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Overview

ID MAG03177
Name PYH2_bin.17
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Fen-1058
Family Fen-1058
Genus JBGQGR01
Species
Assembly information
Completeness (%) 90.99
Contamination (%) 2.06
GC content (%) 54.0
N50 (bp) 7,330
Genome size (bp) 3,231,442

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2882

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1002921_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 411.0
PYH2_k127_1002921_1 Methyltransferase domain K06987 - - 0.0000000000000000000003014 99.0
PYH2_k127_1002921_2 - - - - 0.00001247 53.0
PYH2_k127_1002921_3 - - - - 0.00002284 55.0
PYH2_k127_1003864_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 644.0
PYH2_k127_1003864_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000004938 205.0
PYH2_k127_1011120_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 431.0
PYH2_k127_1011120_1 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000112 217.0
PYH2_k127_1011120_2 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000663 194.0
PYH2_k127_1011120_3 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000004093 63.0
PYH2_k127_1011120_4 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.0006156 49.0
PYH2_k127_1017413_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 516.0
PYH2_k127_1017413_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 429.0
PYH2_k127_1017413_2 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 380.0
PYH2_k127_1023578_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006369 284.0
PYH2_k127_1023578_1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008122 269.0
PYH2_k127_1023578_2 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003891 251.0
PYH2_k127_1023578_3 ABC transporter transmembrane region K06147 - - 0.0000000003932 62.0
PYH2_k127_102386_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
PYH2_k127_102386_1 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000003601 233.0
PYH2_k127_1025724_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.599e-258 803.0
PYH2_k127_1025724_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 1.134e-215 678.0
PYH2_k127_1025724_2 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 587.0
PYH2_k127_1025724_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 448.0
PYH2_k127_1025724_4 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000001046 130.0
PYH2_k127_1025724_5 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.0000000000000000000000000006184 119.0
PYH2_k127_1033106_0 Penicillin amidase K01434 - 3.5.1.11 9.749e-197 644.0
PYH2_k127_1033106_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.465e-194 617.0
PYH2_k127_1033106_10 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001279 265.0
PYH2_k127_1033106_11 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000008791 264.0
PYH2_k127_1033106_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001059 268.0
PYH2_k127_1033106_13 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 246.0
PYH2_k127_1033106_14 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001349 244.0
PYH2_k127_1033106_15 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
PYH2_k127_1033106_16 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000002 170.0
PYH2_k127_1033106_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000958 164.0
PYH2_k127_1033106_18 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000003245 146.0
PYH2_k127_1033106_19 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000009123 145.0
PYH2_k127_1033106_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 661.0
PYH2_k127_1033106_20 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000000001793 131.0
PYH2_k127_1033106_21 PFAM molybdopterin binding domain - - - 0.000000000000000000000003867 110.0
PYH2_k127_1033106_22 Peptidoglycan-binding lysin domain - - - 0.000000000002424 74.0
PYH2_k127_1033106_23 Belongs to the peptidase S8 family K01361,K08652,K14647 - 3.4.21.110,3.4.21.96 0.0000001485 63.0
PYH2_k127_1033106_24 Lysin motif K22409 - 3.5.1.28 0.000002589 60.0
PYH2_k127_1033106_25 Uncharacterised protein family UPF0560 - - - 0.00009548 55.0
PYH2_k127_1033106_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 542.0
PYH2_k127_1033106_4 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 484.0
PYH2_k127_1033106_5 Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 389.0
PYH2_k127_1033106_6 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 381.0
PYH2_k127_1033106_7 Leucine Rich Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
PYH2_k127_1033106_8 1-aminocyclopropane-1-carboxylate deaminase K01505,K05396 - 3.5.99.7,4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 328.0
PYH2_k127_1033106_9 TIGRFAM small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 288.0
PYH2_k127_1033232_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 495.0
PYH2_k127_1033232_1 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 362.0
PYH2_k127_1033232_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000006128 96.0
PYH2_k127_1033232_2 ABC-3 protein K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 295.0
PYH2_k127_1033232_3 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005284 271.0
PYH2_k127_1033232_4 Zinc-uptake complex component A periplasmic K02077,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003296 265.0
PYH2_k127_1033232_5 PFAM ABC transporter related K09820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005867 245.0
PYH2_k127_1033232_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000001031 223.0
PYH2_k127_1033232_7 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000002266 156.0
PYH2_k127_1033232_8 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001822 119.0
PYH2_k127_1033232_9 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001151 115.0
PYH2_k127_1039617_0 Alpha amylase, catalytic domain - - - 0.0 1335.0
PYH2_k127_1039617_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 482.0
PYH2_k127_1039617_10 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000005114 192.0
PYH2_k127_1039617_11 Transcriptional regulator - - - 0.00000000000000000000009262 107.0
PYH2_k127_1039617_12 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000002531 93.0
PYH2_k127_1039617_13 Pfam:DUF59 - - - 0.0000000000000002466 84.0
PYH2_k127_1039617_14 PFAM PBS lyase HEAT domain protein repeat-containing protein K02288 - 4.4.1.32 0.00007826 56.0
PYH2_k127_1039617_2 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 430.0
PYH2_k127_1039617_3 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 394.0
PYH2_k127_1039617_5 heat shock protein 70 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 345.0
PYH2_k127_1039617_6 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
PYH2_k127_1039617_7 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
PYH2_k127_1039617_8 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000001123 231.0
PYH2_k127_1039617_9 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000009116 228.0
PYH2_k127_1042999_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 323.0
PYH2_k127_1042999_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 294.0
PYH2_k127_1042999_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007817 274.0
PYH2_k127_1042999_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000007051 158.0
PYH2_k127_1044317_0 Belongs to the transketolase family K00615 - 2.2.1.1 1.214e-295 920.0
PYH2_k127_1044317_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 530.0
PYH2_k127_1044317_2 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000006296 79.0
PYH2_k127_1044317_3 peptidyl-tyrosine sulfation - - - 0.00002591 50.0
PYH2_k127_1044703_0 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 309.0
PYH2_k127_1044703_1 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000002809 104.0
PYH2_k127_1056080_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000001411 217.0
PYH2_k127_1056080_1 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000000000000000000000000000194 212.0
PYH2_k127_1056080_2 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000004003 188.0
PYH2_k127_1056080_3 Membrane - - - 0.0000000000000000000000000000000000005133 158.0
PYH2_k127_1057840_0 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000002546 225.0
PYH2_k127_1057840_1 exo-alpha-(2->6)-sialidase activity - - - 0.00005523 56.0
PYH2_k127_1062859_0 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 424.0
PYH2_k127_1062859_1 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001002 292.0
PYH2_k127_1062859_2 Flavin reductase like domain K00484,K16048 - 1.5.1.36 0.0000000000000000000000000000001607 129.0
PYH2_k127_1062859_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000003175 126.0
PYH2_k127_1062859_5 Pentapeptide repeats (9 copies) - - - 0.00003616 50.0
PYH2_k127_1068136_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000005969 216.0
PYH2_k127_1068136_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001711 200.0
PYH2_k127_1068136_2 SPFH domain-Band 7 family - - - 0.000000000001375 79.0
PYH2_k127_1069430_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
PYH2_k127_1069430_1 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 358.0
PYH2_k127_1069430_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 327.0
PYH2_k127_1069430_3 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
PYH2_k127_1069430_4 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 258.0
PYH2_k127_1069430_5 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007582 239.0
PYH2_k127_107158_0 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 329.0
PYH2_k127_107158_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002042 272.0
PYH2_k127_107158_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
PYH2_k127_107158_3 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
PYH2_k127_107158_4 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000001814 211.0
PYH2_k127_1081534_0 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 570.0
PYH2_k127_1081534_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000002268 254.0
PYH2_k127_1081534_2 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000008876 179.0
PYH2_k127_1081534_3 cheY-homologous receiver domain - - - 0.0000000000000003113 83.0
PYH2_k127_1113593_0 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 355.0
PYH2_k127_1113593_1 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 325.0
PYH2_k127_1113593_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007182 276.0
PYH2_k127_1113593_3 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000001808 216.0
PYH2_k127_111383_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1310.0
PYH2_k127_111383_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.207e-216 680.0
PYH2_k127_111383_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 467.0
PYH2_k127_111383_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000007049 267.0
PYH2_k127_111383_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
PYH2_k127_111383_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000001258 220.0
PYH2_k127_111383_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002842 126.0
PYH2_k127_111383_7 Acetyltransferase (GNAT) domain - - - 0.0000000000001328 77.0
PYH2_k127_111383_8 Regulator K02483 - - 0.000000001658 67.0
PYH2_k127_111383_9 - - - - 0.00006518 54.0
PYH2_k127_1117264_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 5.657e-209 677.0
PYH2_k127_1117264_1 PFAM single-stranded nucleic acid binding R3H domain protein - - - 1.179e-203 648.0
PYH2_k127_1117264_10 Putative regulatory protein - - - 0.00000000000000000000000000000005534 130.0
PYH2_k127_1117264_11 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000002822 134.0
PYH2_k127_1117264_12 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000001305 130.0
PYH2_k127_1117264_13 - - - - 0.0000000000000000000000000001649 121.0
PYH2_k127_1117264_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000002524 112.0
PYH2_k127_1117264_15 - - - - 0.000000000000000000000368 108.0
PYH2_k127_1117264_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 478.0
PYH2_k127_1117264_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
PYH2_k127_1117264_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000003889 243.0
PYH2_k127_1117264_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000006914 236.0
PYH2_k127_1117264_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000009197 225.0
PYH2_k127_1117264_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000002441 223.0
PYH2_k127_1117264_8 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000002399 206.0
PYH2_k127_1117264_9 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000001792 175.0
PYH2_k127_1120275_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 5.871e-283 883.0
PYH2_k127_1120275_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 349.0
PYH2_k127_1120275_2 Universal stress protein - - - 0.00000000000000000000000000000001074 133.0
PYH2_k127_1124302_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002035 262.0
PYH2_k127_1124302_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000009301 73.0
PYH2_k127_1125885_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 327.0
PYH2_k127_1125885_1 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000004711 200.0
PYH2_k127_1125885_2 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000007873 120.0
PYH2_k127_112920_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.765e-227 711.0
PYH2_k127_112920_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.006e-205 651.0
PYH2_k127_112920_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000008703 199.0
PYH2_k127_112920_11 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000005325 175.0
PYH2_k127_112920_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000009286 140.0
PYH2_k127_112920_13 Pfam Methyltransferase - - - 0.000000000000000000000000000001072 130.0
PYH2_k127_112920_14 PFAM phosphoesterase, PA-phosphatase related K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.000000003143 67.0
PYH2_k127_112920_15 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000003306 54.0
PYH2_k127_112920_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 482.0
PYH2_k127_112920_3 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 414.0
PYH2_k127_112920_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 385.0
PYH2_k127_112920_5 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 367.0
PYH2_k127_112920_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 327.0
PYH2_k127_112920_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 315.0
PYH2_k127_112920_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 302.0
PYH2_k127_112920_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
PYH2_k127_1133105_0 NADH Ubiquinone plastoquinone (Complex I) K00342,K05568,K12137 - 1.6.5.3 1.181e-215 688.0
PYH2_k127_1133105_1 4Fe-4S dicluster domain K12136 - - 0.0000000000000000000000000000000000000000000000000000134 195.0
PYH2_k127_1133105_2 NADH dehydrogenase K12138 - - 0.00000000000000000000000000000000000000000000000002029 183.0
PYH2_k127_1133105_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000001696 105.0
PYH2_k127_1136882_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 566.0
PYH2_k127_113786_0 Serine carboxypeptidase - - - 1.557e-213 673.0
PYH2_k127_113786_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000001931 183.0
PYH2_k127_113786_2 - - - - 0.00000000000000000000000000000000001799 138.0
PYH2_k127_113786_3 PFAM CBS domain containing protein - - - 0.00000000000001254 74.0
PYH2_k127_1139728_0 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 490.0
PYH2_k127_1139728_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000007845 123.0
PYH2_k127_1158627_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 334.0
PYH2_k127_1158627_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 286.0
PYH2_k127_1158627_2 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000001464 150.0
PYH2_k127_1158627_3 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000003085 129.0
PYH2_k127_1158627_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000318 109.0
PYH2_k127_1163167_0 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 8.383e-270 859.0
PYH2_k127_1163167_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 304.0
PYH2_k127_1163167_2 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 299.0
PYH2_k127_1163167_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001722 285.0
PYH2_k127_1163167_4 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
PYH2_k127_1163167_5 regulation of circadian rhythm K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000001061 241.0
PYH2_k127_1163167_6 - - - - 0.000000000000004901 83.0
PYH2_k127_1163167_7 protein serine/threonine phosphatase activity - - - 0.000002054 61.0
PYH2_k127_1163167_8 protein serine/threonine phosphatase activity - - - 0.0000108 59.0
PYH2_k127_1178830_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 493.0
PYH2_k127_1178830_1 PFAM VanW family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 419.0
PYH2_k127_1178830_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 407.0
PYH2_k127_1178830_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 320.0
PYH2_k127_1178830_4 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 291.0
PYH2_k127_1178830_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000009557 159.0
PYH2_k127_1178830_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000007121 98.0
PYH2_k127_1182923_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000001755 209.0
PYH2_k127_1182923_1 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000007921 193.0
PYH2_k127_1182923_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000006175 162.0
PYH2_k127_1182923_3 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000001121 151.0
PYH2_k127_1182923_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000001484 115.0
PYH2_k127_1191359_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 350.0
PYH2_k127_1191359_1 sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 312.0
PYH2_k127_1191359_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000503 157.0
PYH2_k127_1191359_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000001464 153.0
PYH2_k127_1191359_4 Transposase K07481 - - 0.0000000001465 68.0
PYH2_k127_1191359_5 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.0002839 44.0
PYH2_k127_1191664_0 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 299.0
PYH2_k127_1191664_1 B3 4 domain - - - 0.000000000000000000000000000000000000000009944 164.0
PYH2_k127_119864_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
PYH2_k127_119864_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000005155 75.0
PYH2_k127_119864_2 Glycosyltransferase family 87 - - - 0.0000002658 62.0
PYH2_k127_1199744_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 2.521e-199 629.0
PYH2_k127_1199744_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 437.0
PYH2_k127_1199744_2 Domain present in PSD-95, Dlg, and ZO-1/2. K04771,K08070 - 1.3.1.74,3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003798 291.0
PYH2_k127_1199744_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008906 249.0
PYH2_k127_1199744_4 Monogalactosyldiacylglycerol (MGDG) synthase K03429,K03715 - 2.4.1.315,2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000679 242.0
PYH2_k127_1199744_5 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000001239 193.0
PYH2_k127_1199744_6 FR47-like protein - - - 0.00000000000000000009383 98.0
PYH2_k127_1199744_7 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K02395,K19220,K19223 GO:0005575,GO:0005576 - 0.00000000000001827 85.0
PYH2_k127_1199744_8 photosynthesis - - - 0.0000000004766 70.0
PYH2_k127_120947_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1082.0
PYH2_k127_120947_1 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00002949 57.0
PYH2_k127_1211015_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 337.0
PYH2_k127_1211015_1 LppX_LprAFG lipoprotein K14954 - - 0.0000000000000000000000000000000000000000000003874 175.0
PYH2_k127_1211015_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000006303 158.0
PYH2_k127_1216638_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 461.0
PYH2_k127_1216638_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 346.0
PYH2_k127_1216638_2 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 336.0
PYH2_k127_1216638_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000003842 165.0
PYH2_k127_1216638_4 Protein of unknown function (DUF952) - - - 0.00000000000000000000000001721 112.0
PYH2_k127_1216638_5 phosphate ABC transporter, permease K02038 - - 0.0000000000000000003146 91.0
PYH2_k127_1219720_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 295.0
PYH2_k127_1219720_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009845 252.0
PYH2_k127_1219720_2 - - - - 0.0000000000000000000000000707 114.0
PYH2_k127_1219720_3 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000001508 100.0
PYH2_k127_1227894_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 301.0
PYH2_k127_1227894_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000002248 93.0
PYH2_k127_1229899_0 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 251.0
PYH2_k127_1229899_1 PFAM phospholipase D Transphosphatidylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003201 259.0
PYH2_k127_1229899_2 Lysine exporter protein LysE YggA K06895 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - 0.0000000000000000000000000000000000000000000000000000000000000000002138 235.0
PYH2_k127_1229899_3 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000000000001054 112.0
PYH2_k127_1229899_4 - - - - 0.0000000000000000000000005708 109.0
PYH2_k127_1229899_5 DNA-3-methyladenine glycosylase activity K01246 - 3.2.2.20 0.0000000001636 63.0
PYH2_k127_124858_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 491.0
PYH2_k127_124858_1 III protein, CoA-transferase family K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 395.0
PYH2_k127_124858_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000004633 206.0
PYH2_k127_124858_3 Protein conserved in bacteria - - - 0.00000000000000000000003872 105.0
PYH2_k127_124858_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000585 72.0
PYH2_k127_1257425_0 Metallo-beta-lactamase superfamily domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 493.0
PYH2_k127_1257425_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 487.0
PYH2_k127_1257425_2 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001491 290.0
PYH2_k127_1257425_3 Cytochrome c K17222 - - 0.00000000000000000000000000000000000005903 154.0
PYH2_k127_1257425_4 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000005643 142.0
PYH2_k127_1257425_5 Protein of unknown function (DUF1684) K09164 - - 0.000001627 52.0
PYH2_k127_1262574_0 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000001652 141.0
PYH2_k127_1262574_1 GGDEF domain - - - 0.0000000000000000000000000000007286 133.0
PYH2_k127_1262574_2 Transcriptional regulator crp fnr family - - - 0.0000002179 64.0
PYH2_k127_127180_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.822e-264 835.0
PYH2_k127_127180_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.772e-220 702.0
PYH2_k127_127180_10 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005697 241.0
PYH2_k127_127180_11 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001083 209.0
PYH2_k127_127180_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07673 - 2.7.13.3 0.0000000000000000000000000000004617 137.0
PYH2_k127_127180_13 - - - - 0.0000000000000000000000001198 111.0
PYH2_k127_127180_14 Hemerythrin HHE cation binding domain - - - 0.000000000000000000001903 99.0
PYH2_k127_127180_15 CoA-substrate-specific enzyme activase - - - 0.0000000000001451 72.0
PYH2_k127_127180_16 Domain in cystathionine beta-synthase and other proteins. K14446 - 1.3.1.85 0.00000001649 63.0
PYH2_k127_127180_2 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 482.0
PYH2_k127_127180_3 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 443.0
PYH2_k127_127180_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 414.0
PYH2_k127_127180_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 400.0
PYH2_k127_127180_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 371.0
PYH2_k127_127180_7 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
PYH2_k127_127180_8 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004899 263.0
PYH2_k127_127180_9 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
PYH2_k127_1276374_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 493.0
PYH2_k127_1276374_1 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 318.0
PYH2_k127_1276374_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000001003 61.0
PYH2_k127_1298819_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 392.0
PYH2_k127_1298819_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000001348 138.0
PYH2_k127_1316016_0 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 580.0
PYH2_k127_1316016_1 PFAM magnesium chelatase ChlI subunit K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 416.0
PYH2_k127_1316016_10 sodium ABC transporter, permease K09696 - - 0.0000000000000000000000000000001348 138.0
PYH2_k127_1316016_11 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000007086 134.0
PYH2_k127_1316016_12 membrane - - - 0.00000000000000000000001189 112.0
PYH2_k127_1316016_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000005078 109.0
PYH2_k127_1316016_14 heme binding K21471 - - 0.000000000000000000008272 108.0
PYH2_k127_1316016_15 - - - - 0.00000000000000000002927 98.0
PYH2_k127_1316016_16 PFAM Peptidase M23 - - - 0.000000009867 68.0
PYH2_k127_1316016_2 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 362.0
PYH2_k127_1316016_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 362.0
PYH2_k127_1316016_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 349.0
PYH2_k127_1316016_5 ABC transporter K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003406 280.0
PYH2_k127_1316016_6 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000002286 237.0
PYH2_k127_1316016_7 Nudix hydrolase - - - 0.000000000000000000000000000000000000001826 154.0
PYH2_k127_1316016_8 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000001083 149.0
PYH2_k127_1316016_9 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000005975 132.0
PYH2_k127_1323134_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.361e-238 751.0
PYH2_k127_1323134_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 365.0
PYH2_k127_1323134_10 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000003741 105.0
PYH2_k127_1323134_11 - - - - 0.000000000000000000301 96.0
PYH2_k127_1323134_12 Strong inhibitor of bacterial serine proteases such as subtilisin - - - 0.0006466 48.0
PYH2_k127_1323134_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 346.0
PYH2_k127_1323134_3 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 284.0
PYH2_k127_1323134_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000005946 218.0
PYH2_k127_1323134_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000009514 187.0
PYH2_k127_1323134_6 - - - - 0.00000000000000000000000000000000006237 145.0
PYH2_k127_1323134_7 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.00000000000000000000000000000000007246 142.0
PYH2_k127_1323134_8 acr, cog1399 K07040 - - 0.000000000000000000000000001503 118.0
PYH2_k127_1323134_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000006788 124.0
PYH2_k127_1326287_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1242.0
PYH2_k127_1326287_1 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 334.0
PYH2_k127_1326287_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000002527 239.0
PYH2_k127_1326287_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000001254 234.0
PYH2_k127_1332263_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 480.0
PYH2_k127_1332263_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 440.0
PYH2_k127_1332263_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000003642 218.0
PYH2_k127_1332263_3 Hemerythrin HHE cation binding domain - - - 0.00000009628 60.0
PYH2_k127_1332860_0 LysR substrate binding domain K21703 - - 0.000000000000000000000000000003404 131.0
PYH2_k127_1332860_1 Roadblock/LC7 domain K07131 - - 0.0000000000000001019 85.0
PYH2_k127_1332860_2 cytochrome c biogenesis protein - - - 0.000000000000004291 76.0
PYH2_k127_1341098_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 312.0
PYH2_k127_1341098_1 LamG domain protein jellyroll fold domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000124 299.0
PYH2_k127_1341098_2 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000486 243.0
PYH2_k127_1341098_4 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000002399 217.0
PYH2_k127_1345344_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 288.0
PYH2_k127_1345344_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000005421 164.0
PYH2_k127_1345344_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000003351 74.0
PYH2_k127_1382147_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 4.138e-259 820.0
PYH2_k127_1382147_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 512.0
PYH2_k127_1382147_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 351.0
PYH2_k127_1382147_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004212 220.0
PYH2_k127_1382147_4 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000008357 137.0
PYH2_k127_1382147_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000003519 74.0
PYH2_k127_1382147_6 Acetyltransferase (GNAT) domain - - - 0.00001506 49.0
PYH2_k127_1383120_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 308.0
PYH2_k127_1383120_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 280.0
PYH2_k127_1399648_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1038.0
PYH2_k127_1399648_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 469.0
PYH2_k127_1399648_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 430.0
PYH2_k127_1399648_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 293.0
PYH2_k127_1399648_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000002234 189.0
PYH2_k127_1403494_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 257.0
PYH2_k127_1403494_1 Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000002305 234.0
PYH2_k127_1406603_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 616.0
PYH2_k127_1406603_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000005262 250.0
PYH2_k127_1406603_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000001494 189.0
PYH2_k127_1406603_3 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000009578 162.0
PYH2_k127_1406603_4 single-species biofilm formation K01790,K03806,K06175 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 3.5.1.28,5.1.3.13,5.4.99.26 0.000000000000000000000000000001369 123.0
PYH2_k127_1406603_5 Patatin-like phospholipase - - - 0.0000000003617 65.0
PYH2_k127_1406603_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000934 48.0
