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Overview

ID MAG03176
Name PYH2_bin.16
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class UBA6911
Order UBA6911
Family UBA6911
Genus
Species
Assembly information
Completeness (%) 86.07
Contamination (%) 0.02
GC content (%) 62.0
N50 (bp) 20,252
Genome size (bp) 4,751,271

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3753

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_106151_0 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 413.0
PYH2_k127_106151_1 GHMP kinases C terminal K16190 - 2.7.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
PYH2_k127_106151_10 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000003915 189.0
PYH2_k127_106151_11 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000004733 172.0
PYH2_k127_106151_12 Universal stress protein - - - 0.0000000000000000002569 98.0
PYH2_k127_106151_13 - - - - 0.000000000000000001357 88.0
PYH2_k127_106151_14 Belongs to the glycosyl hydrolase 18 family K01179,K01183 - 3.2.1.14,3.2.1.4 0.000000000000000002811 101.0
PYH2_k127_106151_15 Prolipoprotein diacylglyceryl transferase - - - 0.000002193 56.0
PYH2_k127_106151_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 335.0
PYH2_k127_106151_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 336.0
PYH2_k127_106151_4 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 329.0
PYH2_k127_106151_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 308.0
PYH2_k127_106151_6 PFAM peptidase K06402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 267.0
PYH2_k127_106151_7 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004881 264.0
PYH2_k127_106151_8 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000004324 233.0
PYH2_k127_106151_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000001254 199.0
PYH2_k127_106996_0 beta-galactosidase activity - - - 9.176e-250 782.0
PYH2_k127_106996_1 Integrase - - - 0.00000000000000000000000000000005207 144.0
PYH2_k127_106996_2 transposition K07497 - - 0.000000002291 59.0
PYH2_k127_1075571_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000006367 194.0
PYH2_k127_1075571_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000005553 73.0
PYH2_k127_1075571_2 Integrase catalytic K07497 - - 0.0000000000111 76.0
PYH2_k127_107989_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 475.0
PYH2_k127_107989_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 410.0
PYH2_k127_107989_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 365.0
PYH2_k127_107989_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000002061 243.0
PYH2_k127_107989_4 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000003465 201.0
PYH2_k127_107989_5 hyperosmotic response - - - 0.00000000000000000000000000000000002668 142.0
PYH2_k127_107989_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000001009 126.0
PYH2_k127_107989_7 - - - - 0.0000000000000000001181 96.0
PYH2_k127_107989_8 Pfam:UPF0118 - - - 0.000000000002196 67.0
PYH2_k127_1107807_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 441.0
PYH2_k127_1107807_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 442.0
PYH2_k127_1107807_10 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000007646 100.0
PYH2_k127_1107807_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 425.0
PYH2_k127_1107807_3 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 381.0
PYH2_k127_1107807_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 305.0
PYH2_k127_1107807_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 290.0
PYH2_k127_1107807_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001106 286.0
PYH2_k127_1107807_7 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004138 255.0
PYH2_k127_1107807_8 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000001967 170.0
PYH2_k127_1107807_9 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000000000001268 120.0
PYH2_k127_1108103_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000001321 230.0
PYH2_k127_1108103_1 RNA recognition motif - - - 0.00000000000000000000000000000005746 132.0
PYH2_k127_1108103_2 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001844 88.0
PYH2_k127_1108103_3 Domain of unknown function (DUF362) - - - 0.0004854 50.0
PYH2_k127_1116379_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 4.031e-236 756.0
PYH2_k127_1116379_1 Glutamine amidotransferase domain K00820 - 2.6.1.16 1.378e-208 691.0
PYH2_k127_1116379_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 2.711e-200 629.0
PYH2_k127_1116379_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 2.258e-197 642.0
PYH2_k127_1116379_4 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 374.0
PYH2_k127_1116379_5 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 270.0
PYH2_k127_1116379_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000005555 197.0
PYH2_k127_1116379_7 Domain of unknown function (DUF4143) - - - 0.000000000000006771 77.0
PYH2_k127_1116379_8 TamB, inner membrane protein subunit of TAM complex K07277,K09800 - - 0.000000000006691 65.0
PYH2_k127_1116379_9 - - - - 0.00000000001174 71.0
PYH2_k127_1134608_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1309.0
PYH2_k127_1134608_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000004939 170.0
PYH2_k127_1138403_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000002144 194.0
PYH2_k127_1138403_1 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000001208 162.0
PYH2_k127_1138403_10 - - - - 0.0000005596 56.0
PYH2_k127_1138403_11 purine nucleotide biosynthetic process K02529,K05499 - - 0.00003999 49.0
PYH2_k127_1138403_2 - - - - 0.00000000000000000000000000000000002472 138.0
PYH2_k127_1138403_3 - - - - 0.0000000000000000000000000000000515 130.0
PYH2_k127_1138403_4 PFAM Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000001517 115.0
PYH2_k127_1138403_5 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000002249 112.0
PYH2_k127_1138403_8 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000005849 67.0
PYH2_k127_1138403_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000001305 69.0
PYH2_k127_1154424_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.206e-235 743.0
PYH2_k127_1154424_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.33e-210 663.0
PYH2_k127_1154424_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000007325 246.0
PYH2_k127_1154424_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 237.0
PYH2_k127_1154424_12 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000001043 207.0
PYH2_k127_1154424_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000001447 103.0
PYH2_k127_1154424_14 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000003638 97.0
PYH2_k127_1154424_15 Polymer-forming cytoskeletal - - - 0.0000000000000000001755 93.0
PYH2_k127_1154424_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000003503 91.0
PYH2_k127_1154424_17 Yip1 domain - - - 0.00000000000000000331 94.0
PYH2_k127_1154424_18 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000008231 86.0
PYH2_k127_1154424_19 - - - - 0.000000000000000968 82.0
PYH2_k127_1154424_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 510.0
PYH2_k127_1154424_20 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001576 74.0
PYH2_k127_1154424_21 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000006939 58.0
PYH2_k127_1154424_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 393.0
PYH2_k127_1154424_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 381.0
PYH2_k127_1154424_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 351.0
PYH2_k127_1154424_6 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 320.0
PYH2_k127_1154424_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 308.0
PYH2_k127_1154424_8 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 302.0
PYH2_k127_1154424_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001254 289.0
PYH2_k127_1154535_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 336.0
PYH2_k127_1154535_1 SMART band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
PYH2_k127_1156675_0 PFAM Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 421.0
PYH2_k127_1156675_1 - - - - 0.00000000000000000000000000000000000000000000002174 172.0
PYH2_k127_1156675_2 PFAM IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000001022 128.0
PYH2_k127_1156675_4 transposase activity - - - 0.000009186 53.0
PYH2_k127_1156675_5 Glycosyl transferase 4-like domain - - - 0.0004207 45.0
PYH2_k127_1183493_0 Integrase core domain - - - 0.0000000000000000000000000000000000000001015 156.0
PYH2_k127_1183493_1 Beta-lactamase - - - 0.0000000000000000000000000000000000006924 148.0
PYH2_k127_1183493_2 Phage integrase family - - - 0.000000000000003895 84.0
PYH2_k127_1183493_3 Transcriptional regulatory protein, C terminal - - - 0.00000001374 62.0
PYH2_k127_1186852_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 473.0
PYH2_k127_1186852_1 - - - - 0.00000000000000000000000000000000005323 137.0
PYH2_k127_1186852_2 Transposase - - - 0.000000000000000000000000009571 122.0
PYH2_k127_1190249_0 Alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 417.0
PYH2_k127_1190249_1 Domain of unknown function (DUF4091) - - - 0.000000000000000001106 102.0
PYH2_k127_1190249_2 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.000000000003325 68.0
PYH2_k127_1192168_0 Glycosyl hydrolases family 2, sugar binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 439.0
PYH2_k127_1192168_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003907 235.0
PYH2_k127_1192168_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000001484 134.0
PYH2_k127_1200509_0 Cytochrome c554 and c-prime - - - 0.0 1257.0
PYH2_k127_1200509_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1142.0
PYH2_k127_1200509_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 360.0
PYH2_k127_1200509_11 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 354.0
PYH2_k127_1200509_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 334.0
PYH2_k127_1200509_13 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 321.0
PYH2_k127_1200509_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 342.0
PYH2_k127_1200509_15 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 328.0
PYH2_k127_1200509_16 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000261 291.0
PYH2_k127_1200509_17 PFAM response regulator receiver K07659,K11329 - - 0.000000000000000000000000000000000000000000000000000000000000000002094 235.0
PYH2_k127_1200509_18 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000002971 231.0
PYH2_k127_1200509_19 IMP dehydrogenase activity K03281 - - 0.000000000000000000000000000000000000000000000005048 188.0
PYH2_k127_1200509_2 ASPIC and UnbV - - - 1.172e-287 891.0
PYH2_k127_1200509_20 electron transport chain - - - 0.00000000000000000000000000000000000000007193 161.0
PYH2_k127_1200509_21 PhoQ Sensor - - - 0.00000000000000000000000000000000000001909 162.0
PYH2_k127_1200509_22 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.0000000000000000000000000000004665 136.0
PYH2_k127_1200509_23 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000002674 108.0
PYH2_k127_1200509_24 Alkyl hydroperoxide reductase and or thiol-specific antioxidant family (AhpC TSA) protein - - - 0.0000000000000008442 86.0
PYH2_k127_1200509_25 Regulatory protein, FmdB family - - - 0.000000000002695 69.0
PYH2_k127_1200509_26 NMT1-like family K02051 - - 0.000000000301 62.0
PYH2_k127_1200509_3 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 490.0
PYH2_k127_1200509_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 451.0
PYH2_k127_1200509_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 436.0
PYH2_k127_1200509_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 437.0
PYH2_k127_1200509_7 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 395.0
PYH2_k127_1200509_8 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 385.0
PYH2_k127_1200509_9 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 373.0
PYH2_k127_1281142_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 2.198e-228 726.0
PYH2_k127_1281142_1 Flavodoxin-like fold K11748 - - 0.0000000000000000000000000000000000000000000000000000352 191.0
PYH2_k127_1284990_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 429.0
PYH2_k127_1284990_1 Cytochrome c - - - 0.00000000000000000000000004981 113.0
PYH2_k127_1284990_2 COG0346 Lactoylglutathione lyase and related lyases K05606,K07588 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.0000005599 60.0
PYH2_k127_1284990_3 - - - - 0.0001485 45.0
PYH2_k127_1319083_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1523.0
PYH2_k127_1319083_1 Domain of unknown function (DUF362) - - - 1.275e-210 664.0
PYH2_k127_1319083_10 - - - - 0.000000000000000000003122 96.0
PYH2_k127_1319083_11 Transcriptional regulator, DeoR family K21601 - - 0.0006269 47.0
PYH2_k127_1319083_2 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 574.0
PYH2_k127_1319083_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 531.0
PYH2_k127_1319083_4 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 412.0
PYH2_k127_1319083_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 377.0
PYH2_k127_1319083_6 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 348.0
PYH2_k127_1319083_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001245 273.0
PYH2_k127_1319083_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000009942 136.0
PYH2_k127_1358970_0 Fibronectin type III-like domain K05349 - 3.2.1.21 8.469e-237 758.0
PYH2_k127_1358970_1 xyloglucan:xyloglucosyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 501.0
PYH2_k127_1358970_2 BNR repeat-like domain - - - 0.00000009611 60.0
PYH2_k127_1382472_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 405.0
PYH2_k127_1382472_1 PFAM Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
PYH2_k127_1382472_2 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 307.0
PYH2_k127_1382472_3 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000000000001965 176.0
PYH2_k127_1382472_4 DEAD DEAH box helicase domain protein K06877 - - 0.0000000000000000000000000000000000001269 148.0
PYH2_k127_1382472_5 AAA domain - - - 0.000000000000000000000000000002532 140.0
PYH2_k127_1382472_6 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000001776 125.0
PYH2_k127_1382472_7 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000009637 125.0
PYH2_k127_1382472_8 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000001301 51.0
PYH2_k127_1406967_0 Radical SAM domain protein K15045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 458.0
PYH2_k127_1406967_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 441.0
PYH2_k127_1406967_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 364.0
PYH2_k127_1406967_3 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 341.0
PYH2_k127_1406967_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000008122 252.0
PYH2_k127_1406967_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000003375 137.0
PYH2_k127_1406967_6 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000001828 63.0
PYH2_k127_1418136_0 BEST Arabidopsis thaliana protein match is Plant protein of - - - 0.000000000000000000000000000000002455 149.0
PYH2_k127_1418136_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01637 - 4.1.3.1 0.00000000000000000000000000925 128.0
PYH2_k127_141874_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 9.974e-240 749.0
PYH2_k127_141874_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 6.26e-204 663.0
PYH2_k127_141874_10 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 360.0
PYH2_k127_141874_11 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 322.0
PYH2_k127_141874_12 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
PYH2_k127_141874_13 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002211 280.0
PYH2_k127_141874_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000005121 245.0
PYH2_k127_141874_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000004186 261.0
PYH2_k127_141874_16 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000009626 235.0
PYH2_k127_141874_17 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000001249 201.0
PYH2_k127_141874_18 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000002739 183.0
PYH2_k127_141874_19 - - - - 0.0000000000000000000000000000000000000000005866 175.0
PYH2_k127_141874_2 NAD synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 572.0
PYH2_k127_141874_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000704 160.0
PYH2_k127_141874_21 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000001008 153.0
PYH2_k127_141874_22 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000003463 137.0
PYH2_k127_141874_23 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000005948 123.0
PYH2_k127_141874_24 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000003538 119.0
PYH2_k127_141874_25 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000002755 115.0
PYH2_k127_141874_26 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001883 104.0
PYH2_k127_141874_27 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000006818 106.0
PYH2_k127_141874_28 PFAM membrane-flanked domain - - - 0.000000000000000005439 92.0
PYH2_k127_141874_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001522 72.0
PYH2_k127_141874_3 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 580.0
PYH2_k127_141874_30 - - - - 0.000000000000282 76.0
PYH2_k127_141874_31 - - - - 0.000000000004497 78.0
PYH2_k127_141874_4 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 556.0
PYH2_k127_141874_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 492.0
PYH2_k127_141874_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 475.0
PYH2_k127_141874_7 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 448.0
PYH2_k127_141874_8 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 406.0
PYH2_k127_141874_9 PFAM Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 406.0
PYH2_k127_1427742_0 cell wall glycoprotein biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 614.0
PYH2_k127_1427742_1 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 295.0
PYH2_k127_1427742_2 PFAM Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005614 279.0
PYH2_k127_1427742_3 - - - - 0.00002308 58.0
PYH2_k127_1427742_4 HEAT repeats - - - 0.00002308 58.0
PYH2_k127_1477696_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001113 226.0
PYH2_k127_1478666_0 AcrB/AcrD/AcrF family - - - 9.42e-321 1013.0
PYH2_k127_1478666_1 Zinc carboxypeptidase K14054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 542.0
PYH2_k127_1478666_2 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 517.0
PYH2_k127_1478666_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000002996 233.0
PYH2_k127_1478666_4 Integrase catalytic - - - 0.00000001468 60.0
PYH2_k127_1536882_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000005119 203.0
PYH2_k127_1536882_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000005939 171.0
PYH2_k127_1536882_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000005592 151.0
PYH2_k127_1536882_3 translation elongation factor activity K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000001889 81.0
PYH2_k127_1536882_4 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000006116 91.0
PYH2_k127_1536882_5 - - - - 0.000001347 53.0
PYH2_k127_1585537_0 Tricorn protease PDZ domain K08676 - - 0.0 1279.0
PYH2_k127_1585537_1 PFAM Uncharacterised BCR, COG1649 - - - 0.0 1015.0
PYH2_k127_1585537_10 unsaturated chondroitin disaccharide hydrolase activity - - - 0.000000000000000000000000000000000000000000000592 175.0
PYH2_k127_1585537_11 Aldo/keto reductase family - - - 0.00000000000000000000649 94.0
PYH2_k127_1585537_12 PFAM DnaJ homologue, subfamily C, member 28, conserved domain - - - 0.0000000000000001468 83.0
PYH2_k127_1585537_13 Histidine kinase-like ATPase domain - - - 0.000000000000001192 84.0
PYH2_k127_1585537_14 STAS domain - - - 0.0000000001567 65.0
PYH2_k127_1585537_15 Domain of Unknown Function (DUF1080) - - - 0.000000004699 59.0
PYH2_k127_1585537_16 Psort location CytoplasmicMembrane, score - - - 0.000009792 57.0
PYH2_k127_1585537_2 PFAM oxidoreductase domain protein - - - 1.702e-228 719.0
PYH2_k127_1585537_3 Tricorn protease homolog - - - 9.455e-228 711.0
PYH2_k127_1585537_4 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 546.0
PYH2_k127_1585537_5 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 511.0
PYH2_k127_1585537_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 471.0
PYH2_k127_1585537_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 312.0
PYH2_k127_1585537_8 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000133 231.0
PYH2_k127_1585537_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000005598 224.0
PYH2_k127_175879_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 553.0
PYH2_k127_175879_1 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 381.0
PYH2_k127_175879_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 352.0
PYH2_k127_175879_3 PFAM transposase IS3 IS911 family protein K07497 - - 0.000000000000000000000000000004979 121.0
PYH2_k127_175879_4 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000007728 126.0
PYH2_k127_175879_5 - - - - 0.000000000000000000000000004893 121.0
PYH2_k127_175879_6 Cytochrome P460 - - - 0.000000000000000000000000007666 113.0
PYH2_k127_175879_7 - - - - 0.0000001462 62.0
PYH2_k127_175879_8 PBS lyase HEAT-like repeat - - - 0.000003342 60.0
PYH2_k127_1800570_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008117 246.0
PYH2_k127_1800570_1 Transposase DDE domain group 1 - - - 0.00004519 48.0
PYH2_k127_1830843_0 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 602.0
PYH2_k127_1830843_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 424.0
PYH2_k127_1830843_2 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 354.0
PYH2_k127_1830843_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003157 289.0
PYH2_k127_1830843_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003497 248.0
PYH2_k127_1830843_5 - - - - 0.000000000000000000000000000000000000000000000001168 192.0
PYH2_k127_1865740_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1484.0
PYH2_k127_1865740_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1432.0
PYH2_k127_1865740_10 His Kinase A (phosphoacceptor) domain K02484,K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001852 282.0
PYH2_k127_1865740_11 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 258.0
PYH2_k127_1865740_12 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004264 275.0
PYH2_k127_1865740_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006062 270.0
PYH2_k127_1865740_14 von Willebrand factor, type A - - - 0.0000000000000000000000000000000004284 147.0
PYH2_k127_1865740_15 chaperone-mediated protein complex assembly - - - 0.0000000000000000000000000000001179 137.0
PYH2_k127_1865740_16 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000001341 129.0
PYH2_k127_1865740_17 Stress responsive - - - 0.00000000000000000000000000003392 121.0
PYH2_k127_1865740_18 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000003639 120.0
PYH2_k127_1865740_19 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000002976 117.0
PYH2_k127_1865740_2 Glycosyltransferase like family 2 - - - 2.055e-299 938.0
PYH2_k127_1865740_20 4Fe-4S binding domain - - - 0.0000000000000000000001362 101.0
PYH2_k127_1865740_21 component of anaerobic dehydrogenases - - - 0.000008583 56.0
PYH2_k127_1865740_3 Domain of unknown function (DUF5107) - - - 4.706e-260 842.0
PYH2_k127_1865740_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 524.0
PYH2_k127_1865740_5 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 503.0
PYH2_k127_1865740_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 417.0
PYH2_k127_1865740_7 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 428.0
PYH2_k127_1865740_8 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 415.0
PYH2_k127_1865740_9 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 291.0
PYH2_k127_1895184_0 alpha-L-rhamnosidase - - - 0.0 1415.0
PYH2_k127_1895184_1 Vault protein inter-alpha-trypsin domain K07114 - - 5.058e-196 641.0
PYH2_k127_1895184_10 acid phosphatase activity K22390 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 318.0
PYH2_k127_1895184_11 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 309.0
PYH2_k127_1895184_12 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 306.0
PYH2_k127_1895184_13 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 297.0
PYH2_k127_1895184_14 Spore coat protein CotH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001346 300.0
PYH2_k127_1895184_15 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000105 279.0
PYH2_k127_1895184_16 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000002477 251.0
PYH2_k127_1895184_17 phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000001274 195.0
PYH2_k127_1895184_18 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000002355 181.0
PYH2_k127_1895184_19 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000001376 150.0
PYH2_k127_1895184_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 535.0
PYH2_k127_1895184_20 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000006053 118.0
PYH2_k127_1895184_21 Domain of unknown function (DUF4956) - - - 0.00000000000000001227 93.0
PYH2_k127_1895184_22 alpha-ribazole phosphatase activity - - - 0.0000000009256 63.0
PYH2_k127_1895184_23 catechol 1,2-dioxygenase - - - 0.0000001027 61.0
PYH2_k127_1895184_24 catechol 1,2-dioxygenase K03381 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006725,GO:0008150,GO:0008152,GO:0008199,GO:0009056,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0018576,GO:0018958,GO:0019114,GO:0019336,GO:0019439,GO:0019614,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.13.11.1 0.0000005539 52.0
PYH2_k127_1895184_25 ABC-type antimicrobial peptide transport system, permease component - - - 0.000001297 55.0
PYH2_k127_1895184_26 - - - - 0.000167 53.0
PYH2_k127_1895184_27 MacB-like periplasmic core domain - - - 0.0003215 45.0
PYH2_k127_1895184_28 serine threonine protein kinase - - - 0.0009272 47.0
PYH2_k127_1895184_3 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 538.0
PYH2_k127_1895184_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 427.0
PYH2_k127_1895184_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 417.0
PYH2_k127_1895184_6 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 404.0
PYH2_k127_1895184_7 Alpha-L-fucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 392.0
PYH2_k127_1895184_8 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 372.0
PYH2_k127_1895184_9 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 361.0
PYH2_k127_1949564_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 319.0
PYH2_k127_1949564_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008979 250.0
PYH2_k127_1949564_2 PFAM short-chain dehydrogenase reductase SDR K05711 - 1.3.1.87 0.000000000549 60.0
PYH2_k127_1968600_0 Domain of unknown function (DUF4091) - - - 3.672e-225 712.0
PYH2_k127_1968600_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 526.0
PYH2_k127_1968600_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000006467 71.0
PYH2_k127_1968600_2 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 323.0
PYH2_k127_1968600_3 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 314.0
PYH2_k127_1968600_4 exodeoxyribonuclease I activity K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 302.0
PYH2_k127_1968600_5 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006668 281.0
PYH2_k127_1968600_6 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003958 241.0
PYH2_k127_1968600_7 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000007517 220.0
PYH2_k127_1968600_8 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000002787 179.0
PYH2_k127_1968600_9 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.0000000000000000000000000007499 123.0
PYH2_k127_1986658_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 406.0
PYH2_k127_1986658_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 366.0
PYH2_k127_1986658_2 component of anaerobic dehydrogenases - - - 0.0000000003156 68.0
PYH2_k127_1986658_3 Polysulphide reductase, NrfD - - - 0.000000002333 64.0
PYH2_k127_1993453_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 8.278e-220 702.0
PYH2_k127_1993453_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 361.0
PYH2_k127_1993453_10 PFAM flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000000000000146 177.0
PYH2_k127_1993453_11 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000458 168.0
PYH2_k127_1993453_12 HDOD domain - - - 0.0000000000000000000000000000000000000000009352 168.0
PYH2_k127_1993453_13 Flagellar rod assembly protein muramidase FlgJ K02395,K08259,K08309,K21472 - 3.4.24.75 0.0000000000000000000000000000000000006184 150.0
PYH2_k127_1993453_14 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000003868 143.0
PYH2_k127_1993453_15 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000195 131.0
PYH2_k127_1993453_16 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000006164 104.0
PYH2_k127_1993453_17 TIGRFAM flagellar biosynthetic protein FliS K02422 - - 0.0000000000000000001534 94.0
PYH2_k127_1993453_18 Role in flagellar biosynthesis K02420 - - 0.00000000000000004885 85.0
PYH2_k127_1993453_19 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000005514 89.0
PYH2_k127_1993453_2 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 336.0
PYH2_k127_1993453_20 A translational regulator that binds mRNA to regulate translation initiation and or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome- binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW K03563 - - 0.000000000000003412 77.0
PYH2_k127_1993453_21 General secretory system II, protein E domain protein K02652 - - 0.00000000000006534 82.0
PYH2_k127_1993453_22 SAF K02386 - - 0.000000000003537 77.0
PYH2_k127_1993453_23 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) K02398 - - 0.00000001412 60.0
PYH2_k127_1993453_24 PFAM FlgN - - - 0.00000009611 60.0
PYH2_k127_1993453_25 Flagellar biosynthesis protein, FliO K02418 - - 0.000078 52.0
PYH2_k127_1993453_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K13820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005033 282.0
PYH2_k127_1993453_4 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009441 269.0
PYH2_k127_1993453_5 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000141 265.0
PYH2_k127_1993453_6 flagellar hook-associated protein K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007791 269.0
PYH2_k127_1993453_7 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004991 259.0
PYH2_k127_1993453_8 bacterial-type flagellum organization K02282,K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000005482 241.0
PYH2_k127_1993453_9 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000004357 196.0
PYH2_k127_1996675_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 2.223e-198 634.0
PYH2_k127_1996675_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 584.0
PYH2_k127_1996675_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.0009151 50.0
PYH2_k127_199827_0 Carboxypeptidase regulatory-like domain - - - 1.188e-317 1007.0
PYH2_k127_199827_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 532.0
PYH2_k127_199827_10 Methyltransferase small domain K15460 - 2.1.1.223 0.000000000000000000000000000000002139 138.0
PYH2_k127_199827_12 - - - - 0.000000000000000000000000001159 118.0
PYH2_k127_199827_13 beta-lactamase - - - 0.00000000000000000000000001229 116.0
PYH2_k127_199827_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 527.0
PYH2_k127_199827_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 442.0
PYH2_k127_199827_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 374.0
PYH2_k127_199827_5 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 320.0
PYH2_k127_199827_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000008587 245.0
PYH2_k127_199827_7 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000899 218.0
PYH2_k127_199827_8 YHYH protein - - - 0.0000000000000000000000000000000001154 138.0
PYH2_k127_199827_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000003031 142.0
PYH2_k127_2042094_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 462.0
PYH2_k127_2042094_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 421.0
PYH2_k127_2042094_2 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 329.0
PYH2_k127_2043664_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 0.0 1080.0
PYH2_k127_2043664_1 L-fucose isomerase, C-terminal domain - - - 8.543e-228 713.0
PYH2_k127_2043664_2 BON domain - - - 0.0000000000000000000000000000000000000000000002876 173.0
PYH2_k127_2043664_3 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000004316 64.0
PYH2_k127_2063416_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 592.0
PYH2_k127_2063416_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 538.0
PYH2_k127_2063416_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 391.0
PYH2_k127_2063416_3 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000001916 112.0
PYH2_k127_2152843_0 lipolytic protein G-D-S-L family - - - 0.0 1007.0
PYH2_k127_2152843_1 Tricorn protease homolog - - - 4.491e-288 898.0
PYH2_k127_2152843_10 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 473.0
PYH2_k127_2152843_11 Copper resistance protein D K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 455.0
PYH2_k127_2152843_12 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 443.0
PYH2_k127_2152843_13 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 424.0
PYH2_k127_2152843_14 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 402.0
PYH2_k127_2152843_15 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 388.0
PYH2_k127_2152843_16 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 368.0
PYH2_k127_2152843_17 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01639 - 4.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 364.0
PYH2_k127_2152843_18 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 332.0
PYH2_k127_2152843_19 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000001255 160.0
PYH2_k127_2152843_2 Beta-L-arabinofuranosidase, GH127 - - - 4.339e-247 783.0
PYH2_k127_2152843_20 CopC domain - - - 0.00000000000000000000000001745 114.0
PYH2_k127_2152843_21 Protein of unknown function (DUF2911) - - - 0.0000000000008981 78.0
PYH2_k127_2152843_22 Antitoxin component of a type II toxin-antitoxin (TA) system. Upon K19687 GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000001988 70.0
PYH2_k127_2152843_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.099e-227 723.0
PYH2_k127_2152843_4 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 5.104e-222 707.0
PYH2_k127_2152843_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 620.0
PYH2_k127_2152843_6 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 568.0
PYH2_k127_2152843_7 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 527.0
PYH2_k127_2152843_8 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 496.0
PYH2_k127_2152843_9 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 484.0
PYH2_k127_2161962_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 2045.0
PYH2_k127_2161962_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067,K18118 - 2.8.3.18,3.1.2.1 5.718e-256 797.0
PYH2_k127_2161962_10 thiolester hydrolase activity K06889,K07000 - - 0.00000000000000000000000000000000000000000000000000000009505 203.0
PYH2_k127_2161962_11 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000002463 115.0
PYH2_k127_2161962_12 response to heat K07090 - - 0.000000001763 64.0
PYH2_k127_2161962_15 - - - - 0.00001884 48.0
PYH2_k127_2161962_2 acyl-CoA dehydrogenase activity - - - 2.513e-226 715.0
PYH2_k127_2161962_3 SAF K01708 - 4.2.1.42 1.425e-218 684.0
PYH2_k127_2161962_4 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 1.184e-206 651.0
PYH2_k127_2161962_5 GntP family permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 552.0
PYH2_k127_2161962_6 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 529.0
PYH2_k127_2161962_7 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 397.0
PYH2_k127_2161962_8 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001057 257.0
PYH2_k127_2192844_0 glycosyl hydrolase of K09955 - - 0.00000000000000000000000000000000000000000006767 184.0
PYH2_k127_2192844_1 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000004965 142.0
PYH2_k127_2211817_0 COG3335 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 479.0
PYH2_k127_2211817_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000004153 111.0
PYH2_k127_2211817_2 - - - - 0.0000000000000000001078 91.0
PYH2_k127_2211817_4 PFAM YHS domain - - - 0.00000001381 57.0
PYH2_k127_2228374_0 lysine biosynthetic process via aminoadipic acid - - - 1.98e-233 743.0
PYH2_k127_2228374_1 DinB family - - - 0.000000000000000000000000000000008958 136.0
PYH2_k127_2239833_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1188.0
PYH2_k127_2239833_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 513.0
PYH2_k127_2239833_10 Acetyl xylan esterase (AXE1) K01060 - 3.1.1.41 0.000000149 65.0
PYH2_k127_2239833_2 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 453.0
PYH2_k127_2239833_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 400.0
PYH2_k127_2239833_4 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
PYH2_k127_2239833_5 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
PYH2_k127_2239833_6 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
PYH2_k127_2239833_7 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000005098 175.0
PYH2_k127_2239833_8 xyloglucan:xyloglucosyl transferase activity - - - 0.00000000000000000000000000000000000000000002576 176.0
PYH2_k127_2239833_9 FtsX-like permease family K02004 - - 0.00000000000000000000000006021 111.0
PYH2_k127_2240057_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.651e-280 864.0
PYH2_k127_2240057_1 Hypothetical methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 422.0
PYH2_k127_2240057_2 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 346.0
PYH2_k127_2240057_3 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.0000000000001811 72.0
PYH2_k127_2240057_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000004871 61.0
PYH2_k127_2240057_5 Carboxypeptidase regulatory-like domain - - - 0.0008835 45.0
PYH2_k127_2250720_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 383.0
PYH2_k127_2250720_1 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000007077 209.0
PYH2_k127_2250720_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000006347 127.0
PYH2_k127_2250720_3 - - - - 0.000000000005084 76.0
PYH2_k127_2250720_4 PFAM Trehalose utilisation - - - 0.0001416 44.0
PYH2_k127_2253899_0 Peptidase U32 K08303 - - 0.0 1092.0
PYH2_k127_2253899_1 amino acid - - - 7.861e-236 747.0
PYH2_k127_2253899_10 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000002058 165.0
PYH2_k127_2253899_11 NIPSNAP - - - 0.000000000000000000000000000000001264 131.0
PYH2_k127_2253899_12 Tellurite resistance protein TerB - - - 0.0000000000000000000007776 110.0
PYH2_k127_2253899_13 Flagellar protein YcgR - - - 0.00000000000006771 81.0
PYH2_k127_2253899_14 AhpC/TSA family K03386 - 1.11.1.15 0.0000000000000906 76.0
PYH2_k127_2253899_15 Evidence 4 Homologs of previously reported genes of - - - 0.00000005565 62.0
PYH2_k127_2253899_16 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000113 55.0
PYH2_k127_2253899_2 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 524.0
PYH2_k127_2253899_3 L-fucose isomerase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 479.0
PYH2_k127_2253899_5 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 336.0
PYH2_k127_2253899_6 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 337.0
PYH2_k127_2253899_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000001764 223.0
PYH2_k127_2253899_8 PFAM Pyruvate kinase barrel K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000191 209.0
PYH2_k127_2253899_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000001198 190.0
PYH2_k127_2283859_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 300.0
PYH2_k127_2283859_1 phosphatase (DUF442) - - - 0.0000000000000000007234 94.0
PYH2_k127_2283859_2 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00001726 51.0
