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Overview

ID MAG03180
Name PYH2_bin.21
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAKOQB01
Species
Assembly information
Completeness (%) 98.88
Contamination (%) 0.18
GC content (%) 64.0
N50 (bp) 18,342
Genome size (bp) 4,189,197

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4124

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1008628_0 oxidoreductase K04090 - 1.2.7.8 1e-203 646.0
PYH2_k127_1008628_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 582.0
PYH2_k127_1008628_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 499.0
PYH2_k127_1008628_3 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
PYH2_k127_1008628_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004669 231.0
PYH2_k127_1008628_5 Glycine cleavage H-protein - - - 0.0000000000000000000000001716 112.0
PYH2_k127_1008628_6 DsrE/DsrF-like family - - - 0.0000000000000003111 83.0
PYH2_k127_1008628_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000001025 56.0
PYH2_k127_1008628_8 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.000003785 59.0
PYH2_k127_1023556_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.389e-225 717.0
PYH2_k127_1023556_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 314.0
PYH2_k127_1023556_2 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000002289 133.0
PYH2_k127_1023556_3 Mitomycin resistance protein K07343 - - 0.0000000000000000000005354 104.0
PYH2_k127_1023556_4 regulator - - - 0.0000000002982 69.0
PYH2_k127_1047441_0 orn lys arg decarboxylase K01583 - 4.1.1.19 0.0 1369.0
PYH2_k127_1047441_1 Protein of unknown function (DUF3141) - - - 0.0 1068.0
PYH2_k127_1047441_10 Coenzyme A transferase K01035 - 2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 346.0
PYH2_k127_1047441_11 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 336.0
PYH2_k127_1047441_12 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
PYH2_k127_1047441_13 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000001017 194.0
PYH2_k127_1047441_14 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000001235 183.0
PYH2_k127_1047441_15 long-chain fatty acid transport protein - - - 0.000000000002971 72.0
PYH2_k127_1047441_16 - - - - 0.00000001472 55.0
PYH2_k127_1047441_17 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000314 48.0
PYH2_k127_1047441_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 557.0
PYH2_k127_1047441_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 551.0
PYH2_k127_1047441_4 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 537.0
PYH2_k127_1047441_5 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 507.0
PYH2_k127_1047441_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 440.0
PYH2_k127_1047441_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 407.0
PYH2_k127_1047441_8 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 388.0
PYH2_k127_1047441_9 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 351.0
PYH2_k127_1055282_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 4.761e-284 881.0
PYH2_k127_1055282_1 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 5.967e-264 825.0
PYH2_k127_1055282_10 Amino-transferase class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 351.0
PYH2_k127_1055282_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 298.0
PYH2_k127_1055282_12 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
PYH2_k127_1055282_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 258.0
PYH2_k127_1055282_14 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006723 237.0
PYH2_k127_1055282_15 COGs COG1569 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000000000000003943 167.0
PYH2_k127_1055282_16 - - - - 0.0000000000000000000000000000000000001576 147.0
PYH2_k127_1055282_17 PFAM SpoVT AbrB - - - 0.000000000000000000000000000006833 120.0
PYH2_k127_1055282_18 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000000008444 102.0
PYH2_k127_1055282_2 formate dehydrogenase K00123 - 1.17.1.9 9.534e-258 799.0
PYH2_k127_1055282_3 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 3.411e-229 719.0
PYH2_k127_1055282_4 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 557.0
PYH2_k127_1055282_5 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 511.0
PYH2_k127_1055282_6 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 498.0
PYH2_k127_1055282_7 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
PYH2_k127_1055282_8 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 435.0
PYH2_k127_1055282_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 373.0
PYH2_k127_1068039_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 349.0
PYH2_k127_1089417_0 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 286.0
PYH2_k127_1089417_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001312 276.0
PYH2_k127_1089417_10 peptidase - - - 0.000000000007652 66.0
PYH2_k127_1089417_11 peptidase - - - 0.0000000495 62.0
PYH2_k127_1089417_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000778 261.0
PYH2_k127_1089417_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000007369 180.0
PYH2_k127_1089417_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000001116 172.0
PYH2_k127_1089417_5 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000001292 143.0
PYH2_k127_1089417_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000001499 129.0
PYH2_k127_1089417_7 Transcriptional regulator - - - 0.0000000000000000000000000000009303 125.0
PYH2_k127_1089417_8 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000002857 124.0
PYH2_k127_1089417_9 - - - - 0.000000000000000002091 85.0
PYH2_k127_1099830_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 3.427e-287 897.0
PYH2_k127_1099830_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.195e-259 817.0
PYH2_k127_1099830_10 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000265 93.0
PYH2_k127_1099830_11 HEPN domain - - - 0.00000000000000005126 87.0
PYH2_k127_1099830_12 thiolester hydrolase activity K17362 - - 0.0000000001172 68.0
PYH2_k127_1099830_13 LemA family - - - 0.00007875 48.0
PYH2_k127_1099830_2 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 437.0
PYH2_k127_1099830_3 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 433.0
PYH2_k127_1099830_4 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000005453 251.0
PYH2_k127_1099830_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007962 242.0
PYH2_k127_1099830_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000002533 183.0
PYH2_k127_1099830_7 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000000000001095 145.0
PYH2_k127_1099830_8 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000001508 113.0
PYH2_k127_1099830_9 PFAM Small Multidrug Resistance protein K03297 - - 0.00000000000000000000003446 109.0
PYH2_k127_1114431_0 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 572.0
PYH2_k127_1114431_1 Polysaccharide biosynthesis protein - - - 0.00005153 47.0
PYH2_k127_1122936_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.405e-270 846.0
PYH2_k127_1122936_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 383.0
PYH2_k127_1122936_2 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 342.0
PYH2_k127_1122936_3 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000008729 200.0
PYH2_k127_1122936_4 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000004475 110.0
PYH2_k127_1122936_5 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000000000000001062 92.0
PYH2_k127_1122936_6 protein conserved in bacteria - - - 0.000000000000009297 77.0
PYH2_k127_1152751_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.848e-306 952.0
PYH2_k127_1152751_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 572.0
PYH2_k127_1152751_10 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
PYH2_k127_1152751_11 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000005273 191.0
PYH2_k127_1152751_12 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000007192 171.0
PYH2_k127_1152751_13 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000005867 158.0
PYH2_k127_1152751_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001426 108.0
PYH2_k127_1152751_16 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.00000000000000002947 84.0
PYH2_k127_1152751_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 520.0
PYH2_k127_1152751_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 483.0
PYH2_k127_1152751_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
PYH2_k127_1152751_5 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 446.0
PYH2_k127_1152751_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 364.0
PYH2_k127_1152751_7 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 351.0
PYH2_k127_1152751_8 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 340.0
PYH2_k127_1152751_9 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 289.0
PYH2_k127_1161846_0 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001951 265.0
PYH2_k127_1161846_1 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000009055 217.0
PYH2_k127_1161846_2 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000000001064 80.0
PYH2_k127_1161846_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0003713 50.0
PYH2_k127_1165553_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 413.0
PYH2_k127_1165553_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 406.0
PYH2_k127_1165553_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 397.0
PYH2_k127_1165553_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000001286 145.0
PYH2_k127_1190083_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 282.0
PYH2_k127_1190083_1 - - - - 0.0000000000000000000008952 109.0
PYH2_k127_1192035_0 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 542.0
PYH2_k127_1192035_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 425.0
PYH2_k127_1192035_2 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003352 297.0
PYH2_k127_1192035_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
PYH2_k127_1192035_4 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000004675 124.0
PYH2_k127_1192035_5 Domain of unknown function (DUF4124) - - - 0.0002306 49.0
PYH2_k127_1213012_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 544.0
PYH2_k127_1213012_1 IS66 C-terminal element - - - 0.00000000000002613 81.0
PYH2_k127_1215605_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 302.0
PYH2_k127_1215605_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003867 260.0
PYH2_k127_1215605_2 Cytochrome c - - - 0.0000000000000000000000000000000003137 145.0
PYH2_k127_1215605_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000003355 102.0
PYH2_k127_1225801_0 Belongs to the glycosyl hydrolase family 6 - - - 9.946e-240 760.0
PYH2_k127_1225801_1 Transposase DDE domain - - - 6.576e-222 705.0
PYH2_k127_1249202_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.968e-256 813.0
PYH2_k127_1249202_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 470.0
PYH2_k127_1249202_10 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000166 248.0
PYH2_k127_1249202_11 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
PYH2_k127_1249202_12 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000003567 205.0
PYH2_k127_1249202_13 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000001056 169.0
PYH2_k127_1249202_14 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000002532 131.0
PYH2_k127_1249202_15 - - - - 0.0000000000000000000000000007444 119.0
PYH2_k127_1249202_2 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 462.0
PYH2_k127_1249202_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 427.0
PYH2_k127_1249202_4 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
PYH2_k127_1249202_5 coenzyme F420-1:gamma-L-glutamate ligase activity K19285,K19286 - 1.5.1.38,1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
PYH2_k127_1249202_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 327.0
PYH2_k127_1249202_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 294.0
PYH2_k127_1249202_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
PYH2_k127_1249202_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000005626 250.0
PYH2_k127_1293022_0 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 396.0
PYH2_k127_1293022_1 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000003604 150.0
PYH2_k127_1293022_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000004404 90.0
PYH2_k127_1302183_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 6.708e-202 638.0
PYH2_k127_1302183_1 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 539.0
PYH2_k127_1302183_10 YHS domain protein - - - 0.00000000000000000000000000000000004303 141.0
PYH2_k127_1302183_11 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000001516 139.0
PYH2_k127_1302183_12 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000004413 124.0
PYH2_k127_1302183_2 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
PYH2_k127_1302183_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 357.0
PYH2_k127_1302183_4 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
PYH2_k127_1302183_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001215 249.0
PYH2_k127_1302183_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
PYH2_k127_1302183_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000004433 203.0
PYH2_k127_1302183_8 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000004678 171.0
PYH2_k127_1310412_0 Tricorn protease homolog K08676 - - 0.0 1104.0
PYH2_k127_1310412_1 Male sterility protein - - - 0.0 1005.0
PYH2_k127_1310412_10 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
PYH2_k127_1310412_11 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 430.0
PYH2_k127_1310412_12 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 398.0
PYH2_k127_1310412_13 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 366.0
PYH2_k127_1310412_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 345.0
PYH2_k127_1310412_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 323.0
PYH2_k127_1310412_16 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 324.0
PYH2_k127_1310412_17 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 326.0
PYH2_k127_1310412_18 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
PYH2_k127_1310412_19 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 319.0
PYH2_k127_1310412_2 ABC-type Fe3 transport system permease component K02011 - - 2.159e-250 788.0
PYH2_k127_1310412_20 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
PYH2_k127_1310412_21 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001766 269.0
PYH2_k127_1310412_22 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005522 268.0
PYH2_k127_1310412_23 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
PYH2_k127_1310412_24 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008718 252.0
PYH2_k127_1310412_25 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH2_k127_1310412_26 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000002359 209.0
PYH2_k127_1310412_27 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000004909 200.0
PYH2_k127_1310412_28 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000002097 179.0
PYH2_k127_1310412_29 PFAM poly granule associated family protein - - - 0.000000000000000000000000000000000000002323 152.0
PYH2_k127_1310412_3 Branched-chain amino acid transport system / permease component K01997,K01998 - - 5.096e-211 672.0
PYH2_k127_1310412_30 acyl-coA-binding protein - - - 0.000000000000000000000000000000000322 134.0
PYH2_k127_1310412_31 - - - - 0.000000000000000000000004775 111.0
PYH2_k127_1310412_32 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000001207 86.0
PYH2_k127_1310412_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 6.349e-203 640.0
PYH2_k127_1310412_5 ABC-type Fe3 transport system, periplasmic component - - - 5.145e-196 620.0
PYH2_k127_1310412_6 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 601.0
PYH2_k127_1310412_7 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 592.0
PYH2_k127_1310412_8 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 549.0
PYH2_k127_1310412_9 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 499.0
PYH2_k127_1328219_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 1.405e-207 664.0
PYH2_k127_1328219_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 549.0
PYH2_k127_1328219_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003642 259.0
PYH2_k127_1328219_11 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000001013 199.0
PYH2_k127_1328219_12 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000001542 191.0
PYH2_k127_1328219_13 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001953 169.0
PYH2_k127_1328219_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002927 166.0
PYH2_k127_1328219_15 - - - - 0.00000000000000000000000000000000000000001691 164.0
PYH2_k127_1328219_16 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000001278 155.0
PYH2_k127_1328219_17 acetyltransferase - - - 0.000000000000000000000000000000000001748 144.0
PYH2_k127_1328219_18 Rubrerythrin - - - 0.0000000000000000000000000000000000222 148.0
PYH2_k127_1328219_19 PFAM glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000002584 119.0
PYH2_k127_1328219_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 534.0
PYH2_k127_1328219_20 DUF167 K09131 - - 0.000000000000000001188 88.0
PYH2_k127_1328219_22 SnoaL-like domain - - - 0.000000008645 61.0
PYH2_k127_1328219_23 MacB-like periplasmic core domain K02004 - - 0.0001224 52.0
PYH2_k127_1328219_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 537.0
PYH2_k127_1328219_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 446.0
PYH2_k127_1328219_5 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
PYH2_k127_1328219_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 362.0
PYH2_k127_1328219_7 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
PYH2_k127_1328219_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
PYH2_k127_1328219_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006353 285.0
PYH2_k127_1342053_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 376.0
PYH2_k127_1342053_1 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 313.0
PYH2_k127_1342053_2 transporter arsB - - - 0.0002295 48.0
PYH2_k127_1399194_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 1.869e-235 742.0
PYH2_k127_1399194_1 FAD dependent oxidoreductase - - - 5.618e-206 647.0
PYH2_k127_1399194_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.478e-195 615.0
PYH2_k127_1399194_3 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 516.0
PYH2_k127_1399194_4 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000001155 79.0
PYH2_k127_1399194_5 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0009163 43.0
PYH2_k127_1425138_0 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 542.0
PYH2_k127_1425138_1 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 536.0
PYH2_k127_1425138_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 509.0
PYH2_k127_1425138_3 PFAM Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.000000000000003342 76.0
PYH2_k127_1425138_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000001886 55.0
PYH2_k127_143025_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1308.0
PYH2_k127_143025_1 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
PYH2_k127_143025_2 PQ loop repeat K15383 - - 0.000000000000000000008115 94.0
PYH2_k127_1465850_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.494e-276 860.0
PYH2_k127_1465850_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.868e-262 833.0
PYH2_k127_1465850_10 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 491.0
PYH2_k127_1465850_11 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 469.0
PYH2_k127_1465850_12 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 437.0
PYH2_k127_1465850_13 succinylglutamate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 411.0
PYH2_k127_1465850_14 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 411.0
PYH2_k127_1465850_15 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
PYH2_k127_1465850_16 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
PYH2_k127_1465850_17 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 288.0
PYH2_k127_1465850_18 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 281.0
PYH2_k127_1465850_19 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006564 243.0
PYH2_k127_1465850_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.618e-227 711.0
PYH2_k127_1465850_20 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000001535 246.0
PYH2_k127_1465850_21 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
PYH2_k127_1465850_22 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
PYH2_k127_1465850_23 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000001623 162.0
PYH2_k127_1465850_24 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000007439 138.0
PYH2_k127_1465850_25 ThiS family K03636 - - 0.000000000000000000000000000000006969 128.0
PYH2_k127_1465850_26 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000004039 130.0
PYH2_k127_1465850_27 membrane K08972 - - 0.0000000000000000000000000000001311 129.0
PYH2_k127_1465850_28 CoA binding domain - - - 0.0000000000000000000000000000009727 130.0
PYH2_k127_1465850_29 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000005529 86.0
PYH2_k127_1465850_3 protein related to plant photosystem II stability assembly factor - - - 1.632e-218 683.0
PYH2_k127_1465850_30 acyltransferase K02517 - 2.3.1.241 0.000000000000006163 78.0
PYH2_k127_1465850_31 - - - - 0.00001909 53.0
PYH2_k127_1465850_4 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 589.0
PYH2_k127_1465850_5 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 565.0
PYH2_k127_1465850_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 560.0
PYH2_k127_1465850_7 Soluble lytic murein K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 569.0