PYH2_k127_140925_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1726.0
PYH2_k127_140925_1 D-alanine [D-alanyl carrier protein] ligase activity K03367 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 535.0
PYH2_k127_140925_10 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000007413 185.0
PYH2_k127_140925_11 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K03740 - - 0.00000000000000000000000000005111 131.0
PYH2_k127_140925_12 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000001303 118.0
PYH2_k127_140925_13 belongs to the sigma-70 factor family - - - 0.0000000000000000000006492 108.0
PYH2_k127_140925_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.0000000000000004459 80.0
PYH2_k127_140925_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000004004 80.0
PYH2_k127_140925_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.0000000002126 64.0
PYH2_k127_140925_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 443.0
PYH2_k127_140925_3 TIGRFAM D-alanyl-lipoteichoic acid biosynthesis protein DltB K03739,K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 392.0
PYH2_k127_140925_4 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 372.0
PYH2_k127_140925_5 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 305.0
PYH2_k127_140925_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 310.0
PYH2_k127_140925_7 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007798 289.0
PYH2_k127_140925_8 translation release factor activity K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000001112 242.0
PYH2_k127_140925_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000006726 207.0
PYH2_k127_1410601_0 PFAM glycosyl transferase, family 51 - - - 8.76e-231 738.0
PYH2_k127_1410601_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 292.0
PYH2_k127_1410601_2 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000001084 211.0
PYH2_k127_1410601_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000002876 195.0
PYH2_k127_1410601_4 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000038 164.0
PYH2_k127_1417686_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 400.0
PYH2_k127_1417686_1 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 311.0
PYH2_k127_1417686_2 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000179 100.0
PYH2_k127_143218_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1009.0
PYH2_k127_143218_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000005079 119.0
PYH2_k127_1446249_0 ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 560.0
PYH2_k127_1446249_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000004282 231.0
PYH2_k127_145154_0 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000002266 209.0
PYH2_k127_145154_1 phosphonoacetaldehyde hydrolase activity K05306,K07025,K19270 - 3.1.3.23,3.11.1.1 0.000000000000000000000000000000000000000000001442 171.0
PYH2_k127_145154_2 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000009582 100.0
PYH2_k127_145466_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 617.0
PYH2_k127_145466_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 527.0
PYH2_k127_145466_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000009129 127.0
PYH2_k127_145466_3 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000836 111.0
PYH2_k127_145466_4 Protein conserved in bacteria - - - 0.0000000000001079 76.0
PYH2_k127_145466_5 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0004135 46.0
PYH2_k127_1485587_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 382.0
PYH2_k127_1496412_0 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 328.0
PYH2_k127_1496412_1 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000116 272.0
PYH2_k127_1496412_2 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000004127 234.0
PYH2_k127_1496412_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000008477 180.0
PYH2_k127_1496412_4 Phosphonate ABC transporter K02044 - - 0.0000000000000000000000000001246 128.0
PYH2_k127_150921_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 336.0
PYH2_k127_150921_1 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 310.0
PYH2_k127_150921_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000186 134.0
PYH2_k127_1526686_0 PFAM fumarate lyase K01679 - 4.2.1.2 1.36e-209 661.0
PYH2_k127_1526686_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 310.0
PYH2_k127_1526686_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000002259 239.0
PYH2_k127_1526686_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000007143 175.0
PYH2_k127_1526686_4 FMN binding - - - 0.000000000000000000000000000000000000000000004497 166.0
PYH2_k127_1552929_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 441.0
PYH2_k127_1552929_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000007702 212.0
PYH2_k127_1552929_2 Thioredoxin - - - 0.00000000000000000000000000000000000001459 153.0
PYH2_k127_1571500_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.905e-278 876.0
PYH2_k127_15750_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 336.0
PYH2_k127_15750_1 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000001669 222.0
PYH2_k127_15750_2 transmembrane transporter activity K05820 - - 0.0000000000000000000000000000000000000000000000000000008724 210.0
PYH2_k127_15750_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000000000000000000000000179 201.0
PYH2_k127_15750_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000008192 176.0
PYH2_k127_15750_5 PFAM AIG2 family protein - - - 0.00000000000000000000000000000000000000003118 155.0
PYH2_k127_15750_6 Cupin domain protein - - - 0.00000000000000000000000000000000002687 137.0
PYH2_k127_15750_7 HEAT repeats - - - 0.000000000000000000000000667 112.0
PYH2_k127_158027_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.843e-219 691.0
PYH2_k127_158027_1 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 472.0
PYH2_k127_158027_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 383.0
PYH2_k127_158027_3 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001221 278.0
PYH2_k127_158027_4 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000006485 169.0
PYH2_k127_164020_0 SMART Elongator protein 3 MiaB NifB - - - 2.496e-236 743.0
PYH2_k127_164020_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 544.0
PYH2_k127_164020_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 448.0
PYH2_k127_164020_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K13019 - 5.1.3.23 0.00000000000000000000000001805 111.0
PYH2_k127_164020_4 EamA-like transporter family - - - 0.0000000000000000000000001023 112.0
PYH2_k127_164541_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 489.0
PYH2_k127_164541_1 PFAM YhhN family protein - - - 0.000000000000000000000000000006685 128.0
PYH2_k127_164585_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 520.0
PYH2_k127_1648302_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1244.0
PYH2_k127_1648302_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.723e-312 968.0
PYH2_k127_1648302_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.42e-203 638.0
PYH2_k127_1648302_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000002975 229.0
PYH2_k127_1648302_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000006666 196.0
PYH2_k127_1656983_0 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 533.0
PYH2_k127_1656983_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 482.0
PYH2_k127_1656983_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 375.0
PYH2_k127_1656983_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005676 291.0
PYH2_k127_1656983_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
PYH2_k127_1656983_5 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.000000000000000000000000000000000000000000000000000006172 201.0
PYH2_k127_1656983_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000747 150.0
PYH2_k127_1656983_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000001448 109.0
PYH2_k127_168091_0 Pyruvate kinase, alpha/beta domain K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 458.0
PYH2_k127_168091_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
PYH2_k127_168091_2 PFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006949 267.0
PYH2_k127_168091_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001562 228.0
PYH2_k127_168091_4 DegV family - - - 0.000000000000000000000000000000000000000000000009622 182.0
PYH2_k127_168091_5 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000000000000000000002501 175.0
PYH2_k127_168091_6 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000003485 93.0
PYH2_k127_168091_7 - - - - 0.00000000009947 63.0
PYH2_k127_168091_8 sarcosine oxidase K00306 GO:0003674,GO:0003824,GO:0008115,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016647,GO:0055114 1.5.3.1,1.5.3.7 0.000003965 49.0
PYH2_k127_171444_0 PFAM ABC transporter transmembrane region - - - 4.746e-226 716.0
PYH2_k127_171444_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 6.285e-217 690.0
PYH2_k127_171444_2 - - - - 0.0000000000000000000000000000009292 126.0
PYH2_k127_171444_4 Belongs to the peptidase M50B family - - - 0.0000000001237 68.0
PYH2_k127_1771618_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 276.0
PYH2_k127_1771618_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000001176 73.0
PYH2_k127_1771618_2 anaphase-promoting complex binding - - - 0.00001211 54.0
PYH2_k127_1802994_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.786e-312 974.0
PYH2_k127_1802994_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 326.0
PYH2_k127_1802994_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003258 247.0
PYH2_k127_1802994_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00007547 49.0
PYH2_k127_1810444_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 437.0
PYH2_k127_1810444_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 294.0
PYH2_k127_1810444_10 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000324 57.0
PYH2_k127_1810444_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000006502 249.0
PYH2_k127_1810444_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
PYH2_k127_1810444_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
PYH2_k127_1810444_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000008251 190.0
PYH2_k127_1810444_6 Major facilitator superfamily - - - 0.0000000000000000001625 94.0
PYH2_k127_1810444_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000008523 82.0
PYH2_k127_1810444_8 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000002171 64.0
PYH2_k127_1827278_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 9.685e-265 819.0
PYH2_k127_1827278_1 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 391.0
PYH2_k127_183498_0 Histidine kinase-like ATPases - - - 8.476e-222 716.0
PYH2_k127_183498_1 Tetratricopeptide repeat - - - 0.000000000000000000000000007578 127.0
PYH2_k127_1842785_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001026 232.0
PYH2_k127_1842785_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000009828 178.0
PYH2_k127_1842785_2 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000009913 175.0
PYH2_k127_1842785_3 Glycosyltransferase, group 1 family protein K19002 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 0.00000000000000000000000000000984 133.0
PYH2_k127_1842785_4 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000003157 87.0
PYH2_k127_1864001_0 ATPase ArsA K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 269.0
PYH2_k127_1864001_1 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000002282 179.0
PYH2_k127_1864001_2 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000000000000000000001726 160.0
PYH2_k127_1864001_3 Putative Fe-S cluster - - - 0.0000000000000000000000000000000000005173 145.0
PYH2_k127_1864001_4 Putative Fe-S cluster - - - 0.000000000000000000000000002846 117.0
PYH2_k127_1864001_5 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000005308 105.0
PYH2_k127_1864001_6 Thioredoxin domain - - - 0.00000000000000000000007063 100.0
PYH2_k127_1883529_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000001706 251.0
PYH2_k127_1883529_1 - - - - 0.00000000000000000000000000000001035 138.0
PYH2_k127_1883529_2 Bacterial DNA-binding protein - - - 0.0000000000000000000003567 99.0
PYH2_k127_1883529_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000006049 82.0
PYH2_k127_1886805_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1091.0
PYH2_k127_1886805_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 491.0
PYH2_k127_1886805_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000009007 187.0
PYH2_k127_1886805_11 Transcriptional regulatory protein, C terminal - - - 0.000000000000000007644 83.0
PYH2_k127_1886805_13 POTRA domain, FtsQ-type K03589 - - 0.000000001254 68.0
PYH2_k127_1886805_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 446.0
PYH2_k127_1886805_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 441.0
PYH2_k127_1886805_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 421.0
PYH2_k127_1886805_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 409.0
PYH2_k127_1886805_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 327.0
PYH2_k127_1886805_7 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000005146 262.0
PYH2_k127_1886805_8 TIGRFAM cell division protein FtsW K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000898 266.0
PYH2_k127_1886805_9 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000007218 232.0
PYH2_k127_1906554_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000002491 160.0
PYH2_k127_1906554_1 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000009324 168.0
PYH2_k127_1906554_2 Signal transduction histidine kinase - - - 0.00000007964 65.0
PYH2_k127_1906554_3 transmembrane signaling receptor activity K03406 - - 0.000005534 57.0
PYH2_k127_190840_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000001757 202.0
PYH2_k127_190840_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000004907 63.0
PYH2_k127_1909722_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 495.0
PYH2_k127_1909722_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000002466 160.0
PYH2_k127_1909722_2 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000001352 146.0
PYH2_k127_1909722_3 Methyltransferase domain - - - 0.000000000000000000000000000000004542 136.0
PYH2_k127_1909722_4 Protein of unknown function (DUF983) - - - 0.000000000000000000000002026 106.0
PYH2_k127_1909722_5 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000001273 72.0
PYH2_k127_1909722_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000006968 57.0
PYH2_k127_1927490_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 411.0
PYH2_k127_1927490_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000002631 142.0
PYH2_k127_1927490_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001202 138.0
PYH2_k127_1927490_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000003811 139.0
PYH2_k127_1927490_4 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000002453 132.0
PYH2_k127_1927490_5 EamA-like transporter family - - - 0.000000005712 57.0
PYH2_k127_1927490_6 PFAM ABC transporter K01990 - - 0.0009538 45.0
PYH2_k127_1937135_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000009216 153.0
PYH2_k127_1937135_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000001249 89.0
PYH2_k127_1943706_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 509.0
PYH2_k127_1943706_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 407.0
PYH2_k127_1943706_2 Serine threonine protein kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 391.0
PYH2_k127_1943706_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004632 233.0
PYH2_k127_1943706_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000001352 210.0
PYH2_k127_1943706_5 Methyltransferase domain - - - 0.00000000000000000000000000001374 128.0
PYH2_k127_1943706_6 transposase activity K07495 - - 0.000000000000000002809 87.0
PYH2_k127_1943706_7 transposase activity K07495 - - 0.000000000000001287 77.0
PYH2_k127_1943706_8 Protein of unknown function (DUF1706) - - - 0.0003288 50.0
PYH2_k127_1943706_9 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.0009086 50.0
PYH2_k127_1952714_0 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 342.0
PYH2_k127_1952714_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000384 278.0
PYH2_k127_1952714_2 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000001668 252.0
PYH2_k127_1952714_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000003487 207.0
PYH2_k127_196410_0 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0 1032.0
PYH2_k127_196410_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 495.0
PYH2_k127_196410_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 489.0
PYH2_k127_196410_3 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 405.0
PYH2_k127_196410_4 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001318 280.0
PYH2_k127_196410_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002997 254.0
PYH2_k127_196410_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000001994 190.0
PYH2_k127_196410_7 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000267 126.0
PYH2_k127_196410_8 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000002247 111.0
PYH2_k127_196410_9 Domain of unknown function (DUF4129) - - - 0.0000000000000000001171 104.0
PYH2_k127_1985855_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 464.0
PYH2_k127_1985855_1 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 323.0
PYH2_k127_2000245_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.404e-291 922.0
PYH2_k127_2000245_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 544.0
PYH2_k127_2000245_10 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000000000005895 191.0
PYH2_k127_2000245_11 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000898 186.0
PYH2_k127_2000245_12 PFAM Integrase core domain K07497 - - 0.00000000000000000000000000006097 118.0
PYH2_k127_2000245_13 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000001012 113.0
PYH2_k127_2000245_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.00000000000000000000002024 113.0
PYH2_k127_2000245_15 PFAM Integrase core domain K07497 - - 0.00000000000000000003913 91.0
PYH2_k127_2000245_16 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000002989 89.0
PYH2_k127_2000245_17 - - - - 0.000000000007061 72.0
PYH2_k127_2000245_19 SPTR B0JRC2 Transposase - - - 0.00000000002473 69.0
PYH2_k127_2000245_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 536.0
PYH2_k127_2000245_20 Ricin-type beta-trefoil K21104 - 3.1.1.101 0.00000000006934 75.0
PYH2_k127_2000245_21 - - - - 0.00000000007788 74.0
PYH2_k127_2000245_22 COG2963 Transposase and inactivated derivatives K07483 - - 0.000000005181 59.0
PYH2_k127_2000245_23 HNH endonuclease - - - 0.000001224 55.0
PYH2_k127_2000245_3 PFAM Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 336.0
PYH2_k127_2000245_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
PYH2_k127_2000245_5 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001017 303.0
PYH2_k127_2000245_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002192 268.0
PYH2_k127_2000245_7 Phosphate transporter family protein K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005748 260.0
PYH2_k127_2000245_8 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003971 263.0
PYH2_k127_2000245_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000005637 196.0
PYH2_k127_2006160_0 (ABC) transporter K06147 - - 2.085e-230 727.0
PYH2_k127_2006160_1 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 476.0
PYH2_k127_2006160_2 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003738 284.0
PYH2_k127_2006160_3 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 280.0
PYH2_k127_2006160_4 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000428 133.0
PYH2_k127_2006160_5 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000009556 104.0
PYH2_k127_2007582_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 297.0
PYH2_k127_2007582_1 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002472 247.0
PYH2_k127_2007582_2 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003372 247.0
PYH2_k127_2007582_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000001077 162.0
PYH2_k127_2016657_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1133.0
PYH2_k127_2016657_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 278.0
PYH2_k127_2016657_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000007653 50.0
PYH2_k127_2026924_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 1.498e-250 786.0
PYH2_k127_2026924_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003787 244.0
PYH2_k127_2026924_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000001926 80.0
PYH2_k127_2048299_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 505.0
PYH2_k127_2048299_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
PYH2_k127_2048299_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000198 204.0
PYH2_k127_2048299_3 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000001635 132.0
PYH2_k127_2061291_0 PFAM ABC transporter transmembrane region K06147 - - 9.767e-253 795.0
PYH2_k127_2061291_1 PFAM ABC transporter transmembrane region K06147 - - 9.604e-248 781.0
PYH2_k127_2061291_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 449.0
PYH2_k127_2061291_11 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 442.0
PYH2_k127_2061291_12 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 439.0
PYH2_k127_2061291_13 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 438.0
PYH2_k127_2061291_14 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 414.0
PYH2_k127_2061291_15 ABC-3 protein K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 384.0
PYH2_k127_2061291_16 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 356.0
PYH2_k127_2061291_17 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 363.0
PYH2_k127_2061291_18 PFAM ABC transporter related K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 349.0
PYH2_k127_2061291_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 333.0
PYH2_k127_2061291_2 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 9.723e-241 757.0
PYH2_k127_2061291_20 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 326.0
PYH2_k127_2061291_21 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 321.0
PYH2_k127_2061291_22 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 329.0
PYH2_k127_2061291_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
PYH2_k127_2061291_24 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000007503 245.0
PYH2_k127_2061291_25 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
PYH2_k127_2061291_26 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000004205 239.0
PYH2_k127_2061291_27 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000002177 216.0
PYH2_k127_2061291_28 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000005088 214.0
PYH2_k127_2061291_29 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000005806 190.0
PYH2_k127_2061291_3 PFAM glycosyl transferase, family 51 - - - 6.139e-237 767.0
PYH2_k127_2061291_30 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000002704 184.0
PYH2_k127_2061291_31 - - - - 0.00000000000000000000000000000000000547 138.0
PYH2_k127_2061291_32 - - - - 0.0000000000000000000000000008549 114.0
PYH2_k127_2061291_33 Ferric uptake regulator family K03711 - - 0.000000000000000000000000001718 117.0
PYH2_k127_2061291_34 - - - - 0.0000000000000000000000002714 107.0
PYH2_k127_2061291_35 acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000001314 114.0
PYH2_k127_2061291_36 succinate dehydrogenase K00241 - - 0.0000000000000000000004109 107.0
PYH2_k127_2061291_37 PFAM regulatory protein TetR - - - 0.0000000000000000000008835 102.0
PYH2_k127_2061291_38 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.00000000000000005079 92.0
PYH2_k127_2061291_39 - - - - 0.0000000000001291 73.0
PYH2_k127_2061291_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 604.0
PYH2_k127_2061291_40 - - - - 0.00000001805 64.0
PYH2_k127_2061291_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 589.0
PYH2_k127_2061291_6 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 567.0
PYH2_k127_2061291_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 565.0
PYH2_k127_2061291_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 507.0
PYH2_k127_2061291_9 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 449.0
PYH2_k127_2061299_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 511.0
PYH2_k127_2061299_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000003482 221.0
PYH2_k127_2061299_2 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.00000000000001168 76.0
PYH2_k127_2064376_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 408.0
PYH2_k127_2069010_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 578.0
PYH2_k127_2069010_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 437.0
PYH2_k127_2069010_2 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 370.0
PYH2_k127_2069010_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
PYH2_k127_2069010_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000001223 119.0
PYH2_k127_2069010_5 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000002296 62.0
PYH2_k127_2069010_6 ABC transporter K02027 - - 0.00001091 57.0
PYH2_k127_2069010_7 signal peptide processing K13280 - 3.4.21.89 0.00001535 53.0
PYH2_k127_2069010_8 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00007403 48.0
PYH2_k127_2075260_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 1.372e-219 704.0
PYH2_k127_2075260_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 588.0
PYH2_k127_2075260_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000001356 134.0
PYH2_k127_2075260_11 -acetyltransferase - - - 0.000000000000000000000000000000003001 139.0
PYH2_k127_2075260_12 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000002368 117.0
PYH2_k127_2075260_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000007347 115.0
PYH2_k127_2075260_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000008144 92.0
PYH2_k127_2075260_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 496.0
PYH2_k127_2075260_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 388.0
PYH2_k127_2075260_4 Acetyltransferase (Isoleucine patch superfamily) K18234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 321.0
PYH2_k127_2075260_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 327.0
PYH2_k127_2075260_6 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 314.0
PYH2_k127_2075260_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000000000000001457 179.0
PYH2_k127_2075260_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000003656 169.0
PYH2_k127_2075260_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000008765 145.0
PYH2_k127_2091849_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 454.0
PYH2_k127_2091849_1 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 369.0
PYH2_k127_2096592_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 304.0
PYH2_k127_2113758_0 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 539.0
PYH2_k127_2113758_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000001191 209.0
PYH2_k127_2113758_2 PFAM O-antigen polymerase - - - 0.000000000000000000000000000000000000000000000000000000001528 219.0
PYH2_k127_2113758_3 GtrA-like protein - - - 0.00000000000000000000000002037 114.0
PYH2_k127_2113758_4 GtrA-like protein - - - 0.0000000000000000000005891 98.0
PYH2_k127_2113758_5 Methyltransferase type 11 - - - 0.00000000000000000006483 96.0
PYH2_k127_213867_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 548.0
PYH2_k127_213867_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 379.0
PYH2_k127_213867_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 361.0
PYH2_k127_213867_3 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 302.0
PYH2_k127_2161060_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.36e-316 996.0
PYH2_k127_2161060_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 572.0
PYH2_k127_2161060_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006937 241.0
PYH2_k127_2161060_11 CpXC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 246.0
PYH2_k127_2161060_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002759 178.0
PYH2_k127_2161060_13 Baseplate J-like protein K01218 - 3.2.1.78 0.0000000000000000000000000000000000000002111 168.0
PYH2_k127_2161060_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000002167 122.0
PYH2_k127_2161060_15 Acetyltransferase (GNAT) family - - - 0.00000000000000000000009624 105.0
PYH2_k127_2161060_16 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000891 87.0
PYH2_k127_2161060_17 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000001066 81.0
PYH2_k127_2161060_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 516.0
PYH2_k127_2161060_3 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 448.0
PYH2_k127_2161060_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 409.0
PYH2_k127_2161060_5 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 294.0
PYH2_k127_2161060_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 297.0
PYH2_k127_2161060_7 Periplasmic binding protein domain K10546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 284.0
PYH2_k127_2161060_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001252 253.0
PYH2_k127_2161060_9 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000002661 246.0
PYH2_k127_2176454_0 Metallo-beta-lactamase superfamily domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 493.0
PYH2_k127_2180243_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 325.0
PYH2_k127_2180243_1 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000252 266.0
PYH2_k127_2180243_2 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000007242 214.0
PYH2_k127_2180243_3 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000001224 128.0
PYH2_k127_2180243_4 Transmembrane anti-sigma factor - - - 0.000000000000000000003089 94.0
PYH2_k127_2180243_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000001942 72.0
PYH2_k127_2180243_6 Protein of unknown function (DUF2721) - - - 0.000000000002089 75.0
PYH2_k127_2205828_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 591.0
PYH2_k127_2205828_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 434.0
PYH2_k127_2205828_2 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 356.0
PYH2_k127_2205828_3 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 269.0
PYH2_k127_2205828_4 TIGRFAM primosome, DnaD subunit - - - 0.000000000000000000000006276 110.0
PYH2_k127_2245789_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000001643 186.0
PYH2_k127_2245789_1 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000000000000001235 148.0
PYH2_k127_2245789_2 domain protein K02005,K06006,K07803,K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000002656 102.0
PYH2_k127_2260488_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004904 291.0