PYH2_k127_2305201_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 530.0
PYH2_k127_2305201_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 429.0
PYH2_k127_2305201_10 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000005449 149.0
PYH2_k127_2305201_11 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000001275 128.0
PYH2_k127_2305201_12 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.0000000000000000000000000008173 123.0
PYH2_k127_2305201_13 Lipopolysaccharide-assembly - - - 0.000000000000000000000000001944 121.0
PYH2_k127_2305201_14 - - - - 0.000000000000000000000977 104.0
PYH2_k127_2305201_15 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.000000000000005915 77.0
PYH2_k127_2305201_16 Binds directly to 16S ribosomal RNA K02968 - - 0.00000005622 57.0
PYH2_k127_2305201_17 Protein of unknown function (DUF465) K09794 - - 0.00002301 49.0
PYH2_k127_2305201_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 369.0
PYH2_k127_2305201_3 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 359.0
PYH2_k127_2305201_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000002152 226.0
PYH2_k127_2305201_5 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000116 215.0
PYH2_k127_2305201_6 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000001255 209.0
PYH2_k127_2305201_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000005207 186.0
PYH2_k127_2305201_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000004897 186.0
PYH2_k127_2305201_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000004765 187.0
PYH2_k127_2318220_0 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 432.0
PYH2_k127_2318220_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000002913 170.0
PYH2_k127_2325761_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 593.0
PYH2_k127_2325761_1 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
PYH2_k127_2325761_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 388.0
PYH2_k127_2325761_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005184 304.0
PYH2_k127_2325761_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000005016 196.0
PYH2_k127_2325761_5 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000006982 126.0
PYH2_k127_2325761_6 hydrogenase maturation protease - - - 0.000000000000000000000004092 111.0
PYH2_k127_2359594_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2181.0
PYH2_k127_2359594_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.36e-248 780.0
PYH2_k127_2359594_10 - - - - 0.000000000000000000000000004056 122.0
PYH2_k127_2359594_11 Belongs to the glycosyl hydrolase 32 family - - - 0.0000000000000000003081 100.0
PYH2_k127_2359594_2 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.611e-239 750.0
PYH2_k127_2359594_3 dipeptidase activity - - - 2.141e-219 692.0
PYH2_k127_2359594_4 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 413.0
PYH2_k127_2359594_5 COG0583 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002432 279.0
PYH2_k127_2359594_6 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 282.0
PYH2_k127_2359594_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000002359 250.0
PYH2_k127_2359594_8 - K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000004467 244.0
PYH2_k127_2359594_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006563 236.0
PYH2_k127_2401899_0 symporter activity K03307,K11928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 529.0
PYH2_k127_2401899_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
PYH2_k127_2401899_2 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000023 288.0
PYH2_k127_2401899_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005119 238.0
PYH2_k127_2401899_4 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000001597 134.0
PYH2_k127_2401899_5 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000001616 140.0
PYH2_k127_2401899_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000001574 79.0
PYH2_k127_2401899_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000000005082 74.0
PYH2_k127_24101_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 322.0
PYH2_k127_24101_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000001172 234.0
PYH2_k127_24101_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000004548 82.0
PYH2_k127_2411136_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
PYH2_k127_2412817_0 zinc ion binding K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 574.0
PYH2_k127_2412817_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002659 240.0
PYH2_k127_2412817_2 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000001315 121.0
PYH2_k127_2412817_3 myo-inosose-2 dehydratase activity - - - 0.000000000000000000005792 101.0
PYH2_k127_2412817_4 Belongs to the Dps family K04047 - - 0.00004956 48.0
PYH2_k127_2412817_5 myo-inosose-2 dehydratase activity - - - 0.00008326 45.0
PYH2_k127_2424505_0 radical SAM domain protein - - - 2.244e-279 871.0
PYH2_k127_2424505_1 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 592.0
PYH2_k127_2424505_10 antisigma factor binding K04749 - - 0.000000000000000008728 91.0
PYH2_k127_2424505_11 diguanylate cyclase - - - 0.00000000000000002552 93.0
PYH2_k127_2424505_12 MlaD protein K02067 - - 0.00000006833 64.0
PYH2_k127_2424505_13 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000004162 58.0
PYH2_k127_2424505_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 547.0
PYH2_k127_2424505_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
PYH2_k127_2424505_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 295.0
PYH2_k127_2424505_5 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001269 289.0
PYH2_k127_2424505_6 AI-2E family transporter - - - 0.000000000000000000000000000000002969 142.0
PYH2_k127_2424505_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000003689 121.0
PYH2_k127_2424505_8 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000004484 100.0
PYH2_k127_2424505_9 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000775 101.0
PYH2_k127_24418_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.626e-262 826.0
PYH2_k127_24418_1 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 1.421e-243 765.0
PYH2_k127_24418_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001166 218.0
PYH2_k127_24418_11 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000001067 178.0
PYH2_k127_24418_12 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000006877 164.0
PYH2_k127_24418_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000054 144.0
PYH2_k127_24418_14 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000007455 143.0
PYH2_k127_24418_15 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000005774 119.0
PYH2_k127_24418_16 Glycosyl transferases group 1 - - - 0.0000000000000000000001664 110.0
PYH2_k127_24418_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001718 85.0
PYH2_k127_24418_18 amine dehydrogenase activity - - - 0.00000000000001001 89.0
PYH2_k127_24418_19 Winged helix-turn-helix DNA-binding - - - 0.000000000000413 78.0
PYH2_k127_24418_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 470.0
PYH2_k127_24418_20 PFAM NHL repeat containing protein - - - 0.0000002778 64.0
PYH2_k127_24418_21 Belongs to the 5'-nucleotidase family K17224 - - 0.0001244 53.0
PYH2_k127_24418_22 COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives - - - 0.0007783 46.0
PYH2_k127_24418_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 404.0
PYH2_k127_24418_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 380.0
PYH2_k127_24418_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 366.0
PYH2_k127_24418_6 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 319.0
PYH2_k127_24418_7 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 289.0
PYH2_k127_24418_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000003123 265.0
PYH2_k127_24418_9 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000009004 256.0
PYH2_k127_2475205_0 SMART Resolvase, RNase H domain protein fold K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 616.0
PYH2_k127_247609_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 440.0
PYH2_k127_247609_1 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000001666 138.0
PYH2_k127_247609_2 - - - - 0.000000000001 74.0
PYH2_k127_247774_0 Ketoacyl-synthetase C-terminal extension - - - 4.991e-317 997.0
PYH2_k127_247774_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.434e-230 722.0
PYH2_k127_247774_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 400.0
PYH2_k127_247774_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 400.0
PYH2_k127_247774_12 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 380.0
PYH2_k127_247774_13 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 378.0
PYH2_k127_247774_14 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 374.0
PYH2_k127_247774_15 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 356.0
PYH2_k127_247774_16 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 342.0
PYH2_k127_247774_17 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 342.0
PYH2_k127_247774_18 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 327.0
PYH2_k127_247774_19 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
PYH2_k127_247774_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 8.018e-226 707.0
PYH2_k127_247774_20 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 305.0
PYH2_k127_247774_21 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 294.0
PYH2_k127_247774_22 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 290.0
PYH2_k127_247774_23 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004541 292.0
PYH2_k127_247774_24 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000372 259.0
PYH2_k127_247774_25 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001138 253.0
PYH2_k127_247774_26 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003852 250.0
PYH2_k127_247774_27 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000002366 221.0
PYH2_k127_247774_28 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000007773 215.0
PYH2_k127_247774_29 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000024 185.0
PYH2_k127_247774_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 7.526e-211 666.0
PYH2_k127_247774_30 Rhomboid family - - - 0.00000000000000000000000000000000000000000000002433 179.0
PYH2_k127_247774_31 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000000000000006187 163.0
PYH2_k127_247774_32 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000006687 147.0
PYH2_k127_247774_33 PFAM Phosphoribosyltransferase K02242 - - 0.00000000000000000000000000000000000008593 152.0
PYH2_k127_247774_34 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000002264 147.0
PYH2_k127_247774_35 methyltransferase - - - 0.00000000000000000000000000000000001192 152.0
PYH2_k127_247774_36 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000768 134.0
PYH2_k127_247774_37 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000002201 125.0
PYH2_k127_247774_38 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000008832 123.0
PYH2_k127_247774_39 protein TIM barrel - - - 0.0000000000000000000000000001012 131.0
PYH2_k127_247774_4 Pfam:DUF1237 K09704 - - 1.618e-202 640.0
PYH2_k127_247774_40 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000004691 119.0
PYH2_k127_247774_41 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000002423 118.0
PYH2_k127_247774_42 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000007948 113.0
PYH2_k127_247774_43 Cold shock protein K03704 - - 0.00000000000000000000000007261 108.0
PYH2_k127_247774_44 - - - - 0.0000000000000000000000005272 110.0
PYH2_k127_247774_45 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001145 111.0
PYH2_k127_247774_46 Phage integrase family - - - 0.00000000000000000000002781 109.0
PYH2_k127_247774_47 Cell division protein FtsQ K03589 - - 0.0000000000000000000004876 107.0
PYH2_k127_247774_48 Redoxin K03564 - 1.11.1.15 0.0000000000000000000363 93.0
PYH2_k127_247774_49 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000000000000000003994 102.0
PYH2_k127_247774_5 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 561.0
PYH2_k127_247774_50 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000008473 93.0
PYH2_k127_247774_51 peroxiredoxin activity K03564,K17275 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019430,GO:0019725,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0045454,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0051920,GO:0055114,GO:0061687,GO:0061691,GO:0061692,GO:0065007,GO:0065008,GO:0070301,GO:0070887,GO:0071236,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.11.1.15 0.000000000001494 70.0
PYH2_k127_247774_52 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000001472 59.0
PYH2_k127_247774_54 - - - - 0.000007137 53.0
PYH2_k127_247774_55 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00004065 55.0
PYH2_k127_247774_56 - - - - 0.0001569 48.0
PYH2_k127_247774_57 HEAT repeats - - - 0.0002588 50.0
PYH2_k127_247774_6 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 497.0
PYH2_k127_247774_7 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 467.0
PYH2_k127_247774_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 429.0
PYH2_k127_247774_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 413.0
PYH2_k127_2529968_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.045e-293 908.0
PYH2_k127_2529968_1 DEAD DEAH box helicase K03654 - 3.6.4.12 3.525e-218 692.0
PYH2_k127_2529968_11 GDSL-like Lipase/Acylhydrolase - - - 0.0000007205 64.0
PYH2_k127_2529968_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.297e-201 644.0
PYH2_k127_2529968_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 602.0
PYH2_k127_2529968_4 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 514.0
PYH2_k127_2529968_5 tRNA m6t6A37 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
PYH2_k127_2529968_6 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000003289 177.0
PYH2_k127_2529968_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000006901 131.0
PYH2_k127_2529968_8 cell redox homeostasis K02199 - - 0.000000000000000000005741 98.0
PYH2_k127_2529968_9 - - - - 0.0000000000000000001041 90.0
PYH2_k127_2544169_0 - - - - 0.0 1058.0
PYH2_k127_2544169_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 592.0
PYH2_k127_2544169_10 von Willebrand factor, type A - - - 0.0000000000000000000000018 117.0
PYH2_k127_2544169_12 Malate/L-lactate dehydrogenase - - - 0.000000000001138 70.0
PYH2_k127_2544169_13 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.000000000002446 67.0
PYH2_k127_2544169_2 Domain of unknown function (DUF5107) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 560.0
PYH2_k127_2544169_3 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 530.0
PYH2_k127_2544169_4 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 508.0
PYH2_k127_2544169_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 436.0
PYH2_k127_2544169_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 351.0
PYH2_k127_2544169_7 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000005475 223.0
PYH2_k127_2544169_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000564 165.0
PYH2_k127_2544169_9 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000001591 143.0
PYH2_k127_2576293_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1334.0
PYH2_k127_2576293_1 Heat shock 70 kDa protein K04043 - - 7.372e-300 931.0
PYH2_k127_2576293_10 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 358.0
PYH2_k127_2576293_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 358.0
PYH2_k127_2576293_12 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 366.0
PYH2_k127_2576293_13 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 342.0
PYH2_k127_2576293_14 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
PYH2_k127_2576293_15 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 357.0
PYH2_k127_2576293_16 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 332.0
PYH2_k127_2576293_17 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 315.0
PYH2_k127_2576293_18 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 297.0
PYH2_k127_2576293_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000003266 213.0
PYH2_k127_2576293_2 amino acid K03294 - - 2.357e-249 781.0
PYH2_k127_2576293_20 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000006394 205.0
PYH2_k127_2576293_21 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000773 166.0
PYH2_k127_2576293_22 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000001471 176.0
PYH2_k127_2576293_23 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001327 163.0
PYH2_k127_2576293_24 Transcription termination factor nusG - - - 0.00000000000000000000000000000000000007865 149.0
PYH2_k127_2576293_25 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000000000001184 139.0
PYH2_k127_2576293_26 Roadblock/LC7 domain - - - 0.000000000000000000000000003195 120.0
PYH2_k127_2576293_27 Tetratricopeptide repeat - - - 0.000000000001113 79.0
PYH2_k127_2576293_28 von Willebrand factor, type A - - - 0.0000000003247 72.0
PYH2_k127_2576293_29 Putative regulatory protein - - - 0.0000001311 61.0
PYH2_k127_2576293_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.132e-216 677.0
PYH2_k127_2576293_4 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 591.0
PYH2_k127_2576293_5 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 534.0
PYH2_k127_2576293_6 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 497.0
PYH2_k127_2576293_7 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 481.0
PYH2_k127_2576293_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 429.0
PYH2_k127_2576293_9 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 409.0
PYH2_k127_259130_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.816e-270 842.0
PYH2_k127_259130_1 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 444.0
PYH2_k127_263962_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 547.0
PYH2_k127_263962_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 485.0
PYH2_k127_263962_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 426.0
PYH2_k127_263962_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 359.0
PYH2_k127_263962_5 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000002971 127.0
PYH2_k127_263962_6 Trypsin K04691 - - 0.00000000000001973 84.0
PYH2_k127_263962_7 - - - - 0.0000000000000317 81.0
PYH2_k127_2745831_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 601.0
PYH2_k127_2745831_1 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 482.0
PYH2_k127_2745831_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000005985 213.0
PYH2_k127_2745831_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000319 182.0
PYH2_k127_2745831_12 structural constituent of ribosome K02996 - - 0.000000000000000000000000000000000000000000007405 166.0
PYH2_k127_2745831_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000539 122.0
PYH2_k127_2745831_14 Pilus assembly protein, PilO K02664 - - 0.00000000000000002784 89.0
PYH2_k127_2745831_15 assembly protein (PilN) K02663 - - 0.000000000006571 74.0
PYH2_k127_2745831_2 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 433.0
PYH2_k127_2745831_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 353.0
PYH2_k127_2745831_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 327.0
PYH2_k127_2745831_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 319.0
PYH2_k127_2745831_6 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001907 296.0
PYH2_k127_2745831_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004839 250.0
PYH2_k127_2745831_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001595 248.0
PYH2_k127_2745831_9 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000004996 226.0
PYH2_k127_2801075_0 ATPase BadF BadG BcrA BcrD type - - - 8.19e-229 758.0
PYH2_k127_2801075_1 ErfK YbiS YcfS YnhG family protein K21470 - - 1.299e-206 661.0
PYH2_k127_2801075_2 COG1073 Hydrolases of the alpha beta superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 515.0
PYH2_k127_2801075_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003755 267.0
PYH2_k127_2801075_4 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
PYH2_k127_2801075_5 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 234.0
PYH2_k127_2801075_6 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000001282 235.0
PYH2_k127_2803214_0 Peptidase S46 - - - 0.0 1192.0
PYH2_k127_2803214_1 Sodium:solute symporter family - - - 1.167e-305 945.0
PYH2_k127_2803214_10 RnfC Barrel sandwich hybrid domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 385.0
PYH2_k127_2803214_11 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 376.0
PYH2_k127_2803214_12 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 376.0
PYH2_k127_2803214_13 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 351.0
PYH2_k127_2803214_14 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 346.0
PYH2_k127_2803214_15 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 303.0
PYH2_k127_2803214_16 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 301.0
PYH2_k127_2803214_17 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002126 285.0
PYH2_k127_2803214_18 propanediol catabolic process K15024 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452 280.0
PYH2_k127_2803214_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006503 270.0
PYH2_k127_2803214_2 ABC transporter K06020 - 3.6.3.25 4.768e-270 842.0
PYH2_k127_2803214_20 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000003489 233.0
PYH2_k127_2803214_21 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000149 234.0
PYH2_k127_2803214_22 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000006473 226.0
PYH2_k127_2803214_23 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000004008 213.0
PYH2_k127_2803214_24 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000002806 211.0
PYH2_k127_2803214_25 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000269 208.0
PYH2_k127_2803214_26 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000000000000000000000000000001564 189.0
PYH2_k127_2803214_27 BMC K04025 - - 0.0000000000000000000000000000000000000000000000003762 181.0
PYH2_k127_2803214_28 Cysteine-rich domain K00113 - 1.1.5.3 0.000000000000000000000000002961 111.0
PYH2_k127_2803214_29 TIGRFAM methyltransferase FkbM - - - 0.00000000000000000000006545 110.0
PYH2_k127_2803214_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 5.155e-269 848.0
PYH2_k127_2803214_30 DNA-templated transcription, initiation K03088 - - 0.000000000000000004747 91.0
PYH2_k127_2803214_31 Protein of unknown function (DUF2934) - - - 0.0000007104 57.0
PYH2_k127_2803214_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 523.0
PYH2_k127_2803214_5 Galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 479.0
PYH2_k127_2803214_6 2-epimerase K16213 - 5.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 476.0
PYH2_k127_2803214_7 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 437.0
PYH2_k127_2803214_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 430.0
PYH2_k127_2803214_9 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 400.0
PYH2_k127_2809641_0 Penicillin amidase K01434 - 3.5.1.11 1.038e-311 966.0
PYH2_k127_2809641_1 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 556.0
PYH2_k127_2809641_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001431 106.0
PYH2_k127_2809641_11 Putative transposase - - - 0.000000000000000000001054 99.0
PYH2_k127_2809641_12 Protein of unknown function (DUF418) K07148 - - 0.00000000004067 64.0
PYH2_k127_2809641_13 L-fucose isomerase and related - - - 0.000000000594 62.0
PYH2_k127_2809641_14 BlaR1 peptidase M56 - - - 0.00000002971 55.0
PYH2_k127_2809641_15 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0004876 49.0
PYH2_k127_2809641_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 449.0
PYH2_k127_2809641_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
PYH2_k127_2809641_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006019 262.0
PYH2_k127_2809641_5 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 243.0
PYH2_k127_2809641_6 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000119 206.0
PYH2_k127_2809641_7 heat shock protein binding K03686 - - 0.000000000000000000000000000000000000000000005419 173.0
PYH2_k127_2809641_8 - - - - 0.000000000000000000000000000000000004417 154.0
PYH2_k127_2809641_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000003712 134.0
PYH2_k127_2843721_0 Tripartite tricarboxylate transporter TctA family K07793 - - 5.081e-208 657.0
PYH2_k127_2843721_1 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 327.0
PYH2_k127_2843721_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000001222 224.0
PYH2_k127_2843721_3 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000777 214.0
PYH2_k127_2843721_4 - - - - 0.0000000000000000000000000000000000000000000004541 178.0
PYH2_k127_2843721_5 membrane K07794 - - 0.0000000002645 68.0
PYH2_k127_2845968_0 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000008536 190.0
PYH2_k127_2855003_0 Heat shock 70 kDa protein K04043 - - 1.198e-215 686.0
PYH2_k127_2855003_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.502e-204 654.0
PYH2_k127_2855003_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000003737 199.0
PYH2_k127_2855003_11 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000001639 191.0
PYH2_k127_2855003_12 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000001705 159.0
PYH2_k127_2855003_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000002513 129.0
PYH2_k127_2855003_14 DUF167 K09131 - - 0.000000000000000000004939 96.0
PYH2_k127_2855003_15 - - - - 0.00000000000000008795 94.0
PYH2_k127_2855003_16 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000001781 86.0
PYH2_k127_2855003_18 Serine threonine protein kinase - - - 0.0001998 54.0
PYH2_k127_2855003_2 Radical SAM - - - 1.576e-197 627.0
PYH2_k127_2855003_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 497.0
PYH2_k127_2855003_4 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 503.0
PYH2_k127_2855003_5 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 423.0
PYH2_k127_2855003_6 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 415.0
PYH2_k127_2855003_7 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 308.0
PYH2_k127_2855003_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004377 259.0
PYH2_k127_2855003_9 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000006318 252.0
PYH2_k127_2857471_0 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 338.0
PYH2_k127_2857471_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 319.0
PYH2_k127_2857471_2 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000404 283.0
PYH2_k127_2860476_0 Aminotransferase K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 490.0
PYH2_k127_2860476_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
PYH2_k127_2860476_2 Aminotransferase K00841 - - 0.00000000000000000000001072 119.0
PYH2_k127_2860476_3 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.0000002378 55.0
PYH2_k127_2883595_0 PFAM Major facilitator superfamily K02429 - - 8.646e-212 667.0
PYH2_k127_2883595_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000002452 60.0
PYH2_k127_2910266_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 485.0
PYH2_k127_2910266_1 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 419.0
PYH2_k127_2910266_2 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 265.0
PYH2_k127_2910266_3 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001012 244.0
PYH2_k127_2910266_4 Integrase core domain - - - 0.000000000000000000000000004171 114.0
PYH2_k127_2910266_6 DNA integration - - - 0.0000002721 64.0
PYH2_k127_2913810_0 import. Responsible for energy coupling to the transport system K17215 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 470.0
PYH2_k127_2913810_1 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 310.0
PYH2_k127_2913810_2 PFAM LIM, zinc-binding protein - - - 0.000000000000000000000000001855 124.0
PYH2_k127_2916877_0 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000000000838 231.0
PYH2_k127_2916877_1 Glucose / Sorbosone dehydrogenase K00428,K01083,K01728 - 1.11.1.5,3.1.3.8,4.2.2.2 0.000000000000000002977 101.0
PYH2_k127_2916877_2 Spore coat protein CotH - - - 0.00000000000003446 88.0
PYH2_k127_2916877_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000006421 80.0
PYH2_k127_2917056_0 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 514.0
PYH2_k127_2917056_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 421.0
PYH2_k127_2917056_2 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 367.0
PYH2_k127_2927655_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.137e-246 780.0
PYH2_k127_2927655_1 elongation factor Tu domain 2 protein K02355 - - 4.026e-234 743.0
PYH2_k127_2927655_2 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 355.0
PYH2_k127_2927655_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004443 285.0
PYH2_k127_2927655_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002752 275.0
PYH2_k127_2927655_5 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006667 255.0
PYH2_k127_2927655_6 selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000715 237.0
PYH2_k127_2927655_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000005208 236.0
PYH2_k127_2941550_0 Protein of unknown function (DUF559) - - - 0.0 1165.0
PYH2_k127_2941550_1 Oligogalacturonate lyase K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 581.0
PYH2_k127_2941550_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 360.0
PYH2_k127_2941550_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
PYH2_k127_2941550_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000004367 203.0
PYH2_k127_2941550_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000003836 153.0
PYH2_k127_2941550_6 MOSC domain - - - 0.000000000000000000000000000001879 123.0
PYH2_k127_2941550_7 competence protein - - - 0.00000000000000000000000000009833 127.0
PYH2_k127_2941550_8 DNA primase small subunit - - - 0.000000009093 69.0
PYH2_k127_2960650_0 Glycosyl hydrolase family 2, sugar binding domain protein - - - 0.0 1088.0
PYH2_k127_2960650_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 1.287e-213 682.0
PYH2_k127_2960650_10 MAC/Perforin domain - - - 0.00000000000001042 85.0
PYH2_k127_2960650_11 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000003409 76.0
PYH2_k127_2960650_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 611.0
PYH2_k127_2960650_3 Tricorn protease homolog - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 560.0
PYH2_k127_2960650_4 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 560.0
PYH2_k127_2960650_5 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 430.0
PYH2_k127_2960650_6 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 364.0
PYH2_k127_2960650_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 362.0
PYH2_k127_2960650_8 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004582 253.0
PYH2_k127_2960650_9 Jacalin-like lectin domain - - - 0.000000000000000000000000001204 125.0
PYH2_k127_2984308_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 417.0
PYH2_k127_2984308_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 333.0
PYH2_k127_2984308_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000001208 248.0
PYH2_k127_2984308_3 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.00000000001264 76.0
PYH2_k127_2999109_0 PFAM TonB-dependent Receptor Plug - - - 0.0 1325.0
PYH2_k127_2999109_1 ABC transporter K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 1.861e-284 885.0
PYH2_k127_2999109_11 oxidoreductase activity - - - 0.00007059 52.0
PYH2_k127_2999109_2 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 515.0
PYH2_k127_2999109_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 477.0
PYH2_k127_2999109_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 404.0
PYH2_k127_2999109_5 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 310.0
PYH2_k127_2999109_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000001889 195.0
PYH2_k127_2999109_7 PFAM Uncharacterised BCR, COG1649 K01448 - 3.5.1.28 0.00000000000000000000000000000000000001204 151.0
PYH2_k127_2999109_8 Beta-lactamase - - - 0.0000000000000000000000006125 115.0
PYH2_k127_2999109_9 Putative lumazine-binding - - - 0.00000000000000000006675 100.0
PYH2_k127_3010040_0 Carboxypeptidase regulatory-like domain - - - 3.965e-260 824.0
PYH2_k127_3010040_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 502.0
PYH2_k127_3023763_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.155e-307 980.0
PYH2_k127_3023763_1 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000001714 191.0
PYH2_k127_3023763_2 Flagellar protein YcgR - - - 0.00000002146 64.0
PYH2_k127_3026848_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 500.0
PYH2_k127_3026848_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000003257 205.0
PYH2_k127_3026848_2 - - - - 0.000000000000000000000000000000000000000000000000001111 188.0
PYH2_k127_3026848_3 DoxX K16937 - 1.8.5.2 0.00000000000000000000000000000000000006955 161.0
PYH2_k127_3029796_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
PYH2_k127_3029796_1 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000002432 146.0
PYH2_k127_3029796_2 oxidation-reduction process - - - 0.00000000000000000000000006093 110.0
PYH2_k127_3072137_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000001279 93.0
PYH2_k127_3120666_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.639e-197 642.0
PYH2_k127_3120666_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 370.0
PYH2_k127_3125804_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003908 243.0
PYH2_k127_3125804_1 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000001941 79.0
PYH2_k127_3126529_0 Hypothetical glycosyl hydrolase 6 - - - 7.679e-318 994.0
PYH2_k127_3126529_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.256e-289 907.0
PYH2_k127_3126529_10 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 296.0
PYH2_k127_3126529_11 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000178 279.0
PYH2_k127_3126529_12 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006991 276.0
PYH2_k127_3126529_13 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000002568 228.0
PYH2_k127_3126529_14 transport - - - 0.0000000000000000000000000000000000000000000009403 172.0
PYH2_k127_3126529_15 DinB family - - - 0.0000000000000000000000000000000000000003622 155.0
PYH2_k127_3126529_16 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000002079 151.0
PYH2_k127_3126529_17 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000004703 160.0
PYH2_k127_3126529_18 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000005767 138.0
PYH2_k127_3126529_2 Domain of unknown function (DUF1846) - - - 7.129e-248 774.0
PYH2_k127_3126529_20 Nitroreductase family - - - 0.0004856 52.0
PYH2_k127_3126529_3 oligopeptide transport K03305 - - 6.872e-230 721.0
PYH2_k127_3126529_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 564.0
PYH2_k127_3126529_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 502.0
PYH2_k127_3126529_6 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 466.0
PYH2_k127_3126529_7 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 425.0
PYH2_k127_3126529_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 412.0
PYH2_k127_3126529_9 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 409.0
PYH2_k127_3135464_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 375.0
PYH2_k127_3135464_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000117 194.0
PYH2_k127_3135464_2 chelatase, subunit chli K07391 - - 0.0000000000000000000000001509 107.0
PYH2_k127_3135464_3 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000001358 92.0
PYH2_k127_3137210_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 317.0
PYH2_k127_3137210_1 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000006272 92.0
PYH2_k127_3137210_2 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000003851 67.0
PYH2_k127_3137210_3 - - - - 0.00000001645 60.0
PYH2_k127_3161258_0 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 565.0
PYH2_k127_3161258_1 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 540.0
PYH2_k127_3161258_10 - - - - 0.0000000000000000000000000000004797 131.0
PYH2_k127_3161258_11 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000001164 64.0
PYH2_k127_3161258_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 427.0
PYH2_k127_3161258_3 Glycosyl hydrolase family 20, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 362.0
PYH2_k127_3161258_4 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003845 248.0
PYH2_k127_3161258_5 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000004269 204.0
PYH2_k127_3161258_6 NIPSNAP - - - 0.0000000000000000000000000000000000000000000001384 178.0
PYH2_k127_3161258_7 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000004677 166.0
PYH2_k127_3161258_8 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000004883 166.0
PYH2_k127_3161258_9 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.0000000000000000000000000000000000000000003755 178.0
PYH2_k127_3207485_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 1.229e-213 671.0
PYH2_k127_3207485_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 432.0
PYH2_k127_3207485_10 Redoxin - - - 0.00000000006874 63.0
PYH2_k127_3207485_11 Protein of unknown function (DUF1573) - - - 0.0000007465 57.0
PYH2_k127_3207485_12 Protein of unknown function (DUF1573) - - - 0.0003196 46.0
PYH2_k127_3207485_2 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 343.0
PYH2_k127_3207485_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 338.0
PYH2_k127_3207485_4 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 329.0
PYH2_k127_3207485_5 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000002555 139.0
PYH2_k127_3207485_6 esterase - - - 0.00000000000000000000000000000000001046 148.0
PYH2_k127_3207485_7 - - - - 0.0000000000000000000000000000001483 135.0
PYH2_k127_3207485_8 glycosyl transferase group 1 K00754 - - 0.000000000000000000002216 105.0
PYH2_k127_3207485_9 - - - - 0.000000000000000005508 91.0
PYH2_k127_3212136_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1124.0
PYH2_k127_3212136_1 PFAM glycoside hydrolase family 29 K01206 - 3.2.1.51 2.965e-221 696.0
PYH2_k127_3212136_10 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
PYH2_k127_3212136_11 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 398.0
PYH2_k127_3212136_12 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 423.0
PYH2_k127_3212136_13 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 389.0
PYH2_k127_3212136_14 Inosine-uridine preferring nucleoside hydrolase K01250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
PYH2_k127_3212136_15 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 369.0
PYH2_k127_3212136_16 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 361.0
PYH2_k127_3212136_17 Radical_SAM C-terminal domain K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 355.0
PYH2_k127_3212136_18 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
PYH2_k127_3212136_19 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 331.0
PYH2_k127_3212136_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 1.101e-208 672.0
PYH2_k127_3212136_20 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 304.0
PYH2_k127_3212136_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 292.0
PYH2_k127_3212136_22 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000006427 246.0
PYH2_k127_3212136_23 Iron-storage protein K02217 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
PYH2_k127_3212136_24 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000002714 221.0
PYH2_k127_3212136_25 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000565 220.0
PYH2_k127_3212136_26 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000006869 205.0
PYH2_k127_3212136_28 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000001053 184.0
PYH2_k127_3212136_29 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000001176 177.0
PYH2_k127_3212136_3 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 3.904e-195 620.0
PYH2_k127_3212136_30 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000001086 173.0