PYH2_k127_1465850_8 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 526.0
PYH2_k127_1465850_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 506.0
PYH2_k127_1472674_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 576.0
PYH2_k127_1472674_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 497.0
PYH2_k127_1472674_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 411.0
PYH2_k127_1472674_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 348.0
PYH2_k127_1472674_4 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
PYH2_k127_1472674_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000001624 189.0
PYH2_k127_1472674_6 TPR repeat - - - 0.0000000000000000001822 91.0
PYH2_k127_1563065_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1430.0
PYH2_k127_1563065_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.167e-244 773.0
PYH2_k127_1563065_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 379.0
PYH2_k127_1563065_11 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 294.0
PYH2_k127_1563065_12 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002213 285.0
PYH2_k127_1563065_13 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
PYH2_k127_1563065_14 ABC transporter permease K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
PYH2_k127_1563065_15 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002068 256.0
PYH2_k127_1563065_16 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
PYH2_k127_1563065_17 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
PYH2_k127_1563065_18 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
PYH2_k127_1563065_19 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
PYH2_k127_1563065_2 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 608.0
PYH2_k127_1563065_20 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000007012 192.0
PYH2_k127_1563065_21 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000001466 151.0
PYH2_k127_1563065_22 sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000006646 133.0
PYH2_k127_1563065_23 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000005533 131.0
PYH2_k127_1563065_24 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000001765 116.0
PYH2_k127_1563065_25 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000002264 57.0
PYH2_k127_1563065_26 Tetratricopeptide repeat - - - 0.000005176 59.0
PYH2_k127_1563065_3 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 593.0
PYH2_k127_1563065_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 545.0
PYH2_k127_1563065_5 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 520.0
PYH2_k127_1563065_6 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 503.0
PYH2_k127_1563065_7 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 420.0
PYH2_k127_1563065_8 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 420.0
PYH2_k127_1563065_9 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
PYH2_k127_1579390_0 TRAP dicarboxylate transporter, DctM subunit K11690 - - 1.234e-208 656.0
PYH2_k127_1579390_1 TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 492.0
PYH2_k127_1579390_2 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
PYH2_k127_1579390_3 Cyclase dehydrase - - - 0.000000000000000000000000000000000000002239 159.0
PYH2_k127_1579390_4 - - - - 0.00000000000000000000006779 100.0
PYH2_k127_1604969_0 FAD dependent oxidoreductase central domain - - - 0.0 1357.0
PYH2_k127_1604969_1 Peptidase M61 - - - 1.335e-213 679.0
PYH2_k127_1604969_10 Histone methylation protein DOT1 - - - 0.0000002405 55.0
PYH2_k127_1604969_2 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 513.0
PYH2_k127_1604969_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
PYH2_k127_1604969_4 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 417.0
PYH2_k127_1604969_5 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 390.0
PYH2_k127_1604969_6 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000004316 179.0
PYH2_k127_1604969_7 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000002138 168.0
PYH2_k127_1604969_8 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000008707 82.0
PYH2_k127_1604969_9 - - - - 0.0000000005803 68.0
PYH2_k127_1641911_0 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 398.0
PYH2_k127_1641911_1 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 379.0
PYH2_k127_1641911_2 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 376.0
PYH2_k127_1657955_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 528.0
PYH2_k127_1657955_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 462.0
PYH2_k127_1657955_2 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 319.0
PYH2_k127_1657955_3 tetR family - - - 0.0000000000000000000000000000000000000000000000000001393 190.0
PYH2_k127_1709832_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.439e-201 631.0
PYH2_k127_1709832_1 TAP-like protein K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 547.0
PYH2_k127_1709832_10 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005195 245.0
PYH2_k127_1709832_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009238 235.0
PYH2_k127_1709832_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
PYH2_k127_1709832_13 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000007975 220.0
PYH2_k127_1709832_14 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000000000000000005671 173.0
PYH2_k127_1709832_2 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 505.0
PYH2_k127_1709832_3 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
PYH2_k127_1709832_4 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 448.0
PYH2_k127_1709832_5 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 404.0
PYH2_k127_1709832_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 398.0
PYH2_k127_1709832_7 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 362.0
PYH2_k127_1709832_8 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 364.0
PYH2_k127_1709832_9 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 327.0
PYH2_k127_1749594_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.767e-282 880.0
PYH2_k127_1749594_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 2.911e-200 640.0
PYH2_k127_1749594_10 positive regulation of growth - - - 0.00000003136 59.0
PYH2_k127_1749594_11 Cytochrome c - - - 0.0000004377 55.0
PYH2_k127_1749594_2 SMART extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
PYH2_k127_1749594_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003315 265.0
PYH2_k127_1749594_4 Aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000001825 233.0
PYH2_k127_1749594_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001813 214.0
PYH2_k127_1749594_6 DNA-binding - - - 0.000000000000000000000000000000000000000000000000000004334 196.0
PYH2_k127_1749594_7 - - - - 0.000000000000000000000000000000000000001319 150.0
PYH2_k127_1749594_8 PIN domain - - - 0.0000000000000000000000000001097 121.0
PYH2_k127_1749594_9 Cytochrome c - - - 0.000000001428 59.0
PYH2_k127_1822591_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 483.0
PYH2_k127_1822591_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004332 240.0
PYH2_k127_1822591_2 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000002002 168.0
PYH2_k127_1822591_3 Histidine kinase - - - 0.000000000000000000004341 95.0
PYH2_k127_1822834_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.487e-293 907.0
PYH2_k127_1822834_1 - - - - 0.000000000002801 68.0
PYH2_k127_1872781_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1110.0
PYH2_k127_1872781_1 GTP-binding protein K06207 - - 0.0 1018.0
PYH2_k127_1872781_2 Participates in both transcription termination and antitermination K02600 - - 5.116e-212 669.0
PYH2_k127_1872781_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
PYH2_k127_1872781_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000226 290.0
PYH2_k127_1872781_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000001406 216.0
PYH2_k127_1872781_6 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000005328 180.0
PYH2_k127_1872781_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000002619 164.0
PYH2_k127_1872781_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000103 171.0
PYH2_k127_1890482_0 General function prediction only K06020 - 3.6.3.25 4.65e-290 897.0
PYH2_k127_1890482_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000002665 194.0
PYH2_k127_1895804_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 474.0
PYH2_k127_1895804_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 390.0
PYH2_k127_1895804_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005148 212.0
PYH2_k127_1895804_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000004078 216.0
PYH2_k127_1929915_0 Fe-S oxidoreductase K21834 - - 1.315e-275 867.0
PYH2_k127_1929915_1 NADPH-dependent glutamate synthase beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 370.0
PYH2_k127_1929915_2 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 326.0
PYH2_k127_1929915_3 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000001669 120.0
PYH2_k127_1932003_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
PYH2_k127_1932003_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000003179 192.0
PYH2_k127_195407_0 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 440.0
PYH2_k127_195407_1 transcriptional regulator - - - 0.000000000000000000000000000000000001039 151.0
PYH2_k127_195407_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000518 72.0
PYH2_k127_195407_3 Kelch - - - 0.000000001607 62.0
PYH2_k127_195407_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0003683 45.0
PYH2_k127_1987925_0 Dehydratase family K13875 - 4.2.1.25 2.412e-250 778.0
PYH2_k127_1987925_1 Bacterial extracellular solute-binding protein K02027 - - 4.92e-216 677.0
PYH2_k127_1987925_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
PYH2_k127_1987925_3 ABC-type sugar K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 497.0
PYH2_k127_1987925_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 431.0
PYH2_k127_1987925_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000002369 74.0
PYH2_k127_1994216_0 Sulfate transporter antisigma-factor antagonist STAS - - - 2.724e-272 844.0
PYH2_k127_1994216_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 293.0
PYH2_k127_2023912_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.788e-228 727.0
PYH2_k127_2023912_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 617.0
PYH2_k127_2023912_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 536.0
PYH2_k127_2023912_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 458.0
PYH2_k127_2023912_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
PYH2_k127_2023912_5 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 287.0
PYH2_k127_2023912_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
PYH2_k127_2023912_7 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001557 262.0
PYH2_k127_2023912_8 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
PYH2_k127_2023912_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000006281 184.0
PYH2_k127_203025_0 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 345.0
PYH2_k127_203025_1 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000004339 212.0
PYH2_k127_203025_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000006215 103.0
PYH2_k127_203025_3 lipolytic protein G-D-S-L family - - - 0.00000000000000001082 96.0
PYH2_k127_203025_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000005797 60.0
PYH2_k127_2099221_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.456e-299 934.0
PYH2_k127_2099221_1 AMP-binding enzyme K00666 - - 8.356e-298 924.0
PYH2_k127_2099221_10 Transcriptional regulator K04033 - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
PYH2_k127_2099221_11 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000001739 170.0
PYH2_k127_2099221_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000001051 150.0
PYH2_k127_2099221_13 COG3209 Rhs family protein - - - 0.00000000000000000000000000002467 131.0
PYH2_k127_2099221_14 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000001468 102.0
PYH2_k127_2099221_15 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000001615 98.0
PYH2_k127_2099221_16 NADH ubiquinone plastoquinone (Complex I) - - - 0.0000000000000000000005942 98.0
PYH2_k127_2099221_17 - - - - 0.0000000000000000000519 98.0
PYH2_k127_2099221_18 Domain of unknown function (DUF1330) - - - 0.00000000006321 67.0
PYH2_k127_2099221_19 aspartyl asparaginyl K12979 - - 0.0001516 48.0
PYH2_k127_2099221_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 1.483e-205 653.0
PYH2_k127_2099221_3 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 598.0
PYH2_k127_2099221_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 591.0
PYH2_k127_2099221_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 538.0
PYH2_k127_2099221_6 Histidine kinase K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 459.0
PYH2_k127_2099221_7 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 420.0
PYH2_k127_2099221_8 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 341.0
PYH2_k127_2099221_9 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 325.0
PYH2_k127_2106109_0 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 461.0
PYH2_k127_2106109_1 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
PYH2_k127_2106109_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000002289 196.0
PYH2_k127_2106109_3 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000000000000001238 84.0
PYH2_k127_2161948_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 2.18e-278 865.0
PYH2_k127_2161948_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.258e-215 677.0
PYH2_k127_2161948_2 Dehydrogenase K15515 - 1.2.1.81 1.664e-208 657.0
PYH2_k127_2161948_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 490.0
PYH2_k127_2161948_4 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003353 283.0
PYH2_k127_2161948_5 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000002169 185.0
PYH2_k127_2161948_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000002888 156.0
PYH2_k127_2211241_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1138.0
PYH2_k127_2211241_1 ABC transporter transmembrane region K06147 - - 2.249e-264 826.0
PYH2_k127_2211241_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 567.0
PYH2_k127_2211241_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 565.0
PYH2_k127_2211241_12 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 546.0
PYH2_k127_2211241_13 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 543.0
PYH2_k127_2211241_14 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 525.0
PYH2_k127_2211241_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 505.0
PYH2_k127_2211241_16 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 501.0
PYH2_k127_2211241_17 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 482.0
PYH2_k127_2211241_18 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 449.0
PYH2_k127_2211241_19 Outer membrane protein beta-barrel family K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 453.0
PYH2_k127_2211241_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 5.216e-254 795.0
PYH2_k127_2211241_20 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 436.0
PYH2_k127_2211241_21 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 410.0
PYH2_k127_2211241_22 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 392.0
PYH2_k127_2211241_23 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 388.0
PYH2_k127_2211241_24 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
PYH2_k127_2211241_25 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 360.0
PYH2_k127_2211241_26 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 355.0
PYH2_k127_2211241_27 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 351.0
PYH2_k127_2211241_28 COG3293 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 328.0
PYH2_k127_2211241_29 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004908 283.0
PYH2_k127_2211241_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.277e-219 687.0
PYH2_k127_2211241_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001616 272.0
PYH2_k127_2211241_31 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
PYH2_k127_2211241_33 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000004628 225.0
PYH2_k127_2211241_34 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000000187 199.0
PYH2_k127_2211241_35 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
PYH2_k127_2211241_36 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000114 189.0
PYH2_k127_2211241_37 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000002589 182.0
PYH2_k127_2211241_38 - - - - 0.0000000000000000000000000000000000000000007047 166.0
PYH2_k127_2211241_39 Histidine kinase - - - 0.000000000000000000000000000000001766 133.0
PYH2_k127_2211241_4 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 6.071e-217 688.0
PYH2_k127_2211241_40 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000376 131.0
PYH2_k127_2211241_41 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000001291 131.0
PYH2_k127_2211241_42 flagellar protein FliS K02422 - - 0.000000000000000000000000000002619 125.0
PYH2_k127_2211241_43 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000001047 93.0
PYH2_k127_2211241_44 Flagellar protein FliT K02423 - - 0.000000000000000001987 92.0
PYH2_k127_2211241_45 Aldo/keto reductase family - - - 0.0000000000000009428 78.0
PYH2_k127_2211241_46 - - - - 0.00000000000004258 81.0
PYH2_k127_2211241_47 Membrane - - - 0.000000000001864 76.0
PYH2_k127_2211241_48 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000001467 71.0
PYH2_k127_2211241_49 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000007652 72.0
PYH2_k127_2211241_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.627e-208 654.0
PYH2_k127_2211241_50 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000007785 61.0
PYH2_k127_2211241_51 Flagellar regulator YcgR - - - 0.00000002731 64.0
PYH2_k127_2211241_52 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000001756 53.0
PYH2_k127_2211241_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 606.0
PYH2_k127_2211241_7 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 604.0
PYH2_k127_2211241_8 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 578.0
PYH2_k127_2211241_9 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 580.0
PYH2_k127_2214315_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 581.0
PYH2_k127_2214315_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 510.0
PYH2_k127_2214315_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
PYH2_k127_2214315_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 302.0
PYH2_k127_2214315_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 291.0
PYH2_k127_2214315_5 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000001242 212.0
PYH2_k127_2214315_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000003975 182.0
PYH2_k127_2214315_7 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000001452 155.0
PYH2_k127_2214315_8 Histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000001193 159.0
PYH2_k127_2214315_9 - - - - 0.00000000000000000002129 100.0
PYH2_k127_2217382_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 586.0
PYH2_k127_2217382_1 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 384.0
PYH2_k127_2217382_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 381.0
PYH2_k127_2217382_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 342.0
PYH2_k127_2217382_4 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000001455 221.0
PYH2_k127_2217382_5 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000006287 198.0
PYH2_k127_2217382_6 PFAM PsiF repeat protein - - - 0.000000000000000000001048 98.0
PYH2_k127_2231469_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1624.0
PYH2_k127_2231469_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 4.863e-239 746.0
PYH2_k127_2231469_10 periplasmic K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 483.0
PYH2_k127_2231469_11 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
PYH2_k127_2231469_12 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 387.0
PYH2_k127_2231469_13 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 377.0
PYH2_k127_2231469_14 Pfam Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
PYH2_k127_2231469_15 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 321.0
PYH2_k127_2231469_16 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
PYH2_k127_2231469_17 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 316.0
PYH2_k127_2231469_18 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
PYH2_k127_2231469_19 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
PYH2_k127_2231469_2 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.491e-225 699.0
PYH2_k127_2231469_20 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005605 269.0
PYH2_k127_2231469_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005404 260.0
PYH2_k127_2231469_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH2_k127_2231469_23 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000619 205.0
PYH2_k127_2231469_24 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000001047 203.0
PYH2_k127_2231469_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001057 179.0
PYH2_k127_2231469_26 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000003176 156.0
PYH2_k127_2231469_27 Plasmid stabilization system K19092 - - 0.000000000000000000000000000000000000000007529 159.0
PYH2_k127_2231469_28 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000001566 126.0
PYH2_k127_2231469_29 PIN domain - - - 0.0000000000000000000000000000007552 126.0
PYH2_k127_2231469_3 MmgE PrpD family protein - - - 1.505e-207 654.0
PYH2_k127_2231469_30 Dodecin K09165 - - 0.00000000000000000000000000008703 117.0
