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Overview

ID MAG03178
Name PYH2_bin.18
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus 2-02-FULL-66-14
Species
Assembly information
Completeness (%) 84.39
Contamination (%) 1.94
GC content (%) 68.0
N50 (bp) 5,803
Genome size (bp) 2,693,583

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3006

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1005219_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 448.0
PYH2_k127_1005219_2 Cytochrome c - - - 0.00000000279 61.0
PYH2_k127_1005219_3 FixH family K09926 - - 0.0001746 44.0
PYH2_k127_1005655_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1014.0
PYH2_k127_1005655_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000002257 132.0
PYH2_k127_1007563_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 333.0
PYH2_k127_1007563_1 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
PYH2_k127_1007563_2 GGDEF domain K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000005253 230.0
PYH2_k127_1007563_3 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000003111 134.0
PYH2_k127_1007563_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000000000000000000000001761 132.0
PYH2_k127_1007563_5 Cytochrome c554 and c-prime - - - 0.0000000000001079 76.0
PYH2_k127_1007563_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000101 65.0
PYH2_k127_1024208_0 indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 2.083e-255 799.0
PYH2_k127_1024208_1 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.00000000000000000003248 90.0
PYH2_k127_1026620_0 Diguanylate cyclase - - - 4.685e-295 936.0
PYH2_k127_1026620_1 elongation factor G K02355 - - 7.14e-294 915.0
PYH2_k127_1026620_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 592.0
PYH2_k127_1026620_3 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 483.0
PYH2_k127_1026620_4 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 339.0
PYH2_k127_1026620_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
PYH2_k127_1026620_6 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.000000000000000000000000000001973 127.0
PYH2_k127_1026620_7 hydrolase activity, acting on ester bonds - - - 0.000000001543 61.0
PYH2_k127_1033892_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 451.0
PYH2_k127_1033892_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000003196 57.0
PYH2_k127_105684_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 5.068e-270 847.0
PYH2_k127_105684_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.358e-233 739.0
PYH2_k127_105684_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.859e-232 736.0
PYH2_k127_105684_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 326.0
PYH2_k127_105684_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 310.0
PYH2_k127_105684_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 311.0
PYH2_k127_105684_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001307 247.0
PYH2_k127_105684_7 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000000001957 130.0
PYH2_k127_1065704_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 516.0
PYH2_k127_1065704_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 400.0
PYH2_k127_1065704_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 355.0
PYH2_k127_1065704_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000007862 181.0
PYH2_k127_1065704_4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000002095 156.0
PYH2_k127_1068557_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.336e-195 620.0
PYH2_k127_1068557_1 - - - - 0.0000000000008216 73.0
PYH2_k127_1068557_2 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000001094 68.0
PYH2_k127_1089258_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 536.0
PYH2_k127_1089258_1 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004691 231.0
PYH2_k127_1089258_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000143 233.0
PYH2_k127_1089258_3 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000001403 134.0
PYH2_k127_1089258_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000008343 124.0
PYH2_k127_1100053_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 452.0
PYH2_k127_1100053_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 343.0
PYH2_k127_1100053_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000005799 195.0
PYH2_k127_1100053_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.000000000000000000000000006383 113.0
PYH2_k127_1100502_0 pilus assembly protein PilZ K02676 - - 0.00000000000000000000000000000000000000002201 161.0
PYH2_k127_1100502_1 ankyrin repeat K06867 - - 0.0000000000000000000000000000000000005997 148.0
PYH2_k127_1100502_2 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000342 139.0
PYH2_k127_1100502_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000003394 138.0
PYH2_k127_1137848_0 Neisseria PilC beta-propeller domain K02674 - - 2.836e-210 704.0
PYH2_k127_1137848_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 459.0
PYH2_k127_1137848_10 Pilus assembly protein PilX - - - 0.0000000000000000000000000000405 124.0
PYH2_k127_1137848_11 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000001106 112.0
PYH2_k127_1137848_12 Type II transport protein GspH K08084 - - 0.000000000000000000000001058 111.0
PYH2_k127_1137848_13 Thioesterase superfamily - - - 0.000000001039 66.0
PYH2_k127_1137848_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 400.0
PYH2_k127_1137848_3 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 310.0
PYH2_k127_1137848_4 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 315.0
PYH2_k127_1137848_5 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 269.0
PYH2_k127_1137848_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000003392 252.0
PYH2_k127_1137848_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000005111 241.0
PYH2_k127_1137848_8 type 4 fimbrial biogenesis K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000002871 238.0
PYH2_k127_1137848_9 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000008972 157.0
PYH2_k127_116286_0 - - - - 0.0 1306.0
PYH2_k127_116286_1 hydrolase activity, acting on ester bonds K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 465.0
PYH2_k127_116286_10 cytochrome c5 - - - 0.00000000000000000000000000000000000000000001401 171.0
PYH2_k127_116286_11 Rubrerythrin - - - 0.0001373 48.0
PYH2_k127_116286_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 370.0
PYH2_k127_116286_3 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 348.0
PYH2_k127_116286_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 338.0
PYH2_k127_116286_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 292.0
PYH2_k127_116286_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005097 292.0
PYH2_k127_116286_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000719 224.0
PYH2_k127_116286_8 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000002138 181.0
PYH2_k127_116286_9 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000002373 181.0
PYH2_k127_1171990_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 8.768e-296 925.0
PYH2_k127_1171990_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 482.0
PYH2_k127_1171990_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 379.0
PYH2_k127_1171990_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 392.0
PYH2_k127_1171990_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
PYH2_k127_1171990_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 351.0
PYH2_k127_1171990_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000202 211.0
PYH2_k127_1171990_7 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000004671 198.0
PYH2_k127_1175666_0 COG4618 ABC-type protease lipase transport system, ATPase and permease components K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000211 251.0
PYH2_k127_1175666_1 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000001417 205.0
PYH2_k127_1175666_2 Response regulator, receiver - - - 0.00000000000000000000000000000000000001082 153.0
PYH2_k127_1195447_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1335.0
PYH2_k127_1195447_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 550.0
PYH2_k127_1195447_2 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000002936 204.0
PYH2_k127_1195447_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000003308 144.0
PYH2_k127_1195447_4 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000001891 114.0
PYH2_k127_1195447_5 Universal stress protein - - - 0.0000000000000000000001261 102.0
PYH2_k127_1195447_6 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001363 105.0
PYH2_k127_1195447_7 Biotin-requiring enzyme - - - 0.0000000000000007623 86.0
PYH2_k127_1202356_0 Sulfatase K01130,K01138 - 3.1.6.1 0.0 1379.0
PYH2_k127_1202356_1 Sulfatase - - - 2.156e-222 698.0
PYH2_k127_1202356_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 1.352e-215 680.0
PYH2_k127_1202356_3 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 426.0
PYH2_k127_1202356_4 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 382.0
PYH2_k127_1202356_5 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
PYH2_k127_1202356_6 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000001174 237.0
PYH2_k127_1202356_7 Transcriptional regulator K04761 - - 0.000000000002084 67.0
PYH2_k127_1209546_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.032e-283 886.0
PYH2_k127_1209546_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.32e-229 717.0
PYH2_k127_1209546_10 ABC transporter transmembrane region K11004 - - 0.0000000009533 63.0
PYH2_k127_1209546_11 Histidine kinase K14986 - 2.7.13.3 0.0000004876 61.0
PYH2_k127_1209546_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 559.0
PYH2_k127_1209546_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 556.0
PYH2_k127_1209546_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 434.0
PYH2_k127_1209546_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 420.0
PYH2_k127_1209546_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 374.0
PYH2_k127_1209546_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 331.0
PYH2_k127_1209546_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
PYH2_k127_1209546_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000009562 102.0
PYH2_k127_1227013_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 574.0
PYH2_k127_1227013_1 - - - - 0.000000000000000000000000000002733 130.0
PYH2_k127_1239126_0 GTP-binding protein TypA K06207 - - 4.418e-304 941.0
PYH2_k127_1239126_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 535.0
PYH2_k127_1239126_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 313.0
PYH2_k127_1249577_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 372.0
PYH2_k127_1249577_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
PYH2_k127_1286255_0 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 434.0
PYH2_k127_1286255_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 393.0
PYH2_k127_1286255_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 377.0
PYH2_k127_1286255_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
PYH2_k127_1286255_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001381 269.0
PYH2_k127_1286255_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000007735 72.0
PYH2_k127_1342184_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 601.0
PYH2_k127_1342184_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 516.0
PYH2_k127_1342184_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 471.0
PYH2_k127_1342184_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 432.0
PYH2_k127_1342184_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 360.0
PYH2_k127_1342184_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 352.0
PYH2_k127_1342184_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 353.0
PYH2_k127_1342184_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 323.0
PYH2_k127_1342184_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000002033 257.0
PYH2_k127_1342184_9 Acyl-CoA dehydrogenase, middle domain - - - 0.00000002837 57.0
PYH2_k127_1358983_0 BT1 family - - - 2.833e-231 729.0
PYH2_k127_1358983_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 359.0
PYH2_k127_1358983_2 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000009208 157.0
PYH2_k127_1358983_3 - - - - 0.000000000000000000001012 99.0
PYH2_k127_1358983_4 - - - - 0.0000000107 62.0
PYH2_k127_1367583_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 398.0
PYH2_k127_1367583_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 324.0
PYH2_k127_1367583_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 281.0
PYH2_k127_1367583_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000008496 218.0
PYH2_k127_1372207_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 582.0
PYH2_k127_1372207_1 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 501.0
PYH2_k127_1372207_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 429.0
PYH2_k127_1387300_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1493.0
PYH2_k127_1387300_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000007312 188.0
PYH2_k127_1387300_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000004064 146.0
PYH2_k127_1424198_0 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 325.0
PYH2_k127_1424198_1 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
PYH2_k127_1424198_2 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003556 276.0
PYH2_k127_1424198_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000005572 147.0
PYH2_k127_1435771_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 514.0
PYH2_k127_1435771_1 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 466.0
PYH2_k127_1435771_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000006996 174.0
PYH2_k127_1452786_0 Domain of unknown function (DUF3394) - - - 7.897e-304 944.0
PYH2_k127_1452786_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 6.662e-265 829.0
PYH2_k127_1452786_10 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000002655 188.0
PYH2_k127_1452786_11 SAF K16845 - 4.4.1.24 0.00000000000000000000000000000000000000001447 154.0
PYH2_k127_1452786_12 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000001161 141.0
PYH2_k127_1452786_13 Pfam Sodium hydrogen exchanger - - - 0.000000000000000000000008615 115.0
PYH2_k127_1452786_2 D-galactarate dehydratase K16846,K16850 - 4.2.1.7,4.4.1.24 6.077e-213 670.0
PYH2_k127_1452786_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 478.0
PYH2_k127_1452786_4 Tartrate K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 450.0
PYH2_k127_1452786_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 383.0
PYH2_k127_1452786_6 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 365.0
PYH2_k127_1452786_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 363.0
PYH2_k127_1452786_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 337.0
PYH2_k127_1452786_9 Fumarate K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 323.0
PYH2_k127_1494996_0 Cytochrome b(N-terminal)/b6/petB - - - 3.05e-241 773.0
PYH2_k127_1494996_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 396.0
PYH2_k127_1494996_2 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000007857 242.0
PYH2_k127_1494996_3 - - - - 0.0000000000000000000000000000000002311 145.0
PYH2_k127_1494996_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0006879 45.0
PYH2_k127_1503175_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 581.0
PYH2_k127_1503175_1 LexA DNA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002754 262.0
PYH2_k127_1503175_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005809 263.0
PYH2_k127_1503175_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004356 268.0
PYH2_k127_1503175_4 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
PYH2_k127_1503175_5 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000004025 197.0
PYH2_k127_1503175_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000003844 129.0
PYH2_k127_1504656_0 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
PYH2_k127_1504656_1 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008923 246.0
PYH2_k127_1504656_2 Histidine kinase K10715 - 2.7.13.3 0.0000000000000000000000000000000000000001053 160.0
PYH2_k127_1504656_3 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000006044 141.0
PYH2_k127_1505514_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1352.0
PYH2_k127_1505514_1 Molecular chaperone. Has ATPase activity K04079 - - 1.926e-287 894.0
PYH2_k127_1505514_10 response to cobalt ion - - - 0.0000000000000000000000000000000000000000000002585 174.0
PYH2_k127_1505514_11 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000000000000000000000000000005915 170.0
PYH2_k127_1505514_12 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000007381 120.0
PYH2_k127_1505514_13 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000008063 117.0
PYH2_k127_1505514_14 - - - - 0.00000000000000000000000003212 109.0
PYH2_k127_1505514_15 Transglycosylase associated protein - - - 0.0000000009938 63.0
PYH2_k127_1505514_2 Methylmalonyl-CoA mutase K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 6.602e-243 780.0
PYH2_k127_1505514_3 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 609.0
PYH2_k127_1505514_4 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 501.0
PYH2_k127_1505514_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 508.0
PYH2_k127_1505514_6 Trypsin K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 383.0
PYH2_k127_1505514_7 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
PYH2_k127_1505514_8 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000002152 186.0
PYH2_k127_1505514_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006227 180.0
PYH2_k127_151329_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.812e-233 727.0
PYH2_k127_151329_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K18356 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 553.0
PYH2_k127_151329_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 405.0
PYH2_k127_1520457_0 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000003506 111.0
PYH2_k127_1520457_1 Protein of unknown function (DUF2721) - - - 0.000000000000000000001184 108.0
PYH2_k127_1520457_2 Domain of unknown function (DUF4340) - - - 0.000000000000003077 87.0
PYH2_k127_1521917_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 563.0
PYH2_k127_1533842_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 471.0
PYH2_k127_1533842_1 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000001617 163.0
PYH2_k127_1558273_0 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
PYH2_k127_1558273_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005621 215.0
PYH2_k127_1558273_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000001708 181.0
PYH2_k127_1558273_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000007712 75.0
PYH2_k127_1587703_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 480.0
PYH2_k127_1587703_1 ABC transporter substrate binding protein K01989 - - 0.000000000000004164 80.0
PYH2_k127_1599660_0 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 370.0
PYH2_k127_1599660_1 Abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 368.0
PYH2_k127_1599660_2 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000006822 234.0
PYH2_k127_1600570_0 Participates in both transcription termination and antitermination K02600 - - 7.229e-217 690.0
PYH2_k127_1600570_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 6.027e-205 655.0
PYH2_k127_1600570_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 324.0
PYH2_k127_1600570_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 287.0
PYH2_k127_1600570_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
PYH2_k127_1600570_5 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008061 268.0
PYH2_k127_1600570_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000001453 172.0
PYH2_k127_1600570_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000003267 133.0
PYH2_k127_1600570_8 Belongs to the SUA5 family - - - 0.000000000000007136 74.0
PYH2_k127_1625075_0 Penicillin amidase K01434 - 3.5.1.11 2.638e-203 664.0
PYH2_k127_1625075_1 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 564.0
PYH2_k127_1625075_2 Disulfide bond formation protein DsbB - - - 0.00000000000000000000000000000000000000000002768 170.0
PYH2_k127_1625075_3 acyl-CoA dehydrogenase K09456 - - 0.000000000000003123 76.0
PYH2_k127_1631133_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1.5e-238 757.0
PYH2_k127_1631133_1 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
PYH2_k127_1631133_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000001739 157.0
PYH2_k127_1631133_3 Sulfate permease family - - - 0.0000000003295 63.0
PYH2_k127_1649288_0 PQQ enzyme repeat - - - 4.404e-303 937.0
PYH2_k127_1649288_1 TonB-dependent Receptor Plug Domain K02014 - - 9.356e-216 691.0
PYH2_k127_1649288_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 583.0
PYH2_k127_1649288_3 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 394.0
PYH2_k127_1649288_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
PYH2_k127_1649288_5 PFAM Ankyrin K06867 - - 0.00000000000000000000000000000000000000000000000000003016 195.0
PYH2_k127_1649288_6 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000313 171.0
PYH2_k127_1649288_7 cytochrome - - - 0.000001773 55.0
PYH2_k127_1669006_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 487.0
PYH2_k127_1669006_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000001508 205.0
PYH2_k127_1669006_2 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000001419 78.0
PYH2_k127_1671395_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.023e-255 796.0
PYH2_k127_1671395_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 602.0
PYH2_k127_1671395_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000004045 108.0
PYH2_k127_1671395_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000003117 66.0
PYH2_k127_1674944_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
PYH2_k127_1674944_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 324.0
PYH2_k127_1674944_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000001271 165.0
PYH2_k127_1674944_3 COG3245 Cytochrome c5 - - - 0.000000000000000000000000003172 115.0
PYH2_k127_1674944_4 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000005632 105.0
PYH2_k127_1687544_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 458.0
PYH2_k127_1687544_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 349.0
PYH2_k127_1687544_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000002075 123.0
PYH2_k127_1698775_0 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 497.0
PYH2_k127_1698775_1 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 376.0
PYH2_k127_1698775_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001539 263.0
PYH2_k127_1698775_3 diol metabolic process K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000008525 171.0
PYH2_k127_1698775_4 Putative prokaryotic signal transducing protein - - - 0.00000000002853 67.0
PYH2_k127_1702313_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 411.0
PYH2_k127_1702313_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
PYH2_k127_1719537_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1115.0
PYH2_k127_1719537_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 362.0
PYH2_k127_1719537_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000001955 229.0
PYH2_k127_1719537_3 Oligoketide cyclase lipid transport protein - - - 0.00000000000000000000000000000000000009867 146.0
PYH2_k127_1719537_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000533 76.0
PYH2_k127_1719537_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000006771 77.0
PYH2_k127_1720028_0 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 469.0
PYH2_k127_1720028_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
PYH2_k127_1720028_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 381.0
PYH2_k127_1720028_3 Thioesterase superfamily - - - 0.0000000000000000000000000000006829 137.0
PYH2_k127_1727231_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 6.369e-277 867.0
PYH2_k127_1727231_1 Pantoate-beta-alanine ligase K01918 - 6.3.2.1 0.00000000000001724 74.0
PYH2_k127_1727850_0 Hydantoinase/oxoprolinase - - - 5.852e-202 649.0
PYH2_k127_1727850_1 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 312.0
PYH2_k127_1727850_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000001674 173.0
PYH2_k127_1741547_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.934e-292 905.0
PYH2_k127_1741547_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 553.0
PYH2_k127_1741547_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003018 266.0
PYH2_k127_1741547_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
PYH2_k127_1741547_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000003667 224.0
PYH2_k127_1741547_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000001401 172.0
PYH2_k127_1741547_6 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000000000003814 93.0
PYH2_k127_1748366_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 437.0
PYH2_k127_1748366_1 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 419.0
PYH2_k127_1748366_2 AsmA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 430.0
PYH2_k127_1748366_3 Putative methyltransferase K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001205 295.0
PYH2_k127_1748366_4 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 279.0
PYH2_k127_1748366_5 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000003655 182.0
PYH2_k127_1748366_6 OsmC-like protein - - - 0.0000000000000000000000000000000000000106 152.0
PYH2_k127_1748366_7 ThiS family K03154 - - 0.00000000000000000002463 92.0
PYH2_k127_1748366_8 - - - - 0.0001856 53.0
PYH2_k127_1778593_0 chemotaxis K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004668 280.0
PYH2_k127_1778593_1 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000002503 222.0
PYH2_k127_1778593_2 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000004522 181.0
PYH2_k127_1778593_3 Chemotaxis signal transduction protein K02659 - - 0.00000000000000000000000000000000000004709 150.0
PYH2_k127_1778593_4 Rubredoxin - - - 0.0000000000000000000000000000005591 123.0
PYH2_k127_1778593_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000008267 111.0
PYH2_k127_1814885_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 543.0
PYH2_k127_1814885_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 447.0
PYH2_k127_1814885_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000004419 141.0
PYH2_k127_1814885_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000007364 80.0
PYH2_k127_1814885_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00009159 48.0
PYH2_k127_1832243_0 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.00000000000000000000000000000000000000000000000008102 184.0
PYH2_k127_1832243_1 PFAM O-methyltransferase, family 3 - - - 0.0000000000000000000000000000000000000000000000007447 177.0
PYH2_k127_1832243_2 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000001832 154.0
PYH2_k127_1842529_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 326.0
PYH2_k127_1842529_1 NnrU protein - - - 0.00000000000000000000000000000000000000000000000001124 187.0
PYH2_k127_1842529_2 Thioesterase - - - 0.00000000000000000000000000000000000002341 149.0
PYH2_k127_1842529_3 aminopeptidase N K01256 - 3.4.11.2 0.0000000000002927 70.0
PYH2_k127_1864422_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 3.431e-250 786.0
PYH2_k127_1864422_1 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 598.0
PYH2_k127_1864422_2 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 411.0
PYH2_k127_1864422_3 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000009068 209.0
PYH2_k127_1873096_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 432.0
PYH2_k127_1879169_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 5.944e-207 649.0
PYH2_k127_1879169_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 508.0
PYH2_k127_1879169_2 Nucleoside-binding outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 340.0
PYH2_k127_1879169_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000003391 160.0
PYH2_k127_1879169_4 receptor - - - 0.0001815 45.0
PYH2_k127_188562_0 Methyl-transferase K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 415.0
PYH2_k127_188562_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003233 273.0
PYH2_k127_188562_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000477 123.0
PYH2_k127_1888217_0 HD domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
PYH2_k127_1888217_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000492 93.0
PYH2_k127_1894652_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 453.0
PYH2_k127_1894652_1 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 397.0
PYH2_k127_1894652_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000003461 68.0
PYH2_k127_1909912_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1391.0
PYH2_k127_1909912_1 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 5.23e-267 875.0
PYH2_k127_1909912_2 Tripartite tricarboxylate transporter TctA family K07793 - - 2.906e-246 767.0
PYH2_k127_1909912_3 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 3.045e-245 767.0
PYH2_k127_1909912_4 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 481.0
PYH2_k127_1909912_5 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 325.0
PYH2_k127_1909912_6 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008744 249.0
PYH2_k127_1909912_7 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000002232 170.0
PYH2_k127_1909912_8 Transcriptional regulator, Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000002158 60.0
PYH2_k127_1934447_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 5.466e-259 814.0
PYH2_k127_1934447_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.115e-252 794.0
PYH2_k127_1934447_2 ABC transporter transmembrane region K02021 - - 1.216e-247 788.0
PYH2_k127_1934447_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 602.0
PYH2_k127_1934447_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 462.0
PYH2_k127_1934447_5 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 361.0
PYH2_k127_1934447_6 - - - - 0.0000000000000000000000000000000001483 139.0
PYH2_k127_1934447_7 polysaccharide deacetylase - - - 0.0000004618 53.0
PYH2_k127_1971503_0 enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000008315 250.0
PYH2_k127_1971503_1 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000537 52.0
PYH2_k127_1980248_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 484.0
PYH2_k127_1980248_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000009906 234.0
PYH2_k127_1980248_2 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000000000000000000000000000000002423 179.0
PYH2_k127_1980248_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000001448 163.0
PYH2_k127_1980248_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000001187 121.0
PYH2_k127_2010065_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 307.0
PYH2_k127_2010065_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 306.0
PYH2_k127_2010065_2 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000001307 130.0
PYH2_k127_2017725_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 301.0
PYH2_k127_2017725_1 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000001496 194.0
PYH2_k127_2017725_2 Cytochrome c - - - 0.000000000000000000000000000000001541 130.0
PYH2_k127_2017725_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000003986 111.0