PYH2_k127_3212136_31 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000001844 160.0
PYH2_k127_3212136_32 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000004438 137.0
PYH2_k127_3212136_33 - - - - 0.000000000000000000000000003751 122.0
PYH2_k127_3212136_35 NUDIX domain - - - 0.000000000000008271 80.0
PYH2_k127_3212136_36 Psort location CytoplasmicMembrane, score - - - 0.00000000000002743 86.0
PYH2_k127_3212136_39 PA domain - - - 0.00001196 50.0
PYH2_k127_3212136_4 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 623.0
PYH2_k127_3212136_40 - - - - 0.0000585 47.0
PYH2_k127_3212136_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 586.0
PYH2_k127_3212136_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 553.0
PYH2_k127_3212136_7 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 487.0
PYH2_k127_3212136_8 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 443.0
PYH2_k127_3212136_9 GatB/GatE catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 437.0
PYH2_k127_3254508_0 Response regulator receiver - - - 1.395e-203 642.0
PYH2_k127_3254508_1 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 556.0
PYH2_k127_3254508_10 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 436.0
PYH2_k127_3254508_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 422.0
PYH2_k127_3254508_12 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 414.0
PYH2_k127_3254508_13 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 413.0
PYH2_k127_3254508_14 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 395.0
PYH2_k127_3254508_15 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 382.0
PYH2_k127_3254508_16 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 373.0
PYH2_k127_3254508_17 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 345.0
PYH2_k127_3254508_18 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000581 275.0
PYH2_k127_3254508_19 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000008152 264.0
PYH2_k127_3254508_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 544.0
PYH2_k127_3254508_20 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001277 267.0
PYH2_k127_3254508_21 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000007316 174.0
PYH2_k127_3254508_22 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000005161 164.0
PYH2_k127_3254508_23 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000005125 140.0
PYH2_k127_3254508_24 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000002788 124.0
PYH2_k127_3254508_25 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000008673 122.0
PYH2_k127_3254508_26 Glycosyl hydrolase-like 10 - - - 0.0000000000000002861 92.0
PYH2_k127_3254508_27 - - - - 0.000000001077 66.0
PYH2_k127_3254508_28 YtxH-like protein - - - 0.000000006329 63.0
PYH2_k127_3254508_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 555.0
PYH2_k127_3254508_4 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 532.0
PYH2_k127_3254508_5 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 531.0
PYH2_k127_3254508_6 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 520.0
PYH2_k127_3254508_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 468.0
PYH2_k127_3254508_8 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 460.0
PYH2_k127_3254508_9 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 458.0
PYH2_k127_3256597_0 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 316.0
PYH2_k127_3256597_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000001952 170.0
PYH2_k127_3256597_2 DEAD DEAH box helicase domain protein K06877 - - 0.0000000000000000000000000000000000008356 145.0
PYH2_k127_3256597_3 AAA domain - - - 0.0000000000000000000000000000001484 144.0
PYH2_k127_3256597_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000001691 123.0
PYH2_k127_3296764_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1335.0
PYH2_k127_3296764_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1042.0
PYH2_k127_3296764_2 Succinyl-CoA ligase like flavodoxin domain K09181 - - 2.294e-291 915.0
PYH2_k127_3296764_3 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 481.0
PYH2_k127_3296764_4 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
PYH2_k127_3302049_0 Tricorn protease homolog - - - 1.992e-287 897.0
PYH2_k127_3369742_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 539.0
PYH2_k127_3369742_1 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 295.0
PYH2_k127_3373066_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 299.0
PYH2_k127_3373066_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000003729 212.0
PYH2_k127_3373066_2 Fic/DOC family K07341 - - 0.00000000000000000000000000000000003705 139.0
PYH2_k127_3373066_3 ribonuclease activity - - - 0.00000000000000000000000000000718 125.0
PYH2_k127_3373066_4 - - - - 0.0000000000000000000000008298 111.0
PYH2_k127_3373066_5 polysaccharide deacetylase - - - 0.000000000000000000000004132 114.0
PYH2_k127_3373066_6 TIGRFAM methyltransferase FkbM - - - 0.00000000000000000000005279 108.0
PYH2_k127_3373066_8 PFAM SpoVT AbrB K07172,K18842 - - 0.00000000001947 73.0
PYH2_k127_3469249_0 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
PYH2_k127_3469249_1 Bacterial regulatory protein, Fis family K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 429.0
PYH2_k127_3469249_10 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000001115 86.0
PYH2_k127_3469249_11 TIGRFAM flagellar motor switch protein FliN K02417 - - 0.000000000000003178 79.0
PYH2_k127_3469249_12 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000005512 72.0
PYH2_k127_3469249_13 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000002264 66.0
PYH2_k127_3469249_14 Flagellar hook-length control protein FliK K02414 - - 0.0000004114 63.0
PYH2_k127_3469249_15 Flagellar FliJ protein - - - 0.0001502 50.0
PYH2_k127_3469249_2 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 372.0
PYH2_k127_3469249_3 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 316.0
PYH2_k127_3469249_4 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001512 278.0
PYH2_k127_3469249_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002106 239.0
PYH2_k127_3469249_6 flagellar basal-body rod protein FlgC K02388 - - 0.00000000000000000000000000000000000001817 149.0
PYH2_k127_3469249_7 diguanylate cyclase - - - 0.000000000000000000000000000000000009056 151.0
PYH2_k127_3469249_8 Flagellar assembly protein FliH K02411 - - 0.00000000000000000001779 101.0
PYH2_k127_3469249_9 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000002917 87.0
PYH2_k127_347262_0 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000217 129.0
PYH2_k127_347262_1 PFAM transposase IS66 K07484 - - 0.00000000000000000000000005119 119.0
PYH2_k127_347262_2 Winged helix-turn helix - - - 0.00000000000000006056 88.0
PYH2_k127_3488333_0 Involved in the tonB-independent uptake of proteins K03641 - - 9.8e-260 835.0
PYH2_k127_3488333_1 serine-type peptidase activity K06978,K21105 - 3.1.1.102 6.8e-231 736.0
PYH2_k127_3488333_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 438.0
PYH2_k127_3501976_0 Phospholipase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 348.0
PYH2_k127_3501976_1 ABC transporter, transmembrane K11085 - - 0.000000000000000000000000000000000000000000000000003542 188.0
PYH2_k127_3501976_2 energy transducer activity K02487,K03832,K06596 - - 0.000000000000000002321 94.0
PYH2_k127_3525167_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 555.0
PYH2_k127_3525167_1 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000004721 77.0
PYH2_k127_3546255_0 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 556.0
PYH2_k127_3546255_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 542.0
PYH2_k127_3546255_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 406.0
PYH2_k127_3546255_3 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 387.0
PYH2_k127_3561479_0 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 529.0
PYH2_k127_3561479_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 458.0
PYH2_k127_3561479_2 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 386.0
PYH2_k127_3561479_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 349.0
PYH2_k127_3561479_4 ABC transporter K02049 - - 0.0000000000000000000000000000000000001513 151.0
PYH2_k127_3561479_5 - - - - 0.0000000000000006859 87.0
PYH2_k127_3561479_6 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000001387 78.0
PYH2_k127_3574286_0 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000005477 168.0
PYH2_k127_3574286_1 Tetratricopeptide repeat - - - 0.000000000008651 78.0
PYH2_k127_3609577_0 asparaginase activity K01424,K05597 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1,3.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000654 248.0
PYH2_k127_3609577_1 PFAM regulatory protein TetR K16137 - - 0.00000000000000000000000000000000000000000000000000000001412 203.0
PYH2_k127_3609577_2 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000147 174.0
PYH2_k127_3629845_1 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 296.0
PYH2_k127_3629845_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000322 120.0
PYH2_k127_3675401_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.85e-214 674.0
PYH2_k127_3675401_1 Sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 505.0
PYH2_k127_3675401_2 mannose metabolic process - - - 0.000000000000000000000000000000000000000007905 172.0
PYH2_k127_3675401_3 Alpha-1,2-mannosidase - - - 0.00000000000000000000001939 115.0
PYH2_k127_3731058_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 431.0
PYH2_k127_3731058_1 Domain of unknown function (DUF5009) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 405.0
PYH2_k127_3731058_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 367.0
PYH2_k127_3731058_3 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 283.0
PYH2_k127_3731058_4 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000008301 230.0
PYH2_k127_3731058_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000004353 187.0
PYH2_k127_3731058_6 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000001382 94.0
PYH2_k127_3744237_0 Sortilin, neurotensin receptor 3, - - - 0.0 1196.0
PYH2_k127_3744237_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 334.0
PYH2_k127_3744237_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000006277 113.0
PYH2_k127_3744237_3 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000001125 66.0
PYH2_k127_3746916_0 Receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 541.0
PYH2_k127_3746916_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 473.0
PYH2_k127_3746916_10 ASPIC and UnbV - - - 0.00000000006166 65.0
PYH2_k127_3746916_11 PFAM cyclase dehydrase - - - 0.00001101 53.0
PYH2_k127_3746916_12 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00001771 57.0
PYH2_k127_3746916_13 DinB superfamily - - - 0.00003798 54.0
PYH2_k127_3746916_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.0005528 49.0
PYH2_k127_3746916_2 electron transport chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 385.0
PYH2_k127_3746916_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 364.0
PYH2_k127_3746916_4 reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000008768 240.0
PYH2_k127_3746916_5 pfam abc1 K03688 - - 0.0000000000000000000000000000000000000000000000000000000000002298 233.0
PYH2_k127_3746916_6 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000002339 199.0
PYH2_k127_3746916_7 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.0000000000000000000000000000000000008432 150.0
PYH2_k127_3746916_8 - - - - 0.000000000001598 75.0
PYH2_k127_3748517_0 Protein of unknown function (DUF1553) - - - 0.0 1134.0
PYH2_k127_3748517_1 Beta galactosidase small chain K01190 - 3.2.1.23 0.0 1113.0
PYH2_k127_3748517_10 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 368.0
PYH2_k127_3748517_11 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 304.0
PYH2_k127_3748517_12 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 294.0
PYH2_k127_3748517_13 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000002687 211.0
PYH2_k127_3748517_14 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000001972 203.0
PYH2_k127_3748517_15 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000001002 199.0
PYH2_k127_3748517_16 - - - - 0.0000000000000000000000000000000000000000000000000001056 205.0
PYH2_k127_3748517_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000745 184.0
PYH2_k127_3748517_19 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000001558 103.0
PYH2_k127_3748517_2 Natural resistance-associated macrophage protein K03322 - - 2.842e-255 802.0
PYH2_k127_3748517_20 methylamine metabolic process - - - 0.00000000000000000003402 96.0
PYH2_k127_3748517_3 Protein of unknown function (DUF1501) - - - 5.756e-243 758.0
PYH2_k127_3748517_4 Helicase conserved C-terminal domain K03580 - - 2.029e-208 672.0
PYH2_k127_3748517_5 Enterochelin esterase - - - 1.39e-202 644.0
PYH2_k127_3748517_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 543.0
PYH2_k127_3748517_7 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 517.0
PYH2_k127_3748517_8 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 381.0
PYH2_k127_3748517_9 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 385.0
PYH2_k127_3753389_0 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 292.0
PYH2_k127_3753389_1 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000003323 132.0
PYH2_k127_3753389_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000008366 118.0
PYH2_k127_3753389_3 - - - - 0.0000000000000000000000001511 119.0
PYH2_k127_3753389_4 Reprolysin (M12B) family zinc metalloprotease - - - 0.000000000000000000000007733 116.0
PYH2_k127_3753389_5 Putative collagen-binding domain of a collagenase - - - 0.00000000001187 66.0
PYH2_k127_3753389_6 Domain of unknown function (DUF4824) - - - 0.0000001536 63.0
PYH2_k127_3768245_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 291.0
PYH2_k127_3768245_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000006001 190.0
PYH2_k127_3768245_2 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog K01273 - 3.4.13.19 0.000000000000000000001417 95.0
PYH2_k127_3768245_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000718 69.0
PYH2_k127_378939_0 PFAM TonB-dependent Receptor - - - 7.216e-252 801.0
PYH2_k127_378939_1 COG1943 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000101 218.0
PYH2_k127_3812582_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003096 288.0
PYH2_k127_3812582_1 Ribonuclease E/G family K08301 - - 0.00007437 47.0
PYH2_k127_3817267_0 Alpha-1,2-mannosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 487.0
PYH2_k127_3817267_1 YoaP-like - - - 0.000000000000000000000000000000000000000000000000000000006869 212.0
PYH2_k127_3817267_3 - - - - 0.0000000000000000000000005619 113.0
PYH2_k127_3817267_4 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.0002535 53.0
PYH2_k127_3835600_0 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 597.0
PYH2_k127_3835600_1 Zinc-binding dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 546.0
PYH2_k127_3835600_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 443.0
PYH2_k127_3835600_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 376.0
PYH2_k127_3835600_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 371.0
PYH2_k127_3835600_5 amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 346.0
PYH2_k127_3835600_6 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000978 243.0
PYH2_k127_3835600_7 Lysin motif - - - 0.00000000000000000000000000000000000000009551 154.0
PYH2_k127_3835600_8 reductase K22185 - 1.1.1.175 0.000000000000000000000000000000000000002065 158.0
PYH2_k127_3835600_9 with SCP PR1 domains - - - 0.00000000379 66.0
PYH2_k127_3840028_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 2.451e-259 826.0
PYH2_k127_3840028_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 595.0
PYH2_k127_3840028_10 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 308.0
PYH2_k127_3840028_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 302.0
PYH2_k127_3840028_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 293.0
PYH2_k127_3840028_13 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004301 284.0
PYH2_k127_3840028_14 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000009383 271.0
PYH2_k127_3840028_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 266.0
PYH2_k127_3840028_16 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000003401 243.0
PYH2_k127_3840028_17 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000343 220.0
PYH2_k127_3840028_18 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000001423 188.0
PYH2_k127_3840028_19 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000008292 191.0
PYH2_k127_3840028_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 591.0
PYH2_k127_3840028_20 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000009758 183.0
PYH2_k127_3840028_21 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000007797 174.0
PYH2_k127_3840028_22 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000000000000000000000000000000000000368 165.0
PYH2_k127_3840028_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000002785 138.0
PYH2_k127_3840028_24 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000687 128.0
PYH2_k127_3840028_25 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000005516 126.0
PYH2_k127_3840028_26 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000001192 119.0
PYH2_k127_3840028_27 - - - - 0.00000000000000000002127 100.0
PYH2_k127_3840028_28 Bacterial regulatory proteins, crp family K10914 - - 0.00000001171 61.0
PYH2_k127_3840028_29 TonB C terminal K03832 - - 0.00000005568 64.0
PYH2_k127_3840028_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 550.0
PYH2_k127_3840028_30 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00009875 53.0
PYH2_k127_3840028_4 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 543.0
PYH2_k127_3840028_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 498.0
PYH2_k127_3840028_6 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 430.0
PYH2_k127_3840028_7 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 358.0
PYH2_k127_3840028_8 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 322.0
PYH2_k127_3840028_9 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 332.0
PYH2_k127_3843815_0 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1319.0
PYH2_k127_3843815_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 3.013e-215 681.0
PYH2_k127_3843815_10 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 389.0
PYH2_k127_3843815_11 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 359.0
PYH2_k127_3843815_12 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 334.0
PYH2_k127_3843815_13 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 335.0
PYH2_k127_3843815_14 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 319.0
PYH2_k127_3843815_15 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 303.0
PYH2_k127_3843815_16 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 322.0
PYH2_k127_3843815_17 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 306.0
PYH2_k127_3843815_18 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007461 291.0
PYH2_k127_3843815_19 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005685 278.0
PYH2_k127_3843815_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 627.0
PYH2_k127_3843815_20 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 274.0
PYH2_k127_3843815_21 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 269.0
PYH2_k127_3843815_22 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000159 267.0
PYH2_k127_3843815_23 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001182 276.0
PYH2_k127_3843815_24 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 263.0
PYH2_k127_3843815_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001388 238.0
PYH2_k127_3843815_26 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000003896 252.0
PYH2_k127_3843815_27 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000002871 230.0
PYH2_k127_3843815_28 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000008081 223.0
PYH2_k127_3843815_29 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000006787 217.0
PYH2_k127_3843815_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 557.0
PYH2_k127_3843815_30 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000003482 211.0
PYH2_k127_3843815_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000009552 182.0
PYH2_k127_3843815_32 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000002298 186.0
PYH2_k127_3843815_33 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000009006 182.0
PYH2_k127_3843815_34 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000001103 178.0
PYH2_k127_3843815_35 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000288 177.0
PYH2_k127_3843815_36 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000004888 174.0
PYH2_k127_3843815_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000006366 159.0
PYH2_k127_3843815_38 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000002808 156.0
PYH2_k127_3843815_39 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000002363 150.0
PYH2_k127_3843815_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 471.0
PYH2_k127_3843815_40 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000004536 141.0
PYH2_k127_3843815_41 Helix-turn-helix domain - - - 0.00000000000000000000000000000000002972 141.0
PYH2_k127_3843815_42 HlyD family secretion protein - - - 0.0000000000000000000000000000000001217 151.0
PYH2_k127_3843815_43 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000001222 146.0
PYH2_k127_3843815_44 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000002824 135.0
PYH2_k127_3843815_45 Smr domain - - - 0.000000000000000000000000000000001516 139.0
PYH2_k127_3843815_46 Belongs to the HesB IscA family - - - 0.0000000000000000000000000000004847 125.0
PYH2_k127_3843815_47 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000001309 117.0
PYH2_k127_3843815_48 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000003365 107.0
PYH2_k127_3843815_49 - - - - 0.000000000000000000008722 100.0
PYH2_k127_3843815_5 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 462.0
PYH2_k127_3843815_50 - - - - 0.00000000000000000006223 93.0
PYH2_k127_3843815_51 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000002103 93.0
PYH2_k127_3843815_52 HlyD family secretion protein - - - 0.00000000000000001368 96.0
PYH2_k127_3843815_53 regulatory protein K11923,K13638 - - 0.00000000000000001447 89.0
PYH2_k127_3843815_54 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000001278 78.0
PYH2_k127_3843815_56 Major Facilitator Superfamily - - - 0.00000000005813 75.0
PYH2_k127_3843815_57 Putative adhesin - - - 0.00000000007384 72.0
PYH2_k127_3843815_58 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000001097 71.0
PYH2_k127_3843815_59 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.000000004499 61.0
PYH2_k127_3843815_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 450.0
PYH2_k127_3843815_60 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000002482 61.0
PYH2_k127_3843815_61 TIGRFAM TonB family protein K03832 - - 0.0000008438 60.0
PYH2_k127_3843815_62 - - - - 0.00007506 50.0
PYH2_k127_3843815_63 Uncharacterized conserved protein (DUF2203) - - - 0.0003874 48.0
PYH2_k127_3843815_64 haloacid dehalogenase K01091 - 3.1.3.18 0.0009976 49.0
PYH2_k127_3843815_7 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 400.0
PYH2_k127_3843815_8 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 381.0
PYH2_k127_3843815_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 373.0
PYH2_k127_3846258_0 phosphorelay signal transduction system K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
PYH2_k127_3846258_1 Histidine kinase - - - 0.0000000000000000000000000000000000001615 146.0
PYH2_k127_3848239_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1185.0
PYH2_k127_3848239_1 Phosphoesterase family - - - 3.695e-254 811.0
PYH2_k127_3848239_2 Peptidase M14, carboxypeptidase A - - - 5.341e-251 801.0
PYH2_k127_3848239_3 Peptidase family M49 K01277 - 3.4.14.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 565.0
PYH2_k127_3848239_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000589 187.0
PYH2_k127_3848239_5 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000007729 190.0
PYH2_k127_3848239_6 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000004749 154.0
PYH2_k127_3848239_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000002006 85.0
PYH2_k127_3848239_8 Anti-sigma-K factor RskA - - - 0.000000002522 69.0
PYH2_k127_3855917_0 unsaturated chondroitin disaccharide hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 475.0
PYH2_k127_3855917_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 435.0
PYH2_k127_3855917_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 312.0
PYH2_k127_3855917_3 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000002608 175.0
PYH2_k127_3862612_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1992.0
PYH2_k127_3862612_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1816.0
PYH2_k127_3862612_10 response regulator, receiver K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 410.0
PYH2_k127_3862612_11 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 395.0
PYH2_k127_3862612_12 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 396.0
PYH2_k127_3862612_13 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 366.0
PYH2_k127_3862612_14 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 359.0
PYH2_k127_3862612_15 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 327.0
PYH2_k127_3862612_16 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 311.0
PYH2_k127_3862612_17 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 297.0
PYH2_k127_3862612_18 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 306.0
PYH2_k127_3862612_19 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 311.0
PYH2_k127_3862612_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 9.782e-211 669.0
PYH2_k127_3862612_20 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008741 302.0
PYH2_k127_3862612_21 Lipid-A-disaccharide synthetase K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000005017 273.0
PYH2_k127_3862612_22 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000001426 268.0
PYH2_k127_3862612_23 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000001175 236.0
PYH2_k127_3862612_24 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000008027 231.0
PYH2_k127_3862612_25 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
PYH2_k127_3862612_26 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000002427 203.0
PYH2_k127_3862612_27 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000008018 185.0
PYH2_k127_3862612_28 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000007306 199.0
PYH2_k127_3862612_29 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000003933 179.0
PYH2_k127_3862612_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.907e-201 643.0
PYH2_k127_3862612_30 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000239 162.0
PYH2_k127_3862612_31 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000002171 153.0
PYH2_k127_3862612_32 transcriptional regulator K21900 - - 0.000000000000000000000000000000000000001146 158.0
PYH2_k127_3862612_33 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000001773 159.0
PYH2_k127_3862612_34 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000008071 140.0
PYH2_k127_3862612_35 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000003627 138.0
PYH2_k127_3862612_36 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.000000000000000000000000000000008072 136.0
PYH2_k127_3862612_37 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000001359 132.0
PYH2_k127_3862612_38 nucleotide metabolic process - - - 0.0000000000000000000000000000009818 131.0
PYH2_k127_3862612_39 Methyltransferase domain - - - 0.00000000000000000000000000003496 130.0
PYH2_k127_3862612_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 535.0
PYH2_k127_3862612_40 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000009969 124.0
PYH2_k127_3862612_41 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000001263 119.0
PYH2_k127_3862612_42 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000002459 112.0
PYH2_k127_3862612_43 6-phosphogluconolactonase activity - - - 0.0000000000000000000002357 114.0
PYH2_k127_3862612_44 Trm112p-like protein K09791 - - 0.0000000000000000000007851 95.0
PYH2_k127_3862612_45 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000005763 89.0
PYH2_k127_3862612_46 structural constituent of ribosome K02913 - - 0.0000000000000003054 79.0
PYH2_k127_3862612_47 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000001389 79.0
PYH2_k127_3862612_48 - - - - 0.000000000000147 82.0
PYH2_k127_3862612_49 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000002624 69.0
PYH2_k127_3862612_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 452.0
PYH2_k127_3862612_50 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000007371 75.0
PYH2_k127_3862612_51 Pfam:N_methyl_2 - - - 0.00000000001318 74.0
PYH2_k127_3862612_52 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000015 67.0
PYH2_k127_3862612_53 Domain of unknown function DUF87 - - - 0.00000001596 65.0
PYH2_k127_3862612_54 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000005619 53.0
PYH2_k127_3862612_55 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000138 49.0
PYH2_k127_3862612_6 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 434.0
PYH2_k127_3862612_7 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 422.0
PYH2_k127_3862612_8 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 415.0
PYH2_k127_3862612_9 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 412.0
PYH2_k127_3887658_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.011e-237 749.0
PYH2_k127_3887658_1 ABC 3 transport family K02075,K09816 - - 0.00000000000000000000000167 114.0
PYH2_k127_3887658_2 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000003912 66.0
PYH2_k127_3888174_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 376.0
PYH2_k127_3914011_0 Single Cache domain 2 K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000146 279.0
PYH2_k127_3914011_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000004179 108.0
PYH2_k127_3914011_2 - - - - 0.000000000000000000000004445 106.0
PYH2_k127_3914011_3 PFAM Transglycosylase associated protein - - - 0.00000000000000000006258 92.0
PYH2_k127_3923053_0 Peptidase S46 - - - 2.743e-252 805.0
PYH2_k127_3923053_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 467.0
PYH2_k127_3923053_10 - - - - 0.000000000000000000000000000000116 134.0
PYH2_k127_3923053_11 YjbR - - - 0.00000000000000000000000000000202 124.0
PYH2_k127_3923053_12 Methane oxygenase PmoA - - - 0.000000000000000465 89.0
PYH2_k127_3923053_14 - - - - 0.00000000003571 76.0
PYH2_k127_3923053_2 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 447.0
PYH2_k127_3923053_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 415.0
PYH2_k127_3923053_4 Major Facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006481 256.0
PYH2_k127_3923053_5 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000009646 251.0
PYH2_k127_3923053_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000006233 231.0
PYH2_k127_3923053_7 PFAM D5 N terminal like K06919 - - 0.0000000000000000000000000000000000000000000000000000000000002193 241.0
PYH2_k127_3923053_8 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000006248 218.0
PYH2_k127_3923053_9 - - - - 0.0000000000000000000000000000000000000002876 161.0
PYH2_k127_3925363_0 Peptidase M14, carboxypeptidase A - - - 0.0 1371.0
PYH2_k127_3925363_1 cellulose binding - - - 0.0 1142.0
PYH2_k127_3925363_10 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
PYH2_k127_3925363_11 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 446.0
PYH2_k127_3925363_12 Peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 447.0
PYH2_k127_3925363_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 428.0
PYH2_k127_3925363_14 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 409.0
PYH2_k127_3925363_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 407.0
PYH2_k127_3925363_16 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 392.0
PYH2_k127_3925363_17 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 378.0
PYH2_k127_3925363_18 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 369.0
PYH2_k127_3925363_19 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 370.0
PYH2_k127_3925363_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.332e-309 987.0
PYH2_k127_3925363_20 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 362.0
PYH2_k127_3925363_21 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 349.0
PYH2_k127_3925363_22 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 342.0
PYH2_k127_3925363_23 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 330.0
PYH2_k127_3925363_24 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 316.0
PYH2_k127_3925363_25 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 306.0
PYH2_k127_3925363_26 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 313.0
PYH2_k127_3925363_27 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 290.0
PYH2_k127_3925363_28 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000173 286.0
PYH2_k127_3925363_29 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002684 264.0
PYH2_k127_3925363_3 Uncharacterized protein family (UPF0051) K09014 - - 4.781e-266 827.0
PYH2_k127_3925363_30 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
PYH2_k127_3925363_31 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000006162 228.0
PYH2_k127_3925363_32 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 - - 0.00000000000000000000000000000000000000000000000000000000001915 225.0
PYH2_k127_3925363_33 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000003997 211.0
PYH2_k127_3925363_34 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000000000762 192.0
PYH2_k127_3925363_35 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000001085 196.0
PYH2_k127_3925363_36 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000001105 188.0
PYH2_k127_3925363_37 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000001689 184.0
PYH2_k127_3925363_38 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000006479 184.0
PYH2_k127_3925363_39 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.00000000000000000000000000000000000000000000001092 183.0
PYH2_k127_3925363_4 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence - - - 2.272e-220 695.0
PYH2_k127_3925363_40 L-rhamnose mutarotase K03534 - 5.1.3.32 0.000000000000000000000000000000000000000000003279 166.0
PYH2_k127_3925363_41 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000004227 169.0
PYH2_k127_3925363_42 2 iron, 2 sulfur cluster binding - - - 0.0000000000000000000000000000000000000005434 153.0
PYH2_k127_3925363_43 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000001256 162.0
PYH2_k127_3925363_44 PaaD-like protein - - - 0.000000000000000000000000000000000000005102 148.0
PYH2_k127_3925363_45 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000331 149.0
PYH2_k127_3925363_46 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000006352 134.0
PYH2_k127_3925363_47 Met-10+ like-protein - - - 0.00000000000000000000000000005572 124.0
PYH2_k127_3925363_48 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000001123 113.0
PYH2_k127_3925363_49 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 - - 0.0000000000000000000000177 104.0
PYH2_k127_3925363_5 PFAM Cytochrome c assembly protein K02198 - - 3.361e-217 693.0
PYH2_k127_3925363_50 DinB superfamily - - - 0.00000000000000000002609 100.0
PYH2_k127_3925363_51 PAP2 superfamily - - - 0.00000000000000000007487 100.0
PYH2_k127_3925363_52 - - - - 0.000000000000008693 87.0
PYH2_k127_3925363_53 mttA/Hcf106 family K03116 - - 0.00000000000004554 74.0
PYH2_k127_3925363_54 Penicillinase repressor - - - 0.00000000003378 70.0
PYH2_k127_3925363_55 subunit of a heme lyase K02200 - - 0.00000000006415 70.0
PYH2_k127_3925363_56 - - - - 0.000000002486 64.0
PYH2_k127_3925363_57 Flagellar protein YcgR - - - 0.00000001979 65.0
PYH2_k127_3925363_6 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 3.731e-212 677.0
PYH2_k127_3925363_7 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 8.078e-210 663.0
PYH2_k127_3925363_8 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 601.0
PYH2_k127_3925363_9 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 597.0
PYH2_k127_3934852_0 mannose metabolic process - - - 3.245e-250 793.0
PYH2_k127_3937651_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 432.0
PYH2_k127_3937651_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000003963 97.0
PYH2_k127_3937651_2 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000005493 93.0
PYH2_k127_3937651_3 Integrin alpha (beta-propellor repeats). - - - 0.00000008835 65.0
PYH2_k127_3937651_4 Putative zinc-finger - - - 0.0003824 50.0
PYH2_k127_3956988_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1006.0
PYH2_k127_3956988_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003411 234.0
PYH2_k127_3956988_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000002832 199.0
PYH2_k127_3956988_3 translation elongation factor activity K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000002456 81.0
PYH2_k127_3957969_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000184 167.0
PYH2_k127_3957969_1 zinc ion binding - - - 0.000000000000000000000003896 104.0
PYH2_k127_3957969_2 - - - - 0.0000000002006 66.0
PYH2_k127_396142_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 513.0
PYH2_k127_396142_1 O-GlcNAcase BT_4395 K01197 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 3.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 406.0
PYH2_k127_396142_10 - - - - 0.0000000000000000006792 97.0
PYH2_k127_396142_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000003357 79.0
PYH2_k127_396142_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 318.0
PYH2_k127_396142_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009013 281.0
PYH2_k127_396142_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005586 277.0
PYH2_k127_396142_5 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000001606 249.0
PYH2_k127_396142_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000003274 158.0
PYH2_k127_396142_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000005032 138.0
PYH2_k127_396142_8 Surface antigen - - - 0.000000000000000000000000004004 123.0
PYH2_k127_396142_9 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.0000000000000000001255 100.0
PYH2_k127_3967043_0 Protein kinase domain K12132 - 2.7.11.1 3.318e-263 842.0
PYH2_k127_3967043_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 608.0
PYH2_k127_3967043_2 RNA recognition motif - - - 0.00000000000000000009988 95.0
PYH2_k127_3967043_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0008562 43.0
PYH2_k127_3969029_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 561.0
PYH2_k127_3969029_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 523.0
PYH2_k127_3969029_2 Urocanase C-terminal domain K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 451.0
PYH2_k127_3969029_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 339.0
PYH2_k127_3969029_4 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 293.0
PYH2_k127_3969029_5 PFAM ABC transporter related K02028,K10041,K17076 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004267 280.0
PYH2_k127_3969029_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004231 254.0
PYH2_k127_3969029_7 PFAM Peptidase M48 - - - 0.000000000000000000000000000000000003988 158.0
PYH2_k127_3969029_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000002237 119.0
PYH2_k127_3970074_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1038.0
PYH2_k127_3970074_1 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 6.087e-280 874.0
PYH2_k127_3970074_10 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000002006 87.0
PYH2_k127_3970074_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 599.0