PYH2_k127_2291791_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 352.0
PYH2_k127_2291791_1 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000004683 269.0
PYH2_k127_2291791_2 Enoyl-CoA hydratase/isomerase K13767,K13816 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000001264 233.0
PYH2_k127_2291791_3 phosphoesterase, PA-phosphatase related - - - 0.00000000000000001278 90.0
PYH2_k127_2291791_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000343 53.0
PYH2_k127_2293784_0 radical SAM domain protein - - - 1.949e-237 740.0
PYH2_k127_2293784_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 2.962e-198 629.0
PYH2_k127_2293784_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 317.0
PYH2_k127_2293784_3 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.000000000000000000000000000000000001846 143.0
PYH2_k127_2293784_4 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000001493 141.0
PYH2_k127_2293784_5 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000004098 121.0
PYH2_k127_2293784_7 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000887 73.0
PYH2_k127_2331375_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.86e-205 658.0
PYH2_k127_2331375_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000003662 221.0
PYH2_k127_2331375_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000004102 220.0
PYH2_k127_2331375_3 2Fe-2S -binding domain K03518,K18022 - 1.2.5.3,1.2.99.8 0.000000000000000000000000000000000000000000000000000005546 194.0
PYH2_k127_2331375_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000001632 127.0
PYH2_k127_235523_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 580.0
PYH2_k127_235523_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
PYH2_k127_235523_2 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000006618 239.0
PYH2_k127_235523_3 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000000000000000000000000000000000000000000000009909 224.0
PYH2_k127_235523_4 UTRA K03710 - - 0.000000000000000000000000000000000000000000000006183 181.0
PYH2_k127_235523_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000001137 141.0
PYH2_k127_235523_6 PTS system mannose/fructose/sorbose family IID component - - - 0.0000000000000000000000000000944 119.0
PYH2_k127_235523_7 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000000001386 97.0
PYH2_k127_2361078_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1220.0
PYH2_k127_2361078_1 -acetyltransferase - - - 0.0000000000000000000000126 102.0
PYH2_k127_2361078_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000007623 86.0
PYH2_k127_2400566_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000003033 154.0
PYH2_k127_2400566_1 Membrane - - - 0.000000000000007212 81.0
PYH2_k127_2400742_0 ATPase AAA-2 domain protein K03696 - - 0.0 1078.0
PYH2_k127_2400742_1 Protein of unknown function, DUF255 K06888 - - 2.813e-226 722.0
PYH2_k127_2400742_10 Prephenate dehydrogenase K00210,K00220,K04517 - 1.3.1.12,1.3.1.43 0.0000000000000000000000000000001245 136.0
PYH2_k127_2400742_11 endonuclease containing a URI domain K07461 - - 0.00000000000000000000003284 101.0
PYH2_k127_2400742_12 PFAM regulatory protein GntR HTH K07979 - - 0.0000000000000000000004974 100.0
PYH2_k127_2400742_13 ABC-2 family transporter protein - - - 0.000000000000002931 79.0
PYH2_k127_2400742_14 PFAM HD domain - - - 0.000000000000008691 83.0
PYH2_k127_2400742_2 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 493.0
PYH2_k127_2400742_3 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 464.0
PYH2_k127_2400742_4 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 396.0
PYH2_k127_2400742_5 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 348.0
PYH2_k127_2400742_6 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 343.0
PYH2_k127_2400742_7 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003283 265.0
PYH2_k127_2400742_8 Peptidase M50 - - - 0.0000000000000000000000000000000000000005508 156.0
PYH2_k127_2400742_9 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000003023 151.0
PYH2_k127_240097_0 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 444.0
PYH2_k127_240097_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 388.0
PYH2_k127_240097_2 - - - - 0.000000000000000000000000001725 115.0
PYH2_k127_240097_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000001049 88.0
PYH2_k127_241965_0 nitrate reductase beta subunit K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 1.247e-223 698.0
PYH2_k127_241965_1 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000000000000000000000000000004256 239.0
PYH2_k127_241965_2 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000004575 206.0
PYH2_k127_241965_3 protein complex oligomerization - - - 0.0000000000000000000000000000000000000000000000000001362 196.0
PYH2_k127_241965_4 - - - - 0.00000000000000000000000000000000000000000000000002972 190.0
PYH2_k127_2461664_0 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000109 285.0
PYH2_k127_2461664_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000003484 216.0
PYH2_k127_2461664_2 carboxylic ester hydrolase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000006853 139.0
PYH2_k127_2461664_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000002604 114.0
PYH2_k127_2461664_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K18917 - 1.20.4.3 0.0000000000003154 74.0
PYH2_k127_2476603_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.677e-208 659.0
PYH2_k127_2476603_1 - - - - 0.00001063 51.0
PYH2_k127_2479740_0 GXGXG motif - - - 3.476e-264 838.0
PYH2_k127_2479740_1 Glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 599.0
PYH2_k127_2479740_2 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 423.0
PYH2_k127_2479740_3 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000214 104.0
PYH2_k127_249851_0 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000132 194.0
PYH2_k127_249851_1 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000008558 193.0
PYH2_k127_249851_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000215 161.0
PYH2_k127_249851_3 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000000000000000000005577 140.0
PYH2_k127_249851_4 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000001421 117.0
PYH2_k127_249851_6 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000002423 58.0
PYH2_k127_2527450_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 361.0
PYH2_k127_2527450_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000001527 148.0
PYH2_k127_2527450_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000003352 144.0
PYH2_k127_2562343_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 405.0
PYH2_k127_2562343_1 Ribonucleotide reductase, small chain K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009124 257.0
PYH2_k127_2562343_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000003829 196.0
PYH2_k127_2562343_3 EthD domain - - - 0.000000000000000000000000000000001141 132.0
PYH2_k127_257850_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000003104 216.0
PYH2_k127_257850_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000002326 55.0
PYH2_k127_257955_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.139e-292 912.0
PYH2_k127_257955_1 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000003123 237.0
PYH2_k127_257955_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000001824 222.0
PYH2_k127_257955_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000003186 201.0
PYH2_k127_257955_4 - - - - 0.0000000000000004969 84.0
PYH2_k127_257955_5 OsmC-like protein - - - 0.000000000000005079 76.0
PYH2_k127_257955_6 Uncharacterized ACR, COG1430 K09005 - - 0.000002126 54.0
PYH2_k127_2581113_0 Aminotransferase class-V K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 306.0
PYH2_k127_2581113_2 protein homooligomerization - - - 0.000000004419 62.0
PYH2_k127_2581113_3 photosynthesis K02656 - - 0.00000007401 64.0
PYH2_k127_2614562_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1050.0
PYH2_k127_2681354_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 461.0
PYH2_k127_269330_0 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000005442 217.0
PYH2_k127_269330_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000006366 150.0
PYH2_k127_270238_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 582.0
PYH2_k127_270238_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000002973 239.0
PYH2_k127_270238_2 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000002634 175.0
PYH2_k127_270238_3 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000004565 178.0
PYH2_k127_275664_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 524.0
PYH2_k127_275664_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 340.0
PYH2_k127_275664_2 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 299.0
PYH2_k127_275664_3 6-phospho-beta-galactosidase activity - - - 0.00000000000000000000009581 113.0
PYH2_k127_275664_6 L-allo-threonine aldolase activity - - - 0.000003068 51.0
PYH2_k127_275664_7 TIGRFAM phosphate binding protein K02040 - - 0.00003926 48.0
PYH2_k127_2785328_0 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 3.11e-302 954.0
PYH2_k127_2785328_1 Belongs to the glycosyl hydrolase 31 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 523.0
PYH2_k127_2785328_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 452.0
PYH2_k127_2785328_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 457.0
PYH2_k127_2785328_4 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 440.0
PYH2_k127_2785328_5 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 309.0
PYH2_k127_2785328_6 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000007906 248.0
PYH2_k127_2785328_7 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000004956 231.0
PYH2_k127_2785328_8 PFAM extracellular solute-binding protein family 1 K02027 - - 0.00000000000000000000000000000634 122.0
PYH2_k127_2785328_9 transferase activity, transferring glycosyl groups - - - 0.000002738 50.0
PYH2_k127_2806840_0 Belongs to the carbamoyltransferase HypF family K04656 - - 7.041e-209 666.0
PYH2_k127_2806840_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 533.0
PYH2_k127_2806840_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 477.0
PYH2_k127_2806840_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000000846 117.0
PYH2_k127_2806840_4 Belongs to the peptidase S8 family K13274,K14645 - - 0.00000000000000000000002724 111.0
PYH2_k127_2809338_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000001434 204.0
PYH2_k127_2809338_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000006982 56.0
PYH2_k127_2809338_2 phosphorelay signal transduction system - - - 0.0001385 46.0
PYH2_k127_2839437_0 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003381 276.0
PYH2_k127_2839437_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000002162 101.0
PYH2_k127_2839437_3 - - - - 0.00000000000001607 85.0
PYH2_k127_2839722_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000001276 122.0
PYH2_k127_2839722_1 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000001963 112.0
PYH2_k127_2839722_2 spore germination K03605 - - 0.000000000000000002048 91.0
PYH2_k127_2839722_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000003043 85.0
PYH2_k127_2844019_0 AAA ATPase domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 349.0
PYH2_k127_2857264_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 449.0
PYH2_k127_2857264_1 phosphorelay signal transduction system K01768,K19622 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 338.0
PYH2_k127_2857264_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 303.0
PYH2_k127_2857264_3 cellulase activity K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005663 284.0
PYH2_k127_2857264_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000002386 256.0
PYH2_k127_2857264_5 PFAM peptidase S16 lon domain protein K07157 - - 0.0000000000000000000000000000000001204 141.0
PYH2_k127_2857264_6 - - - - 0.0000000000000000000000000004008 123.0
PYH2_k127_2876279_0 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 612.0
PYH2_k127_2876279_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 436.0
PYH2_k127_2876279_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 403.0
PYH2_k127_2876279_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 383.0
PYH2_k127_2876279_4 ABC-type dipeptide oligopeptide nickel transport systems, permease K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 338.0
PYH2_k127_2876279_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 348.0
PYH2_k127_2876279_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
PYH2_k127_2876279_7 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000007027 235.0
PYH2_k127_2876279_8 Fibronectin type 3 domain - - - 0.0007416 52.0
PYH2_k127_287822_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000001254 202.0
PYH2_k127_287822_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000001334 146.0
PYH2_k127_2885426_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 325.0
PYH2_k127_2885426_1 Protein of unknown function (DUF3352) - - - 0.000006415 58.0
PYH2_k127_2891640_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 369.0
PYH2_k127_2891640_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000005441 248.0
PYH2_k127_2891640_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000007217 236.0
PYH2_k127_2909276_0 PFAM type II secretion system protein E K02283 - - 1.681e-206 651.0
PYH2_k127_2909276_1 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 354.0
PYH2_k127_2925793_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 453.0
PYH2_k127_2925793_1 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000001135 120.0
PYH2_k127_2925793_2 - - - - 0.0000000000002075 74.0
PYH2_k127_2925793_3 spectrin binding K19044 GO:0003674,GO:0003824,GO:0004842,GO:0006464,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0032446,GO:0036211,GO:0042742,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051704,GO:0051707,GO:0051865,GO:0070647,GO:0071704,GO:0098542,GO:0140096,GO:1901564 2.3.2.27 0.00003317 47.0
PYH2_k127_2933378_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.326e-245 777.0
PYH2_k127_2933378_1 Aminotransferase class-V K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 561.0
PYH2_k127_2933378_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 289.0
PYH2_k127_2933378_11 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001725 261.0
PYH2_k127_2933378_12 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005933 269.0
PYH2_k127_2933378_13 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000015 259.0
PYH2_k127_2933378_14 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000001011 241.0
PYH2_k127_2933378_15 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000002768 241.0
PYH2_k127_2933378_16 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000008675 237.0
PYH2_k127_2933378_17 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000004504 229.0
PYH2_k127_2933378_18 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000009599 236.0
PYH2_k127_2933378_19 binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000001391 231.0
PYH2_k127_2933378_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 411.0
PYH2_k127_2933378_20 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000985 180.0
PYH2_k127_2933378_21 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000191 172.0
PYH2_k127_2933378_22 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000419 135.0
PYH2_k127_2933378_23 RF-1 domain K15034 - - 0.00000000000000000000000000002736 122.0
PYH2_k127_2933378_24 phosphohistidine phosphatase, SixA K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000003607 112.0
PYH2_k127_2933378_25 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000299 96.0
PYH2_k127_2933378_26 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000906 93.0
PYH2_k127_2933378_27 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000001054 55.0
PYH2_k127_2933378_28 thiamine diphosphate biosynthetic process K03154 - - 0.00004313 48.0
PYH2_k127_2933378_29 triphosphatase activity K18446 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.1.25 0.00005225 56.0
PYH2_k127_2933378_3 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 406.0
PYH2_k127_2933378_30 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0003116 44.0
PYH2_k127_2933378_4 Haloacid dehalogenase-like hydrolase K02566 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 351.0
PYH2_k127_2933378_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 357.0
PYH2_k127_2933378_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 351.0
PYH2_k127_2933378_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 318.0
PYH2_k127_2933378_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 322.0
PYH2_k127_2933378_9 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 313.0
PYH2_k127_2941263_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.876e-212 675.0
PYH2_k127_2941263_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 402.0
PYH2_k127_2941263_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 365.0
PYH2_k127_2941263_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000002465 201.0
PYH2_k127_2950188_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000008418 223.0
PYH2_k127_2950188_1 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000004421 170.0
PYH2_k127_2950188_2 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000003996 88.0
PYH2_k127_2951735_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004827 246.0
PYH2_k127_2951735_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001045 221.0
PYH2_k127_2951735_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000003373 175.0
PYH2_k127_2951735_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000001794 168.0
PYH2_k127_2951735_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000001533 164.0
PYH2_k127_2951735_5 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000006507 141.0
PYH2_k127_2960580_0 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 526.0
PYH2_k127_2960580_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000211 220.0
PYH2_k127_2960580_2 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000001678 200.0
PYH2_k127_2960580_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000001089 167.0
PYH2_k127_2960580_4 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K02759,K03478 - 2.7.1.196,2.7.1.205,3.5.1.105 0.0000000000000000000000000000000000000000436 162.0
PYH2_k127_2960580_5 Protein of unknown function (DUF3467) - - - 0.000000000000000007107 88.0
PYH2_k127_2960580_6 - - - - 0.0002559 46.0
PYH2_k127_2962455_0 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
PYH2_k127_2962455_1 PFAM peptidylprolyl isomerase FKBP-type K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001168 192.0
PYH2_k127_2962455_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000006695 107.0
PYH2_k127_29723_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 404.0
PYH2_k127_29723_1 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
PYH2_k127_2974273_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 445.0
PYH2_k127_2974273_1 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001974 277.0
PYH2_k127_2974273_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000002316 254.0
PYH2_k127_2974273_3 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000002215 156.0
PYH2_k127_2974273_4 Forkhead associated domain - - - 0.000000000000000002267 91.0
PYH2_k127_2974273_5 Protein of unknown function (DUF1706) - - - 0.0000000001928 68.0
PYH2_k127_2978771_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 306.0
PYH2_k127_2978771_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
PYH2_k127_2978771_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.0000000000000000000123 94.0
PYH2_k127_2978771_3 His Kinase A (phosphoacceptor) domain - - - 0.0007178 45.0
PYH2_k127_298176_0 transport system K01992 - - 1.273e-249 802.0
PYH2_k127_298176_1 spermidine synthase activity - - - 2.436e-233 734.0
PYH2_k127_298176_2 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 346.0
PYH2_k127_298176_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 339.0
PYH2_k127_298176_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 279.0
PYH2_k127_298176_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001592 268.0
PYH2_k127_298176_6 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000000000000006717 155.0
PYH2_k127_298176_7 Domain of unknown function (DUF4340) - - - 0.000001155 60.0
PYH2_k127_2987160_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 404.0
PYH2_k127_2987160_1 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000002571 239.0
PYH2_k127_2987160_2 4Fe-4S binding domain K07307,K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000002444 235.0
PYH2_k127_2987160_3 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000000000000107 176.0
PYH2_k127_2987160_4 Cytochrome b subunit of the bc K00412,K02635 - - 0.000001475 55.0
PYH2_k127_299541_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 385.0
PYH2_k127_299541_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002541 236.0
PYH2_k127_299541_2 Glycosyl transferase 4-like domain - - - 0.0000001026 58.0
PYH2_k127_3022362_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 552.0
PYH2_k127_3022362_1 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000000000000000000000000028 201.0
PYH2_k127_3022362_2 Rdx family K07401 - - 0.0000000000003316 71.0
PYH2_k127_3054143_0 PFAM AAA-4 family protein K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 481.0
PYH2_k127_3054143_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 329.0
PYH2_k127_3054143_2 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001726 259.0
PYH2_k127_3060681_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.628e-239 762.0
PYH2_k127_3060681_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 320.0
PYH2_k127_3060681_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 320.0
PYH2_k127_313884_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1415.0
PYH2_k127_313884_1 Aromatic amino acid lyase K01745 - 4.3.1.3 1.81e-253 789.0
PYH2_k127_313884_10 Cell division protein FtsI penicillin-binding protein 2 K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000002658 76.0
PYH2_k127_313884_11 KR domain K07124 - - 0.00000000002648 70.0
PYH2_k127_313884_12 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000264 66.0
PYH2_k127_313884_2 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 607.0
PYH2_k127_313884_3 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 564.0
PYH2_k127_313884_4 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 494.0
PYH2_k127_313884_5 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 378.0
PYH2_k127_313884_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 350.0
PYH2_k127_313884_7 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 307.0
PYH2_k127_313884_8 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 296.0
PYH2_k127_313884_9 Pseudouridine synthase K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000004962 206.0
PYH2_k127_3142474_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 442.0
PYH2_k127_3142474_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 420.0
PYH2_k127_3152772_0 PFAM ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 326.0
PYH2_k127_3152772_1 PFAM alpha amylase catalytic region K05343 - 3.2.1.1,5.4.99.16 0.00002691 50.0
PYH2_k127_3153478_0 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 609.0
PYH2_k127_3153478_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 455.0
PYH2_k127_3153478_2 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000003316 267.0
PYH2_k127_3153478_3 HD domain K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003451 256.0
PYH2_k127_3153478_4 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000007365 204.0
PYH2_k127_3153478_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000002587 198.0
PYH2_k127_3153478_6 CoA carboxylase activity K01965 - 6.4.1.3 0.000000000000000000000000000009202 124.0
PYH2_k127_3170060_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.4e-205 656.0
PYH2_k127_3170060_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 500.0
PYH2_k127_3170060_2 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 328.0
PYH2_k127_3170060_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000002478 142.0
PYH2_k127_3170060_4 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000005204 138.0
PYH2_k127_3170060_5 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000003888 141.0
PYH2_k127_3170060_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0005921 45.0
PYH2_k127_3232550_0 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000003494 185.0
PYH2_k127_3232550_1 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000000007377 141.0
PYH2_k127_3232550_2 Ig-like domain from next to BRCA1 gene - GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - 0.0005343 53.0
PYH2_k127_3255573_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.411e-264 834.0
PYH2_k127_3255573_1 Belongs to the RtcB family K14415 - 6.5.1.3 2.164e-206 649.0
PYH2_k127_3255573_2 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 298.0
PYH2_k127_3255573_3 methyltransferase - - - 0.0000000000000000000000000000005169 130.0
PYH2_k127_3255573_4 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000001566 128.0
PYH2_k127_3271218_0 oligosaccharyl transferase activity - - - 0.00000000000000000000000826 117.0
PYH2_k127_3271218_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000001935 90.0
PYH2_k127_3271218_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000003897 62.0
PYH2_k127_3293284_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 545.0
PYH2_k127_3293284_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 304.0
PYH2_k127_3326451_0 Glycogen debranching enzyme - - - 1.52e-264 826.0
PYH2_k127_3326451_1 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 619.0
PYH2_k127_3326451_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 493.0
PYH2_k127_3326451_3 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.0000000000000000000000000000000000000001373 157.0
PYH2_k127_333840_0 His Kinase A (phosphoacceptor) domain - - - 3.408e-241 782.0
PYH2_k127_3357857_0 alpha-galactosidase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 423.0
PYH2_k127_3357857_1 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.0000000000000000000000003685 106.0
PYH2_k127_3373197_0 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 588.0
PYH2_k127_3373197_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 318.0
PYH2_k127_3373197_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000003156 215.0
PYH2_k127_3373197_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000004791 126.0
PYH2_k127_3373197_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000001684 74.0
PYH2_k127_3373197_5 Methyl-transferase - - - 0.0001684 50.0
PYH2_k127_3421343_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.304e-243 772.0
PYH2_k127_3421343_1 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 407.0
PYH2_k127_3421343_10 - - - - 0.0000005898 53.0
PYH2_k127_3421343_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 318.0
PYH2_k127_3421343_3 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000003888 207.0
PYH2_k127_3421343_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000001784 199.0
PYH2_k127_3421343_5 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000004778 201.0
PYH2_k127_3421343_6 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000003389 151.0
PYH2_k127_3421343_7 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000004554 143.0
PYH2_k127_3421343_8 serine threonine protein kinase - - - 0.0000000000000000006254 94.0
PYH2_k127_3421343_9 glyoxalase III activity - - - 0.0000002179 58.0
PYH2_k127_3473752_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 7.832e-266 833.0
PYH2_k127_352890_0 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 467.0
PYH2_k127_352890_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 394.0
PYH2_k127_352890_10 Acetyltransferase (GNAT) domain - - - 0.00002373 52.0
PYH2_k127_352890_2 PFAM ABC-1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 389.0
PYH2_k127_352890_3 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 362.0
PYH2_k127_352890_4 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 338.0
PYH2_k127_352890_5 PFAM aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 327.0
PYH2_k127_352890_6 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000004107 194.0
PYH2_k127_352890_7 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.000000000000000000000000000000001143 136.0
PYH2_k127_352890_8 Bacterial PH domain - - - 0.00000000000000000000000000001008 130.0
PYH2_k127_352890_9 Transglycosylase SLT domain - - - 0.000000000005022 76.0
PYH2_k127_3551255_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 4.735e-217 685.0
PYH2_k127_3551255_1 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 2.505e-199 629.0
PYH2_k127_3551255_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 541.0
PYH2_k127_3551255_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 531.0
PYH2_k127_3551255_4 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 423.0
PYH2_k127_3551255_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009772 243.0
PYH2_k127_3551255_6 PFAM NIF3 (NGG1p interacting factor 3) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000001696 231.0
PYH2_k127_3551255_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000002272 186.0
PYH2_k127_3558837_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 307.0
PYH2_k127_3558837_1 protein deglycation K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000008771 229.0
PYH2_k127_3558837_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000001772 217.0
PYH2_k127_3558837_3 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000003475 191.0
PYH2_k127_3558837_4 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000009183 191.0
PYH2_k127_3558837_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000001058 165.0
PYH2_k127_3558837_6 Permease K07088 - - 0.0000000000000000000000007872 115.0
PYH2_k127_3558837_7 Sterol carrier protein - - - 0.000000000000000001499 89.0
PYH2_k127_3584751_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.999e-294 923.0
PYH2_k127_3584751_1 PFAM ABC transporter related - - - 1.905e-269 838.0
PYH2_k127_3584751_10 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000446 271.0
PYH2_k127_3584751_11 oxidation-reduction process - - - 0.00000000000000000000000000000000003865 138.0
PYH2_k127_3584751_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000002156 126.0
PYH2_k127_3584751_13 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000009347 121.0
PYH2_k127_3584751_14 Belongs to the UPF0109 family K06960 - - 0.0000000000000000001528 90.0
PYH2_k127_3584751_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 7.719e-242 756.0
PYH2_k127_3584751_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 550.0
PYH2_k127_3584751_4 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 505.0