PYH2_k127_2032595_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 513.0
PYH2_k127_2032595_1 type 4 pilus biogenesis protein K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
PYH2_k127_2032595_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000001098 230.0
PYH2_k127_2032595_3 Enoyl-CoA hydratase - - - 0.0000000000000000000003889 99.0
PYH2_k127_2032595_4 Helix-turn-helix domain K15539 - - 0.00000000000003436 84.0
PYH2_k127_2036295_0 radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 609.0
PYH2_k127_2036295_1 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004511 283.0
PYH2_k127_2036295_2 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000004816 203.0
PYH2_k127_2036295_3 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000003268 180.0
PYH2_k127_2036295_4 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000001461 122.0
PYH2_k127_2050440_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 428.0
PYH2_k127_2050440_1 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 275.0
PYH2_k127_2050440_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000008258 136.0
PYH2_k127_2050440_3 Acylphosphatase K01512 - 3.6.1.7 0.00000000005091 72.0
PYH2_k127_2055098_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.731e-197 632.0
PYH2_k127_2055098_1 protein conserved in bacteria K03690 - - 0.00000000000000000001465 96.0
PYH2_k127_2063954_0 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000006986 255.0
PYH2_k127_2063954_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000001112 202.0
PYH2_k127_2063954_2 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000000000001862 140.0
PYH2_k127_2063954_3 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.00000000000000000000000000000004893 134.0
PYH2_k127_2073684_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.247e-263 828.0
PYH2_k127_2073684_1 belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.387e-215 675.0
PYH2_k127_2079569_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
PYH2_k127_2079569_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 282.0
PYH2_k127_2079569_2 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000004979 229.0
PYH2_k127_2079569_3 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000002527 181.0
PYH2_k127_2079569_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000001787 138.0
PYH2_k127_2123790_0 Branched-chain amino acid transport system / permease component K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 537.0
PYH2_k127_2123790_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 490.0
PYH2_k127_2123790_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 408.0
PYH2_k127_2123790_3 ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 377.0
PYH2_k127_2123790_4 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000001488 87.0
PYH2_k127_2124373_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.78e-214 674.0
PYH2_k127_2124373_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001025 279.0
PYH2_k127_2124373_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000004792 198.0
PYH2_k127_2124373_3 - - - - 0.00000000000000000000000000000000000000003346 159.0
PYH2_k127_2124373_4 MatE - - - 0.00000000000000000000000000001141 121.0
PYH2_k127_2124373_5 Protein of unknown function (DUF3567) - - - 0.00000000000000002949 83.0
PYH2_k127_2125296_0 COG0457 FOG TPR repeat - - - 1.927e-222 701.0
PYH2_k127_2125296_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 398.0
PYH2_k127_2125296_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 291.0
PYH2_k127_2125296_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 314.0
PYH2_k127_2125296_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002455 275.0
PYH2_k127_2125296_5 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009997 251.0
PYH2_k127_2125296_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002839 168.0
PYH2_k127_2125296_7 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000001652 133.0
PYH2_k127_2137722_0 Amidase K02433 - 6.3.5.6,6.3.5.7 2.764e-201 640.0
PYH2_k127_2137722_1 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 460.0
PYH2_k127_2137722_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000005534 86.0
PYH2_k127_2145625_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.015e-289 898.0
PYH2_k127_2145625_1 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 547.0
PYH2_k127_2155694_0 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.0000000000000000000000000000000000000000000000001419 183.0
PYH2_k127_2155694_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000005464 159.0
PYH2_k127_2155694_2 Redoxin - - - 0.0000000000000000000000000000000000000001737 156.0
PYH2_k127_2170894_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 509.0
PYH2_k127_2170894_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000001789 188.0
PYH2_k127_2195029_0 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 524.0
PYH2_k127_2195029_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 445.0
PYH2_k127_2195029_10 carbon monoxide dehydrogenase K09386 - - 0.000000000000000000000000000000000000000001511 177.0
PYH2_k127_2195029_11 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000669 161.0
PYH2_k127_2195029_12 Lipocalin-like domain - - - 0.00000000000002654 79.0
PYH2_k127_2195029_13 Adenylate cyclase K01768 - 4.6.1.1 0.00000001109 67.0
PYH2_k127_2195029_2 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 445.0
PYH2_k127_2195029_3 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 429.0
PYH2_k127_2195029_4 molybdenum cofactor K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006529 274.0
PYH2_k127_2195029_5 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003305 266.0
PYH2_k127_2195029_6 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000006643 226.0
PYH2_k127_2195029_7 Dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000009946 222.0
PYH2_k127_2195029_8 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000004071 199.0
PYH2_k127_2195029_9 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000002771 175.0
PYH2_k127_2207350_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 613.0
PYH2_k127_2207350_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 327.0
PYH2_k127_2207350_2 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000004331 224.0
PYH2_k127_2207350_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000005608 85.0
PYH2_k127_2207350_4 mechanosensitive ion channel K22044 - - 0.0002885 53.0
PYH2_k127_2213787_0 rieske 2fe-2s K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 506.0
PYH2_k127_2213787_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 460.0
PYH2_k127_2213787_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
PYH2_k127_2213787_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 272.0
PYH2_k127_2213787_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000001804 138.0
PYH2_k127_2213787_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000001136 88.0
PYH2_k127_2228405_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 361.0
PYH2_k127_2228405_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
PYH2_k127_2228405_2 Putative serine dehydratase domain K18425 - 4.1.3.41 0.00002631 56.0
PYH2_k127_2241136_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1071.0
PYH2_k127_2241136_1 AMP-binding enzyme C-terminal domain - - - 2.573e-218 690.0
PYH2_k127_2241136_2 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000007784 265.0
PYH2_k127_2241136_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000005048 153.0
PYH2_k127_2241136_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000001141 126.0
PYH2_k127_2241136_5 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000000001645 132.0
PYH2_k127_2241136_6 - - - - 0.0000000000003078 78.0
PYH2_k127_226262_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1310.0
PYH2_k127_226262_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 530.0
PYH2_k127_226262_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 517.0
PYH2_k127_226262_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000003451 246.0
PYH2_k127_226262_4 OmpA family K03286 - - 0.000000007581 59.0
PYH2_k127_2284265_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 488.0
PYH2_k127_2284265_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 420.0
PYH2_k127_2284265_2 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 359.0
PYH2_k127_2284265_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 349.0
PYH2_k127_2284265_4 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000003178 65.0
PYH2_k127_2289340_0 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
PYH2_k127_2289340_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000003008 182.0
PYH2_k127_2289340_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.0000000000000000000000000000005749 137.0
PYH2_k127_2289340_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0004488 47.0
PYH2_k127_2305497_0 MMPL family - - - 0.0 1310.0
PYH2_k127_2305497_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.715e-196 627.0
PYH2_k127_2305497_2 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 441.0
PYH2_k127_2305497_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 347.0
PYH2_k127_2305497_4 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 278.0
PYH2_k127_2305497_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002176 271.0
PYH2_k127_2305497_6 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000004701 171.0
PYH2_k127_2305497_7 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000001483 69.0
PYH2_k127_230934_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 426.0
PYH2_k127_230934_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
PYH2_k127_230934_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000005944 99.0
PYH2_k127_231786_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 571.0
PYH2_k127_231786_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 339.0
PYH2_k127_231786_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 289.0
PYH2_k127_2325120_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1039.0
PYH2_k127_2335999_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 420.0
PYH2_k127_2335999_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 327.0
PYH2_k127_2335999_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000002829 229.0
PYH2_k127_2335999_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000005698 191.0
PYH2_k127_2335999_4 Redoxin domain protein - - - 0.00000000000000000000000000000000000000001304 160.0
PYH2_k127_2356309_0 amino acid - - - 1.516e-278 879.0
PYH2_k127_2356309_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022 - - 0.000000000000000000000000000000000000000000000000000000000000005866 222.0
PYH2_k127_2356309_2 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000001616 190.0
PYH2_k127_2356309_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000006233 180.0
PYH2_k127_2356309_4 SapC - - - 0.000000000000000000000000000000000000000004171 164.0
PYH2_k127_2356309_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000001995 160.0
PYH2_k127_2356309_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000001902 119.0
PYH2_k127_2358089_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 458.0
PYH2_k127_2358089_1 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000201 265.0
PYH2_k127_2358089_2 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001417 236.0
PYH2_k127_2358913_0 Protein of unknown function (DUF1302) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 512.0
PYH2_k127_2358913_1 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 375.0
PYH2_k127_2358913_10 Secretin and TonB N terminus short domain K02453 - - 0.00001202 57.0
PYH2_k127_2358913_2 PFAM type II secretion system K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 296.0
PYH2_k127_2358913_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001349 264.0
PYH2_k127_2358913_4 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
PYH2_k127_2358913_5 Sigma factor PP2C-like phosphatases K07315,K07680 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000000000000000008539 225.0
PYH2_k127_2358913_6 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000002965 194.0
PYH2_k127_2358913_7 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000000000009958 132.0
PYH2_k127_2358913_8 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000004461 109.0
PYH2_k127_2358913_9 - - - - 0.00000002243 65.0
PYH2_k127_2410606_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.08e-229 724.0
PYH2_k127_2410606_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000008543 175.0
PYH2_k127_2410606_2 PFAM regulatory protein MerR - - - 0.000000000000000000000000000000000000000000000001373 180.0
PYH2_k127_2410606_3 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.000000000000000000000000000000000000000002002 160.0
PYH2_k127_2410606_4 Diacylglycerol kinase K07029 - 2.7.1.107 0.00000000000000000000000742 106.0
PYH2_k127_2410606_5 - - - - 0.000002366 53.0
PYH2_k127_248758_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.451e-241 764.0
PYH2_k127_248758_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001193 229.0
PYH2_k127_248758_2 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.0000000001998 61.0
PYH2_k127_2521028_0 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 310.0
PYH2_k127_2521028_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
PYH2_k127_2521028_10 Lipase (class 3) - - - 0.0000106 59.0
PYH2_k127_2521028_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004106 296.0
PYH2_k127_2521028_3 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
PYH2_k127_2521028_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005838 229.0
PYH2_k127_2521028_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000482 191.0
PYH2_k127_2521028_6 - - - - 0.000000000000000000000000000000000000000388 157.0
PYH2_k127_2521028_7 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000003071 131.0
PYH2_k127_2521028_8 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000248 128.0
PYH2_k127_2521028_9 - - - - 0.000000000001798 71.0
PYH2_k127_2536116_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1058.0
PYH2_k127_2536116_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1031.0
PYH2_k127_2536116_2 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 9.91e-212 668.0
PYH2_k127_2536116_3 HI0933-like protein - - - 1.435e-209 657.0
PYH2_k127_2536116_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 467.0
PYH2_k127_2536116_5 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 310.0
PYH2_k127_2552792_0 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 5.933e-267 842.0
PYH2_k127_2552792_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 521.0
PYH2_k127_2552792_10 Outer membrane lipoprotein LolB - - - 0.00001476 48.0
PYH2_k127_2552792_12 - - - - 0.0009522 42.0
PYH2_k127_2552792_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 511.0
PYH2_k127_2552792_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 456.0
PYH2_k127_2552792_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 374.0
PYH2_k127_2552792_5 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 327.0
PYH2_k127_2552792_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005864 250.0
PYH2_k127_2552792_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000518 232.0
PYH2_k127_2552792_8 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000004405 83.0
PYH2_k127_257139_0 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 359.0
PYH2_k127_257139_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 348.0
PYH2_k127_257139_2 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003975 249.0
PYH2_k127_257139_3 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000025 108.0
PYH2_k127_2572998_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 3.176e-292 924.0
PYH2_k127_2572998_1 PFAM AFG1-family ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 443.0
PYH2_k127_2572998_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 398.0
PYH2_k127_2572998_3 EamA-like transporter family - - - 0.0000000000000000000000001272 107.0
PYH2_k127_2572998_4 Haem-degrading - - - 0.00006354 54.0
PYH2_k127_2573307_0 response regulator K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 531.0
PYH2_k127_2573307_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 439.0
PYH2_k127_2573307_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000783 247.0
PYH2_k127_257954_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 5.763e-274 859.0
PYH2_k127_257954_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 550.0
PYH2_k127_257954_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 541.0
PYH2_k127_257954_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009561 258.0
PYH2_k127_257954_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000008899 231.0
PYH2_k127_264617_0 - - - - 1.69e-235 758.0
PYH2_k127_264617_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
PYH2_k127_264617_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
PYH2_k127_264617_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001341 282.0
PYH2_k127_264617_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001875 246.0
PYH2_k127_264617_5 MAPEG family - - - 0.000000000000000000000000000000000000000001884 160.0
PYH2_k127_264617_6 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000002511 148.0
PYH2_k127_2731110_0 Haem-degrading - - - 0.00000000000000000000000000000000000000000000003484 179.0
PYH2_k127_2731110_1 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000002212 178.0
PYH2_k127_2731110_2 Haem-degrading - - - 0.0000000000000000004558 89.0
PYH2_k127_2764893_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 1.932e-266 835.0
PYH2_k127_2764893_1 Isocitrate lyase K01637 - 4.1.3.1 3.108e-225 705.0
PYH2_k127_2764893_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 482.0
PYH2_k127_2764893_3 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000007408 187.0
PYH2_k127_2769629_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 409.0
PYH2_k127_2769629_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 287.0
PYH2_k127_2769629_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 259.0
PYH2_k127_2769629_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003956 248.0
PYH2_k127_2769629_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000001105 121.0
PYH2_k127_2769629_5 CNP1-like family - - - 0.00000000000000000000000000006402 128.0
PYH2_k127_2777508_0 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000002343 241.0
PYH2_k127_2777508_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000005392 188.0
PYH2_k127_2777508_2 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000184 182.0
PYH2_k127_2781684_0 Heat shock 70 kDa protein K04043 - - 0.0 1053.0
PYH2_k127_2781684_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 454.0
PYH2_k127_2781684_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 354.0
PYH2_k127_2781684_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009477 248.0
PYH2_k127_2781684_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000003796 154.0
PYH2_k127_2781684_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00005664 47.0
PYH2_k127_2790189_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 7.693e-248 778.0
PYH2_k127_2790189_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 452.0
PYH2_k127_2790189_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000001727 198.0
PYH2_k127_2790189_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000006918 187.0
PYH2_k127_2790189_4 - - - - 0.000000000000000000000000000000000000000000005515 170.0
PYH2_k127_2790189_5 Redoxin family - - - 0.00000000000000000000000000000000001199 146.0
PYH2_k127_2790189_6 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000346 98.0
PYH2_k127_2801066_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 565.0
PYH2_k127_2801066_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000002701 135.0
PYH2_k127_2868752_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 1.218e-228 717.0
PYH2_k127_2868752_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 601.0
PYH2_k127_2868752_2 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 494.0
PYH2_k127_2868752_3 Tripartite ATP-independent periplasmic transporter - - - 0.0000000000000000000000000000000000000000000000000000000000001165 220.0
PYH2_k127_2868752_4 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.00000000000000000000000000000000000000000000001747 171.0
PYH2_k127_2895667_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 540.0
PYH2_k127_2895667_1 - - - - 0.0000000000000007053 86.0
PYH2_k127_2895667_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.0000004944 52.0
PYH2_k127_2918817_0 Class II Aldolase and Adducin N-terminal domain - - - 7.911e-272 853.0
PYH2_k127_2918817_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 385.0
PYH2_k127_2918817_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
PYH2_k127_2918817_3 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000003739 209.0
PYH2_k127_2918817_4 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000001954 209.0
PYH2_k127_2918817_5 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000001228 197.0
PYH2_k127_2918817_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004611 168.0
PYH2_k127_2918817_7 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000005032 87.0
PYH2_k127_2918817_8 Domain of unknown function (DUF4936) - - - 0.000202 55.0
PYH2_k127_2926899_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 7.405e-286 891.0
PYH2_k127_2926899_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 356.0
PYH2_k127_2926899_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
PYH2_k127_2926899_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000001722 205.0
PYH2_k127_2926899_4 Belongs to the SUA5 family - - - 0.0000000000000000001099 89.0
PYH2_k127_2934179_0 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 396.0
PYH2_k127_2934179_1 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
PYH2_k127_2936556_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 5.535e-221 697.0
PYH2_k127_2936556_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 492.0
PYH2_k127_2943537_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2208.0
PYH2_k127_2943537_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1996.0
PYH2_k127_2943537_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000029 117.0
PYH2_k127_2948576_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 528.0
PYH2_k127_2948576_1 Adenylate guanylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000007143 156.0
PYH2_k127_2948576_2 - - - - 0.000003462 50.0
PYH2_k127_2993369_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 619.0
PYH2_k127_2993369_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 616.0
PYH2_k127_2993369_2 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 572.0
PYH2_k127_2993369_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 464.0
PYH2_k127_2993369_4 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 285.0
PYH2_k127_2993369_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000156 270.0
PYH2_k127_3005256_0 AcrB/AcrD/AcrF family - - - 1.497e-302 945.0
PYH2_k127_3005256_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000415 260.0
PYH2_k127_3005256_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000008291 102.0
PYH2_k127_3007369_0 Carboxyl transferase domain - - - 3.967e-211 667.0
PYH2_k127_3007369_1 - - - - 0.00000000000000000000000007661 124.0
PYH2_k127_3017056_0 Secretin and TonB N terminus short domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 582.0
PYH2_k127_3017056_1 carbon utilization - - - 0.0000000000000002101 83.0
PYH2_k127_3024679_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.47e-291 908.0
PYH2_k127_3024679_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 586.0
PYH2_k127_3024679_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 555.0
PYH2_k127_3024679_3 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 352.0
PYH2_k127_3024679_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 296.0
PYH2_k127_3024679_5 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000009772 220.0
PYH2_k127_3024679_6 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000005508 190.0
PYH2_k127_3044597_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 5.28e-262 834.0
PYH2_k127_3044597_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 1.04e-236 751.0
PYH2_k127_3044597_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 531.0
PYH2_k127_3044597_3 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 450.0
PYH2_k127_3044597_4 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004751 295.0
PYH2_k127_3044597_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009069 270.0
PYH2_k127_3044597_6 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.0000000000000000000000000000000000008512 139.0
PYH2_k127_3044597_7 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000001798 130.0
PYH2_k127_30523_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
PYH2_k127_30523_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004509 284.0
PYH2_k127_30523_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000169 154.0
PYH2_k127_30523_3 overlaps another CDS with the same product name K07240 - - 0.000000000000000000000000000000000059 138.0
PYH2_k127_3052502_0 Phosphoesterase family - - - 1.786e-201 642.0
PYH2_k127_3052502_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 377.0
PYH2_k127_3052502_2 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
PYH2_k127_3052502_3 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
PYH2_k127_3052502_4 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000000005071 158.0
PYH2_k127_3052502_5 - - - - 0.0000000000000000000187 97.0
PYH2_k127_3078907_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 547.0
PYH2_k127_3078907_1 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000003094 194.0
PYH2_k127_3078907_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000156 138.0
PYH2_k127_3079630_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 518.0
PYH2_k127_3079630_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 482.0
PYH2_k127_3079630_2 Zinc-finger domain - - - 0.0000000000000000001164 101.0
PYH2_k127_3079630_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00006729 48.0
PYH2_k127_3091597_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.019e-289 893.0
PYH2_k127_3091597_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 494.0
PYH2_k127_3091597_2 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 376.0
PYH2_k127_3091597_3 oxidase assembly K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008407 242.0
PYH2_k127_3091597_4 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000003849 207.0
PYH2_k127_3091597_5 Protein of unknown function (DUF2909) - - - 0.0000000000007256 72.0
PYH2_k127_3091597_6 Protein of unknown function (DUF2970) - - - 0.0008198 50.0
PYH2_k127_3096179_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1144.0
PYH2_k127_3096179_1 CHASE2 K01768 - 4.6.1.1 4.237e-270 850.0
PYH2_k127_3096179_2 metal-dependent phosphohydrolase HD sub domain - - - 1.824e-238 749.0
PYH2_k127_3096179_3 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 449.0
PYH2_k127_3096179_4 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
PYH2_k127_3096179_5 (FHA) domain - - - 0.0000000000000000000000000000000004558 132.0
PYH2_k127_3096179_6 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.000000000000000000000000000000002747 130.0
PYH2_k127_3096179_7 - - - - 0.00000002117 61.0
PYH2_k127_309809_0 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 343.0
PYH2_k127_309809_1 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000001824 188.0
PYH2_k127_309809_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000002285 82.0
PYH2_k127_309809_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000003649 79.0
PYH2_k127_3108696_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 467.0
PYH2_k127_3108696_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 476.0
PYH2_k127_3108696_2 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 342.0
PYH2_k127_3108696_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 269.0
PYH2_k127_3108696_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000005059 140.0
PYH2_k127_3108696_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000001252 125.0
PYH2_k127_3116003_0 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 288.0
PYH2_k127_3116003_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000345 182.0
PYH2_k127_3116003_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000001018 158.0
PYH2_k127_3134888_0 Pfam:DUF1446 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 552.0
PYH2_k127_3134888_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000112 194.0
PYH2_k127_3158465_0 TrkA-N domain protein K03499 - - 2.029e-198 632.0
PYH2_k127_3158465_1 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 430.0
PYH2_k127_3158465_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 414.0
PYH2_k127_3190280_0 AMP-binding enzyme C-terminal domain K00666 - - 5.707e-227 715.0
PYH2_k127_3190280_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 489.0
PYH2_k127_3190280_10 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000006291 191.0
PYH2_k127_3190280_11 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000007809 184.0
PYH2_k127_3190280_2 L-phenylalanine transmembrane transporter activity K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 400.0
PYH2_k127_3190280_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 309.0
PYH2_k127_3190280_4 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
PYH2_k127_3190280_5 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004046 274.0
PYH2_k127_3190280_6 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004091 274.0
PYH2_k127_3190280_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
PYH2_k127_3190280_8 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000005422 271.0
PYH2_k127_3190280_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
PYH2_k127_3201506_0 Belongs to the GMC oxidoreductase family - - - 2.806e-195 630.0
PYH2_k127_3201506_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 540.0
PYH2_k127_3201506_10 RDD family - - - 0.0000000000000000000000000000000000000000000000006198 179.0
PYH2_k127_3201506_11 Major facilitator Superfamily - - - 0.0000000000000000000000000005297 115.0
PYH2_k127_3201506_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000001597 99.0
PYH2_k127_3201506_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 521.0
PYH2_k127_3201506_3 13-prostaglandin reductase activity K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
PYH2_k127_3201506_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 354.0
PYH2_k127_3201506_5 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 345.0
PYH2_k127_3201506_6 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 342.0
PYH2_k127_3201506_7 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 323.0
PYH2_k127_3201506_8 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 323.0
PYH2_k127_3201506_9 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 314.0
PYH2_k127_3217965_0 (ABC) transporter K11004,K13409 - - 6.727e-213 676.0
PYH2_k127_3227669_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1221.0
PYH2_k127_3227669_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.225e-284 895.0
PYH2_k127_3227669_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 604.0
PYH2_k127_3227669_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.00000000000000000000000000000000000000003562 153.0
PYH2_k127_3227669_4 membrane - - - 0.000000000000000000000000000000000002746 142.0