PYH2_k127_2231469_31 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000015 115.0
PYH2_k127_2231469_32 - - - - 0.00000000000000000000000003967 113.0
PYH2_k127_2231469_33 - - - - 0.00000000000000000000002326 108.0
PYH2_k127_2231469_34 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000004486 91.0
PYH2_k127_2231469_35 membrane organization - - - 0.0000000000000000009543 91.0
PYH2_k127_2231469_36 mRNA binding K07339 - - 0.000000000000000002989 89.0
PYH2_k127_2231469_37 Domain of unknown function (DUF4160) - - - 0.000000000000000008231 84.0
PYH2_k127_2231469_38 Protein of unknown function (DUF2783) - - - 0.0000000000000006719 79.0
PYH2_k127_2231469_39 Protein of unknown function (DUF2442) - - - 0.000000000000003879 78.0
PYH2_k127_2231469_4 CoA-transferase family III K18289 - 2.8.3.22 4.308e-195 625.0
PYH2_k127_2231469_40 Domain of unknown function (DUF4160) - - - 0.0000001962 52.0
PYH2_k127_2231469_42 - - - - 0.000004329 51.0
PYH2_k127_2231469_43 protein import - - - 0.00001675 50.0
PYH2_k127_2231469_44 - - - - 0.00002289 54.0
PYH2_k127_2231469_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 582.0
PYH2_k127_2231469_6 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 596.0
PYH2_k127_2231469_7 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
PYH2_k127_2231469_8 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 517.0
PYH2_k127_2231469_9 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 498.0
PYH2_k127_2235385_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.296e-208 653.0
PYH2_k127_2235385_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 385.0
PYH2_k127_2235385_2 - - - - 0.0000000000000000000000000000000000000000000000000000000145 201.0
PYH2_k127_2235385_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000004435 127.0
PYH2_k127_2312958_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1143.0
PYH2_k127_2312958_1 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 7.862e-213 685.0
PYH2_k127_2312958_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003131 259.0
PYH2_k127_2312958_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000005743 243.0
PYH2_k127_2312958_12 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001852 218.0
PYH2_k127_2312958_13 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000001395 192.0
PYH2_k127_2312958_14 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000001576 159.0
PYH2_k127_2312958_15 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000003992 147.0
PYH2_k127_2312958_16 response regulator - - - 0.00006446 47.0
PYH2_k127_2312958_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 610.0
PYH2_k127_2312958_3 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 567.0
PYH2_k127_2312958_4 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
PYH2_k127_2312958_5 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 363.0
PYH2_k127_2312958_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 356.0
PYH2_k127_2312958_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 339.0
PYH2_k127_2312958_8 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 301.0
PYH2_k127_2312958_9 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
PYH2_k127_2314675_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.635e-269 837.0
PYH2_k127_2314675_1 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 3.462e-243 762.0
PYH2_k127_2314675_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000002671 152.0
PYH2_k127_2314675_11 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000001542 147.0
PYH2_k127_2314675_12 nucleotidyltransferase activity - - - 0.000000000000000000000000000000004775 141.0
PYH2_k127_2314675_13 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000009877 108.0
PYH2_k127_2314675_14 Protein of unknown function DUF86 - - - 0.000000000000000000000001366 109.0
PYH2_k127_2314675_15 - - - - 0.00000000000000000000003431 104.0
PYH2_k127_2314675_2 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 5.536e-216 679.0
PYH2_k127_2314675_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 7.611e-213 677.0
PYH2_k127_2314675_4 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 464.0
PYH2_k127_2314675_5 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 415.0
PYH2_k127_2314675_6 coenzyme F390 synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 372.0
PYH2_k127_2314675_7 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 364.0
PYH2_k127_2314675_8 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000003952 226.0
PYH2_k127_2314675_9 AMP-binding enzyme K00666 - - 0.00000000000000000000000000000000000000000000000000001371 196.0
PYH2_k127_2367436_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.934e-210 662.0
PYH2_k127_2367436_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 580.0
PYH2_k127_2367436_10 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
PYH2_k127_2367436_11 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
PYH2_k127_2367436_12 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 364.0
PYH2_k127_2367436_13 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 337.0
PYH2_k127_2367436_14 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 328.0
PYH2_k127_2367436_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 316.0
PYH2_k127_2367436_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
PYH2_k127_2367436_17 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
PYH2_k127_2367436_18 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
PYH2_k127_2367436_19 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
PYH2_k127_2367436_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 563.0
PYH2_k127_2367436_20 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000002497 230.0
PYH2_k127_2367436_21 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000006253 213.0
PYH2_k127_2367436_22 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000002298 209.0
PYH2_k127_2367436_23 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000003291 192.0
PYH2_k127_2367436_24 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000006532 188.0
PYH2_k127_2367436_25 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000001708 181.0
PYH2_k127_2367436_26 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000003376 172.0
PYH2_k127_2367436_27 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000002369 147.0
PYH2_k127_2367436_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000009591 144.0
PYH2_k127_2367436_29 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000002352 123.0
PYH2_k127_2367436_3 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 451.0
PYH2_k127_2367436_30 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000002607 109.0
PYH2_k127_2367436_31 protein import - - - 0.00000000000000000003032 102.0
PYH2_k127_2367436_32 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000004843 93.0
PYH2_k127_2367436_33 NTP binding protein (Contains STAS domain) K04749,K07122 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716 - 0.000000000000004601 78.0
PYH2_k127_2367436_34 - - - - 0.00001857 51.0
PYH2_k127_2367436_35 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0003852 45.0
PYH2_k127_2367436_4 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 441.0
PYH2_k127_2367436_5 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 434.0
PYH2_k127_2367436_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 431.0
PYH2_k127_2367436_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 416.0
PYH2_k127_2367436_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 412.0
PYH2_k127_2367436_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 401.0
PYH2_k127_2381569_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1238.0
PYH2_k127_2381569_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 606.0
PYH2_k127_2381569_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 335.0
PYH2_k127_2381569_11 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000006488 238.0
PYH2_k127_2381569_13 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
PYH2_k127_2381569_14 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000002367 117.0
PYH2_k127_2381569_15 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000002548 73.0
PYH2_k127_2381569_16 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000138 67.0
PYH2_k127_2381569_17 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000351 61.0
PYH2_k127_2381569_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 572.0
PYH2_k127_2381569_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 565.0
PYH2_k127_2381569_4 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 529.0
PYH2_k127_2381569_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 469.0
PYH2_k127_2381569_6 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 450.0
PYH2_k127_2381569_7 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
PYH2_k127_2381569_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 398.0
PYH2_k127_2381569_9 binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 359.0
PYH2_k127_2406936_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.25e-206 650.0
PYH2_k127_2406936_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 583.0
PYH2_k127_2406936_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 458.0
PYH2_k127_2406936_3 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 336.0
PYH2_k127_2406936_4 Permease, YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 271.0
PYH2_k127_2406936_5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005946 253.0
PYH2_k127_2406936_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000056 199.0
PYH2_k127_2406936_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000003511 148.0
PYH2_k127_2406936_8 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000003663 130.0
PYH2_k127_2424627_0 Glucodextranase, domain N K01178 - 3.2.1.3 7.259e-305 950.0
PYH2_k127_2424627_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000005115 123.0
PYH2_k127_2450221_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 426.0
PYH2_k127_2450221_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 234.0
PYH2_k127_2450221_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000004042 199.0
PYH2_k127_2450221_3 - - - - 0.0000000000000000000000001922 109.0
PYH2_k127_2450221_4 YMGG-like Gly-zipper - - - 0.00000000000000626 81.0
PYH2_k127_2470365_0 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 579.0
PYH2_k127_2470365_1 von Willebrand factor (vWF) type A domain - - - 0.0005285 46.0
PYH2_k127_2515699_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 541.0
PYH2_k127_2515699_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 389.0
PYH2_k127_2515699_2 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000006246 107.0
PYH2_k127_2515699_3 - - - - 0.000000000000000000002913 102.0
PYH2_k127_2515699_4 - - - - 0.0000000000000001657 83.0
PYH2_k127_2521108_0 ABC transporter, ATP-binding protein K18893 - - 2.391e-230 719.0
PYH2_k127_2521108_1 Luciferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 472.0
PYH2_k127_2521108_10 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent K00480 - 1.14.13.1 0.0000008603 53.0
PYH2_k127_2521108_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 468.0
PYH2_k127_2521108_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 309.0
PYH2_k127_2521108_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003698 216.0
PYH2_k127_2521108_5 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000008593 204.0
PYH2_k127_2521108_6 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000002328 182.0
PYH2_k127_2521108_7 nucleic-acid-binding protein, contains PIN domain - - - 0.000000000000000000000000006683 117.0
PYH2_k127_2521108_8 SpoVT / AbrB like domain - - - 0.00000000000001464 76.0
PYH2_k127_2521108_9 Putative transposase - - - 0.000000000001728 80.0
PYH2_k127_2539338_0 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 305.0
PYH2_k127_2539338_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000007521 246.0
PYH2_k127_2539338_2 ornithine cyclodeaminase K01750 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000004572 231.0
PYH2_k127_2553906_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1483.0
PYH2_k127_2553906_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1281.0
PYH2_k127_2553906_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 507.0
PYH2_k127_2553906_11 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 504.0
PYH2_k127_2553906_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 487.0
PYH2_k127_2553906_13 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 426.0
PYH2_k127_2553906_14 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
PYH2_k127_2553906_15 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
PYH2_k127_2553906_16 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 352.0
PYH2_k127_2553906_17 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 326.0
PYH2_k127_2553906_18 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 332.0
PYH2_k127_2553906_19 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
PYH2_k127_2553906_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.035e-277 864.0
PYH2_k127_2553906_20 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 299.0
PYH2_k127_2553906_21 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
PYH2_k127_2553906_22 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003502 280.0
PYH2_k127_2553906_23 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 254.0
PYH2_k127_2553906_24 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
PYH2_k127_2553906_25 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
PYH2_k127_2553906_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000005887 195.0
PYH2_k127_2553906_27 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000082 155.0
PYH2_k127_2553906_28 YGGT family K02221 - - 0.0000000000000000000000000000000000000000491 158.0
PYH2_k127_2553906_29 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000004352 138.0
PYH2_k127_2553906_3 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.493e-249 780.0
PYH2_k127_2553906_30 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001142 83.0
PYH2_k127_2553906_31 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000001309 72.0
PYH2_k127_2553906_32 - K06950 - - 0.000000002453 63.0
PYH2_k127_2553906_34 Protein of unknown function (DUF721) - - - 0.0005437 49.0
PYH2_k127_2553906_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.151e-211 661.0
PYH2_k127_2553906_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 8.211e-202 637.0
PYH2_k127_2553906_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 560.0
PYH2_k127_2553906_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 551.0
PYH2_k127_2553906_8 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 543.0
PYH2_k127_2553906_9 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 537.0
PYH2_k127_2621222_0 Tripartite tricarboxylate transporter TctA family - - - 9.078e-253 788.0
PYH2_k127_2621222_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 592.0
PYH2_k127_2621222_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 482.0
PYH2_k127_2621222_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 470.0
PYH2_k127_2621222_4 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000001285 161.0
PYH2_k127_268921_0 CoA binding domain K09181 - - 8.236e-199 634.0
PYH2_k127_268921_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 580.0
PYH2_k127_2693818_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 3.034e-312 969.0
PYH2_k127_2693818_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 464.0
PYH2_k127_2693818_2 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
PYH2_k127_2693818_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 445.0
PYH2_k127_2693818_4 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
PYH2_k127_2693818_5 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 357.0
PYH2_k127_2693818_6 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 304.0
PYH2_k127_2693818_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001573 280.0
PYH2_k127_2693818_8 Cytochrome K08738 - - 0.0000000000000000000000000000000001356 134.0
PYH2_k127_2693818_9 - - - - 0.000000000007597 67.0
PYH2_k127_2719328_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000002315 240.0
PYH2_k127_2719328_1 Domain of unknown function (DUF4437) - - - 0.00000001381 57.0
PYH2_k127_2738309_0 cysteine protease - - - 5.167e-233 738.0
PYH2_k127_2738309_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000009476 73.0
PYH2_k127_2806561_0 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 300.0
PYH2_k127_2806561_1 Putative metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
PYH2_k127_2806561_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0008326 44.0
PYH2_k127_2814123_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1566.0
PYH2_k127_2814123_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.35e-322 993.0
PYH2_k127_2814123_10 Succinate dehydrogenase, hydrophobic K00242 - - 0.000000000000000000000000000000007534 136.0
PYH2_k127_2814123_11 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000006057 104.0
PYH2_k127_2814123_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.098e-316 981.0
PYH2_k127_2814123_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.225e-314 977.0
PYH2_k127_2814123_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.185e-249 776.0
PYH2_k127_2814123_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 567.0
PYH2_k127_2814123_6 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 446.0
PYH2_k127_2814123_7 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000002276 199.0
PYH2_k127_2814123_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000444 151.0
PYH2_k127_2814123_9 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000003545 134.0
PYH2_k127_2817623_0 FAD linked oxidase domain protein - - - 0.0 2001.0
PYH2_k127_2817623_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.581e-266 834.0
PYH2_k127_2817623_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
PYH2_k127_2817623_11 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
PYH2_k127_2817623_12 Lysine exporter protein (Lyse ygga) K11250 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 291.0
PYH2_k127_2817623_13 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
PYH2_k127_2817623_14 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000259 285.0
PYH2_k127_2817623_15 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000008012 269.0
PYH2_k127_2817623_16 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
PYH2_k127_2817623_17 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
PYH2_k127_2817623_18 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 252.0
PYH2_k127_2817623_19 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
PYH2_k127_2817623_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.011e-214 676.0
PYH2_k127_2817623_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000001216 251.0
PYH2_k127_2817623_21 HIT domain - - - 0.000000000000000000000000000000000000000000000007316 176.0
PYH2_k127_2817623_22 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000002361 179.0
PYH2_k127_2817623_23 Ferredoxin - - - 0.0000000000000000000000000000000000000000000009851 167.0
PYH2_k127_2817623_24 SMART Transport-associated and nodulation region - - - 0.00000000000000000000000000000000000000000087 164.0
PYH2_k127_2817623_25 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000001503 164.0
PYH2_k127_2817623_26 - - - - 0.000000000000000000000000000000000000005116 157.0
PYH2_k127_2817623_27 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000817 156.0
PYH2_k127_2817623_28 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000005803 151.0
PYH2_k127_2817623_29 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000012 121.0
PYH2_k127_2817623_3 Cell shape determining protein, MreB Mrl family K03569 - - 6.885e-199 624.0
PYH2_k127_2817623_30 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000001474 119.0
PYH2_k127_2817623_31 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001659 123.0
PYH2_k127_2817623_32 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000006066 116.0
PYH2_k127_2817623_33 PFAM Sporulation domain protein - - - 0.00000000001709 74.0
PYH2_k127_2817623_34 - - - - 0.0000000004963 67.0
PYH2_k127_2817623_4 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 602.0
PYH2_k127_2817623_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 541.0
PYH2_k127_2817623_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 514.0
PYH2_k127_2817623_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 465.0
PYH2_k127_2817623_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
PYH2_k127_2817623_9 PFAM Serine threonine protein kinase-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 377.0
PYH2_k127_2829743_0 Belongs to the ABC transporter superfamily K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 434.0
PYH2_k127_2829743_1 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
PYH2_k127_2829743_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 385.0
PYH2_k127_2829743_3 COG1176 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 381.0
PYH2_k127_2829743_4 ABC transporter permease K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 359.0
PYH2_k127_2829743_5 transcriptional - - - 0.0000000000000000000000000000000000000000001548 170.0
PYH2_k127_2829743_6 Acyl-transferase - - - 0.0000000000000000000000003264 107.0
PYH2_k127_2832579_0 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 591.0
PYH2_k127_2832579_1 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 316.0
PYH2_k127_2832579_10 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000004155 54.0
PYH2_k127_2832579_11 Protein of unknown function (DUF3617) - - - 0.0001163 51.0
PYH2_k127_2832579_13 Tripartite tricarboxylate transporter family receptor - - - 0.000215 44.0
PYH2_k127_2832579_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
PYH2_k127_2832579_3 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