PYH2_k127_3584751_5 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 373.0
PYH2_k127_3584751_6 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 363.0
PYH2_k127_3584751_7 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 351.0
PYH2_k127_3584751_8 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 336.0
PYH2_k127_3584751_9 Xaa-Pro dipeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 306.0
PYH2_k127_3598130_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001414 254.0
PYH2_k127_3598130_1 DNA-binding transcription factor activity K15973 - - 0.0000000000000000000000000000000000000000004025 162.0
PYH2_k127_3598130_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000008985 161.0
PYH2_k127_3598130_3 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000004221 124.0
PYH2_k127_3598130_4 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000007998 123.0
PYH2_k127_3598130_5 - - - - 0.000000000000000000000001303 117.0
PYH2_k127_3598130_6 response to heat - - - 0.00000235 60.0
PYH2_k127_3745387_0 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 417.0
PYH2_k127_3745387_1 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 357.0
PYH2_k127_3745387_2 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002297 282.0
PYH2_k127_3745387_3 Natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 255.0
PYH2_k127_3745387_4 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
PYH2_k127_3745387_5 EamA-like transporter family K03298 - - 0.000000000000000000000000000000000006697 148.0
PYH2_k127_3745387_6 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.000000000000000000000000000000004777 138.0
PYH2_k127_3745387_7 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000006564 83.0
PYH2_k127_3748421_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
PYH2_k127_3748421_1 acyl-CoA dehydrogenase family, member 10 K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000004868 95.0
PYH2_k127_3748421_2 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000107 78.0
PYH2_k127_3749075_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.175e-220 695.0
PYH2_k127_3749075_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 471.0
PYH2_k127_3749075_10 - - - - 0.000003141 53.0
PYH2_k127_3749075_2 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 444.0
PYH2_k127_3749075_3 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 385.0
PYH2_k127_3749075_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 361.0
PYH2_k127_3749075_5 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 358.0
PYH2_k127_3749075_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000001514 200.0
PYH2_k127_3749075_7 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000001245 183.0
PYH2_k127_3749075_8 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000009943 113.0
PYH2_k127_3749075_9 PFAM RNA recognition motif - - - 0.0000000000000000000000001504 113.0
PYH2_k127_3750026_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 304.0
PYH2_k127_3750026_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
PYH2_k127_3750026_10 Cupin domain - - - 0.00002464 52.0
PYH2_k127_3750026_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0001724 51.0
PYH2_k127_3750026_2 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000004438 160.0
PYH2_k127_3750026_3 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000006883 144.0
PYH2_k127_3750026_4 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000006038 147.0
PYH2_k127_3750026_5 Cytochrome c - - - 0.0000000000000000000000000000000002884 151.0
PYH2_k127_3750026_6 PFAM Cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000758 138.0
PYH2_k127_3750026_7 MarR family transcriptional regulator - - - 0.000000000000000003257 85.0
PYH2_k127_3750026_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000336 77.0
PYH2_k127_3750026_9 Hemerythrin HHE cation binding domain - - - 0.0000008372 56.0
PYH2_k127_3753075_0 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 294.0
PYH2_k127_3753075_1 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000007122 94.0
PYH2_k127_3753737_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 391.0
PYH2_k127_3753737_1 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000006262 223.0
PYH2_k127_3753737_2 Secreted repeat of unknown function - - - 0.00000000000000000000000000000002241 128.0
PYH2_k127_3753737_3 extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000001045 131.0
PYH2_k127_3753737_4 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000001275 94.0
PYH2_k127_3753737_5 membrane - - - 0.000000000000002559 85.0
PYH2_k127_376498_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 603.0
PYH2_k127_376498_1 cell wall glycoprotein biosynthetic process K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 413.0
PYH2_k127_376498_10 3-hexulose-6-phosphate synthase K08093 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 0.000000000000000000000000000000000000000007773 162.0
PYH2_k127_376498_11 6-phospho 3-hexuloisomerase K08094 - 5.3.1.27 0.00000000000000000000000000000000000001352 151.0
PYH2_k127_376498_12 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000007267 153.0
PYH2_k127_376498_13 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.00000000000000000000000000000007747 135.0
PYH2_k127_376498_14 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000000000001798 117.0
PYH2_k127_376498_15 PTS system sorbose subfamily IIB component - - - 0.000000000000000000000000001068 118.0
PYH2_k127_376498_16 IIa component K02793 - 2.7.1.191 0.00000000000000000000000153 108.0
PYH2_k127_376498_17 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000003213 98.0
PYH2_k127_376498_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 353.0
PYH2_k127_376498_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 295.0
PYH2_k127_376498_4 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000003699 260.0
PYH2_k127_376498_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000914 249.0
PYH2_k127_376498_6 PTS system mannose/fructose/sorbose family IID component K02771 - - 0.0000000000000000000000000000000000000000000000000001561 193.0
PYH2_k127_376498_7 SIS domain - - - 0.0000000000000000000000000000000000000000000000000006652 192.0
PYH2_k127_376498_8 protein containing SIS (Sugar ISomerase) phosphosugar binding domain - - - 0.000000000000000000000000000000000000000000000000609 184.0
PYH2_k127_376498_9 glucose-6-phosphate isomerase K06859 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.0000000000000000000000000000000000000000004467 165.0
PYH2_k127_3775131_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.021e-202 638.0
PYH2_k127_3775131_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 387.0
PYH2_k127_3775131_2 - - - - 0.0000000000000000000000000000000005625 136.0
PYH2_k127_3775131_3 F420H(2)-dependent quinone reductase - - - 0.000002841 56.0
PYH2_k127_3775131_4 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000368 49.0
PYH2_k127_3781349_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000003722 199.0
PYH2_k127_3781349_1 serine threonine protein kinase - - - 0.00000003169 63.0
PYH2_k127_3808583_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 364.0
PYH2_k127_3808583_1 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000008329 176.0
PYH2_k127_3808583_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000166 108.0
PYH2_k127_3822391_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 566.0
PYH2_k127_3822391_1 FMN binding - - - 0.00000000000000000000000000000000000003082 145.0
PYH2_k127_3828964_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 531.0
PYH2_k127_3828964_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 295.0
PYH2_k127_3828964_10 Serine aminopeptidase, S33 - - - 0.000000002441 58.0
PYH2_k127_3828964_11 PFAM Tetratricopeptide repeat - - - 0.000005982 59.0
PYH2_k127_3828964_13 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0001089 49.0
PYH2_k127_3828964_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008675 267.0
PYH2_k127_3828964_3 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000009382 238.0
PYH2_k127_3828964_4 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000001349 228.0
PYH2_k127_3828964_5 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000002751 216.0
PYH2_k127_3828964_6 GrpB protein - - - 0.0000000000000000000000000000000000000000002459 164.0
PYH2_k127_3828964_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000128 153.0
PYH2_k127_3828964_8 Alpha beta hydrolase - - - 0.000000000000005914 78.0
PYH2_k127_3830_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 4.894e-224 706.0
PYH2_k127_3830_1 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 316.0
PYH2_k127_3841310_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
PYH2_k127_3841310_1 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002385 256.0
PYH2_k127_3841310_2 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000002412 173.0
PYH2_k127_3841310_3 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.000000000000000000000001108 104.0
PYH2_k127_3841310_4 pyridoxamine 5'-phosphate K07005 - - 0.00000006349 57.0
PYH2_k127_3844829_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 574.0
PYH2_k127_3844829_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876,K09759 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001919 237.0
PYH2_k127_3844829_2 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000004207 186.0
PYH2_k127_3846157_0 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001108 285.0
PYH2_k127_3846157_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000003118 229.0
PYH2_k127_3846157_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000005808 175.0
PYH2_k127_3846819_0 short-chain dehydrogenase reductase SDR - - - 7.801e-212 676.0
PYH2_k127_3846819_1 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 313.0
PYH2_k127_3846819_2 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000003346 154.0
PYH2_k127_3846819_3 -O-antigen K13009,K18814 - - 0.000000000000000000000000000001534 136.0
PYH2_k127_3846819_4 Bacterial SH3 domain - - - 0.00003818 53.0
PYH2_k127_3847298_0 ABC transporter K02056 - 3.6.3.17 6.262e-200 634.0
PYH2_k127_3847298_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 509.0
PYH2_k127_3847298_2 PFAM amidohydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 493.0
PYH2_k127_3847298_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 477.0
PYH2_k127_3847298_4 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 371.0
PYH2_k127_3847298_5 Ftsk_gamma K03466 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 354.0
PYH2_k127_3847298_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000004642 87.0
PYH2_k127_3847298_7 PFAM CBS domain containing protein - - - 0.000000000000342 71.0
PYH2_k127_3849091_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 3.315e-203 645.0
PYH2_k127_3849661_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 346.0
PYH2_k127_3849661_1 ATPase family associated with various cellular activities (AAA) K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 357.0
PYH2_k127_3878968_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 552.0
PYH2_k127_3878968_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 442.0
PYH2_k127_3878968_2 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000004224 124.0
PYH2_k127_3878968_4 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.00001565 51.0
PYH2_k127_3896931_0 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 439.0
PYH2_k127_3896931_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001401 275.0
PYH2_k127_3896931_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000006061 100.0
PYH2_k127_3896931_3 belongs to the thioredoxin family - - - 0.00000000794 67.0
PYH2_k127_3896931_4 PFAM blue (type 1) copper domain protein - - - 0.0006291 42.0
PYH2_k127_3903467_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 531.0
PYH2_k127_3903467_1 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 490.0
PYH2_k127_3903467_10 - - - - 0.00004346 52.0
PYH2_k127_3903467_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 380.0
PYH2_k127_3903467_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 325.0
PYH2_k127_3903467_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 298.0
PYH2_k127_3903467_5 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001852 251.0
PYH2_k127_3903467_6 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000009154 233.0
PYH2_k127_3903467_7 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000005266 186.0
PYH2_k127_3903467_8 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000002067 160.0
PYH2_k127_3903467_9 belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25,6.3.2.1 0.00000000000000000000008948 102.0
PYH2_k127_3919793_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.026e-229 734.0
PYH2_k127_3919793_1 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.00000000000000000000000000000000000000000000000000000000000194 229.0
PYH2_k127_3919793_2 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000001203 198.0
PYH2_k127_3929810_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 332.0
PYH2_k127_3929810_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003276 268.0
PYH2_k127_3929810_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009501 267.0
PYH2_k127_3929810_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 258.0
PYH2_k127_3929810_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000008993 195.0
PYH2_k127_3929810_5 GtrA-like protein - - - 0.0000000000000048 78.0
PYH2_k127_3929810_6 COG NOG22472 non supervised orthologous group - - - 0.000003608 60.0
PYH2_k127_3933793_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 3.581e-214 677.0
PYH2_k127_3933793_1 Glycoside hydrolase family 44 - - - 6.463e-194 629.0
PYH2_k127_3933793_10 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000004946 239.0
PYH2_k127_3933793_11 photosynthesis - - - 0.0000000000000000000000000000000000000000000006197 171.0
PYH2_k127_3933793_12 The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000005811 164.0
PYH2_k127_3933793_13 acetyltransferase - - - 0.000000000000000000000000000000000003105 151.0
PYH2_k127_3933793_14 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000005129 131.0
PYH2_k127_3933793_15 PFAM Nitroreductase - - - 0.00000000000000000000000000007104 122.0
PYH2_k127_3933793_16 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000006029 115.0
PYH2_k127_3933793_17 alpha-L-arabinofuranosidase - - - 0.00000000000000000000001694 117.0
PYH2_k127_3933793_18 Arrestin domain-containing protein - - - 0.00000000005174 73.0
PYH2_k127_3933793_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 544.0
PYH2_k127_3933793_3 3-isopropylmalate dehydrogenase activity K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 527.0
PYH2_k127_3933793_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 458.0
PYH2_k127_3933793_5 S-(hydroxymethyl)glutathione dehydrogenase activity K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 440.0
PYH2_k127_3933793_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 391.0
PYH2_k127_3933793_7 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006971 280.0
PYH2_k127_3933793_8 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003059 279.0
PYH2_k127_3933793_9 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008264 274.0
PYH2_k127_3935895_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 488.0
PYH2_k127_3935895_1 formate dehydrogenase (NAD+) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002717 230.0
PYH2_k127_3935895_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000001904 226.0
PYH2_k127_3935895_3 diguanylate cyclase - - - 0.000000000000000000000000003123 121.0
PYH2_k127_3937937_0 Belongs to the DegT DnrJ EryC1 family K16436 - 2.6.1.106 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 423.0
PYH2_k127_3937937_1 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 362.0
PYH2_k127_3937937_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 320.0
PYH2_k127_3937937_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000974 146.0
PYH2_k127_3937937_4 - - - - 0.00000000000000000000000000000001274 134.0
PYH2_k127_3949394_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 466.0
PYH2_k127_3949394_1 RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
PYH2_k127_3949394_2 NACHT domain K13730 - - 0.000000000000000000000000000006548 123.0
PYH2_k127_3949394_3 amine dehydrogenase activity - - - 0.000003131 60.0
PYH2_k127_3949394_4 - - - - 0.0005876 47.0
PYH2_k127_3950368_0 Thioredoxin - - - 0.00000000000000000000000000000000000000000000006813 177.0
PYH2_k127_3950368_1 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000003759 164.0
PYH2_k127_3950368_2 VIT family - - - 0.000000000000000000000000000002059 130.0
PYH2_k127_3950368_3 quinone binding - - - 0.00000000000000000003706 96.0
PYH2_k127_3970638_0 PFAM ABC transporter related K06147 - - 5.78e-197 625.0
PYH2_k127_3970638_1 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.000000000000000000000000000000008573 138.0
PYH2_k127_3970638_2 DinB family - - - 0.00000000000000000000000002789 114.0
PYH2_k127_3972992_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 5.621e-226 707.0
PYH2_k127_3972992_1 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006759 262.0
PYH2_k127_3972992_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000001403 199.0
PYH2_k127_3972992_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000003129 180.0
PYH2_k127_3972992_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000001149 156.0
PYH2_k127_3972992_5 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000005393 122.0
PYH2_k127_3972992_6 MazG-like family - - - 0.00000000000000000000000005438 111.0
PYH2_k127_3975051_0 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 353.0
PYH2_k127_3975051_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 342.0
PYH2_k127_3975051_2 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000003213 173.0
PYH2_k127_3975051_3 - - - - 0.0000000000000000000000002617 112.0
PYH2_k127_3975051_4 zinc-ribbon domain - - - 0.0000000000000003492 83.0
PYH2_k127_3975051_5 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000001409 65.0
PYH2_k127_3975051_6 zinc-ribbon domain - - - 0.00005188 48.0
PYH2_k127_3992612_0 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000000000000000000000000000002044 194.0
PYH2_k127_3992612_1 Thioredoxin - - - 0.000000000000000000000000000000000002137 149.0
PYH2_k127_3992612_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000008952 98.0
PYH2_k127_3992612_3 Conserved Protein - - - 0.00000000000000000005144 93.0
PYH2_k127_3992612_4 pfam yhs - - - 0.00000000000009333 74.0
PYH2_k127_400417_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 544.0
PYH2_k127_400417_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 520.0
PYH2_k127_400417_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 408.0
PYH2_k127_400417_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000007531 183.0
PYH2_k127_4062064_0 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006037 275.0
PYH2_k127_4062064_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000231 138.0
PYH2_k127_4062064_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000007076 113.0
PYH2_k127_4062064_3 - - - - 0.00000000000000000004804 96.0
PYH2_k127_4062064_4 - - - - 0.00000001569 56.0
PYH2_k127_4130542_0 response regulator - - - 0.0000000000000000000000000000000000000000000000009673 180.0
PYH2_k127_4130542_1 Histidine kinase - - - 0.00000000000000000000000000000000000000007664 167.0
PYH2_k127_4134839_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000909 237.0
PYH2_k127_4134839_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000009376 214.0
PYH2_k127_4134839_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000003563 214.0
PYH2_k127_4139641_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 539.0
PYH2_k127_4139641_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000004123 156.0
PYH2_k127_4161904_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 5.916e-222 696.0
PYH2_k127_4161904_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.929e-202 636.0
PYH2_k127_4161904_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000005078 86.0
PYH2_k127_4161904_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 524.0
PYH2_k127_4161904_3 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 333.0
PYH2_k127_4161904_4 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 288.0
PYH2_k127_4161904_5 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 283.0
PYH2_k127_4161904_6 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000002705 250.0
PYH2_k127_4161904_7 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008544 254.0
PYH2_k127_4161904_8 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000005802 128.0
PYH2_k127_4161904_9 FR47-like protein - - - 0.0000000000000000000000008896 114.0
PYH2_k127_4165684_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 400.0
PYH2_k127_4165684_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000006021 158.0
PYH2_k127_4165684_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000004595 139.0
PYH2_k127_4165684_3 Helix-turn-helix domain - - - 0.00000000000000000003428 102.0
PYH2_k127_4172271_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 461.0
PYH2_k127_4172271_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 316.0
PYH2_k127_4172271_2 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000198 167.0
PYH2_k127_4172271_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000689 112.0
PYH2_k127_418549_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 506.0
PYH2_k127_418549_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000001573 138.0
PYH2_k127_418549_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000005685 135.0
PYH2_k127_418549_3 PFAM secretion protein HlyD family protein K02005 - - 0.00000000000000000000001105 114.0
PYH2_k127_4188508_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 370.0
PYH2_k127_4188508_1 Vitamin k epoxide reductase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001746 286.0
PYH2_k127_4188508_10 Auxin binding protein - - - 0.0000000001452 67.0
PYH2_k127_4188508_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000004221 73.0
PYH2_k127_4188508_2 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003883 280.0
PYH2_k127_4188508_3 - - - - 0.0000000000000000000000000000000000005207 144.0
PYH2_k127_4188508_4 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000003301 146.0
PYH2_k127_4188508_5 - - - - 0.00000000000000000000000000000000004817 138.0
PYH2_k127_4188508_6 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000008642 142.0
PYH2_k127_4188508_7 integral membrane protein - - - 0.00000000000000000000000003717 114.0
PYH2_k127_4188508_8 Domain of unknown function (DUF4342) - - - 0.00000000000000000005997 92.0
PYH2_k127_4188508_9 YwiC-like protein - - - 0.000000000000002461 86.0
PYH2_k127_420537_0 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
PYH2_k127_420537_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 336.0
PYH2_k127_420537_2 diacylglycerol kinase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000003648 238.0
PYH2_k127_420537_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000003615 225.0
PYH2_k127_420537_4 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000521 59.0
PYH2_k127_4234419_0 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000004367 187.0
PYH2_k127_4234419_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000001036 123.0
PYH2_k127_4234419_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000006346 79.0
PYH2_k127_4235661_0 Aldehyde ferredoxin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 338.0
PYH2_k127_4235661_1 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000002817 64.0
PYH2_k127_4243315_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 572.0
PYH2_k127_4243315_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 572.0
PYH2_k127_4243315_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000002878 190.0
PYH2_k127_4243315_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001467 171.0
PYH2_k127_4243315_12 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000002287 149.0
PYH2_k127_4243315_13 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000008191 142.0
PYH2_k127_4243315_14 HNH endonuclease K07451 - - 0.000000000000000000000000000001402 126.0
PYH2_k127_4243315_15 - - - - 0.000000000000000000000000000001418 125.0
PYH2_k127_4243315_16 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000008109 117.0
PYH2_k127_4243315_17 - - - - 0.000000000000000000000001723 116.0
PYH2_k127_4243315_18 PFAM membrane protein of K08972 - - 0.00000000000000000000002916 104.0
PYH2_k127_4243315_19 - - - - 0.000000000000000000211 92.0
PYH2_k127_4243315_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 496.0
PYH2_k127_4243315_20 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000005974 93.0
PYH2_k127_4243315_21 Domain of unknown function (DUF4286) - - - 0.000000000000004121 82.0
PYH2_k127_4243315_22 Acetyltransferase (GNAT) family - - - 0.00000000000005711 84.0
PYH2_k127_4243315_23 UbiA prenyltransferase family K20616 - - 0.00000000000006745 82.0
PYH2_k127_4243315_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000001409 63.0
PYH2_k127_4243315_27 Acetyltransferase (GNAT) domain - - - 0.0000001071 64.0
PYH2_k127_4243315_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 466.0
PYH2_k127_4243315_4 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 447.0
PYH2_k127_4243315_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 391.0
PYH2_k127_4243315_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 381.0
PYH2_k127_4243315_7 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
PYH2_k127_4243315_8 Polysaccharide biosynthesis protein K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 318.0
PYH2_k127_4243315_9 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000003138 211.0
PYH2_k127_427734_0 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000000000001341 136.0
PYH2_k127_43572_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.337e-218 696.0
PYH2_k127_43572_1 Predicted membrane protein (DUF2177) - - - 0.0002065 44.0
PYH2_k127_4393203_0 NAD(P)H-binding K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000003061 196.0
PYH2_k127_4393203_1 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000001741 158.0
PYH2_k127_4393203_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K02548,K03179,K17105 - 2.5.1.39,2.5.1.42,2.5.1.74 0.0000000000000000000000000000005998 133.0
PYH2_k127_440981_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 344.0
PYH2_k127_440981_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000002981 132.0
PYH2_k127_440981_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000002442 107.0
PYH2_k127_440981_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000001569 89.0
PYH2_k127_440981_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000725 58.0
PYH2_k127_4419822_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000004621 223.0
PYH2_k127_4419822_1 DinB superfamily - - - 0.000000000000000000000000000000000000000008184 159.0
PYH2_k127_4456677_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 422.0
PYH2_k127_448121_0 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 466.0
PYH2_k127_448121_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 374.0
PYH2_k127_448121_2 endonuclease exonuclease phosphatase K07004 - - 0.0000000000000001775 93.0
PYH2_k127_448121_3 HWE histidine kinase - - - 0.000000002187 64.0
PYH2_k127_4603393_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000007121 62.0
PYH2_k127_462603_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 362.0
PYH2_k127_462603_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003383 277.0
PYH2_k127_462603_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001212 260.0
PYH2_k127_462603_3 2-phosphoglycerate kinase K05715 - - 0.000007813 55.0
PYH2_k127_466852_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 278.0
PYH2_k127_466852_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000006018 169.0
PYH2_k127_466852_2 Pfam:DUF2029 - - - 0.00000000000000000000000001933 122.0
PYH2_k127_4677626_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 6.15e-264 843.0
PYH2_k127_4677626_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 402.0
PYH2_k127_4677626_2 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000001227 132.0
PYH2_k127_4677626_3 SMART Tetratricopeptide repeat - - - 0.0000000000001769 76.0
PYH2_k127_4703912_0 PFAM Glycosyl transferase family 2 K14597 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001306 286.0
PYH2_k127_4703912_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000379 188.0
PYH2_k127_4703912_2 Serine hydrolase (FSH1) K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000943 181.0
PYH2_k127_4708809_0 response regulator K07668,K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000000009339 239.0
PYH2_k127_4708809_1 EDD domain protein, DegV family - - - 0.00000000000000000000000000000000000000000000000000000000000000002897 233.0
PYH2_k127_4708809_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000006392 167.0
PYH2_k127_4708809_3 Phospholipase K06999 - - 0.000000000000000000000000000001023 132.0
PYH2_k127_4708809_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000005155 66.0
PYH2_k127_4709636_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 6.735e-304 947.0
PYH2_k127_4709636_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 554.0
PYH2_k127_4709636_2 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 405.0
PYH2_k127_4709636_3 Putative esterase - - - 0.0000008862 55.0
PYH2_k127_4710392_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 314.0
PYH2_k127_4710392_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000004344 256.0
PYH2_k127_4710392_2 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000001932 228.0
PYH2_k127_4710392_3 - - - - 0.00000000000000000000000000000000000000001182 167.0
PYH2_k127_4710392_4 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000006776 130.0
PYH2_k127_4710392_5 Bacterial membrane protein YfhO - - - 0.00000000004645 68.0
PYH2_k127_4711987_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001199 194.0
PYH2_k127_4712257_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 613.0
PYH2_k127_4712257_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 518.0
PYH2_k127_4712257_2 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000008106 213.0
PYH2_k127_4712257_3 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000001407 162.0
PYH2_k127_4712257_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000009489 150.0
PYH2_k127_4712257_5 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000007145 106.0
PYH2_k127_4716624_0 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 1.191e-269 868.0
PYH2_k127_4716624_1 Anion-transporting ATPase K01551 - 3.6.3.16 3.059e-200 642.0
PYH2_k127_4716624_10 Control of competence regulator ComK, YlbF/YmcA - - - 0.000001383 55.0
PYH2_k127_4716624_2 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 596.0