PYH2_k127_3227669_5 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000000000000000000000001432 135.0
PYH2_k127_3227669_6 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000003481 141.0
PYH2_k127_3227669_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000001411 96.0
PYH2_k127_3233075_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 556.0
PYH2_k127_3233075_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000002177 128.0
PYH2_k127_3233075_2 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000001933 101.0
PYH2_k127_3233532_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.081e-212 674.0
PYH2_k127_3233532_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 556.0
PYH2_k127_3233532_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 432.0
PYH2_k127_3233532_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 303.0
PYH2_k127_3233532_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000001064 188.0
PYH2_k127_3233532_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000001267 198.0
PYH2_k127_3233532_6 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000001606 120.0
PYH2_k127_3265549_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 600.0
PYH2_k127_3265549_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 539.0
PYH2_k127_3265549_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 497.0
PYH2_k127_3265549_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000003702 229.0
PYH2_k127_3265549_4 Porin subfamily - - - 0.00000000000000000000000000000000000005879 159.0
PYH2_k127_3265549_5 - - - - 0.0000000005413 68.0
PYH2_k127_3265549_6 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000004085 55.0
PYH2_k127_3268793_0 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 551.0
PYH2_k127_3268793_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 498.0
PYH2_k127_3268793_2 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 414.0
PYH2_k127_3268793_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000109 259.0
PYH2_k127_3268793_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
PYH2_k127_3268793_5 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000006799 212.0
PYH2_k127_3268793_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001378 188.0
PYH2_k127_3268793_7 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000004172 184.0
PYH2_k127_3268793_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000001274 175.0
PYH2_k127_3268793_9 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000004544 95.0
PYH2_k127_3274970_0 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
PYH2_k127_3274970_1 mechanosensitive K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 314.0
PYH2_k127_3274970_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000104 189.0
PYH2_k127_3274970_3 - - - - 0.0000000000000000000000000000000000000000004733 168.0
PYH2_k127_3280191_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
PYH2_k127_3280191_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 526.0
PYH2_k127_3280191_10 Protein of unknown function (DUF2817) - - - 0.0000000005318 65.0
PYH2_k127_3280191_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 537.0
PYH2_k127_3280191_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 402.0
PYH2_k127_3280191_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 324.0
PYH2_k127_3280191_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
PYH2_k127_3280191_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
PYH2_k127_3280191_7 NIPSNAP - - - 0.000000000000000000000000000000000000000000000007723 176.0
PYH2_k127_3280191_8 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000329 153.0
PYH2_k127_3280191_9 Cupin 2, conserved barrel K21700 - - 0.00000000000000000000000000000003508 133.0
PYH2_k127_3294128_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.493e-255 797.0
PYH2_k127_3294128_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 479.0
PYH2_k127_3294128_10 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000002802 134.0
PYH2_k127_3294128_11 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000001522 150.0
PYH2_k127_3294128_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 410.0
PYH2_k127_3294128_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 316.0
PYH2_k127_3294128_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 304.0
PYH2_k127_3294128_5 Thiosulfate-oxidizing multienzyme system protein SoxA K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 288.0
PYH2_k127_3294128_6 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000001042 258.0
PYH2_k127_3294128_7 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000001148 186.0
PYH2_k127_3294128_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000009175 195.0
PYH2_k127_3294128_9 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000002303 177.0
PYH2_k127_3295201_0 Phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 505.0
PYH2_k127_3295201_1 phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 289.0
PYH2_k127_3295201_2 protein conserved in bacteria K09796 - - 0.0000000000000000000000000004073 116.0
PYH2_k127_3295201_3 PFAM CoA-transferase family III K01796 - 5.1.99.4 0.0002031 44.0
PYH2_k127_3315327_0 response regulator K02481 - - 4.705e-214 679.0
PYH2_k127_3315327_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 577.0
PYH2_k127_3315327_10 4-carboxy-4-hydroxy-2-oxoadipate aldolase oxaloacetate decarboxylase K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004398 303.0
PYH2_k127_3315327_11 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000419 279.0
PYH2_k127_3315327_12 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003594 275.0
PYH2_k127_3315327_13 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001209 258.0
PYH2_k127_3315327_14 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000005767 235.0
PYH2_k127_3315327_15 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000004325 231.0
PYH2_k127_3315327_16 response regulator - - - 0.00000000000000000000000000000000000000000000000000003461 198.0
PYH2_k127_3315327_17 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000003178 167.0
PYH2_k127_3315327_2 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 527.0
PYH2_k127_3315327_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 421.0
PYH2_k127_3315327_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 389.0
PYH2_k127_3315327_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 379.0
PYH2_k127_3315327_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 357.0
PYH2_k127_3315327_7 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 343.0
PYH2_k127_3315327_8 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 331.0
PYH2_k127_3315327_9 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 325.0
PYH2_k127_3354592_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 288.0
PYH2_k127_3354592_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
PYH2_k127_3354592_2 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000003205 268.0
PYH2_k127_3354592_3 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000009526 264.0
PYH2_k127_3354592_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.00000000000000000000000000000000000000000000000002034 190.0
PYH2_k127_3354592_5 -Thioesterase K01075 - 3.1.2.23 0.000000000000000000004889 98.0
PYH2_k127_3354620_0 Tripartite tricarboxylate transporter TctA family - - - 8.666e-226 708.0
PYH2_k127_3354620_1 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000009374 110.0
PYH2_k127_3368288_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 457.0
PYH2_k127_3368288_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 407.0
PYH2_k127_3368288_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH2_k127_3368288_3 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 327.0
PYH2_k127_3368288_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 282.0
PYH2_k127_3368288_5 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
PYH2_k127_3368288_6 Protein of unknown function (DUF2892) - - - 0.000000000000000000523 94.0
PYH2_k127_3368288_7 NUDIX hydrolase - - - 0.000000003999 68.0
PYH2_k127_3386203_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1141.0
PYH2_k127_3386203_1 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 551.0
PYH2_k127_3386203_2 Alcohol dehydrogenase GroES-like domain K00001 GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004022,GO:0004552,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0007610,GO:0007611,GO:0007612,GO:0007632,GO:0008150,GO:0008152,GO:0008306,GO:0008542,GO:0009314,GO:0009416,GO:0009628,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016657,GO:0019222,GO:0031323,GO:0031399,GO:0032268,GO:0032501,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051171,GO:0051246,GO:0051903,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080007,GO:0080090,GO:0080164,GO:1901615,GO:2000169,GO:2000377 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 310.0
PYH2_k127_3386203_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000001416 130.0
PYH2_k127_3403769_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 8.782e-228 736.0
PYH2_k127_3403769_1 FAD binding domain K07077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 483.0
PYH2_k127_3403769_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000106 85.0
PYH2_k127_3443995_0 RND efflux system, outer membrane lipoprotein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 309.0
PYH2_k127_3443995_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000002484 204.0
PYH2_k127_3445669_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 3.321e-240 755.0
PYH2_k127_3445669_1 type II secretion system protein K02653 - - 2.101e-197 622.0
PYH2_k127_3445669_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000006748 231.0
PYH2_k127_3445669_11 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000005674 176.0
PYH2_k127_3445669_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000001009 141.0
PYH2_k127_3445669_13 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000003067 119.0
PYH2_k127_3445669_14 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000002547 86.0
PYH2_k127_3445669_15 - - - - 0.000000000000129 73.0
PYH2_k127_3445669_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 612.0
PYH2_k127_3445669_3 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 455.0
PYH2_k127_3445669_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 390.0
PYH2_k127_3445669_5 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 370.0
PYH2_k127_3445669_6 SMART AAA ATPase K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 364.0
PYH2_k127_3445669_7 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 356.0
PYH2_k127_3445669_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 317.0
PYH2_k127_3445669_9 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
PYH2_k127_3453779_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 418.0
PYH2_k127_3453779_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 417.0
PYH2_k127_3453779_2 Lipocalin-like domain - - - 0.0000000004722 64.0
PYH2_k127_3461762_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969,K13778 - 6.4.1.4,6.4.1.5 1.972e-232 743.0
PYH2_k127_3461762_1 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 351.0
PYH2_k127_3461762_2 PFAM Acyl-CoA dehydrogenase K11731 - - 0.000000000000000000000000000000000000000002774 156.0
PYH2_k127_3508410_0 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000006068 244.0
PYH2_k127_3508410_1 FecR protein - - - 0.000000000000000004116 96.0
PYH2_k127_3533858_0 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 350.0
PYH2_k127_3533858_1 CoA binding domain - - - 0.000000000000000000000000000000000000000000001843 169.0
PYH2_k127_3533858_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000005243 94.0
PYH2_k127_3533858_3 lipid A biosynthesis lauroyl acyltransferase K02517 - 2.3.1.241 0.00000000000000112 78.0
PYH2_k127_3538951_0 Glucose inhibited division protein A - - - 3.79e-215 697.0
PYH2_k127_3538951_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 312.0
PYH2_k127_3538951_2 haemagglutination activity domain - - - 0.000000000000000000000000000000000000000000004587 186.0
PYH2_k127_3538951_3 FecR protein - - - 0.00000000000000000000000000000000000000000103 171.0
PYH2_k127_3586017_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 7.951e-194 614.0
PYH2_k127_3586017_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 478.0
PYH2_k127_3586017_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 421.0
PYH2_k127_3586017_3 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 304.0
PYH2_k127_3586017_4 Protein of unknown function (DUF721) - - - 0.000000001142 70.0
PYH2_k127_3586017_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000001652 56.0
PYH2_k127_3588965_0 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 473.0
PYH2_k127_3588965_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 377.0
PYH2_k127_3588965_2 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 340.0
PYH2_k127_3588965_3 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003816 258.0
PYH2_k127_3588965_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000008681 228.0
PYH2_k127_3588965_5 Outer membrane protein beta-barrel domain - - - 0.00000000000005083 83.0
PYH2_k127_3603054_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000009455 228.0
PYH2_k127_3611044_0 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 465.0
PYH2_k127_3611044_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 340.0
PYH2_k127_3611044_2 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
PYH2_k127_3611044_3 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000069 224.0
PYH2_k127_3611044_4 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000001686 223.0
PYH2_k127_3611044_5 HNH nucleases - - - 0.000000000000000000000000000000000000007477 147.0
PYH2_k127_3611044_6 - - - - 0.0000000000000000000000000000000003871 134.0
PYH2_k127_3611044_7 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000002793 119.0
PYH2_k127_3611044_8 TspO/MBR family K05770 - - 0.0000000000000000000000000004646 115.0
PYH2_k127_3626728_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001922 177.0
PYH2_k127_363746_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 310.0
PYH2_k127_363746_1 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000009659 159.0
PYH2_k127_363746_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000001918 85.0
PYH2_k127_364617_0 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 308.0
PYH2_k127_364617_1 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000313 190.0
PYH2_k127_364617_2 Iron-containing alcohol dehydrogenase - - - 0.00000000001551 68.0
PYH2_k127_3696373_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 461.0
PYH2_k127_3696373_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 321.0
PYH2_k127_3696373_2 Protein of unknown function (DUF3467) - - - 0.000000000000111 74.0
PYH2_k127_3711847_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.02e-206 659.0
PYH2_k127_3711847_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 2.962e-205 653.0
PYH2_k127_3711847_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 606.0
PYH2_k127_3711847_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 537.0
PYH2_k127_3711847_4 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 497.0
PYH2_k127_3711847_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 400.0
PYH2_k127_3711847_6 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 305.0
PYH2_k127_3711847_7 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000001156 250.0
PYH2_k127_3711847_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000009966 213.0
PYH2_k127_3711847_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000006132 53.0
PYH2_k127_3712960_0 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 462.0
PYH2_k127_3712960_1 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000001339 206.0
PYH2_k127_3712960_2 EamA-like transporter family - - - 0.0000000000000000000000000000000374 136.0
PYH2_k127_3723274_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 323.0
PYH2_k127_3723274_1 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000001351 180.0
PYH2_k127_3723274_2 - - - - 0.00000000000000000000000002582 114.0
PYH2_k127_3723274_3 - - - - 0.0000000000000000000001149 102.0
PYH2_k127_3727974_0 TonB-dependent receptor K02014 - - 4.304e-210 675.0
PYH2_k127_3727974_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 324.0
PYH2_k127_3727974_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
PYH2_k127_3759141_0 Hydantoinase B/oxoprolinase - - - 6.28e-284 880.0
PYH2_k127_3759141_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000004093 262.0
PYH2_k127_3759141_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000004499 72.0
PYH2_k127_3785464_0 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 363.0
PYH2_k127_3785464_1 PFAM Bacterial Ig-like domain (group 2) - - - 0.00000000000000000000000008004 118.0
PYH2_k127_3803786_0 PFAM extracellular solute-binding protein family 1 K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 565.0
PYH2_k127_3803786_1 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 462.0
PYH2_k127_3803786_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 440.0
PYH2_k127_3803786_3 transporter permease K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 422.0
PYH2_k127_3803786_4 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 407.0
PYH2_k127_3803786_5 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000249 108.0
PYH2_k127_3806008_0 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000009908 201.0
PYH2_k127_3806008_1 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000001079 154.0
PYH2_k127_3806008_2 Sporulation related domain - - - 0.00000000000000000000000000000000003095 138.0
PYH2_k127_3806008_3 Rhodanese-like domain - - - 0.0000000000000000000000000000442 123.0
PYH2_k127_3806008_4 KR domain - - - 0.0000000000000006051 79.0
PYH2_k127_3809119_0 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 339.0
PYH2_k127_3809119_1 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000197 229.0
PYH2_k127_3809119_2 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000007267 171.0
PYH2_k127_3809119_3 NIPSNAP - - - 0.000000000000000000000000000000000000000004253 157.0
PYH2_k127_3817085_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 535.0
PYH2_k127_3817085_1 Beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 497.0
PYH2_k127_3817085_2 transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
PYH2_k127_3817085_3 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 402.0
PYH2_k127_3817085_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000004785 234.0
PYH2_k127_3817085_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000005652 243.0
PYH2_k127_3817085_6 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000004259 195.0
PYH2_k127_3817085_7 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000003737 180.0
PYH2_k127_3817085_8 Transcriptional regulator - - - 0.000000000000000003852 86.0
PYH2_k127_38299_0 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 609.0
PYH2_k127_38299_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 513.0
PYH2_k127_38299_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 326.0
PYH2_k127_38299_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002492 250.0
PYH2_k127_38299_4 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000005515 233.0
PYH2_k127_38299_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000004331 204.0
PYH2_k127_38299_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000001064 181.0
PYH2_k127_38299_7 small protein containing a coiled-coil domain - - - 0.00000000000001117 76.0
PYH2_k127_38299_8 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000006352 76.0
PYH2_k127_3833724_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 6.263e-270 847.0
PYH2_k127_3833724_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
PYH2_k127_3833724_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000003961 118.0
PYH2_k127_3835619_0 Transporter - - - 5.826e-214 698.0
PYH2_k127_3835619_1 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
PYH2_k127_3835619_2 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000004688 187.0
PYH2_k127_3835619_3 Passenger-associated-transport-repeat - - - 0.00000000000000000001139 103.0
PYH2_k127_3835619_4 Major facilitator Superfamily - - - 0.000000000104 75.0
PYH2_k127_3837499_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 574.0
PYH2_k127_3837499_1 PFAM HpcH HpaI aldolase citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
PYH2_k127_3837499_2 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
PYH2_k127_3837499_3 nucleic-acid-binding protein contains PIN domain - - - 0.000000000000000000000000003919 116.0
PYH2_k127_3837499_4 Domain of unknown function (DUF4410) - - - 0.0003498 50.0
PYH2_k127_3846336_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.009e-251 784.0
PYH2_k127_3846336_1 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 484.0
PYH2_k127_3846336_2 carbohydrate phosphatase activity K01086 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 432.0
PYH2_k127_3846336_3 subfamily IA, variant 3 - - - 0.000000000000000000000007359 104.0
PYH2_k127_3858939_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 466.0
PYH2_k127_3858939_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
PYH2_k127_3858939_2 Universal stress protein family - - - 0.000000000000000000003672 100.0
PYH2_k127_3862183_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
PYH2_k127_3862183_1 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
PYH2_k127_3862183_2 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000002713 165.0
PYH2_k127_3862183_3 Fumarate reductase subunit C - - - 0.00000000000000000000000000001526 132.0
PYH2_k127_3862183_4 Fumarate reductase subunit D - - - 0.000000000000000000000007359 104.0
PYH2_k127_3868251_0 alpha/beta hydrolase fold K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 358.0
PYH2_k127_3868251_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000599 232.0
PYH2_k127_3868251_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000253 216.0
PYH2_k127_3868251_3 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000002775 163.0
PYH2_k127_3887504_0 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
PYH2_k127_3887504_1 membrane - - - 0.0000000000000000000000000000000000000000000000000901 183.0
PYH2_k127_3887504_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000002974 136.0
PYH2_k127_3887504_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000533 54.0
PYH2_k127_3887504_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00004166 50.0
PYH2_k127_3889358_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 597.0
PYH2_k127_3889358_1 AMMECR1 - - - 0.0000000000000000000002394 98.0
PYH2_k127_3889358_2 Sel1-like repeats. - - - 0.00001089 53.0
PYH2_k127_3890501_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 2.104e-202 634.0
PYH2_k127_3890501_1 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000000000000000004334 198.0
PYH2_k127_3890501_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000005106 161.0
PYH2_k127_3890501_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000002372 151.0
PYH2_k127_3890501_4 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.00000000000000000002488 91.0
PYH2_k127_3893515_0 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
PYH2_k127_3893515_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 332.0
PYH2_k127_3893515_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000001534 236.0
PYH2_k127_3904039_0 PFAM AMP-dependent synthetase and ligase K00666 - - 6.146e-204 650.0
PYH2_k127_3920862_0 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
PYH2_k127_3920862_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000001021 211.0
PYH2_k127_3920862_2 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000123 177.0
PYH2_k127_3920862_3 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000001604 157.0
PYH2_k127_3923811_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1246.0
PYH2_k127_3923811_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.211e-206 653.0
PYH2_k127_3923811_2 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000006976 134.0
PYH2_k127_3933637_0 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
PYH2_k127_3933637_1 Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000000002078 158.0
PYH2_k127_3933637_2 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000005894 117.0
PYH2_k127_3940138_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.213e-208 662.0
PYH2_k127_3940138_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000126 82.0
PYH2_k127_3940138_2 cell division protein - - - 0.00000004199 57.0
PYH2_k127_3958252_0 Rod shape-determining protein MreB K03569 - - 3.38e-201 630.0
PYH2_k127_3958252_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000001191 248.0
PYH2_k127_3958252_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000005928 105.0
PYH2_k127_3958252_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000002957 80.0
PYH2_k127_4010809_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 391.0
PYH2_k127_4010809_1 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005594 279.0
PYH2_k127_4010809_2 Major facilitator superfamily - - - 0.000000000000000000000000000000001983 136.0
PYH2_k127_4017355_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 568.0
PYH2_k127_4110750_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 541.0
PYH2_k127_4110750_1 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 468.0
PYH2_k127_4132058_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 554.0
PYH2_k127_4132058_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 293.0
PYH2_k127_4132058_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000005921 101.0
PYH2_k127_4199161_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 592.0
PYH2_k127_4199161_1 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000008335 164.0
PYH2_k127_4214452_0 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 3.032e-226 712.0
PYH2_k127_4214452_1 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000001511 109.0
PYH2_k127_423055_0 Alkyl sulfatase C-terminal - - - 2.483e-301 940.0
PYH2_k127_423055_1 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
PYH2_k127_423055_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000001053 220.0
PYH2_k127_423055_3 dienelactone hydrolase - - - 0.0000000006226 62.0
PYH2_k127_4275324_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 467.0
PYH2_k127_4275324_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000002789 258.0
PYH2_k127_4275324_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000005882 183.0
PYH2_k127_4275324_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000104 83.0
PYH2_k127_4300668_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 397.0
PYH2_k127_4300668_1 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001422 281.0
PYH2_k127_4300668_2 Large exoproteins involved in heme utilization or adhesion - - - 0.00000000000000000000000000000000000000000000000000000000000000000003289 241.0
PYH2_k127_4300668_3 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
PYH2_k127_4336219_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1274.0
PYH2_k127_4336219_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 321.0
PYH2_k127_4336219_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 265.0
PYH2_k127_4336219_3 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000002762 236.0
PYH2_k127_4336219_4 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000003183 160.0
PYH2_k127_4336219_5 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.000000000000000003547 97.0
PYH2_k127_4353679_0 Cytochrome D1 heme domain K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 545.0
PYH2_k127_4353679_1 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000004627 193.0
PYH2_k127_4353679_2 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000001095 126.0
PYH2_k127_4353679_3 precorrin-2 dehydrogenase activity K02302,K02303,K02304,K03795,K04719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 0.00000000000000006969 85.0
PYH2_k127_4386083_0 chain 5 L K00341 - 1.6.5.3 1.14e-278 869.0
PYH2_k127_4386083_1 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.364e-247 771.0
PYH2_k127_4386083_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K20961 - 2.7.7.65 0.0000003596 64.0
PYH2_k127_4386083_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 569.0
PYH2_k127_4386083_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 527.0
PYH2_k127_4386083_4 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 299.0
PYH2_k127_4386083_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001655 290.0
PYH2_k127_4386083_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006731 262.0
PYH2_k127_4386083_7 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000001942 205.0
PYH2_k127_4386083_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000009982 169.0
PYH2_k127_4386083_9 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.000000000004794 68.0
PYH2_k127_4395675_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.918e-205 649.0
PYH2_k127_4395675_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 289.0
PYH2_k127_4395675_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000001862 122.0
PYH2_k127_4395675_3 Transmembrane anti-sigma factor - - - 0.00000000001573 67.0
PYH2_k127_4395675_4 Belongs to the anti-sigma-factor antagonist family - - - 0.00000009362 55.0
PYH2_k127_444632_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 533.0
PYH2_k127_444632_1 Preprotein translocase subunit TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 234.0
PYH2_k127_444632_2 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000000008918 214.0
PYH2_k127_444632_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000008285 196.0
PYH2_k127_444632_4 Dioxygenase - - - 0.0000000000000000000000000000000005312 134.0
PYH2_k127_444632_5 (Lipo)protein - - - 0.000000000000005126 85.0
PYH2_k127_4455196_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.003e-241 754.0
PYH2_k127_4455196_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 548.0
PYH2_k127_4455196_2 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.0000000000000000000000008518 105.0
PYH2_k127_4455196_3 Psort location CytoplasmicMembrane, score K03558 - - 0.00008226 45.0
PYH2_k127_4457690_0 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000454 278.0
PYH2_k127_4457690_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000046 271.0
PYH2_k127_4457690_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
PYH2_k127_4457690_3 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000006552 214.0
PYH2_k127_4478467_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 2.667e-295 910.0
PYH2_k127_4478467_1 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 453.0
PYH2_k127_4478467_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000009248 160.0
PYH2_k127_4480909_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 6.272e-199 629.0
PYH2_k127_4480909_1 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 315.0
PYH2_k127_448692_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 381.0
PYH2_k127_448692_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000007788 107.0
PYH2_k127_4489943_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000008822 130.0
PYH2_k127_4489943_1 Tetratricopeptide repeat - - - 0.00000000008139 73.0
PYH2_k127_4495537_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
PYH2_k127_4495537_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000003081 250.0