PYH2_k127_2832579_4 Protein of unknown function (DUF1778) - - - 0.00000000000000000000000000000000000002485 145.0
PYH2_k127_2832579_5 Plasmid stabilization system K19092 - - 0.00000000000000000000000000000000000004428 145.0
PYH2_k127_2832579_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000003833 153.0
PYH2_k127_2832579_7 Dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000002932 134.0
PYH2_k127_2832579_8 GYD domain - - - 0.00000000000000000000000000001804 120.0
PYH2_k127_2832579_9 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000002389 105.0
PYH2_k127_2833469_0 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000000000000000000000000000004601 221.0
PYH2_k127_2833469_1 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000007145 159.0
PYH2_k127_2833469_2 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000001466 141.0
PYH2_k127_2833469_3 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.00000000000000000000005942 103.0
PYH2_k127_2833469_4 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000002195 65.0
PYH2_k127_2834114_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.597e-218 688.0
PYH2_k127_2834114_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.143e-199 627.0
PYH2_k127_2834114_10 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
PYH2_k127_2834114_11 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006693 237.0
PYH2_k127_2834114_12 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000003735 214.0
PYH2_k127_2834114_13 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000005194 210.0
PYH2_k127_2834114_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000002313 160.0
PYH2_k127_2834114_15 Modulates RecA activity K03565 - - 0.000000000000000000000000000000003124 134.0
PYH2_k127_2834114_16 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000002561 135.0
PYH2_k127_2834114_17 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000006663 118.0
PYH2_k127_2834114_18 - - - - 0.00000000000001405 77.0
PYH2_k127_2834114_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 581.0
PYH2_k127_2834114_3 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 544.0
PYH2_k127_2834114_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 509.0
PYH2_k127_2834114_5 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 444.0
PYH2_k127_2834114_6 Mg2 and Co2 transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
PYH2_k127_2834114_7 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 352.0
PYH2_k127_2834114_8 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 345.0
PYH2_k127_2834114_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 310.0
PYH2_k127_2838471_0 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
PYH2_k127_2838471_1 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000009161 199.0
PYH2_k127_2838471_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000005005 182.0
PYH2_k127_2838471_3 EamA-like transporter family - - - 0.00000000000000000002405 91.0
PYH2_k127_2841229_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.39e-279 875.0
PYH2_k127_2841229_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000007257 83.0
PYH2_k127_2843333_0 Domain of unknown function (DUF3362) - - - 1.924e-319 984.0
PYH2_k127_2843333_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 467.0
PYH2_k127_2843333_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
PYH2_k127_2843333_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.0000000000000000000000000000000000000000000000000000000000000000000026 240.0
PYH2_k127_2843333_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000005745 231.0
PYH2_k127_2843333_13 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000000000007169 214.0
PYH2_k127_2843333_14 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000001621 218.0
PYH2_k127_2843333_15 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
PYH2_k127_2843333_16 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000002504 210.0
PYH2_k127_2843333_17 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000007369 198.0
PYH2_k127_2843333_18 TPM domain - - - 0.00000000000000000000000000000000000000000000000001395 185.0
PYH2_k127_2843333_19 - - - - 0.00000000000000000000000000000000000005788 146.0
PYH2_k127_2843333_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 402.0
PYH2_k127_2843333_20 SnoaL-like domain - - - 0.000000000000000000000000000000002639 133.0
PYH2_k127_2843333_21 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001383 102.0
PYH2_k127_2843333_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
PYH2_k127_2843333_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
PYH2_k127_2843333_5 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 330.0
PYH2_k127_2843333_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
PYH2_k127_2843333_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 289.0
PYH2_k127_2843333_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002112 288.0
PYH2_k127_2843333_9 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004041 290.0
PYH2_k127_284773_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 593.0
PYH2_k127_284773_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 539.0
PYH2_k127_284773_2 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 385.0
PYH2_k127_2857728_0 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 313.0
PYH2_k127_2857728_1 Putative transposase - - - 0.0000000000008622 74.0
PYH2_k127_2857728_2 Transposase IS116 IS110 IS902 family - - - 0.000000000005467 70.0
PYH2_k127_2857728_3 Putative transposase - - - 0.0000007834 58.0
PYH2_k127_2860441_0 Protein of unknown function (DUF1298) - - - 1.72e-237 746.0
PYH2_k127_2860441_1 Single cache domain 3 - - - 0.00000000000000000000000000000000000000000000000000000000002422 215.0
PYH2_k127_2860441_2 Protein of unknown function (DUF2846) - - - 0.000000000000000000005589 99.0
PYH2_k127_2860441_3 - - - - 0.0000682 47.0
PYH2_k127_2910101_0 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 1.425e-266 833.0
PYH2_k127_2910101_1 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000003864 227.0
PYH2_k127_2910101_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000001601 187.0
PYH2_k127_2917506_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 490.0
PYH2_k127_2917506_1 PIN domain - - - 0.0000000000000000000000000000000000000000000001834 170.0
PYH2_k127_2917506_2 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000004194 159.0
PYH2_k127_2917506_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000001972 126.0
PYH2_k127_2917506_4 Sulfatase - - - 0.00000000000000000000184 94.0
PYH2_k127_2919426_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1007.0
PYH2_k127_2919426_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.613e-214 674.0
PYH2_k127_2919426_2 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 520.0
PYH2_k127_2919426_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 412.0
PYH2_k127_2919426_4 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 365.0
PYH2_k127_2919426_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000005935 152.0
PYH2_k127_2919426_6 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000126 153.0
PYH2_k127_2919426_7 Tautomerase enzyme - - - 0.0000000000000000000000000000000000003113 146.0
PYH2_k127_2919426_8 PEP-CTERM motif - - - 0.000000003096 59.0
PYH2_k127_2919426_9 protein related to plant photosystem II stability assembly factor - - - 0.0000107 55.0
PYH2_k127_292916_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.083e-214 672.0
PYH2_k127_292916_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 312.0
PYH2_k127_2929597_0 Site-specific recombinase, DNA invertase Pin - - - 5.31e-272 853.0
PYH2_k127_2929597_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 285.0
PYH2_k127_2929597_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000002932 169.0
PYH2_k127_2929597_3 - - - - 0.00000000009075 69.0
PYH2_k127_2929597_4 PFAM IstB domain protein ATP-binding protein - - - 0.00000003625 54.0
PYH2_k127_2951171_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 470.0
PYH2_k127_2951171_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 461.0
PYH2_k127_2951171_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000001379 149.0
PYH2_k127_2951171_3 COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component - - - 0.0001341 45.0
PYH2_k127_2998599_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.562e-304 939.0
PYH2_k127_2998599_1 Histidine ammonia-lyase K01745 - 4.3.1.3 8.949e-200 634.0
PYH2_k127_2998599_10 Auxin binding protein - - - 0.00000000000000000000000000000000000000000008211 164.0
PYH2_k127_2998599_2 Histidine ammonia-lyase K01745 - 4.3.1.3 3.093e-196 629.0
PYH2_k127_2998599_3 ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 512.0
PYH2_k127_2998599_4 glycine betaine K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 460.0
PYH2_k127_2998599_5 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 377.0
PYH2_k127_2998599_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 330.0
PYH2_k127_2998599_7 ABC-type proline glycine betaine transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
PYH2_k127_2998599_8 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008246 264.0
PYH2_k127_2998599_9 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000004517 222.0
PYH2_k127_3005469_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1317.0
PYH2_k127_3005469_1 PFAM extracellular solute-binding protein family 1 K05813 - - 1.925e-230 730.0
PYH2_k127_3005469_10 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 327.0
PYH2_k127_3005469_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
PYH2_k127_3005469_12 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
PYH2_k127_3005469_13 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000044 275.0
PYH2_k127_3005469_14 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000004273 253.0
PYH2_k127_3005469_15 Tat pathway signal - - - 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
PYH2_k127_3005469_16 Tat pathway signal - - - 0.00000000000000000000000000000000000000000005133 177.0
PYH2_k127_3005469_17 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000004701 163.0
PYH2_k127_3005469_19 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000004691 104.0
PYH2_k127_3005469_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 598.0
PYH2_k127_3005469_20 Protein of unknown function (DUF1501) - - - 0.00000000001457 71.0
PYH2_k127_3005469_21 Protein of unknown function (DUF1800) - - - 0.00000294 51.0
PYH2_k127_3005469_3 Pilus retraction K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 582.0
PYH2_k127_3005469_4 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 581.0
PYH2_k127_3005469_5 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 609.0
PYH2_k127_3005469_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 469.0
PYH2_k127_3005469_7 THUMP domain K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 435.0
PYH2_k127_3005469_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 355.0
PYH2_k127_3005469_9 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
PYH2_k127_3013931_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.725e-206 657.0
PYH2_k127_3013931_1 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 532.0
PYH2_k127_3013931_2 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 419.0
PYH2_k127_3013931_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 404.0
PYH2_k127_3013931_4 Rubrerythrin - - - 0.000000000000000001527 90.0
PYH2_k127_3020310_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.13e-226 720.0
PYH2_k127_3020310_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 511.0
PYH2_k127_3020310_10 Pfam Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 311.0
PYH2_k127_3020310_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 304.0
PYH2_k127_3020310_12 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
PYH2_k127_3020310_13 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 306.0
PYH2_k127_3020310_14 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
PYH2_k127_3020310_15 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000008087 220.0
PYH2_k127_3020310_16 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
PYH2_k127_3020310_17 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000000000000000000000000000000002392 192.0
PYH2_k127_3020310_18 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000007785 178.0
PYH2_k127_3020310_19 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000006333 158.0
PYH2_k127_3020310_2 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 507.0
PYH2_k127_3020310_20 cell division protein - - - 0.000000000000000000000000000006914 127.0
PYH2_k127_3020310_21 exo-alpha-(2->6)-sialidase activity K01179,K01186,K12373,K17624 - 3.2.1.18,3.2.1.4,3.2.1.52,3.2.1.97 0.00000000003577 64.0
PYH2_k127_3020310_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 489.0
PYH2_k127_3020310_4 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 388.0
PYH2_k127_3020310_5 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
PYH2_k127_3020310_6 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
PYH2_k127_3020310_7 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 336.0
PYH2_k127_3020310_8 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 323.0
PYH2_k127_3020310_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 322.0
PYH2_k127_3028262_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1014.0
PYH2_k127_3028262_1 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.5e-323 1004.0
PYH2_k127_3028262_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 587.0
PYH2_k127_3028262_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 545.0
PYH2_k127_3028262_12 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 484.0
PYH2_k127_3028262_13 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 473.0
PYH2_k127_3028262_14 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 392.0
PYH2_k127_3028262_15 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
PYH2_k127_3028262_16 transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 348.0
PYH2_k127_3028262_17 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 340.0
PYH2_k127_3028262_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
PYH2_k127_3028262_19 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
PYH2_k127_3028262_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 9.703e-314 972.0
PYH2_k127_3028262_20 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
PYH2_k127_3028262_21 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003393 236.0
PYH2_k127_3028262_22 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000002105 220.0
PYH2_k127_3028262_23 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000003134 206.0
PYH2_k127_3028262_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000001094 160.0
PYH2_k127_3028262_25 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000001642 152.0
PYH2_k127_3028262_26 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000005539 146.0
PYH2_k127_3028262_27 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000002093 127.0
PYH2_k127_3028262_28 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000005583 122.0
PYH2_k127_3028262_29 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000001004 118.0
PYH2_k127_3028262_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 9.132e-300 928.0
PYH2_k127_3028262_30 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000004275 108.0
PYH2_k127_3028262_31 Psort location Cytoplasmic, score 8.96 - - - 0.0000000005694 61.0
PYH2_k127_3028262_32 Protein of unknown function (DUF3024) - - - 0.000000294 55.0
PYH2_k127_3028262_4 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.399e-279 869.0
PYH2_k127_3028262_5 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 1.67e-246 780.0
PYH2_k127_3028262_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.387e-241 749.0
PYH2_k127_3028262_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.833e-238 744.0
PYH2_k127_3028262_8 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 1.898e-207 657.0
PYH2_k127_3028262_9 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 5.32e-204 649.0
PYH2_k127_3051823_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.561e-235 744.0
PYH2_k127_3051823_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 578.0
PYH2_k127_3051823_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 540.0
PYH2_k127_3051823_3 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 526.0
PYH2_k127_3051823_4 Nicotinamidase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 299.0
PYH2_k127_3051823_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000001052 202.0
PYH2_k127_3051823_6 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000008489 169.0
PYH2_k127_3077339_0 Multicopper oxidase - - - 6.999e-246 777.0
PYH2_k127_3077339_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 3.937e-236 738.0
PYH2_k127_3077339_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000005142 222.0
PYH2_k127_3077339_11 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000007372 212.0
PYH2_k127_3077339_12 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000002874 178.0
PYH2_k127_3077339_13 - - - - 0.000000000000000000000000000000000000000003975 164.0
PYH2_k127_3077339_14 - - - - 0.000000000000000000000000001772 119.0
PYH2_k127_3077339_15 - - - - 0.00000000000000000000000742 106.0
PYH2_k127_3077339_16 Domain of unknown function (DUF1840) - - - 0.00000000000000041 82.0
PYH2_k127_3077339_17 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000006068 75.0
PYH2_k127_3077339_2 Prolyl oligopeptidase family - - - 1.758e-229 730.0
PYH2_k127_3077339_3 Sulfatase - - - 1.983e-218 691.0
PYH2_k127_3077339_4 von Willebrand factor, type A K07114 - - 2.822e-205 658.0
PYH2_k127_3077339_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 600.0
PYH2_k127_3077339_6 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 465.0
PYH2_k127_3077339_7 Two component transcriptional regulator K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 288.0
PYH2_k127_3077339_8 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
PYH2_k127_3077339_9 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008161 248.0
PYH2_k127_3082863_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 4.614e-219 702.0
PYH2_k127_3082863_1 protein containing a von Willebrand factor type A (vWA) domain - - - 8.537e-215 677.0
PYH2_k127_3082863_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 342.0
PYH2_k127_3082863_11 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
PYH2_k127_3082863_12 reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002552 273.0
PYH2_k127_3082863_13 Electron transfer DM13 - - - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
PYH2_k127_3082863_14 Nitroreductase family - - - 0.000000000000000000000000000000000000000000003303 171.0
PYH2_k127_3082863_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001043 167.0
PYH2_k127_3082863_16 Universal stress protein - - - 0.000000000000000000000000000000000001658 143.0
PYH2_k127_3082863_17 - - - - 0.000000000000000000001276 97.0
PYH2_k127_3082863_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 572.0
PYH2_k127_3082863_3 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 571.0
PYH2_k127_3082863_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 473.0
PYH2_k127_3082863_5 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 446.0
PYH2_k127_3082863_6 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 393.0
PYH2_k127_3082863_7 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
PYH2_k127_3082863_8 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 345.0
PYH2_k127_3082863_9 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
PYH2_k127_3092985_0 Evidence 2b Function of strongly homologous gene - - - 6.607e-227 712.0
PYH2_k127_3092985_1 - - - - 0.000000000000000000000000000000003864 134.0
PYH2_k127_3099437_0 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.08e-260 810.0
PYH2_k127_3099437_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 552.0
PYH2_k127_3099437_10 - - - - 0.00000000000000000000000000000000000003909 149.0
PYH2_k127_3099437_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000036 118.0
PYH2_k127_3099437_12 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000002384 100.0
PYH2_k127_3099437_2 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 490.0
PYH2_k127_3099437_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 425.0
PYH2_k127_3099437_4 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 401.0
PYH2_k127_3099437_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
PYH2_k127_3099437_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 337.0
PYH2_k127_3099437_7 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 313.0
PYH2_k127_3099437_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 294.0
PYH2_k127_3099437_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
PYH2_k127_3100450_0 helicase superfamily c-terminal domain K03724 - - 0.0 1071.0
PYH2_k127_3100450_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.1e-322 992.0
PYH2_k127_3100450_10 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 419.0
PYH2_k127_3100450_11 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 382.0
PYH2_k127_3100450_12 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
PYH2_k127_3100450_13 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
PYH2_k127_3100450_14 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000009334 188.0
PYH2_k127_3100450_15 aminopeptidase N - - - 0.0000000000000000000000000000000000004697 158.0
PYH2_k127_3100450_16 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000005185 141.0
PYH2_k127_3100450_17 SWIB/MDM2 domain K03169 - 5.99.1.2 0.0000000000000000000000000000000001134 138.0
PYH2_k127_3100450_18 Regulatory protein, FmdB family - - - 0.00000000000000000000000000002969 122.0