PYH2_k127_4716624_3 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 472.0
PYH2_k127_4716624_4 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000002211 177.0
PYH2_k127_4716624_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000003183 151.0
PYH2_k127_4716624_6 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000003525 108.0
PYH2_k127_4716624_7 Iron-sulfur cluster assembly protein - - - 0.00000000132 63.0
PYH2_k127_4716624_9 Control of competence regulator ComK, YlbF/YmcA - - - 0.000000007863 62.0
PYH2_k127_4718965_0 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003828 278.0
PYH2_k127_4718965_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002058 271.0
PYH2_k127_4718965_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000004141 221.0
PYH2_k127_4718965_3 Transcriptional regulatory protein, C terminal K02483,K07667 GO:0008150,GO:0040007 - 0.000000000000000000000000008788 112.0
PYH2_k127_4718965_4 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000001924 70.0
PYH2_k127_4722539_0 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 426.0
PYH2_k127_4722539_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004155 282.0
PYH2_k127_4722539_2 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000003962 228.0
PYH2_k127_4722539_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000406 137.0
PYH2_k127_4722539_4 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000001716 110.0
PYH2_k127_4747395_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 450.0
PYH2_k127_4747395_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 245.0
PYH2_k127_4747395_2 - - - - 0.000000000000000001001 94.0
PYH2_k127_4747395_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00004567 47.0
PYH2_k127_4749256_0 Belongs to the peptidase S16 family - - - 2.212e-205 666.0
PYH2_k127_4749256_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 409.0
PYH2_k127_4749256_10 DNA Methylase - - - 0.00006113 56.0
PYH2_k127_4749256_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007104 259.0
PYH2_k127_4749256_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000004334 225.0
PYH2_k127_4749256_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000001245 198.0
PYH2_k127_4749256_5 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000179 162.0
PYH2_k127_4749256_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000004986 153.0
PYH2_k127_4749256_7 PspC domain - - - 0.000000000000000000000000004941 116.0
PYH2_k127_4749256_8 LysM domain K12204 - - 0.00000000000000000000006787 112.0
PYH2_k127_4749256_9 Helix-turn-helix - - - 0.00000000000000000001282 93.0
PYH2_k127_4751595_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 580.0
PYH2_k127_4751595_1 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 345.0
PYH2_k127_4751595_2 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 297.0
PYH2_k127_4751595_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000004962 206.0
PYH2_k127_4751595_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000001814 156.0
PYH2_k127_4751595_5 Asp23 family, cell envelope-related function - - - 0.00000000000000001761 85.0
PYH2_k127_4751595_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000008454 53.0
PYH2_k127_477494_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 441.0
PYH2_k127_477494_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000001728 236.0
PYH2_k127_477494_2 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000584 160.0
PYH2_k127_477494_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000001506 105.0
PYH2_k127_477494_4 Belongs to the Nudix hydrolase family - - - 0.00000000000002041 79.0
PYH2_k127_4781973_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
PYH2_k127_4781973_1 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003157 282.0
PYH2_k127_4781973_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009723 268.0
PYH2_k127_4781973_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000008034 181.0
PYH2_k127_4781973_4 - - - - 0.0000000000000009615 83.0
PYH2_k127_4797513_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 399.0
PYH2_k127_4797513_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 295.0
PYH2_k127_4797513_2 Membrane - - - 0.0000000000000000000002327 108.0
PYH2_k127_4797513_3 Belongs to the UPF0306 family K09979 - - 0.0000000000000000003791 93.0
PYH2_k127_4797513_4 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000003474 55.0
PYH2_k127_4820258_0 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 305.0
PYH2_k127_4820258_1 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000001117 250.0
PYH2_k127_4820258_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000003688 176.0
PYH2_k127_4820258_3 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000001057 145.0
PYH2_k127_4820258_4 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000001513 106.0
PYH2_k127_482612_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001116 277.0
PYH2_k127_482612_1 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003565 273.0
PYH2_k127_482612_2 lysyltransferase activity K07027 - - 0.00000000000000005675 95.0
PYH2_k127_483536_0 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 296.0
PYH2_k127_483536_1 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000003945 232.0
PYH2_k127_483536_2 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000002802 235.0
PYH2_k127_483536_3 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000005958 181.0
PYH2_k127_483536_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000008672 169.0
PYH2_k127_483536_5 competence protein - - - 0.000000000000000000000000000000000000000003127 164.0
PYH2_k127_4842220_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.837e-210 679.0
PYH2_k127_4842220_1 PFAM Dak phosphatase K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 469.0
PYH2_k127_4842220_10 ubiE/COQ5 methyltransferase family - - - 0.0000000001709 61.0
PYH2_k127_4842220_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
PYH2_k127_4842220_3 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000002168 224.0
PYH2_k127_4842220_4 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000006915 216.0
PYH2_k127_4842220_5 alpha, beta K06889 - - 0.000000000000000000000000000000000001602 147.0
PYH2_k127_4842220_6 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000004534 135.0
PYH2_k127_4842220_7 Asp23 family, cell envelope-related function - - - 0.0000000000000000000001643 100.0
PYH2_k127_4842220_8 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000002508 100.0
PYH2_k127_4842220_9 Ribosomal L28 family K02902 - - 0.0000000000000003262 81.0
PYH2_k127_4853883_0 PFAM deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 286.0
PYH2_k127_4853883_1 DUF218 domain - - - 0.0000000000000000000000000000002564 128.0
PYH2_k127_4853883_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000924 106.0
PYH2_k127_4858953_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.414e-280 876.0
PYH2_k127_4858953_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 530.0
PYH2_k127_4858953_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 449.0
PYH2_k127_4858953_3 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 398.0
PYH2_k127_4858953_4 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 356.0
PYH2_k127_4858953_5 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000001525 222.0
PYH2_k127_4858953_6 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000000000000000000000006208 201.0
PYH2_k127_4858953_7 Protein of unknown function (DUF4230) - - - 0.000000000000000001127 94.0
PYH2_k127_4858953_8 TIGRFAM molybdenum cofactor synthesis domain - - - 0.000000000000000005424 84.0
PYH2_k127_4858953_9 PhoQ Sensor - - - 0.00000519 49.0
PYH2_k127_4869623_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 8.26e-204 648.0
PYH2_k127_4869623_1 serine-type peptidase activity - - - 0.000000000000000000000000000004064 122.0
PYH2_k127_4872647_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 418.0
PYH2_k127_4872647_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 306.0
PYH2_k127_4872647_2 amidohydrolase - - - 0.0000000000000000000000000000000000000004198 158.0
PYH2_k127_4872858_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.455e-256 810.0
PYH2_k127_4872858_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 334.0
PYH2_k127_4872858_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000005626 183.0
PYH2_k127_4874274_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000008263 198.0
PYH2_k127_4874274_1 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000001826 140.0
PYH2_k127_4890048_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 595.0
PYH2_k127_4890048_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 548.0
PYH2_k127_4890048_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000001051 115.0
PYH2_k127_4890048_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000002674 72.0
PYH2_k127_4890048_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0002274 44.0
PYH2_k127_4890171_0 Required for chromosome condensation and partitioning K03529 - - 6.39e-223 734.0
PYH2_k127_4890171_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005415 267.0
PYH2_k127_4890171_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000002984 223.0
PYH2_k127_4890171_3 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000000000001901 178.0
PYH2_k127_4890171_4 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000001169 171.0
PYH2_k127_4890171_5 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000006977 73.0
PYH2_k127_4890171_6 succinate dehydrogenase K00241 - - 0.00000003705 60.0
PYH2_k127_4890171_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000002271 54.0
PYH2_k127_4894368_0 ABC transporter K10441 - 3.6.3.17 1.681e-199 636.0
PYH2_k127_4894368_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 535.0
PYH2_k127_4894368_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 465.0
PYH2_k127_4894368_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 431.0
PYH2_k127_4894368_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 417.0
PYH2_k127_4894368_5 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 404.0
PYH2_k127_4894368_6 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 302.0
PYH2_k127_4894368_7 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008702 261.0
PYH2_k127_4894368_8 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000882 162.0
PYH2_k127_4894956_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 388.0
PYH2_k127_4894956_1 PFAM peptidase, membrane zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
PYH2_k127_4894956_2 Receptor family ligand binding region K01999,K11954 - - 0.0000000004533 64.0
PYH2_k127_4911474_0 L-aspartate oxidase K00278 - 1.4.3.16 7.463e-235 736.0
PYH2_k127_4911474_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 546.0
PYH2_k127_4911474_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 333.0
PYH2_k127_4911474_3 XRE family transcriptional regulator K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000002956 212.0
PYH2_k127_4911474_4 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000466 120.0
PYH2_k127_4916544_0 PFAM O-antigen polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 355.0
PYH2_k127_4916544_1 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000000000009515 118.0
PYH2_k127_4916544_2 STAS domain K04749 - - 0.000000000000002318 80.0
PYH2_k127_4923336_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 495.0
PYH2_k127_4923336_1 - - - - 0.000000000000000000000000000000000000000000000000000000006664 214.0
PYH2_k127_4923336_2 integral membrane protein - - - 0.0000000000000000000000000000000004571 149.0
PYH2_k127_4923336_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000001758 123.0
PYH2_k127_4923336_4 - - - - 0.0000000000000000005031 94.0
PYH2_k127_4923336_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002532 48.0
PYH2_k127_4927860_0 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 1.513e-197 630.0
PYH2_k127_494816_0 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 311.0
PYH2_k127_494816_1 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000001543 217.0
PYH2_k127_4988038_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 6.585e-239 747.0
PYH2_k127_4988038_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 535.0
PYH2_k127_4988038_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 455.0
PYH2_k127_4988038_3 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 419.0
PYH2_k127_4988038_4 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 346.0
PYH2_k127_4988038_5 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000002322 182.0
PYH2_k127_4988038_6 PFAM nitrogen-fixing NifU domain protein K04488 - - 0.00000000000000000000000000000000000009586 145.0
PYH2_k127_4988038_7 of nitrite reductase and ring-hydroxylating K05710 - - 0.000000000000000000000005605 104.0
PYH2_k127_4988038_8 Inositol monophosphatase K01092 - 3.1.3.25 0.000000004797 58.0
PYH2_k127_4994389_0 nitrite transmembrane transporter activity K02532 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 578.0
PYH2_k127_4994389_1 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
PYH2_k127_4994389_2 superoxide dismutase activity K02674,K04565 - 1.15.1.1 0.0000000000007601 79.0
PYH2_k127_4997032_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000004086 141.0
PYH2_k127_4997032_1 glycosyl transferase, family 39 - - - 0.0000000000000000000000000002575 133.0
PYH2_k127_4997032_2 PFAM glycosyl transferase family 39 - - - 0.0000001632 64.0
PYH2_k127_5010920_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 485.0
PYH2_k127_5010920_1 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
PYH2_k127_5010920_2 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
PYH2_k127_5010920_3 Low molecular weight phosphatase family - - - 0.000000000000000197 86.0
PYH2_k127_5016490_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 1.904e-267 853.0
PYH2_k127_5016490_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.245e-248 774.0
PYH2_k127_5016490_10 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000001607 151.0
PYH2_k127_5016490_11 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000323 130.0
PYH2_k127_5016490_12 bacterial-type flagellum-dependent cell motility K16147 - 2.4.99.16 0.0000000000000000000000005564 121.0
PYH2_k127_5016490_13 PFAM glycoside hydrolase family 13 domain protein - - - 0.000000000000000000000008473 103.0
PYH2_k127_5016490_14 serine-type aminopeptidase activity K02030,K14475 - - 0.00000000000000000000006372 102.0
PYH2_k127_5016490_15 Protein of unknown function (DUF2723) - - - 0.000000000000000001388 101.0
PYH2_k127_5016490_16 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000003357 87.0
PYH2_k127_5016490_17 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000003575 83.0
PYH2_k127_5016490_18 exo-alpha-(2->6)-sialidase activity - - - 0.00000000005731 75.0
PYH2_k127_5016490_19 - - - - 0.0000000665 62.0
PYH2_k127_5016490_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 526.0
PYH2_k127_5016490_20 response regulator - - - 0.0000009244 56.0
PYH2_k127_5016490_3 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 424.0
PYH2_k127_5016490_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001288 243.0
PYH2_k127_5016490_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
PYH2_k127_5016490_6 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000002454 221.0
PYH2_k127_5016490_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000006471 225.0
PYH2_k127_5016490_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000539 216.0
PYH2_k127_5016490_9 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000000004513 177.0
PYH2_k127_50548_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 512.0
PYH2_k127_50548_1 transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 325.0
PYH2_k127_50548_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000002142 233.0
PYH2_k127_50548_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000006164 216.0
PYH2_k127_50548_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000946 216.0
PYH2_k127_50548_5 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000007078 198.0
PYH2_k127_50548_6 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000001553 182.0
PYH2_k127_50548_7 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000003871 128.0
PYH2_k127_5065445_0 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000001195 203.0
PYH2_k127_5065445_1 sh3 domain protein K01227,K03642 - 3.2.1.96 0.0000000000000002449 86.0
PYH2_k127_5065445_2 photosynthesis K02656 - - 0.00000002201 66.0
PYH2_k127_5065445_3 COG3103 SH3 domain protein K01448 - 3.5.1.28 0.0002748 54.0
PYH2_k127_507676_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 494.0
PYH2_k127_507676_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000003069 233.0
PYH2_k127_507676_2 YqeY-like protein K09117 - - 0.00000000000000000000000000052 118.0
PYH2_k127_507676_3 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000659 67.0
PYH2_k127_507676_4 rab-related GTPase K07910 - - 0.0000001131 57.0
PYH2_k127_5084927_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1039.0
PYH2_k127_5084927_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 536.0
PYH2_k127_5084927_2 - - - - 0.000000000000000000000000349 121.0
PYH2_k127_5084927_3 PFAM AAA-4 family protein K02444,K03655 - 3.6.4.12 0.000000000000001244 80.0
PYH2_k127_5084927_4 Protein of unknown function (DUF2723) - - - 0.00000000000001247 88.0
PYH2_k127_51277_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 534.0
PYH2_k127_51277_1 rRNA methyltransferase activity K03500,K11392 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 372.0
PYH2_k127_51277_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 338.0
PYH2_k127_51277_3 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000009193 228.0
PYH2_k127_514215_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 504.0
PYH2_k127_514215_1 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
PYH2_k127_514215_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000006261 250.0
PYH2_k127_514215_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001103 234.0
PYH2_k127_514215_4 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.00000000000000000000000000000000001782 141.0
PYH2_k127_514215_5 TIGRFAM proline-specific peptidases, Bacillus coagulans-type subfamily K01259 - 3.4.11.5 0.0000000000000000000000000000000006554 141.0
PYH2_k127_514215_6 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000001344 124.0
PYH2_k127_5144316_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000006222 175.0
PYH2_k127_5144316_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000001151 108.0
PYH2_k127_5144316_2 AMP binding - - - 0.0000000000000000000001286 103.0
PYH2_k127_5144316_3 pfkB family carbohydrate kinase - - - 0.000000006578 69.0
PYH2_k127_5199695_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 379.0
PYH2_k127_5199695_1 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000002375 268.0
PYH2_k127_5199695_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000006429 190.0
PYH2_k127_5199695_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000001718 189.0
PYH2_k127_5199695_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000004113 177.0
PYH2_k127_5199695_5 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000001372 157.0
PYH2_k127_5199695_6 Major facilitator Superfamily - - - 0.00000000000000000000000000007008 130.0
PYH2_k127_5199695_7 phosphatase activity K07025,K20866 - 3.1.3.10 0.0000000000000000000000004377 114.0
PYH2_k127_5215580_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 591.0
PYH2_k127_5215580_1 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 574.0
PYH2_k127_5215580_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
PYH2_k127_5215580_3 NADH dehydrogenase K12138 - - 0.0000000000000000000000000000000000000000000000000000000000000008029 224.0
PYH2_k127_5215580_4 Nickel-dependent hydrogenase K15830 - - 0.0000000000000002073 80.0
PYH2_k127_5224171_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 442.0
PYH2_k127_5224171_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000004078 172.0
PYH2_k127_5224171_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000001256 55.0
PYH2_k127_530068_0 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 555.0
PYH2_k127_530068_1 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000001307 248.0
PYH2_k127_530068_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
PYH2_k127_530068_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000007125 218.0
PYH2_k127_530068_4 ResB-like family K07399 - - 0.000000000003897 79.0
PYH2_k127_5516782_0 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 528.0
PYH2_k127_5516782_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 432.0
PYH2_k127_5516782_10 - - - - 0.0000000001709 61.0
PYH2_k127_5516782_11 - - - - 0.0000000006732 61.0
PYH2_k127_5516782_12 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00001653 53.0
PYH2_k127_5516782_2 Bacterial extracellular solute-binding protein K02064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 386.0
PYH2_k127_5516782_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001724 275.0
PYH2_k127_5516782_4 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000001166 179.0
PYH2_k127_5516782_5 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000008545 155.0
PYH2_k127_5516782_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000004075 131.0
PYH2_k127_5516782_7 - - - - 0.0000000000000000000000000000001301 127.0
PYH2_k127_5516782_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000001574 123.0
PYH2_k127_5516782_9 - - - - 0.0000000000000000000003101 98.0
PYH2_k127_554879_0 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000003009 118.0
PYH2_k127_554879_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000178 61.0
PYH2_k127_555598_0 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000004758 223.0
PYH2_k127_555598_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000145 165.0
PYH2_k127_555598_2 Ferric uptake regulator family K03711 - - 0.000000000000000003327 90.0
PYH2_k127_555598_3 methyltransferase activity - - - 0.00000598 52.0
PYH2_k127_555598_4 FeoA K04758 - - 0.0001125 48.0
PYH2_k127_555893_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 345.0
PYH2_k127_555893_1 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002181 275.0
PYH2_k127_555893_2 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000224 227.0
PYH2_k127_555893_3 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000001558 183.0
PYH2_k127_555893_4 - - - - 0.000000000000000000000000000000000000000000000006482 179.0
PYH2_k127_555893_5 - - - - 0.0000000000737 66.0
PYH2_k127_555893_6 Domain of unknown function DUF11 - - - 0.0000003973 60.0
PYH2_k127_555893_7 Mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0005016 42.0
PYH2_k127_5608950_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 548.0
PYH2_k127_5608950_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 444.0
PYH2_k127_5608950_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 353.0
PYH2_k127_5608950_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 268.0
PYH2_k127_5608950_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000001089 198.0
PYH2_k127_5608950_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000004774 178.0
PYH2_k127_5608950_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000001982 81.0
PYH2_k127_5608950_7 membrane protein (DUF2078) K08982 - - 0.000000004748 63.0
PYH2_k127_5609100_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 432.0
PYH2_k127_5609100_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000006375 267.0
PYH2_k127_5609100_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000005541 145.0
PYH2_k127_5609100_3 Protein conserved in bacteria - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.00000005664 65.0
PYH2_k127_5615343_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 300.0
PYH2_k127_5615343_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000004046 179.0
PYH2_k127_5615427_0 fructosamine-3-kinase activity - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 290.0
PYH2_k127_5615427_1 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000001904 175.0
PYH2_k127_5615427_2 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000001317 175.0
PYH2_k127_5615427_3 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000058 134.0
PYH2_k127_5615427_4 Xylose isomerase - - - 0.0000000000000000000000009645 114.0
PYH2_k127_5615427_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000004298 87.0
PYH2_k127_5615427_6 - - - - 0.000004374 58.0
PYH2_k127_5617802_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 471.0
PYH2_k127_5617802_1 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 412.0
PYH2_k127_5617802_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 271.0
PYH2_k127_5617802_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
PYH2_k127_5617802_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
PYH2_k127_5617802_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000006124 247.0
PYH2_k127_5617802_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000182 246.0
PYH2_k127_5621562_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 489.0
PYH2_k127_5621562_1 SMART Nucleotide binding protein, PINc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 356.0
PYH2_k127_5621562_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 268.0
PYH2_k127_5621562_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000003329 179.0
PYH2_k127_5622821_0 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 295.0
PYH2_k127_5622821_1 S-layer homology domain K01181,K01186,K12373,K20276 - 3.2.1.18,3.2.1.52,3.2.1.8 0.000000000000000000004032 106.0
PYH2_k127_5622821_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000001197 55.0
PYH2_k127_5635419_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 246.0
PYH2_k127_5635419_1 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000003128 142.0
PYH2_k127_5639868_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 342.0
PYH2_k127_5639868_1 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 332.0
PYH2_k127_5639868_2 helix_turn _helix lactose operon repressor K05499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
PYH2_k127_5639868_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005554 241.0
PYH2_k127_5639868_4 LysM domain - - - 0.00000000000000000000000007952 118.0
PYH2_k127_5643901_0 ABC transporter transmembrane region K06147 - - 4.38e-275 857.0
PYH2_k127_5643901_1 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 318.0
PYH2_k127_5643901_2 GIY-YIG catalytic domain K07461 - - 0.000002515 51.0
PYH2_k127_5644054_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 357.0
PYH2_k127_5644054_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000002482 137.0
PYH2_k127_5644054_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000004283 63.0
PYH2_k127_5644054_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00002079 57.0
PYH2_k127_5644054_4 Histidine kinase - - - 0.0002934 48.0
PYH2_k127_5649595_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 360.0
PYH2_k127_5649595_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 321.0
PYH2_k127_5649595_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
PYH2_k127_5649595_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 324.0
PYH2_k127_5649595_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000003197 246.0
PYH2_k127_5649595_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000001974 223.0
PYH2_k127_5649595_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000002987 160.0
PYH2_k127_5649595_7 Bacterial regulatory helix-turn-helix protein, lysR family K02019,K05772 - - 0.000000000000000000000000009053 113.0
PYH2_k127_5659340_0 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001009 289.0
PYH2_k127_5659340_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008426 254.0
PYH2_k127_5659340_2 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000003727 203.0
PYH2_k127_5659340_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000003706 197.0
PYH2_k127_5659340_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000009073 205.0
PYH2_k127_5659340_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000005226 171.0
PYH2_k127_5659340_6 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000000000000000002971 149.0
PYH2_k127_5659440_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 533.0
PYH2_k127_5659440_1 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008309 284.0
PYH2_k127_5659440_2 - - - - 0.0000000000005406 72.0
PYH2_k127_5659440_3 COG3415 Transposase and inactivated derivatives - - - 0.0000007628 57.0
PYH2_k127_5661307_0 Nickel-dependent hydrogenase K15830 - - 1.185e-228 722.0
PYH2_k127_5661307_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 0.000000000000000000000000000000000000002422 152.0
PYH2_k127_5670583_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 574.0
PYH2_k127_5670583_1 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 290.0
PYH2_k127_5672237_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000903 214.0
PYH2_k127_5672237_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000056 208.0
PYH2_k127_5672237_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000403 74.0
PYH2_k127_5672237_3 Membrane - - - 0.000001468 62.0
PYH2_k127_5673195_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 502.0
PYH2_k127_5673195_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000009968 193.0
PYH2_k127_5673195_2 Domain of unknown function (DUF3368) K07066 - - 0.0000004965 54.0
PYH2_k127_5673195_3 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00003364 46.0
PYH2_k127_5686706_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000002495 139.0
PYH2_k127_5686706_1 - - - - 0.0000000000000000000000000000003956 132.0
PYH2_k127_5686706_3 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000000002467 70.0
PYH2_k127_5686706_4 - - - - 0.00000002256 63.0
PYH2_k127_5686706_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0004153 49.0
PYH2_k127_5686737_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.793e-263 820.0
PYH2_k127_5686737_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 368.0
PYH2_k127_5686737_2 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
PYH2_k127_5686737_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000002395 181.0
PYH2_k127_5686873_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 1.017e-241 762.0
PYH2_k127_5686873_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 569.0
PYH2_k127_5686873_10 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000001087 151.0
PYH2_k127_5686873_11 PQQ enzyme repeat - - - 0.00000000000000000000000000000001854 141.0
PYH2_k127_5686873_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002382 111.0
PYH2_k127_5686873_13 - - - - 0.0000000000000000000009574 107.0
PYH2_k127_5686873_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000003849 91.0
PYH2_k127_5686873_16 PFAM peptidase S58, DmpA - - - 0.0000000000108 65.0
PYH2_k127_5686873_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000007581 59.0