PYH2_k127_4495537_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000002957 234.0
PYH2_k127_4495537_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000001736 158.0
PYH2_k127_4495537_4 rieske 2fe-2s - - - 0.0000000000000000000000000000001702 132.0
PYH2_k127_4497254_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 426.0
PYH2_k127_4497254_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 352.0
PYH2_k127_4497254_2 Dodecin K09165 - - 0.000000000000000000005875 96.0
PYH2_k127_4497254_3 Competence protein ComEC K02238 - - 0.0004362 43.0
PYH2_k127_449956_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 346.0
PYH2_k127_449956_1 - - - - 0.00000000000000000000000000000000000000000000000315 184.0
PYH2_k127_449956_2 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000003353 179.0
PYH2_k127_449956_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000004045 115.0
PYH2_k127_449956_4 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.0000000000000000000001739 98.0
PYH2_k127_4509838_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2410.0
PYH2_k127_4509838_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 5.693e-295 934.0
PYH2_k127_4509838_2 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000004881 197.0
PYH2_k127_4509838_3 Glucose / Sorbosone dehydrogenase K00117,K21430 - 1.1.5.2 0.000000002153 70.0
PYH2_k127_4560391_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 541.0
PYH2_k127_4560391_1 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 462.0
PYH2_k127_4560391_2 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 447.0
PYH2_k127_4560391_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
PYH2_k127_4560391_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000324 95.0
PYH2_k127_4562048_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.694e-241 751.0
PYH2_k127_4562048_1 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 329.0
PYH2_k127_4562048_2 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 326.0
PYH2_k127_4562048_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001855 274.0
PYH2_k127_4562048_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000004091 220.0
PYH2_k127_4562048_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000006878 85.0
PYH2_k127_4566043_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 6.33e-209 655.0
PYH2_k127_4566043_1 Glutaredoxin K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 326.0
PYH2_k127_4566043_2 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001373 289.0
PYH2_k127_4566043_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002638 259.0
PYH2_k127_4566043_4 stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000009941 153.0
PYH2_k127_4566043_5 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain K04691,K04772 - - 0.000000002484 59.0
PYH2_k127_4579005_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 453.0
PYH2_k127_4579005_1 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004538 261.0
PYH2_k127_4579005_2 Solute carrier family 35 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001114 254.0
PYH2_k127_4585950_0 Sulfatase K01130 - 3.1.6.1 4.522e-271 844.0
PYH2_k127_4585950_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.781e-266 827.0
PYH2_k127_4585950_10 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000007603 199.0
PYH2_k127_4585950_11 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000005922 185.0
PYH2_k127_4585950_2 enoyl-CoA hydratase K15513 - 4.1.2.44 2.198e-247 787.0
PYH2_k127_4585950_3 Poly-beta-hydroxybutyrate K03821 - - 1.304e-243 765.0
PYH2_k127_4585950_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.02e-242 757.0
PYH2_k127_4585950_5 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.841e-226 711.0
PYH2_k127_4585950_6 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
PYH2_k127_4585950_7 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001906 254.0
PYH2_k127_4585950_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
PYH2_k127_4585950_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000005831 231.0
PYH2_k127_4598062_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 592.0
PYH2_k127_4598062_1 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 535.0
PYH2_k127_4598062_2 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 421.0
PYH2_k127_4598062_3 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
PYH2_k127_4598062_4 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000021 113.0
PYH2_k127_4598512_0 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 496.0
PYH2_k127_4598512_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 467.0
PYH2_k127_4598512_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 346.0
PYH2_k127_4598512_4 Pfam Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000004138 143.0
PYH2_k127_4598512_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000001417 95.0
PYH2_k127_4656873_0 Exopolysaccharide biosynthesis protein YbjH - - - 1.977e-215 701.0
PYH2_k127_4656873_1 MORN repeat-containing protein - - - 0.00000000000003818 84.0
PYH2_k127_4665963_0 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 571.0
PYH2_k127_4665963_1 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000001809 114.0
PYH2_k127_4716473_0 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
PYH2_k127_4716473_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000007887 254.0
PYH2_k127_4716473_2 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000001753 169.0
PYH2_k127_4716473_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000004556 113.0
PYH2_k127_4723298_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1186.0
PYH2_k127_4723298_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 515.0
PYH2_k127_4723298_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
PYH2_k127_4723298_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000003678 213.0
PYH2_k127_4723298_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000001062 136.0
PYH2_k127_4723298_5 Cytochrome c, class I - - - 0.000000000000000000000001477 107.0
PYH2_k127_4733883_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.41e-300 934.0
PYH2_k127_4733883_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 3.101e-296 918.0
PYH2_k127_4733883_10 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 415.0
PYH2_k127_4733883_11 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 368.0
PYH2_k127_4733883_12 Inner membrane protein involved in colicin E2 resistance K06143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 367.0
PYH2_k127_4733883_13 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 335.0
PYH2_k127_4733883_14 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 325.0
PYH2_k127_4733883_15 Pfam:AmoA K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001087 276.0
PYH2_k127_4733883_16 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
PYH2_k127_4733883_17 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH2_k127_4733883_18 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
PYH2_k127_4733883_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000008721 195.0
PYH2_k127_4733883_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.03e-277 857.0
PYH2_k127_4733883_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000007954 179.0
PYH2_k127_4733883_21 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000006601 184.0
PYH2_k127_4733883_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000003036 156.0
PYH2_k127_4733883_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000007629 143.0
PYH2_k127_4733883_25 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000113 115.0
PYH2_k127_4733883_26 ATP synthase I chain K02116 - - 0.000000000000000003197 93.0
PYH2_k127_4733883_27 Histidine kinase - - - 0.000000000103 72.0
PYH2_k127_4733883_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.824e-259 804.0
PYH2_k127_4733883_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.534e-199 630.0
PYH2_k127_4733883_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 565.0
PYH2_k127_4733883_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 477.0
PYH2_k127_4733883_7 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 459.0
PYH2_k127_4733883_8 Domain of unknown function (DUF4347) K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 469.0
PYH2_k127_4733883_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 428.0
PYH2_k127_4747435_0 Ammonium transporter K03320 - - 9.111e-226 708.0
PYH2_k127_4747435_1 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
PYH2_k127_4747435_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000005863 197.0
PYH2_k127_4747435_3 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000005215 162.0
PYH2_k127_4747435_4 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000231 103.0
PYH2_k127_4756749_0 in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 9.29e-218 689.0
PYH2_k127_4756749_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 404.0
PYH2_k127_4756749_2 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000009484 87.0
PYH2_k127_4791139_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.396e-242 758.0
PYH2_k127_4791139_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000281 242.0
PYH2_k127_4791139_2 Stress-induced protein - - - 0.00000000000000000000000000000000000007519 144.0
PYH2_k127_4791139_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000002457 106.0
PYH2_k127_4797056_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.542e-225 719.0
PYH2_k127_4797056_1 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000002903 203.0
PYH2_k127_4797056_2 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000000000000003211 126.0
PYH2_k127_4797056_3 glycosyl transferase group 1 - - - 0.0000000000000008637 82.0
PYH2_k127_4798564_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.008e-201 655.0
PYH2_k127_4798564_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 531.0
PYH2_k127_4798564_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000004833 184.0
PYH2_k127_4798564_3 Cyclophilin-like K09143 - - 0.00000000000000000000000000001804 132.0
PYH2_k127_4798564_4 KTSC domain - - - 0.0000003248 60.0
PYH2_k127_4798564_5 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000001171 51.0
PYH2_k127_4798564_6 17 kDa surface antigen - - - 0.0004861 48.0
PYH2_k127_4806941_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1176.0
PYH2_k127_4806941_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 257.0
PYH2_k127_4806941_2 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000164 228.0
PYH2_k127_4806941_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
PYH2_k127_4806941_4 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000004308 192.0
PYH2_k127_4806941_5 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000615 193.0
PYH2_k127_4806941_6 dehydratase - - - 0.000000000000000000000000000000000000000000000001487 185.0
PYH2_k127_4806941_7 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000005106 143.0
PYH2_k127_4806941_8 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000007857 139.0
PYH2_k127_4806941_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000004974 84.0
PYH2_k127_4834632_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 342.0
PYH2_k127_4834632_1 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000006646 120.0
PYH2_k127_4834632_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000003536 90.0
PYH2_k127_4836867_0 aldo keto reductase family K07079 - - 0.000000000000000000000000000002014 135.0
PYH2_k127_4836867_1 - - - - 0.0000000000000001535 90.0
PYH2_k127_484665_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000385 286.0
PYH2_k127_484665_1 serine threonine protein kinase K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000005782 209.0
PYH2_k127_484665_2 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0000000000000000006938 87.0
PYH2_k127_484665_3 (Hpt) domain - - - 0.000000000000000003832 87.0
PYH2_k127_484665_4 COG2206 HD-GYP domain - - - 0.0009509 49.0
PYH2_k127_4881987_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 366.0
PYH2_k127_4881987_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 308.0
PYH2_k127_4881987_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001929 287.0
PYH2_k127_4881987_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003586 259.0
PYH2_k127_4881987_4 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000001532 157.0
PYH2_k127_4881987_5 branched-chain amino acid K01995 - - 0.00000000000000000000000000001043 134.0
PYH2_k127_4898986_0 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 300.0
PYH2_k127_4898986_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
PYH2_k127_4898986_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000005326 149.0
PYH2_k127_4910126_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1234.0
PYH2_k127_4910126_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.563e-215 673.0
PYH2_k127_4910126_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 349.0
PYH2_k127_4910126_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000001999 142.0
PYH2_k127_4910126_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000005214 126.0
PYH2_k127_4910126_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000006228 114.0
PYH2_k127_4910126_6 - - - - 0.0000000000000008718 79.0
PYH2_k127_4918112_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.751e-244 764.0
PYH2_k127_4918112_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 4.194e-228 713.0
PYH2_k127_4933736_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 565.0
PYH2_k127_4933736_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 459.0
PYH2_k127_4933736_2 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 332.0
PYH2_k127_4933736_3 PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ - - - 0.00000000000000000000000000000000000005792 149.0
PYH2_k127_4933736_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000003887 135.0
PYH2_k127_4933736_6 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000009225 57.0
PYH2_k127_4981325_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1495.0
PYH2_k127_4981325_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001068 240.0
PYH2_k127_4981325_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000003262 207.0
PYH2_k127_4981325_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000005152 193.0
PYH2_k127_4981325_4 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000001673 183.0
PYH2_k127_4981679_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.078e-276 854.0
PYH2_k127_4981679_1 arylsulfatase A K01130 - 3.1.6.1 1.242e-270 840.0
PYH2_k127_4981679_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.619e-237 742.0
PYH2_k127_4981679_3 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 419.0
PYH2_k127_4981679_4 PAP2 superfamily K19803 - 2.7.4.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003049 303.0
PYH2_k127_4981679_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000002233 220.0
PYH2_k127_4981679_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000001322 203.0
PYH2_k127_4981679_7 Tetratricopeptide repeat - - - 0.00000000000000000005683 93.0
PYH2_k127_5000076_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1437.0
PYH2_k127_5000076_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 1.889e-259 816.0
PYH2_k127_5000076_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000003755 78.0
PYH2_k127_5000076_2 ABC transporter K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 411.0
PYH2_k127_5000076_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 412.0
PYH2_k127_5000076_4 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 375.0
PYH2_k127_5000076_5 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 337.0
PYH2_k127_5000076_6 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
PYH2_k127_5000076_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000002629 195.0
PYH2_k127_5000076_8 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000001848 186.0
PYH2_k127_5000076_9 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000008014 148.0
PYH2_k127_5009224_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1241.0
PYH2_k127_5009224_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 419.0
PYH2_k127_5009224_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 331.0
PYH2_k127_5009224_3 Outer membrane efflux protein K18139 - - 0.00000000001597 66.0
PYH2_k127_5032531_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 405.0
PYH2_k127_5032531_1 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 302.0
PYH2_k127_5032531_2 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000006075 195.0
PYH2_k127_5032531_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.000000002574 58.0
PYH2_k127_5037345_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 475.0
PYH2_k127_5037345_1 Universal stress protein family - - - 0.0000000000000000000000000000731 122.0
PYH2_k127_5068947_0 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 385.0
PYH2_k127_5068947_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 307.0
PYH2_k127_5068947_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 291.0
PYH2_k127_5068947_3 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000022 284.0
PYH2_k127_5068947_4 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 263.0
PYH2_k127_5068947_5 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000001335 164.0
PYH2_k127_5068947_6 - - - - 0.0001975 48.0
PYH2_k127_5106533_0 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 610.0
PYH2_k127_5106533_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 592.0
PYH2_k127_5106533_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000001576 74.0
PYH2_k127_5136441_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 8.351e-232 734.0
PYH2_k127_5136441_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.177e-231 739.0
PYH2_k127_5136441_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000002446 118.0
PYH2_k127_5149710_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.336e-313 970.0
PYH2_k127_5149710_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
PYH2_k127_5149710_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000002113 227.0
PYH2_k127_5149710_3 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000001337 176.0
PYH2_k127_5149710_4 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000147 165.0
PYH2_k127_5149710_5 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000002105 149.0
PYH2_k127_5149710_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000002595 140.0
PYH2_k127_5170624_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 374.0
PYH2_k127_5170624_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 368.0
PYH2_k127_5170624_2 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 358.0
PYH2_k127_5170624_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000004474 72.0
PYH2_k127_5171277_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.204e-314 991.0
PYH2_k127_5174439_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.38e-235 738.0
PYH2_k127_5174439_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 496.0
PYH2_k127_5174439_2 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 490.0
PYH2_k127_5174439_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 466.0
PYH2_k127_5174439_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 449.0
PYH2_k127_5174439_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 434.0
PYH2_k127_5174439_6 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 352.0
PYH2_k127_5201656_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 604.0
PYH2_k127_5201656_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 329.0
PYH2_k127_5201656_2 HlyD membrane-fusion protein of T1SS - - - 0.000000000000000000000000001323 119.0
PYH2_k127_5201720_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 610.0
PYH2_k127_5201720_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
PYH2_k127_5201720_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000026 213.0
PYH2_k127_5201720_3 cytochrome - - - 0.000000000000006327 82.0
PYH2_k127_5201720_4 - - - - 0.0003577 53.0
PYH2_k127_5202080_0 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 498.0
PYH2_k127_5202080_1 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 399.0
PYH2_k127_5202080_2 COG4597 ABC-type amino acid transport system, permease component K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 297.0
PYH2_k127_5202080_3 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002798 257.0
PYH2_k127_5202080_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000001318 71.0
PYH2_k127_5205008_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
PYH2_k127_5205008_1 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000002218 171.0
PYH2_k127_5205008_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000094 74.0
PYH2_k127_5215515_0 Fumarate reductase flavoprotein C-term - - - 2.849e-200 633.0
PYH2_k127_5215515_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 501.0
PYH2_k127_5215515_2 C4-dicarboxylate transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 497.0
PYH2_k127_5215515_3 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 428.0
PYH2_k127_5215515_4 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 419.0
PYH2_k127_5215515_5 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000001003 153.0
PYH2_k127_5226923_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.926e-307 959.0
PYH2_k127_5226923_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
PYH2_k127_5226923_2 Hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 419.0
PYH2_k127_5226923_3 Transcriptional regulator crp fnr family K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
PYH2_k127_5226923_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
PYH2_k127_5226923_5 FecR protein - - - 0.0000000000000000000000000000000000000000000000006857 183.0
PYH2_k127_5226923_6 AAA C-terminal domain K07478 - - 0.00000000000005085 72.0
PYH2_k127_5232948_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
PYH2_k127_5232948_1 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000007935 222.0
PYH2_k127_5232948_2 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000008724 203.0
PYH2_k127_5232948_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000006615 98.0
PYH2_k127_5244141_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 504.0
PYH2_k127_5244141_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000009696 193.0
PYH2_k127_5244141_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000415 93.0
PYH2_k127_5271737_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 582.0
PYH2_k127_5271737_1 Cysteine rich repeat K06816 GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026 - 0.00000001409 63.0
PYH2_k127_5273713_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.933e-237 738.0
PYH2_k127_5273713_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 270.0
PYH2_k127_5273713_10 - - - - 0.00001415 57.0
PYH2_k127_5273713_2 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001859 259.0
PYH2_k127_5273713_3 Glyoxalase bleomycin resistance - - - 0.00000000000000000000000000000000000000000000000000001838 190.0
PYH2_k127_5273713_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000002346 186.0
PYH2_k127_5273713_5 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000003205 187.0
PYH2_k127_5273713_6 response regulator - - - 0.00000000000000000000000000000000000000001188 163.0
PYH2_k127_5273713_7 Cupin domain - - - 0.000000000000000000000000000000000001566 145.0
PYH2_k127_5273713_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000005488 143.0
PYH2_k127_5273713_9 PFAM ribosomal protein L31 K02909 - - 0.00000000000000000000000000002571 119.0
PYH2_k127_5289281_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 613.0
PYH2_k127_5289281_1 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 340.0
PYH2_k127_5289281_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 306.0
PYH2_k127_5289281_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 280.0
PYH2_k127_5289281_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000003281 260.0
PYH2_k127_5289281_5 Sh3 type 3 domain protein - - - 0.0000000007454 71.0
PYH2_k127_5289616_0 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 293.0
PYH2_k127_5289616_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
PYH2_k127_5289616_2 MOFRL family - - - 0.0000000000000000000000000003887 116.0
PYH2_k127_5291946_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 612.0
PYH2_k127_5291946_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 336.0
PYH2_k127_5292365_0 Aminotransferase K14261 - - 4.445e-221 689.0
PYH2_k127_5292365_1 Cysteine-rich domain - - - 1.384e-220 691.0
PYH2_k127_5292365_2 homoserine dehydrogenase K00003 - 1.1.1.3 1.177e-200 653.0
PYH2_k127_5292365_3 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 611.0
PYH2_k127_5292365_4 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 349.0
PYH2_k127_5292365_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000132 194.0
PYH2_k127_5292365_6 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000007202 155.0
PYH2_k127_5292365_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000007097 149.0
PYH2_k127_5292365_8 Vibrio cholerae RfbT protein - - - 0.00000000000000000004083 102.0
PYH2_k127_5313160_0 polysaccharide export protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 582.0
PYH2_k127_5314600_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1588.0
PYH2_k127_5314600_1 transcriptional Regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002987 249.0
PYH2_k127_5324000_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1234.0
PYH2_k127_5324000_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 6.035e-195 617.0
PYH2_k127_5324000_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 552.0
PYH2_k127_5324000_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000001688 199.0
PYH2_k127_5325678_0 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 565.0
PYH2_k127_5325678_1 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000001237 216.0
PYH2_k127_5325678_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000001105 122.0
PYH2_k127_5325678_3 mechanosensitive K05802 - - 0.000000000000000000000001606 104.0
PYH2_k127_5325678_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001369 95.0
PYH2_k127_5330821_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 2.399e-209 672.0
PYH2_k127_5330821_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 511.0
PYH2_k127_5330821_2 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 456.0
PYH2_k127_5330821_3 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 324.0
PYH2_k127_5330821_4 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000001184 207.0
PYH2_k127_5330821_5 acid transport system permease K09970 - - 0.000002438 49.0
PYH2_k127_5331221_0 Hydantoinase/oxoprolinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005898 266.0
PYH2_k127_5331221_1 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005523 247.0
PYH2_k127_5331221_2 - - - - 0.000000000000000000000003229 111.0
PYH2_k127_5331221_3 LTXXQ motif family protein - - - 0.000000000000000000003969 98.0
PYH2_k127_5331221_4 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000004266 58.0
PYH2_k127_5346398_0 AMP-binding enzyme K12508 - 6.2.1.34 7.108e-220 702.0
PYH2_k127_5346398_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 365.0
PYH2_k127_5346398_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 359.0
PYH2_k127_5346398_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000001466 151.0
PYH2_k127_5346398_4 Transcriptional regulator - - - 0.000000000000000000000000000000000008523 140.0
PYH2_k127_5355099_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 423.0
PYH2_k127_5355099_1 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 379.0
PYH2_k127_5355099_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
PYH2_k127_5355099_3 FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 357.0
PYH2_k127_5355099_4 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 324.0
PYH2_k127_5355099_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 314.0
PYH2_k127_5355099_6 Hsp33 protein K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
PYH2_k127_5355099_7 Protein of unknown function (DUF3467) - - - 0.0000000000007559 69.0
PYH2_k127_5355157_0 Peptidase M50 K16922 - - 1.314e-196 640.0
PYH2_k127_5355157_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 483.0
PYH2_k127_5355157_2 Protein of unknown function (DUF3467) - - - 0.000000000009657 66.0
PYH2_k127_5378694_0 Belongs to the IlvD Edd family - - - 8.887e-284 884.0
PYH2_k127_5378694_1 Protein of unknown function, DUF255 K06888 - - 6.286e-249 790.0
PYH2_k127_5378694_10 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
PYH2_k127_5378694_11 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 248.0
PYH2_k127_5378694_12 PFAM Bacterial protein of - - - 0.0000000000000000000000000000000000000000000000000000000000001738 218.0
PYH2_k127_5378694_13 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000002244 152.0
PYH2_k127_5378694_14 4Fe-4S dicluster domain - - - 0.0000000111 55.0
PYH2_k127_5378694_2 PFAM AMP-dependent synthetase and ligase - - - 5.595e-230 722.0
PYH2_k127_5378694_3 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 483.0
PYH2_k127_5378694_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 491.0
PYH2_k127_5378694_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 450.0
PYH2_k127_5378694_6 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 426.0
PYH2_k127_5378694_7 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 383.0
PYH2_k127_5378694_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 369.0
PYH2_k127_5378694_9 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 374.0
PYH2_k127_5399642_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 499.0
PYH2_k127_5399642_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 422.0
PYH2_k127_5399642_10 Histidine kinase-like ATPase domain - - - 0.000000000000000009214 92.0
PYH2_k127_5399642_11 STAS domain - - - 0.00000000004635 68.0
PYH2_k127_5399642_12 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000001243 62.0
PYH2_k127_5399642_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 411.0
PYH2_k127_5399642_3 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 376.0
PYH2_k127_5399642_4 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 342.0
PYH2_k127_5399642_5 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 329.0
PYH2_k127_5399642_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 265.0
PYH2_k127_5399642_7 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007561 197.0
PYH2_k127_5399642_8 OmpA family - - - 0.000000000000000000000000000000000000000008129 160.0
PYH2_k127_5399642_9 FecR protein - - - 0.000000000000000000000000000000000000002213 151.0
PYH2_k127_5406027_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 471.0
PYH2_k127_5406027_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 428.0
PYH2_k127_5406027_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 410.0
PYH2_k127_5406027_3 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
PYH2_k127_5406027_4 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 356.0
PYH2_k127_5406027_5 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 0.00002164 49.0
PYH2_k127_5407764_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1388.0
PYH2_k127_5407764_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 9.212e-258 827.0
PYH2_k127_5407764_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 534.0
PYH2_k127_5407764_3 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 413.0
PYH2_k127_5407764_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 356.0