PYH2_k127_3970074_3 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 514.0
PYH2_k127_3970074_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001728 279.0
PYH2_k127_3970074_5 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000002763 263.0
PYH2_k127_3970074_6 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000134 152.0
PYH2_k127_3970074_7 PFAM Heat shock protein Hsp20 K13993 - - 0.00000000000000000000000000000000001359 140.0
PYH2_k127_3970074_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000006647 134.0
PYH2_k127_3970074_9 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000002477 119.0
PYH2_k127_3985483_0 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 394.0
PYH2_k127_3985483_1 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 383.0
PYH2_k127_3985483_2 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 363.0
PYH2_k127_3985483_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 268.0
PYH2_k127_3985483_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001785 276.0
PYH2_k127_3985483_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002874 250.0
PYH2_k127_3985483_6 Two component transcriptional regulator, winged helix family K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000001523 233.0
PYH2_k127_3985483_7 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000003145 173.0
PYH2_k127_3996649_0 belongs to the aldehyde dehydrogenase family K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 488.0
PYH2_k127_3996649_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 434.0
PYH2_k127_3996649_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000001863 224.0
PYH2_k127_3996649_11 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000004881 222.0
PYH2_k127_3996649_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000935 213.0
PYH2_k127_3996649_13 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000002841 192.0
PYH2_k127_3996649_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000001498 175.0
PYH2_k127_3996649_15 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000005003 182.0
PYH2_k127_3996649_16 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000004584 166.0
PYH2_k127_3996649_17 PFAM microcompartments protein K04027 - - 0.000000000000000000000000000000000000002895 148.0
PYH2_k127_3996649_18 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000001268 120.0
PYH2_k127_3996649_19 Domain of unknown function (DUF4115) - - - 0.00000000000000000000000001333 120.0
PYH2_k127_3996649_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 389.0
PYH2_k127_3996649_20 - - - - 0.000000000000000000000007012 114.0
PYH2_k127_3996649_21 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000002687 105.0
PYH2_k127_3996649_22 PFAM SNARE associated Golgi protein - - - 0.00000000000001303 83.0
PYH2_k127_3996649_23 outer membrane lipoprotein carrier protein LolA - - - 0.0004502 50.0
PYH2_k127_3996649_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 375.0
PYH2_k127_3996649_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 298.0
PYH2_k127_3996649_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006893 290.0
PYH2_k127_3996649_6 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001294 276.0
PYH2_k127_3996649_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002272 257.0
PYH2_k127_3996649_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000003832 238.0
PYH2_k127_3996649_9 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000001264 246.0
PYH2_k127_4010984_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 495.0
PYH2_k127_4010984_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000258 252.0
PYH2_k127_4010984_2 hydrogenase maturation protease K03605 - - 0.0000000000000000001244 102.0
PYH2_k127_4010984_3 - - - - 0.00000000000003979 81.0
PYH2_k127_4015119_0 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000011 164.0
PYH2_k127_4015119_1 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000002998 164.0
PYH2_k127_4015119_2 Lipocalin-like domain - - - 0.00000000000000000000000000018 122.0
PYH2_k127_4015119_3 amidohydrolase K01845 - 5.4.3.8 0.000000000000000000000001221 117.0
PYH2_k127_403107_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 522.0
PYH2_k127_403107_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 470.0
PYH2_k127_403107_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000008506 200.0
PYH2_k127_4038117_0 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000001231 237.0
PYH2_k127_4038117_1 - - - - 0.00009277 45.0
PYH2_k127_4040599_0 Type II transport protein GspH K08084 - - 0.000004944 56.0
PYH2_k127_4040599_1 Pilus assembly protein PilX - - - 0.0003851 45.0
PYH2_k127_4040599_2 pilus assembly protein PilW K02672 - - 0.0007971 51.0
PYH2_k127_4066261_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001986 283.0
PYH2_k127_4066261_1 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000236 194.0
PYH2_k127_4066261_2 phosphorelay signal transduction system K14987 - - 0.000000000000000000000000059 113.0
PYH2_k127_4066261_3 PIN domain - - - 0.000000000000000000000005857 104.0
PYH2_k127_4066261_4 - - - - 0.0000000000003615 72.0
PYH2_k127_4066261_5 Two component transcriptional regulator, LuxR family - - - 0.0000000002999 63.0
PYH2_k127_4083752_0 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 314.0
PYH2_k127_4083752_1 Integrase - - - 0.000000000000000000000000000000000000001201 151.0
PYH2_k127_4113227_0 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 296.0
PYH2_k127_4113227_1 transport - - - 0.000000000000000000000000000000000000000000000000000000213 201.0
PYH2_k127_4113227_2 PFAM oxidoreductase domain protein - - - 0.00000000000000002874 87.0
PYH2_k127_4144064_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 311.0
PYH2_k127_4157205_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 348.0
PYH2_k127_4157205_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
PYH2_k127_4157205_2 - - - - 0.000000000000000000000000000000000000000000000000000522 191.0
PYH2_k127_4157205_3 DinB superfamily - - - 0.000000000000000000000000000000000000000001375 161.0
PYH2_k127_4157205_4 chlorophyll binding - - - 0.0000000000000000000000000000000001404 150.0
PYH2_k127_4157205_5 Tellurite resistance protein TehB - - - 0.0000000000000000000000004508 115.0
PYH2_k127_4157205_6 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000004874 89.0
PYH2_k127_4157205_7 PFAM Amidohydrolase 2 - - - 0.0000000000007331 80.0
PYH2_k127_4162388_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000151 259.0
PYH2_k127_4162388_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000005695 239.0
PYH2_k127_4162388_2 ATP-independent chaperone mediated protein folding K02005 - - 0.000002998 58.0
PYH2_k127_4162388_3 - - - - 0.0004827 43.0
PYH2_k127_4167655_0 iron-nicotianamine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 386.0
PYH2_k127_423188_0 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000004526 173.0
PYH2_k127_423188_1 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.0000000001685 66.0
PYH2_k127_4259064_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000001214 241.0
PYH2_k127_4259064_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000832 138.0
PYH2_k127_4259064_2 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.00000000000000000003138 96.0
PYH2_k127_4259064_3 Integrase core domain - - - 0.0000000294 56.0
PYH2_k127_4278138_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 523.0
PYH2_k127_4278138_1 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 498.0
PYH2_k127_4278138_2 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000007888 187.0
PYH2_k127_4278138_3 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000002086 154.0
PYH2_k127_4278138_4 gluconolactonase K01053 - 3.1.1.17 0.00000002972 57.0
PYH2_k127_4315955_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 534.0
PYH2_k127_4315955_1 Alpha-L-fucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 399.0
PYH2_k127_4315955_2 transporter K02429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 325.0
PYH2_k127_4315955_3 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 332.0
PYH2_k127_4315955_4 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 314.0
PYH2_k127_4315955_5 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 0.00000000000000000000000000000000000000003402 170.0
PYH2_k127_4315955_6 Protein of unknown function (DUF2961) - - - 0.00000000000002143 80.0
PYH2_k127_4375314_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1154.0
PYH2_k127_4375314_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1021.0
PYH2_k127_4375314_10 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 332.0
PYH2_k127_4375314_11 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 327.0
PYH2_k127_4375314_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 319.0
PYH2_k127_4375314_13 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 284.0
PYH2_k127_4375314_14 glycerol channel activity K09876,K09877,K09886,K10404 GO:0002376,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006833,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008643,GO:0009605,GO:0009607,GO:0009617,GO:0015250,GO:0015267,GO:0015318,GO:0015791,GO:0015793,GO:0015850,GO:0016020,GO:0016323,GO:0022803,GO:0022838,GO:0022857,GO:0042044,GO:0042742,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0045087,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071702,GO:0071944,GO:0098542,GO:0098590 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002236 283.0
PYH2_k127_4375314_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001719 257.0
PYH2_k127_4375314_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008965 264.0
PYH2_k127_4375314_17 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000001089 229.0
PYH2_k127_4375314_18 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000003404 166.0
PYH2_k127_4375314_19 integral membrane protein - - - 0.000000000000000000000000000000000000009505 154.0
PYH2_k127_4375314_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.271e-296 919.0
PYH2_k127_4375314_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000005254 136.0
PYH2_k127_4375314_21 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000002514 127.0
PYH2_k127_4375314_22 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000001658 116.0
PYH2_k127_4375314_23 COG0006 Xaa-Pro aminopeptidase - - - 0.0000000000000000000009396 109.0
PYH2_k127_4375314_24 Glycosyltransferase like family 2 - - - 0.00000000000000000004723 106.0
PYH2_k127_4375314_25 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000008591 93.0
PYH2_k127_4375314_26 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000004481 86.0
PYH2_k127_4375314_27 nuclear chromosome segregation - - - 0.000000000001175 81.0
PYH2_k127_4375314_28 Tetratricopeptide repeat - - - 0.00000000004976 74.0
PYH2_k127_4375314_29 AhpC/TSA antioxidant enzyme - - - 0.000000005577 63.0
PYH2_k127_4375314_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.847e-291 914.0
PYH2_k127_4375314_30 PFAM Methyltransferase type 11 - - - 0.000004699 58.0
PYH2_k127_4375314_4 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 2.525e-267 848.0
PYH2_k127_4375314_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 8.007e-239 744.0
PYH2_k127_4375314_6 aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 513.0
PYH2_k127_4375314_7 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 462.0
PYH2_k127_4375314_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 424.0
PYH2_k127_4375314_9 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 387.0
PYH2_k127_440430_0 Domain of unknown function (DUF4277) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 333.0
PYH2_k127_440430_1 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001346 278.0
PYH2_k127_440430_2 KDPG and KHG aldolase - - - 0.000008954 52.0
PYH2_k127_4411996_0 Receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 431.0
PYH2_k127_453080_0 serine-type peptidase activity K08676 - - 0.0 1121.0
PYH2_k127_453080_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 369.0
PYH2_k127_453080_2 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 327.0
PYH2_k127_453080_3 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007216 265.0
PYH2_k127_453080_4 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000002417 125.0
PYH2_k127_453080_5 - - - - 0.00000000000000000000000009287 113.0
PYH2_k127_453080_6 protein transport - - - 0.00000000000000001128 86.0
PYH2_k127_453080_7 von Willebrand factor, type A K07114 - - 0.0000000000005416 81.0
PYH2_k127_453080_8 transport - - - 0.0000002589 60.0
PYH2_k127_4548580_0 PFAM transposase IS66 K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 326.0
PYH2_k127_4548580_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 296.0
PYH2_k127_4548580_2 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000000000004418 133.0
PYH2_k127_4548580_3 GTP binding - - - 0.0000008305 54.0
PYH2_k127_4592812_0 PFAM Uncharacterised BCR, COG1649 - - - 6.966e-225 704.0
PYH2_k127_464805_0 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 2.762e-214 678.0
PYH2_k127_464805_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 314.0
PYH2_k127_464805_2 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 314.0
PYH2_k127_464805_3 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 270.0
PYH2_k127_464805_5 amidohydrolase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000003433 166.0
PYH2_k127_4675206_0 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 486.0
PYH2_k127_4675206_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 457.0
PYH2_k127_4675206_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 326.0
PYH2_k127_4675206_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 323.0
PYH2_k127_4675206_4 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 322.0
PYH2_k127_4675206_5 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000005606 181.0
PYH2_k127_4675206_6 ECF sigma factor K03088 - - 0.000000000000000000000005762 111.0
PYH2_k127_4675206_7 peptide catabolic process - - - 0.00000000000000000004249 106.0
PYH2_k127_4675206_8 Heavy-metal resistance - - - 0.0000000001836 68.0
PYH2_k127_4693103_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.543e-205 648.0
PYH2_k127_4693103_1 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 391.0
PYH2_k127_4693103_2 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000003119 66.0
PYH2_k127_4693103_3 Tetratricopeptide repeat - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0031505,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045229,GO:0071554,GO:0071555,GO:0071840,GO:0071852 - 0.000003312 59.0
PYH2_k127_4705804_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.825e-252 785.0
PYH2_k127_4705804_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 587.0
PYH2_k127_4705804_10 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000101 218.0
PYH2_k127_4705804_11 Fibronectin type 3 domain K06882 - - 0.0000000000000000000000000000000001494 147.0
PYH2_k127_4705804_12 Histidine kinase - - - 0.000000000000000000000000000000001466 134.0
PYH2_k127_4705804_13 HD domain - - - 0.0000000000000000000001171 106.0
PYH2_k127_4705804_14 Biotin-requiring enzyme - - - 0.0000000000000000000004378 103.0
PYH2_k127_4705804_15 Tetratricopeptide repeat - - - 0.000001748 60.0
PYH2_k127_4705804_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 586.0
PYH2_k127_4705804_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 584.0
PYH2_k127_4705804_4 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 466.0
PYH2_k127_4705804_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 325.0
PYH2_k127_4705804_6 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 316.0
PYH2_k127_4705804_7 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 316.0
PYH2_k127_4705804_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002835 266.0
PYH2_k127_4705804_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
PYH2_k127_4722313_0 serine-type peptidase activity K01278 - 3.4.14.5 2.946e-316 985.0
PYH2_k127_4722313_1 dipeptidase activity - - - 1.977e-221 700.0
PYH2_k127_4722313_10 Domain of unknown function (DUF4832) - - - 0.00000000000000000000000000000001924 128.0
PYH2_k127_4722313_11 - - - - 0.000000005922 64.0
PYH2_k127_4722313_12 PAN domain - - - 0.0000008227 55.0
PYH2_k127_4722313_13 - - - - 0.0004815 49.0
PYH2_k127_4722313_2 succinylglutamate desuccinylase aspartoacylase K06987,K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 542.0
PYH2_k127_4722313_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 515.0
PYH2_k127_4722313_4 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 444.0
PYH2_k127_4722313_5 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
PYH2_k127_4722313_6 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002991 233.0
PYH2_k127_4722313_7 - - - - 0.0000000000000000000000000000000000000000000000000000005774 199.0
PYH2_k127_4722313_8 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000006243 199.0
PYH2_k127_4722313_9 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000004342 175.0
PYH2_k127_4743481_0 Belongs to the glycosyl hydrolase 32 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 452.0
PYH2_k127_4743481_1 F5 8 type C domain protein K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 419.0
PYH2_k127_4743481_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
PYH2_k127_4748159_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.411e-251 796.0
PYH2_k127_4748159_1 Peptidase family M28 - - - 4.694e-209 665.0
PYH2_k127_4748159_11 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000007157 184.0
PYH2_k127_4748159_12 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000001528 175.0
PYH2_k127_4748159_13 - - - - 0.0000000000000000000000000000000000000001968 158.0
PYH2_k127_4748159_14 Glycosyl hydrolase family 92 - - - 0.0000000000000000000000000000000001491 151.0
PYH2_k127_4748159_15 Sigma-70 region 2 K03088 - - 0.0000000000000000000003225 102.0
PYH2_k127_4748159_16 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000003879 77.0
PYH2_k127_4748159_17 Calcineurin-like phosphoesterase superfamily domain K01077 - 3.1.3.1 0.00000000001297 77.0
PYH2_k127_4748159_19 Transposase - - - 0.00002812 46.0
PYH2_k127_4748159_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 409.0
PYH2_k127_4748159_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 392.0
PYH2_k127_4748159_4 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 398.0
PYH2_k127_4748159_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 370.0
PYH2_k127_4748159_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 365.0
PYH2_k127_4748159_7 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002652 276.0
PYH2_k127_4748159_8 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001343 224.0
PYH2_k127_4748159_9 - - - - 0.00000000000000000000000000000000000000000000000000000000005913 225.0
PYH2_k127_4748332_0 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008621 261.0
PYH2_k127_4748332_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000001339 154.0
PYH2_k127_4748332_2 ribosomal protein - - - 0.000001671 55.0
PYH2_k127_4762831_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000004115 238.0
PYH2_k127_4762831_1 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000001357 220.0
PYH2_k127_4762831_2 phosphate-selective porin O and P - - - 0.0000000000000000004542 101.0
PYH2_k127_4777683_0 glycoside hydrolase family 2 sugar binding - - - 9.567e-293 928.0
PYH2_k127_4777683_1 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 608.0
PYH2_k127_4777683_10 Fibronectin type III-like domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000002261 197.0
PYH2_k127_4777683_11 HD domain K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000002593 203.0
PYH2_k127_4777683_12 Hydrolase - - - 0.000000000000000000000000000000000000005671 159.0
PYH2_k127_4777683_13 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.0000000000000000003247 93.0
PYH2_k127_4777683_2 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 577.0
PYH2_k127_4777683_3 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 574.0
PYH2_k127_4777683_4 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 573.0
PYH2_k127_4777683_5 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 397.0
PYH2_k127_4777683_6 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 421.0
PYH2_k127_4777683_7 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 386.0
PYH2_k127_4777683_9 RbsD / FucU transport protein family K02431 - 5.1.3.29 0.000000000000000000000000000000000000000000000000000000000000009473 219.0
PYH2_k127_4777840_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 293.0
PYH2_k127_4777840_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000005425 175.0
PYH2_k127_4777840_2 Cytochrome c554 and c-prime - - - 0.00000000000000000002272 101.0
PYH2_k127_4794299_0 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 397.0
PYH2_k127_4794299_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
PYH2_k127_4794299_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000001123 212.0
PYH2_k127_479485_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1084.0
PYH2_k127_479485_1 Glycosyl hydrolases family 38 N-terminal domain - - - 1.148e-231 760.0
PYH2_k127_479485_10 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 362.0
PYH2_k127_479485_11 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 370.0
PYH2_k127_479485_12 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
PYH2_k127_479485_13 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
PYH2_k127_479485_14 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005062 281.0
PYH2_k127_479485_15 xaa-pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004029 261.0
PYH2_k127_479485_16 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000002031 243.0
PYH2_k127_479485_17 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000009315 226.0
PYH2_k127_479485_18 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000002551 206.0
PYH2_k127_479485_19 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000006263 199.0
PYH2_k127_479485_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.498e-216 681.0
PYH2_k127_479485_20 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000006276 194.0
PYH2_k127_479485_21 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000004665 195.0
PYH2_k127_479485_22 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000001124 176.0
PYH2_k127_479485_23 Peptidase family M23 - - - 0.000000000000000000000000000000000000000001404 168.0
PYH2_k127_479485_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002637 132.0
PYH2_k127_479485_25 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000006769 131.0
PYH2_k127_479485_26 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000001479 114.0
PYH2_k127_479485_27 PFAM Fimbrial assembly K02461 - - 0.00000000000000000000482 107.0
PYH2_k127_479485_28 pilus assembly protein PilW K02459 - - 0.0000000000004036 81.0
PYH2_k127_479485_29 phosphorylase K01243 - 3.2.2.9 0.000000000002393 77.0
PYH2_k127_479485_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 6.568e-211 669.0
PYH2_k127_479485_30 Protein of unknown function (DUF2905) - - - 0.0000000001328 64.0
PYH2_k127_479485_31 BFD-like [2Fe-2S] binding domain K00360 - - 0.000000001039 63.0
PYH2_k127_479485_32 Prokaryotic N-terminal methylation motif - - - 0.000000006821 64.0
PYH2_k127_479485_33 Type II secretion system (T2SS), protein M subtype b - - - 0.0000000642 61.0
PYH2_k127_479485_34 Domain of unknown function (DUF4349) - - - 0.000001617 57.0
PYH2_k127_479485_35 Prokaryotic N-terminal methylation motif K02458 - - 0.00009946 53.0
PYH2_k127_479485_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.264e-210 667.0
PYH2_k127_479485_5 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 626.0
PYH2_k127_479485_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 510.0
PYH2_k127_479485_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 434.0
PYH2_k127_479485_8 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 418.0
PYH2_k127_479485_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 400.0
PYH2_k127_4811154_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 396.0
PYH2_k127_4811154_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 386.0
PYH2_k127_4811154_2 Methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003326 278.0
PYH2_k127_4811154_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000002391 233.0
PYH2_k127_4811154_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000004265 180.0
PYH2_k127_4811154_5 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000000000000000001157 172.0
PYH2_k127_4811154_6 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000001715 133.0
PYH2_k127_4811154_7 PFAM regulatory protein, MerR - - - 0.000000000000000000000000003996 114.0
PYH2_k127_4811154_8 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000002631 85.0
PYH2_k127_4811154_9 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000009364 81.0
PYH2_k127_4823005_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 1.004e-216 690.0
PYH2_k127_4823005_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 613.0
PYH2_k127_4823005_10 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003159 261.0
PYH2_k127_4823005_11 PFAM D5 N terminal like K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000002217 263.0
PYH2_k127_4823005_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000003671 208.0
PYH2_k127_4823005_13 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000603 196.0
PYH2_k127_4823005_14 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000001024 170.0
PYH2_k127_4823005_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000005477 168.0
PYH2_k127_4823005_16 DNA integration K14059 - - 0.0000000000000000000000000000000000000000001787 169.0
PYH2_k127_4823005_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000001694 128.0
PYH2_k127_4823005_18 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000006576 122.0
PYH2_k127_4823005_19 oligoendopeptidase F - - - 0.0000000000000000664 88.0
PYH2_k127_4823005_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 551.0
PYH2_k127_4823005_20 thiamine biosynthesis protein ThiS K03154 - - 0.00000000001051 67.0
PYH2_k127_4823005_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000002361 70.0
PYH2_k127_4823005_23 Pfam:N_methyl_2 - - - 0.00000002804 64.0
PYH2_k127_4823005_24 DNA integration K14059 - - 0.0000007365 52.0
PYH2_k127_4823005_25 Protein of unknown function (DUF421) - - - 0.000001102 55.0
PYH2_k127_4823005_27 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00003666 47.0
PYH2_k127_4823005_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 453.0
PYH2_k127_4823005_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 418.0
PYH2_k127_4823005_5 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 413.0
PYH2_k127_4823005_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 404.0
PYH2_k127_4823005_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 376.0
PYH2_k127_4823005_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 343.0
PYH2_k127_4823005_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 306.0
PYH2_k127_4830444_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 580.0
PYH2_k127_4830444_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 554.0
PYH2_k127_4830444_10 Dienelactone hydrolase family - - - 0.00000000000000004171 91.0
PYH2_k127_4830444_11 Adenylate cyclase - - - 0.0000000000000004085 81.0
PYH2_k127_4830444_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000006766 87.0
PYH2_k127_4830444_2 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
PYH2_k127_4830444_3 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 474.0
PYH2_k127_4830444_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 428.0
PYH2_k127_4830444_5 Sigma-54 factor interaction domain-containing protein K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 401.0
PYH2_k127_4830444_6 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001883 259.0
PYH2_k127_4830444_7 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000000000000007586 224.0
PYH2_k127_4830444_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000003412 213.0
PYH2_k127_4830444_9 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000001537 162.0
PYH2_k127_483927_0 Protein kinase domain K12132 - 2.7.11.1 2.49e-240 777.0
PYH2_k127_483927_1 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000002376 153.0
PYH2_k127_483927_2 - - - - 0.00000000000000000000000000001367 123.0
PYH2_k127_483927_3 SnoaL-like domain - - - 0.00000009516 54.0
PYH2_k127_483927_4 SnoaL-like domain - - - 0.0003703 43.0
PYH2_k127_4848522_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 619.0
PYH2_k127_4848522_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 445.0
PYH2_k127_4848522_2 Glycosyl transferase family 21 K19003 - 2.4.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 375.0
PYH2_k127_4848522_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 323.0
PYH2_k127_4848522_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 319.0
PYH2_k127_4848522_5 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004254 285.0
PYH2_k127_4848522_6 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000005847 181.0
PYH2_k127_4848522_7 PFAM OsmC family protein - - - 0.000000000000007338 75.0
PYH2_k127_4848522_8 Histidine kinase - - - 0.00000009682 56.0
PYH2_k127_4874330_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1611.0
PYH2_k127_4874330_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 502.0
PYH2_k127_4874330_10 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000000000000409 108.0
PYH2_k127_4874330_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 441.0
PYH2_k127_4874330_3 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 338.0
PYH2_k127_4874330_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 323.0
PYH2_k127_4874330_5 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001465 250.0
PYH2_k127_4874330_6 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000005636 186.0
PYH2_k127_4874330_7 Membrane - - - 0.0000000000000000000000000000000000000000000000155 187.0
PYH2_k127_4874330_8 Membrane K08988 - - 0.000000000000000000000000000000000001747 146.0
PYH2_k127_4874330_9 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000002417 115.0
PYH2_k127_4888462_0 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 485.0
PYH2_k127_4899610_0 Zinc carboxypeptidase K14054 - - 0.0 1219.0
PYH2_k127_4899610_1 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 553.0
PYH2_k127_4899610_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000009479 204.0
PYH2_k127_4899610_3 Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate K01708 - 4.2.1.42 0.00000000000000000000000000000000000004387 145.0
PYH2_k127_4918031_0 PFAM NHL repeat containing protein - - - 0.0000000000001017 76.0
PYH2_k127_4931818_0 Dienelactone hydrolase family - - - 2.616e-310 970.0
PYH2_k127_4931818_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5.889e-272 847.0
PYH2_k127_4931818_2 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 533.0
PYH2_k127_4931818_3 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000007425 203.0
PYH2_k127_4975435_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 396.0
PYH2_k127_4975435_1 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
PYH2_k127_4977090_0 succinate dehydrogenase - - - 1.369e-216 686.0
PYH2_k127_4977090_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 526.0
PYH2_k127_4977090_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0008381 44.0
PYH2_k127_4977090_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 478.0
PYH2_k127_4977090_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 481.0
PYH2_k127_4977090_4 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 439.0
PYH2_k127_4977090_5 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 392.0
PYH2_k127_4977090_6 OPT oligopeptide transporter protein - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 399.0
PYH2_k127_4977090_7 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 350.0
PYH2_k127_4977090_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 347.0
PYH2_k127_4977090_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 353.0
PYH2_k127_4988137_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009916 279.0
PYH2_k127_4988137_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000001578 211.0
PYH2_k127_4988137_2 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002114 220.0
PYH2_k127_4992989_0 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 3.087e-211 681.0
PYH2_k127_4992989_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 623.0
PYH2_k127_4992989_10 Alginate export - - - 0.00000000000005421 77.0
PYH2_k127_4992989_11 Belongs to the peptidase C1 family - - - 0.0000001451 64.0
PYH2_k127_4992989_12 Prolyl oligopeptidase family - - - 0.000958 45.0
PYH2_k127_4992989_2 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 555.0
PYH2_k127_4992989_3 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 510.0
PYH2_k127_4992989_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 500.0
PYH2_k127_4992989_5 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 474.0
PYH2_k127_4992989_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 381.0
PYH2_k127_4992989_7 - - - - 0.000000000000000000000000000000000001113 143.0
PYH2_k127_4992989_8 - - - - 0.0000000000000000000000000005133 121.0
PYH2_k127_4999411_0 Belongs to the binding-protein-dependent transport system permease family K17214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 386.0
PYH2_k127_4999411_1 Xylose isomerase domain protein TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 291.0
PYH2_k127_4999411_2 import. Responsible for energy coupling to the transport system K17215 - - 0.000000000000000000000000001464 113.0
PYH2_k127_5042061_0 arylsulfatase activity K01137,K01138 - 3.1.6.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 536.0
PYH2_k127_5042061_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 427.0
PYH2_k127_5042061_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000006633 92.0
PYH2_k127_5042061_3 Glycosyl hydrolases family 18 K01183 - 3.2.1.14 0.0000000002812 73.0
PYH2_k127_5060603_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 354.0
PYH2_k127_5060603_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 317.0
PYH2_k127_5060603_2 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 269.0
PYH2_k127_5069255_0 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 557.0
PYH2_k127_5069255_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 408.0
PYH2_k127_5069255_2 PFAM Beta-lactamase - - - 0.00000000000000000000000000000004972 131.0
PYH2_k127_5069255_3 ubiE/COQ5 methyltransferase family - - - 0.0000005094 59.0
PYH2_k127_508379_0 Belongs to the peptidase M24B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 432.0
PYH2_k127_508379_1 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000009318 119.0
PYH2_k127_5086053_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 565.0
PYH2_k127_5090914_0 COG0582 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 417.0
PYH2_k127_5090914_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
PYH2_k127_5090914_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000946 212.0
PYH2_k127_5090914_3 Gaf domain K01768,K11527,K18967,K21009 - 2.7.13.3,2.7.7.65,4.6.1.1 0.0000000000000000000000000000000000000000000008153 191.0
PYH2_k127_5090914_4 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000011 147.0
PYH2_k127_5090914_5 thiolester hydrolase activity - - - 0.0000000000000000000003001 104.0
PYH2_k127_5090914_6 Integrase - - - 0.000001657 51.0
PYH2_k127_5092841_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 549.0
PYH2_k127_5092841_1 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 437.0
PYH2_k127_5092841_2 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 379.0
PYH2_k127_5092841_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 324.0
PYH2_k127_5092841_4 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 300.0
PYH2_k127_5092841_5 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007897 269.0
PYH2_k127_5092841_6 membrane - - - 0.00000000000000000000000000000000000000000000000004049 190.0
PYH2_k127_5097134_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 612.0
PYH2_k127_5097134_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 418.0
PYH2_k127_5097134_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 392.0
PYH2_k127_5097134_3 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 373.0
PYH2_k127_5097134_4 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000009112 252.0
PYH2_k127_5097134_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000005211 129.0
PYH2_k127_5097134_6 Alpha beta K06889 - - 0.000000000000006226 85.0
PYH2_k127_5097134_7 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0004845 45.0
PYH2_k127_5103578_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 486.0
PYH2_k127_5103578_1 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000001432 218.0
PYH2_k127_5103578_2 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000009543 84.0
PYH2_k127_5103578_3 Phospholipid methyltransferase - - - 0.00000000000101 76.0
PYH2_k127_5103578_4 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000398 72.0
PYH2_k127_5103578_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0004604 43.0
PYH2_k127_5141324_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1197.0
PYH2_k127_5141324_1 Beta-lactamase - - - 1.504e-196 629.0
PYH2_k127_5141324_10 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 395.0
PYH2_k127_5141324_11 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 391.0
PYH2_k127_5141324_12 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 340.0
PYH2_k127_5141324_13 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 299.0
PYH2_k127_5141324_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 295.0
PYH2_k127_5141324_15 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 284.0
PYH2_k127_5141324_16 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002066 264.0
PYH2_k127_5141324_17 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) K00917 - 2.7.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000004759 262.0
PYH2_k127_5141324_18 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
PYH2_k127_5141324_19 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000002099 254.0
PYH2_k127_5141324_2 PFAM amidohydrolase K01464 - 3.5.2.2 4.309e-195 619.0
PYH2_k127_5141324_20 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000002557 171.0
PYH2_k127_5141324_21 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000007013 177.0
PYH2_k127_5141324_22 DeoR C terminal sensor domain K02081,K20271 - - 0.000000000000000000000000000000000003198 149.0
PYH2_k127_5141324_23 PFAM Cyclic nucleotide-binding domain - - - 0.00000000000000000000000001879 113.0
PYH2_k127_5141324_24 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000001042 104.0
PYH2_k127_5141324_25 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K18456 - 3.5.4.28,3.5.4.31,3.5.4.32 0.000000002441 58.0
PYH2_k127_5141324_3 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 589.0
PYH2_k127_5141324_4 L-rhamnose isomerase K01813 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 588.0
PYH2_k127_5141324_5 PFAM Short-chain dehydrogenase reductase SDR K00068 - 1.1.1.140 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 569.0
PYH2_k127_5141324_6 Alcohol dehydrogenase GroES-like domain K19956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 499.0
PYH2_k127_5141324_7 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 473.0
PYH2_k127_5141324_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 453.0
PYH2_k127_5141324_9 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 427.0
PYH2_k127_5146108_0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006798 282.0
PYH2_k127_5153071_0 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 357.0
PYH2_k127_5153071_1 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 354.0
PYH2_k127_5153071_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 314.0
PYH2_k127_5153071_3 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000001312 182.0
PYH2_k127_5153071_4 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000000000000000000000000000000000001529 149.0