PYH2_k127_3100450_19 - - - - 0.0000000000000000000000000002965 116.0
PYH2_k127_3100450_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.247e-236 747.0
PYH2_k127_3100450_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000006939 101.0
PYH2_k127_3100450_21 Acetyltransferase (GNAT) domain - - - 0.000000000000000004994 91.0
PYH2_k127_3100450_22 PFAM CBS domain containing protein - - - 0.000000000000001681 90.0
PYH2_k127_3100450_3 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 2.96e-231 728.0
PYH2_k127_3100450_4 B12 binding domain - - - 1.016e-204 652.0
PYH2_k127_3100450_5 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 550.0
PYH2_k127_3100450_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 499.0
PYH2_k127_3100450_7 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 445.0
PYH2_k127_3100450_8 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 447.0
PYH2_k127_3100450_9 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 437.0
PYH2_k127_3111386_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 360.0
PYH2_k127_3111386_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 354.0
PYH2_k127_3111386_2 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
PYH2_k127_3111386_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
PYH2_k127_3111386_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000001793 201.0
PYH2_k127_3111386_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000002764 194.0
PYH2_k127_3133242_0 Hydrogenase maturation protease K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000008417 208.0
PYH2_k127_3133242_1 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001535 173.0
PYH2_k127_3133242_2 Helix-turn-helix K21498 - - 0.0000000000000000000001001 108.0
PYH2_k127_3133242_3 HupF/HypC family K04653 - - 0.0005061 44.0
PYH2_k127_3170439_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 4.759e-258 820.0
PYH2_k127_3170439_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 554.0
PYH2_k127_3170439_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 526.0
PYH2_k127_3170439_3 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 432.0
PYH2_k127_3170439_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 392.0
PYH2_k127_3170439_5 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
PYH2_k127_3170439_6 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000002495 105.0
PYH2_k127_3170439_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000002089 102.0
PYH2_k127_3170439_8 membrane - - - 0.000000001312 64.0
PYH2_k127_3171040_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 8.374e-264 834.0
PYH2_k127_3171040_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 2.581e-231 727.0
PYH2_k127_3171040_10 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001382 205.0
PYH2_k127_3171040_11 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000006287 188.0
PYH2_k127_3171040_12 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000001616 179.0
PYH2_k127_3171040_13 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000001234 185.0
PYH2_k127_3171040_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000005639 148.0
PYH2_k127_3171040_15 ASCH - - - 0.000000000000000000000000000000000001234 145.0
PYH2_k127_3171040_16 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000523 142.0
PYH2_k127_3171040_17 Galactose binding lectin domain - - - 0.00000005661 60.0
PYH2_k127_3171040_18 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.000001454 55.0
PYH2_k127_3171040_19 DnaJ domain protein - - - 0.0004557 49.0
PYH2_k127_3171040_2 dehydrogenase K00253 - 1.3.8.4 1.015e-222 694.0
PYH2_k127_3171040_3 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 8.807e-222 706.0
PYH2_k127_3171040_4 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 500.0
PYH2_k127_3171040_5 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 443.0
PYH2_k127_3171040_6 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 411.0
PYH2_k127_3171040_7 Cys/Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 417.0
PYH2_k127_3171040_8 threonine dehydratase K17989 GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 364.0
PYH2_k127_3171040_9 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008977 289.0
PYH2_k127_3187838_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 5.912e-260 814.0
PYH2_k127_3187838_1 Periplasmic binding protein K01999 - - 5.347e-203 648.0
PYH2_k127_3187838_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 430.0
PYH2_k127_3187838_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 428.0
PYH2_k127_3187838_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 394.0
PYH2_k127_3187838_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 345.0
PYH2_k127_3187838_6 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 293.0
PYH2_k127_3187838_7 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
PYH2_k127_3187838_8 Regulatory protein GntR HTH - - - 0.000000000000000000000000000004316 123.0
PYH2_k127_3189026_0 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 419.0
PYH2_k127_3189026_1 Protein of unknown function (DUF465) - - - 0.000000000000000000004757 95.0
PYH2_k127_3193543_0 Sarcosine oxidase, subunit beta K00303 - 1.5.3.1 2.963e-200 630.0
PYH2_k127_3193543_1 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003059 268.0
PYH2_k127_3193543_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000007268 146.0
PYH2_k127_3193543_3 Sarcosine oxidase, delta subunit family K22085 - 1.5.99.5 0.000000000000000000000000001465 117.0
PYH2_k127_3199703_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2361.0
PYH2_k127_3199703_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2296.0
PYH2_k127_3199703_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000000000008021 151.0
PYH2_k127_3199703_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000002726 87.0
PYH2_k127_3199703_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002828 72.0
PYH2_k127_3199703_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1234.0
PYH2_k127_3199703_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 338.0
PYH2_k127_3199703_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 305.0
PYH2_k127_3199703_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007039 274.0
PYH2_k127_3199703_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005945 267.0
PYH2_k127_3199703_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003233 250.0
PYH2_k127_3199703_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 230.0
PYH2_k127_3199703_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000033 189.0
PYH2_k127_3203250_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1199.0
PYH2_k127_3203250_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1e-323 994.0
PYH2_k127_3203250_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000003954 100.0
PYH2_k127_3203250_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 6.095e-220 692.0
PYH2_k127_3203250_3 Belongs to the thiolase family - - - 7.449e-212 664.0
PYH2_k127_3203250_4 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 626.0
PYH2_k127_3203250_5 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 456.0
PYH2_k127_3203250_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 433.0
PYH2_k127_3203250_7 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 297.0
PYH2_k127_3203250_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000002217 224.0
PYH2_k127_3203250_9 carbohydrate transport K11688 - - 0.000000000000000000000000000000000000000000000000000000000000009581 228.0
PYH2_k127_3249758_0 DEAD-like helicases superfamily - - - 5.175e-264 819.0
PYH2_k127_3249758_1 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.00003046 49.0
PYH2_k127_3309808_0 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 357.0
PYH2_k127_3309808_1 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 301.0
PYH2_k127_3309808_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000002083 71.0
PYH2_k127_3337710_0 synthetase K01907 - 6.2.1.16 1.101e-285 892.0
PYH2_k127_3337710_1 PFAM MmgE PrpD family protein - - - 7.074e-231 722.0
PYH2_k127_3337710_10 Glycine-zipper domain - - - 0.00000000000000000000000000000000001811 143.0
PYH2_k127_3337710_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000004861 122.0
PYH2_k127_3337710_12 Cytochrome c K17223 - - 0.0000000000000000000000004644 111.0
PYH2_k127_3337710_13 - - - - 0.000000000000000000000769 100.0
PYH2_k127_3337710_2 ABC transporter C-terminal domain K15738 - - 3.691e-230 729.0
PYH2_k127_3337710_3 Ammonium Transporter Family K03320,K06580 - - 1.048e-219 686.0
PYH2_k127_3337710_4 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 503.0
PYH2_k127_3337710_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 430.0
PYH2_k127_3337710_6 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 431.0
PYH2_k127_3337710_7 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 373.0
PYH2_k127_3337710_8 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000001573 224.0
PYH2_k127_3337710_9 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002529 214.0
PYH2_k127_3351172_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 509.0
PYH2_k127_3351172_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 385.0
PYH2_k127_3351172_10 redox protein, regulator of disulfide bond formation - - - 0.0000000000003389 81.0
PYH2_k127_3351172_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002493 259.0
PYH2_k127_3351172_3 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000003304 218.0
PYH2_k127_3351172_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000321 188.0
PYH2_k127_3351172_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000009095 187.0
PYH2_k127_3351172_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000002629 174.0
PYH2_k127_3351172_7 - - - - 0.0000000000000000000000000000000000000000001496 168.0
PYH2_k127_3351172_8 TonB-dependent Receptor Plug Domain K16087 - - 0.00000000000000000000005407 104.0
PYH2_k127_3351172_9 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000004417 109.0
PYH2_k127_3429897_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.839e-315 971.0
PYH2_k127_3429897_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 7.766e-267 833.0
PYH2_k127_3429897_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 494.0
PYH2_k127_3429897_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 428.0
PYH2_k127_3429897_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 356.0
PYH2_k127_3429897_5 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 334.0
PYH2_k127_3429897_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000001437 135.0
PYH2_k127_3429897_7 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000003501 72.0
PYH2_k127_3429897_8 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000101 74.0
PYH2_k127_3429897_9 - - - - 0.000000000181 70.0
PYH2_k127_3479517_0 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 447.0
PYH2_k127_3479517_1 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 387.0
PYH2_k127_3479517_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH2_k127_352748_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.346e-213 668.0
PYH2_k127_352748_1 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 4.324e-207 651.0
PYH2_k127_352748_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 4.415e-204 640.0
PYH2_k127_352748_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 486.0
PYH2_k127_352748_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 452.0
PYH2_k127_352748_5 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 407.0
PYH2_k127_352748_6 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
PYH2_k127_352748_7 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005959 261.0
PYH2_k127_352748_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000002442 245.0
PYH2_k127_352748_9 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000003116 186.0
PYH2_k127_3736751_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1094.0
PYH2_k127_3736751_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 1.346e-293 910.0
PYH2_k127_3736751_2 Belongs to the peptidase S16 family - - - 3.813e-280 882.0
PYH2_k127_3736751_3 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 559.0
PYH2_k127_3736751_4 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 488.0
PYH2_k127_3736751_5 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 493.0
PYH2_k127_3736751_6 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 490.0
PYH2_k127_3736751_7 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 460.0
PYH2_k127_3736751_8 AMP binding - - - 0.00004229 53.0
PYH2_k127_3749468_0 iron ion homeostasis - - - 1.839e-293 917.0
PYH2_k127_3749468_1 His Kinase A (phosphoacceptor) domain - - - 3.875e-266 830.0
PYH2_k127_3749468_10 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 310.0
PYH2_k127_3749468_11 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 297.0
PYH2_k127_3749468_12 - - - - 0.0000000000000000000000000000000000000000001229 168.0
PYH2_k127_3749468_13 BON domain - - - 0.00000000000000000000006164 101.0
PYH2_k127_3749468_14 Protein of unknown function (DUF3309) - - - 0.0000000000000000002448 89.0
PYH2_k127_3749468_15 Domain of unknown function (DUF3943) - - - 0.000000000002266 74.0
PYH2_k127_3749468_2 cheY-homologous receiver domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 432.0
PYH2_k127_3749468_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 393.0
PYH2_k127_3749468_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 407.0
PYH2_k127_3749468_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 381.0
PYH2_k127_3749468_6 Beta/gamma crystallins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 374.0
PYH2_k127_3749468_7 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
PYH2_k127_3749468_8 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 357.0
PYH2_k127_3749468_9 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 343.0
PYH2_k127_3752787_0 histidine kinase A domain protein - - - 8.169e-312 969.0
PYH2_k127_3752787_1 Response regulator receiver domain - - - 0.0001792 48.0
PYH2_k127_3753460_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 600.0
PYH2_k127_3753460_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 570.0
PYH2_k127_3753460_10 PFAM pyridoxamine 5-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
PYH2_k127_3753460_11 Glyoxalase bleomycin resistance - - - 0.0000000000000000000000000000000000000000000000000009705 185.0
PYH2_k127_3753460_12 Protein of unknown function (DUF1059) - - - 0.0000000000000000000000006435 106.0
PYH2_k127_3753460_13 - - - - 0.0000001623 53.0
PYH2_k127_3753460_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 497.0
PYH2_k127_3753460_3 succinylglutamate desuccinylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 409.0
PYH2_k127_3753460_4 PFAM ABC transporter related K10017,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
PYH2_k127_3753460_5 Ligated ion channel L-glutamate- and glycine-binding site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
PYH2_k127_3753460_6 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH2_k127_3753460_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
PYH2_k127_3753460_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 295.0
PYH2_k127_3753460_9 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006932 271.0
PYH2_k127_3760121_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.694e-214 670.0
PYH2_k127_3760121_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
PYH2_k127_3785738_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 535.0
PYH2_k127_3785738_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 377.0
PYH2_k127_3785738_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000004724 170.0
PYH2_k127_3785738_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000001773 51.0
PYH2_k127_3789702_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1708.0
PYH2_k127_3789702_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 7.026e-289 903.0
PYH2_k127_3789702_10 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 471.0
PYH2_k127_3789702_11 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 453.0
PYH2_k127_3789702_12 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 460.0
PYH2_k127_3789702_13 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 432.0
PYH2_k127_3789702_14 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
PYH2_k127_3789702_15 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
PYH2_k127_3789702_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 356.0
PYH2_k127_3789702_17 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
PYH2_k127_3789702_18 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 334.0
PYH2_k127_3789702_19 hydrolase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 332.0
PYH2_k127_3789702_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.513e-252 784.0
PYH2_k127_3789702_20 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
PYH2_k127_3789702_21 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 298.0
PYH2_k127_3789702_22 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 296.0
PYH2_k127_3789702_23 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 267.0
PYH2_k127_3789702_24 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
PYH2_k127_3789702_25 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
PYH2_k127_3789702_26 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
PYH2_k127_3789702_27 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
PYH2_k127_3789702_28 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
PYH2_k127_3789702_29 FAD dependent oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000004746 238.0
PYH2_k127_3789702_3 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 6.554e-240 758.0
PYH2_k127_3789702_30 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000002832 237.0
PYH2_k127_3789702_31 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000008606 223.0
PYH2_k127_3789702_32 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000001988 227.0
PYH2_k127_3789702_33 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000002602 221.0
PYH2_k127_3789702_34 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000006374 189.0
PYH2_k127_3789702_35 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000007798 177.0
PYH2_k127_3789702_36 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000003358 179.0
PYH2_k127_3789702_37 Dioxygenase K00449 - 1.13.11.3 0.00000000000000000000000000000000000000005635 161.0
PYH2_k127_3789702_38 LysM domain K08086 - - 0.000000000000000000000000000002297 124.0
PYH2_k127_3789702_39 Entericidin EcnA/B family - - - 0.000000007859 57.0
PYH2_k127_3789702_4 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 1.057e-222 704.0
PYH2_k127_3789702_40 ATPases associated with a variety of cellular activities K01996 - - 0.000009895 55.0
PYH2_k127_3789702_5 o-acetylhomoserine K01740 - 2.5.1.49 5.692e-217 679.0
PYH2_k127_3789702_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 594.0
PYH2_k127_3789702_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 582.0
PYH2_k127_3789702_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 572.0
PYH2_k127_3789702_9 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 516.0
PYH2_k127_3792729_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 600.0
PYH2_k127_3792729_1 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000033 222.0
PYH2_k127_3792729_2 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.0000000000000000000000000009502 116.0
PYH2_k127_3792729_3 - - - - 0.00000000000000004343 87.0
PYH2_k127_3809534_0 Protein of unknown function (DUF3604) - - - 2.852e-249 777.0
PYH2_k127_3809534_1 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000003432 164.0
PYH2_k127_3809534_3 - - - - 0.00000000000000000000000000009021 124.0
PYH2_k127_3810034_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1059.0
PYH2_k127_3810034_1 Histidine kinase - - - 0.0000000000000000000000000000000000006632 141.0
PYH2_k127_3812410_0 Transport of potassium into the cell K03549 - - 2.998e-229 726.0
PYH2_k127_3812410_1 nucleoside-diphosphate sugar epimerase - - - 1.8e-199 632.0
PYH2_k127_3812410_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 502.0
PYH2_k127_3812410_3 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 436.0
PYH2_k127_3812410_4 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 261.0
PYH2_k127_3812410_5 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
PYH2_k127_3812410_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000000000000000000000003092 113.0
PYH2_k127_3812410_7 Thioredoxin domain - - - 0.0000000000000000006304 89.0
PYH2_k127_3813645_0 Glucose / Sorbosone dehydrogenase - - - 5.884e-245 758.0
PYH2_k127_3813645_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000002829 128.0
PYH2_k127_3813645_2 PFAM Cytochrome C K17230 - - 0.000000000000000000000000001919 115.0
PYH2_k127_3816526_0 Cytochrome b(N-terminal)/b6/petB - - - 3.936e-231 732.0
PYH2_k127_3816526_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 480.0
PYH2_k127_3816526_2 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 292.0
PYH2_k127_3816526_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000002995 180.0
PYH2_k127_3816526_4 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000007933 119.0
PYH2_k127_3816526_5 - - - - 0.000000000006631 68.0
PYH2_k127_3816526_6 protein involved in response to NO K07234 - - 0.0005102 43.0
PYH2_k127_3826539_0 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 560.0
PYH2_k127_3826539_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 481.0
PYH2_k127_3826539_2 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 400.0
PYH2_k127_3826539_3 PFAM carboxyl transferase K01615 - 4.1.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 374.0
PYH2_k127_3826539_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009959 237.0
PYH2_k127_3826539_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000002478 142.0