PYH2_k127_5407764_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 295.0
PYH2_k127_5407764_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000002607 167.0
PYH2_k127_5407764_7 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000004625 66.0
PYH2_k127_5419964_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 529.0
PYH2_k127_5419964_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000005174 221.0
PYH2_k127_5419964_2 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
PYH2_k127_5419964_3 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
PYH2_k127_5419964_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000002794 210.0
PYH2_k127_5419964_5 - - - - 0.0000000000000000000000000000000000000000000000005581 189.0
PYH2_k127_5419964_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH2_k127_5419964_7 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000009594 148.0
PYH2_k127_5419964_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000002244 122.0
PYH2_k127_5419964_9 ABC transporter transmembrane region K02021 - - 0.00000000000000000000000427 105.0
PYH2_k127_5427938_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 5.823e-276 859.0
PYH2_k127_5427938_1 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 406.0
PYH2_k127_5427938_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 336.0
PYH2_k127_5427938_3 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001057 259.0
PYH2_k127_5427938_4 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000008184 168.0
PYH2_k127_5436623_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1073.0
PYH2_k127_5436623_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.221e-214 677.0
PYH2_k127_5436623_2 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 456.0
PYH2_k127_5436623_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003608 241.0
PYH2_k127_5436623_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000003783 192.0
PYH2_k127_5436623_5 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001018 74.0
PYH2_k127_5461735_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
PYH2_k127_5461735_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 402.0
PYH2_k127_5461735_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000003241 137.0
PYH2_k127_5461735_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.00000000000001057 82.0
PYH2_k127_5463457_0 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 428.0
PYH2_k127_5463457_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 358.0
PYH2_k127_5463457_2 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 313.0
PYH2_k127_5463457_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 250.0
PYH2_k127_5463457_4 Phasin protein - - - 0.00000000000000000000000000000000000000000000000001548 186.0
PYH2_k127_5463457_5 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000003161 172.0
PYH2_k127_5463457_6 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000112 71.0
PYH2_k127_5471284_0 PFAM AMP-dependent synthetase and ligase K12508 - 6.2.1.34 2.149e-198 631.0
PYH2_k127_5471284_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 415.0
PYH2_k127_5473123_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.297e-230 726.0
PYH2_k127_5473123_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 616.0
PYH2_k127_5473123_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 442.0
PYH2_k127_5473123_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000004485 203.0
PYH2_k127_5473123_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000000002511 100.0
PYH2_k127_5473123_5 enzyme of heme biosynthesis K02498 - - 0.000004399 49.0
PYH2_k127_5479885_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
PYH2_k127_5479885_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000111 238.0
PYH2_k127_5479885_2 - - - - 0.000000000000000000000000000000000000001588 153.0
PYH2_k127_5479885_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000002747 58.0
PYH2_k127_5487139_0 Amidohydrolase family - - - 4.044e-232 730.0
PYH2_k127_5487139_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 361.0
PYH2_k127_5487139_2 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009521 263.0
PYH2_k127_5487139_3 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 249.0
PYH2_k127_5487139_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
PYH2_k127_5487139_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000006868 188.0
PYH2_k127_5509004_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 572.0
PYH2_k127_5509004_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 432.0
PYH2_k127_5509004_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000004175 116.0
PYH2_k127_5512853_0 Ferrous iron transport protein B K04759 - - 4.031e-221 705.0
PYH2_k127_5512853_1 OPT oligopeptide transporter protein - - - 1.662e-200 640.0
PYH2_k127_5512853_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 285.0
PYH2_k127_5512853_3 Response regulator of the LytR AlgR family K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004888 253.0
PYH2_k127_5512853_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008121 250.0
PYH2_k127_5512853_5 hydratase decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000059 203.0
PYH2_k127_5512853_6 Histidine kinase - - - 0.000000000000000000004598 103.0
PYH2_k127_5512853_7 NADPH quinone reductase K00344 - 1.6.5.5 0.00005964 49.0
PYH2_k127_5512853_8 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0001691 49.0
PYH2_k127_5520723_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.517e-242 759.0
PYH2_k127_5520723_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 1.576e-230 724.0
PYH2_k127_5520723_10 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000001139 212.0
PYH2_k127_5520723_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000008403 209.0
PYH2_k127_5520723_12 FecR protein - - - 0.000000000000000000000000000000000000000001708 166.0
PYH2_k127_5520723_13 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000001504 136.0
PYH2_k127_5520723_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000002129 137.0
PYH2_k127_5520723_15 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000002581 137.0
PYH2_k127_5520723_16 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000003526 84.0
PYH2_k127_5520723_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0003116 44.0
PYH2_k127_5520723_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.132e-198 627.0
PYH2_k127_5520723_3 Protein of unknown function (DUF1254) - - - 3.01e-196 614.0
PYH2_k127_5520723_4 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 545.0
PYH2_k127_5520723_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 433.0
PYH2_k127_5520723_6 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
PYH2_k127_5520723_7 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 365.0
PYH2_k127_5520723_8 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003541 293.0
PYH2_k127_5520723_9 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008511 261.0
PYH2_k127_5557556_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.7e-322 997.0
PYH2_k127_5557556_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000158 187.0
PYH2_k127_5557556_2 Cytochrome P460 - - - 0.00000000000000000000003405 110.0
PYH2_k127_5557556_3 cytochrome - - - 0.00000000000000008751 91.0
PYH2_k127_5573306_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.577e-280 872.0
PYH2_k127_5573306_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 288.0
PYH2_k127_5573306_2 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000004305 161.0
PYH2_k127_5573306_3 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000004707 135.0
PYH2_k127_5579885_0 Selenium-binding protein K17285 - - 5.204e-222 693.0
PYH2_k127_5579885_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 475.0
PYH2_k127_5593282_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.227e-246 773.0
PYH2_k127_5593282_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 492.0
PYH2_k127_5593282_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 471.0
PYH2_k127_5593282_3 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 431.0
PYH2_k127_5593282_4 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 365.0
PYH2_k127_5593282_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 310.0
PYH2_k127_5593282_6 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006857 261.0
PYH2_k127_5593282_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000302 225.0
PYH2_k127_5593282_8 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000007249 119.0
PYH2_k127_5593823_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 310.0
PYH2_k127_5593823_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000006084 246.0
PYH2_k127_5593823_2 - - - - 0.000000000000000000000000000002059 123.0
PYH2_k127_5593823_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001971 89.0
PYH2_k127_5593823_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000718 76.0
PYH2_k127_5626858_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 533.0
PYH2_k127_5626858_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 467.0
PYH2_k127_5626858_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
PYH2_k127_5626858_11 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000002874 166.0
PYH2_k127_5626858_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 451.0
PYH2_k127_5626858_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 435.0
PYH2_k127_5626858_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 420.0
PYH2_k127_5626858_5 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 415.0
PYH2_k127_5626858_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
PYH2_k127_5626858_7 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
PYH2_k127_5626858_8 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
PYH2_k127_5626858_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000266 286.0
PYH2_k127_5633513_0 Oxidoreductase - - - 2.452e-203 647.0
PYH2_k127_5633513_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000001837 191.0
PYH2_k127_5633513_2 Copper binding periplasmic protein CusF - - - 0.00000000000000000000000000001349 119.0
PYH2_k127_5644258_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 6.409e-265 898.0
PYH2_k127_5644258_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 9.262e-212 669.0
PYH2_k127_5644258_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009532 267.0
PYH2_k127_5644258_11 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006384 233.0
PYH2_k127_5644258_12 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
PYH2_k127_5644258_13 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000001184 207.0
PYH2_k127_5644258_14 dehydratase - - - 0.000000000000000000000000000000000000000000000000004008 185.0
PYH2_k127_5644258_15 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000000000000000000000000000001302 176.0
PYH2_k127_5644258_16 phosphorelay signal transduction system K11443 - - 0.000000000000000000000000000000000318 148.0
PYH2_k127_5644258_2 Receptor family ligand binding region - - - 3.226e-208 662.0
PYH2_k127_5644258_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 479.0
PYH2_k127_5644258_4 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 420.0
PYH2_k127_5644258_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 422.0
PYH2_k127_5644258_6 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 437.0
PYH2_k127_5644258_7 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH2_k127_5644258_8 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 350.0
PYH2_k127_5644258_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003758 284.0
PYH2_k127_5652290_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 325.0
PYH2_k127_5652290_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000003729 199.0
PYH2_k127_5652290_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000004468 213.0
PYH2_k127_5652290_3 Gaf domain K01768,K04769 - 4.6.1.1 0.00001306 57.0
PYH2_k127_5674746_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.624e-241 758.0
PYH2_k127_5674746_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 397.0
PYH2_k127_5674746_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 329.0
PYH2_k127_5674746_3 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000005445 211.0
PYH2_k127_5674746_4 prepilin-type N-terminal cleavage methylation K02456 - - 0.000000000000000000000000000000000000000000000000000000002178 203.0
PYH2_k127_5674746_5 prepilin-type N-terminal cleavage methylation K02456 - - 0.00000000000000000000000000000000000000000002763 166.0
PYH2_k127_5674746_6 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000000000000000000005165 166.0
PYH2_k127_5692684_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 523.0
PYH2_k127_5692684_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 368.0
PYH2_k127_5694552_0 GMC oxidoreductase K00108 - 1.1.99.1 7.666e-241 753.0
PYH2_k127_5694552_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.667e-208 677.0
PYH2_k127_5694552_10 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000004004 224.0
PYH2_k127_5694552_11 short-chain dehydrogenase - - - 0.00001061 54.0
PYH2_k127_5694552_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 1.749e-203 650.0
PYH2_k127_5694552_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 608.0
PYH2_k127_5694552_4 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 570.0
PYH2_k127_5694552_5 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 535.0
PYH2_k127_5694552_6 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 465.0
PYH2_k127_5694552_7 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 342.0
PYH2_k127_5694552_8 belongs to the CobB CobQ family K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 310.0
PYH2_k127_5694552_9 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
PYH2_k127_5695585_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 376.0
PYH2_k127_5695585_1 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 329.0
PYH2_k127_5695585_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000223 90.0
PYH2_k127_5725126_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.815e-294 911.0
PYH2_k127_5725126_1 cytochrome - - - 1.823e-239 750.0
PYH2_k127_5725126_2 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 513.0
PYH2_k127_5725126_3 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 334.0
PYH2_k127_5725126_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000002242 131.0
PYH2_k127_5725126_5 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000005046 123.0
PYH2_k127_5725126_6 Sterol-binding domain protein - - - 0.000000000000000000000003828 111.0
PYH2_k127_5725126_7 Uncharacterized conserved protein (DUF2249) - - - 0.000000382 52.0
PYH2_k127_5733798_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 4.491e-251 790.0
PYH2_k127_5733798_1 COG1180 Pyruvate-formate lyase-activating enzyme - - - 5.033e-233 728.0
PYH2_k127_5733798_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 571.0
PYH2_k127_5733798_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 511.0
PYH2_k127_5733798_4 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 347.0
PYH2_k127_5733798_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003794 287.0
PYH2_k127_5733798_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000039 196.0
PYH2_k127_5781118_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 505.0
PYH2_k127_5781118_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 370.0
PYH2_k127_5781118_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0002839 44.0
PYH2_k127_5788151_0 SNARE associated Golgi protein - - - 0.0 1024.0
PYH2_k127_5788151_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
PYH2_k127_5788151_2 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 301.0
PYH2_k127_5788151_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000002912 137.0
PYH2_k127_5788151_4 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000004191 71.0
PYH2_k127_5788151_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00006187 52.0
PYH2_k127_5812337_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000008253 225.0
PYH2_k127_5812337_1 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000004005 177.0
PYH2_k127_5812337_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000001325 103.0
PYH2_k127_5812337_3 FeS assembly protein IscX - - - 0.00000000000000000000001561 111.0
PYH2_k127_5816863_0 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 378.0
PYH2_k127_5816863_1 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000008346 204.0
PYH2_k127_582127_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 301.0
PYH2_k127_582127_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 293.0
PYH2_k127_582127_2 branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000001451 177.0
PYH2_k127_582127_3 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000006653 141.0
PYH2_k127_582127_4 Cupin 2, conserved barrel domain protein K19547 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897 5.3.3.19 0.0000000000000000000000003186 111.0
PYH2_k127_582127_5 OmpA-like transmembrane domain K03286 - - 0.0000000000000001257 88.0
PYH2_k127_582127_6 V4R - - - 0.00002662 48.0
PYH2_k127_5841760_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1248.0
PYH2_k127_5841760_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 549.0
PYH2_k127_5841760_2 [2Fe-2S] binding domain K03518,K04107 - 1.2.5.3,1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000006702 231.0
PYH2_k127_5841760_3 protein involved in response to NO K07234 - - 0.00000000000002888 86.0
PYH2_k127_5841760_4 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.0000598 46.0
PYH2_k127_5857135_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 1.647e-249 782.0
PYH2_k127_5857135_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.739e-197 623.0
PYH2_k127_5857135_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 441.0
PYH2_k127_5857135_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000003192 218.0
PYH2_k127_5857135_4 LysR substrate binding domain - - - 0.000000000000000000000003385 104.0
PYH2_k127_5887556_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1165.0
PYH2_k127_5887556_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 450.0
PYH2_k127_5887556_2 Chaperone protein TorD - - - 0.000000000000000000000000000001879 132.0
PYH2_k127_5887556_3 - - - - 0.00000002863 58.0
PYH2_k127_5907473_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1455.0
PYH2_k127_5907473_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 483.0
PYH2_k127_5907473_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 394.0
PYH2_k127_5907473_3 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000007227 152.0
PYH2_k127_5907473_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000001422 124.0
PYH2_k127_5907473_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.0000000000000000000000003556 107.0
PYH2_k127_5907473_6 Metal-sensitive transcriptional repressor - - - 0.000000000000001517 79.0
PYH2_k127_5974927_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 545.0
PYH2_k127_5974927_1 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 405.0
PYH2_k127_6035555_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 432.0
PYH2_k127_6035555_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 366.0
PYH2_k127_6035555_2 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 357.0
PYH2_k127_6035555_3 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000004646 200.0
PYH2_k127_6035555_4 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000001996 53.0
PYH2_k127_6063264_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.12e-279 869.0
PYH2_k127_6063264_1 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.000003394 49.0
PYH2_k127_6075364_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 461.0
PYH2_k127_6075364_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 424.0
PYH2_k127_6075364_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 400.0
PYH2_k127_6075364_3 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
PYH2_k127_6075364_4 SapC - - - 0.00000000000000000000000000000000000000005398 160.0
PYH2_k127_6075364_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000002222 109.0
PYH2_k127_6075364_6 - - - - 0.00000000000000000003166 92.0
PYH2_k127_6075364_7 - - - - 0.0000000000000001313 81.0
PYH2_k127_6111906_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1178.0
PYH2_k127_6111906_1 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000005935 208.0
PYH2_k127_6118031_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1465.0
PYH2_k127_6118031_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 649.0
PYH2_k127_6118031_2 Ami_2 K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000002106 231.0
PYH2_k127_6118031_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000006402 151.0
PYH2_k127_6118031_4 response regulator K02667 - - 0.000000000000001066 78.0
PYH2_k127_6118031_5 Protein of unknown function (DUF2442) - - - 0.0000000001388 64.0
PYH2_k127_6118031_6 Histone H1-like nucleoprotein HC2 K11275 - - 0.0000002959 56.0
PYH2_k127_6136006_0 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 403.0
PYH2_k127_6136006_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 392.0
PYH2_k127_6136006_2 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000004623 215.0
PYH2_k127_6136006_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000004671 151.0
PYH2_k127_6136006_4 TspO MBR family protein K05770 - - 0.00000000000000000000000000000000006926 141.0
PYH2_k127_6136006_5 Bacterial transcriptional regulator - - - 0.000000000000000000000000001194 115.0
PYH2_k127_6136006_6 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000003611 59.0
PYH2_k127_6161757_0 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 431.0
PYH2_k127_6161757_1 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 347.0
PYH2_k127_6173267_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 551.0
PYH2_k127_6173267_1 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001157 284.0
PYH2_k127_6173267_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000207 114.0
PYH2_k127_6179206_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 557.0
PYH2_k127_6179206_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 389.0
PYH2_k127_6179206_10 6-phosphogluconolactonase activity - - - 0.00000000003137 77.0
PYH2_k127_6179206_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
PYH2_k127_6179206_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 267.0
PYH2_k127_6179206_4 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000005868 250.0
PYH2_k127_6179206_5 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001645 245.0
PYH2_k127_6179206_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000002062 189.0
PYH2_k127_6179206_7 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000002155 190.0
PYH2_k127_6179206_8 OmpA family K03286 - - 0.000000000000000000000000000000000000337 144.0
PYH2_k127_6179206_9 Domain of unknown function (DUF4347) - - - 0.00000000000000008941 95.0
PYH2_k127_6183314_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 376.0
PYH2_k127_6183314_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000002283 201.0
PYH2_k127_6183314_2 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000003922 104.0
PYH2_k127_6184289_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 475.0
PYH2_k127_6184289_1 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000002008 199.0
PYH2_k127_6184289_2 Beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000001668 165.0
PYH2_k127_6184289_3 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001542 134.0
PYH2_k127_6194683_0 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 434.0
PYH2_k127_6194683_1 cytochrome - - - 0.0000000000000003589 93.0
PYH2_k127_6194683_2 PFAM Phosphoglycerate mutase - - - 0.0000000000000005579 79.0
PYH2_k127_6194683_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000002142 59.0
PYH2_k127_6198472_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 347.0
PYH2_k127_6198472_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 293.0
PYH2_k127_6202516_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 3.289e-216 677.0
PYH2_k127_6202516_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 537.0
PYH2_k127_6202516_2 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 0.0003245 43.0
PYH2_k127_6211711_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.519e-312 964.0
PYH2_k127_6211711_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 601.0
PYH2_k127_6211711_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
PYH2_k127_6211711_3 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005277 268.0
PYH2_k127_6211711_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
PYH2_k127_6211711_5 Domain of unknown function (DUF4845) - - - 0.00000000000001056 86.0
PYH2_k127_6230886_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.093e-211 663.0
PYH2_k127_6230886_1 Phenylacetic acid degradation protein PaaY K02617,K08279 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001578 257.0
PYH2_k127_6230886_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.000000000000000000000000000000000000000000000000000002155 214.0
PYH2_k127_623450_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.578e-197 624.0
PYH2_k127_623450_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 447.0
PYH2_k127_623450_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 344.0
PYH2_k127_623450_3 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
PYH2_k127_623450_4 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000003411 210.0
PYH2_k127_623450_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000001978 199.0
PYH2_k127_623450_6 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000004932 201.0
PYH2_k127_623450_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004986 153.0
PYH2_k127_623450_8 Putative zinc-finger - - - 0.00000003771 58.0
PYH2_k127_6251951_0 CoA-binding domain protein K09181 - - 1.118e-197 627.0
PYH2_k127_6251951_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 526.0
PYH2_k127_6251951_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 503.0
PYH2_k127_6251951_3 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 493.0
PYH2_k127_6251951_4 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 379.0
PYH2_k127_6251951_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002176 277.0
PYH2_k127_6251951_6 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000485 251.0
PYH2_k127_6251951_7 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000001198 140.0
PYH2_k127_6306397_0 Patatin-like phospholipase K07001 - - 5.342e-253 796.0
PYH2_k127_6306397_1 Glutathione S-transferase, C-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000002327 234.0
PYH2_k127_6306397_2 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000001803 160.0
PYH2_k127_632144_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.057e-209 665.0
PYH2_k127_632144_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 540.0
PYH2_k127_6338023_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 463.0
PYH2_k127_6338023_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 436.0
PYH2_k127_6338023_2 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 331.0
PYH2_k127_6338023_3 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 348.0
PYH2_k127_6338023_4 dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
PYH2_k127_6338023_5 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
PYH2_k127_6338023_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
PYH2_k127_6358277_0 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 420.0
PYH2_k127_6358277_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 357.0
PYH2_k127_6358277_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 330.0
PYH2_k127_6358277_3 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000009292 126.0
PYH2_k127_6377473_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 538.0
PYH2_k127_6377473_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000159 287.0
PYH2_k127_6377473_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000001772 182.0
PYH2_k127_639499_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.0 1067.0
PYH2_k127_639499_1 Amidohydrolase K10220 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 415.0
PYH2_k127_639499_2 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
PYH2_k127_639499_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000002943 201.0
PYH2_k127_6411928_0 - - - - 0.00000000000000000000000000000000000000000000000000438 199.0
PYH2_k127_6411928_1 Cytochrome c - - - 0.00000000000000000000000006548 124.0
PYH2_k127_6411928_2 - - - - 0.0000000000000000000005065 103.0
PYH2_k127_6411928_3 cytochrome - - - 0.000000000000000000002016 103.0
PYH2_k127_6411928_4 cytochrome c5 - - - 0.000000000000989 76.0
PYH2_k127_6411928_5 Cytochrome c - - - 0.000000000006586 75.0
PYH2_k127_6411928_6 Cytochrome c class - - - 0.0002803 54.0
PYH2_k127_643900_0 ABC transporter - - - 8.427e-241 755.0
PYH2_k127_643900_1 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 3.159e-220 709.0
PYH2_k127_643900_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 3.939e-195 621.0
PYH2_k127_643900_3 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 423.0
PYH2_k127_643900_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 391.0
PYH2_k127_643900_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 385.0
PYH2_k127_643900_6 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 346.0
PYH2_k127_643900_7 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 327.0
PYH2_k127_643900_8 hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006778 247.0
PYH2_k127_6465939_0 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 383.0
PYH2_k127_6465939_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
PYH2_k127_6465939_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000002297 207.0
PYH2_k127_6484368_0 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 372.0
PYH2_k127_6484368_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 317.0
PYH2_k127_6484368_2 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000009923 223.0
PYH2_k127_6484368_3 - - - - 0.0000000000000000000000004644 111.0
PYH2_k127_6498969_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.502e-204 644.0
PYH2_k127_6498969_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 497.0
PYH2_k127_6500060_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 382.0
PYH2_k127_6500060_1 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000000000000000006897 155.0
PYH2_k127_6500060_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000003059 144.0
PYH2_k127_6526951_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1207.0
PYH2_k127_6526951_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1052.0
PYH2_k127_6526951_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.615e-256 799.0
PYH2_k127_6526951_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000002408 203.0
PYH2_k127_6526951_4 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000002743 169.0
PYH2_k127_6526951_5 - - - - 0.00000000000000002085 83.0
PYH2_k127_6548918_0 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 489.0
PYH2_k127_6548918_1 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000002711 223.0
PYH2_k127_6548918_2 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000005202 211.0
PYH2_k127_6582351_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 541.0
PYH2_k127_6582351_1 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 377.0
PYH2_k127_6582351_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 334.0
PYH2_k127_6582351_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 334.0