PYH2_k127_5153071_5 ECF sigma factor K03088 - - 0.000000000000000000001334 106.0
PYH2_k127_5153071_6 N-terminal double-glycine peptidase domain K06147 - - 0.0000000000000004392 85.0
PYH2_k127_5153071_7 Double zinc ribbon - - - 0.00000000000007962 82.0
PYH2_k127_5153071_8 Yip1 domain - - - 0.0000002365 61.0
PYH2_k127_5160764_0 PFAM sulfatase K01130 - 3.1.6.1 0.0 1195.0
PYH2_k127_5160764_1 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000003005 114.0
PYH2_k127_5160764_2 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000007727 91.0
PYH2_k127_5210489_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 310.0
PYH2_k127_5210489_1 COG1226 Kef-type K transport systems K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000005681 228.0
PYH2_k127_5217826_0 Radical SAM - - - 6.8e-309 957.0
PYH2_k127_5217826_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.244e-217 684.0
PYH2_k127_5217826_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 407.0
PYH2_k127_5217826_11 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 387.0
PYH2_k127_5217826_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 389.0
PYH2_k127_5217826_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 331.0
PYH2_k127_5217826_14 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 326.0
PYH2_k127_5217826_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 278.0
PYH2_k127_5217826_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001265 257.0
PYH2_k127_5217826_17 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002381 261.0
PYH2_k127_5217826_18 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003425 253.0
PYH2_k127_5217826_19 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000003151 230.0
PYH2_k127_5217826_2 lactate metabolic process - - - 4.375e-216 689.0
PYH2_k127_5217826_20 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000005759 221.0
PYH2_k127_5217826_21 - K01992,K19341 - - 0.00000000000000000000000000000000000000000000003784 181.0
PYH2_k127_5217826_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000001319 172.0
PYH2_k127_5217826_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000004066 154.0
PYH2_k127_5217826_24 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000001099 154.0
PYH2_k127_5217826_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000002693 150.0
PYH2_k127_5217826_26 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000926 143.0
PYH2_k127_5217826_27 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.000000000000000000000000001082 116.0
PYH2_k127_5217826_28 Tetratricopeptide repeat - - - 0.000000000000000000007389 106.0
PYH2_k127_5217826_29 Ribosomal L28 family K02902 - - 0.0000000000000000008713 87.0
PYH2_k127_5217826_3 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 484.0
PYH2_k127_5217826_30 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000001966 58.0
PYH2_k127_5217826_4 NAD binding K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 478.0
PYH2_k127_5217826_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 442.0
PYH2_k127_5217826_6 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 410.0
PYH2_k127_5217826_7 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
PYH2_k127_5217826_8 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 407.0
PYH2_k127_5217826_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 401.0
PYH2_k127_5221561_0 amine dehydrogenase activity K14647,K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 304.0
PYH2_k127_5221561_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000283 203.0
PYH2_k127_5250132_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004803 273.0
PYH2_k127_5250132_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000001959 192.0
PYH2_k127_5250132_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000003344 134.0
PYH2_k127_5250132_3 Two component transcriptional regulator, LuxR family - - - 0.00000033 57.0
PYH2_k127_5264193_0 Putative esterase - - - 2.612e-268 843.0
PYH2_k127_5264193_1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 448.0
PYH2_k127_5264193_2 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 425.0
PYH2_k127_5264193_3 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 366.0
PYH2_k127_5264193_4 Prephenate dehydratase K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 335.0
PYH2_k127_5264193_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006198 276.0
PYH2_k127_5265610_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1740.0
PYH2_k127_5265610_1 OPT oligopeptide transporter protein - - - 7.568e-313 970.0
PYH2_k127_5265610_10 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 462.0
PYH2_k127_5265610_11 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 436.0
PYH2_k127_5265610_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 422.0
PYH2_k127_5265610_13 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 373.0
PYH2_k127_5265610_14 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 340.0
PYH2_k127_5265610_15 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006663 256.0
PYH2_k127_5265610_16 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000002153 180.0
PYH2_k127_5265610_17 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000001387 99.0
PYH2_k127_5265610_18 cellulase activity K01387 - 3.4.24.3 0.000000000000001156 84.0
PYH2_k127_5265610_19 response regulator, receiver - - - 0.0000000000000183 78.0
PYH2_k127_5265610_2 cellulose binding - - - 8.077e-285 912.0
PYH2_k127_5265610_20 RNA polymerase sigma factor K03088 - - 0.0000000000792 72.0
PYH2_k127_5265610_21 - - - - 0.00000001133 66.0
PYH2_k127_5265610_22 Cytochrome c - - - 0.0003352 48.0
PYH2_k127_5265610_23 - - - - 0.0005955 49.0
PYH2_k127_5265610_24 domain, Protein - - - 0.000879 53.0
PYH2_k127_5265610_3 GTP-binding protein TypA K06207 - - 7.111e-270 847.0
PYH2_k127_5265610_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 609.0
PYH2_k127_5265610_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 600.0
PYH2_k127_5265610_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 521.0
PYH2_k127_5265610_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 513.0
PYH2_k127_5265610_8 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 460.0
PYH2_k127_5265610_9 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 447.0
PYH2_k127_5355706_0 Domain of unknown function (DUF1998) K06877 - - 4.366e-303 947.0
PYH2_k127_5355706_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 7.181e-198 626.0
PYH2_k127_5355706_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000003549 147.0
PYH2_k127_5355706_11 Belongs to the enoyl-CoA hydratase isomerase family K01692,K13238 - 4.2.1.17,5.3.3.8 0.0000000000000000000000000000000000003334 150.0
PYH2_k127_5355706_12 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000418 145.0
PYH2_k127_5355706_13 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000001445 136.0
PYH2_k127_5355706_14 DNA-binding transcription factor activity - - - 0.00000000000000000000000000191 116.0
PYH2_k127_5355706_15 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.00000000000000000001503 103.0
PYH2_k127_5355706_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 462.0
PYH2_k127_5355706_3 arsenite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 417.0
PYH2_k127_5355706_4 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 397.0
PYH2_k127_5355706_5 xaa-pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 325.0
PYH2_k127_5355706_6 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003369 288.0
PYH2_k127_5355706_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000004284 250.0
PYH2_k127_5355706_8 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000067 255.0
PYH2_k127_5355706_9 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000004251 229.0
PYH2_k127_5364923_0 helicase activity - - - 5.512e-260 834.0
PYH2_k127_5364923_1 Amino acid permease - - - 2.793e-246 782.0
PYH2_k127_5364923_10 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000007086 168.0
PYH2_k127_5364923_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000157 139.0
PYH2_k127_5364923_12 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000009122 116.0
PYH2_k127_5364923_13 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000001461 129.0
PYH2_k127_5364923_14 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000004215 110.0
PYH2_k127_5364923_15 EamA-like transporter family - - - 0.000000000000000000001523 100.0
PYH2_k127_5364923_16 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000002704 76.0
PYH2_k127_5364923_17 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000005122 56.0
PYH2_k127_5364923_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000926 49.0
PYH2_k127_5364923_2 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 518.0
PYH2_k127_5364923_3 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 439.0
PYH2_k127_5364923_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 419.0
PYH2_k127_5364923_5 glycosyl transferase family 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 377.0
PYH2_k127_5364923_6 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 316.0
PYH2_k127_5364923_7 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
PYH2_k127_5364923_8 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 299.0
PYH2_k127_5364923_9 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 299.0
PYH2_k127_5411229_0 Integrase - - - 0.00000000000000000000000000000000000000003082 154.0
PYH2_k127_5411229_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000004555 94.0
PYH2_k127_5411229_2 PFAM Methyltransferase type 11 - - - 0.00000007914 64.0
PYH2_k127_5411229_3 Cellulase (glycosyl hydrolase family 5) - - - 0.000006589 54.0
PYH2_k127_5411229_4 Integrase - - - 0.000154 49.0
PYH2_k127_5411229_5 Pkd domain containing protein - - - 0.0001894 49.0
PYH2_k127_5414099_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001652 191.0
PYH2_k127_5414099_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000002342 141.0
PYH2_k127_560385_0 serine-type peptidase activity K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 445.0
PYH2_k127_560385_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
PYH2_k127_560385_2 His Kinase A (phosphoacceptor) domain K02484,K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001661 251.0
PYH2_k127_5608503_0 Sulfatase - - - 2.525e-217 686.0
PYH2_k127_5608503_1 Periplasmic copper-binding protein (NosD) K01209 - 3.2.1.55 1.055e-201 646.0
PYH2_k127_5608503_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K08137 - - 9.534e-194 618.0
PYH2_k127_5608503_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 347.0
PYH2_k127_5608503_4 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 249.0
PYH2_k127_5608503_5 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000001706 194.0
PYH2_k127_5608503_6 transcription activator, effector binding K13652 - - 0.00000000000000000000000000000000000000000003487 168.0
PYH2_k127_5608503_7 Beta-lactamase K17836 - 3.5.2.6 0.00009894 49.0
PYH2_k127_5621447_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000001313 188.0
PYH2_k127_5644020_0 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 526.0
PYH2_k127_5649579_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 4.784e-264 827.0
PYH2_k127_5649579_1 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 476.0
PYH2_k127_5649579_2 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003111 260.0
PYH2_k127_5653342_0 Hydantoinase/oxoprolinase - - - 9.166e-231 735.0
PYH2_k127_5653342_1 gluconate transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 381.0
PYH2_k127_5653342_10 transcriptional K03710 - - 0.00008782 48.0
PYH2_k127_5653342_11 ligase activity - - - 0.0004221 50.0
PYH2_k127_5653342_2 Protein of unknown function (DUF4127) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 328.0
PYH2_k127_5653342_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000002445 263.0
PYH2_k127_5653342_4 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) K01788 - 5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000005501 235.0
PYH2_k127_5653342_5 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000001217 195.0
PYH2_k127_5653342_6 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000004051 145.0
PYH2_k127_5653342_7 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.00000000000000000000000000000000131 133.0
PYH2_k127_5653342_8 amidotransferase, A subunit K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001864 121.0
PYH2_k127_5653342_9 - - - - 0.00005288 55.0
PYH2_k127_565360_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.811e-265 843.0
PYH2_k127_565360_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.683e-250 785.0
PYH2_k127_565360_10 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000117 219.0
PYH2_k127_565360_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000002513 195.0
PYH2_k127_565360_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000003983 168.0
PYH2_k127_565360_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000003186 141.0
PYH2_k127_565360_14 Protein conserved in bacteria - - - 0.000000000000000000000000000000002333 141.0
PYH2_k127_565360_15 Cold shock protein domain K03704 - - 0.000000000000000000000001011 104.0
PYH2_k127_565360_16 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000001397 107.0
PYH2_k127_565360_17 PFAM DRTGG domain - - - 0.00000000000000007213 83.0
PYH2_k127_565360_2 TonB dependent receptor - - - 1.134e-195 634.0
PYH2_k127_565360_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 452.0
PYH2_k127_565360_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K18916 - 1.1.1.26,1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 407.0
PYH2_k127_565360_5 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 358.0
PYH2_k127_565360_6 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 347.0
PYH2_k127_565360_7 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005128 287.0
PYH2_k127_565360_8 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007471 258.0
PYH2_k127_565360_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
PYH2_k127_5655341_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 1.011e-234 741.0
PYH2_k127_5655341_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001636 246.0
PYH2_k127_5655341_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000003076 139.0
PYH2_k127_5655341_3 Tetratricopeptide repeat - - - 0.000000000000000000006018 102.0
PYH2_k127_5655341_4 ECF sigma factor K03088 - - 0.0000000000000000000303 100.0
PYH2_k127_5655341_5 BlaR1 peptidase M56 - - - 0.000000000008141 72.0
PYH2_k127_5655341_6 energy transducer activity K02487,K03832,K06596 - - 0.000000009638 66.0
PYH2_k127_5658808_0 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 610.0
PYH2_k127_5658808_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 523.0
PYH2_k127_5658808_10 nuclease activity - - - 0.0000000000000000000000000000000001647 139.0
PYH2_k127_5658808_11 Protein of unknown function (DUF3106) - - - 0.00000000001037 72.0
PYH2_k127_5658808_12 - - - - 0.00009277 45.0
PYH2_k127_5658808_13 PFAM Protein kinase domain - - - 0.000275 53.0
PYH2_k127_5658808_14 Anti-sigma-K factor rskA - - - 0.0009029 50.0
PYH2_k127_5658808_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 526.0
PYH2_k127_5658808_3 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 432.0
PYH2_k127_5658808_4 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 387.0
PYH2_k127_5658808_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 370.0
PYH2_k127_5658808_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000627 289.0
PYH2_k127_5658808_7 glucokinase activity K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.00000000000000000000000000000000000000000000007407 183.0
PYH2_k127_5658808_8 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000007051 153.0
PYH2_k127_5658808_9 HDOD domain - - - 0.000000000000000000000000000000000001102 151.0
PYH2_k127_5669071_0 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 539.0
PYH2_k127_5669071_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 522.0
PYH2_k127_5669071_10 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000005038 186.0
PYH2_k127_5669071_11 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000002791 148.0
PYH2_k127_5669071_12 COGs COG4299 conserved - - - 0.00000000000000006384 83.0
PYH2_k127_5669071_13 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0000000003849 72.0
PYH2_k127_5669071_14 transcriptional regulator - - - 0.00000007233 62.0
PYH2_k127_5669071_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000002799 57.0
PYH2_k127_5669071_2 BNR repeat-like domain K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 489.0
PYH2_k127_5669071_3 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 458.0
PYH2_k127_5669071_4 Mur ligase middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 461.0
PYH2_k127_5669071_5 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 302.0
PYH2_k127_5669071_6 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 294.0
PYH2_k127_5669071_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000009535 249.0
PYH2_k127_5669071_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000003684 218.0
PYH2_k127_5669071_9 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000007869 219.0
PYH2_k127_5680555_0 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000005021 219.0
PYH2_k127_5680555_1 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000001148 199.0
PYH2_k127_5680555_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000005578 144.0
PYH2_k127_5680555_3 oxidoreductase activity - - - 0.0000000229 60.0
PYH2_k127_5721950_0 glutamine synthetase K01915 - 6.3.1.2 2.141e-196 622.0
PYH2_k127_5721950_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 590.0
PYH2_k127_5721950_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 516.0
PYH2_k127_5721950_3 alcohol dehydrogenase K00043 - 1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 340.0
PYH2_k127_5721950_4 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 302.0
PYH2_k127_5721950_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000226 290.0
PYH2_k127_5721950_6 transmembrane transporter activity K02445,K07783 - - 0.000000000000000000000000000000000000000000000000000000000000004117 238.0
PYH2_k127_5721950_7 phosphatase activity K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000000000000000000000000000000007343 215.0
PYH2_k127_5721950_8 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000519 157.0
PYH2_k127_5721950_9 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000006502 126.0
PYH2_k127_5724304_0 Glycogen debranching enzyme K05989 - 3.2.1.40 0.0 1202.0
PYH2_k127_5724304_1 membrane organization K07277,K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 597.0
PYH2_k127_5724304_2 Ami_3 K01448 - 3.5.1.28 0.0001251 51.0
PYH2_k127_57390_0 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 527.0
PYH2_k127_57390_1 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 267.0
PYH2_k127_57390_2 COG0524 Sugar kinases, ribokinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000009106 241.0
PYH2_k127_57390_3 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.0000000000000000000000000000000000000000000000000000000000000009124 244.0
PYH2_k127_57390_4 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000000501 196.0
PYH2_k127_57390_5 Cobalt transport protein K02008 - - 0.0000000000000000000000000007918 122.0
PYH2_k127_57390_6 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.00000052 57.0
PYH2_k127_5746156_0 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000007707 231.0
PYH2_k127_5746156_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000006832 105.0
PYH2_k127_5746156_2 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001517 99.0
PYH2_k127_5746156_3 - - - - 0.00000000002139 72.0
PYH2_k127_5746156_4 Integrase core domain - - - 0.00007884 45.0
PYH2_k127_5755232_0 metallocarboxypeptidase activity K14054 - - 0.0 1150.0
PYH2_k127_5755232_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.907e-307 962.0
PYH2_k127_5755232_10 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 473.0
PYH2_k127_5755232_11 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 469.0
PYH2_k127_5755232_12 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 466.0
PYH2_k127_5755232_13 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 462.0
PYH2_k127_5755232_14 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 434.0
PYH2_k127_5755232_15 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 429.0
PYH2_k127_5755232_16 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 395.0
PYH2_k127_5755232_17 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
PYH2_k127_5755232_18 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
PYH2_k127_5755232_19 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 351.0
PYH2_k127_5755232_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.759e-298 937.0
PYH2_k127_5755232_20 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 342.0
PYH2_k127_5755232_21 tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 338.0
PYH2_k127_5755232_22 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
PYH2_k127_5755232_23 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002099 276.0
PYH2_k127_5755232_24 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003554 269.0
PYH2_k127_5755232_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001381 261.0
PYH2_k127_5755232_26 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000341 232.0
PYH2_k127_5755232_27 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
PYH2_k127_5755232_28 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000001794 213.0
PYH2_k127_5755232_29 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000002593 201.0
PYH2_k127_5755232_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.975e-256 805.0
PYH2_k127_5755232_30 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000002022 199.0
PYH2_k127_5755232_31 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000003751 186.0
PYH2_k127_5755232_32 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000063 185.0
PYH2_k127_5755232_33 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000001284 174.0
PYH2_k127_5755232_34 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000001286 180.0
PYH2_k127_5755232_35 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000002622 149.0
PYH2_k127_5755232_36 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000001095 126.0
PYH2_k127_5755232_37 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000002971 118.0
PYH2_k127_5755232_38 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000001387 119.0
PYH2_k127_5755232_39 Putative adhesin - - - 0.000000000000000000000000001735 129.0
PYH2_k127_5755232_4 aminopeptidase activity K07004 - - 5.381e-225 719.0
PYH2_k127_5755232_40 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000001768 103.0
PYH2_k127_5755232_41 - - - - 0.000000000000000000001795 102.0
PYH2_k127_5755232_42 - - - - 0.0000000000000000002748 99.0
PYH2_k127_5755232_43 - - - - 0.000000000000000001567 96.0
PYH2_k127_5755232_44 multi-organism process K03195 - - 0.000000000000000002631 93.0
PYH2_k127_5755232_45 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000844 91.0
PYH2_k127_5755232_47 DnaJ molecular chaperone homology domain - - - 0.000000005646 68.0
PYH2_k127_5755232_48 Putative adhesin - - - 0.000001234 53.0
PYH2_k127_5755232_49 PFAM HD domain K06950 - - 0.000001296 59.0
PYH2_k127_5755232_5 Peptidase dimerisation domain K12941 - - 2.756e-222 702.0
PYH2_k127_5755232_50 protein trimerization - - - 0.000001836 59.0
PYH2_k127_5755232_52 metal-dependent membrane protease - - - 0.0006012 50.0
PYH2_k127_5755232_6 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 1.611e-206 658.0
PYH2_k127_5755232_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 603.0
PYH2_k127_5755232_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 535.0
PYH2_k127_5755232_9 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 516.0
PYH2_k127_5757819_0 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 7.09e-257 826.0
PYH2_k127_5757819_1 Belongs to the IlvD Edd family K22396 - 4.2.1.82 5.126e-247 779.0
PYH2_k127_5757819_10 - - - - 0.000000000000000001218 100.0
PYH2_k127_5757819_11 Nitroreductase family - - - 0.000000000011 67.0
PYH2_k127_5757819_12 Hexapeptide repeat of succinyl-transferase - - - 0.0000000003077 70.0
PYH2_k127_5757819_2 Rhodanese-like domain K01069 - 3.1.2.6 1.31e-211 666.0
PYH2_k127_5757819_3 L-fucose isomerase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 425.0
PYH2_k127_5757819_4 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 302.0
PYH2_k127_5757819_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000005638 241.0
PYH2_k127_5757819_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000009658 223.0
PYH2_k127_5757819_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000006132 186.0
PYH2_k127_5757819_8 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.000000000000000000000000000000000000001051 150.0
PYH2_k127_5757819_9 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000008044 113.0
PYH2_k127_5758682_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 445.0
PYH2_k127_5758682_1 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 427.0
PYH2_k127_5758682_10 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000004718 225.0
PYH2_k127_5758682_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000004166 204.0
PYH2_k127_5758682_12 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000005146 161.0
PYH2_k127_5758682_13 O-Antigen ligase K18814 - - 0.000008518 51.0
PYH2_k127_5758682_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 420.0
PYH2_k127_5758682_3 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 405.0
PYH2_k127_5758682_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 337.0
PYH2_k127_5758682_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 329.0
PYH2_k127_5758682_6 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 300.0
PYH2_k127_5758682_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 294.0
PYH2_k127_5758682_8 macromolecule localization K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000006227 237.0
PYH2_k127_5758682_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000004085 238.0
PYH2_k127_5763656_0 alpha-L-rhamnosidase - - - 0.0 1127.0
PYH2_k127_5763656_1 AMP-binding enzyme C-terminal domain K01897,K18660 - 6.2.1.3 6.328e-209 661.0
PYH2_k127_5763656_10 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000001098 164.0
PYH2_k127_5763656_11 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000005975 157.0
PYH2_k127_5763656_12 Nitroreductase family - - - 0.0000000000000000000000000000000006193 143.0
PYH2_k127_5763656_13 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000002476 140.0
PYH2_k127_5763656_14 Alpha/beta hydrolase family K06889 - - 0.0000000000000001061 89.0
PYH2_k127_5763656_15 alpha beta K06889 - - 0.0000000000000003593 87.0
PYH2_k127_5763656_2 PFAM Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 524.0
PYH2_k127_5763656_3 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 474.0
PYH2_k127_5763656_4 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 408.0
PYH2_k127_5763656_5 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 376.0
PYH2_k127_5763656_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 359.0
PYH2_k127_5763656_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005081 209.0
PYH2_k127_5763656_8 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.00000000000000000000000000000000000000000000000000000000008087 210.0
PYH2_k127_5763656_9 STAS-like domain of unknown function (DUF4325) - - - 0.0000000000000000000000000000000000000000000000000001215 200.0
PYH2_k127_5764289_0 Domain of unknown function (DUF5107) - - - 8.416e-267 860.0
PYH2_k127_5764289_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 373.0
PYH2_k127_5764289_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000003218 123.0
PYH2_k127_5764289_11 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000006139 86.0
PYH2_k127_5764289_12 Methyltransferase domain - - - 0.000000000001807 77.0
PYH2_k127_5764289_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000004364 70.0
PYH2_k127_5764289_2 PFAM peptidase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 359.0
PYH2_k127_5764289_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 344.0
PYH2_k127_5764289_4 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 309.0
PYH2_k127_5764289_5 GtrA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
PYH2_k127_5764289_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000002007 263.0
PYH2_k127_5764289_7 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000001904 198.0
PYH2_k127_5764289_8 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000001832 191.0
PYH2_k127_5764289_9 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000954 200.0
PYH2_k127_5773276_0 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 550.0
PYH2_k127_5778657_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000309 295.0
PYH2_k127_5778657_1 Uncharacterised protein family (UPF0158) - - - 0.000000000000000000000282 103.0
PYH2_k127_5782872_0 Amino acid kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 486.0
PYH2_k127_5782872_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 480.0
PYH2_k127_5782872_10 Belongs to the ompA family - - - 0.000000004082 63.0
PYH2_k127_5782872_11 polyphosphate kinase K22468 - 2.7.4.1 0.00000002126 63.0
PYH2_k127_5782872_2 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 348.0
PYH2_k127_5782872_3 pyrroline-5-carboxylate reductase activity K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 304.0
PYH2_k127_5782872_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
PYH2_k127_5782872_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000001592 222.0
PYH2_k127_5782872_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000208 197.0
PYH2_k127_5782872_7 Integrase core domain - - - 0.00000000000000000000000000002159 120.0
PYH2_k127_5782872_8 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000004086 105.0
PYH2_k127_5782872_9 - - - - 0.0000000000000000185 90.0
PYH2_k127_5795632_0 transport - - - 3.064e-262 846.0
PYH2_k127_5795632_1 PFAM Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 476.0
PYH2_k127_5795632_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000005449 246.0
PYH2_k127_5795632_3 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000002646 180.0
PYH2_k127_5795632_4 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000009769 171.0
PYH2_k127_5795632_5 nuclear chromosome segregation - - - 0.000000000000000000000000000001283 134.0
PYH2_k127_5795632_6 - - - - 0.000000000009172 68.0
PYH2_k127_5803242_0 Belongs to the glycosyl hydrolase 2 family - - - 7.107e-273 856.0
PYH2_k127_5803242_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 2.362e-209 697.0
PYH2_k127_5803242_2 Protein of unknown function (DUF4038) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 576.0
PYH2_k127_5803242_3 DinB family - - - 0.00000000000000000000000000003243 122.0
PYH2_k127_5803242_4 efflux transmembrane transporter activity - - - 0.00000000004471 68.0
PYH2_k127_5805462_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 436.0
PYH2_k127_5805462_1 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000233 155.0
PYH2_k127_5805462_2 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000009772 97.0
PYH2_k127_5805462_3 - - - - 0.000000000000002445 77.0
PYH2_k127_5805462_4 transmembrane transporter activity - - - 0.0000000000000167 75.0
PYH2_k127_5805462_5 AhpC/TSA family - - - 0.00000000005586 67.0
PYH2_k127_5805462_6 ACT domain K09707 - - 0.00001419 54.0
PYH2_k127_5818152_0 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 591.0
PYH2_k127_5818152_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 531.0
PYH2_k127_5818152_2 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000002652 158.0
PYH2_k127_5818152_3 Integrase core domain - - - 0.00000000000000000000001433 102.0
PYH2_k127_5830959_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1054.0
PYH2_k127_5830959_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000003364 168.0
PYH2_k127_5840588_0 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 350.0
PYH2_k127_5840588_1 - - - - 0.00000000000000000000000000007052 127.0
PYH2_k127_5840588_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000003872 76.0
PYH2_k127_5840588_3 - - - - 0.000001831 55.0
PYH2_k127_5868810_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7e-215 683.0
PYH2_k127_5868810_1 ABC transporter K06147,K18890 - - 1.456e-200 645.0
PYH2_k127_5868810_10 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000004922 209.0
PYH2_k127_5868810_11 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000001629 194.0
PYH2_k127_5868810_12 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000004402 171.0
PYH2_k127_5868810_13 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000004709 177.0
PYH2_k127_5868810_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.000000000000000000000000000000000001358 142.0
PYH2_k127_5868810_15 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000005574 139.0
PYH2_k127_5868810_16 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000006066 116.0
PYH2_k127_5868810_17 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000083 110.0
PYH2_k127_5868810_18 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001775 69.0
PYH2_k127_5868810_19 Belongs to the BshC family K22136 - - 0.000000009419 67.0
PYH2_k127_5868810_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 576.0
PYH2_k127_5868810_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 394.0
PYH2_k127_5868810_4 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 390.0
PYH2_k127_5868810_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 368.0
PYH2_k127_5868810_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
PYH2_k127_5868810_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009183 254.0
PYH2_k127_5868810_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K21062 - 3.5.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000003663 250.0
PYH2_k127_5868810_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000008321 220.0
PYH2_k127_5891638_0 Sortilin, neurotensin receptor 3, - - - 0.0 1149.0
PYH2_k127_5891638_1 Carboxypeptidase regulatory-like domain - - - 0.0 1077.0
PYH2_k127_5891638_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 486.0
PYH2_k127_5891638_3 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.00000000000000000000000000000000000000000000001927 181.0
PYH2_k127_5891638_4 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000001753 169.0
PYH2_k127_5891638_5 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000036 138.0
PYH2_k127_5891638_6 membrane - - - 0.00000003244 66.0
PYH2_k127_5893972_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1235.0
PYH2_k127_5893972_1 Melibiase K07407 - 3.2.1.22 1.668e-260 821.0
PYH2_k127_5893972_10 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 379.0
PYH2_k127_5893972_11 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 370.0
PYH2_k127_5893972_12 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 342.0
PYH2_k127_5893972_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004524 273.0
PYH2_k127_5893972_14 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003065 262.0
PYH2_k127_5893972_15 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000005288 225.0
PYH2_k127_5893972_16 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000001371 208.0
PYH2_k127_5893972_17 Uncharacterized protein domain (DUF2202) - - - 0.000000000000000000000000000000000000000000000001251 185.0
PYH2_k127_5893972_18 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000003503 159.0
PYH2_k127_5893972_19 His Kinase A (phosphoacceptor) domain K07709 - 2.7.13.3 0.00000000000000000000000000000000000000179 164.0
PYH2_k127_5893972_2 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 618.0
PYH2_k127_5893972_20 arabinan catabolic process - - - 0.000000000000000000000000000000000001391 151.0
PYH2_k127_5893972_21 Belongs to the glycosyl hydrolase 43 family K20276 - - 0.000000000000000000000000000000000009823 158.0
PYH2_k127_5893972_22 - - - - 0.00000000000000000000000000003088 128.0
PYH2_k127_5893972_23 Biotin-lipoyl like - - - 0.0000000000000000000003097 109.0
PYH2_k127_5893972_24 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000006492 108.0
PYH2_k127_5893972_25 - - - - 0.000000000000000000004393 96.0
PYH2_k127_5893972_26 Protein of unknown function (DUF2892) - - - 0.00000000000000000001592 96.0
PYH2_k127_5893972_27 Domain of unknown function (DUF4405) - - - 0.00000000000000000003374 96.0
PYH2_k127_5893972_28 ECF sigma factor K03088 - - 0.000000000000000000165 95.0
PYH2_k127_5893972_29 PFAM Bacterial regulatory protein, arsR family K03892 - - 0.0000000000000000005219 91.0
PYH2_k127_5893972_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 532.0
PYH2_k127_5893972_31 - - - - 0.00000000000004329 74.0
PYH2_k127_5893972_32 Zinc ribbon domain - - - 0.00000001917 61.0
PYH2_k127_5893972_33 Heavy-metal resistance - - - 0.0000002374 58.0
PYH2_k127_5893972_34 - - - - 0.000006736 51.0
PYH2_k127_5893972_35 oxidoreductase activity - - - 0.00001286 54.0
PYH2_k127_5893972_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 527.0
PYH2_k127_5893972_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 504.0
PYH2_k127_5893972_6 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 456.0
PYH2_k127_5893972_7 response regulator K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 425.0
PYH2_k127_5893972_8 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 406.0
PYH2_k127_5893972_9 Catalyzes the reduction of tatronate semialdehyde to D- glycerate K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 383.0
PYH2_k127_5914462_0 Resolvase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 522.0
PYH2_k127_5914462_1 Integrase - - - 0.0000000000000000000007789 98.0
PYH2_k127_5919787_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 7.744e-295 936.0
PYH2_k127_5919787_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 3.176e-235 745.0
PYH2_k127_5919787_2 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 259.0
PYH2_k127_5919787_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000007158 220.0
PYH2_k127_5919787_4 Domain of unknown function (DUF1820) - - - 0.000000000000000000000000000003612 132.0
PYH2_k127_5919787_5 Ferredoxin - - - 0.00000000000000000002428 105.0
PYH2_k127_5961256_0 slime layer polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 377.0
PYH2_k127_5961256_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 363.0
PYH2_k127_5961256_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 355.0
PYH2_k127_5961256_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000001273 216.0
PYH2_k127_5961256_4 PFAM regulatory protein GntR HTH K07979 - - 0.000000000000000000000006579 105.0
PYH2_k127_596508_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1006.0
PYH2_k127_596508_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 4.172e-290 906.0
PYH2_k127_596508_10 Beta-ketoacyl synthase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001721 249.0
PYH2_k127_596508_11 dioxygenase K00464 - 1.13.11.75 0.0000000000000000000000000000000000000000000000000000003006 211.0
PYH2_k127_596508_12 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000001351 190.0
PYH2_k127_596508_13 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K07001 - - 0.0000000000000000000000000000000000001823 161.0
PYH2_k127_596508_14 reverse transcriptase K00986 - 2.7.7.49 0.000000000000000000000000001088 117.0
PYH2_k127_596508_15 cyclic nucleotide binding K10914 - - 0.0000000000000000009234 97.0
PYH2_k127_596508_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000002068 67.0
PYH2_k127_596508_17 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000005909 54.0
PYH2_k127_596508_18 regulatory protein TetR - - - 0.000003104 59.0
PYH2_k127_596508_19 protein conserved in bacteria - - - 0.000007386 57.0
PYH2_k127_596508_2 TonB dependent receptor - - - 1.175e-261 851.0
PYH2_k127_596508_20 Regulatory protein, FmdB family - - - 0.00001857 47.0
PYH2_k127_596508_21 small protein - - - 0.00003106 49.0
PYH2_k127_596508_3 Phosphofructokinase K00895 - 2.7.1.90 9.206e-215 681.0
PYH2_k127_596508_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 469.0