PYH2_k127_3826539_6 Biotin-requiring enzyme - - - 0.000000000000000000002547 94.0
PYH2_k127_3826539_7 cellulase activity - - - 0.0000005462 63.0
PYH2_k127_3826539_8 Bacterial Ig-like domain (group 3) - - - 0.00001525 58.0
PYH2_k127_3827916_0 amine dehydrogenase activity - - - 1.229e-297 943.0
PYH2_k127_3827916_1 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 441.0
PYH2_k127_3827916_10 Zinc finger, swim domain protein - - - 0.0000000008996 67.0
PYH2_k127_3827916_11 peptidyl-tyrosine sulfation - - - 0.000003251 53.0
PYH2_k127_3827916_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 342.0
PYH2_k127_3827916_3 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003802 250.0
PYH2_k127_3827916_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000001473 177.0
PYH2_k127_3827916_5 Protease prsW family - - - 0.000000000000000000000000000000000000001567 160.0
PYH2_k127_3827916_6 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000005024 114.0
PYH2_k127_3827916_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000008928 121.0
PYH2_k127_3827916_8 Helix-turn-helix domain - - - 0.000000000000000000000000004885 113.0
PYH2_k127_3828802_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 569.0
PYH2_k127_3828802_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 323.0
PYH2_k127_3828802_2 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
PYH2_k127_3828802_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000004524 218.0
PYH2_k127_3828802_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000003367 216.0
PYH2_k127_3828802_5 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000002162 204.0
PYH2_k127_3828802_6 - - - - 0.0000000000000000000000000000003211 126.0
PYH2_k127_3831521_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 293.0
PYH2_k127_3831521_1 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000006597 158.0
PYH2_k127_3848757_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.498e-253 799.0
PYH2_k127_3848757_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 584.0
PYH2_k127_3848757_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 567.0
PYH2_k127_3848757_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 422.0
PYH2_k127_3848757_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
PYH2_k127_3848757_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
PYH2_k127_3848757_6 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000008296 214.0
PYH2_k127_3848757_7 Preprotein translocase K03210 - - 0.00000000000000000000000000000001873 130.0
PYH2_k127_3854148_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1429.0
PYH2_k127_3854148_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 2.023e-301 951.0
PYH2_k127_3854148_10 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 478.0
PYH2_k127_3854148_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 469.0
PYH2_k127_3854148_12 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 469.0
PYH2_k127_3854148_13 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 446.0
PYH2_k127_3854148_14 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 396.0
PYH2_k127_3854148_15 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 384.0
PYH2_k127_3854148_16 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 385.0
PYH2_k127_3854148_17 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 361.0
PYH2_k127_3854148_18 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 307.0
PYH2_k127_3854148_19 Proteasome subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
PYH2_k127_3854148_2 Peptidase family M3 K01414 - 3.4.24.70 1.522e-281 889.0
PYH2_k127_3854148_20 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
PYH2_k127_3854148_21 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008235 263.0
PYH2_k127_3854148_22 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008576 254.0
PYH2_k127_3854148_23 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001527 246.0
PYH2_k127_3854148_24 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
PYH2_k127_3854148_25 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000105 200.0
PYH2_k127_3854148_26 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000003514 195.0
PYH2_k127_3854148_27 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000005765 186.0
PYH2_k127_3854148_28 Endoribonuclease L-PSP K10013 - - 0.0000000000000000000000000000000000000000000000004106 180.0
PYH2_k127_3854148_29 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000007219 141.0
PYH2_k127_3854148_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.476e-267 837.0
PYH2_k127_3854148_30 - - - - 0.0000000000000000000002022 102.0
PYH2_k127_3854148_31 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000001333 93.0
PYH2_k127_3854148_32 UPF0126 domain - - - 0.0000000489 56.0
PYH2_k127_3854148_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.037e-235 738.0
PYH2_k127_3854148_5 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 9.047e-234 731.0
PYH2_k127_3854148_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 7.61e-208 661.0
PYH2_k127_3854148_7 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 604.0
PYH2_k127_3854148_8 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 550.0
PYH2_k127_3854148_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 522.0
PYH2_k127_3876763_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.3e-203 651.0
PYH2_k127_3876763_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 509.0
PYH2_k127_3876763_2 COG3245 Cytochrome c5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000253 243.0
PYH2_k127_3876763_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000002691 206.0
PYH2_k127_3876763_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000003293 164.0
PYH2_k127_3876763_5 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.000000000000000000000000000008235 122.0
PYH2_k127_3876763_6 TonB family K03832 - - 0.000000000000000009938 90.0
PYH2_k127_3876763_7 general secretion pathway protein K08084,K08085 - - 0.00000005773 61.0
PYH2_k127_3885860_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 7.78e-269 849.0
PYH2_k127_3885860_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.116e-242 762.0
PYH2_k127_3885860_10 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 372.0
PYH2_k127_3885860_11 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 344.0
PYH2_k127_3885860_12 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 336.0
PYH2_k127_3885860_13 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
PYH2_k127_3885860_14 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000001776 215.0
PYH2_k127_3885860_15 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000001084 198.0
PYH2_k127_3885860_16 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000003744 189.0
PYH2_k127_3885860_17 system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000005919 153.0
PYH2_k127_3885860_18 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000008521 155.0
PYH2_k127_3885860_19 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000837 158.0
PYH2_k127_3885860_2 PA domain - - - 9.243e-236 750.0
PYH2_k127_3885860_20 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000001736 143.0
PYH2_k127_3885860_21 PFAM Tol-Pal system TolA K03646 - - 0.0000000000000000000000008176 120.0
PYH2_k127_3885860_22 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000001611 61.0
PYH2_k127_3885860_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 512.0
PYH2_k127_3885860_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 488.0
PYH2_k127_3885860_5 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 468.0
PYH2_k127_3885860_6 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 446.0
PYH2_k127_3885860_7 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 442.0
PYH2_k127_3885860_8 dioxygenase activity K00477 - 1.14.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 398.0
PYH2_k127_3885860_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 392.0
PYH2_k127_3902812_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 439.0
PYH2_k127_3902812_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 411.0
PYH2_k127_3902812_2 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 407.0
PYH2_k127_3902812_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001739 280.0
PYH2_k127_3902812_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
PYH2_k127_3909879_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1856.0
PYH2_k127_3909879_1 oxidoreductase K04090 - 1.2.7.8 0.0 1461.0
PYH2_k127_3909879_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.613e-210 677.0
PYH2_k127_3909879_11 Competence protein K02238 - - 5.745e-195 636.0
PYH2_k127_3909879_12 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 593.0
PYH2_k127_3909879_13 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 599.0
PYH2_k127_3909879_14 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 594.0
PYH2_k127_3909879_15 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 558.0
PYH2_k127_3909879_16 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 527.0
PYH2_k127_3909879_17 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 451.0
PYH2_k127_3909879_18 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 373.0
PYH2_k127_3909879_19 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
PYH2_k127_3909879_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1055.0
PYH2_k127_3909879_20 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 366.0
PYH2_k127_3909879_21 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 364.0
PYH2_k127_3909879_22 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
PYH2_k127_3909879_23 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 301.0
PYH2_k127_3909879_24 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
PYH2_k127_3909879_25 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 290.0
PYH2_k127_3909879_26 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003882 277.0
PYH2_k127_3909879_27 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 260.0
PYH2_k127_3909879_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000713 273.0
PYH2_k127_3909879_29 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009227 244.0
PYH2_k127_3909879_3 A predicted alpha-helical domain with a conserved ER motif. - - - 3.46e-296 931.0
PYH2_k127_3909879_30 transcriptional regulator, Rrf2 family K13643 - - 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
PYH2_k127_3909879_31 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
PYH2_k127_3909879_32 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000471 211.0
PYH2_k127_3909879_33 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000004367 191.0
PYH2_k127_3909879_34 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000003387 190.0
PYH2_k127_3909879_35 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000008286 176.0
PYH2_k127_3909879_36 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000001387 179.0
PYH2_k127_3909879_37 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000017 172.0
PYH2_k127_3909879_38 NUDIX domain - - - 0.00000000000000000000000000000000000000000001667 175.0
PYH2_k127_3909879_39 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000005297 158.0
PYH2_k127_3909879_4 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.074e-284 886.0
PYH2_k127_3909879_40 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000006393 139.0
PYH2_k127_3909879_41 nitrogen regulatory protein P-II - - - 0.000000000000000000000000000004874 135.0
PYH2_k127_3909879_42 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000001262 111.0
PYH2_k127_3909879_43 Diguanylate cyclase - - - 0.0000000000000000000003917 109.0
PYH2_k127_3909879_44 - - - - 0.000000000000000000001925 96.0
PYH2_k127_3909879_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.981e-257 812.0
PYH2_k127_3909879_6 Circularly permuted ATP-grasp type 2 - - - 2.602e-244 762.0
PYH2_k127_3909879_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.546e-233 732.0
PYH2_k127_3909879_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.612e-227 706.0
PYH2_k127_3909879_9 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.165e-214 681.0
PYH2_k127_3927734_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 584.0
PYH2_k127_3927734_1 rieske 2fe-2s K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 425.0
PYH2_k127_3927734_10 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000001231 177.0
PYH2_k127_3927734_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000004526 169.0
PYH2_k127_3927734_12 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000004454 151.0
PYH2_k127_3927734_13 Hemerythrin HHE cation binding domain - - - 0.00000000000000001125 89.0
PYH2_k127_3927734_14 Heavy-metal resistance - - - 0.00000000000000867 82.0
PYH2_k127_3927734_15 Histidine kinase - - - 0.0000000000168 69.0
PYH2_k127_3927734_16 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000004384 54.0
PYH2_k127_3927734_2 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 419.0
PYH2_k127_3927734_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 340.0
PYH2_k127_3927734_4 Two component transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
PYH2_k127_3927734_5 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 293.0
PYH2_k127_3927734_6 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
PYH2_k127_3927734_7 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000372 197.0
PYH2_k127_3927734_8 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000005524 196.0
PYH2_k127_3927734_9 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000002234 193.0
PYH2_k127_3933336_0 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 2.483e-201 634.0
PYH2_k127_3933336_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 299.0
PYH2_k127_3933336_2 membrane - - - 0.000000000000000000000000000000000000000000000000000232 189.0
PYH2_k127_3946503_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 527.0
PYH2_k127_3946503_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 532.0
PYH2_k127_3946503_2 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 356.0
PYH2_k127_3946503_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
PYH2_k127_3946503_4 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
PYH2_k127_3946503_5 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000004014 193.0
PYH2_k127_3946503_6 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000000781 191.0
PYH2_k127_3946503_7 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001961 166.0
PYH2_k127_3946503_8 transcriptional regulator - - - 0.0000000000000000000000000000000000005675 144.0
PYH2_k127_3965874_0 Acyl-CoA dehydrogenase, middle domain - - - 3.741e-196 616.0
PYH2_k127_3965874_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000009851 179.0
PYH2_k127_3965874_2 - - - - 0.000000000000000000000000000000000000002742 151.0
PYH2_k127_3983546_0 GMP synthase C terminal domain K01951 - 6.3.5.2 1.121e-283 876.0
PYH2_k127_3983546_1 HupE / UreJ protein - - - 0.000000000000000000000000000000001495 139.0
PYH2_k127_3983546_2 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000018 65.0
PYH2_k127_3989465_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.342e-281 876.0
PYH2_k127_3989465_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.083e-215 680.0
PYH2_k127_3989465_10 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 307.0
PYH2_k127_3989465_11 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
PYH2_k127_3989465_12 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000000000000006536 211.0
PYH2_k127_3989465_13 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000004557 161.0
PYH2_k127_3989465_14 DNA mediated transformation - - - 0.000000000000000000000000000000000001278 147.0
PYH2_k127_3989465_15 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000001524 131.0
PYH2_k127_3989465_16 FMN binding - - - 0.0000000000000000000000000000006389 128.0
PYH2_k127_3989465_17 Phosphopantetheine attachment site - - - 0.000000000000000005392 94.0
PYH2_k127_3989465_18 - - - - 0.000004923 53.0
PYH2_k127_3989465_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 539.0
PYH2_k127_3989465_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 503.0
PYH2_k127_3989465_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 503.0
PYH2_k127_3989465_5 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 482.0
PYH2_k127_3989465_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 473.0
PYH2_k127_3989465_7 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 457.0
PYH2_k127_3989465_8 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 427.0
PYH2_k127_3989465_9 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 334.0
PYH2_k127_3989938_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1279.0
PYH2_k127_3989938_1 DNA helicase K03657 - 3.6.4.12 7.803e-282 902.0
PYH2_k127_3989938_10 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 289.0
PYH2_k127_3989938_11 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005018 267.0
PYH2_k127_3989938_12 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000000000000002266 212.0
PYH2_k127_3989938_13 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000002385 158.0
PYH2_k127_3989938_14 Multicopper oxidase - - - 0.000000000000000000000000000000000000001928 166.0
PYH2_k127_3989938_15 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000002444 141.0
PYH2_k127_3989938_16 - - - - 0.00000000000000000000000000009869 125.0
PYH2_k127_3989938_17 Ion channel - - - 0.00000000000000000000001509 105.0
PYH2_k127_3989938_18 Peptidase family M1 domain - - - 0.000000000000000002347 91.0
PYH2_k127_3989938_19 Protein of unknown function (DUF1800) - - - 0.000000001371 63.0
PYH2_k127_3989938_2 Putative modulator of DNA gyrase - - - 6.232e-200 633.0
PYH2_k127_3989938_20 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0009522 42.0
PYH2_k127_3989938_3 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 532.0
PYH2_k127_3989938_4 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 471.0
PYH2_k127_3989938_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
PYH2_k127_3989938_6 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 341.0
PYH2_k127_3989938_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 333.0
PYH2_k127_3989938_8 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 334.0
PYH2_k127_3989938_9 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 328.0
PYH2_k127_3996865_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 581.0
PYH2_k127_3996865_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 523.0
PYH2_k127_3996865_10 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000004615 96.0
PYH2_k127_3996865_11 Dynamin family - - - 0.00000000000008966 73.0
PYH2_k127_3996865_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 418.0
PYH2_k127_3996865_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
PYH2_k127_3996865_4 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 312.0
PYH2_k127_3996865_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
PYH2_k127_3996865_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001628 269.0
PYH2_k127_3996865_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
PYH2_k127_3996865_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000001689 145.0
PYH2_k127_3996865_9 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000000003639 136.0
PYH2_k127_4005764_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 1.564e-310 987.0
PYH2_k127_4005764_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.719e-222 699.0
PYH2_k127_4005764_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
PYH2_k127_4005764_11 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000000006709 214.0
PYH2_k127_4005764_12 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000001134 191.0
PYH2_k127_4005764_13 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000002978 190.0
PYH2_k127_4005764_14 Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000002711 159.0
PYH2_k127_4005764_15 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.000000000000000000000000000000000002377 150.0
PYH2_k127_4005764_16 Multisubunit Na H antiporter, MnhG subunit K05564,K05571 - - 0.000000000000000000000000000008863 126.0
PYH2_k127_4005764_17 PFAM multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000000001262 105.0
PYH2_k127_4005764_18 - - - - 0.0000000000001419 78.0
PYH2_k127_4005764_19 Protein of unknown function (DUF2934) - - - 0.0000004411 55.0
PYH2_k127_4005764_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 462.0
PYH2_k127_4005764_3 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 467.0
PYH2_k127_4005764_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 379.0
PYH2_k127_4005764_5 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 376.0
PYH2_k127_4005764_6 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 359.0
PYH2_k127_4005764_7 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 314.0
PYH2_k127_4005764_8 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000003181 221.0
PYH2_k127_4005764_9 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000004408 230.0
PYH2_k127_4010288_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.208e-210 659.0
PYH2_k127_4010288_1 type II secretion system protein E K02454 - - 3.485e-207 657.0
PYH2_k127_4010288_10 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001676 201.0
PYH2_k127_4010288_11 Type II secretion system (T2SS), protein N K02463 - - 0.0000000000000000000000000000000441 135.0
PYH2_k127_4010288_12 general secretion pathway protein K02457 - - 0.00000000000000000000000253 108.0
PYH2_k127_4010288_13 General secretion pathway K02462 - - 0.0000000000000000009169 92.0
PYH2_k127_4010288_14 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000001364 93.0
PYH2_k127_4010288_15 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000003196 93.0
PYH2_k127_4010288_16 General secretion pathway protein L K02461 - - 0.00000000000000006133 94.0
PYH2_k127_4010288_17 Ribosomal protein L33 K02913 - - 0.0000000000001812 70.0