PYH2_k127_6582351_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002836 255.0
PYH2_k127_6582351_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000001175 246.0
PYH2_k127_6582351_6 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000000000575 189.0
PYH2_k127_6582351_7 Acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000001582 137.0
PYH2_k127_6582351_8 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000003577 128.0
PYH2_k127_6582351_9 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000009077 83.0
PYH2_k127_6634321_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1510.0
PYH2_k127_6634321_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
PYH2_k127_6634321_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000002004 177.0
PYH2_k127_667530_0 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 3.016e-252 787.0
PYH2_k127_667530_1 NADH ubiquinone plastoquinone (Complex I) - - - 3.608e-224 711.0
PYH2_k127_667530_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 448.0
PYH2_k127_667530_3 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
PYH2_k127_6679843_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 457.0
PYH2_k127_6679843_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 409.0
PYH2_k127_6679843_2 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 297.0
PYH2_k127_6690288_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.443e-235 737.0
PYH2_k127_6690288_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.208e-221 710.0
PYH2_k127_6690288_10 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000003862 250.0
PYH2_k127_6690288_11 Tetratricopeptide repeat - - - 0.0000000000000000000002658 113.0
PYH2_k127_6690288_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 608.0
PYH2_k127_6690288_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 481.0
PYH2_k127_6690288_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 472.0
PYH2_k127_6690288_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 340.0
PYH2_k127_6690288_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 335.0
PYH2_k127_6690288_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 302.0
PYH2_k127_6690288_8 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 312.0
PYH2_k127_6690288_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006388 253.0
PYH2_k127_6728252_0 Belongs to the glutamate synthase family - - - 1.38e-244 763.0
PYH2_k127_6728252_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 508.0
PYH2_k127_6728252_2 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002827 283.0
PYH2_k127_6728252_3 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001553 218.0
PYH2_k127_6733972_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 5.733e-261 815.0
PYH2_k127_6733972_1 B-1 B cell differentiation K03634,K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 300.0
PYH2_k127_6733972_2 zinc protease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 290.0
PYH2_k127_6733972_3 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001068 269.0
PYH2_k127_6733972_4 Zinc-binding dehydrogenase K12957,K13953,K19961 - 1.1.1.1,1.1.1.258 0.00000000000000000000000000000000000000000000944 167.0
PYH2_k127_6733972_5 Alpha/beta hydrolase family - - - 0.0000000000317 65.0
PYH2_k127_6748788_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.52e-318 983.0
PYH2_k127_6748788_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 2.071e-310 983.0
PYH2_k127_6748788_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 602.0
PYH2_k127_6748788_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 435.0
PYH2_k127_6748788_4 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000001184 223.0
PYH2_k127_6748788_5 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000007525 152.0
PYH2_k127_6748788_6 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000239 126.0
PYH2_k127_6748788_7 Enoyl-CoA hydratase/isomerase - - - 0.000007556 53.0
PYH2_k127_6751598_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.363e-204 644.0
PYH2_k127_6751598_1 NMT1-like family - - - 0.000000000000000000000000000000000000000004093 160.0
PYH2_k127_6766366_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 404.0
PYH2_k127_6766366_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 357.0
PYH2_k127_6766366_2 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
PYH2_k127_6766366_3 signal sequence binding - - - 0.000000000000000000000000000000000000000000000002286 179.0
PYH2_k127_6766366_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000002463 141.0
PYH2_k127_6766366_5 SURF1-like protein K14998 - - 0.000000000000000009174 87.0
PYH2_k127_6790693_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 433.0
PYH2_k127_6790693_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 343.0
PYH2_k127_6790693_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000287 201.0
PYH2_k127_6790693_3 Small MutS-related domain - - - 0.00000000000000000000000000000000000000005605 154.0
PYH2_k127_6790693_4 Glycerophosphoryl diester phosphodiesterase family K01126 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008889,GO:0016787,GO:0016788,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0047389,GO:0047395 3.1.4.46 0.0000000000000000000000000000421 118.0
PYH2_k127_6793329_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
PYH2_k127_6793329_1 haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000002684 190.0
PYH2_k127_6793329_2 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000001042 178.0
PYH2_k127_6798116_0 type I secretion membrane fusion K02022,K12537 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 348.0
PYH2_k127_6798116_1 Type I secretion system K16299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003242 261.0
PYH2_k127_6835537_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1603.0
PYH2_k127_6835537_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1545.0
PYH2_k127_6835537_10 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 430.0
PYH2_k127_6835537_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 410.0
PYH2_k127_6835537_12 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 387.0
PYH2_k127_6835537_13 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 384.0
PYH2_k127_6835537_14 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 369.0
PYH2_k127_6835537_15 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 302.0
PYH2_k127_6835537_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 280.0
PYH2_k127_6835537_17 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
PYH2_k127_6835537_18 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000000000000001242 213.0
PYH2_k127_6835537_19 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000003291 162.0
PYH2_k127_6835537_2 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.564e-292 909.0
PYH2_k127_6835537_20 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000002625 117.0
PYH2_k127_6835537_21 Fe-S protein K06938 - - 0.0000000006856 66.0
PYH2_k127_6835537_22 Outer membrane efflux protein - - - 0.000000006457 64.0
PYH2_k127_6835537_3 Domain of unknown function (DUF4070) - - - 4.732e-219 688.0
PYH2_k127_6835537_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.321e-209 659.0
PYH2_k127_6835537_5 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 537.0
PYH2_k127_6835537_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 504.0
PYH2_k127_6835537_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 465.0
PYH2_k127_6835537_8 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 428.0
PYH2_k127_6835537_9 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 414.0
PYH2_k127_6844450_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.24e-207 669.0
PYH2_k127_6844450_1 Methionine synthase K00549 - 2.1.1.14 3.407e-194 614.0
PYH2_k127_6844450_10 - - - - 0.000000000000000000000000000000000000000000004192 171.0
PYH2_k127_6844450_12 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000001594 130.0
PYH2_k127_6844450_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000006885 113.0
PYH2_k127_6844450_14 Bacterial regulatory proteins, crp family K10914 - - 0.000000000000001227 83.0
PYH2_k127_6844450_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 482.0
PYH2_k127_6844450_3 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 466.0
PYH2_k127_6844450_4 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 422.0
PYH2_k127_6844450_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 331.0
PYH2_k127_6844450_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
PYH2_k127_6844450_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002565 271.0
PYH2_k127_6844450_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
PYH2_k127_6844450_9 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000197 184.0
PYH2_k127_6955752_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.707e-232 736.0
PYH2_k127_6955752_1 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 421.0
PYH2_k127_6955752_2 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000001742 102.0
PYH2_k127_6955752_3 - - - - 0.00000000000000004103 81.0
PYH2_k127_699579_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 550.0
PYH2_k127_699579_1 YqeY-like protein K09117 - - 0.000000000000000000000000000000000000000000000001154 182.0
PYH2_k127_699579_2 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000002564 123.0
PYH2_k127_699579_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000003997 115.0
PYH2_k127_700845_0 Tyrosine recombinase xerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 369.0
PYH2_k127_700845_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 348.0
PYH2_k127_700845_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 292.0
PYH2_k127_700845_3 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
PYH2_k127_700845_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000001178 186.0
PYH2_k127_700845_5 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.00000000000000000000000000000000000002559 145.0
PYH2_k127_700845_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000005073 124.0
PYH2_k127_7013644_0 acyl-CoA dehydrogenase K06445 - - 1.265e-316 1001.0
PYH2_k127_7013644_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.878e-202 636.0
PYH2_k127_7013644_2 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 388.0
PYH2_k127_7013644_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000006152 221.0
PYH2_k127_7052010_0 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 359.0
PYH2_k127_7052010_1 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 367.0
PYH2_k127_7052010_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002754 259.0
PYH2_k127_7052010_3 - - - - 0.0005102 43.0
PYH2_k127_705532_0 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 449.0
PYH2_k127_705532_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000285 200.0
PYH2_k127_7059041_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1063.0
PYH2_k127_7059041_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 471.0
PYH2_k127_7059041_2 (ABC) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 343.0
PYH2_k127_7059041_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004693 244.0
PYH2_k127_7059041_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000003721 225.0
PYH2_k127_7059041_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000002442 145.0
PYH2_k127_706594_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 7.405e-245 762.0
PYH2_k127_706594_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005535 278.0
PYH2_k127_706779_0 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 4.174e-215 678.0
PYH2_k127_706779_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.728e-213 694.0
PYH2_k127_706779_10 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
PYH2_k127_706779_11 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001251 267.0
PYH2_k127_706779_12 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000094 74.0
PYH2_k127_706779_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 508.0
PYH2_k127_706779_3 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 511.0
PYH2_k127_706779_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 485.0
PYH2_k127_706779_5 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 384.0
PYH2_k127_706779_6 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 393.0
PYH2_k127_706779_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 372.0
PYH2_k127_706779_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 350.0
PYH2_k127_706779_9 leucine import across plasma membrane K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
PYH2_k127_7069468_0 Malic enzyme K00029 - 1.1.1.40 0.0 1056.0
PYH2_k127_7069468_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 365.0
PYH2_k127_7161749_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 504.0
PYH2_k127_7161749_1 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
PYH2_k127_7161749_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000005462 233.0
PYH2_k127_7161749_3 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000138 201.0
PYH2_k127_7161749_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000009246 173.0
PYH2_k127_7179892_0 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 475.0
PYH2_k127_7179892_1 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 374.0
PYH2_k127_7179892_2 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 301.0
PYH2_k127_7179892_3 response to antibiotic - - - 0.0000000000000000000000000000000000001093 153.0
PYH2_k127_7184102_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.941e-199 634.0
PYH2_k127_7184102_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 400.0
PYH2_k127_7184102_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 360.0
PYH2_k127_7184102_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 298.0
PYH2_k127_7184102_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000003639 175.0
PYH2_k127_7184102_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000004066 121.0
PYH2_k127_7185866_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 378.0
PYH2_k127_7185866_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 355.0
PYH2_k127_7185866_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000004026 174.0
PYH2_k127_7185866_3 Protein of unknown function (DUF2782) - - - 0.00000000000000000000004527 104.0
PYH2_k127_7186512_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 380.0
PYH2_k127_7186512_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 336.0
PYH2_k127_7186512_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 334.0
PYH2_k127_7186512_3 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000484 117.0
PYH2_k127_7244613_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1283.0
PYH2_k127_7244613_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000005155 118.0
PYH2_k127_7261263_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 514.0
PYH2_k127_7261263_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000001552 183.0
PYH2_k127_7261263_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000001443 104.0
PYH2_k127_7287827_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 560.0
PYH2_k127_7287827_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 391.0
PYH2_k127_7287827_2 Sterol carrier protein - - - 0.0000000000000001738 85.0
PYH2_k127_7287827_3 CoA-transferase family III - - - 0.00006212 48.0
PYH2_k127_7313127_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 4.66e-280 871.0
PYH2_k127_7334238_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 7.411e-219 697.0
PYH2_k127_7350729_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 399.0
PYH2_k127_7350729_1 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005239 279.0
PYH2_k127_7376403_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 331.0
PYH2_k127_7376403_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006967 286.0
PYH2_k127_7376403_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000009625 64.0
PYH2_k127_7402034_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 485.0
PYH2_k127_7402034_1 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003382 256.0
PYH2_k127_7402034_2 AI-2E family transporter - - - 0.000000000000000000000000000007452 132.0
PYH2_k127_7441176_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 340.0
PYH2_k127_7441176_1 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008139 262.0
PYH2_k127_7441176_2 Transcriptional regulator, Crp Fnr family K21563 - - 0.0000000000000732 81.0
PYH2_k127_7441176_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000002652 59.0
PYH2_k127_7483704_0 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 456.0
PYH2_k127_7483704_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 445.0
PYH2_k127_7532316_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1394.0
PYH2_k127_7532316_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000974 146.0
PYH2_k127_7605963_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.775e-257 801.0
PYH2_k127_7605963_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000125 60.0
PYH2_k127_7619135_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 589.0
PYH2_k127_7619135_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 501.0
PYH2_k127_7619135_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 461.0
PYH2_k127_7619135_3 MAPEG family - - - 0.00000000000000002605 86.0
PYH2_k127_7619135_4 AMP-binding enzyme - - - 0.0001919 44.0
PYH2_k127_7624544_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 459.0
PYH2_k127_7624544_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 377.0
PYH2_k127_7633563_0 Prolyl oligopeptidase family - - - 5.8e-245 776.0
PYH2_k127_7633563_1 Zn_pept - - - 1.005e-228 721.0
PYH2_k127_7633563_10 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000185 106.0
PYH2_k127_7633563_2 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 379.0
PYH2_k127_7633563_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 298.0
PYH2_k127_7633563_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001469 263.0
PYH2_k127_7633563_5 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
PYH2_k127_7633563_6 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
PYH2_k127_7633563_7 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000004738 218.0
PYH2_k127_7633563_8 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000007277 173.0
PYH2_k127_7633563_9 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.00000000000000000000000000000004067 134.0
PYH2_k127_7642780_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 4.947e-212 668.0
PYH2_k127_7642780_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000001218 207.0
PYH2_k127_7648401_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.12e-319 998.0
PYH2_k127_7648401_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005744 268.0
PYH2_k127_7651064_0 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 409.0
PYH2_k127_7651064_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
PYH2_k127_7651064_2 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005238 283.0
PYH2_k127_7651064_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000003109 228.0
PYH2_k127_7651064_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000003495 222.0
PYH2_k127_7651064_5 Molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000005363 83.0
PYH2_k127_7659094_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 324.0
PYH2_k127_7659094_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 293.0
PYH2_k127_7659094_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
PYH2_k127_7659094_3 Pfam Response regulator receiver - - - 0.0000000000001682 75.0
PYH2_k127_7665690_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 317.0
PYH2_k127_7665690_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
PYH2_k127_7665690_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000009179 154.0
PYH2_k127_7665690_3 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000007659 97.0
PYH2_k127_7674628_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968,K13777 - 6.4.1.4,6.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 449.0
PYH2_k127_7674628_1 acyl-CoA dehydrogenase K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 303.0
PYH2_k127_7674628_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000001677 155.0
PYH2_k127_7684916_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004876 276.0
PYH2_k127_7684916_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000001584 209.0
PYH2_k127_7684916_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000006107 72.0
PYH2_k127_7688610_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.017e-267 841.0
PYH2_k127_7688610_1 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 609.0
PYH2_k127_7688610_2 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 398.0
PYH2_k127_7688610_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
PYH2_k127_7688610_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 313.0
PYH2_k127_7688610_5 FixH family K09926 - - 0.0000000000000000001182 93.0
PYH2_k127_7688610_6 COG4736 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.0000000611 63.0
PYH2_k127_7703527_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.233e-286 883.0
PYH2_k127_7703527_1 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.535e-245 764.0
PYH2_k127_7703527_10 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000002476 203.0
PYH2_k127_7703527_11 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000002048 188.0
PYH2_k127_7703527_12 glycosyl transferase K12983,K12988,K19354 - - 0.000000000000000000000000000000000000000000008236 177.0
PYH2_k127_7703527_13 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000007677 160.0
PYH2_k127_7703527_14 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000001946 121.0
PYH2_k127_7703527_15 Domain of unknown function (DUF4124) - - - 0.000000000000000000003074 100.0
PYH2_k127_7703527_2 Belongs to the malate synthase family K01638 - 2.3.3.9 5.891e-241 755.0
PYH2_k127_7703527_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 3.774e-206 657.0
PYH2_k127_7703527_4 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 561.0
PYH2_k127_7703527_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 486.0
PYH2_k127_7703527_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 409.0
PYH2_k127_7703527_7 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 381.0
PYH2_k127_7703527_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 362.0
PYH2_k127_7703527_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 348.0
PYH2_k127_7708749_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1217.0
PYH2_k127_7745072_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.947e-195 622.0
PYH2_k127_7745072_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 455.0
PYH2_k127_7745072_2 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000002276 97.0
PYH2_k127_7754213_0 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 415.0
PYH2_k127_7754213_1 - - - - 0.0000000000000000000000000000000000000000000000000001769 201.0
PYH2_k127_7754213_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000001395 167.0
PYH2_k127_7757456_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 427.0
PYH2_k127_7757456_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
PYH2_k127_7769206_0 twitching motility protein K02670 - - 1.22e-202 638.0
PYH2_k127_7769206_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 619.0
PYH2_k127_7769206_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 278.0
PYH2_k127_7769206_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000001114 104.0
PYH2_k127_7769206_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000002053 93.0
PYH2_k127_7783450_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.38e-259 807.0
PYH2_k127_7783450_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000001871 109.0
PYH2_k127_7794373_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.451e-308 954.0
PYH2_k127_7794373_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 570.0
PYH2_k127_7794373_10 RDD family - - - 0.000000000000000000000007608 112.0
PYH2_k127_7794373_11 Protein of unknown function (DUF3619) - - - 0.0000000000000004023 85.0
PYH2_k127_7794373_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
PYH2_k127_7794373_3 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 369.0
PYH2_k127_7794373_4 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 383.0
PYH2_k127_7794373_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 308.0
PYH2_k127_7794373_6 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
PYH2_k127_7794373_7 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
PYH2_k127_7794373_8 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000009929 251.0
PYH2_k127_7794373_9 Protein of unknown function (DUF3106) - - - 0.000000000000000000000001593 114.0
PYH2_k127_780054_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 548.0
PYH2_k127_7808162_0 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 411.0
PYH2_k127_7808162_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000171 279.0
PYH2_k127_7811544_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 1.075e-241 759.0
PYH2_k127_7811544_1 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 492.0
PYH2_k127_7811544_10 - - - - 0.000000000000003999 82.0
PYH2_k127_7811544_11 Prokaryotic N-terminal methylation motif - - - 0.00000000000001956 74.0
PYH2_k127_7811544_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 451.0
PYH2_k127_7811544_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002835 257.0
PYH2_k127_7811544_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004552 236.0
PYH2_k127_7811544_6 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000002958 191.0
PYH2_k127_7811544_7 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000002762 173.0
PYH2_k127_7811544_8 general secretion pathway protein - - - 0.000000000000000000000000000000001723 148.0
PYH2_k127_7811544_9 - - - - 0.0000000000000000000000005374 114.0
PYH2_k127_7815693_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 497.0
PYH2_k127_7815693_1 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000001099 199.0
PYH2_k127_7815693_2 - - - - 0.000000000000000000000000000000000000000006668 169.0
PYH2_k127_7829960_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 442.0
PYH2_k127_7829960_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 310.0
PYH2_k127_7840464_0 Acyl-CoA dehydrogenase N terminal K20035 - - 3.109e-246 788.0
PYH2_k127_7840464_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 591.0
PYH2_k127_7840464_2 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 453.0
PYH2_k127_7840464_3 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 355.0
PYH2_k127_7846752_0 Protein of unknown function (DUF3141) - - - 0.0 1034.0
PYH2_k127_7846752_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.751e-315 978.0
PYH2_k127_7846752_10 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 295.0
PYH2_k127_7846752_11 sulfur relay protein TusD DsrE K07235 - - 0.0000000000000000000000000000000000000000000000000000000000006119 211.0
PYH2_k127_7846752_12 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000005565 199.0
PYH2_k127_7846752_13 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000000000000000000000000008196 190.0
PYH2_k127_7846752_14 - - - - 0.000000000000000000000000000000000000000000000000009887 193.0
PYH2_k127_7846752_15 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000001975 177.0
PYH2_k127_7846752_16 DsrC like protein K11179 - - 0.000000000000000000000000000000000000007896 159.0
PYH2_k127_7846752_17 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000004127 144.0
PYH2_k127_7846752_18 DsrH like protein K07237 - - 0.000000000000000000000000000000001948 138.0
PYH2_k127_7846752_19 Cas6 Crispr - - - 0.000000000000000000000000000004623 130.0
PYH2_k127_7846752_2 Fe-S oxidoreductase K21834 - - 4.262e-251 784.0
PYH2_k127_7846752_20 - - - - 0.000000000000000000000000006934 110.0
PYH2_k127_7846752_21 - - - - 0.00000000000000000000000001039 116.0
PYH2_k127_7846752_22 - - - - 0.00000000000000000000000003465 123.0
PYH2_k127_7846752_23 - - - - 0.0000000000000000008601 92.0
PYH2_k127_7846752_24 belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 0.0000000001344 63.0
PYH2_k127_7846752_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.775e-218 688.0
PYH2_k127_7846752_4 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 5.565e-204 672.0
PYH2_k127_7846752_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 506.0
PYH2_k127_7846752_6 PFAM phosphate acetyl butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 458.0
PYH2_k127_7846752_7 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 355.0
PYH2_k127_7846752_8 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 350.0
PYH2_k127_7846752_9 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 317.0
PYH2_k127_7860833_0 cytochrome c biogenesis K02198 - - 4.173e-264 826.0
PYH2_k127_7860833_1 Redoxin K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000009484 248.0
PYH2_k127_7860833_2 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000003919 140.0
PYH2_k127_7868883_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 593.0
PYH2_k127_7868883_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000005359 203.0
PYH2_k127_7868883_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000002153 93.0
PYH2_k127_7872158_0 CRP FNR family K21563 - - 0.00000000000000000000000000000000000000105 156.0
PYH2_k127_7872158_1 Universal stress protein - - - 0.00000000000000000000000000000000005898 139.0
PYH2_k127_7872158_2 Universal stress protein - - - 0.00000000000000000000000000000000023 139.0
PYH2_k127_7872158_3 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000003562 80.0
PYH2_k127_7881458_0 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 413.0
PYH2_k127_7881458_1 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
PYH2_k127_7881458_2 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002483 273.0
PYH2_k127_7881458_3 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000001975 217.0
PYH2_k127_7881458_4 VanZ like family - - - 0.0000000000000000000000000000000000000000000000009121 182.0
PYH2_k127_7881458_5 Ferredoxin - - - 0.0000000000000000000000000000000000000000000003933 168.0
PYH2_k127_7888249_0 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 514.0
PYH2_k127_7888249_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 419.0
PYH2_k127_7888249_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
PYH2_k127_7888249_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 275.0
PYH2_k127_7888249_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000001069 165.0
PYH2_k127_7888249_5 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000004017 153.0
PYH2_k127_7888249_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000001079 63.0
PYH2_k127_7891332_0 FAD FMN-containing dehydrogenases - - - 7.779e-202 634.0
PYH2_k127_7891332_1 FAD binding domain K11472 - - 0.00000000000000000000000000000009867 136.0
PYH2_k127_7896919_0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000001441 185.0
PYH2_k127_7896919_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000009693 163.0
PYH2_k127_7896919_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000001976 150.0
PYH2_k127_7896919_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000001674 119.0
PYH2_k127_7903452_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 350.0
PYH2_k127_7903452_1 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002136 260.0
PYH2_k127_7903452_2 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000002753 150.0
PYH2_k127_7908173_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
