k127_8556576_0 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000001723 149.0
PYH2_k127_8573486_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 548.0
PYH2_k127_8573486_1 Universal stress protein family - - - 0.0000000000000000007235 93.0
PYH2_k127_8573486_2 serine threonine protein kinase - - - 0.000000000000001038 78.0
PYH2_k127_8577451_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 578.0
PYH2_k127_8577451_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 294.0
PYH2_k127_8577451_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 264.0
PYH2_k127_8577451_3 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000008316 226.0
PYH2_k127_8577451_4 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000002379 162.0
PYH2_k127_8613228_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 401.0
PYH2_k127_8613228_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 324.0
PYH2_k127_8613228_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000007124 172.0
PYH2_k127_8613228_3 4Fe-4S dicluster domain - - - 0.00000000000007322 73.0
PYH2_k127_8617907_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001915 282.0
PYH2_k127_8617907_1 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000002315 232.0
PYH2_k127_8617907_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000002007 192.0
PYH2_k127_8617907_3 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000003235 121.0
PYH2_k127_8617907_4 OsmC-like protein K07397 - - 0.00000000000000000000006286 108.0
PYH2_k127_8618917_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 538.0
PYH2_k127_8618917_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001379 177.0
PYH2_k127_8618917_2 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.00000000000000000000000000000003027 133.0
PYH2_k127_8655966_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 428.0
PYH2_k127_8655966_1 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000001909 118.0
PYH2_k127_8655966_2 Papain-like cysteine protease AvrRpt2 - - - 0.000000000000000000000008383 109.0
PYH2_k127_8655966_3 - - - - 0.000000000001521 71.0
PYH2_k127_8655966_5 - - - - 0.0003695 46.0
PYH2_k127_8673159_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 522.0
PYH2_k127_8673159_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000004644 162.0
PYH2_k127_8673159_2 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000006486 98.0
PYH2_k127_8676307_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007673 271.0
PYH2_k127_8676307_1 Sigma-54 interaction domain K15836 - - 0.000128 53.0
PYH2_k127_8717791_0 PFAM Tetratricopeptide repeat - - - 1.678e-196 633.0
PYH2_k127_8717791_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 440.0
PYH2_k127_8717791_2 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 332.0
PYH2_k127_8717791_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002308 185.0
PYH2_k127_8717791_4 integral membrane protein - - - 0.00000000000008357 79.0
PYH2_k127_875394_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 609.0
PYH2_k127_875394_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
PYH2_k127_875394_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006488 279.0
PYH2_k127_875394_3 channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 261.0
PYH2_k127_875394_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000001396 187.0
PYH2_k127_875394_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000003204 187.0
PYH2_k127_875394_6 cellulase activity - - - 0.00003818 53.0
PYH2_k127_8769793_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 424.0
PYH2_k127_8769793_1 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000001388 184.0
PYH2_k127_8769793_2 PFAM cobalbumin biosynthesis K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000005045 181.0
PYH2_k127_8769793_3 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000001417 158.0
PYH2_k127_8769793_4 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.000000000000000000000000000000000000000001866 165.0
PYH2_k127_8769793_5 Thioredoxin-like - - - 0.00000000000000000000000000000000004719 145.0
PYH2_k127_8769793_6 4Fe-4S binding domain - - - 0.000000000001037 70.0
PYH2_k127_8769793_7 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000007597 67.0
PYH2_k127_877993_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 421.0
PYH2_k127_877993_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000009663 109.0
PYH2_k127_8806858_0 ABC transporter K06158 - - 2.622e-227 726.0
PYH2_k127_8806858_1 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 511.0
PYH2_k127_8806858_2 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 273.0
PYH2_k127_8806858_3 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000002073 159.0
PYH2_k127_8806858_4 protein phosphatase 2C domain protein - - - 0.000000009663 65.0
PYH2_k127_8834776_0 Transcriptional regulator K07727 - - 0.0000000000000000000000006103 106.0
PYH2_k127_8834776_1 Protein of unknown function (DUF2975) - - - 0.0000000003113 69.0
PYH2_k127_8835707_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1206.0
PYH2_k127_8835707_1 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 339.0
PYH2_k127_8872767_0 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 449.0
PYH2_k127_8872767_1 - - - - 0.0000006176 57.0
PYH2_k127_890775_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000612 285.0
PYH2_k127_890775_1 PFAM chemotaxis sensory transducer K03406,K05874 - - 0.000000000000000000000000000000000001612 144.0
PYH2_k127_890775_2 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000001123 131.0
PYH2_k127_894560_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 472.0
PYH2_k127_894560_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000513 201.0
PYH2_k127_8986358_0 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 256.0
PYH2_k127_8986358_1 Crp-like helix-turn-helix domain K10914 - - 0.0000000000000000000000000000000000000000003704 166.0
PYH2_k127_8986358_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000003731 164.0
PYH2_k127_8986358_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000002345 120.0
PYH2_k127_8986358_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000005244 99.0
PYH2_k127_9001801_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 434.0
PYH2_k127_9001801_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000001711 134.0
PYH2_k127_9001801_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000001649 121.0
PYH2_k127_9144886_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
PYH2_k127_9144886_1 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000000000000000000001583 201.0
PYH2_k127_9144886_2 Ion channel - - - 0.000000000000000000000000000000209 133.0
PYH2_k127_9144886_4 Outer membrane protein beta-barrel domain - - - 0.00000000000000001406 84.0
PYH2_k127_9153262_0 Tricorn protease PDZ domain K08676 - - 0.0 1025.0
PYH2_k127_9311222_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 5.782e-240 758.0
PYH2_k127_9311222_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000001128 70.0
PYH2_k127_934027_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 503.0
PYH2_k127_934027_1 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 481.0
PYH2_k127_934027_2 ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 306.0
PYH2_k127_934027_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000007444 236.0
PYH2_k127_934027_4 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000001021 122.0
PYH2_k127_934027_5 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000001672 116.0
PYH2_k127_934027_6 electron transfer activity K05337,K17247 - - 0.0000000005569 61.0
PYH2_k127_934027_7 EamA-like transporter family - - - 0.0000000817 54.0
PYH2_k127_940071_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
PYH2_k127_940071_1 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
PYH2_k127_940071_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000001456 222.0
PYH2_k127_940071_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000001471 190.0
PYH2_k127_940071_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000464 136.0
PYH2_k127_940071_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000008377 120.0
PYH2_k127_940071_6 - - - - 0.000003301 55.0
PYH2_k127_944207_0 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 518.0
PYH2_k127_944207_1 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000000003219 169.0
PYH2_k127_944207_2 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit K02469 - 5.99.1.3 0.000000000000000000000000000000000007616 145.0
PYH2_k127_944207_3 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000004418 133.0
PYH2_k127_944207_4 cellulase activity K12287 - - 0.000000000000001371 91.0
PYH2_k127_944207_5 Restriction endonuclease - - - 0.0000007441 61.0
PYH2_k127_951465_0 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 327.0
PYH2_k127_951465_1 Methyltransferase type 11 - - - 0.0000001183 56.0
PYH2_k127_951465_2 CHASE - - - 0.0000004862 60.0
PYH2_k127_963845_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 484.0
PYH2_k127_963845_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000007665 151.0
PYH2_k127_963845_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000005507 141.0
PYH2_k127_963845_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000001457 129.0
PYH2_k127_963845_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000002355 117.0
PYH2_k127_967238_0 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 417.0
PYH2_k127_967238_1 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 256.0
PYH2_k127_967238_2 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000335 261.0
PYH2_k127_967238_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000001061 204.0
PYH2_k127_967238_4 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000001528 99.0