PYH2_k127_4010288_18 general secretion pathway protein K02452 - - 0.000000000002887 76.0
PYH2_k127_4010288_19 helix_turn_helix ASNC type K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000005184 71.0
PYH2_k127_4010288_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 2.665e-203 639.0
PYH2_k127_4010288_3 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 617.0
PYH2_k127_4010288_4 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 512.0
PYH2_k127_4010288_5 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 430.0
PYH2_k127_4010288_6 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
PYH2_k127_4010288_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 299.0
PYH2_k127_4010288_8 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001797 238.0
PYH2_k127_4010288_9 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
PYH2_k127_404067_0 extracellular solute-binding protein, family 5 K02035 - - 5.947e-307 945.0
PYH2_k127_404067_1 Isocitrate lyase K01637 - 4.1.3.1 1.52e-250 777.0
PYH2_k127_404067_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
PYH2_k127_404067_11 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 387.0
PYH2_k127_404067_12 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 374.0
PYH2_k127_404067_13 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 323.0
PYH2_k127_404067_14 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 314.0
PYH2_k127_404067_15 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002666 288.0
PYH2_k127_404067_16 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006578 267.0
PYH2_k127_404067_17 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001927 263.0
PYH2_k127_404067_18 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
PYH2_k127_404067_19 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000105 104.0
PYH2_k127_404067_2 PFAM Mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 572.0
PYH2_k127_404067_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 556.0
PYH2_k127_404067_4 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 554.0
PYH2_k127_404067_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 527.0
PYH2_k127_404067_6 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
PYH2_k127_404067_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 522.0
PYH2_k127_404067_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 445.0
PYH2_k127_404067_9 LysR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 428.0
PYH2_k127_4051543_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000324 231.0
PYH2_k127_4051543_1 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000001959 180.0
PYH2_k127_4051543_2 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000004056 168.0
PYH2_k127_4051543_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000573 178.0
PYH2_k127_4051543_4 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000001297 131.0
PYH2_k127_4051543_5 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000002794 109.0
PYH2_k127_4051543_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000118 59.0
PYH2_k127_4056468_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 469.0
PYH2_k127_4056468_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000004669 152.0
PYH2_k127_4061649_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 526.0
PYH2_k127_408502_0 Penicillin amidase K01434 - 3.5.1.11 1.156e-235 755.0
PYH2_k127_409652_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 2.773e-276 861.0
PYH2_k127_409652_1 phenylacetic acid degradation protein paaN - - - 7.967e-259 809.0
PYH2_k127_409652_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 465.0
PYH2_k127_409652_11 reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 450.0
PYH2_k127_409652_12 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 418.0
PYH2_k127_409652_13 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 412.0
PYH2_k127_409652_14 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 395.0
PYH2_k127_409652_15 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 380.0
PYH2_k127_409652_16 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
PYH2_k127_409652_17 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 369.0
PYH2_k127_409652_18 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 366.0
PYH2_k127_409652_19 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 367.0
PYH2_k127_409652_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 3.631e-214 673.0
PYH2_k127_409652_20 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
PYH2_k127_409652_21 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 285.0
PYH2_k127_409652_22 O-Methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001182 271.0
PYH2_k127_409652_23 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001779 265.0
PYH2_k127_409652_24 lipopolysaccharide heptosyltransferase I K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002819 267.0
PYH2_k127_409652_25 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
PYH2_k127_409652_26 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000000000000000000000000000000008539 226.0
PYH2_k127_409652_27 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
PYH2_k127_409652_28 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.00000000000000000000000000000000000000000000000000002925 190.0
PYH2_k127_409652_29 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000000000000004114 178.0
PYH2_k127_409652_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.172e-212 668.0
PYH2_k127_409652_30 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000001051 148.0
PYH2_k127_409652_31 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000003997 115.0
PYH2_k127_409652_32 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000001815 100.0
PYH2_k127_409652_33 - - - - 0.000000000000000001242 88.0
PYH2_k127_409652_34 reverse transcriptase - - - 0.00000000000003796 75.0
PYH2_k127_409652_35 Transposase DDE domain group 1 - - - 0.0000000008907 63.0
PYH2_k127_409652_36 Histidine kinase - - - 0.00000006845 61.0
PYH2_k127_409652_37 reverse transcriptase - - - 0.000003686 51.0
PYH2_k127_409652_38 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00003284 48.0
PYH2_k127_409652_4 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 584.0
PYH2_k127_409652_5 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 595.0
PYH2_k127_409652_6 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 585.0
PYH2_k127_409652_7 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 574.0
PYH2_k127_409652_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 568.0
PYH2_k127_409652_9 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 502.0
PYH2_k127_4109312_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1134.0
PYH2_k127_4109312_1 Acyl-CoA dehydrogenase N terminal - - - 1.962e-271 850.0
PYH2_k127_4109312_10 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 323.0
PYH2_k127_4109312_11 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 308.0
PYH2_k127_4109312_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 279.0
PYH2_k127_4109312_13 PFAM Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000819 271.0
PYH2_k127_4109312_14 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
PYH2_k127_4109312_15 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
PYH2_k127_4109312_16 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
PYH2_k127_4109312_17 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000003223 211.0
PYH2_k127_4109312_18 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000687 207.0
PYH2_k127_4109312_19 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000002787 202.0
PYH2_k127_4109312_2 Acyl-CoA synthetase (NDP forming) K09181 - - 1.399e-259 829.0
PYH2_k127_4109312_20 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000001067 174.0
PYH2_k127_4109312_21 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000001063 169.0
PYH2_k127_4109312_22 TraB family K09973 - - 0.00000000000000000000000000000000000000000003565 172.0
PYH2_k127_4109312_23 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000001055 160.0
PYH2_k127_4109312_24 hydrogenase maturation protease - - - 0.00000000000000000000000000000000001974 140.0
PYH2_k127_4109312_26 assembly chaperone K07346 - - 0.000000000000000000000001191 114.0
PYH2_k127_4109312_27 dksA traR - - - 0.0000000000000000001135 94.0
PYH2_k127_4109312_28 Spore Coat Protein U domain - - - 0.0000000000000000001931 94.0
PYH2_k127_4109312_29 Secreted protein - - - 0.000000000000000006671 90.0
PYH2_k127_4109312_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 2.241e-249 779.0
PYH2_k127_4109312_30 Spore Coat Protein U domain - - - 0.00000000000001117 81.0
PYH2_k127_4109312_4 Belongs to the thiolase family K00632 - 2.3.1.16 7.108e-202 634.0
PYH2_k127_4109312_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 444.0
PYH2_k127_4109312_6 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 407.0
PYH2_k127_4109312_7 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 337.0
PYH2_k127_4109312_8 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 364.0
PYH2_k127_4109312_9 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 333.0
PYH2_k127_4128433_0 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 344.0
PYH2_k127_4128433_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 300.0
PYH2_k127_4128433_2 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000817 184.0
PYH2_k127_4128433_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10009 - - 0.0000000007552 59.0
PYH2_k127_4152098_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1212.0
PYH2_k127_4152098_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1124.0
PYH2_k127_4152098_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 437.0
PYH2_k127_4152098_11 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 442.0
PYH2_k127_4152098_12 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 421.0
PYH2_k127_4152098_13 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 409.0
PYH2_k127_4152098_14 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 422.0
PYH2_k127_4152098_15 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 398.0
PYH2_k127_4152098_16 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 403.0
PYH2_k127_4152098_17 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 395.0
PYH2_k127_4152098_18 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 387.0
PYH2_k127_4152098_19 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 368.0
PYH2_k127_4152098_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 5e-324 1015.0
PYH2_k127_4152098_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 345.0
PYH2_k127_4152098_21 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 336.0
PYH2_k127_4152098_22 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 318.0
PYH2_k127_4152098_23 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 283.0
PYH2_k127_4152098_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005947 273.0
PYH2_k127_4152098_25 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000136 232.0
PYH2_k127_4152098_26 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000009085 233.0
PYH2_k127_4152098_27 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
PYH2_k127_4152098_28 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000002201 209.0
PYH2_k127_4152098_29 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000003568 196.0
PYH2_k127_4152098_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.731e-288 899.0
PYH2_k127_4152098_30 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000007189 184.0
PYH2_k127_4152098_31 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000001121 178.0
PYH2_k127_4152098_32 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000001066 161.0
PYH2_k127_4152098_33 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000002723 162.0
PYH2_k127_4152098_34 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000008012 153.0
PYH2_k127_4152098_35 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000872 132.0
PYH2_k127_4152098_36 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000002147 131.0
PYH2_k127_4152098_37 Domain of unknown function (DUF4124) - - - 0.00000000000000003639 90.0
PYH2_k127_4152098_38 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000001194 75.0
PYH2_k127_4152098_39 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000009685 55.0
PYH2_k127_4152098_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.486e-286 899.0
PYH2_k127_4152098_5 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
PYH2_k127_4152098_6 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 500.0
PYH2_k127_4152098_7 C-terminal region of band_7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
PYH2_k127_4152098_8 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 466.0
PYH2_k127_4152098_9 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 449.0
PYH2_k127_4176673_0 Histidine kinase-like ATPases - - - 3.121e-316 1067.0
PYH2_k127_4176673_1 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 6.594e-275 863.0
PYH2_k127_4176673_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 9.335e-246 772.0
PYH2_k127_4176673_3 viral genome integration into host DNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 428.0
PYH2_k127_4176673_4 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 395.0
PYH2_k127_4176673_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 340.0
PYH2_k127_4176673_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
PYH2_k127_4176673_7 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000001784 188.0
PYH2_k127_4176673_8 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000003945 140.0
PYH2_k127_4176673_9 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000009349 136.0
PYH2_k127_4187292_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 1.809e-205 646.0
PYH2_k127_4187292_1 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 434.0
PYH2_k127_4201855_0 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 567.0
PYH2_k127_4201855_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 529.0
PYH2_k127_4201855_2 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 480.0
PYH2_k127_4201855_3 Belongs to the 'phage' integrase family - - - 0.000000000005988 67.0
PYH2_k127_4218569_0 GntP family permease - - - 1.706e-205 665.0
PYH2_k127_4218569_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 495.0
PYH2_k127_4218569_2 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000000000000000000000000000000005007 185.0
PYH2_k127_4218569_3 - - - - 0.000000000000002692 77.0
PYH2_k127_4235213_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2516.0
PYH2_k127_4235213_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.2e-256 796.0
PYH2_k127_4235213_2 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
PYH2_k127_4235213_3 Cupin 2, conserved barrel domain protein K11312 - - 0.00000000000000000000000000000000000000000000008447 174.0
PYH2_k127_4356753_0 Glycolate oxidase subunit GlcD K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.631e-230 730.0
PYH2_k127_4356753_1 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 8.884e-224 702.0
PYH2_k127_4356753_2 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 604.0
PYH2_k127_4356753_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 521.0
PYH2_k127_4356753_4 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 522.0
PYH2_k127_4356753_5 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 448.0
PYH2_k127_4356753_6 FAD binding K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 442.0
PYH2_k127_4356753_7 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001869 274.0
PYH2_k127_4356753_8 COG1226 Kef-type K transport systems - - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
PYH2_k127_4356753_9 Dodecin K09165 - - 0.0000000000000000001575 92.0
PYH2_k127_4427505_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 512.0
PYH2_k127_4427505_1 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 502.0
PYH2_k127_4427505_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 425.0
PYH2_k127_4427505_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 385.0
PYH2_k127_4427505_4 Serine hydroxymethyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 379.0
PYH2_k127_4427505_5 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
PYH2_k127_4427505_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009173 257.0
PYH2_k127_4427505_7 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000005728 235.0
PYH2_k127_4427505_8 PFAM BLUF domain protein - - - 0.000000000000000000000000000000000000000000000000000000003957 210.0
PYH2_k127_443101_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1707.0
PYH2_k127_443101_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1004.0
PYH2_k127_443101_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 480.0
PYH2_k127_443101_11 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 459.0
PYH2_k127_443101_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 372.0
PYH2_k127_443101_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 317.0
PYH2_k127_443101_14 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 287.0
PYH2_k127_443101_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006153 288.0
PYH2_k127_443101_16 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001668 266.0
PYH2_k127_443101_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 232.0
PYH2_k127_443101_18 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001104 222.0
PYH2_k127_443101_19 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000005136 206.0
PYH2_k127_443101_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 6.942e-199 635.0
PYH2_k127_443101_20 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000002661 205.0
PYH2_k127_443101_21 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000008644 202.0
PYH2_k127_443101_22 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000003904 183.0
PYH2_k127_443101_23 MAPEG family - - - 0.00000000000000000000000000000000002661 139.0
PYH2_k127_443101_24 CRS1_YhbY K07574 - - 0.00000000000000000000000000000001751 130.0
PYH2_k127_443101_25 competence protein - - - 0.0000000000000000000000000000001519 139.0
PYH2_k127_443101_26 PFAM EAL domain - - - 0.0000000000000000000000000001041 132.0
PYH2_k127_443101_27 PFAM porin Gram-negative type - - - 0.00000000000000000000000005641 113.0
PYH2_k127_443101_3 CoA-transferase family III K07749 - 2.8.3.16 2.956e-198 632.0
PYH2_k127_443101_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 7.046e-196 620.0
PYH2_k127_443101_5 binding-protein-dependent transport systems inner membrane component K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 603.0
PYH2_k127_443101_6 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 577.0
PYH2_k127_443101_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 579.0
PYH2_k127_443101_8 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 505.0
PYH2_k127_443101_9 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 503.0
PYH2_k127_4460959_0 oxidoreductase activity - - - 1.135e-298 925.0
PYH2_k127_4460959_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 599.0
PYH2_k127_4460959_2 DsrE/DsrF-like family K09004 - - 0.00000000006531 63.0
PYH2_k127_4673593_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 470.0
PYH2_k127_4673593_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 443.0
PYH2_k127_4673593_10 Plasmid stabilization system K19092 - - 0.00000000000000000000000000165 115.0
PYH2_k127_4673593_11 Phosphopantetheine attachment site - - - 0.00000000000000000003431 102.0
PYH2_k127_4673593_12 NADH pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.000000008318 59.0
PYH2_k127_4673593_13 nadh pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 0.00000002713 57.0
PYH2_k127_4673593_14 Cytochrome c - - - 0.00000006263 54.0
PYH2_k127_4673593_15 Cytochrome c - - - 0.0000005936 57.0
PYH2_k127_4673593_16 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000001378 53.0
PYH2_k127_4673593_17 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000748 52.0
PYH2_k127_4673593_2 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 421.0
PYH2_k127_4673593_3 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 392.0
PYH2_k127_4673593_4 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 396.0
PYH2_k127_4673593_5 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 366.0
PYH2_k127_4673593_6 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 344.0
PYH2_k127_4673593_7 YaeQ family - - - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
PYH2_k127_4673593_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000005948 196.0
PYH2_k127_4673593_9 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000001856 183.0
PYH2_k127_4677071_0 ABC-type dipeptide transport system periplasmic component K02035 - - 5.357e-218 691.0
PYH2_k127_4677071_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 590.0
PYH2_k127_4677071_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 503.0
PYH2_k127_4677071_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 492.0
PYH2_k127_4677071_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 421.0
PYH2_k127_4677071_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 416.0
PYH2_k127_4677071_6 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 412.0
PYH2_k127_4677071_7 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
PYH2_k127_4677071_8 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000002165 254.0
PYH2_k127_4677071_9 Belongs to the ParB family K03497 - - 0.0000000000000135 79.0
PYH2_k127_4684622_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.647e-200 638.0
PYH2_k127_4684622_1 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000000000000000000000000000000000000004557 228.0
PYH2_k127_4684622_2 - - - - 0.0000000000000000000000000000000000185 147.0
PYH2_k127_4684622_3 - - - - 0.0000000000000000000000000000000004175 143.0
PYH2_k127_4684622_4 s cog2930 - - - 0.000000000000001004 77.0