PYH2_k127_7908173_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 505.0
PYH2_k127_7908173_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 300.0
PYH2_k127_7908173_3 Glycosyltransferase like family 2 K13002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 279.0
PYH2_k127_7908173_4 ABC transporter K01990,K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000112 276.0
PYH2_k127_7908173_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006524 241.0
PYH2_k127_7908173_7 ADP-glyceromanno-heptose 6-epimerase activity K19997,K22320 - 1.1.1.412,5.1.3.26 0.0000000000000000000000000000000000000000000000000000001576 207.0
PYH2_k127_7908173_8 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.0000000000000000000000000000000000000000000000000000004559 201.0
PYH2_k127_7908173_9 PFAM ABC-2 type transporter K01992,K09690 - - 0.000000000000000000000000000000001345 134.0
PYH2_k127_7966421_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 3.685e-263 841.0
PYH2_k127_7966421_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 330.0
PYH2_k127_7966421_2 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
PYH2_k127_7966421_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000002361 194.0
PYH2_k127_7980695_0 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 423.0
PYH2_k127_7980695_1 Two-component sensor kinase N-terminal - - - 0.0000000000000000000000000000000000000000007642 161.0
PYH2_k127_7980695_2 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.0000000000001566 77.0
PYH2_k127_7993884_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 5.517e-215 684.0
PYH2_k127_7993884_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000133 113.0
PYH2_k127_8020077_0 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 399.0
PYH2_k127_8020077_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 317.0
PYH2_k127_8020077_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 259.0
PYH2_k127_8020077_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000007799 134.0
PYH2_k127_8020077_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.0002152 45.0
PYH2_k127_8039805_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 404.0
PYH2_k127_8039805_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 360.0
PYH2_k127_8039805_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000008536 234.0
PYH2_k127_8039805_3 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000000000001076 201.0
PYH2_k127_8039805_4 Belongs to the BolA IbaG family - - - 0.0000000000000000003539 99.0
PYH2_k127_8039805_5 STAS domain K07122 - - 0.00000000000001631 77.0
PYH2_k127_8062001_0 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 299.0
PYH2_k127_8062001_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000008009 180.0
PYH2_k127_8062001_2 AraC-like ligand binding domain - - - 0.000000000000000000000000000000002562 141.0
PYH2_k127_8062403_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 559.0
PYH2_k127_8062403_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 558.0
PYH2_k127_8062403_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 500.0
PYH2_k127_8062403_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 452.0
PYH2_k127_8062403_4 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 388.0
PYH2_k127_8062403_5 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 371.0
PYH2_k127_8062403_6 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 351.0
PYH2_k127_8062403_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 316.0
PYH2_k127_8066432_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 7.992e-223 709.0
PYH2_k127_8066432_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
PYH2_k127_8066432_2 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 367.0
PYH2_k127_8066432_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000001885 198.0
PYH2_k127_8066432_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000003514 137.0
PYH2_k127_8066432_5 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000004923 121.0
PYH2_k127_8066432_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000002873 83.0
PYH2_k127_8075734_0 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
PYH2_k127_8075734_1 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000002757 272.0
PYH2_k127_8075734_2 belongs to the aldehyde dehydrogenase family K22187 - - 0.0000001153 63.0
PYH2_k127_8078265_0 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000003516 186.0
PYH2_k127_8078265_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000002792 142.0
PYH2_k127_8078265_2 RNB-like protein K01147 - 3.1.13.1 0.0000000000000000000001867 100.0
PYH2_k127_8084966_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 370.0
PYH2_k127_8084966_1 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 359.0
PYH2_k127_8084966_2 phytoene K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
PYH2_k127_8118578_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 398.0
PYH2_k127_8118578_1 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 325.0
PYH2_k127_8118578_2 COGs COG4446 conserved - - - 0.0000000000000000000000000000003922 127.0
PYH2_k127_8126058_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.616e-226 722.0
PYH2_k127_8126058_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
PYH2_k127_8126058_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000003983 133.0
PYH2_k127_8145497_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 432.0
PYH2_k127_8145497_1 SBF-like CPA transporter family (DUF4137) K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 389.0
PYH2_k127_8153545_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 4.272e-226 725.0
PYH2_k127_8153545_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 293.0
PYH2_k127_8175806_0 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 585.0
PYH2_k127_8175806_1 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 454.0
PYH2_k127_8175806_2 Universal stress protein family - - - 0.000000000000000000000000000000000000169 152.0
PYH2_k127_8175806_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000005032 98.0
PYH2_k127_8194926_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.891e-253 787.0
PYH2_k127_8194926_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 441.0
PYH2_k127_8194926_2 Thioredoxin-like - - - 0.000000000000000000000000000155 129.0
PYH2_k127_8209022_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000003538 248.0
PYH2_k127_8209022_1 FtsX-like permease family K02004 - - 0.00000005197 55.0
PYH2_k127_8209022_2 Amidohydrolase family - - - 0.00000006864 53.0
PYH2_k127_8211847_0 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 346.0
PYH2_k127_8211847_1 - - - - 0.0000000002243 71.0
PYH2_k127_8211847_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000002462 61.0
PYH2_k127_8212193_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 551.0
PYH2_k127_8212193_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000001428 95.0
PYH2_k127_821281_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.622e-226 708.0
PYH2_k127_821281_1 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 544.0
PYH2_k127_821281_2 TatD related DNase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 505.0
PYH2_k127_821281_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 493.0
PYH2_k127_821281_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 316.0
PYH2_k127_821281_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003867 277.0
PYH2_k127_821281_6 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000004726 192.0
PYH2_k127_821281_7 Xylose isomerase domain protein TIM barrel - - - 0.000009192 58.0
PYH2_k127_821281_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0002475 49.0
PYH2_k127_8243704_0 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 531.0
PYH2_k127_8243704_1 Glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 341.0
PYH2_k127_8243704_2 ADP-glyceromanno-heptose 6-epimerase activity K19997,K22320 - 1.1.1.412,5.1.3.26 0.000003079 51.0
PYH2_k127_8268232_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.505e-205 653.0
PYH2_k127_8268232_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 550.0
PYH2_k127_8268232_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 415.0
PYH2_k127_8268232_3 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 322.0
PYH2_k127_8268232_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000001891 169.0
PYH2_k127_8290558_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.637e-287 893.0
PYH2_k127_8290558_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 287.0
PYH2_k127_8290558_2 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000001823 184.0
PYH2_k127_8290558_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000001434 164.0
PYH2_k127_8290558_4 Ribonuclease K01167 - 3.1.27.3 0.00000000000000000000000000000004243 128.0
PYH2_k127_8290558_5 Putative regulatory protein - - - 0.00000000000000000000000000000385 121.0
PYH2_k127_8290558_6 Barstar (barnase inhibitor) - - - 0.000000000000000002757 89.0
PYH2_k127_8293673_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 446.0
PYH2_k127_8293673_1 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 411.0
PYH2_k127_8293673_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000002618 202.0
PYH2_k127_8293673_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000006896 98.0
PYH2_k127_8302590_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1097.0
PYH2_k127_8302590_1 DNA polymerase X family K02347 - - 2.471e-228 720.0
PYH2_k127_8302590_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 524.0
PYH2_k127_8302590_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 505.0
PYH2_k127_8302590_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
PYH2_k127_8302590_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000005145 232.0
PYH2_k127_8302590_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000006125 183.0
PYH2_k127_8302590_7 cytochrome c K17223 - - 0.000000000000000000000000000000000000000002743 170.0
PYH2_k127_8302590_8 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000006449 154.0
PYH2_k127_8302590_9 - - - - 0.0000000000000000001323 93.0
PYH2_k127_8303061_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 400.0
PYH2_k127_8303061_1 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 364.0
PYH2_k127_8303061_2 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000001328 140.0
PYH2_k127_8303061_3 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000963 108.0
PYH2_k127_8310113_0 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 319.0
PYH2_k127_8310113_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000001123 247.0
PYH2_k127_8310113_2 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000001719 229.0
PYH2_k127_8310113_3 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000001247 156.0
PYH2_k127_8310113_4 - - - - 0.00000000000000000000000002344 115.0
PYH2_k127_8324067_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.57e-233 728.0
PYH2_k127_8324067_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 532.0
PYH2_k127_8324067_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
PYH2_k127_8324067_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000003567 216.0
PYH2_k127_8324067_12 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000001574 201.0
PYH2_k127_8324067_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000001083 188.0
PYH2_k127_8324067_14 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000003992 188.0
PYH2_k127_8324067_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000009286 181.0
PYH2_k127_8324067_16 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000001179 172.0
PYH2_k127_8324067_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000002966 154.0
PYH2_k127_8324067_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000006653 137.0
PYH2_k127_8324067_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000001487 134.0
PYH2_k127_8324067_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 341.0
PYH2_k127_8324067_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000008884 120.0
PYH2_k127_8324067_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000008734 89.0
PYH2_k127_8324067_22 Ribosomal protein L30 K02907 - - 0.00000000000000001867 84.0
PYH2_k127_8324067_23 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000006153 68.0
PYH2_k127_8324067_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 329.0
PYH2_k127_8324067_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
PYH2_k127_8324067_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 280.0
PYH2_k127_8324067_6 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001655 276.0
PYH2_k127_8324067_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001452 265.0
PYH2_k127_8324067_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000263 239.0
PYH2_k127_8324067_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000001287 220.0
PYH2_k127_8331508_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 341.0
PYH2_k127_8331508_1 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 321.0
PYH2_k127_8339157_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 7.306e-276 859.0
PYH2_k127_8339157_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000006991 87.0
PYH2_k127_8348886_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
PYH2_k127_8348886_1 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000007205 181.0
PYH2_k127_8348886_2 membrane transporter protein K07090 - - 0.0001568 48.0
PYH2_k127_8353433_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 2.946e-314 1007.0
PYH2_k127_8353433_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 1.798e-238 747.0
PYH2_k127_8353433_2 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 458.0
PYH2_k127_8368629_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1067.0
PYH2_k127_8368629_1 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 537.0
PYH2_k127_8368629_10 - - - - 0.00001893 50.0
PYH2_k127_8368629_2 Aminotransferase K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 527.0
PYH2_k127_8368629_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 514.0
PYH2_k127_8368629_4 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 447.0
PYH2_k127_8368629_5 Formate/nitrite transporter K06212,K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 405.0
PYH2_k127_8368629_6 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 377.0
PYH2_k127_8368629_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000000001272 204.0
PYH2_k127_8368629_8 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000001213 184.0
PYH2_k127_8368629_9 Universal stress protein - - - 0.00000000000000000000000002762 114.0
PYH2_k127_8373042_0 VWA domain containing CoxE-like protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 579.0
PYH2_k127_8373042_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 494.0
PYH2_k127_8373042_2 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 426.0
PYH2_k127_8373042_3 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000008766 63.0
PYH2_k127_8381264_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 323.0
PYH2_k127_8381264_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009914 270.0
PYH2_k127_8381264_2 Aldo keto - - - 0.0000000000000000000000000000000000000000000000000000000000000002257 227.0
PYH2_k127_8399089_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 365.0
PYH2_k127_8399089_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 336.0
PYH2_k127_8399089_2 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000006963 156.0
PYH2_k127_8399089_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000002206 134.0
PYH2_k127_8399876_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.113e-246 768.0
PYH2_k127_8399876_1 Adenylate cyclase K01768 - 4.6.1.1 5.124e-215 682.0
PYH2_k127_8399876_2 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000001259 217.0
PYH2_k127_8399876_3 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000001816 138.0
PYH2_k127_8399876_4 PFAM NnrS family protein K07234 - - 0.0000000000006958 70.0
PYH2_k127_8399876_5 - K01611 - 4.1.1.50 0.00000005474 59.0
PYH2_k127_8402133_0 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 608.0
PYH2_k127_8402133_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 310.0
PYH2_k127_8402133_2 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000007143 162.0
PYH2_k127_8403150_0 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 436.0
PYH2_k127_8403150_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
PYH2_k127_8403150_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000003448 173.0
PYH2_k127_8403150_3 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000000000000001273 140.0
PYH2_k127_8403150_4 Mg chelatase subunit ChlI K07391 - - 0.00000000000000000000004415 100.0
PYH2_k127_8429458_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.003e-283 907.0
PYH2_k127_8429458_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.61e-197 621.0
PYH2_k127_8429458_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 569.0
PYH2_k127_8429458_3 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000001272 149.0
PYH2_k127_8429458_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000001108 141.0
PYH2_k127_8429458_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000001315 119.0
PYH2_k127_8429458_6 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000004407 78.0
PYH2_k127_8448226_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007276 284.0
PYH2_k127_8451343_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 390.0
PYH2_k127_8451343_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
PYH2_k127_8451343_2 Alanine acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001083 196.0
PYH2_k127_8451343_3 Ankyrin repeat - - - 0.0000000000003719 82.0
PYH2_k127_8463880_0 extracellular solute-binding protein - - - 2.528e-293 930.0
PYH2_k127_8463880_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 537.0
PYH2_k127_8463880_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 513.0
PYH2_k127_8463880_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 381.0
PYH2_k127_8463880_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000003196 164.0
PYH2_k127_8463880_5 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000003626 54.0
PYH2_k127_8488218_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 317.0
PYH2_k127_8488218_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000003728 152.0
PYH2_k127_8488218_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000003236 85.0
PYH2_k127_8501016_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 341.0
PYH2_k127_8501016_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 318.0
PYH2_k127_8501016_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001924 246.0
PYH2_k127_8501016_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
PYH2_k127_8501016_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000000000000002152 160.0
PYH2_k127_8501016_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007891 79.0
PYH2_k127_8501016_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000002817 55.0
PYH2_k127_8502317_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1042.0
PYH2_k127_8502317_1 impB/mucB/samB family K14161 - - 0.0000000000000000000000000000000002438 136.0
PYH2_k127_8504860_0 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 385.0
PYH2_k127_8504860_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 341.0
PYH2_k127_8504860_2 Domain of unknown function (DUF4124) - - - 0.00000000000000000003389 98.0
PYH2_k127_8505666_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 5.18e-257 812.0
PYH2_k127_8505666_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.072e-226 708.0
PYH2_k127_8505666_10 Protein of unknown function (DUF3460) - - - 0.000004239 59.0
PYH2_k127_8505666_2 Belongs to the citrate synthase family K01659 - 2.3.3.5 4.201e-199 640.0
PYH2_k127_8505666_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 480.0
PYH2_k127_8505666_4 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 435.0
PYH2_k127_8505666_5 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 426.0
PYH2_k127_8505666_6 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000003217 147.0
PYH2_k127_8505666_7 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000005379 148.0
PYH2_k127_8505666_8 Dehydrogenase E1 component K00164 - 1.2.4.2 0.000000000000000000003564 108.0
PYH2_k127_8505666_9 Flavinator of succinate dehydrogenase K09159 - - 0.00000008603 61.0
PYH2_k127_8505798_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
PYH2_k127_8505798_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
PYH2_k127_8505798_2 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 361.0
PYH2_k127_8505798_3 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 316.0
PYH2_k127_8505798_4 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
PYH2_k127_8505798_5 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003061 291.0
PYH2_k127_8505798_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 273.0
PYH2_k127_8505798_7 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000004149 204.0
PYH2_k127_8505798_8 Aminotransferase K09758 - 4.1.1.12 0.000000000000000000000000000000002584 132.0
PYH2_k127_8505798_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000008237 67.0
PYH2_k127_8506411_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 428.0
PYH2_k127_8506411_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 441.0
PYH2_k127_8506411_2 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000006556 108.0
PYH2_k127_8506411_3 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000007517 107.0
PYH2_k127_8506411_4 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000122 100.0
PYH2_k127_8506411_5 Maf-like protein K06287 - - 0.000000000002391 71.0
PYH2_k127_8518683_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 3.715e-236 739.0
PYH2_k127_8518683_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 7.831e-232 724.0
PYH2_k127_8518683_10 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000002325 193.0
PYH2_k127_8518683_11 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000002845 181.0
PYH2_k127_8518683_12 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000005427 172.0
PYH2_k127_8518683_13 acetyltransferase - - - 0.0000000000000000000000000000007129 131.0
PYH2_k127_8518683_14 Small Multidrug Resistance protein - - - 0.000000000000000000000000004219 115.0
PYH2_k127_8518683_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000002632 71.0
PYH2_k127_8518683_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.672e-208 662.0
PYH2_k127_8518683_3 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 536.0
PYH2_k127_8518683_4 Glycosyl transferase family 2 K13670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 372.0
PYH2_k127_8518683_5 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 342.0
PYH2_k127_8518683_6 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 306.0
PYH2_k127_8518683_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008702 241.0
PYH2_k127_8518683_8 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000006705 228.0
PYH2_k127_8518683_9 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000001024 203.0
PYH2_k127_8519669_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 296.0
PYH2_k127_8519669_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008698 269.0
PYH2_k127_8519669_2 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000001608 96.0
PYH2_k127_8519669_3 - - - - 0.00000000000000000001275 92.0
PYH2_k127_8520688_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1281.0
PYH2_k127_8520688_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 504.0
PYH2_k127_8520688_10 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000008588 53.0
PYH2_k127_8520688_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 385.0
PYH2_k127_8520688_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 383.0
PYH2_k127_8520688_4 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 368.0
PYH2_k127_8520688_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 327.0
PYH2_k127_8520688_6 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 316.0
PYH2_k127_8520688_7 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000009403 170.0
PYH2_k127_8520688_8 Thioesterase - - - 0.000000000000000000000000000000000000000000002749 167.0
PYH2_k127_8520688_9 transcriptional regulator - - - 0.000000000000000000000003856 119.0
PYH2_k127_8522938_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 437.0
PYH2_k127_8522938_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000101 218.0
PYH2_k127_8522938_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0000000000000000000000000000000000000000000005597 170.0
PYH2_k127_8522938_3 dksA traR - - - 0.00000000000000000000000002374 113.0
PYH2_k127_8522938_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000007889 50.0
PYH2_k127_8526241_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 541.0
PYH2_k127_8526241_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 470.0
PYH2_k127_8526241_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 430.0
PYH2_k127_8526241_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
PYH2_k127_8526241_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000001345 185.0
PYH2_k127_8526705_0 4Fe-4S dicluster domain - - - 0.0 1219.0
PYH2_k127_8526705_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 592.0
PYH2_k127_8526705_10 SMART Transport-associated and nodulation region K04065 - - 0.0000000001539 73.0
PYH2_k127_8526705_2 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 590.0
PYH2_k127_8526705_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 550.0
PYH2_k127_8526705_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
PYH2_k127_8526705_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 364.0
PYH2_k127_8526705_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 340.0
PYH2_k127_8526705_7 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 317.0
PYH2_k127_8526705_8 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 310.0
PYH2_k127_8526705_9 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000004535 238.0
PYH2_k127_8529509_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 512.0
PYH2_k127_8529509_1 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 396.0
PYH2_k127_8529509_2 Major Facilitator Superfamily - - - 0.0000000000000000007642 90.0
PYH2_k127_8538352_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 514.0
PYH2_k127_8538352_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
PYH2_k127_8538352_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000005677 211.0
PYH2_k127_8538352_3 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000002764 200.0
PYH2_k127_8538352_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000006212 120.0
PYH2_k127_8538352_5 Amidohydrolase family K01461 - 3.5.1.82 0.00000000002396 75.0
PYH2_k127_8551710_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000587 246.0
PYH2_k127_8551710_1 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000003244 136.0
PYH2_k127_8551710_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000001761 121.0
PYH2_k127_8559481_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 444.0
PYH2_k127_8559481_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 396.0
PYH2_k127_8559481_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 329.0
PYH2_k127_8559481_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000001481 94.0
PYH2_k127_8561732_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1451.0
PYH2_k127_8561732_1 Carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 399.0
PYH2_k127_8564038_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000004468 98.0
PYH2_k127_8564038_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00001686 57.0
PYH2_k127_8568760_0 STAS domain K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 575.0
PYH2_k127_8568760_1 to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000001793 128.0
PYH2_k127_8569652_0 FAD linked oxidase domain protein K06911 - - 2.282e-223 703.0
PYH2_k127_8584264_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 489.0
PYH2_k127_8584264_1 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 414.0
PYH2_k127_8584264_2 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
PYH2_k127_8584264_3 2-keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000003575 212.0
PYH2_k127_8584264_4 Luciferase-like monooxygenase - - - 0.000000001802 68.0
PYH2_k127_8584264_5 PFAM major facilitator superfamily MFS_1 - - - 0.0000001224 64.0
PYH2_k127_8584264_6 DNA-sulfur modification-associated - - - 0.000001013 61.0
PYH2_k127_8588770_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 375.0
PYH2_k127_8606460_0 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 485.0
PYH2_k127_8606460_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 274.0
PYH2_k127_8606460_2 DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001526 182.0
PYH2_k127_8606460_3 Belongs to the DnaA family K10763 - - 0.000003419 58.0
PYH2_k127_8617640_0 Dehydratase family K13875 - 4.2.1.25 1.65e-304 942.0
PYH2_k127_8617640_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.814e-283 874.0
PYH2_k127_8617640_10 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 324.0
PYH2_k127_8617640_11 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 334.0
PYH2_k127_8617640_12 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
PYH2_k127_8617640_13 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000005412 156.0
PYH2_k127_8617640_14 subfamily IA, variant 3 - - - 0.00000000000000000000000000008366 118.0
PYH2_k127_8617640_15 protein ubiquitination - - - 0.00002201 54.0
PYH2_k127_8617640_2 Bacterial extracellular solute-binding protein K02027 - - 5.248e-214 672.0
PYH2_k127_8617640_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 2.44e-198 631.0
PYH2_k127_8617640_4 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 518.0
PYH2_k127_8617640_5 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 525.0
PYH2_k127_8617640_6 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 497.0
PYH2_k127_8617640_7 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 487.0
PYH2_k127_8617640_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 436.0
PYH2_k127_8617640_9 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 417.0
PYH2_k127_8629416_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.986e-227 709.0
PYH2_k127_8629416_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 459.0
PYH2_k127_8629416_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 435.0
PYH2_k127_8629416_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 365.0
PYH2_k127_8629416_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 343.0
PYH2_k127_8629416_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000008457 254.0
PYH2_k127_8629416_6 pilus assembly protein FimV K08086 - - 0.00000000000000000000001737 108.0
PYH2_k127_8659370_0 FAD dependent oxidoreductase - - - 5.22e-227 709.0
PYH2_k127_8659370_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 329.0
PYH2_k127_8659370_2 PFAM MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000001413 158.0
PYH2_k127_8674248_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.991e-200 631.0
PYH2_k127_8674248_1 - - - - 0.0000000000000000008779 90.0
PYH2_k127_8704318_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 586.0
PYH2_k127_8704318_1 PFAM VanZ family protein - - - 0.000000000000000000000009952 102.0
PYH2_k127_8705068_0 CoA-binding domain - - - 4.124e-216 704.0
PYH2_k127_8705068_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 625.0
PYH2_k127_8705068_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 359.0
PYH2_k127_8705068_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007397 284.0