PYH2_k127_5686873_2 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 406.0
PYH2_k127_5686873_3 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 291.0
PYH2_k127_5686873_4 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 292.0
PYH2_k127_5686873_5 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008414 252.0
PYH2_k127_5686873_6 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004203 250.0
PYH2_k127_5686873_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001169 234.0
PYH2_k127_5686873_8 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.0000000000000000000000000000000000000000000005474 176.0
PYH2_k127_5686873_9 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000000000000000003869 160.0
PYH2_k127_5688100_0 dehydrogenase, E1 component K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 463.0
PYH2_k127_5688100_1 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 301.0
PYH2_k127_5688100_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000662 281.0
PYH2_k127_5688100_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000003193 258.0
PYH2_k127_5688100_4 S4 domain K14761 - - 0.0000000000000000007523 87.0
PYH2_k127_5688100_5 - - - - 0.000000005429 65.0
PYH2_k127_5696303_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.988e-259 811.0
PYH2_k127_5696303_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 336.0
PYH2_k127_5696303_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000002935 232.0
PYH2_k127_5696303_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000006726 206.0
PYH2_k127_5696303_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002261 144.0
PYH2_k127_5696303_5 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000004014 143.0
PYH2_k127_5696303_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002393 78.0
PYH2_k127_5740938_0 Histidine kinase-like ATPases - - - 5.354e-225 787.0
PYH2_k127_5740938_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005877 279.0
PYH2_k127_5740938_2 Transposase K07491 - - 0.00000002429 57.0
PYH2_k127_5745110_0 Molecular chaperone. Has ATPase activity K04079 - - 1.711e-194 621.0
PYH2_k127_5745110_1 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000006411 113.0
PYH2_k127_5748813_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 375.0
PYH2_k127_5748813_1 - - - - 0.0000001288 54.0
PYH2_k127_5750071_0 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
PYH2_k127_5750071_1 Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.000000000000000000000000000000004016 142.0
PYH2_k127_5750071_2 PFAM cyclic nucleotide-binding - - - 0.00000000000000000000000002117 114.0
PYH2_k127_5750604_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 557.0
PYH2_k127_5750604_1 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000003276 161.0
PYH2_k127_5755348_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 571.0
PYH2_k127_5755763_0 Serine threonine protein kinase K12132 - 2.7.11.1 1.397e-218 694.0
PYH2_k127_5755763_1 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 323.0
PYH2_k127_5755763_2 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 319.0
PYH2_k127_5755763_3 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000002376 199.0
PYH2_k127_5755763_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000008576 198.0
PYH2_k127_5755763_5 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000002209 127.0
PYH2_k127_5755763_6 - - - - 0.000000000000000003324 87.0
PYH2_k127_5759864_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 542.0
PYH2_k127_5759864_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 534.0
PYH2_k127_5759864_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 384.0
PYH2_k127_5759864_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000003748 229.0
PYH2_k127_5759864_4 Hemerythrin HHE cation binding domain - - - 0.00000006802 61.0
PYH2_k127_5769397_0 Rad50 zinc hook motif K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 364.0
PYH2_k127_5769397_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 296.0
PYH2_k127_5769397_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000001063 196.0
PYH2_k127_5770760_0 PFAM GDSL-like Lipase Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000004661 225.0
PYH2_k127_5770760_1 Haem-binding domain - - - 0.00000000000000000000000000000000000000000007626 164.0
PYH2_k127_5770760_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001856 151.0
PYH2_k127_5770760_3 4-vinyl reductase, 4VR K07013,K17763 - - 0.00000000000000000000000000000007318 132.0
PYH2_k127_5770760_5 Putative phosphatase (DUF442) - - - 0.00008661 46.0
PYH2_k127_5773617_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.949e-197 642.0
PYH2_k127_5773617_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000001135 197.0
PYH2_k127_5776136_0 ABC transporter transmembrane region K06147 - - 9.999e-250 783.0
PYH2_k127_5776136_1 stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000005679 176.0
PYH2_k127_5800269_0 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000003493 211.0
PYH2_k127_5800269_1 SnoaL-like polyketide cyclase - - - 0.0000000003705 66.0
PYH2_k127_5800269_2 Tetratricopeptide repeat - - - 0.00004456 48.0
PYH2_k127_5814414_0 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 401.0
PYH2_k127_5814414_1 Arabinose efflux permease family protein - - - 0.0000000000000000000000008132 119.0
PYH2_k127_5814414_2 Protein of unknown function DUF58 - - - 0.0000000000000000000006034 100.0
PYH2_k127_5837555_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
PYH2_k127_5837555_1 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 318.0
PYH2_k127_5837555_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 316.0
PYH2_k127_5837555_3 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000001141 176.0
PYH2_k127_5837555_4 NTPase - - - 0.0000000000000000000000000004672 119.0
PYH2_k127_5841089_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1223.0
PYH2_k127_5841089_1 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 405.0
PYH2_k127_5841089_10 DDE_Tnp_1-associated - - - 0.00001595 48.0
PYH2_k127_5841089_2 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 331.0
PYH2_k127_5841089_3 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 308.0
PYH2_k127_5841089_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 304.0
PYH2_k127_5841089_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003205 247.0
PYH2_k127_5841089_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000001351 196.0
PYH2_k127_5841089_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000001143 104.0
PYH2_k127_5841089_8 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000003064 92.0
PYH2_k127_5841089_9 DDE_Tnp_1-associated - - - 0.000004603 51.0
PYH2_k127_5857257_0 - - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
PYH2_k127_5857257_1 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000003045 154.0
PYH2_k127_5857257_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000002971 149.0
PYH2_k127_5858811_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K00773,K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29,2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 375.0
PYH2_k127_5858811_1 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001002 258.0
PYH2_k127_5858811_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000005695 171.0
PYH2_k127_5858811_3 Protein of unknown function (DUF2905) - - - 0.00000000006455 65.0
PYH2_k127_5863007_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 379.0
PYH2_k127_5863007_1 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 301.0
PYH2_k127_5863007_2 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002333 269.0
PYH2_k127_5863007_3 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000004192 243.0
PYH2_k127_5863007_4 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000005449 175.0
PYH2_k127_5863007_5 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000004491 161.0
PYH2_k127_5863007_6 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000001417 158.0
PYH2_k127_5863007_7 OsmC-like protein K07397 - - 0.00000000000000000000000000009757 121.0
PYH2_k127_5863007_8 DNA-binding transcription factor activity K03892,K21903 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000166 108.0
PYH2_k127_5863007_9 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000005313 75.0
PYH2_k127_5872593_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 321.0
PYH2_k127_5872593_1 PFAM membrane-flanked domain - - - 0.00000000000000000000000000000000000002032 152.0
PYH2_k127_5872593_2 - - - - 0.000008046 56.0
PYH2_k127_5884413_0 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001228 246.0
PYH2_k127_5900402_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 430.0
PYH2_k127_5900402_1 Histidine kinase - - - 0.00000006091 59.0
PYH2_k127_5900402_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000001621 60.0
PYH2_k127_5900402_3 Bacterial Ig-like domain - - - 0.00000114 54.0
PYH2_k127_5900402_4 - - - - 0.00001808 52.0
PYH2_k127_5901621_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 460.0
PYH2_k127_5901621_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000003293 120.0
PYH2_k127_5901621_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000001287 110.0
PYH2_k127_5904050_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 411.0
PYH2_k127_5904050_1 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 312.0
PYH2_k127_5904050_2 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 279.0
PYH2_k127_5906412_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2e-323 1010.0
PYH2_k127_5906412_1 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000004192 104.0
PYH2_k127_5906412_2 Domains REC, sigma54 interaction, HTH8 - - - 0.00003588 48.0
PYH2_k127_5920701_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 555.0
PYH2_k127_5920701_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 414.0
PYH2_k127_5920701_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000003988 61.0
PYH2_k127_5949448_0 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 350.0
PYH2_k127_5949448_1 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 289.0
PYH2_k127_5949448_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001438 246.0
PYH2_k127_5949448_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000004563 215.0
PYH2_k127_5949448_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000001712 198.0
PYH2_k127_5949448_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000007853 184.0
PYH2_k127_5949448_6 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000000000004263 134.0
PYH2_k127_5949448_7 metal-dependent membrane protease K07052 - - 0.00000000000000000000000000001333 129.0
PYH2_k127_5949448_8 peptidase - - - 0.000003532 55.0
PYH2_k127_5949448_9 - - - - 0.0004348 51.0
PYH2_k127_5956974_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001555 74.0
PYH2_k127_5956974_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000004944 54.0
PYH2_k127_5960196_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 607.0
PYH2_k127_5960196_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 435.0
PYH2_k127_5960196_2 PFAM ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
PYH2_k127_6006877_0 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 411.0
PYH2_k127_6006877_1 lipolytic protein G-D-S-L family K01179,K01183 - 3.2.1.14,3.2.1.4 0.000001529 50.0
PYH2_k127_6023153_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000001137 215.0
PYH2_k127_6023153_1 Serine aminopeptidase, S33 - - - 0.000000000000000000002145 104.0
PYH2_k127_6060772_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 489.0
PYH2_k127_6060772_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 412.0
PYH2_k127_6060772_10 NUDIX domain - - - 0.000000000000000000006552 96.0
PYH2_k127_6060772_11 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000001917 81.0
PYH2_k127_6060772_12 - - - - 0.000000000222 69.0
PYH2_k127_6060772_2 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 370.0
PYH2_k127_6060772_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 340.0
PYH2_k127_6060772_4 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 327.0
PYH2_k127_6060772_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 303.0
PYH2_k127_6060772_6 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000005542 244.0
PYH2_k127_6060772_7 Kelch repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000178 221.0
PYH2_k127_6060772_8 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000005313 180.0
PYH2_k127_6060772_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000002045 175.0
PYH2_k127_6105941_0 AMP-binding enzyme C-terminal domain K02363,K04116 - 2.7.7.58,6.3.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 541.0
PYH2_k127_6105941_1 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 423.0
PYH2_k127_6105941_2 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000004026 212.0
PYH2_k127_6105941_3 Protein of unknown function (DUF1475) - - - 0.00000000000000000000000000000000002051 137.0
PYH2_k127_6105941_4 - - - - 0.0000000000000004454 83.0
PYH2_k127_6105941_6 PFAM secretion protein HlyD family protein K01993 - - 0.000007976 48.0
PYH2_k127_613168_0 PFAM ABC transporter related K02049,K15555,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 454.0
PYH2_k127_613168_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 318.0
PYH2_k127_613168_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000003875 143.0
PYH2_k127_613168_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00390 - 1.8.4.10,1.8.4.8 0.00000001412 60.0
PYH2_k127_6167361_0 PFAM glycosyl transferase, family 51 - - - 3.629e-225 723.0
PYH2_k127_6167361_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.368e-209 658.0
PYH2_k127_6167361_10 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000006832 227.0
PYH2_k127_6167361_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000003081 207.0
PYH2_k127_6167361_12 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000000000000000000718 173.0
PYH2_k127_6167361_13 PFAM lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000004395 123.0
PYH2_k127_6167361_14 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000002591 88.0
PYH2_k127_6167361_16 - - - - 0.00000000248 62.0
PYH2_k127_6167361_18 Putative zinc-finger - - - 0.00003173 55.0
PYH2_k127_6167361_19 Capsular exopolysaccharide family - - - 0.0002943 51.0
PYH2_k127_6167361_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 593.0
PYH2_k127_6167361_20 domain protein - - - 0.0003696 50.0
PYH2_k127_6167361_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 439.0
PYH2_k127_6167361_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 437.0
PYH2_k127_6167361_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 359.0
PYH2_k127_6167361_6 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 339.0
PYH2_k127_6167361_7 PFAM Shikimate quinate 5-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 304.0
PYH2_k127_6167361_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 273.0
PYH2_k127_6167361_9 TIGRFAM capsular exopolysaccharide family K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
PYH2_k127_618259_0 Associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 468.0
PYH2_k127_618259_1 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 419.0
PYH2_k127_6219182_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0 1095.0
PYH2_k127_6219182_1 alpha amylase catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000002914 213.0
PYH2_k127_622101_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 311.0
PYH2_k127_622101_1 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000001147 138.0
PYH2_k127_6256885_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 445.0
PYH2_k127_6256885_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 - 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 322.0
PYH2_k127_6256885_2 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000001285 213.0
PYH2_k127_6261815_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 355.0
PYH2_k127_6305541_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 477.0
PYH2_k127_6305541_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 458.0
PYH2_k127_6305541_2 Fe-S oxidoreductases K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 414.0
PYH2_k127_6305541_3 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 337.0
PYH2_k127_6305541_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
PYH2_k127_6305541_5 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000002598 218.0
PYH2_k127_6305541_6 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.000000000000000000000000000000000000000000000000000000000004004 217.0
PYH2_k127_6305541_7 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000007027 158.0
PYH2_k127_63231_0 Heat shock 70 kDa protein K04043 - - 1.171e-287 895.0
PYH2_k127_63231_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 629.0
PYH2_k127_63231_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000003476 140.0
PYH2_k127_63231_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000004129 149.0
PYH2_k127_63231_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000005588 116.0
PYH2_k127_63231_13 aminoglycoside K00662 - 2.3.1.81 0.00000000000000000001282 93.0
PYH2_k127_63231_14 PFAM Propeptide, PepSY amd peptidase M4 - - - 0.00000000000000000002284 98.0
PYH2_k127_63231_15 - - - - 0.0000002007 55.0
PYH2_k127_63231_16 Golgi vesicle prefusion complex stabilization K19373 GO:0000301,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006810,GO:0006890,GO:0006891,GO:0006996,GO:0007030,GO:0008150,GO:0009987,GO:0010256,GO:0012505,GO:0016043,GO:0016192,GO:0017119,GO:0022607,GO:0032991,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0048193,GO:0048213,GO:0051179,GO:0051234,GO:0065003,GO:0071840,GO:0099023 - 0.0000004049 57.0
PYH2_k127_63231_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 454.0
PYH2_k127_63231_3 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 370.0
PYH2_k127_63231_4 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 339.0
PYH2_k127_63231_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 334.0
PYH2_k127_63231_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 311.0
PYH2_k127_63231_7 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
PYH2_k127_63231_8 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002192 268.0
PYH2_k127_63231_9 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 266.0
PYH2_k127_63364_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 484.0
PYH2_k127_63364_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 335.0
PYH2_k127_63364_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000001832 213.0
PYH2_k127_63364_3 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000001727 192.0
PYH2_k127_63364_5 - - - - 0.0005866 53.0
PYH2_k127_6360931_0 Histidine kinase - - - 0.00000000000005804 85.0
PYH2_k127_6360931_1 Transcriptional regulatory protein, C terminal K07665 - - 0.00007285 51.0
PYH2_k127_6419831_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 7.949e-196 620.0
PYH2_k127_6419831_1 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 486.0
PYH2_k127_6419831_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 293.0
PYH2_k127_6419831_3 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000012 179.0
PYH2_k127_6432850_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 394.0
PYH2_k127_6432850_1 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000000005533 158.0
PYH2_k127_6432850_2 JAB/MPN domain - - - 0.0000000000000000000000000000002698 127.0
PYH2_k127_6432850_3 ThiS family K03636 - - 0.000000000000000000000000000003674 121.0
PYH2_k127_6432850_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0001545 47.0
PYH2_k127_6459891_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 500.0
PYH2_k127_6459891_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000001056 228.0
PYH2_k127_6459891_2 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000004446 173.0
PYH2_k127_6459891_3 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000002 102.0
PYH2_k127_6459891_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000024 92.0
PYH2_k127_6544714_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 472.0
PYH2_k127_6544714_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000001415 184.0
PYH2_k127_6544714_2 AAA domain K02282 - - 0.00000000000000000000000000000000000823 150.0
PYH2_k127_6544714_3 Microcompartments protein - - - 0.0000000000000000000000000001797 123.0
PYH2_k127_6544714_4 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000005269 61.0
PYH2_k127_6546578_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 307.0
PYH2_k127_6546578_1 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000193 185.0
PYH2_k127_6546578_2 Histidine kinase K07636 - 2.7.13.3 0.000000007438 57.0
PYH2_k127_6547415_0 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000007394 106.0
PYH2_k127_6547415_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000007734 113.0
PYH2_k127_6571813_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000005165 198.0
PYH2_k127_6571813_1 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000003476 166.0
PYH2_k127_6571813_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000001332 180.0
PYH2_k127_6571813_3 domain, Protein - - - 0.0000000000000000000000000000001033 139.0
PYH2_k127_6573394_0 Belongs to the Pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 306.0
PYH2_k127_6573394_1 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000001285 192.0
PYH2_k127_6573394_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000002997 126.0
PYH2_k127_6573394_5 - - - - 0.00003726 47.0
PYH2_k127_6574111_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 613.0
PYH2_k127_6574111_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000002568 170.0
PYH2_k127_6574111_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000001106 151.0
PYH2_k127_6574111_3 Transcriptional regulator, arsR family - - - 0.0000000000000000000000002353 109.0
PYH2_k127_6574111_4 - - - - 0.0000000000000000000000007804 116.0
PYH2_k127_6576482_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.647e-213 676.0
PYH2_k127_6576482_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 336.0
PYH2_k127_6576482_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
PYH2_k127_6576482_3 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000002484 111.0
PYH2_k127_6576482_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000001168 76.0
PYH2_k127_6580814_0 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 413.0
PYH2_k127_6580814_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 410.0
PYH2_k127_6580814_2 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001797 248.0
PYH2_k127_6580814_3 Phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000005775 159.0
PYH2_k127_6580814_4 acetyltransferase - - - 0.0000000000000000000000002797 109.0
PYH2_k127_6580814_5 Dual specificity phosphatase, catalytic domain K14819 GO:0000003,GO:0000027,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0008138,GO:0008150,GO:0008152,GO:0009272,GO:0009653,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010494,GO:0010506,GO:0010508,GO:0010638,GO:0010927,GO:0016043,GO:0016239,GO:0016241,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030154,GO:0030435,GO:0030437,GO:0030476,GO:0030684,GO:0030687,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0032991,GO:0033043,GO:0034293,GO:0034622,GO:0035335,GO:0035556,GO:0035770,GO:0036211,GO:0036464,GO:0042244,GO:0042254,GO:0042255,GO:0042273,GO:0042546,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0043935,GO:0044085,GO:0044087,GO:0044088,GO:0044089,GO:0044090,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045229,GO:0048468,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051321,GO:0051704,GO:0051716,GO:0065003,GO:0065007,GO:0070590,GO:0070591,GO:0070726,GO:0070925,GO:0071554,GO:0071555,GO:0071704,GO:0071826,GO:0071840,GO:0071852,GO:0071940,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1903046,GO:1990904,GO:2000785,GO:2000786 3.1.3.16,3.1.3.48 0.00000000005562 72.0
PYH2_k127_6580858_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 355.0
PYH2_k127_6580858_1 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000002079 230.0
PYH2_k127_6580858_2 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000000004776 181.0
PYH2_k127_6580858_3 Rhodanese domain protein - - - 0.0000000000000000000000002177 108.0
PYH2_k127_6580858_4 META domain - - - 0.00000000004973 68.0
PYH2_k127_6584704_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 433.0
PYH2_k127_6584704_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 413.0
PYH2_k127_6584704_10 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000001065 210.0
PYH2_k127_6584704_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002372 199.0
PYH2_k127_6584704_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000003101 196.0
PYH2_k127_6584704_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000004062 196.0
PYH2_k127_6584704_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000007451 194.0
PYH2_k127_6584704_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000002829 193.0
PYH2_k127_6584704_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001284 185.0
PYH2_k127_6584704_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000003812 179.0
PYH2_k127_6584704_18 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001739 173.0
PYH2_k127_6584704_19 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000003754 159.0
PYH2_k127_6584704_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 403.0
PYH2_k127_6584704_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000001678 154.0
PYH2_k127_6584704_21 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001574 140.0
PYH2_k127_6584704_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000005088 134.0
PYH2_k127_6584704_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000004829 128.0
PYH2_k127_6584704_24 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001887 128.0
PYH2_k127_6584704_25 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000003328 117.0
PYH2_k127_6584704_26 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002723 111.0
PYH2_k127_6584704_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000007851 95.0
PYH2_k127_6584704_28 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000002888 96.0
PYH2_k127_6584704_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001846 91.0
PYH2_k127_6584704_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 273.0
PYH2_k127_6584704_30 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000008303 78.0
PYH2_k127_6584704_31 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001419 70.0
PYH2_k127_6584704_32 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000003265 66.0
PYH2_k127_6584704_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
PYH2_k127_6584704_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 261.0
PYH2_k127_6584704_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001882 258.0
PYH2_k127_6584704_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000005811 246.0
PYH2_k127_6584704_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
PYH2_k127_6584704_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000004669 229.0
PYH2_k127_6591198_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.535e-204 644.0
PYH2_k127_6591198_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 531.0
PYH2_k127_6591198_10 PFAM aldo keto reductase - - - 0.000601 43.0
PYH2_k127_6591198_2 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 506.0
PYH2_k127_6591198_3 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 386.0
PYH2_k127_6591198_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 354.0
PYH2_k127_6591198_5 Protein of unknown function (DUF1361) - - - 0.000000000000000000000000000000000000000000008032 171.0
PYH2_k127_6591198_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000001648 147.0
PYH2_k127_6591198_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000002407 110.0
PYH2_k127_6591198_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000007972 98.0
PYH2_k127_6591198_9 CarD family transcriptional regulator K07736 - - 0.0000000009644 66.0
PYH2_k127_6597922_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 494.0
PYH2_k127_6597922_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008122 269.0
PYH2_k127_6597922_2 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000001325 162.0
PYH2_k127_6603501_0 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 343.0
PYH2_k127_6603501_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000002282 257.0
PYH2_k127_6604452_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.782e-196 637.0
PYH2_k127_6604452_1 Nucleoside H+ symporter K05820 - - 0.00000000000000000001297 102.0
PYH2_k127_6604452_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000003352 81.0
PYH2_k127_6606892_0 Bacterial extracellular solute-binding protein K02055,K11069 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 584.0
PYH2_k127_6606892_1 ATPase activity K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 456.0
PYH2_k127_6606892_2 PFAM binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 397.0
PYH2_k127_6606892_3 ABC transporter (permease) K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 359.0
PYH2_k127_6606892_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 320.0
PYH2_k127_6606892_5 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 306.0
PYH2_k127_6606892_6 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000002401 90.0
PYH2_k127_6606892_7 - - - - 0.000003349 51.0
PYH2_k127_6606892_8 STAS domain - - - 0.00007818 50.0
PYH2_k127_6606892_9 Acetyltransferase (GNAT) domain - - - 0.000945 43.0
PYH2_k127_6609248_0 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005464 270.0
PYH2_k127_6609248_1 Ser Thr phosphatase family protein K07098 - - 0.0000228 55.0
PYH2_k127_6618458_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 1.707e-214 676.0
PYH2_k127_6618458_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K02827 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 615.0
PYH2_k127_6618458_10 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000072 59.0
PYH2_k127_6618458_11 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00008506 49.0
PYH2_k127_6618458_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 443.0
PYH2_k127_6618458_3 Peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 406.0
PYH2_k127_6618458_4 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 302.0
PYH2_k127_6618458_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 296.0
PYH2_k127_6618458_6 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000008205 228.0
PYH2_k127_6618458_7 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000001238 164.0
PYH2_k127_6618458_8 Protein of unknown function (DUF1706) - - - 0.000000000000000002048 91.0
PYH2_k127_6618458_9 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000001388 79.0
PYH2_k127_6619644_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000006964 203.0
PYH2_k127_6619644_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000004018 108.0