PYH2_k127_596508_5 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 356.0
PYH2_k127_596508_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
PYH2_k127_596508_7 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002716 289.0
PYH2_k127_596508_8 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002628 274.0
PYH2_k127_596508_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002148 267.0
PYH2_k127_6024668_0 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 8.694e-263 829.0
PYH2_k127_6024668_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000004311 235.0
PYH2_k127_6024668_2 Protein of unknown function (DUF3788) - - - 0.00000000000021 76.0
PYH2_k127_6029215_0 PFAM Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 534.0
PYH2_k127_6029215_1 Sulfite exporter TauE/SafE K07090 - - 0.000000005867 56.0
PYH2_k127_6049919_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 392.0
PYH2_k127_6049919_1 Transposase - - - 0.0000000000000000000000000000000000000007616 150.0
PYH2_k127_6049919_2 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000533 119.0
PYH2_k127_6052805_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000002344 59.0
PYH2_k127_6056805_0 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 599.0
PYH2_k127_6056805_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 606.0
PYH2_k127_6056805_10 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000002016 233.0
PYH2_k127_6056805_11 ThiF family - - - 0.000000000000000000000000000000000000000000000000000703 188.0
PYH2_k127_6056805_12 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000002771 190.0
PYH2_k127_6056805_13 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000007948 181.0
PYH2_k127_6056805_2 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 544.0
PYH2_k127_6056805_3 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 510.0
PYH2_k127_6056805_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 470.0
PYH2_k127_6056805_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 422.0
PYH2_k127_6056805_6 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 396.0
PYH2_k127_6056805_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 391.0
PYH2_k127_6056805_8 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 295.0
PYH2_k127_6056805_9 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002451 265.0
PYH2_k127_6150299_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 1.008e-256 809.0
PYH2_k127_6150299_1 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 373.0
PYH2_k127_6150299_2 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 270.0
PYH2_k127_6150299_3 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000005995 211.0
PYH2_k127_6150299_4 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000000000000001219 204.0
PYH2_k127_6150299_5 beta-mannosidase K01192 - 3.2.1.25 0.00000000000000000000000000000000001476 156.0
PYH2_k127_6150299_6 - - - - 0.0000000000000000000000005642 113.0
PYH2_k127_6150299_7 NlpC P60 family protein - - - 0.0000000001744 63.0
PYH2_k127_6150299_8 - - - - 0.00008835 48.0
PYH2_k127_6163966_0 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 383.0
PYH2_k127_6163966_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 309.0
PYH2_k127_6163966_2 Tannase and feruloyl esterase - - - 0.000000001309 62.0
PYH2_k127_6233931_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 374.0
PYH2_k127_6233931_1 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000002852 178.0
PYH2_k127_6233931_2 4Fe-4S binding domain protein K00123 - 1.17.1.9 0.0000000000000001454 90.0
PYH2_k127_6233931_3 coenzyme F420 hydrogenase activity K18007 - 1.12.1.2 0.000006013 48.0
PYH2_k127_6244339_0 metallocarboxypeptidase activity K14054 - - 0.0 1129.0
PYH2_k127_6244339_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 473.0
PYH2_k127_6244339_2 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 449.0
PYH2_k127_6244339_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 385.0
PYH2_k127_6244339_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000003593 228.0
PYH2_k127_6244339_5 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000005685 187.0
PYH2_k127_6244339_6 Peptidase, M16 K07263 - - 0.00000000000000000002236 102.0
PYH2_k127_6244339_7 Uracil-DNA glycosylase - - - 0.0000000000000006719 79.0
PYH2_k127_6261259_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 448.0
PYH2_k127_6261259_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000004067 64.0
PYH2_k127_6261259_2 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000001608 68.0
PYH2_k127_627646_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 454.0
PYH2_k127_627646_1 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000479 240.0
PYH2_k127_627646_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000001102 68.0
PYH2_k127_627646_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000582 64.0
PYH2_k127_6288375_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 470.0
PYH2_k127_6288375_1 - K07283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 331.0
PYH2_k127_6288375_2 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.00000000000000000000000000000005466 126.0
PYH2_k127_6288375_3 Hemerythrin HHE cation binding domain - - - 0.00006935 45.0
PYH2_k127_6297528_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1072.0
PYH2_k127_6297528_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.121e-287 910.0
PYH2_k127_6297528_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001144 228.0
PYH2_k127_6297528_11 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000341 205.0
PYH2_k127_6297528_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000001087 205.0
PYH2_k127_6297528_13 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000001049 176.0
PYH2_k127_6297528_14 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000006855 190.0
PYH2_k127_6297528_15 ATPase activity K01990 - - 0.000000000000000000000000000000000000000002719 159.0
PYH2_k127_6297528_16 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000003164 164.0
PYH2_k127_6297528_17 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000003729 155.0
PYH2_k127_6297528_18 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.0000000000004567 78.0
PYH2_k127_6297528_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 579.0
PYH2_k127_6297528_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 476.0
PYH2_k127_6297528_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 426.0
PYH2_k127_6297528_5 BNR repeat-like domain K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 422.0
PYH2_k127_6297528_6 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 377.0
PYH2_k127_6297528_7 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 315.0
PYH2_k127_6297528_8 LPPG Fo 2-phospho-L-lactate transferase K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 292.0
PYH2_k127_6297528_9 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002145 272.0
PYH2_k127_6302909_0 His Kinase A (phosphoacceptor - - - 9.918e-206 672.0
PYH2_k127_6302909_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 540.0
PYH2_k127_6302909_10 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000009861 182.0
PYH2_k127_6302909_11 Amidohydrolase K07045 - - 0.00000000000000000001211 103.0
PYH2_k127_6302909_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 483.0
PYH2_k127_6302909_3 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 420.0
PYH2_k127_6302909_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 333.0
PYH2_k127_6302909_5 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 331.0
PYH2_k127_6302909_6 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000005307 233.0
PYH2_k127_6302909_7 - - - - 0.00000000000000000000000000000000000000000000000000000001538 207.0
PYH2_k127_6302909_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000001491 189.0
PYH2_k127_6302909_9 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000004189 190.0
PYH2_k127_6302931_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 461.0
PYH2_k127_6302931_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000005583 158.0
PYH2_k127_6306747_0 Glycosyl hydrolase family 79, N-terminal domain - - - 2.445e-204 649.0
PYH2_k127_6306747_1 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003332 251.0
PYH2_k127_6306747_2 FtsX-like permease family - - - 0.000000000007391 72.0
PYH2_k127_6316013_0 acetoacetate decarboxylase K01574 - 4.1.1.4 0.00000000000000000000000000000000000000000003738 167.0
PYH2_k127_6316013_1 mRNA binding - - - 0.00000000000000006994 83.0
PYH2_k127_6316013_2 PFAM Uncharacterised protein family UPF0150 - - - 0.000006057 49.0
PYH2_k127_63187_0 peptidase activity K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000002074 175.0
PYH2_k127_63187_1 Peptidase family S41 - - - 0.0000000000000000000000001796 116.0
PYH2_k127_6376496_0 methyltransferase - - - 0.00000000000000000000000000000000000000000657 164.0
PYH2_k127_6376496_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000003856 122.0
PYH2_k127_6376496_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000006228 79.0
PYH2_k127_6424555_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.179e-273 863.0
PYH2_k127_6424555_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.808e-228 713.0
PYH2_k127_6424555_10 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000001066 228.0
PYH2_k127_6424555_11 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000003486 198.0
PYH2_k127_6424555_12 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000002966 190.0
PYH2_k127_6424555_13 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000002145 191.0
PYH2_k127_6424555_14 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000486 171.0
PYH2_k127_6424555_15 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000004762 112.0
PYH2_k127_6424555_16 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000001103 103.0
PYH2_k127_6424555_17 - - - - 0.000000000000079 81.0
PYH2_k127_6424555_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 578.0
PYH2_k127_6424555_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 524.0
PYH2_k127_6424555_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 516.0
PYH2_k127_6424555_5 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 327.0
PYH2_k127_6424555_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 304.0
PYH2_k127_6424555_7 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002839 279.0
PYH2_k127_6424555_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008411 272.0
PYH2_k127_6424555_9 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000001428 254.0
PYH2_k127_642521_0 ATPase BadF BadG BcrA BcrD type - - - 1.719e-295 940.0
PYH2_k127_642521_1 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.164e-269 845.0
PYH2_k127_642521_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 325.0
PYH2_k127_642521_11 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002054 286.0
PYH2_k127_642521_12 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001806 277.0
PYH2_k127_642521_13 protocatechuate 3,4-dioxygenase activity K03333 - 1.1.3.6 0.0000000000000000000000000000005127 142.0
PYH2_k127_642521_14 Calcineurin-like phosphoesterase - - - 0.00001926 56.0
PYH2_k127_642521_2 Dienelactone hydrolase family - - - 3.879e-241 762.0
PYH2_k127_642521_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 8.603e-194 608.0
PYH2_k127_642521_4 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 611.0
PYH2_k127_642521_5 Beta-xylanase K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 555.0
PYH2_k127_642521_6 PFAM Acetyl xylan esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 543.0
PYH2_k127_642521_7 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 383.0
PYH2_k127_642521_8 Glycosyl hydrolase family 20, domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 369.0
PYH2_k127_642521_9 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 322.0
PYH2_k127_6456235_0 FtsX-like permease family - - - 2.958e-208 689.0
PYH2_k127_6456235_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 554.0
PYH2_k127_6456235_10 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 321.0
PYH2_k127_6456235_11 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 312.0
PYH2_k127_6456235_12 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009707 250.0
PYH2_k127_6456235_13 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000001202 211.0
PYH2_k127_6456235_14 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.00000000000000000000000000000004296 132.0
PYH2_k127_6456235_2 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 573.0
PYH2_k127_6456235_3 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 479.0
PYH2_k127_6456235_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 469.0
PYH2_k127_6456235_5 von Willebrand factor type A domain K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 477.0
PYH2_k127_6456235_6 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 405.0
PYH2_k127_6456235_7 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 370.0
PYH2_k127_6456235_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 364.0
PYH2_k127_6456235_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 341.0
PYH2_k127_6469563_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 608.0
PYH2_k127_6469563_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 507.0
PYH2_k127_6469563_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 511.0
PYH2_k127_6469563_3 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 299.0
PYH2_k127_6469563_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
PYH2_k127_6548329_0 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 596.0
PYH2_k127_6548329_1 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 385.0
PYH2_k127_6548329_10 - - - - 0.0000000004122 62.0
PYH2_k127_6548329_11 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0002609 48.0
PYH2_k127_6548329_12 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0004495 50.0
PYH2_k127_6548329_2 chitin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 342.0
PYH2_k127_6548329_3 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003142 273.0
PYH2_k127_6548329_4 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
PYH2_k127_6548329_5 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000004919 178.0
PYH2_k127_6548329_6 COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.0000000000000000000000000000000000000000003691 179.0
PYH2_k127_6548329_7 HEPN domain - - - 0.00000000000000000000000000000000000002949 148.0
PYH2_k127_6548329_8 Nucleotidyltransferase domain - - - 0.00000000000004475 73.0
PYH2_k127_6548329_9 - - - - 0.00000000001052 66.0
PYH2_k127_6560128_0 GMC oxidoreductase - - - 3.404e-216 679.0
PYH2_k127_6560128_1 Predicted membrane protein (DUF2177) - - - 0.00000000000000000000000000000002249 129.0
PYH2_k127_6560128_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000001196 108.0
PYH2_k127_6568493_0 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 451.0
PYH2_k127_6568493_1 Tagatose 6 phosphate kinase K16371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 447.0
PYH2_k127_6568493_10 Acetamidase/Formamidase family K01426 - 3.5.1.4 0.00002545 50.0
PYH2_k127_6568493_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 429.0
PYH2_k127_6568493_3 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 347.0
PYH2_k127_6568493_4 isomerase K02082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 353.0
PYH2_k127_6568493_5 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 342.0
PYH2_k127_6568493_6 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 298.0
PYH2_k127_6568493_7 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000006116 259.0
PYH2_k127_6568493_8 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000004592 232.0
PYH2_k127_6568493_9 - - - - 0.000000000000000000000000000000000000000000000000006562 196.0
PYH2_k127_657223_0 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 9.556e-198 628.0
PYH2_k127_657223_1 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002781 250.0
PYH2_k127_657223_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000001654 78.0
PYH2_k127_6582021_0 Involved in the tonB-independent uptake of proteins K03641 - - 6.486e-209 666.0
PYH2_k127_6582021_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000001651 155.0
PYH2_k127_6596219_0 PFAM Nitroreductase - - - 0.00000000009264 71.0
PYH2_k127_6609453_0 family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 546.0
PYH2_k127_6609453_1 Domain of unknown function (DUF362) - - - 0.000000000003714 67.0
PYH2_k127_6612998_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 599.0
PYH2_k127_6612998_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 621.0
PYH2_k127_6612998_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000511 206.0
PYH2_k127_6612998_11 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000009668 192.0
PYH2_k127_6612998_12 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000000000000001708 170.0
PYH2_k127_6612998_13 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000143 160.0
PYH2_k127_6612998_14 - - - - 0.000000000000000000000000000000291 139.0
PYH2_k127_6612998_15 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000001762 127.0
PYH2_k127_6612998_16 Carboxypeptidase regulatory-like domain - - - 0.000000000000000002098 100.0
PYH2_k127_6612998_17 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000002977 89.0
PYH2_k127_6612998_18 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000006585 82.0
PYH2_k127_6612998_19 Tetratricopeptide repeat - - - 0.00000000001645 75.0
PYH2_k127_6612998_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 561.0
PYH2_k127_6612998_3 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 472.0
PYH2_k127_6612998_4 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 319.0
PYH2_k127_6612998_5 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 307.0
PYH2_k127_6612998_6 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004388 274.0
PYH2_k127_6612998_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
PYH2_k127_6612998_8 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000002693 242.0
PYH2_k127_6612998_9 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
PYH2_k127_6665044_0 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 419.0
PYH2_k127_6665044_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000009427 198.0
PYH2_k127_6665044_2 amine dehydrogenase activity K14647,K21449 - - 0.000000001094 71.0
PYH2_k127_6665044_3 Belongs to the 'phage' integrase family - - - 0.000786 45.0
PYH2_k127_6669590_0 formate dehydrogenase - - - 6.147e-233 740.0
PYH2_k127_6669590_1 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 499.0
PYH2_k127_6669590_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000011 144.0
PYH2_k127_6669590_3 Prokaryotic cytochrome b561 - - - 0.00000000001137 65.0
PYH2_k127_6669590_4 Putative zinc-finger - - - 0.00005491 54.0
PYH2_k127_6681601_0 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 510.0
PYH2_k127_6681601_1 phosphorelay signal transduction system K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 374.0
PYH2_k127_6681601_2 signal transduction protein containing EAL and modified HD-GYP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
PYH2_k127_6681601_3 NIPSNAP family containing protein - - - 0.0000000000000000000000000000000000000000000488 164.0
PYH2_k127_6681601_4 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000001336 156.0
PYH2_k127_6681601_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000005628 76.0
PYH2_k127_6702058_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 586.0
PYH2_k127_6702058_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 396.0
PYH2_k127_6702058_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000005224 201.0
PYH2_k127_6702058_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000002547 190.0
PYH2_k127_6702058_12 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000002301 187.0
PYH2_k127_6702058_13 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000001704 186.0
PYH2_k127_6702058_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000001513 173.0
PYH2_k127_6702058_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000001999 164.0
PYH2_k127_6702058_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000218 160.0
PYH2_k127_6702058_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000003702 162.0
PYH2_k127_6702058_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000463 139.0
PYH2_k127_6702058_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000006855 130.0
PYH2_k127_6702058_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 320.0
PYH2_k127_6702058_20 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000009994 132.0
PYH2_k127_6702058_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000007992 119.0
PYH2_k127_6702058_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001634 113.0
PYH2_k127_6702058_23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000002545 117.0
PYH2_k127_6702058_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008417 96.0
PYH2_k127_6702058_25 Ribosomal protein L30 K02907 - - 0.0000000000000000007539 88.0
PYH2_k127_6702058_26 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000002624 69.0
PYH2_k127_6702058_27 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001318 67.0
PYH2_k127_6702058_28 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001631 66.0
PYH2_k127_6702058_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002086 281.0
PYH2_k127_6702058_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000943 274.0
PYH2_k127_6702058_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000005666 237.0
PYH2_k127_6702058_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000003631 230.0
PYH2_k127_6702058_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
PYH2_k127_6702058_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000001419 227.0
PYH2_k127_6702058_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000007303 226.0
PYH2_k127_6715487_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002577 251.0
PYH2_k127_6715487_1 DNA-directed DNA polymerase activity - - - 0.000000000000003932 89.0
PYH2_k127_6715487_2 - - - - 0.00000918 54.0
PYH2_k127_6715487_3 Belongs to the glycosyl hydrolase 18 family - - - 0.0006291 53.0
PYH2_k127_674196_0 Protein of unknown function (DUF1553) - - - 1.402e-310 984.0
PYH2_k127_674196_1 Protein of unknown function (DUF1501) - - - 3.765e-222 696.0
PYH2_k127_674196_10 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 388.0
PYH2_k127_674196_11 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 349.0
PYH2_k127_674196_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 342.0
PYH2_k127_674196_13 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000002899 160.0
PYH2_k127_674196_14 Endoribonuclease L-PSP - - - 0.0000000000000000001185 104.0
PYH2_k127_674196_15 Endoribonuclease L-PSP K09022 GO:0001505,GO:0001655,GO:0001822,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005829,GO:0006082,GO:0006139,GO:0006417,GO:0006457,GO:0006520,GO:0006544,GO:0006566,GO:0006567,GO:0006725,GO:0006807,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008285,GO:0008289,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016054,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017144,GO:0017148,GO:0019222,GO:0019239,GO:0019518,GO:0019752,GO:0022402,GO:0030323,GO:0030324,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031974,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0033293,GO:0033993,GO:0034248,GO:0034249,GO:0034641,GO:0035295,GO:0036041,GO:0036094,GO:0042127,GO:0042133,GO:0042221,GO:0042579,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048513,GO:0048519,GO:0048523,GO:0048731,GO:0048856,GO:0050678,GO:0050680,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0060322,GO:0060541,GO:0065007,GO:0065008,GO:0070013,GO:0070314,GO:0071704,GO:0072001,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902074,GO:1904012,GO:1904013,GO:2000112,GO:2000113 3.5.99.10 0.00000000003258 77.0
PYH2_k127_674196_16 endoribonuclease L-PSP K06927,K15067 - 3.5.99.5,6.3.1.14 0.00000000274 70.0
PYH2_k127_674196_2 peptidase M20 - - - 2.52e-218 685.0
PYH2_k127_674196_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 519.0
PYH2_k127_674196_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 431.0
PYH2_k127_674196_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 439.0
PYH2_k127_674196_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 423.0
PYH2_k127_674196_7 PFAM aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 413.0
PYH2_k127_674196_8 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 399.0
PYH2_k127_674196_9 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 394.0
PYH2_k127_6768722_0 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000000000000000000008778 214.0
PYH2_k127_6768722_2 Nucleotidyltransferase domain - - - 0.0000000000000000002211 94.0
PYH2_k127_6797347_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 313.0
PYH2_k127_6799826_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.577e-249 781.0
PYH2_k127_6799826_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.088e-244 784.0
PYH2_k127_6799826_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 398.0
PYH2_k127_6799826_11 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 402.0
PYH2_k127_6799826_12 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 380.0
PYH2_k127_6799826_13 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 358.0
PYH2_k127_6799826_14 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 349.0
PYH2_k127_6799826_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 351.0
PYH2_k127_6799826_16 PFAM Cation transporter K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 356.0
PYH2_k127_6799826_17 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 346.0
PYH2_k127_6799826_18 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 354.0
PYH2_k127_6799826_19 SMART band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 332.0
PYH2_k127_6799826_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.056e-195 623.0
PYH2_k127_6799826_20 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
PYH2_k127_6799826_21 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 312.0
PYH2_k127_6799826_22 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
PYH2_k127_6799826_23 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 310.0
PYH2_k127_6799826_24 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008156 287.0
PYH2_k127_6799826_25 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
PYH2_k127_6799826_26 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000457 279.0
PYH2_k127_6799826_27 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001256 269.0
PYH2_k127_6799826_28 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009435 279.0
PYH2_k127_6799826_29 cation efflux K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001294 265.0
PYH2_k127_6799826_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 539.0
PYH2_k127_6799826_30 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000003922 238.0
PYH2_k127_6799826_31 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000000000000000000001473 234.0
PYH2_k127_6799826_32 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000211 222.0
PYH2_k127_6799826_33 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000001706 214.0
PYH2_k127_6799826_34 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000005776 206.0
PYH2_k127_6799826_35 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000006367 224.0
PYH2_k127_6799826_36 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000001254 197.0
PYH2_k127_6799826_37 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000005754 195.0
PYH2_k127_6799826_38 Potassium uptake system protein K03499 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000001925 190.0
PYH2_k127_6799826_39 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.000000000000000000000000000000001036 134.0
PYH2_k127_6799826_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 496.0
PYH2_k127_6799826_40 lipopolysaccharide transport K09774 - - 0.000000000000000000000001815 121.0
PYH2_k127_6799826_41 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000002599 100.0
PYH2_k127_6799826_42 - - - - 0.000000000000000000003896 101.0
PYH2_k127_6799826_43 Phosphotransferase System K11189 - - 0.00000000000000000001405 94.0
PYH2_k127_6799826_45 Bacterial transcriptional repressor C-terminal - - - 0.00000000007709 66.0
PYH2_k127_6799826_46 - - - - 0.0000000001283 66.0
PYH2_k127_6799826_47 Evidence 4 Homologs of previously reported genes of - - - 0.000000000369 72.0
PYH2_k127_6799826_48 Predicted membrane protein (DUF2085) - - - 0.000000000424 67.0
PYH2_k127_6799826_49 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00000001415 57.0
PYH2_k127_6799826_5 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 472.0
PYH2_k127_6799826_50 - - - - 0.0000004035 58.0
PYH2_k127_6799826_51 - - - - 0.000004376 52.0
PYH2_k127_6799826_52 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000008735 54.0
PYH2_k127_6799826_53 Protein of unknown function (DUF3108) - - - 0.00002284 55.0
PYH2_k127_6799826_54 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0002928 51.0
PYH2_k127_6799826_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 480.0
PYH2_k127_6799826_7 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 426.0
PYH2_k127_6799826_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 422.0
PYH2_k127_6799826_9 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 397.0
PYH2_k127_6828536_0 - K01154,K03427,K09388 - 2.1.1.72,3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 486.0
PYH2_k127_6828536_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
PYH2_k127_6828536_2 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000003339 186.0
PYH2_k127_6828536_3 - - - - 0.0000000000000000000000000003201 124.0
PYH2_k127_6828536_5 Domain of unknown function (DUF4433) - - - 0.0000000000000000000597 93.0
PYH2_k127_6828536_6 Protein of unknown function DUF86 - - - 0.0000000000000002551 89.0
PYH2_k127_6828536_7 Nucleotidyltransferase domain - - - 0.0000006745 57.0
PYH2_k127_6828536_8 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0007342 50.0
PYH2_k127_6829844_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 305.0
PYH2_k127_6829844_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00002929 49.0
PYH2_k127_6837373_0 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000001819 231.0
PYH2_k127_6837373_1 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002195 217.0
PYH2_k127_6837373_2 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000431 201.0
PYH2_k127_6842135_0 AcrB/AcrD/AcrF family K11326 - - 0.0 1316.0
PYH2_k127_6842135_1 pyrroloquinoline quinone binding - - - 2.755e-202 659.0
PYH2_k127_6842135_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 306.0
PYH2_k127_6842135_3 YCII-related domain K09780 - - 0.0000000000000000000000000004388 124.0
PYH2_k127_6842135_4 PFAM DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.000000000008598 71.0
PYH2_k127_6842135_5 PIN domain - - - 0.000000008064 61.0
PYH2_k127_6846870_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001412 220.0
PYH2_k127_6846870_1 - - - - 0.0000000000000000000000000000000000000000000000000001242 201.0
PYH2_k127_6846870_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000002124 169.0
PYH2_k127_6902460_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 1.458e-269 841.0
PYH2_k127_6902460_1 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002989 260.0
PYH2_k127_6902460_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003969 228.0
PYH2_k127_6902460_3 Fic/DOC family K04095 - - 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
PYH2_k127_6910005_0 Amidohydrolase family - - - 1.271e-252 792.0
PYH2_k127_6910005_1 Protein of unknown function (DUF4038) - - - 4.458e-220 689.0
PYH2_k127_6910005_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000002019 124.0
PYH2_k127_6910005_3 TonB-dependent receptor - - - 0.00000008111 53.0
PYH2_k127_693797_0 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000559 293.0
PYH2_k127_6957736_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 530.0
PYH2_k127_6957736_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 370.0
PYH2_k127_6957736_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000003789 109.0
PYH2_k127_6957736_3 PBS lyase - - - 0.0000000002349 73.0
PYH2_k127_6957736_4 Bacterial transcriptional activator domain - - - 0.00003807 55.0
PYH2_k127_7042912_0 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 353.0
PYH2_k127_7042912_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008583 291.0
PYH2_k127_7042912_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000009081 206.0
PYH2_k127_7042912_3 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000002014 148.0
PYH2_k127_7042912_4 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000003776 156.0
PYH2_k127_7042912_5 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000002376 81.0
PYH2_k127_7042912_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000007859 65.0
PYH2_k127_7042912_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000004154 56.0
PYH2_k127_7047862_0 - - - - 2.326e-307 954.0
PYH2_k127_7047862_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K05587 - 1.6.5.3 3.73e-224 708.0
PYH2_k127_7047862_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 574.0
PYH2_k127_7047862_3 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 343.0
PYH2_k127_7047862_4 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000009072 224.0
PYH2_k127_7047862_5 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000112 213.0
PYH2_k127_7047862_6 Coenzyme F420-reducing hydrogenase, gamma subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000287 207.0
PYH2_k127_7047862_7 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K05586 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000005717 188.0
PYH2_k127_7047862_8 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000008313 160.0
PYH2_k127_7051833_0 DNA polymerase type-B family K02336 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 564.0
PYH2_k127_7051833_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 551.0
PYH2_k127_7051833_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000003999 210.0
PYH2_k127_7051833_3 oxidoreductase activity - - - 0.0000008108 58.0
PYH2_k127_7071912_0 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 304.0
PYH2_k127_7076076_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 429.0
PYH2_k127_7076076_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 414.0
PYH2_k127_7076076_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 362.0
PYH2_k127_7076076_3 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 301.0
PYH2_k127_7076076_4 transposition K03561,K07497 - - 0.000001232 53.0
PYH2_k127_7097812_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 439.0
PYH2_k127_7097812_1 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 336.0
PYH2_k127_7097812_10 Tetratricopeptide repeat protein - GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023 - 0.00000004069 65.0
PYH2_k127_7097812_11 Putative adhesin - - - 0.000006103 57.0
PYH2_k127_7097812_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 330.0
PYH2_k127_7097812_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000009369 214.0
PYH2_k127_7097812_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001732 203.0
PYH2_k127_7097812_5 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000001032 170.0
PYH2_k127_7097812_6 Ferredoxin K00523,K00529,K02639,K04755,K05784,K07140,K08952,K08953,K08954,K11107,K11311,K14581,K15753,K15765,K16161,K16246,K18077,K18225,K18293 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0019748,GO:0032991,GO:0042221,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043446,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046858,GO:0050896,GO:0055114,GO:0071704,GO:0098754,GO:1902494 1.14.13.25,1.17.1.1,1.18.1.3,1.18.1.7 0.0000000000000000000000006227 111.0
PYH2_k127_7097812_7 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000005928 98.0
PYH2_k127_7097812_8 PFAM Phosphoglycerate mutase - - - 0.000000000000000247 85.0
PYH2_k127_7116980_0 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 452.0
PYH2_k127_7173838_0 RNA secondary structure unwinding K03724 - - 0.0 1449.0
PYH2_k127_7173838_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 481.0
PYH2_k127_7173838_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03830 - - 0.000000001872 64.0
PYH2_k127_7173838_2 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 409.0
PYH2_k127_7173838_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 384.0
PYH2_k127_7173838_4 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 336.0
PYH2_k127_7173838_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 321.0
PYH2_k127_7173838_6 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000003351 185.0
PYH2_k127_7173838_7 - - - - 0.0000000000000000000000000000000002898 138.0
PYH2_k127_7173838_8 methyltransferase K21459 - 2.1.1.301 0.0000000000000000000000000000000008649 142.0
PYH2_k127_7173838_9 Thiol-disulfide isomerase and - - - 0.0000000000000000000000000000788 122.0
PYH2_k127_7246207_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.206e-213 676.0
PYH2_k127_7246207_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 345.0
PYH2_k127_7246207_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 304.0
PYH2_k127_7246207_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000005362 233.0
PYH2_k127_7246207_4 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000003845 184.0
PYH2_k127_7266588_0 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 413.0
PYH2_k127_7266588_1 TIGRFAM TIGR02453 family protein - - - 0.000000000000000000000000000000000000000000000000000003845 201.0
PYH2_k127_7266588_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000001078 164.0
PYH2_k127_7266588_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K21328 - 2.6.1.33 0.000000000000000001296 87.0
PYH2_k127_7266588_4 Belongs to the glycosyl hydrolase 35 family - - - 0.0000000004557 72.0
PYH2_k127_7266588_5 Integrase, catalytic region K07497 - - 0.000000002175 61.0
PYH2_k127_7266588_6 - - - - 0.00008235 46.0
PYH2_k127_7278093_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 415.0
PYH2_k127_7278093_1 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 313.0
PYH2_k127_7278093_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 308.0
PYH2_k127_7278093_3 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009319 272.0
PYH2_k127_7278093_4 - - - - 0.0000000000000000000000000000000004672 143.0
PYH2_k127_7278093_5 - - - - 0.0002366 51.0
PYH2_k127_7319276_0 extracellular alpha-helical protein K06894 - - 0.0 1887.0
PYH2_k127_7319276_1 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 0.0 1025.0
PYH2_k127_7319276_10 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 301.0
PYH2_k127_7319276_11 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003814 273.0
PYH2_k127_7319276_12 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000008965 240.0
PYH2_k127_7319276_13 alcohol dehydrogenase K08322 - 1.1.1.380 0.00000000000000000000000000000000000000000000000000000000000000009376 235.0
PYH2_k127_7319276_14 G3E family - - - 0.0000000000000000000000000000000000000000000000000004665 195.0
PYH2_k127_7319276_15 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000653 165.0
PYH2_k127_7319276_2 Domain of unknown function (DUF5127) - - - 4.607e-271 851.0
PYH2_k127_7319276_3 COG0464 ATPases of the AAA class - - - 2.858e-195 625.0
PYH2_k127_7319276_4 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 626.0
PYH2_k127_7319276_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 527.0
PYH2_k127_7319276_6 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 524.0
PYH2_k127_7319276_7 Aldo Keto reductase K17744 - 1.1.1.316 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 444.0
PYH2_k127_7319276_8 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 437.0
PYH2_k127_7319276_9 signal transduction protein containing EAL and modified HD-GYP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 372.0
PYH2_k127_7346356_0 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 409.0
PYH2_k127_7346356_1 Ferredoxin - - - 0.000000000000000000000000000000000001045 141.0