PYH2_k127_8705068_4 PFAM Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006473 268.0
PYH2_k127_8705068_5 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000142 212.0
PYH2_k127_8705068_6 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000001805 204.0
PYH2_k127_8705068_7 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000001056 108.0
PYH2_k127_8705068_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000002931 90.0
PYH2_k127_8719563_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 501.0
PYH2_k127_8719563_1 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 435.0
PYH2_k127_8719563_2 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
PYH2_k127_8719563_3 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000006024 123.0
PYH2_k127_8719563_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000005737 121.0
PYH2_k127_8719563_5 PFAM CHAD domain containing protein K01768 - 4.6.1.1 0.0000000000008255 72.0
PYH2_k127_8727805_0 AMP-binding enzyme C-terminal domain K00666 - - 2.459e-271 842.0
PYH2_k127_8727805_1 PERMEase K06901 - - 7.485e-222 709.0
PYH2_k127_8727805_10 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 373.0
PYH2_k127_8727805_11 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 336.0
PYH2_k127_8727805_12 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 328.0
PYH2_k127_8727805_13 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 327.0
PYH2_k127_8727805_14 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 286.0
PYH2_k127_8727805_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 7.434e-205 651.0
PYH2_k127_8727805_3 Extracellular ligand-binding receptor K01999 - - 3.815e-194 613.0
PYH2_k127_8727805_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 568.0
PYH2_k127_8727805_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 495.0
PYH2_k127_8727805_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 444.0
PYH2_k127_8727805_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
PYH2_k127_8727805_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 383.0
PYH2_k127_8727805_9 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 398.0
PYH2_k127_8732037_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 336.0
PYH2_k127_8732037_1 ApaG domain - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
PYH2_k127_8732037_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000224 188.0
PYH2_k127_8738038_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 441.0
PYH2_k127_8738038_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003344 200.0
PYH2_k127_8738038_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000003511 205.0
PYH2_k127_8738038_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000001322 153.0
PYH2_k127_8742372_0 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 467.0
PYH2_k127_8742372_1 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000002627 219.0
PYH2_k127_8742372_2 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000003135 148.0
PYH2_k127_8742372_3 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000008808 135.0
PYH2_k127_8770635_0 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005201 245.0
PYH2_k127_8770635_1 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000001848 139.0
PYH2_k127_8770635_2 Protein of unknown function (DUF541) - - - 0.00000000000000000000000001413 118.0
PYH2_k127_8770635_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000001652 56.0
PYH2_k127_8778038_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 5.24e-256 796.0
PYH2_k127_8778038_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 7.318e-222 702.0
PYH2_k127_8778038_10 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000002494 175.0
PYH2_k127_8778038_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 563.0
PYH2_k127_8778038_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 470.0
PYH2_k127_8778038_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
PYH2_k127_8778038_5 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 366.0
PYH2_k127_8778038_6 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 373.0
PYH2_k127_8778038_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 354.0
PYH2_k127_8778038_8 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 328.0
PYH2_k127_8778038_9 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 317.0
PYH2_k127_8780508_0 RmlD substrate binding domain K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 423.0
PYH2_k127_8780508_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 333.0
PYH2_k127_8780508_2 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000348 241.0
PYH2_k127_8780508_3 Hemolysin-type calcium-binding - - - 0.00000000000000000000000000000000000000000000000000000000000007915 245.0
PYH2_k127_8782477_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 475.0
PYH2_k127_8782477_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 324.0
PYH2_k127_8782477_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 333.0
PYH2_k127_8782477_3 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
PYH2_k127_8782477_4 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000000000001681 220.0
PYH2_k127_8782477_5 sigma 54 modulation protein K05808 - - 0.00000000000000000000000000001094 134.0
PYH2_k127_8784640_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.576e-214 683.0
PYH2_k127_8784640_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 511.0
PYH2_k127_8784640_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 374.0
PYH2_k127_8784640_3 Phosphotransferase System K11189 - - 0.000000000000000000000000000000004933 129.0
PYH2_k127_8784640_4 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000001508 93.0
PYH2_k127_8798161_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
PYH2_k127_8798161_1 Solute carrier family 35 - - - 0.00000000000000000000000000000000000000000000001565 182.0
PYH2_k127_8798161_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000002905 172.0
PYH2_k127_8798161_3 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000002265 155.0
PYH2_k127_8809790_0 luciferase - - - 0.000000000000000000000000000000000000000000000000000000000001249 216.0
PYH2_k127_8809790_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000712 185.0
PYH2_k127_8809790_2 FAD linked oxidase domain protein K06911 - - 0.00000000000000000000000001377 111.0
PYH2_k127_8809790_3 Ankyrin repeat and kinase domain containing 1 K16289 - 2.7.11.1 0.000000000000000000000936 110.0
PYH2_k127_8816453_0 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 492.0
PYH2_k127_8816453_1 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000133 179.0
PYH2_k127_8827214_0 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 542.0
PYH2_k127_8827214_1 amp-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002327 284.0
PYH2_k127_8827214_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000001519 220.0
PYH2_k127_8827214_3 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000001111 180.0
PYH2_k127_8827214_4 membrane - - - 0.000000000000000000000000000000000000000001893 162.0
PYH2_k127_8827214_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000133 113.0
PYH2_k127_8827214_6 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000008018 111.0
PYH2_k127_8827214_7 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000003665 60.0
PYH2_k127_8847053_0 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 490.0
PYH2_k127_8847053_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008852 272.0
PYH2_k127_8847053_2 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000001383 91.0
PYH2_k127_8850643_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1087.0
PYH2_k127_8850643_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 303.0
PYH2_k127_8850643_2 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000188 121.0
PYH2_k127_8858913_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 392.0
PYH2_k127_8858913_1 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 297.0
PYH2_k127_8858913_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000003662 60.0
PYH2_k127_886776_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1215.0
PYH2_k127_886776_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1110.0
PYH2_k127_886776_10 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000001035 181.0
PYH2_k127_886776_11 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000001804 131.0
PYH2_k127_886776_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000001157 63.0
PYH2_k127_886776_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 573.0
PYH2_k127_886776_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
PYH2_k127_886776_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 436.0
PYH2_k127_886776_5 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 385.0
PYH2_k127_886776_6 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 355.0
PYH2_k127_886776_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
PYH2_k127_886776_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000036 271.0
PYH2_k127_886776_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
PYH2_k127_8872835_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 514.0
PYH2_k127_8872835_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000002088 183.0
PYH2_k127_8879599_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 434.0
PYH2_k127_8879599_1 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 403.0
PYH2_k127_8879599_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
PYH2_k127_8879599_3 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000004353 197.0
PYH2_k127_8879599_4 Domain of Unknown Function (DUF748) - - - 0.00003375 50.0
PYH2_k127_8883199_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 584.0
PYH2_k127_8883199_1 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 468.0
PYH2_k127_8883199_2 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 337.0
PYH2_k127_8883199_3 transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000000002064 199.0
PYH2_k127_8883672_0 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000001506 162.0
PYH2_k127_8883672_1 - - - - 0.0000000000000000000006309 110.0
PYH2_k127_8907206_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 524.0
PYH2_k127_8907206_1 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 334.0
PYH2_k127_8907206_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000001123 78.0
PYH2_k127_8916829_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
PYH2_k127_8916829_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 342.0
PYH2_k127_8916829_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000005343 105.0
PYH2_k127_8934175_0 AMP-binding enzyme K01895 - 6.2.1.1 1.965e-237 752.0
PYH2_k127_8934175_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.252e-218 688.0
PYH2_k127_8934175_2 Ammonium Transporter Family K03320,K06580 - - 1.136e-208 654.0
PYH2_k127_8934175_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
PYH2_k127_8934175_4 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
PYH2_k127_8934175_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000003601 209.0
PYH2_k127_8934175_7 Mycolic acid cyclopropane synthetase - - - 0.000000000004643 70.0
PYH2_k127_8950957_0 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 300.0
PYH2_k127_8950957_1 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 293.0
PYH2_k127_8950957_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K15919,K18606 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009853,GO:0009854,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0043094,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.237 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004302 301.0
PYH2_k127_8950957_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000005663 190.0
PYH2_k127_8950957_4 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000000000004244 149.0
PYH2_k127_8961293_0 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 488.0
PYH2_k127_8961293_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
PYH2_k127_8961293_2 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002642 253.0
PYH2_k127_8962831_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.158e-206 650.0
PYH2_k127_8962831_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000032 135.0
PYH2_k127_8974160_0 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 449.0
PYH2_k127_8974160_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 413.0
PYH2_k127_8974160_2 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000009917 199.0
PYH2_k127_8974160_3 - - - - 0.00000000000000000000000000000000000000000005523 168.0
PYH2_k127_8990893_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000005306 225.0
PYH2_k127_8990893_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000008957 221.0
PYH2_k127_8990893_2 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000006076 218.0
PYH2_k127_8990893_3 - - - - 0.00000000000000000000000000006109 124.0
PYH2_k127_8991218_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 440.0
PYH2_k127_8991218_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 418.0
PYH2_k127_8991218_10 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000019 205.0
PYH2_k127_8991218_11 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.00000000000000000000000000000000000000000001197 168.0
PYH2_k127_8991218_12 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.0000000000000000000000000000000001167 138.0
PYH2_k127_8991218_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000002696 120.0
PYH2_k127_8991218_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000005632 105.0
PYH2_k127_8991218_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 412.0
PYH2_k127_8991218_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 385.0
PYH2_k127_8991218_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 380.0
PYH2_k127_8991218_5 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 364.0
PYH2_k127_8991218_6 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 365.0
PYH2_k127_8991218_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
PYH2_k127_8991218_8 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 336.0
PYH2_k127_8991218_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
PYH2_k127_8993456_0 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 533.0
PYH2_k127_8993456_1 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
PYH2_k127_8993456_2 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000168 209.0
PYH2_k127_8993456_3 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000003389 115.0
PYH2_k127_8994966_0 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 319.0
PYH2_k127_8994966_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003451 257.0
PYH2_k127_8996745_0 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 435.0
PYH2_k127_8996745_1 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 376.0
PYH2_k127_8996745_2 Acyltransferase - - - 0.00000000000000000000000002462 124.0
PYH2_k127_9002136_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.785e-245 769.0
PYH2_k127_9002136_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 376.0
PYH2_k127_9002136_2 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004411 271.0
PYH2_k127_9002136_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000002025 249.0
PYH2_k127_9002136_4 - - - - 0.0000000000004585 70.0
PYH2_k127_9017441_0 PFAM Sulfatase - - - 0.0 1215.0
PYH2_k127_9017441_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.315e-285 882.0
PYH2_k127_9017441_2 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 464.0
PYH2_k127_9017441_3 protein conserved in bacteria K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 371.0
PYH2_k127_9017441_4 response regulator K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 338.0
PYH2_k127_9017441_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007438 286.0
PYH2_k127_9017441_6 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001679 257.0
PYH2_k127_9017441_7 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000002713 207.0
PYH2_k127_9017441_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000004653 171.0
PYH2_k127_9018699_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 558.0
PYH2_k127_9018699_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004688 256.0
PYH2_k127_9018699_2 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000005745 138.0
PYH2_k127_9018699_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000003113 123.0
PYH2_k127_9039145_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.439e-266 828.0
PYH2_k127_9039145_1 Amidohydrolase family - - - 7.186e-194 617.0
PYH2_k127_9039145_2 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 413.0
PYH2_k127_9039145_3 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
PYH2_k127_9039795_0 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 411.0
PYH2_k127_9039795_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 377.0
PYH2_k127_9039795_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 300.0
PYH2_k127_9039795_3 Amidohydrolase K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 264.0
PYH2_k127_9039795_4 CBS domain - - - 0.000000000000000000000000000000000000000000974 173.0
PYH2_k127_9039795_5 - - - - 0.0000000000000000000000001009 109.0
PYH2_k127_9039795_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000584 102.0
PYH2_k127_9040978_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.403e-287 890.0
PYH2_k127_9040978_1 homoserine dehydrogenase - - - 1.632e-210 662.0
PYH2_k127_9040978_10 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000001096 117.0
PYH2_k127_9040978_11 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000009105 83.0
PYH2_k127_9040978_12 low-complexity proteins - - - 0.0000000000000984 82.0
PYH2_k127_9040978_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 550.0
PYH2_k127_9040978_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 462.0
PYH2_k127_9040978_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 437.0
PYH2_k127_9040978_5 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 431.0
PYH2_k127_9040978_6 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 441.0
PYH2_k127_9040978_7 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 388.0
PYH2_k127_9040978_8 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
PYH2_k127_9040978_9 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000001489 208.0
PYH2_k127_9042946_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 463.0
PYH2_k127_9042946_1 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 312.0
PYH2_k127_9042946_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 308.0
PYH2_k127_9042946_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000002472 169.0
PYH2_k127_9046890_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.593e-309 955.0
PYH2_k127_9046890_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 264.0
PYH2_k127_9046890_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000006421 188.0
PYH2_k127_9046890_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000003081 96.0
PYH2_k127_9046890_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000004114 58.0
PYH2_k127_9053320_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 439.0
PYH2_k127_9053320_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 319.0
PYH2_k127_9060959_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 471.0
PYH2_k127_9060959_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000003526 207.0
PYH2_k127_9060959_2 Belongs to the P(II) protein family - - - 0.0000000004574 61.0
PYH2_k127_9060959_3 - - - - 0.0001777 46.0
PYH2_k127_9071466_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2354.0
PYH2_k127_9071466_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1287.0
PYH2_k127_9071466_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 560.0
PYH2_k127_9071466_11 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 562.0
PYH2_k127_9071466_12 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 520.0
PYH2_k127_9071466_13 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 503.0
PYH2_k127_9071466_14 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 528.0
PYH2_k127_9071466_15 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 478.0
PYH2_k127_9071466_16 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 439.0
PYH2_k127_9071466_17 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 433.0
PYH2_k127_9071466_18 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 439.0
PYH2_k127_9071466_19 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 367.0
PYH2_k127_9071466_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5e-324 1007.0
PYH2_k127_9071466_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 331.0
PYH2_k127_9071466_21 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
PYH2_k127_9071466_22 NAD dependent epimerase/dehydratase family K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
PYH2_k127_9071466_23 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
PYH2_k127_9071466_24 SMART cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000002088 229.0
PYH2_k127_9071466_25 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
PYH2_k127_9071466_26 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000001662 207.0
PYH2_k127_9071466_27 fimbrial biogenesis protein PilN K02663 - - 0.000000000000000000000000000000000000000000000000000000004603 209.0
PYH2_k127_9071466_28 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000006967 193.0
PYH2_k127_9071466_29 ferredoxin - - - 0.0000000000000000000000000000000000002399 141.0
PYH2_k127_9071466_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.435e-287 894.0
PYH2_k127_9071466_30 Inorganic ion transport and metabolism K06202 - - 0.00000000000000000000000000000526 131.0
PYH2_k127_9071466_31 Rubrerythrin - - - 0.00000000000000000000000000004071 133.0
PYH2_k127_9071466_32 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000001236 123.0
PYH2_k127_9071466_33 pilus assembly protein pilp K02665 - - 0.000000000000000000000002662 111.0
PYH2_k127_9071466_34 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000001787 87.0
PYH2_k127_9071466_35 Cytochrome c - - - 0.0000000000000959 74.0
PYH2_k127_9071466_36 ABC transporter substrate binding protein K01989 - - 0.0001024 46.0
PYH2_k127_9071466_4 Type 4 fimbrial biogenesis protein K02666 - - 9.287e-245 778.0
PYH2_k127_9071466_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.585e-239 747.0
PYH2_k127_9071466_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.201e-222 704.0
PYH2_k127_9071466_7 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 9.59e-211 669.0
PYH2_k127_9071466_8 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 7.386e-195 616.0
PYH2_k127_9071466_9 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 577.0
PYH2_k127_9092409_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 389.0
PYH2_k127_9092409_1 - - - - 0.0000000000000000000000000000000000000000000000000008821 191.0
PYH2_k127_9092409_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000158 164.0
PYH2_k127_9108505_0 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 317.0
PYH2_k127_9108505_1 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
PYH2_k127_9108505_2 Thioesterase superfamily protein - - - 0.000000000000000000000000162 112.0
PYH2_k127_9108505_3 Major Facilitator Superfamily - - - 0.000000000000318 73.0
PYH2_k127_9113476_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 398.0
PYH2_k127_9113476_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
PYH2_k127_9113476_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
PYH2_k127_9113476_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000006563 194.0
PYH2_k127_9113476_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000001596 168.0
PYH2_k127_9113476_5 Sh3 type 3 domain protein - - - 0.000000000000000000000000000785 121.0
PYH2_k127_9113476_6 - - - - 0.00001922 55.0
PYH2_k127_9145074_0 ribonuclease, Rne Rng family K08301 - - 3.659e-227 717.0
PYH2_k127_9145074_1 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 600.0
PYH2_k127_9145074_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 427.0
PYH2_k127_9145074_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 308.0
PYH2_k127_9145074_4 Maf-like protein K06287 - - 0.00000000000000000000000000000005821 127.0
PYH2_k127_9152421_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 485.0
PYH2_k127_9152421_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
PYH2_k127_9152421_2 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000133 146.0
PYH2_k127_9152421_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000001039 122.0
PYH2_k127_9152421_4 Protein of unknown function (DUF3306) - - - 0.0000000000000000000002721 108.0
PYH2_k127_9158138_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.923e-197 626.0
PYH2_k127_9158138_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 563.0
PYH2_k127_9158138_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007484 266.0
PYH2_k127_9158138_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008162 235.0
PYH2_k127_9158138_12 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000008411 213.0
PYH2_k127_9158138_13 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000003589 171.0
PYH2_k127_9158138_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 551.0
PYH2_k127_9158138_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 514.0
PYH2_k127_9158138_4 sulfite oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 432.0
PYH2_k127_9158138_5 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 390.0
PYH2_k127_9158138_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 376.0
PYH2_k127_9158138_7 Pfam:Kce - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 367.0
PYH2_k127_9158138_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 369.0
PYH2_k127_9158138_9 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 310.0
PYH2_k127_9163549_0 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 473.0
PYH2_k127_9163549_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 463.0
PYH2_k127_9163549_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000131 186.0
PYH2_k127_9163549_3 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.000003394 49.0
PYH2_k127_9184121_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 491.0
PYH2_k127_9184121_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 484.0
PYH2_k127_9184121_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000005839 82.0
PYH2_k127_9246122_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 426.0
PYH2_k127_9246122_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 399.0
PYH2_k127_9246122_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 395.0
PYH2_k127_9246122_3 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000001522 86.0
PYH2_k127_9249706_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1104.0
PYH2_k127_9249706_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.845e-212 665.0
PYH2_k127_9249706_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 436.0
PYH2_k127_9249706_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002731 267.0
PYH2_k127_9249706_4 lipid catabolic process - - - 0.00000000000000000000000000000000001919 152.0
PYH2_k127_9249706_5 Pfam Family of - - - 0.0000000000000000000000000000008676 141.0
PYH2_k127_9249706_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000002503 85.0
PYH2_k127_9249706_7 RNA recognition motif - - - 0.0002229 48.0
PYH2_k127_9249706_8 Peptidase M48 - - - 0.0002999 44.0
PYH2_k127_9259154_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 6.67e-209 662.0
PYH2_k127_9259154_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 595.0
PYH2_k127_9259154_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000006342 164.0
PYH2_k127_9259154_11 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000001395 118.0
PYH2_k127_9259154_2 Peptidase family M28 K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 500.0
PYH2_k127_9259154_3 fad dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 462.0
PYH2_k127_9259154_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 419.0
PYH2_k127_9259154_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 339.0
PYH2_k127_9259154_6 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 296.0
PYH2_k127_9259154_7 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000003633 218.0
PYH2_k127_9259154_8 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000009382 163.0
PYH2_k127_9259154_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000005054 160.0
PYH2_k127_9276632_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 522.0
PYH2_k127_9276632_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000003657 171.0
PYH2_k127_9276632_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000005313 121.0
PYH2_k127_9300284_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 420.0
PYH2_k127_9300284_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
PYH2_k127_9300284_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 356.0
PYH2_k127_9300284_3 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 289.0
PYH2_k127_9300284_4 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003501 274.0
PYH2_k127_9300284_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
PYH2_k127_9300284_6 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000006199 223.0
PYH2_k127_9317437_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 542.0
PYH2_k127_9317437_1 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000002975 75.0
PYH2_k127_9317437_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0003798 44.0
PYH2_k127_9321013_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.105e-267 830.0
PYH2_k127_9321013_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 2.737e-199 641.0
PYH2_k127_9321013_2 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 398.0
PYH2_k127_9321013_3 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 347.0
PYH2_k127_9321013_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000168 274.0
PYH2_k127_9321013_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000003138 213.0
PYH2_k127_9321013_6 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000001551 183.0
PYH2_k127_9321013_7 - - - - 0.0000000000000000000001564 113.0
PYH2_k127_9321013_8 - - - - 0.000000000000001515 87.0
PYH2_k127_9321551_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 332.0
PYH2_k127_9321551_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005396 252.0
PYH2_k127_9321551_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000001344 141.0
PYH2_k127_940245_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.566e-255 807.0
PYH2_k127_940245_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 607.0
PYH2_k127_940245_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 540.0
PYH2_k127_940245_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 442.0
PYH2_k127_940245_4 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 331.0
PYH2_k127_940245_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
PYH2_k127_940245_6 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000003081 180.0
PYH2_k127_940245_7 PFAM HD domain - - - 0.000000004091 69.0
PYH2_k127_997066_0 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
PYH2_k127_997066_1 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000002404 236.0
PYH2_k127_997066_2 - - - - 0.00000000000000000000000000000000000000000000000000000001796 216.0
PYH2_k127_997066_3 BolA-like protein K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.0000000000000000001807 100.0
PYH2_k127_997066_4 Transglutaminase/protease-like homologues - - - 0.00000000000000004007 83.0
PYH2_k127_997066_5 ADP-D-ribose binding K15261 - 2.4.2.30 0.0000000005323 64.0