PYH2_k127_6619644_2 Membrane - - - 0.0000000000000000000002603 98.0
PYH2_k127_6619644_3 Participates in initiation and elongation during chromosome replication K02314,K02316 - 3.6.4.12 0.00000000000000007147 90.0
PYH2_k127_6621168_0 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 341.0
PYH2_k127_6621168_1 Helicase conserved C-terminal domain - - - 0.000000000000000000000000000001672 133.0
PYH2_k127_6621168_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000001348 74.0
PYH2_k127_6621589_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 536.0
PYH2_k127_6621589_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 319.0
PYH2_k127_6621589_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 318.0
PYH2_k127_6621589_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007462 283.0
PYH2_k127_6621589_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000005819 207.0
PYH2_k127_6621589_5 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000002082 213.0
PYH2_k127_6621589_6 Histidine kinase K00936,K02030 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000177 207.0
PYH2_k127_6621589_7 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000000000000000000000000000001349 130.0
PYH2_k127_6621589_8 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00007774 45.0
PYH2_k127_6627968_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 435.0
PYH2_k127_6627968_1 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 367.0
PYH2_k127_6627968_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 305.0
PYH2_k127_6627968_3 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 301.0
PYH2_k127_6627968_4 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001042 287.0
PYH2_k127_6627968_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 278.0
PYH2_k127_6627968_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000003327 242.0
PYH2_k127_6627968_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000007999 232.0
PYH2_k127_6630386_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.858e-284 903.0
PYH2_k127_6630386_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 581.0
PYH2_k127_6630386_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 372.0
PYH2_k127_6630386_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 326.0
PYH2_k127_6630386_4 regulation of circadian rhythm K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 286.0
PYH2_k127_6630386_5 phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000000000000000000000002788 125.0
PYH2_k127_6637678_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 437.0
PYH2_k127_6637678_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000008133 235.0
PYH2_k127_6637678_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000002057 132.0
PYH2_k127_6637678_3 Major Facilitator Superfamily K18214 - - 0.00000001602 57.0
PYH2_k127_6637678_4 CHAT domain - - - 0.0006272 49.0
PYH2_k127_6638702_0 PFAM BMC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 306.0
PYH2_k127_6638702_1 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 301.0
PYH2_k127_6638702_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004355 273.0
PYH2_k127_6638702_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000009028 231.0
PYH2_k127_6638702_4 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000001542 177.0
PYH2_k127_6638702_5 Ribose/Galactose Isomerase K01808,K01819 - 5.3.1.26,5.3.1.6 0.00000000000000000000000000000000000000000001165 172.0
PYH2_k127_6638702_6 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.00000000000000000000000000000000000000002962 160.0
PYH2_k127_6638702_7 BMC K04027 - - 0.0000000000000000000000000000000000001961 143.0
PYH2_k127_6638702_8 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000000000004612 124.0
PYH2_k127_6638702_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000009061 58.0
PYH2_k127_6667630_0 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 547.0
PYH2_k127_6667630_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 325.0
PYH2_k127_6667630_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000007029 223.0
PYH2_k127_6667630_3 formate dehydrogenase (NAD+) activity - - - 0.0000000000000000000000000000000000000000000000000009929 183.0
PYH2_k127_6667630_4 domain, Protein K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00003848 52.0
PYH2_k127_6675442_0 Oligopeptidase F K08602 - - 5.047e-225 712.0
PYH2_k127_6675442_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 419.0
PYH2_k127_6675442_2 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007133 286.0
PYH2_k127_6675442_3 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.0000000000000000000000000000000000000001415 161.0
PYH2_k127_6675442_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000002143 155.0
PYH2_k127_6675442_5 - - - - 0.000000000000000000000000000000001506 136.0
PYH2_k127_6675442_6 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.000000000000003152 83.0
PYH2_k127_6675442_7 ABC-2 type transporter K01992 - - 0.000000003845 63.0
PYH2_k127_6678939_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 445.0
PYH2_k127_6678939_1 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002837 240.0
PYH2_k127_6678939_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000245 182.0
PYH2_k127_6678939_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000007535 173.0
PYH2_k127_6678939_4 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000003649 130.0
PYH2_k127_6685266_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005521 274.0
PYH2_k127_6685266_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003111 257.0
PYH2_k127_6685266_2 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.00000000000000000000000000000000000000000000001192 176.0
PYH2_k127_6685266_3 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000003057 169.0
PYH2_k127_6685266_4 Phenylacetate-CoA oxygenase K02611 - 1.14.13.149 0.000000000000000000000001447 107.0
PYH2_k127_6685266_5 Belongs to the peptidase S8 family - - - 0.000000000000001407 88.0
PYH2_k127_6689874_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
PYH2_k127_6689874_1 extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000004759 130.0
PYH2_k127_6708774_0 helix_turn_helix, Lux Regulon K03556 - - 0.0 1088.0
PYH2_k127_6708774_1 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 464.0
PYH2_k127_6708774_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 398.0
PYH2_k127_6708774_3 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006961 282.0
PYH2_k127_6708774_4 - - - - 0.000000000000000000000000971 108.0
PYH2_k127_6708774_5 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000001334 87.0
PYH2_k127_6712601_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 588.0
PYH2_k127_6712601_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006439 242.0
PYH2_k127_6712601_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001188 219.0
PYH2_k127_6712601_3 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000434 201.0
PYH2_k127_6712601_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000001213 184.0
PYH2_k127_6712601_5 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000001253 81.0
PYH2_k127_6714221_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 496.0
PYH2_k127_6714221_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 457.0
PYH2_k127_6714221_11 Membrane - - - 0.00000000006646 76.0
PYH2_k127_6714221_2 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 454.0
PYH2_k127_6714221_3 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 441.0
PYH2_k127_6714221_4 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 307.0
PYH2_k127_6714221_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006505 232.0
PYH2_k127_6714221_6 Ndr family - - - 0.000000000000000000000000000000000000000000000000000000000000002235 226.0
PYH2_k127_6714221_7 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000154 184.0
PYH2_k127_6714221_8 Protein of unknown function (DUF2723) K14340 - - 0.00000000000000000000000000000000003605 156.0
PYH2_k127_6714221_9 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000001208 96.0
PYH2_k127_6722558_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 531.0
PYH2_k127_6722558_1 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13328 - 1.17.1.1,4.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 494.0
PYH2_k127_6722558_10 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000009755 93.0
PYH2_k127_6722558_11 - - - - 0.00000000000000007525 85.0
PYH2_k127_6722558_12 STAS domain - - - 0.0000000002147 66.0
PYH2_k127_6722558_2 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 484.0
PYH2_k127_6722558_3 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 400.0
PYH2_k127_6722558_4 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 309.0
PYH2_k127_6722558_5 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 297.0
PYH2_k127_6722558_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000002235 266.0
PYH2_k127_6722558_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000007538 192.0
PYH2_k127_6722558_8 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000001774 164.0
PYH2_k127_6722558_9 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000164 130.0
PYH2_k127_6722973_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1275.0
PYH2_k127_6722973_1 PFAM Tetratricopeptide repeat - - - 0.0 1117.0
PYH2_k127_6722973_2 Glycosyltransferase 36 associated - - - 0.0 1055.0
PYH2_k127_6722973_3 PFAM Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 526.0
PYH2_k127_6722973_4 Domain of unknown function (DUF4380) - - - 0.0000000000000000000000000000000000000000000000000002338 197.0
PYH2_k127_6722973_5 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.00000000000000000002618 91.0
PYH2_k127_6729787_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 303.0
PYH2_k127_6729787_1 PAS domain - - - 0.0000000000000000000000000000000000002953 144.0
PYH2_k127_6729787_2 Transcriptional activator - - - 0.00000000000000000828 90.0
PYH2_k127_6729787_3 TipAS antibiotic-recognition domain - - - 0.000000000000001737 77.0
PYH2_k127_6729787_4 PFAM Cell envelope-related transcriptional attenuator domain - - - 0.00001508 51.0
PYH2_k127_6769544_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005579 245.0
PYH2_k127_6769544_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000002788 196.0
PYH2_k127_6770936_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1164.0
PYH2_k127_6770936_1 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1051.0
PYH2_k127_6770936_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000007897 157.0
PYH2_k127_6770936_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000007586 150.0
PYH2_k127_6770936_12 Cyclic-di-AMP receptor - - - 0.000000000000000000000008034 104.0
PYH2_k127_6770936_13 TPR repeat - - - 0.0000000000006306 81.0
PYH2_k127_6770936_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000007631 54.0
PYH2_k127_6770936_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.203e-250 782.0
PYH2_k127_6770936_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 521.0
PYH2_k127_6770936_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 392.0
PYH2_k127_6770936_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 365.0
PYH2_k127_6770936_6 Psort location CytoplasmicMembrane, score K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 353.0
PYH2_k127_6770936_7 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000985 186.0
PYH2_k127_6770936_8 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000009229 159.0
PYH2_k127_6770936_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000004508 147.0
PYH2_k127_6771536_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 494.0
PYH2_k127_6771536_1 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 374.0
PYH2_k127_6771536_2 Belongs to the UPF0250 family K09158 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000003918 94.0
PYH2_k127_6771536_3 GrpB protein - - - 0.00000000000001671 80.0
PYH2_k127_6801727_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004993 259.0
PYH2_k127_6801727_1 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000001856 223.0
PYH2_k127_6801727_2 photosynthesis - - - 0.000001888 50.0
PYH2_k127_6845050_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 570.0
PYH2_k127_6845050_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
PYH2_k127_6845050_2 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000001501 79.0
PYH2_k127_6845050_3 Two component transcriptional regulator, LuxR family - - - 0.0000000002902 61.0
PYH2_k127_6852343_0 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000001348 175.0
PYH2_k127_6852343_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000001233 87.0
PYH2_k127_6852343_2 PBS lyase HEAT-like repeat - - - 0.00000000001098 73.0
PYH2_k127_6852343_3 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000006119 60.0
PYH2_k127_6852343_4 protein secretion K03116 - - 0.0000001212 58.0
PYH2_k127_6852343_5 LysM domain - - - 0.0000008417 60.0
PYH2_k127_6855000_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 507.0
PYH2_k127_6855000_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000002383 167.0
PYH2_k127_6860611_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.413e-269 862.0
PYH2_k127_6860611_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K02169,K02170,K08680,K10216,K15756,K16264 - 2.1.1.197,3.1.1.85,3.7.1.13,3.7.1.9,4.2.99.20 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
PYH2_k127_6860611_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000004446 174.0
PYH2_k127_6865229_0 EamA-like transporter family - - - 0.00000000000000000000000001614 114.0
PYH2_k127_6865229_1 transcriptional regulator - - - 0.0000000000003729 83.0
PYH2_k127_6894377_0 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 451.0
PYH2_k127_6894377_1 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001228 256.0
PYH2_k127_6894377_2 acetyltransferase K06889,K19273 - - 0.00000000000000000000000000001596 124.0
PYH2_k127_6909338_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 308.0
PYH2_k127_6909338_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 289.0
PYH2_k127_6909338_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000005321 200.0
PYH2_k127_6909338_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000003328 117.0
PYH2_k127_6909338_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000001279 105.0
PYH2_k127_6909338_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001131 91.0
PYH2_k127_6909338_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000006293 64.0
PYH2_k127_6909338_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000003869 62.0
PYH2_k127_6917527_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 483.0
PYH2_k127_6917527_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000009719 76.0
PYH2_k127_6957492_0 elongation factor Tu domain 2 protein K02355 - - 1.287e-250 791.0
PYH2_k127_6957492_1 - - - - 0.0000000199 61.0
PYH2_k127_6977543_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 538.0
PYH2_k127_6977543_1 lyase activity - - - 0.00000000000000000000000000000000000000000000000009549 184.0
PYH2_k127_6977543_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000002332 151.0
PYH2_k127_7010748_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.414e-245 773.0
PYH2_k127_7010748_1 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 610.0
PYH2_k127_7010748_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 424.0
PYH2_k127_7010748_3 TIGRFAM TIGR02453 family protein - - - 0.0000000000000000000000000000000000000000000000000000000002453 211.0
PYH2_k127_7010748_4 phosphoserine phosphatase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000008013 89.0
PYH2_k127_7010748_5 TIGRFAM TIGR02453 family protein - - - 0.00000000000003939 78.0
PYH2_k127_7010748_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000001207 69.0
PYH2_k127_7010748_7 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000005365 65.0
PYH2_k127_7040691_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000004712 212.0
PYH2_k127_7066842_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 458.0
PYH2_k127_7066842_1 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000001572 201.0
PYH2_k127_7069239_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 605.0
PYH2_k127_7069239_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000002294 210.0
PYH2_k127_7069239_2 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
PYH2_k127_7069239_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003279 168.0
PYH2_k127_7135978_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.976e-194 614.0
PYH2_k127_7135978_1 Phosphoribosylglycinamide synthetase, C domain K11788 GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 469.0
PYH2_k127_7135978_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 374.0
PYH2_k127_7135978_3 Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000001804 190.0
PYH2_k127_7135978_4 PFAM AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000003757 109.0
PYH2_k127_7182272_0 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 568.0
PYH2_k127_7182272_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
PYH2_k127_7182272_10 PFAM CBS domain containing protein - - - 0.000000000000000000000000000009592 124.0
PYH2_k127_7182272_11 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000000000001776 119.0
PYH2_k127_7182272_12 serine threonine protein kinase - - - 0.000000000000115 86.0
PYH2_k127_7182272_13 transcriptional regulator domain protein - - - 0.00000001559 65.0
PYH2_k127_7182272_14 - - - - 0.00007088 48.0
PYH2_k127_7182272_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 321.0
PYH2_k127_7182272_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006357 259.0
PYH2_k127_7182272_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000005673 233.0
PYH2_k127_7182272_5 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000006264 218.0
PYH2_k127_7182272_6 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000006709 207.0
PYH2_k127_7182272_7 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000168 197.0
PYH2_k127_7182272_8 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000001027 152.0
PYH2_k127_7182272_9 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000004175 143.0
PYH2_k127_7228649_0 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 307.0
PYH2_k127_7228649_1 response regulator, receiver K09763 - - 0.00000000000000000000000000000000000000007899 157.0
PYH2_k127_7228649_2 VIT family - - - 0.000000000000000000000000000000159 132.0
PYH2_k127_7251227_0 response to abiotic stimulus - - - 0.0000000000000000000000000000000000000000000000005455 182.0
PYH2_k127_7251227_1 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000536 147.0
PYH2_k127_7251227_2 - - - - 0.0000000000002844 74.0
PYH2_k127_7298568_0 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 4.672e-237 756.0
PYH2_k127_7298568_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 559.0
PYH2_k127_7298568_10 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000008543 199.0
PYH2_k127_7298568_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000009862 174.0
PYH2_k127_7298568_12 Flavin reductase like domain - - - 0.00000000000000000000000000000000000003334 149.0
PYH2_k127_7298568_13 CoA binding domain K06929 - - 0.000000000000000000000000000000000001832 145.0
PYH2_k127_7298568_14 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000000000001235 121.0
PYH2_k127_7298568_15 Cytochrome b(C-terminal)/b6/petD K03888 - - 0.000000000000000000000000002533 129.0
PYH2_k127_7298568_16 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000283 110.0
PYH2_k127_7298568_17 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000001827 91.0
PYH2_k127_7298568_18 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.0000000000000000004504 102.0
PYH2_k127_7298568_19 Acyl-ACP thioesterase - - - 0.000000000000000009268 94.0
PYH2_k127_7298568_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 557.0
PYH2_k127_7298568_20 TIGRFAM cytochrome C family protein - - - 0.00000000003832 74.0
PYH2_k127_7298568_21 cellulose binding - - - 0.0000006694 63.0
PYH2_k127_7298568_23 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000001536 61.0
PYH2_k127_7298568_24 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0001028 47.0
PYH2_k127_7298568_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 418.0
PYH2_k127_7298568_4 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 369.0
PYH2_k127_7298568_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 358.0
PYH2_k127_7298568_6 MFS_1 like family K08151,K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003907 290.0
PYH2_k127_7298568_7 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005042 243.0
PYH2_k127_7298568_8 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
PYH2_k127_7298568_9 COG0437 Fe-S-cluster-containing hydrogenase components 1 K00184 - - 0.0000000000000000000000000000000000000000000000000000000000008029 219.0
PYH2_k127_737620_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000009426 229.0
PYH2_k127_737620_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000005984 208.0
PYH2_k127_737620_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000113 175.0
PYH2_k127_737620_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000004308 104.0
PYH2_k127_7434497_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 4.443e-197 622.0
PYH2_k127_7434497_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000108 65.0
PYH2_k127_7488737_0 Phytoene dehydrogenase K15745 - 1.3.99.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 409.0
PYH2_k127_7495661_0 A-macroglobulin receptor - - - 0.0 1360.0
PYH2_k127_7495661_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003595 272.0
PYH2_k127_7502340_0 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 528.0
PYH2_k127_7502340_1 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 461.0
PYH2_k127_7502340_11 - - - - 0.000000001192 67.0
PYH2_k127_7502340_12 Tetratricopeptide repeat - - - 0.000000568 62.0
PYH2_k127_7502340_2 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 319.0
PYH2_k127_7502340_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002439 269.0
PYH2_k127_7502340_4 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005188 242.0
PYH2_k127_7502340_5 Phage shock protein A K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
PYH2_k127_7502340_6 - - - - 0.000000000000000000000000000000000000000000000000000004299 204.0
PYH2_k127_7502340_8 - - - - 0.00000000000000000000000001092 119.0
PYH2_k127_7502340_9 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000001307 99.0
PYH2_k127_7508099_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 434.0
PYH2_k127_7508099_1 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 327.0
PYH2_k127_7508099_2 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000002157 198.0
PYH2_k127_7508099_3 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000002259 154.0
PYH2_k127_7508099_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000127 156.0
PYH2_k127_7508099_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000004505 157.0
PYH2_k127_7508099_6 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000002249 72.0
PYH2_k127_7508099_7 YoaP-like - - - 0.000000000004197 76.0
PYH2_k127_7517442_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.469e-296 927.0
PYH2_k127_7517442_1 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 357.0
PYH2_k127_7517442_2 - - - - 0.000001232 53.0
PYH2_k127_7544834_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 500.0
PYH2_k127_7544834_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 423.0
PYH2_k127_7544834_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 331.0
PYH2_k127_7544834_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 306.0
PYH2_k127_7544834_4 enoyl-CoA hydratase - - - 0.00007814 47.0
PYH2_k127_7564857_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 2.451e-206 657.0
PYH2_k127_7565975_0 ABC transporter K10548 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 628.0
PYH2_k127_7565975_1 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 526.0
PYH2_k127_7565975_2 Periplasmic binding protein domain K10546 - - 0.00000000000000000000000000001205 119.0
PYH2_k127_7579111_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 489.0
PYH2_k127_7579111_1 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000004241 196.0
PYH2_k127_7579111_2 - - - - 0.00000000000000000000000000000000000000001194 168.0
PYH2_k127_7579111_3 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.0000004084 53.0
PYH2_k127_7605991_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.834e-204 645.0
PYH2_k127_7605991_1 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 431.0
PYH2_k127_7605991_2 thioesterase K07107 - - 0.000000000000000000007847 97.0
PYH2_k127_7637990_0 Endopeptidase La K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 543.0
PYH2_k127_767397_0 PFAM Glycosyl transferase, group 1 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 394.0
PYH2_k127_767397_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 310.0
PYH2_k127_767397_2 Cephalosporin hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 263.0
PYH2_k127_767397_3 Glycosyltransferase like family 2 K07011,K20444 - - 0.000000000000000000000000000000000001224 162.0
PYH2_k127_767397_4 PFAM ABC transporter related K09691 - - 0.00000418 49.0
PYH2_k127_7688968_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.951e-206 656.0
PYH2_k127_7688968_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 467.0
PYH2_k127_7688968_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 273.0
PYH2_k127_7688968_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
PYH2_k127_7688968_4 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000002018 235.0
PYH2_k127_7688968_5 - - - - 0.000000000000000000000000000004513 126.0
PYH2_k127_7688968_6 - - - - 0.0000000000000000000006186 96.0
PYH2_k127_7688968_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000001583 94.0
PYH2_k127_76909_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 4.725e-226 712.0
PYH2_k127_7691512_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 5.432e-209 663.0
PYH2_k127_7691512_1 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 517.0
PYH2_k127_7691512_10 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000007205 141.0
PYH2_k127_7691512_11 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000001343 119.0
PYH2_k127_7691512_12 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000003235 87.0
PYH2_k127_7691512_14 TIGRFAM cytochrome C family protein - - - 0.00003299 53.0
PYH2_k127_7691512_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 342.0
PYH2_k127_7691512_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 300.0
PYH2_k127_7691512_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009858 276.0
PYH2_k127_7691512_5 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 266.0
PYH2_k127_7691512_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000001368 220.0
PYH2_k127_7691512_7 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000002525 171.0
PYH2_k127_7691512_8 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000000000000009613 154.0
PYH2_k127_7691512_9 endonuclease - - - 0.00000000000000000000000000000004593 131.0
PYH2_k127_7715436_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 312.0
PYH2_k127_7715436_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000003676 258.0
PYH2_k127_7715436_2 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003854 241.0
PYH2_k127_7715436_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
PYH2_k127_7715436_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000005743 214.0
PYH2_k127_7715436_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000001066 161.0
PYH2_k127_7715436_6 Belongs to the UPF0312 family - - - 0.000000000000000000000000001323 119.0
PYH2_k127_7741354_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 8.236e-268 836.0
PYH2_k127_7741354_1 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 486.0
PYH2_k127_7741354_2 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 388.0
PYH2_k127_7741354_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000004891 150.0
PYH2_k127_7796391_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 427.0
PYH2_k127_7796391_1 Stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 370.0
PYH2_k127_7796391_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000002184 213.0
PYH2_k127_7796391_3 Smr domain - - - 0.00000000000000000000000000000004806 127.0
PYH2_k127_7796391_4 Histidine kinase A domain protein - - - 0.00000000000000003031 85.0
PYH2_k127_7801871_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 455.0
PYH2_k127_7801871_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000002131 194.0
PYH2_k127_7801871_2 - - - - 0.00000000000000000000001367 115.0
PYH2_k127_7829998_0 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000001489 166.0
PYH2_k127_7829998_1 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000003534 126.0
PYH2_k127_7829998_2 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.00000000000000003757 87.0
PYH2_k127_7829998_3 - - - - 0.00000000000004385 73.0
PYH2_k127_7839689_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000001482 138.0
PYH2_k127_7839689_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0000005509 60.0
PYH2_k127_7903395_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 521.0
PYH2_k127_7903395_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007642 280.0
PYH2_k127_7903395_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000005646 64.0
PYH2_k127_792714_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.013e-212 672.0
PYH2_k127_792714_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 417.0
PYH2_k127_7951825_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 314.0
PYH2_k127_7951825_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000004202 174.0
PYH2_k127_7951825_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000001 177.0
PYH2_k127_7968867_0 Stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000007159 253.0
PYH2_k127_7968867_1 - - - - 0.0000000000001113 78.0
PYH2_k127_798328_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
PYH2_k127_798328_1 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000001208 248.0
PYH2_k127_798328_2 tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000116 157.0
PYH2_k127_798328_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000008188 138.0
PYH2_k127_803805_0 Tetratricopeptide repeat protein - - - 0.000000000000000000000000000000000000000000000000001595 205.0
PYH2_k127_803805_1 - - - - 0.0000000000000000000000000000000001501 136.0
PYH2_k127_803805_2 COG1388 FOG LysM repeat K19223,K19224,K21471 - - 0.000002461 60.0
PYH2_k127_803805_3 Mut7-C ubiquitin K03154 - - 0.00003797 55.0
PYH2_k127_8038513_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 430.0
PYH2_k127_8038513_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000006593 111.0
PYH2_k127_8072365_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.017e-196 625.0