PYH2_k127_7346356_2 Acetyltransferase (GNAT) family - - - 0.000000002898 66.0
PYH2_k127_734871_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1075.0
PYH2_k127_734871_1 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 531.0
PYH2_k127_734871_10 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000178 193.0
PYH2_k127_734871_11 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000007924 160.0
PYH2_k127_734871_12 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000003918 160.0
PYH2_k127_734871_13 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000154 155.0
PYH2_k127_734871_14 exporters of the RND superfamily K07003 - - 0.000000000000000000000000002349 113.0
PYH2_k127_734871_15 pseudaminic acid biosynthesis-associated protein PseG K15897 - 3.6.1.57 0.00000000000000002714 94.0
PYH2_k127_734871_16 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000001204 82.0
PYH2_k127_734871_17 Flagellar FlbD family protein K02385 - - 0.00000000007309 68.0
PYH2_k127_734871_18 Tetratricopeptide repeat - - - 0.000000006517 68.0
PYH2_k127_734871_19 YacP-like NYN domain K06962 - - 0.00000008147 61.0
PYH2_k127_734871_2 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 335.0
PYH2_k127_734871_20 - - - - 0.00001987 55.0
PYH2_k127_734871_21 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0003365 45.0
PYH2_k127_734871_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
PYH2_k127_734871_4 PFAM Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 271.0
PYH2_k127_734871_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002539 273.0
PYH2_k127_734871_6 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000004279 216.0
PYH2_k127_734871_7 Protein of unknown function DUF115 - - - 0.00000000000000000000000000000000000000000000000000000006295 218.0
PYH2_k127_734871_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000007495 203.0
PYH2_k127_734871_9 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000003676 202.0
PYH2_k127_7398678_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 592.0
PYH2_k127_7398678_1 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000002426 126.0
PYH2_k127_742223_0 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000001992 178.0
PYH2_k127_742223_1 GYD domain - - - 0.000000000000000000000000000000000006214 138.0
PYH2_k127_742223_2 NmrA-like family - - - 0.00006513 47.0
PYH2_k127_7424229_0 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008049 294.0
PYH2_k127_7424229_1 carbon-oxygen lyase activity, acting on polysaccharides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006281 268.0
PYH2_k127_7424229_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000001769 253.0
PYH2_k127_7424229_3 - - - - 0.00000000000000000008133 98.0
PYH2_k127_7424229_4 SpoIIAA-like - - - 0.0000000000000003944 83.0
PYH2_k127_7424229_5 - - - - 0.00000000493 66.0
PYH2_k127_7501709_0 Site-specific recombinase, DNA invertase Pin - - - 4.189e-230 736.0
PYH2_k127_7501709_2 Integrase - - - 0.000000000005376 66.0
PYH2_k127_7502814_0 PFAM Integrase catalytic - - - 9.081e-206 653.0
PYH2_k127_7502814_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 559.0
PYH2_k127_7502814_2 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 336.0
PYH2_k127_7538654_0 trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000932 209.0
PYH2_k127_7538654_1 - - - - 0.000000000000000000000000000000007405 132.0
PYH2_k127_7538654_2 InterPro IPR007367 - - - 0.0000000000000000000331 94.0
PYH2_k127_7538654_3 Bacterial pre-peptidase C-terminal domain - - - 0.0000000000000008024 86.0
PYH2_k127_7538654_4 Glycosyl hydrolase family 9 - - - 0.0000000000113 68.0
PYH2_k127_7538654_5 amine dehydrogenase activity - - - 0.0000000009462 68.0
PYH2_k127_7544590_0 response regulator, receiver K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 479.0
PYH2_k127_7544590_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000003504 223.0
PYH2_k127_7595818_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 4.375e-205 658.0
PYH2_k127_7595818_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 2.795e-203 642.0
PYH2_k127_7595818_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000009033 172.0
PYH2_k127_7595818_11 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000003452 161.0
PYH2_k127_7595818_12 dephospho-CoA kinase activity - - - 0.000000000000000000000000000000000001971 151.0
PYH2_k127_7595818_13 CYTH K05873 - 4.6.1.1 0.000000000000000000000000000000001283 138.0
PYH2_k127_7595818_14 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000159 137.0
PYH2_k127_7595818_15 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000004814 134.0
PYH2_k127_7595818_16 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000003396 124.0
PYH2_k127_7595818_17 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000002269 66.0
PYH2_k127_7595818_18 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000007703 57.0
PYH2_k127_7595818_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 452.0
PYH2_k127_7595818_3 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 365.0
PYH2_k127_7595818_4 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 312.0
PYH2_k127_7595818_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001471 249.0
PYH2_k127_7595818_6 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000005025 224.0
PYH2_k127_7595818_7 dCMP deaminase activity K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000112 211.0
PYH2_k127_7595818_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000001366 208.0
PYH2_k127_7595818_9 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000001408 181.0
PYH2_k127_7620980_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 479.0
PYH2_k127_7620980_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 357.0
PYH2_k127_7620980_2 response regulator - - - 0.00000000000000000000000000000000000000000000000421 180.0
PYH2_k127_7620980_3 COG0500 SAM-dependent methyltransferases - - - 0.0001952 52.0
PYH2_k127_7622505_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001685 259.0
PYH2_k127_7638058_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 594.0
PYH2_k127_7640873_0 SMART metal-dependent phosphohydrolase, HD K06885 - - 0.0000000000000000000000000000000000000000000000000000000000003149 228.0
PYH2_k127_7641364_0 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 315.0
PYH2_k127_7658679_0 PFAM Radical SAM - - - 2.034e-224 706.0
PYH2_k127_7658679_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007817 257.0
PYH2_k127_7658679_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008129 258.0
PYH2_k127_7658679_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000007476 129.0
PYH2_k127_7658679_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000001458 104.0
PYH2_k127_7660783_0 NADH-quinone oxidoreductase subunit F K18005 - 1.12.1.2 1.491e-213 678.0
PYH2_k127_7660783_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 6.965e-209 668.0
PYH2_k127_7660783_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000001171 125.0
PYH2_k127_7660783_11 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000007845 123.0
PYH2_k127_7660783_12 cheY-homologous receiver domain - - - 0.0000000001229 67.0
PYH2_k127_7660783_13 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000002 52.0
PYH2_k127_7660783_2 hydrogenase large subunit K00436 - 1.12.1.2 3.182e-205 649.0
PYH2_k127_7660783_3 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 617.0
PYH2_k127_7660783_4 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 338.0
PYH2_k127_7660783_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 327.0
PYH2_k127_7660783_6 NADH ubiquinone oxidoreductase K18006,K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001337 278.0
PYH2_k127_7660783_7 Coenzyme F420-reducing hydrogenase, gamma subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000102 265.0
PYH2_k127_7660783_8 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000002781 230.0
PYH2_k127_7660783_9 GAF domain - - - 0.00000000000000000000000000000000009811 153.0
PYH2_k127_7687591_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 600.0
PYH2_k127_7695502_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.013e-260 812.0
PYH2_k127_7695502_1 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 1.097e-238 744.0
PYH2_k127_7695502_2 Belongs to the fatty acid desaturase type 1 family K20416 GO:0000038,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016053,GO:0016491,GO:0019752,GO:0031984,GO:0032787,GO:0033559,GO:0042175,GO:0042761,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0072330,GO:0098827,GO:1901576 1.14.19.42 0.0000000000000000000000000000000000000000006066 170.0
PYH2_k127_7695502_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000006682 142.0
PYH2_k127_7728487_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1090.0
PYH2_k127_7728487_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 1.323e-304 942.0
PYH2_k127_7728487_10 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000673 225.0
PYH2_k127_7728487_11 Halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000512 227.0
PYH2_k127_7728487_12 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000001505 198.0
PYH2_k127_7728487_13 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000003235 161.0
PYH2_k127_7728487_14 PFAM Anion-transporting ATPase - - - 0.0000000000000000000000000000000000000003648 168.0
PYH2_k127_7728487_15 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000006444 147.0
PYH2_k127_7728487_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000002789 114.0
PYH2_k127_7728487_17 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000001726 118.0
PYH2_k127_7728487_18 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000009235 109.0
PYH2_k127_7728487_19 Thioredoxin K03671 - - 0.0000000000000000000001999 102.0
PYH2_k127_7728487_2 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 1.474e-283 882.0
PYH2_k127_7728487_20 - - - - 0.0000000000000000006623 98.0
PYH2_k127_7728487_3 PIN domain K07175 - - 1.163e-213 672.0
PYH2_k127_7728487_4 Glycosyl Hydrolase Family 88 - - - 1.576e-194 620.0
PYH2_k127_7728487_5 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 599.0
PYH2_k127_7728487_6 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 506.0
PYH2_k127_7728487_7 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 336.0
PYH2_k127_7728487_8 bond formation protein DsbB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 319.0
PYH2_k127_7728487_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001072 272.0
PYH2_k127_7738864_0 GMC oxidoreductase - - - 3.015e-266 829.0
PYH2_k127_7738864_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 533.0
PYH2_k127_7738864_2 Belongs to the IlvD Edd family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 444.0
PYH2_k127_7738864_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 329.0
PYH2_k127_7738864_4 - - - - 0.000000000000000000000000000000000000000000000000151 181.0
PYH2_k127_7743517_0 PFAM type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1270.0
PYH2_k127_7743517_1 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 323.0
PYH2_k127_7743517_2 - - - - 0.00000000000000000000000000274 117.0
PYH2_k127_7743517_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000001919 111.0
PYH2_k127_7746924_0 carboxylic acid catabolic process K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 520.0
PYH2_k127_7746924_1 HET domain-containing protein - - - 0.0000000000002817 79.0
PYH2_k127_7746924_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000001436 59.0
PYH2_k127_7784071_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 434.0
PYH2_k127_7812491_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.486e-308 958.0
PYH2_k127_7812491_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 6.335e-278 864.0
PYH2_k127_7812491_10 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 501.0
PYH2_k127_7812491_11 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 350.0
PYH2_k127_7812491_12 alanine dehydrogenase activity K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 350.0
PYH2_k127_7812491_13 oxidoreductase activity, acting on diphenols and related substances as donors K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001993 270.0
PYH2_k127_7812491_14 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000003885 244.0
PYH2_k127_7812491_15 Biogenesis protein K09792 - - 0.0000000000000000000000000000000000000000000001363 183.0
PYH2_k127_7812491_17 Zincin-like metallopeptidase - - - 0.000000000000000000000002778 106.0
PYH2_k127_7812491_2 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 9.038e-261 828.0
PYH2_k127_7812491_3 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 6.762e-257 801.0
PYH2_k127_7812491_4 Succinyl-CoA ligase like flavodoxin domain - - - 4.378e-238 766.0
PYH2_k127_7812491_5 PFAM amidohydrolase - - - 7.044e-225 709.0
PYH2_k127_7812491_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 2.395e-219 694.0
PYH2_k127_7812491_7 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 614.0
PYH2_k127_7812491_8 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 563.0
PYH2_k127_7812491_9 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 527.0
PYH2_k127_7852368_0 Domain of unknown function (DUF5117) - - - 3.404e-309 962.0
PYH2_k127_7852368_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.954e-204 647.0
PYH2_k127_7852368_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
PYH2_k127_7852368_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 430.0
PYH2_k127_7852368_4 Conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 368.0
PYH2_k127_7852368_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 350.0
PYH2_k127_7852368_6 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 333.0
PYH2_k127_7852368_7 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000007916 233.0
PYH2_k127_7852368_8 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
PYH2_k127_7855749_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 569.0
PYH2_k127_7855749_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 540.0
PYH2_k127_7855749_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000002299 121.0
PYH2_k127_7855749_11 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000001421 116.0
PYH2_k127_7855749_12 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000003757 87.0
PYH2_k127_7855749_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000001346 80.0
PYH2_k127_7855749_14 COG1450 Type II secretory pathway, component PulD K02453 - - 0.000000000007246 67.0
PYH2_k127_7855749_2 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 398.0
PYH2_k127_7855749_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 371.0
PYH2_k127_7855749_4 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 340.0
PYH2_k127_7855749_5 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 316.0
PYH2_k127_7855749_6 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000001375 241.0
PYH2_k127_7855749_7 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000001216 226.0
PYH2_k127_7855749_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000003611 159.0
PYH2_k127_7855749_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000003511 145.0
PYH2_k127_7867998_0 Psort location Cytoplasmic, score 8.87 K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 412.0
PYH2_k127_7867998_1 acetylesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 356.0
PYH2_k127_7895731_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 513.0
PYH2_k127_7895731_1 - - - - 0.0000000000000000000000000000000000000008661 149.0
PYH2_k127_7895731_2 beta-propeller repeat - - - 0.00000000000000000000000003671 113.0
PYH2_k127_7910395_0 COG4584 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 441.0
PYH2_k127_7910395_1 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 316.0
PYH2_k127_7910395_2 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.0000000000000000000000001865 107.0
PYH2_k127_7910395_4 - - - - 0.000000001683 65.0
PYH2_k127_7921009_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.47e-295 926.0
PYH2_k127_7921009_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.729e-195 614.0
PYH2_k127_7921009_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 479.0
PYH2_k127_7921009_3 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006636 257.0
PYH2_k127_7921009_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000006641 187.0
PYH2_k127_7921009_5 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000278 187.0
PYH2_k127_7921009_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000001273 171.0
PYH2_k127_7921009_7 peptide catabolic process - - - 0.000000000000003782 75.0
PYH2_k127_7931451_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 453.0
PYH2_k127_7931451_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 424.0
PYH2_k127_7931451_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000002436 190.0
PYH2_k127_7931451_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000689 128.0
PYH2_k127_7931451_4 Putative adhesin - - - 0.000000000000000000000000002689 122.0
PYH2_k127_7931451_5 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000004331 72.0
PYH2_k127_7931451_6 cyclic nucleotide-binding - - - 0.000001509 54.0
PYH2_k127_7941210_0 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 373.0
PYH2_k127_7941210_1 Urea ABC transporter permease K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 364.0
PYH2_k127_7969332_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 486.0
PYH2_k127_7969332_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000001913 187.0
PYH2_k127_7969332_2 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000000007577 179.0
PYH2_k127_7969332_3 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.00000000000000000000000000000000000000000000009361 178.0
PYH2_k127_7983547_0 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 260.0
PYH2_k127_7983547_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000004321 186.0
PYH2_k127_7983547_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000007905 162.0
PYH2_k127_7983547_3 Fibronectin type 3 domain - - - 0.0000000000004295 83.0
PYH2_k127_8045_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.938e-301 939.0
PYH2_k127_8045_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.281e-238 757.0
PYH2_k127_8045_10 Domain of unknown function (DUF4340) - - - 0.000000003393 69.0
PYH2_k127_8045_2 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 548.0
PYH2_k127_8045_3 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 447.0
PYH2_k127_8045_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 367.0
PYH2_k127_8045_5 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 360.0
PYH2_k127_8045_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 321.0
PYH2_k127_8045_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000009299 222.0
PYH2_k127_8045_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000001983 136.0
PYH2_k127_8045_9 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000002912 115.0
PYH2_k127_8075161_0 TonB-dependent receptor K13735,K20276 - - 2.071e-258 835.0
PYH2_k127_8075161_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 379.0
PYH2_k127_8075161_2 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003689 279.0
PYH2_k127_8075161_3 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000001512 244.0
PYH2_k127_8075161_4 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006191 229.0
PYH2_k127_8075161_5 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000009174 192.0
PYH2_k127_8075161_6 alpha-L-rhamnosidase - - - 0.000008774 50.0
PYH2_k127_8097265_0 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000276 275.0
PYH2_k127_8097265_1 polysaccharide export K01991 - - 0.0000000004044 68.0
PYH2_k127_8186330_0 Protein of unknown function, DUF255 K06888 - - 1.263e-250 791.0
PYH2_k127_8186330_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 379.0
PYH2_k127_8186330_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000003156 105.0
PYH2_k127_8186330_3 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.000006097 50.0
PYH2_k127_8201211_0 PFAM Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 387.0
PYH2_k127_8201211_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000009324 87.0
PYH2_k127_8219159_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 559.0
PYH2_k127_8219159_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 477.0
PYH2_k127_8219159_2 Domain of unknown function (DUF5107) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 332.0
PYH2_k127_8219159_3 myo-inosose-2 dehydratase activity K21909 - 5.1.3.38 0.000001281 59.0
PYH2_k127_8271790_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 545.0
PYH2_k127_8271790_1 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 523.0
PYH2_k127_8271790_10 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 270.0
PYH2_k127_8271790_11 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000005383 249.0
PYH2_k127_8271790_12 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001327 232.0
PYH2_k127_8271790_13 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000007179 192.0
PYH2_k127_8271790_14 Rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000001969 168.0
PYH2_k127_8271790_15 Helix-hairpin-helix motif - - - 0.000000000000000000000003352 106.0
PYH2_k127_8271790_16 Cytidylate kinase-like family - - - 0.00000000000000000000005608 108.0
PYH2_k127_8271790_17 Domain of unknown function (DUF1844) - - - 0.00000000000000000138 94.0
PYH2_k127_8271790_18 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000001526 77.0
PYH2_k127_8271790_19 - - - - 0.000000005147 64.0
PYH2_k127_8271790_2 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 534.0
PYH2_k127_8271790_20 shape-determining protein MreD K03571 - - 0.00000107 57.0
PYH2_k127_8271790_3 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 477.0
PYH2_k127_8271790_4 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 477.0
PYH2_k127_8271790_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
PYH2_k127_8271790_6 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
PYH2_k127_8271790_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
PYH2_k127_8271790_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
PYH2_k127_8271790_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000888 270.0
PYH2_k127_8273873_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 522.0
PYH2_k127_828745_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 476.0
PYH2_k127_828745_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 432.0
PYH2_k127_828745_10 PFAM HDOD domain - - - 0.00000000000000000000000000002412 128.0
PYH2_k127_828745_11 Chemotaxis phosphatase CheX - - - 0.00000000000000000003992 98.0
PYH2_k127_828745_12 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000005805 84.0
PYH2_k127_828745_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 384.0
PYH2_k127_828745_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007402 284.0
PYH2_k127_828745_4 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001412 262.0
PYH2_k127_828745_5 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000002081 183.0
PYH2_k127_828745_6 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000002716 181.0
PYH2_k127_828745_7 PFAM response regulator receiver K02488,K02658,K03413 - 2.7.7.65 0.0000000000000000000000000000000000000000006996 174.0
PYH2_k127_828745_8 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000006614 162.0
PYH2_k127_828745_9 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000001269 167.0
PYH2_k127_8413801_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.812e-293 940.0
PYH2_k127_8413801_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331 - 1.12.1.3,1.6.5.3 1.198e-239 753.0
PYH2_k127_8413801_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 5.464e-221 719.0
PYH2_k127_8413801_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 441.0
PYH2_k127_8413801_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 316.0
PYH2_k127_8413801_5 FMN-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003233 273.0
PYH2_k127_8413801_6 cheY-homologous receiver domain K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000003172 232.0
PYH2_k127_8413801_7 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004233 196.0
PYH2_k127_8413801_8 - K03616 - - 0.0000000000000000000000000000000000004122 147.0
PYH2_k127_8413801_9 amine dehydrogenase activity - - - 0.000000000000000000000000000006355 132.0
PYH2_k127_8445395_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000735 255.0
PYH2_k127_8445395_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000004183 129.0
PYH2_k127_8445395_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000002548 100.0
PYH2_k127_8462697_0 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 339.0
PYH2_k127_8462697_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000001522 182.0
PYH2_k127_8462697_2 oxidoreductase activity - - - 0.000000000000000000000000000000000356 152.0
PYH2_k127_8462697_3 Tetratricopeptide repeat - - - 0.0000000000000000000001476 112.0
PYH2_k127_8462697_4 oxidoreductase activity - - - 0.00000000124 69.0
PYH2_k127_8468237_0 Glycosyl hydrolase family 92 - - - 5.212e-253 796.0
PYH2_k127_8468237_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 503.0
PYH2_k127_8468237_2 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 399.0
PYH2_k127_8468237_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000002111 219.0
PYH2_k127_8468237_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000001606 164.0
PYH2_k127_8468237_5 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000005362 139.0
PYH2_k127_8468237_6 - - - - 0.000000004756 66.0
PYH2_k127_8480632_0 hydrolase activity, acting on glycosyl bonds - - - 1.654e-198 644.0
PYH2_k127_8480632_1 von Willebrand factor, type A K07114,K12511 - - 0.00000000000000000000000000007472 130.0
PYH2_k127_8480632_2 CAAX protease self-immunity - - - 0.0000000000000000000000000001057 124.0
PYH2_k127_8480632_3 (DL)-glycerol-3-phosphatase K17623 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006066,GO:0006071,GO:0006114,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019400,GO:0019401,GO:0019751,GO:0034637,GO:0042578,GO:0043136,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046173,GO:0071704,GO:1901576,GO:1901615,GO:1901617 3.1.3.96 0.0000000002613 61.0
PYH2_k127_8480632_4 - - - - 0.000001651 60.0
PYH2_k127_8502958_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 308.0
PYH2_k127_8502958_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000922 293.0
PYH2_k127_8502958_2 Glycosyl transferase group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000001349 209.0
PYH2_k127_8502958_3 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000007382 209.0
PYH2_k127_8502958_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000003594 176.0
PYH2_k127_8502958_5 Methyltransferase FkbM domain - - - 0.000000008777 66.0
PYH2_k127_8522717_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 623.0
PYH2_k127_8522717_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 306.0
PYH2_k127_8522717_2 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 302.0
PYH2_k127_8522717_3 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001908 280.0
PYH2_k127_8522717_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004723 250.0
PYH2_k127_8522717_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K22397 - 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000001553 221.0
PYH2_k127_8522717_6 Xylose isomerase-like TIM barrel K22233 - - 0.00000000000000000000000000000000000000000000000004204 189.0
PYH2_k127_8522717_7 single-species biofilm formation - - - 0.0000000000000000000000000165 115.0
PYH2_k127_8529150_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 361.0
PYH2_k127_8529150_1 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000000000000007492 207.0
PYH2_k127_8529150_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000001084 209.0
PYH2_k127_8529150_3 Tetratricopeptide repeat - - - 0.000000052 66.0
PYH2_k127_8536173_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.138e-261 811.0
PYH2_k127_8536173_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 4.753e-259 815.0
PYH2_k127_8536173_10 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 421.0
PYH2_k127_8536173_11 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 399.0
PYH2_k127_8536173_12 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 395.0
PYH2_k127_8536173_13 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 328.0
PYH2_k127_8536173_14 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 303.0
PYH2_k127_8536173_15 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001746 254.0
PYH2_k127_8536173_16 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
PYH2_k127_8536173_17 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000008081 261.0
PYH2_k127_8536173_18 thiolester hydrolase activity K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.00000000000000000000000000000000000000000000000000000000000000000422 246.0
PYH2_k127_8536173_19 Type II secretory pathway component ExeA K02450 - - 0.000000000000000000000000000000000000000000000000000000000001145 229.0
PYH2_k127_8536173_2 Tetratricopeptide repeat - - - 4.995e-213 689.0
PYH2_k127_8536173_20 arylamine N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000008756 216.0
PYH2_k127_8536173_21 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000001406 192.0
PYH2_k127_8536173_22 heat shock protein binding K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000005938 194.0
PYH2_k127_8536173_23 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000006523 177.0
PYH2_k127_8536173_24 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000001381 170.0
PYH2_k127_8536173_25 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000000000000000000000000000000000000000155 160.0
PYH2_k127_8536173_26 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000007821 161.0
PYH2_k127_8536173_27 Transcriptional regulator - - - 0.000000000000000000000000000004234 124.0
PYH2_k127_8536173_28 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000004208 78.0
PYH2_k127_8536173_29 TIGRFAM TonB K03832 - - 0.0000003612 60.0
PYH2_k127_8536173_3 Glucuronate isomerase K01812 - 5.3.1.12 3.881e-209 659.0
PYH2_k127_8536173_4 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 575.0
PYH2_k127_8536173_5 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 559.0
PYH2_k127_8536173_6 Iron-sulfur cluster-binding domain K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 532.0
PYH2_k127_8536173_7 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 533.0
PYH2_k127_8536173_8 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 473.0
PYH2_k127_8536173_9 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 439.0
PYH2_k127_8547933_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 6.789e-301 930.0
PYH2_k127_8547933_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 599.0
PYH2_k127_8547933_2 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 561.0
PYH2_k127_8547933_3 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 414.0
PYH2_k127_8547933_4 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 289.0
PYH2_k127_8547933_5 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 286.0
PYH2_k127_8547933_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000153 274.0
PYH2_k127_8547933_7 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 262.0
PYH2_k127_8547933_8 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000011 136.0
PYH2_k127_8547933_9 SMART Rhodanese domain protein - - - 0.0000001815 53.0
PYH2_k127_8548471_0 Fumarase C C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 568.0
PYH2_k127_8548471_1 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 434.0
PYH2_k127_8548471_2 PIN domain - - - 0.0000000000000000000000000000000000000000000002126 173.0
PYH2_k127_8548471_3 - - - - 0.00000000000000000001027 94.0
PYH2_k127_8557604_0 Carboxypeptidase regulatory-like domain - - - 5.124e-284 893.0
PYH2_k127_8557604_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 536.0
PYH2_k127_8557604_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 391.0
PYH2_k127_8557604_3 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 411.0
PYH2_k127_8557604_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000001236 210.0
PYH2_k127_8557604_5 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000478 143.0
PYH2_k127_8565277_0 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000009388 219.0
PYH2_k127_8566980_0 Involved in the tonB-independent uptake of proteins K03641 - - 7.776e-252 801.0
PYH2_k127_8566980_1 Serine hydrolase (FSH1) - - - 2.569e-247 781.0
PYH2_k127_8566980_10 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 296.0
PYH2_k127_8566980_11 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004339 276.0
PYH2_k127_8566980_12 - - - - 0.000000000000000000000000000000000000000000000000000001237 205.0
PYH2_k127_8566980_13 PHP domain protein - - - 0.000000000000000000000000000000000000000000000008248 191.0
PYH2_k127_8566980_14 SnoaL-like domain - - - 0.00000000000000000000000000000001547 131.0
PYH2_k127_8566980_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000002844 143.0
PYH2_k127_8566980_16 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000002662 123.0
PYH2_k127_8566980_2 COG3119 Arylsulfatase A K01138 - - 2.157e-203 644.0
PYH2_k127_8566980_3 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 614.0
PYH2_k127_8566980_4 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 603.0
PYH2_k127_8566980_5 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 553.0
PYH2_k127_8566980_6 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 468.0
PYH2_k127_8566980_7 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 428.0
PYH2_k127_8566980_8 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 319.0
PYH2_k127_8566980_9 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 304.0
PYH2_k127_8576429_0 PFAM General secretory system II protein E domain protein K11740 - - 5.123e-240 814.0
PYH2_k127_8576429_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 601.0
PYH2_k127_8576429_10 Methyltransferase domain K15942 - 2.1.1.288 0.000000000000000000008449 103.0
PYH2_k127_8576429_11 - - - - 0.000000000000000000009981 95.0
PYH2_k127_8576429_12 - - - - 0.000000000000000003556 88.0
PYH2_k127_8576429_13 Phage integrase family - - - 0.0000001493 54.0
PYH2_k127_8576429_16 Transposase DDE domain - - - 0.0007335 51.0
PYH2_k127_8576429_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 560.0
PYH2_k127_8576429_3 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 451.0
PYH2_k127_8576429_4 Bacteriophage N adsorption protein A C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 497.0
PYH2_k127_8576429_5 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 293.0
PYH2_k127_8576429_6 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 291.0
PYH2_k127_8576429_7 Domain of unknown function (DUF4434) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001794 286.0
PYH2_k127_8576429_8 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000001102 215.0
PYH2_k127_8576429_9 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.00000000000000000000000000000000000000000000000223 178.0
PYH2_k127_8604014_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.742e-259 816.0
PYH2_k127_8604014_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 600.0
PYH2_k127_8604014_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 582.0
PYH2_k127_8604014_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 441.0
PYH2_k127_8604014_4 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 349.0
PYH2_k127_8604014_5 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 349.0
PYH2_k127_8604014_6 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002315 232.0
PYH2_k127_8604014_7 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.0000000000001549 70.0
PYH2_k127_8604014_8 Pfam:N_methyl_2 - - - 0.0006705 49.0
PYH2_k127_8621385_1 Peptidase family M28 - - - 0.0000000000000007892 90.0
PYH2_k127_8637740_0 PFAM glycosyl hydrolase - - - 3.163e-269 849.0
PYH2_k127_8637740_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 375.0
PYH2_k127_8637740_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000001973 141.0
PYH2_k127_8637740_3 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000005325 141.0
PYH2_k127_8637740_4 - - - - 0.000000000000000000003953 94.0
PYH2_k127_8665458_0 arylsulfatase A K01130 - 3.1.6.1 6.707e-215 677.0
PYH2_k127_8665458_1 Sulfatase K01130 - 3.1.6.1 1.494e-207 662.0
PYH2_k127_8665458_2 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002618 294.0
PYH2_k127_8665458_3 (twin-arginine translocation) pathway signal - - - 0.000000008057 58.0
PYH2_k127_8717622_0 Tricorn protease homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 500.0
PYH2_k127_8717622_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 371.0
PYH2_k127_8717622_10 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000006258 61.0
PYH2_k127_8717622_11 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.0001974 55.0
PYH2_k127_8717622_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 313.0
PYH2_k127_8717622_3 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000668 253.0
PYH2_k127_8717622_4 kinase activity K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000000000000000000000000000000000000000000005613 229.0
PYH2_k127_8717622_5 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000007596 225.0
PYH2_k127_8717622_6 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000008191 132.0
PYH2_k127_8717622_7 oxidoreductase activity - - - 0.00000000000002985 87.0
PYH2_k127_8717622_8 BNR repeat-like domain - - - 0.000000009088 59.0
PYH2_k127_8717622_9 - - - - 0.0000009152 64.0
PYH2_k127_8725620_0 FAD linked oxidases, C-terminal domain - - - 9.833e-300 947.0
PYH2_k127_8725620_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 397.0
PYH2_k127_8725620_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
PYH2_k127_8725620_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000724 159.0
PYH2_k127_8725620_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000008107 143.0
PYH2_k127_8725620_6 Sporulation related domain - - - 0.000008402 58.0
PYH2_k127_8725620_7 Pilus assembly protein PilX K02673 - - 0.0005975 53.0
PYH2_k127_8733225_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0000000000000000000000000000000000000000000000000000000000000000003531 235.0
PYH2_k127_8733225_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000001821 174.0
PYH2_k127_8734229_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001897 249.0
PYH2_k127_8734229_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007802 257.0
PYH2_k127_8734229_2 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000003918 171.0
PYH2_k127_8734229_3 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000282 119.0
PYH2_k127_8734229_4 - - - - 0.00000002357 66.0
PYH2_k127_8734229_5 Histidine kinase - - - 0.0007674 51.0
PYH2_k127_8737884_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.671e-250 781.0
PYH2_k127_8737884_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005172 237.0
PYH2_k127_8737884_2 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000002093 173.0
PYH2_k127_8759538_0 PFAM Uncharacterised BCR, COG1649 - - - 2.659e-273 861.0
PYH2_k127_8759538_1 PFAM Carbohydrate kinase K00853 - 2.7.1.16 2.161e-217 687.0
PYH2_k127_8759538_2 Phosphotransferase System K02798,K02799,K02800 - 2.7.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 415.0
PYH2_k127_8759538_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 384.0
PYH2_k127_8759538_4 Integrase - - - 0.0000000000000000002394 91.0
PYH2_k127_8759538_5 Integrase - - - 0.000000000000000004556 85.0
PYH2_k127_8762632_0 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 321.0
PYH2_k127_8762632_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 305.0
PYH2_k127_8762632_2 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000003945 121.0
PYH2_k127_8762632_3 Putative cyclase - - - 0.00000000000000000000001383 102.0
PYH2_k127_8762632_4 - - - - 0.0000000000001138 78.0
PYH2_k127_8762632_5 PFAM GCN5-related N-acetyltransferase K03825 - - 0.0000007625 51.0
PYH2_k127_8794082_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 526.0
PYH2_k127_8800176_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1218.0
PYH2_k127_8800176_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 449.0
PYH2_k127_8800176_2 ATP:ADP antiporter activity K01932,K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 368.0
PYH2_k127_8800176_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 341.0
PYH2_k127_8800176_4 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 319.0
PYH2_k127_8800176_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 290.0
PYH2_k127_8800176_6 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005602 287.0
PYH2_k127_8800176_7 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006101 289.0
PYH2_k127_8805302_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.626e-213 670.0
PYH2_k127_8805302_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 593.0
PYH2_k127_8805302_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 340.0
PYH2_k127_8805302_3 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.0000000000000000000000000000000001436 136.0
PYH2_k127_8805302_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000001782 100.0
PYH2_k127_8805302_5 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000000001143 66.0
PYH2_k127_8805302_6 4Fe-4S single cluster domain - - - 0.000004553 55.0
PYH2_k127_8824614_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1278.0
PYH2_k127_8824614_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1129.0
PYH2_k127_8824614_10 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 569.0
PYH2_k127_8824614_11 carbohydrate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 527.0
PYH2_k127_8824614_12 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 518.0
PYH2_k127_8824614_13 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 496.0
PYH2_k127_8824614_14 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 496.0
PYH2_k127_8824614_15 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 458.0
PYH2_k127_8824614_16 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 441.0
PYH2_k127_8824614_17 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 468.0
PYH2_k127_8824614_18 belongs to the nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 386.0
PYH2_k127_8824614_19 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 402.0
PYH2_k127_8824614_2 Belongs to the carbamoyltransferase HypF family K04656 - - 1.335e-271 859.0
PYH2_k127_8824614_20 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 363.0
PYH2_k127_8824614_21 Belongs to the NadC ModD family K00767,K03813 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 321.0
PYH2_k127_8824614_22 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 309.0
PYH2_k127_8824614_23 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 311.0
PYH2_k127_8824614_24 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 292.0
PYH2_k127_8824614_25 Participates in the control of copper homeostasis K06201 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005923 284.0
PYH2_k127_8824614_26 Alkyl hydroperoxide reductase and or thiol-specific antioxidant family (AhpC TSA) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001097 280.0
PYH2_k127_8824614_27 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002095 269.0
PYH2_k127_8824614_28 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005911 278.0
PYH2_k127_8824614_29 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
PYH2_k127_8824614_3 Penicillin amidase K01434 - 3.5.1.11 1.969e-229 732.0
PYH2_k127_8824614_30 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003521 252.0
PYH2_k127_8824614_31 RNA-DNA hybrid ribonuclease activity K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000008004 231.0
PYH2_k127_8824614_32 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000005662 212.0
PYH2_k127_8824614_33 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000002766 180.0
PYH2_k127_8824614_34 - - - - 0.00000000000000000000000000000000000000000000005562 176.0
PYH2_k127_8824614_36 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000001188 154.0
PYH2_k127_8824614_37 NUDIX domain - - - 0.000000000000000000000000000000000000002211 154.0
PYH2_k127_8824614_38 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000001426 153.0
PYH2_k127_8824614_39 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000000001072 123.0
PYH2_k127_8824614_4 serine-type peptidase activity K01278 - 3.4.14.5 2.019e-227 727.0
PYH2_k127_8824614_40 Belongs to the Fur family K09825 - - 0.000000000000000000000000003072 117.0
PYH2_k127_8824614_41 Smr domain - - - 0.00000000000000000000002622 102.0
PYH2_k127_8824614_42 von Willebrand factor, type A - - - 0.0000000000000000000005489 108.0
PYH2_k127_8824614_43 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000003011 99.0
PYH2_k127_8824614_44 Tetratricopeptide repeat - - - 0.0000000000000002623 93.0
PYH2_k127_8824614_45 I and II - - - 0.00003744 48.0
PYH2_k127_8824614_46 electron transfer activity - - - 0.0001491 49.0
PYH2_k127_8824614_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.998e-204 662.0
PYH2_k127_8824614_6 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 5.166e-202 636.0
PYH2_k127_8824614_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.397e-201 638.0
PYH2_k127_8824614_8 Cysteine-rich domain K00113 - 1.1.5.3 4.278e-198 625.0
PYH2_k127_8824614_9 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 574.0
PYH2_k127_8827097_0 PFAM RNA polymerase sigma factor 54, interaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 557.0
PYH2_k127_8829753_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003726 260.0
PYH2_k127_8829753_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000314 235.0
PYH2_k127_8878249_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1033.0
PYH2_k127_8878249_1 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 2.091e-271 860.0
PYH2_k127_8878249_10 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001247 261.0
PYH2_k127_8878249_11 Domain of unknown function K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000003088 235.0
PYH2_k127_8878249_12 pfam nipsnap - - - 0.000000000000000000000000000000000000000000000000584 186.0
PYH2_k127_8878249_13 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.000000000000000000000000000000000000000000000769 172.0
PYH2_k127_8878249_14 Domains LysM, LysM, NLPC_P60 K19223 - - 0.000000000000000000000000000000000003216 149.0
PYH2_k127_8878249_15 Beta-lactamase - - - 0.000000000000000000000000000000000005917 147.0
PYH2_k127_8878249_16 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000003339 128.0
PYH2_k127_8878249_17 PFAM Beta-lactamase - - - 0.0000000000000000000003099 102.0
PYH2_k127_8878249_18 GGDEF domain K03407,K07648,K07679,K11356 - 2.7.13.3 0.00000000000000921 87.0
PYH2_k127_8878249_19 peptidyl-tyrosine sulfation - - - 0.0000000000001466 84.0
PYH2_k127_8878249_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 578.0
PYH2_k127_8878249_20 Histidine kinase K13587 - 2.7.13.3 0.00000118 64.0
PYH2_k127_8878249_21 3D domain - - - 0.00000173 57.0
PYH2_k127_8878249_3 gluconolactonase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 506.0
PYH2_k127_8878249_4 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 457.0
PYH2_k127_8878249_5 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 426.0
PYH2_k127_8878249_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 408.0
PYH2_k127_8878249_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 391.0
PYH2_k127_8878249_8 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
PYH2_k127_8878249_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 338.0
PYH2_k127_8966616_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 402.0
PYH2_k127_8966616_1 sugar kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 377.0
PYH2_k127_8966616_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 336.0
PYH2_k127_8966616_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 312.0
PYH2_k127_8966616_4 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 279.0
PYH2_k127_8966616_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000005074 148.0
PYH2_k127_9026993_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 406.0
PYH2_k127_9026993_1 MFS_1 like family K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 353.0
PYH2_k127_9026993_2 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000006849 227.0
PYH2_k127_9026993_3 reverse transcriptase - - - 0.00000000000000000000000002762 114.0
PYH2_k127_9069488_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 5.884e-262 822.0
PYH2_k127_9069488_1 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 595.0
PYH2_k127_9069488_10 Methyltransferase small domain - - - 0.000009334 55.0
PYH2_k127_9069488_2 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 531.0
PYH2_k127_9069488_3 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 490.0
PYH2_k127_9069488_4 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 291.0
PYH2_k127_9069488_5 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 310.0
PYH2_k127_9069488_6 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001478 262.0
PYH2_k127_9069488_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000004282 217.0
PYH2_k127_9069488_8 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000001837 197.0
PYH2_k127_9069488_9 addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000000000000000000000003017 151.0
PYH2_k127_9082412_0 PFAM Phenylalanine and histidine ammonia-lyase K01745,K10775 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.24,4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 526.0
PYH2_k127_9082412_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 439.0
PYH2_k127_9082412_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 397.0
PYH2_k127_9082412_3 PFAM Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 397.0
PYH2_k127_9082412_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 350.0
PYH2_k127_9082412_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 343.0
PYH2_k127_9082412_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
PYH2_k127_9082412_7 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000001205 117.0
PYH2_k127_9082412_8 COG0457 FOG TPR repeat - - - 0.00000001083 66.0
PYH2_k127_9084621_0 TIGRFAM urea ABC transporter, ATP-binding protein UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006314 283.0
PYH2_k127_9084621_1 TIGRFAM urea ABC transporter, ATP-binding protein UrtE K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002403 255.0
PYH2_k127_9087904_0 PFAM Carbohydrate kinase K00853 - 2.7.1.16 7.273e-251 784.0
PYH2_k127_9087904_1 Belongs to the glycosyl hydrolase 2 family - - - 2.574e-194 625.0
PYH2_k127_9087904_10 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 368.0
PYH2_k127_9087904_11 PFAM Class II aldolase K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 313.0
PYH2_k127_9087904_12 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 312.0
PYH2_k127_9087904_13 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 318.0
PYH2_k127_9087904_14 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 287.0
PYH2_k127_9087904_15 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000495 268.0
PYH2_k127_9087904_16 Glucose dehydrogenase C-terminus K00008,K05351 - 1.1.1.14,1.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000008957 255.0
PYH2_k127_9087904_17 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002693 236.0
PYH2_k127_9087904_18 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000003288 227.0
PYH2_k127_9087904_19 - - - - 0.00000000000000000000000000000000000000000000000000000007235 202.0
PYH2_k127_9087904_2 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 612.0
PYH2_k127_9087904_20 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000004508 205.0
PYH2_k127_9087904_21 TonB dependent receptor K16087 - - 0.00000000000000000000000000000000000000006788 175.0
PYH2_k127_9087904_22 Alpha/beta hydrolase family - - - 0.00000000000000000000000000007003 130.0
PYH2_k127_9087904_23 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000000005713 120.0
PYH2_k127_9087904_25 GMP synthase-glutamine amidotransferase - - - 0.0001619 53.0
PYH2_k127_9087904_3 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 584.0
PYH2_k127_9087904_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 569.0
PYH2_k127_9087904_5 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 556.0
PYH2_k127_9087904_6 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 515.0
PYH2_k127_9087904_7 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 490.0
PYH2_k127_9087904_8 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 477.0
PYH2_k127_9087904_9 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 447.0
PYH2_k127_9136561_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 399.0
PYH2_k127_9136561_1 TIGRFAM amino acid adenylation domain - - - 0.000001489 54.0
PYH2_k127_9139123_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 453.0
PYH2_k127_9139123_1 Domain of unknown function (DUF4962) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 336.0
PYH2_k127_9161951_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1112.0
PYH2_k127_9161951_1 Glycosyl hydrolases family 2, TIM barrel domain K01190,K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 0.0 1105.0
PYH2_k127_9161951_10 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000307 269.0
PYH2_k127_9161951_11 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004178 273.0
PYH2_k127_9161951_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000001512 246.0
PYH2_k127_9161951_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000001282 220.0
PYH2_k127_9161951_14 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000008247 222.0
PYH2_k127_9161951_15 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000000000000000000000921 193.0
PYH2_k127_9161951_16 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000005714 180.0
PYH2_k127_9161951_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000000002159 146.0
PYH2_k127_9161951_18 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000001799 152.0
PYH2_k127_9161951_19 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000009724 137.0
PYH2_k127_9161951_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 572.0
PYH2_k127_9161951_20 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000001904 124.0
PYH2_k127_9161951_21 Transcriptional regulator ArsR family - - - 0.00000000000000000000000001963 112.0
PYH2_k127_9161951_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000001119 115.0
PYH2_k127_9161951_23 DNA-templated transcription, initiation K03088 - - 0.00000000000002326 87.0
PYH2_k127_9161951_25 protein N-acetylglucosaminyltransferase activity K01025 - - 0.00000000007587 75.0
PYH2_k127_9161951_3 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 541.0
PYH2_k127_9161951_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 414.0
PYH2_k127_9161951_5 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 338.0
PYH2_k127_9161951_6 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 331.0
PYH2_k127_9161951_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 318.0
PYH2_k127_9161951_8 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 303.0
PYH2_k127_9161951_9 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 295.0
PYH2_k127_9168166_0 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 449.0
PYH2_k127_9168166_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 420.0
PYH2_k127_9168166_10 energy transducer activity K03646,K03832 - - 0.00001959 55.0
PYH2_k127_9168166_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 399.0
PYH2_k127_9168166_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 390.0
PYH2_k127_9168166_4 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 314.0
PYH2_k127_9168166_5 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000002194 246.0
PYH2_k127_9168166_6 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000001771 198.0
PYH2_k127_9168166_7 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000007815 178.0
PYH2_k127_9168166_8 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000003805 124.0
PYH2_k127_9168166_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000008619 110.0
PYH2_k127_941793_0 Elongator protein 3, MiaB family, Radical SAM - - - 9.527e-203 642.0
PYH2_k127_941793_1 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 548.0
PYH2_k127_941793_11 Phage integrase family - - - 0.00002748 55.0
PYH2_k127_941793_12 TrwC relaxase - - - 0.00005155 48.0
PYH2_k127_941793_2 transmembrane transporter activity K03535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007414 270.0
PYH2_k127_941793_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000003096 243.0
PYH2_k127_941793_4 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000002433 179.0
PYH2_k127_941793_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000003535 163.0
PYH2_k127_941793_6 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000001475 145.0
PYH2_k127_941793_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000006154 129.0
PYH2_k127_941793_8 dienelactone hydrolase - - - 0.00000000000000000000000000000002304 131.0
PYH2_k127_941793_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002072 126.0
PYH2_k127_943414_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 254.0
PYH2_k127_943414_1 PFAM plasmid stabilization system - - - 0.000000000000000000000000000000000000001334 149.0
PYH2_k127_943414_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000000006088 142.0
PYH2_k127_943414_3 Ectoine synthase - - - 0.000000000000000000000000000000000006878 142.0
PYH2_k127_943414_4 Plasmid stabilization system - - - 0.000000000000000000000000000001095 124.0
PYH2_k127_943414_5 Protein of unknown function DUF86 - - - 0.000000000000000003174 85.0
PYH2_k127_943414_6 PilZ domain - - - 0.000000000001145 74.0
PYH2_k127_943414_7 PIN domain - - - 0.0000002623 60.0
PYH2_k127_943414_8 Putative addiction module component - - - 0.0000008475 53.0
PYH2_k127_943618_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000044 259.0
PYH2_k127_943618_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000002195 139.0
PYH2_k127_944750_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 1.377e-300 940.0
PYH2_k127_944750_1 mannose metabolic process K01191 - 3.2.1.24 1.234e-296 940.0
PYH2_k127_944750_10 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 496.0
PYH2_k127_944750_100 Beta-lactamase - - - 0.000007515 57.0
PYH2_k127_944750_101 Transcriptional regulator, MarR family - - - 0.00002289 54.0
PYH2_k127_944750_102 Bacterial antitoxin of type II TA system, VapB - - - 0.00004522 49.0
PYH2_k127_944750_103 Chaperone protein DNAJ-like protein - - - 0.00005869 48.0
PYH2_k127_944750_104 Tfp pilus assembly protein FimV - - - 0.00009106 46.0
PYH2_k127_944750_11 glucose-1-phosphate adenylyltransferase K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 476.0
PYH2_k127_944750_12 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 487.0
PYH2_k127_944750_13 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 480.0
PYH2_k127_944750_14 response regulator K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 458.0
PYH2_k127_944750_15 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 462.0
PYH2_k127_944750_16 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 444.0
PYH2_k127_944750_17 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 430.0
PYH2_k127_944750_18 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 430.0
PYH2_k127_944750_19 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 418.0
PYH2_k127_944750_2 FAD dependent oxidoreductase - - - 1.649e-270 846.0
PYH2_k127_944750_20 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 412.0
PYH2_k127_944750_21 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
PYH2_k127_944750_22 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 411.0
PYH2_k127_944750_23 DNA photolyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 401.0
PYH2_k127_944750_24 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 400.0
PYH2_k127_944750_25 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 395.0
PYH2_k127_944750_26 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 393.0
PYH2_k127_944750_27 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 376.0
PYH2_k127_944750_28 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 362.0
PYH2_k127_944750_29 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 360.0
PYH2_k127_944750_3 Belongs to the peptidase S16 family K04076 - 3.4.21.53 9.044e-248 790.0
PYH2_k127_944750_30 Cytochrome bd terminal oxidase subunit I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 366.0
PYH2_k127_944750_31 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 354.0
PYH2_k127_944750_32 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 348.0
PYH2_k127_944750_33 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 344.0
PYH2_k127_944750_34 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 349.0
PYH2_k127_944750_35 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 344.0
PYH2_k127_944750_36 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 337.0
PYH2_k127_944750_37 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 329.0
PYH2_k127_944750_38 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 335.0
PYH2_k127_944750_39 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 334.0
PYH2_k127_944750_4 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.468e-233 737.0
PYH2_k127_944750_40 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 319.0
PYH2_k127_944750_41 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 321.0
PYH2_k127_944750_42 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 316.0
PYH2_k127_944750_43 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 321.0
PYH2_k127_944750_44 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 306.0
PYH2_k127_944750_45 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 302.0
PYH2_k127_944750_46 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 305.0
PYH2_k127_944750_47 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 304.0
PYH2_k127_944750_48 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 301.0
PYH2_k127_944750_49 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 298.0
PYH2_k127_944750_5 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 607.0
PYH2_k127_944750_50 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 287.0
PYH2_k127_944750_51 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008243 282.0
PYH2_k127_944750_52 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
PYH2_k127_944750_53 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
PYH2_k127_944750_54 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
PYH2_k127_944750_55 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 275.0
PYH2_k127_944750_56 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000001018 253.0
PYH2_k127_944750_57 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001494 243.0
PYH2_k127_944750_58 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000001455 244.0
PYH2_k127_944750_59 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000001011 231.0
PYH2_k127_944750_6 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 568.0
PYH2_k127_944750_60 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000181 240.0
PYH2_k127_944750_61 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000004665 232.0
PYH2_k127_944750_62 cobalamin binding K01647,K18997,K22491 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000006506 231.0
PYH2_k127_944750_63 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000001422 224.0
PYH2_k127_944750_64 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
PYH2_k127_944750_65 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001879 221.0
PYH2_k127_944750_66 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000003191 215.0
PYH2_k127_944750_67 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000001273 216.0
PYH2_k127_944750_68 pfam nudix - - - 0.00000000000000000000000000000000000000000000000000000003266 203.0
PYH2_k127_944750_69 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000004061 209.0
PYH2_k127_944750_7 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 553.0
PYH2_k127_944750_70 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000004451 213.0
PYH2_k127_944750_71 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000004136 192.0
PYH2_k127_944750_72 iron ion homeostasis K03709,K04758 - - 0.00000000000000000000000000000000000000000000000001896 191.0
PYH2_k127_944750_73 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000005375 188.0
PYH2_k127_944750_74 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000006204 197.0
PYH2_k127_944750_75 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000003718 184.0
PYH2_k127_944750_76 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000001226 171.0
PYH2_k127_944750_77 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000008012 169.0
PYH2_k127_944750_78 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000003123 160.0
PYH2_k127_944750_79 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000000008049 156.0
PYH2_k127_944750_8 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 503.0
PYH2_k127_944750_80 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000003736 154.0
PYH2_k127_944750_81 ACT domain K03567 - - 0.000000000000000000000000000000000000007806 152.0
PYH2_k127_944750_82 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000008534 150.0
PYH2_k127_944750_83 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000001809 163.0
PYH2_k127_944750_84 chlorophyll binding - - - 0.000000000000000000000000000002368 134.0
PYH2_k127_944750_85 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000000000004529 128.0
PYH2_k127_944750_86 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000001071 130.0
PYH2_k127_944750_87 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000001465 118.0
PYH2_k127_944750_88 Putative regulatory protein - - - 0.00000000000000000000000000001791 124.0
PYH2_k127_944750_89 spore germination K03605 - - 0.0000000000000000000000000001572 123.0
PYH2_k127_944750_9 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 493.0
PYH2_k127_944750_90 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000003061 114.0
PYH2_k127_944750_91 oxidase subunit K08738 - - 0.0000000000000000000000002477 119.0
PYH2_k127_944750_92 Tetratricopeptide repeat - - - 0.0000000000000000000000008555 115.0
PYH2_k127_944750_93 DRTGG domain - - - 0.000000000000000000000005519 109.0
PYH2_k127_944750_94 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000014 113.0
PYH2_k127_944750_96 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000004162 99.0
PYH2_k127_944750_97 - - - - 0.0000000000000001569 93.0
PYH2_k127_944750_98 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.00000002141 57.0
PYH2_k127_944750_99 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000002132 59.0
PYH2_k127_945356_0 COG COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 468.0
PYH2_k127_945356_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000003767 59.0
PYH2_k127_950161_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 591.0
PYH2_k127_950161_1 PFAM Response regulator receiver domain K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 495.0
PYH2_k127_950161_2 V4R - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000105 272.0
PYH2_k127_950161_3 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
PYH2_k127_950161_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001978 206.0
PYH2_k127_950161_5 GtrA-like protein - - - 0.00000000000000000000000000002871 130.0
PYH2_k127_959665_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 378.0
PYH2_k127_959665_1 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002438 275.0
PYH2_k127_959665_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001375 279.0
PYH2_k127_961277_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1153.0
PYH2_k127_961277_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.357e-314 986.0
PYH2_k127_961277_10 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 404.0
PYH2_k127_961277_11 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 372.0
PYH2_k127_961277_12 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 388.0
PYH2_k127_961277_13 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 364.0
PYH2_k127_961277_14 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
PYH2_k127_961277_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 338.0
PYH2_k127_961277_16 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 322.0
PYH2_k127_961277_17 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 317.0
PYH2_k127_961277_18 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 306.0
PYH2_k127_961277_19 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 267.0
PYH2_k127_961277_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 9.559e-276 875.0
PYH2_k127_961277_20 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001994 243.0
PYH2_k127_961277_21 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000008263 249.0
PYH2_k127_961277_22 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000004443 240.0
PYH2_k127_961277_23 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000005264 226.0
PYH2_k127_961277_24 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000000000000000000000008646 208.0
PYH2_k127_961277_25 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000000000002934 187.0
PYH2_k127_961277_26 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000001629 174.0
PYH2_k127_961277_27 PFAM RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000000000000000000000000000000000001534 173.0
PYH2_k127_961277_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001578 172.0
PYH2_k127_961277_29 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000001999 173.0
PYH2_k127_961277_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.318e-254 810.0
PYH2_k127_961277_30 LacY proton/sugar symporter - - - 0.00000000000000000000000000000000000000002048 168.0
PYH2_k127_961277_31 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000006029 160.0
PYH2_k127_961277_32 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000009028 164.0
PYH2_k127_961277_33 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.000000000000000000000000000000000000005568 149.0
PYH2_k127_961277_34 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000001189 155.0
PYH2_k127_961277_35 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000001372 148.0
PYH2_k127_961277_36 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000746 141.0
PYH2_k127_961277_37 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000002984 148.0
PYH2_k127_961277_38 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000001169 148.0
PYH2_k127_961277_39 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000001281 145.0
PYH2_k127_961277_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.299e-196 623.0
PYH2_k127_961277_40 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000002357 149.0
PYH2_k127_961277_41 Cupin domain - - - 0.000000000000000000000000000000006413 139.0
PYH2_k127_961277_42 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000002451 124.0
PYH2_k127_961277_43 Involved in chromosome partitioning - - - 0.00000000000000000000000000007291 125.0
PYH2_k127_961277_44 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000206 127.0
PYH2_k127_961277_45 cheY-homologous receiver domain - - - 0.0000000000000000000000000933 115.0
PYH2_k127_961277_46 Glycoprotease family - - - 0.0000000000000000000000002584 116.0
PYH2_k127_961277_47 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000007997 116.0
PYH2_k127_961277_48 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000001307 90.0
PYH2_k127_961277_49 - - - - 0.00000000000000003682 86.0
PYH2_k127_961277_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 521.0
PYH2_k127_961277_50 FR47-like protein K03789 - 2.3.1.128 0.0000000000001148 78.0
PYH2_k127_961277_51 - - - - 0.0000000002907 72.0
PYH2_k127_961277_52 - - - - 0.0000000003733 72.0
PYH2_k127_961277_53 - - - - 0.00000001374 62.0
PYH2_k127_961277_54 - - - - 0.0000004447 59.0
PYH2_k127_961277_56 Carboxymuconolactone decarboxylase family - - - 0.000002155 59.0
PYH2_k127_961277_57 Regulatory protein recX K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00003639 55.0
PYH2_k127_961277_6 PFAM MgsA AAA ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 478.0
PYH2_k127_961277_7 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 470.0
PYH2_k127_961277_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 412.0
PYH2_k127_961277_9 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 407.0
PYH2_k127_963742_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.397e-288 897.0
PYH2_k127_963742_1 Belongs to the UbiD family K03182 - 4.1.1.98 4.676e-206 657.0
PYH2_k127_963742_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 615.0
PYH2_k127_963742_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 518.0
PYH2_k127_963742_4 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 503.0
PYH2_k127_963742_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 334.0
PYH2_k127_963742_6 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002529 243.0
PYH2_k127_963742_7 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
PYH2_k127_963742_8 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000003965 160.0
PYH2_k127_963742_9 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000006979 151.0
PYH2_k127_964338_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 4.483e-254 798.0
PYH2_k127_964338_1 HELICc2 K03722 - 3.6.4.12 1.542e-208 668.0
PYH2_k127_964338_10 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 382.0
PYH2_k127_964338_11 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 379.0
PYH2_k127_964338_12 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 340.0
PYH2_k127_964338_13 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 323.0
PYH2_k127_964338_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 323.0
PYH2_k127_964338_15 Uncharacterised conserved protein (DUF2156) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 333.0
PYH2_k127_964338_16 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000006142 252.0
PYH2_k127_964338_17 protein histidine kinase activity K02484,K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000011 240.0
PYH2_k127_964338_18 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000002704 233.0
PYH2_k127_964338_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 632.0
PYH2_k127_964338_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000009146 228.0
PYH2_k127_964338_21 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000001919 227.0
PYH2_k127_964338_22 - - - - 0.000000000000000000000000000000000000000000000000000000000006874 217.0
PYH2_k127_964338_23 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000005321 201.0
PYH2_k127_964338_24 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000001604 195.0
PYH2_k127_964338_25 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000001895 177.0
PYH2_k127_964338_26 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000001354 177.0
PYH2_k127_964338_27 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000006277 168.0
PYH2_k127_964338_29 PFAM Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000004413 163.0
PYH2_k127_964338_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 621.0
PYH2_k127_964338_30 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000001435 156.0
PYH2_k127_964338_31 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000007082 152.0
PYH2_k127_964338_32 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000001041 152.0
PYH2_k127_964338_33 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000001973 144.0
PYH2_k127_964338_34 ECF sigma factor K03088 - - 0.000000000000000000000000000000004326 137.0
PYH2_k127_964338_35 Ubiquinol-cytochrome C reductase - - - 0.000000000000000000000000000000008455 133.0
PYH2_k127_964338_36 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000009269 115.0
PYH2_k127_964338_37 Belongs to the peptidase S1C family - - - 0.000000000000000000000001792 118.0
PYH2_k127_964338_38 Tetratricopeptide repeat - - - 0.0000000000000000000001124 105.0
PYH2_k127_964338_39 Glycosyltransferase like family 2 K20444 - - 0.0000000000000000000007926 105.0
PYH2_k127_964338_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 593.0
PYH2_k127_964338_40 SNARE associated Golgi protein - GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000001928 110.0
PYH2_k127_964338_41 - - - - 0.000000000000000000002228 98.0
PYH2_k127_964338_42 - - - - 0.000000000000000002989 89.0
PYH2_k127_964338_43 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000972 81.0
PYH2_k127_964338_44 PFAM glycine cleavage H-protein - - - 0.000000000000004234 85.0
PYH2_k127_964338_45 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000002197 78.0
PYH2_k127_964338_46 DinB superfamily - - - 0.0000000002362 70.0
PYH2_k127_964338_47 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000008957 65.0
PYH2_k127_964338_48 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000009723 67.0
PYH2_k127_964338_49 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.00002038 50.0
PYH2_k127_964338_5 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 572.0
PYH2_k127_964338_50 Putative zinc-finger - - - 0.00006682 54.0
PYH2_k127_964338_6 Enolase C-terminal domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 570.0
PYH2_k127_964338_7 Sodium:sulfate symporter transmembrane region K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 447.0
PYH2_k127_964338_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 427.0
PYH2_k127_964338_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 401.0
PYH2_k127_975096_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000002231 178.0
PYH2_k127_975096_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000005925 70.0
PYH2_k127_975096_2 Redoxin - - - 0.0008481 45.0
PYH2_k127_989580_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.757e-277 873.0
PYH2_k127_989580_1 Magnesium transport protein CorA K03284 - - 4.71e-201 644.0
PYH2_k127_989580_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 370.0
PYH2_k127_989580_11 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 346.0
PYH2_k127_989580_12 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 332.0
PYH2_k127_989580_13 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 321.0
PYH2_k127_989580_14 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
PYH2_k127_989580_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001686 269.0
PYH2_k127_989580_16 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002055 248.0
PYH2_k127_989580_17 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004004 237.0
PYH2_k127_989580_18 Alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000007966 231.0
PYH2_k127_989580_19 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000002378 146.0
PYH2_k127_989580_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 574.0
PYH2_k127_989580_20 Cytochrome c K00413 - - 0.00000000000000000000000000006794 123.0
PYH2_k127_989580_21 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000002482 126.0
PYH2_k127_989580_22 Alpha/beta hydrolase family - - - 0.0000000000000000000000000004628 124.0
PYH2_k127_989580_23 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000002603 115.0
PYH2_k127_989580_24 glutamate synthase - - - 0.0000000000000000000000003072 115.0
PYH2_k127_989580_25 - - - - 0.000000000000000000000004073 108.0
PYH2_k127_989580_26 metal cluster binding - - - 0.00000000000000000000000973 108.0
PYH2_k127_989580_27 - - - - 0.00000000000000000003109 94.0
PYH2_k127_989580_28 - - - - 0.00000000000000000004642 93.0
PYH2_k127_989580_29 Domain of unknown function (DUF4388) - - - 0.0002739 54.0
PYH2_k127_989580_3 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 539.0
PYH2_k127_989580_4 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 509.0
PYH2_k127_989580_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 452.0
PYH2_k127_989580_6 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 436.0
PYH2_k127_989580_7 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 444.0
PYH2_k127_989580_8 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 424.0
PYH2_k127_989580_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 414.0