PYH2_k127_8072365_1 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000001393 228.0
PYH2_k127_8072365_2 NurA - - - 0.000000000000000000000000000000000000000005399 168.0
PYH2_k127_8072365_3 belongs to the nudix hydrolase family K03574 - 3.6.1.55 0.0000001122 54.0
PYH2_k127_8122696_0 Domain of unknown function (DUF348) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 310.0
PYH2_k127_8122696_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 294.0
PYH2_k127_8122696_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000223 179.0
PYH2_k127_8122696_3 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000005575 145.0
PYH2_k127_8122696_4 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000008108 121.0
PYH2_k127_8122696_5 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.0000003881 62.0
PYH2_k127_833927_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 481.0
PYH2_k127_833927_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000003535 57.0
PYH2_k127_8384258_0 PhoQ Sensor - - - 3.723e-303 977.0
PYH2_k127_8384258_1 Response regulator receiver K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005032 262.0
PYH2_k127_8384258_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000001494 203.0
PYH2_k127_8384258_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000001224 171.0
PYH2_k127_8384258_4 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.00000000000000000000000000000000000000000003773 168.0
PYH2_k127_8384258_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000001051 163.0
PYH2_k127_8384258_6 - - - - 0.0000000000000000009024 91.0
PYH2_k127_8408005_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1784.0
PYH2_k127_8408005_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.684e-238 760.0
PYH2_k127_8408005_2 Regulatory protein, FmdB family - - - 0.000000000000000002043 87.0
PYH2_k127_8408005_3 Heat shock protein DnaJ domain protein - - - 0.000000002686 68.0
PYH2_k127_8408005_4 - - - - 0.0003059 46.0
PYH2_k127_8434633_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 584.0
PYH2_k127_8434633_1 amino acid transport K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 406.0
PYH2_k127_8434633_2 abc transporter atp-binding protein K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 319.0
PYH2_k127_8434633_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 312.0
PYH2_k127_8434633_4 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 228.0
PYH2_k127_8434633_5 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000001069 165.0
PYH2_k127_8434633_6 Ndr family - - - 0.00000000000000000008144 92.0
PYH2_k127_8440957_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 9.561e-273 862.0
PYH2_k127_8440957_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 359.0
PYH2_k127_8440957_10 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000001086 79.0
PYH2_k127_8440957_11 Iron permease FTR1 family K07243 - - 0.000004316 58.0
PYH2_k127_8440957_12 Thioredoxin - - - 0.0001496 44.0
PYH2_k127_8440957_13 Protein of unknown function (DUF1573) - - - 0.0005491 44.0
PYH2_k127_8440957_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
PYH2_k127_8440957_3 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000007017 224.0
PYH2_k127_8440957_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000005875 198.0
PYH2_k127_8440957_5 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000007059 187.0
PYH2_k127_8440957_6 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000001104 145.0
PYH2_k127_8440957_7 Protein of unknown function with PCYCGC motif - - - 0.000000000000000000000000884 108.0
PYH2_k127_8440957_8 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000002129 102.0
PYH2_k127_8440957_9 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000001412 94.0
PYH2_k127_8445423_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.526e-247 787.0
PYH2_k127_8445423_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 4.315e-212 675.0
PYH2_k127_8445423_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
PYH2_k127_8445423_3 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 282.0
PYH2_k127_8445423_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000007493 194.0
PYH2_k127_8445423_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000001761 154.0
PYH2_k127_8445423_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000008868 134.0
PYH2_k127_8451237_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 5.38e-202 640.0
PYH2_k127_8451237_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 598.0
PYH2_k127_8451237_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
PYH2_k127_8451237_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
PYH2_k127_8451237_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000001788 124.0
PYH2_k127_8451656_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 491.0
PYH2_k127_8451656_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 402.0
PYH2_k127_8451656_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000003627 171.0
PYH2_k127_8451656_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000004661 149.0
PYH2_k127_8451656_4 protein localization to endoplasmic reticulum - - - 0.000000000000000218 90.0
PYH2_k127_8452385_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
PYH2_k127_8452385_1 nodulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009047 274.0
PYH2_k127_8452385_2 Phospholipase/Carboxylesterase - - - 0.0000000000000000000000000000002862 128.0
PYH2_k127_8452385_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000002043 95.0
PYH2_k127_8452385_4 ABC-2 family transporter protein K01992 - - 0.0000000000000001058 91.0
PYH2_k127_8452385_5 - - - - 0.000000000000006163 78.0
PYH2_k127_8467501_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 603.0
PYH2_k127_8467501_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 590.0
PYH2_k127_8467501_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 397.0
PYH2_k127_8467501_3 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001711 279.0
PYH2_k127_8467501_4 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006231 253.0
PYH2_k127_8467501_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000001314 192.0
PYH2_k127_8467501_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000001279 164.0
PYH2_k127_8467501_7 chromate transporter K07240 - - 0.000000000000000000000000000000000002319 144.0
PYH2_k127_8467501_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000002033 100.0
PYH2_k127_8467501_9 - - - - 0.00002072 49.0
PYH2_k127_8488401_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.418e-219 703.0
PYH2_k127_8488401_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 528.0
PYH2_k127_8488401_10 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001359 232.0
PYH2_k127_8488401_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000009946 162.0
PYH2_k127_8488401_12 YacP-like NYN domain K06962 - - 0.0000000000000000000000000007807 118.0
PYH2_k127_8488401_2 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 441.0
PYH2_k127_8488401_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 456.0
PYH2_k127_8488401_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 430.0
PYH2_k127_8488401_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 360.0
PYH2_k127_8488401_6 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 312.0
PYH2_k127_8488401_7 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000001203 252.0
PYH2_k127_8488401_8 PFAM DoxX family protein K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000006069 243.0
PYH2_k127_8488401_9 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000007348 231.0
PYH2_k127_8499577_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 401.0
PYH2_k127_8499577_1 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000000000000000000000000000000001294 202.0
PYH2_k127_8499577_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000001207 169.0
PYH2_k127_8499577_3 Biotin-lipoyl like K01993 - - 0.000000007683 66.0
PYH2_k127_8504011_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.414e-306 947.0
PYH2_k127_8504011_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 423.0
PYH2_k127_8508614_0 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 499.0
PYH2_k127_8508614_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005691 286.0
PYH2_k127_8508614_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000003992 126.0
PYH2_k127_8508614_3 DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000000000000000003564 127.0
PYH2_k127_8508614_4 PFAM NAD dependent epimerase dehydratase family - - - 0.0000168 47.0
PYH2_k127_8521197_0 PFAM glycosyl transferase family 39 - - - 0.0000000000000003703 89.0
PYH2_k127_8521197_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000008328 85.0
PYH2_k127_8521197_2 Bacterial membrane protein, YfhO - - - 0.0006266 53.0
PYH2_k127_8523026_0 Polysaccharide biosynthesis protein K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 497.0
PYH2_k127_8523026_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000006835 153.0
PYH2_k127_8523026_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000006634 109.0
PYH2_k127_8523026_3 Transposase DDE domain K07492 - - 0.00000000000000000002333 96.0
PYH2_k127_8523026_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000006125 60.0
PYH2_k127_8523026_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000001167 66.0
PYH2_k127_8566288_0 ABC transporter, transmembrane region K06147 - - 1.729e-279 871.0
PYH2_k127_8566288_1 ABC transporter K06147 - - 1.26e-271 854.0
PYH2_k127_8566288_2 Molybdopterin oxidoreductase - - - 1.439e-247 779.0
PYH2_k127_8566288_3 Patatin-like phospholipase K06900 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 392.0
PYH2_k127_8566288_4 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000002133 170.0
PYH2_k127_8566288_5 PFAM MarR family - - - 0.0000000000000000000000000000000000000000007241 161.0
PYH2_k127_8566288_6 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000005719 114.0
PYH2_k127_8566288_7 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.000000000231 64.0
PYH2_k127_8566288_8 COG2801 Transposase and inactivated derivatives K07497 - - 0.0001603 46.0
PYH2_k127_8567650_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000007517 121.0
PYH2_k127_8597691_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 453.0
PYH2_k127_8597691_1 Protein of unknown function (DUF2652) - - - 0.000000000000000000000003256 107.0
PYH2_k127_8604232_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 336.0
PYH2_k127_8604232_1 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
PYH2_k127_86130_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1412.0
PYH2_k127_86130_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 493.0
PYH2_k127_86130_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 395.0
PYH2_k127_86130_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000002187 139.0
PYH2_k127_86130_4 Amidohydrolase family - - - 0.000000000006479 79.0
PYH2_k127_8634457_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 299.0
PYH2_k127_8634457_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001055 278.0
PYH2_k127_8634457_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
PYH2_k127_8634457_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000186 215.0
PYH2_k127_8665509_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 434.0
PYH2_k127_8665509_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000007932 238.0
PYH2_k127_8665509_2 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
PYH2_k127_8665509_3 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000001132 179.0
PYH2_k127_8665509_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000001261 115.0
PYH2_k127_8677822_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 385.0
PYH2_k127_8677822_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000001018 241.0
PYH2_k127_8679721_0 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 372.0
PYH2_k127_8679721_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 358.0
PYH2_k127_8679721_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004523 265.0
PYH2_k127_8679721_3 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000006514 191.0
PYH2_k127_8679721_5 6-phospho-beta-galactosidase activity - - - 0.00000000000000001754 97.0
PYH2_k127_8685427_0 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 463.0
PYH2_k127_8685427_1 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000006486 222.0
PYH2_k127_8685427_2 Carboxypeptidase - - - 0.0000000000000000000000000000000000008619 149.0
PYH2_k127_8693508_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009754 284.0
PYH2_k127_8693508_1 - - - - 0.00000000000001276 76.0
PYH2_k127_8693508_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000007144 72.0
PYH2_k127_8693508_3 Protein of unknown function (DUF2283) - - - 0.00000006117 57.0
PYH2_k127_8705456_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 447.0
PYH2_k127_8705456_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 402.0
PYH2_k127_8718672_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 3.83e-227 721.0
PYH2_k127_8718672_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 302.0
PYH2_k127_8718672_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000002521 213.0
PYH2_k127_8718672_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000002082 202.0
PYH2_k127_8718672_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000002578 204.0
PYH2_k127_8718672_5 serine-type endopeptidase activity K04771,K08372 - 3.4.21.107 0.0000004369 60.0
PYH2_k127_8731443_0 - - - - 0.000003338 58.0
PYH2_k127_8737339_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 642.0
PYH2_k127_8737339_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 505.0
PYH2_k127_8737339_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 436.0
PYH2_k127_8737339_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 436.0
PYH2_k127_8737339_4 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000008864 135.0
PYH2_k127_8737339_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000001655 113.0
PYH2_k127_8737339_6 Psort location CytoplasmicMembrane, score K00368 - 1.7.2.1 0.00000000000000007088 89.0
PYH2_k127_8745431_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 546.0
PYH2_k127_8745431_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 436.0
PYH2_k127_8745431_2 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 386.0
PYH2_k127_8745431_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 330.0
PYH2_k127_8745431_4 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000001126 129.0
PYH2_k127_8745431_6 COG0489 ATPases involved in chromosome partitioning - - - 0.000000000000008024 80.0
PYH2_k127_8745431_7 Kelch motif - - - 0.0000000006682 67.0
PYH2_k127_87822_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 419.0
PYH2_k127_87822_1 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000001089 240.0
PYH2_k127_87822_10 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000005129 132.0
PYH2_k127_87822_11 response regulator - - - 0.0000000000000000000000001412 120.0
PYH2_k127_87822_12 subunit of a heme lyase K02200 - - 0.000000000000000000000005581 109.0
PYH2_k127_87822_13 - - - - 0.000000000000002268 81.0
PYH2_k127_87822_14 zinc-ribbon domain - - - 0.000000001047 66.0
PYH2_k127_87822_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000003369 251.0
PYH2_k127_87822_3 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000001083 217.0
PYH2_k127_87822_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000001464 204.0
PYH2_k127_87822_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000007457 192.0
PYH2_k127_87822_6 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000007973 160.0
PYH2_k127_87822_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000003659 152.0
PYH2_k127_87822_8 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000004372 141.0
PYH2_k127_87822_9 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000002383 133.0
PYH2_k127_8827546_0 P-type ATPase K17686 - 3.6.3.54 9.352e-233 743.0
PYH2_k127_8827546_1 Metal-sensitive transcriptional repressor K21600 - - 0.000001438 50.0
PYH2_k127_8846312_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 407.0
PYH2_k127_8846312_1 PFAM peptidase M29, aminopeptidase II K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 396.0
PYH2_k127_8846312_10 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.0000000000000000000000000000001673 129.0
PYH2_k127_8846312_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000003219 139.0
PYH2_k127_8846312_12 metal cluster binding K06940,K18475 - - 0.00000000000000000000000004658 115.0
PYH2_k127_8846312_2 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 366.0
PYH2_k127_8846312_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 367.0
PYH2_k127_8846312_4 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 358.0
PYH2_k127_8846312_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 329.0
PYH2_k127_8846312_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003051 231.0
PYH2_k127_8846312_7 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000004674 183.0
PYH2_k127_8846312_8 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000007596 166.0
PYH2_k127_8846312_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000307 133.0
PYH2_k127_8860654_0 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 3.738e-244 764.0
PYH2_k127_8860654_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 353.0
PYH2_k127_8860654_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 286.0
PYH2_k127_8860654_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008179 241.0
PYH2_k127_8860654_4 4Fe-4S dicluster domain K12143 - - 0.00000000000000000000000000000000000000000000000000000000000001114 220.0
PYH2_k127_8860654_5 2 iron, 2 sulfur cluster binding K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000001355 176.0
PYH2_k127_8860654_6 Hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000000000000000000000000000006957 170.0
PYH2_k127_8860654_7 Formate hydrogenlyase maturation protein HycH K12145,K15834 - - 0.0000000000000000000000000000000002824 135.0
PYH2_k127_8860654_8 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.00000000000000000000000001561 112.0
PYH2_k127_8860859_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 616.0
PYH2_k127_8860859_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 611.0
PYH2_k127_8860859_2 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000009581 228.0
PYH2_k127_8860859_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000001459 177.0
PYH2_k127_8860859_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000002414 178.0
PYH2_k127_8860859_5 - - - - 0.00000000000000005312 83.0
PYH2_k127_8860859_6 cell adhesion involved in biofilm formation - - - 0.0000000000000002991 83.0
PYH2_k127_8860859_7 Protease prsW family - - - 0.00000000004285 74.0
PYH2_k127_8860859_8 PhoQ Sensor - - - 0.000002838 61.0
PYH2_k127_8912342_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1135.0
PYH2_k127_8912342_1 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000007798 245.0
PYH2_k127_8912342_2 ferric iron binding K02217,K22336 GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1,1.16.3.2 0.00000000000000000000000000000000000000000000000000000001067 203.0
PYH2_k127_8912342_3 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000007267 187.0
PYH2_k127_8912342_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000499 172.0
PYH2_k127_8912342_5 Cupin domain - - - 0.000000000000000000000000000000000000000003846 161.0
PYH2_k127_8912342_6 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000003092 159.0
PYH2_k127_8912342_7 GrpB protein - - - 0.0000000000000000000000001447 112.0
PYH2_k127_8912342_8 - - - - 0.000002538 61.0
PYH2_k127_8924408_0 Mannosyl oligosaccharide glucosidase - - - 1.244e-315 980.0
PYH2_k127_8924408_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 395.0
PYH2_k127_8924408_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000003273 265.0
PYH2_k127_8949042_0 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000005429 238.0
PYH2_k127_8949042_1 EamA-like transporter family - - - 0.000000000000000000000000000000000001948 146.0
PYH2_k127_8949042_2 zinc-ribbon family - - - 0.00000000000000000000000001761 116.0
PYH2_k127_8954484_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000001096 195.0
PYH2_k127_8954484_1 DinB superfamily - - - 0.0000000002197 71.0
PYH2_k127_8967862_0 Aminotransferase class-III - - - 4.554e-210 661.0
PYH2_k127_8967862_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000002433 124.0
PYH2_k127_8967862_2 Psort location Cytoplasmic, score - - - 0.00000000000000000001397 110.0
PYH2_k127_8967862_3 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000002405 91.0
PYH2_k127_8967862_4 WD40-like Beta Propeller K03641 - - 0.00000000000005016 88.0
PYH2_k127_8967862_5 Esterase, phb depolymerase family - - - 0.0000005841 57.0
PYH2_k127_8967862_6 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0006811 46.0
PYH2_k127_9008045_0 - - - - 0.000000000000000000000002119 116.0
PYH2_k127_9029131_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000001915 170.0
PYH2_k127_9029131_1 Domain of unknown function DUF11 - - - 0.00001442 55.0
PYH2_k127_9029131_2 domain protein K14194 - - 0.0002475 49.0
PYH2_k127_9138737_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 541.0
PYH2_k127_9138737_1 PFAM NAD dependent epimerase dehydratase family K01784,K08678 - 4.1.1.35,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 388.0
PYH2_k127_9138737_2 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 374.0
PYH2_k127_9138737_3 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000002182 222.0
PYH2_k127_9138737_4 chromosome segregation K03497 - - 0.000000000000000000000000000000000002105 147.0
PYH2_k127_9138737_5 Transglycosylase SLT domain - - - 0.00000000000000000000986 106.0
PYH2_k127_9154640_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.028e-251 788.0
PYH2_k127_9154640_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 351.0
PYH2_k127_9154640_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000001102 238.0
PYH2_k127_9154640_3 Allene oxide cyclase - - - 0.0000000000000000000000000000000000000000000488 164.0
PYH2_k127_9154640_4 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000542 168.0
PYH2_k127_9154640_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000004478 137.0
PYH2_k127_9191985_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1124.0
PYH2_k127_9191985_1 Belongs to the ClpA ClpB family K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1105.0
PYH2_k127_9191985_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000005998 102.0
PYH2_k127_9283128_0 Voltage gated chloride channel - - - 1.853e-245 771.0
PYH2_k127_9283128_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 419.0
PYH2_k127_9283128_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 389.0
PYH2_k127_9283128_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000002178 162.0
PYH2_k127_9283128_4 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000004758 126.0
PYH2_k127_9283128_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000176 69.0
PYH2_k127_9286443_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 562.0
PYH2_k127_9286443_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 464.0
PYH2_k127_9286443_2 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003728 277.0
PYH2_k127_9286443_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000001192 57.0
PYH2_k127_9306153_0 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 402.0
PYH2_k127_9306153_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 376.0
PYH2_k127_9306153_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
PYH2_k127_9306153_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000003716 151.0
PYH2_k127_936895_0 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 298.0
PYH2_k127_936895_1 PFAM extracellular solute-binding protein family 1 - - - 0.00000000000000000000000000000000000000000000000000000000212 209.0
PYH2_k127_936895_2 - - - - 0.000000000000000000000000000000000000000001502 164.0
PYH2_k127_942836_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000001036 138.0
PYH2_k127_942836_1 S-layer homology domain - - - 0.0003677 49.0
PYH2_k127_958187_0 succinate dehydrogenase K00244 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 523.0
PYH2_k127_958187_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 480.0
PYH2_k127_958187_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 329.0
PYH2_k127_958187_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 295.0
PYH2_k127_958187_4 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000003537 227.0
PYH2_k127_958187_5 2-dehydro-3-deoxy-phosphogluconate aldolase activity K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000001611 198.0
PYH2_k127_958187_6 mannose-6-phosphate isomerase - - - 0.0000000000002325 72.0
PYH2_k127_959085_0 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005737 289.0
PYH2_k127_959085_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 277.0
PYH2_k127_959085_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005208 228.0
PYH2_k127_959085_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000004457 89.0
PYH2_k127_959085_4 PhoQ Sensor - - - 0.00002531 54.0
PYH2_k127_959085_5 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0002065 44.0
PYH2_k127_959267_0 Histidine kinase A domain protein - - - 6.359e-197 667.0
PYH2_k127_959267_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 347.0
PYH2_k127_959711_0 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 556.0
PYH2_k127_959711_1 PFAM ROK family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 345.0
PYH2_k127_959711_2 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003719 254.0
PYH2_k127_959711_3 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000002757 209.0
PYH2_k127_962742_0 TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 432.0
PYH2_k127_962742_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 399.0
PYH2_k127_962742_2 Flavin-binding monooxygenase-like K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 364.0
PYH2_k127_962742_3 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001915 246.0
PYH2_k127_962742_4 TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000007261 190.0
PYH2_k127_962742_5 Phenylacetate-CoA oxygenase K02610 - - 0.0000000000000000000007701 100.0
PYH2_k127_962742_6 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000001398 76.0
PYH2_k127_963208_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 435.0
PYH2_k127_963208_1 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008707 280.0
PYH2_k127_963208_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000002632 191.0
PYH2_k127_972351_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 573.0
PYH2_k127_972351_1 DNA topological change - - - 0.0000000001875 64.0
PYH2_k127_972351_2 acetylesterase activity K15923 - 3.2.1.51 0.0002138 50.0
PYH2_k127_983069_0 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 535.0
PYH2_k127_983069_1 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000004189 134.0
PYH2_k127_984490_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 8.434e-240 748.0
PYH2_k127_984490_1 SMART Elongator protein 3 MiaB NifB - - - 1.14e-212 670.0
PYH2_k127_984490_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 314.0
PYH2_k127_984490_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000004218 213.0
PYH2_k127_984490_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000004026 192.0
PYH2_k127_984490_5 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000003818 194.0
PYH2_k127_984490_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000001732 163.0
PYH2_k127_984490_7 polysaccharide biosynthetic process - - - 0.00001542 54.0
PYH2_k127_985194_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 302.0
PYH2_k127_985194_1 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000003252 201.0
PYH2_k127_985194_2 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000009452 194.0
PYH2_k127_985194_3 transcriptional regulator - - - 0.0000000000000000000000000498 112.0
PYH2_k127_985194_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000003514 81.0
PYH2_k127_986534_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 4.594e-197 636.0
PYH2_k127_986534_1 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 500.0
PYH2_k127_986534_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 460.0
PYH2_k127_986534_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 422.0
PYH2_k127_986534_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
PYH2_k127_986534_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000811 166.0
PYH2_k127_987715_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.112e-298 939.0
PYH2_k127_987715_1 Selenocysteine-specific translation elongation factor K03833 - - 5.695e-199 639.0
PYH2_k127_987715_10 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 350.0
PYH2_k127_987715_11 Transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 361.0
PYH2_k127_987715_12 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 308.0
PYH2_k127_987715_13 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 295.0
PYH2_k127_987715_14 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000005649 247.0
PYH2_k127_987715_15 SPTR D1CI93 Phophonate C-P lyase system transcriptional regulator PhnF, GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000001751 222.0
PYH2_k127_987715_16 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000002803 182.0
PYH2_k127_987715_17 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000131 164.0
PYH2_k127_987715_18 peptidase - - - 0.0000000000000000000000000000000000000001508 166.0
PYH2_k127_987715_19 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000007639 147.0
PYH2_k127_987715_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 572.0
PYH2_k127_987715_20 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000006552 130.0
PYH2_k127_987715_21 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000003245 114.0
PYH2_k127_987715_22 response to heat K03668,K09914 - - 0.0000000000000000001518 99.0
PYH2_k127_987715_23 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000004607 91.0
PYH2_k127_987715_24 cheY-homologous receiver domain - - - 0.000000000000000001722 90.0
PYH2_k127_987715_25 Chitinase class I K03791 - - 0.00000000000000001149 92.0
PYH2_k127_987715_26 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.000001794 61.0
PYH2_k127_987715_27 glycerophosphodiester transmembrane transport K17246 - - 0.0001157 47.0
PYH2_k127_987715_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 558.0
PYH2_k127_987715_4 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 479.0
PYH2_k127_987715_5 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 509.0
PYH2_k127_987715_6 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 426.0
PYH2_k127_987715_7 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 393.0
PYH2_k127_987715_8 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 372.0
PYH2_k127_987715_9 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 358.0