PYH2_k127_4687573_0 4Fe-4S dicluster domain - - - 1.761e-272 848.0
PYH2_k127_4709589_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.792e-242 750.0
PYH2_k127_4709589_1 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 5.108e-225 702.0
PYH2_k127_4709589_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 515.0
PYH2_k127_472287_0 Maltose transport system permease protein MalF P2 domain K10109 - - 2.197e-241 758.0
PYH2_k127_472287_1 Bacterial extracellular solute-binding protein K10108 - - 1.327e-220 689.0
PYH2_k127_472287_2 Binding-protein-dependent transport system inner membrane component K10110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 527.0
PYH2_k127_472287_3 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 286.0
PYH2_k127_472287_4 ABC transporter K10111 - - 0.0000000000000000000000000000000000000000000000000003061 187.0
PYH2_k127_4723745_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.32e-251 783.0
PYH2_k127_4723745_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.104e-227 708.0
PYH2_k127_4723745_10 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000004764 218.0
PYH2_k127_4723745_11 Sporulation related domain K03749 - - 0.0000000000000000000000124 110.0
PYH2_k127_4723745_12 Colicin V production protein K03558 - - 0.000000000000000000002029 102.0
PYH2_k127_4723745_13 Helix-hairpin-helix motif - - - 0.000000000000000000005388 96.0
PYH2_k127_4723745_14 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.000000000000000001065 90.0
PYH2_k127_4723745_15 - - - - 0.0000000000000008731 88.0
PYH2_k127_4723745_17 Domain of unknown function (DUF932) - - - 0.000134 44.0
PYH2_k127_4723745_2 Retron-type reverse transcriptase K00986 - 2.7.7.49 5.259e-204 651.0
PYH2_k127_4723745_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 571.0
PYH2_k127_4723745_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 512.0
PYH2_k127_4723745_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 488.0
PYH2_k127_4723745_6 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 375.0
PYH2_k127_4723745_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
PYH2_k127_4723745_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
PYH2_k127_4723745_9 LysM domain K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 320.0
PYH2_k127_4756976_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 4.141e-211 672.0
PYH2_k127_4756976_1 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 452.0
PYH2_k127_4756976_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000004252 252.0
PYH2_k127_4759116_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.53e-221 694.0
PYH2_k127_4759116_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
PYH2_k127_4776425_0 Proton-conducting membrane transporter - - - 8.531e-294 911.0
PYH2_k127_4776425_1 Proton-conducting membrane transporter K12141 - - 8.064e-245 779.0
PYH2_k127_4776425_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 2.225e-208 659.0
PYH2_k127_4776425_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 476.0
PYH2_k127_4776425_4 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 316.0
PYH2_k127_4776425_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
PYH2_k127_4798700_0 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 481.0
PYH2_k127_4798700_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 457.0
PYH2_k127_4798700_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 391.0
PYH2_k127_4798700_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 373.0
PYH2_k127_4798700_4 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 350.0
PYH2_k127_4822771_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 6.859e-303 933.0
PYH2_k127_4822771_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 539.0
PYH2_k127_4822771_2 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 372.0
PYH2_k127_4822771_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
PYH2_k127_4822771_4 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000001006 218.0
PYH2_k127_4822771_5 PFAM thiamineS protein - - - 0.000000000000000000000002801 104.0
PYH2_k127_4822771_6 - - - - 0.000000000003674 70.0
PYH2_k127_4822771_7 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000006944 63.0
PYH2_k127_4823421_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 416.0
PYH2_k127_4823421_1 molybdopterin cofactor binding - - - 0.000000008401 60.0
PYH2_k127_4842638_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1287.0
PYH2_k127_4842638_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 2.317e-277 879.0
PYH2_k127_4842638_10 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 317.0
PYH2_k127_4842638_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
PYH2_k127_4842638_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004664 269.0
PYH2_k127_4842638_13 HlyD family secretion protein K13408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
PYH2_k127_4842638_14 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001104 248.0
PYH2_k127_4842638_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001312 225.0
PYH2_k127_4842638_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000005491 227.0
PYH2_k127_4842638_17 enzyme binding - - - 0.000000000000000000000000000001065 127.0
PYH2_k127_4842638_2 FtsX-like permease family K02004 - - 1.508e-209 679.0
PYH2_k127_4842638_3 Peptidase C39 family K13409 - - 1.225e-205 664.0
PYH2_k127_4842638_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 544.0
PYH2_k127_4842638_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
PYH2_k127_4842638_6 Lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 458.0
PYH2_k127_4842638_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 418.0
PYH2_k127_4842638_8 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 380.0
PYH2_k127_4842638_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 331.0
PYH2_k127_4856047_0 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
PYH2_k127_4856047_1 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000002192 179.0
PYH2_k127_4856047_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000223 178.0
PYH2_k127_4856047_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000003056 119.0
PYH2_k127_4856047_4 Peptidase propeptide and YPEB domain - - - 0.00000000003364 69.0
PYH2_k127_4861480_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1030.0
PYH2_k127_4861480_1 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 491.0
PYH2_k127_4861480_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 301.0
PYH2_k127_4861480_3 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000002686 183.0
PYH2_k127_4861480_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000007439 174.0
PYH2_k127_4861480_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000001342 118.0
PYH2_k127_4861480_6 PFAM Copper binding periplasmic protein CusF - - - 0.000000000001224 72.0
PYH2_k127_4874289_0 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 0.0 1178.0
PYH2_k127_4874289_1 transport systems, ATPase components K02056 - 3.6.3.17 5.186e-260 809.0
PYH2_k127_4874289_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 514.0
PYH2_k127_4874289_3 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002093 283.0
PYH2_k127_4874289_4 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000007865 181.0
PYH2_k127_4878131_0 Efflux pump membrane transporter K18138 - - 0.0 1369.0
PYH2_k127_4878131_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 382.0
PYH2_k127_4895_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 591.0
PYH2_k127_4895_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
PYH2_k127_4895_2 Patatin phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 412.0
PYH2_k127_4895_3 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 396.0
PYH2_k127_4895_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000002103 199.0
PYH2_k127_4895_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000003609 112.0
PYH2_k127_4895_6 abc transporter K06020 - 3.6.3.25 0.000000000000000008964 86.0
PYH2_k127_4895_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000839 48.0
PYH2_k127_4903860_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 3.126e-241 767.0
PYH2_k127_4903860_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 539.0
PYH2_k127_4903860_10 - - - - 0.000000000000000002451 89.0
PYH2_k127_4903860_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 468.0
PYH2_k127_4903860_3 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 462.0
PYH2_k127_4903860_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381 278.0
PYH2_k127_4903860_5 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001009 239.0
PYH2_k127_4903860_6 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000008929 227.0
PYH2_k127_4903860_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000001365 197.0
PYH2_k127_4903860_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000388 157.0
PYH2_k127_4903860_9 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000007736 98.0
PYH2_k127_4942488_0 CoA binding domain - - - 2.656e-296 923.0
PYH2_k127_4942488_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 560.0
PYH2_k127_4942488_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 421.0
PYH2_k127_4942488_3 (GMC) oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004608 275.0
PYH2_k127_4942488_4 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
PYH2_k127_4942488_5 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000102 215.0
PYH2_k127_4942488_6 PFAM CHRD domain containing protein - - - 0.00000000000000001038 91.0
PYH2_k127_5004845_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 374.0
PYH2_k127_5004845_1 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 354.0
PYH2_k127_5004845_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
PYH2_k127_5004845_3 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000006282 186.0
PYH2_k127_5004845_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000004573 159.0
PYH2_k127_5004845_5 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000002274 97.0
PYH2_k127_501050_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 538.0
PYH2_k127_501050_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 413.0
PYH2_k127_501050_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 293.0
PYH2_k127_501050_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000001412 212.0
PYH2_k127_5024110_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 6.876e-274 856.0
PYH2_k127_5024110_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 4.732e-212 670.0
PYH2_k127_5024110_10 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000002912 222.0
PYH2_k127_5024110_11 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000469 133.0
PYH2_k127_5024110_12 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000002261 108.0
PYH2_k127_5024110_13 ferredoxin - - - 0.00000000000009751 73.0
PYH2_k127_5024110_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 594.0
PYH2_k127_5024110_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 563.0
PYH2_k127_5024110_4 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 383.0
PYH2_k127_5024110_5 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 368.0
PYH2_k127_5024110_6 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
PYH2_k127_5024110_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 341.0
PYH2_k127_5024110_8 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 320.0
PYH2_k127_5024110_9 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
PYH2_k127_50485_0 - - - - 0.0000000000000000000000000000000000000001729 158.0
PYH2_k127_50485_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000003554 91.0
PYH2_k127_50485_2 - - - - 0.000000000003408 72.0
PYH2_k127_5099561_0 AMP-binding enzyme C-terminal domain K02182,K20034 GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044464,GO:0071704 6.2.1.44,6.2.1.48 5.26e-275 852.0
PYH2_k127_510170_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 9.744e-273 861.0
PYH2_k127_510170_1 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 327.0
PYH2_k127_510170_2 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004029 261.0
PYH2_k127_510170_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
PYH2_k127_510170_4 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000001392 187.0
PYH2_k127_510170_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000005018 165.0
PYH2_k127_5137549_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.25e-321 991.0
PYH2_k127_5137549_1 PFAM amidohydrolase K01464 - 3.5.2.2 8.063e-268 830.0
PYH2_k127_5137549_10 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000000004454 168.0
PYH2_k127_5137549_11 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000003307 145.0
PYH2_k127_5137549_12 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000134 140.0
PYH2_k127_5137549_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 552.0
PYH2_k127_5137549_3 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 376.0
PYH2_k127_5137549_4 Trap dicarboxylate transporter, dctm subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 350.0
PYH2_k127_5137549_5 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
PYH2_k127_5137549_6 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
PYH2_k127_5137549_7 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000136 248.0
PYH2_k127_5137549_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000007749 195.0
PYH2_k127_5137549_9 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000001462 184.0
PYH2_k127_5137894_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 4.824e-314 972.0
PYH2_k127_5137894_1 heat shock protein binding - - - 1.487e-265 833.0
PYH2_k127_5137894_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 570.0
PYH2_k127_5137894_3 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 301.0
PYH2_k127_5137894_4 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003644 241.0
PYH2_k127_5137894_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001427 238.0
PYH2_k127_5137894_6 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001893 231.0
PYH2_k127_5137894_7 Psort location Cytoplasmic, score 9.97 K07666 - - 0.000000000000000000000000000000000000000000000000000000000002441 219.0
PYH2_k127_5137894_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000008941 210.0
PYH2_k127_5137894_9 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000007624 158.0
PYH2_k127_5184250_0 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 543.0
PYH2_k127_5184250_1 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 392.0
PYH2_k127_5184250_2 surface antigen variable number repeat protein K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
PYH2_k127_5184250_3 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 335.0
PYH2_k127_5184250_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000001205 190.0
PYH2_k127_5210212_0 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 582.0
PYH2_k127_5210212_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 382.0
PYH2_k127_5210212_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 352.0
PYH2_k127_5210212_4 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000006741 216.0
PYH2_k127_5210212_5 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000001504 147.0
PYH2_k127_5210212_6 - - - - 0.000000000000000000000000422 113.0
PYH2_k127_5210212_7 PFAM cytochrome P450 - - - 0.00000001108 62.0
PYH2_k127_521258_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 509.0
PYH2_k127_521258_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 488.0
PYH2_k127_521258_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001299 266.0
PYH2_k127_521258_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000008434 182.0
PYH2_k127_521258_4 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000001702 180.0
PYH2_k127_521258_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00001506 47.0
PYH2_k127_5264005_0 Binding-protein-dependent transport system inner membrane component K17323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 477.0
PYH2_k127_5264005_1 ABC transporter (Permease K17322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 321.0
PYH2_k127_5264005_2 small integral membrane protein - - - 0.0000000000000000000000000000000002435 134.0
PYH2_k127_5264005_3 EamA-like transporter family - - - 0.0000000000001812 70.0
PYH2_k127_5319366_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 369.0
PYH2_k127_5319366_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
PYH2_k127_5319366_2 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 296.0
PYH2_k127_5319366_3 Transcriptional regulatory protein, C terminal K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 286.0
PYH2_k127_5319366_4 Belongs to the 'phage' integrase family - - - 0.000000001481 60.0
PYH2_k127_5344278_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1041.0
PYH2_k127_5344278_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 2.418e-244 769.0
PYH2_k127_5344278_10 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
PYH2_k127_5344278_11 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 325.0
PYH2_k127_5344278_12 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 326.0
PYH2_k127_5344278_13 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 257.0
PYH2_k127_5344278_14 Prokaryotic cytochrome b561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
PYH2_k127_5344278_15 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
PYH2_k127_5344278_16 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
PYH2_k127_5344278_17 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000136 222.0
PYH2_k127_5344278_18 succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000397 197.0
PYH2_k127_5344278_19 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000000135 143.0
PYH2_k127_5344278_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 3.984e-224 705.0
PYH2_k127_5344278_20 - - - - 0.0000000000000000000000000000000000002705 141.0
PYH2_k127_5344278_21 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000223 150.0
PYH2_k127_5344278_22 GYD domain - - - 0.000000000000000000000000000000000006008 138.0
PYH2_k127_5344278_23 - - - - 0.0000000000000000000000000000001586 130.0
PYH2_k127_5344278_24 Protein of unknown function DUF86 - - - 0.000000000000000000000000000003371 123.0
PYH2_k127_5344278_25 Protein of unknown function (DUF504) - - - 0.00000000000000000000000003902 110.0
PYH2_k127_5344278_26 - - - - 0.00000000000000001165 83.0
PYH2_k127_5344278_27 Protein required for attachment to host cells - - - 0.0000000000000001752 85.0
PYH2_k127_5344278_29 Transcriptional regulator - - - 0.0001273 45.0
PYH2_k127_5344278_3 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 586.0
PYH2_k127_5344278_4 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 562.0
PYH2_k127_5344278_5 binding-protein-dependent transport systems inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 477.0
PYH2_k127_5344278_6 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 433.0
PYH2_k127_5344278_7 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 354.0
PYH2_k127_5344278_8 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 335.0
PYH2_k127_5344278_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 327.0
PYH2_k127_5346038_0 Aminotransferase class-III K00823 - 2.6.1.19 1.053e-215 677.0
PYH2_k127_5346038_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004356 241.0
PYH2_k127_5349433_0 mechanosensitive ion channel K03442,K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
PYH2_k127_5349433_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 316.0
PYH2_k127_5360805_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1665.0
PYH2_k127_5360805_1 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1069.0
PYH2_k127_5360805_10 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 397.0
PYH2_k127_5360805_11 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 394.0
PYH2_k127_5360805_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
PYH2_k127_5360805_13 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 343.0
PYH2_k127_5360805_14 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 295.0
PYH2_k127_5360805_15 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009648 265.0
PYH2_k127_5360805_16 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001494 258.0
PYH2_k127_5360805_17 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005642 261.0
PYH2_k127_5360805_18 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001483 233.0
PYH2_k127_5360805_19 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000001186 219.0
PYH2_k127_5360805_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.941e-221 706.0
PYH2_k127_5360805_20 - - - - 0.0000000000000000000000000000000000000000000000000000119 193.0
PYH2_k127_5360805_21 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000001108 162.0
PYH2_k127_5360805_22 DsrC like protein K11179 - - 0.000000000000000000000000000000000000007504 151.0
PYH2_k127_5360805_23 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000000002702 144.0
PYH2_k127_5360805_24 PFAM UspA domain protein K07090 - - 0.00000000000000000000000000000005384 138.0
PYH2_k127_5360805_25 - - - - 0.00000000000000000000000000002426 125.0
PYH2_k127_5360805_26 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000702 109.0
PYH2_k127_5360805_27 - - - - 0.00000000000000000000001452 109.0
PYH2_k127_5360805_28 - - - - 0.000000000000000000005034 104.0
PYH2_k127_5360805_29 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000002132 89.0
PYH2_k127_5360805_3 PUA-like domain K00958 - 2.7.7.4 1.01e-215 674.0
PYH2_k127_5360805_4 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 564.0
PYH2_k127_5360805_5 binding domain K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 520.0
PYH2_k127_5360805_6 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 486.0
PYH2_k127_5360805_7 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
PYH2_k127_5360805_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 411.0
PYH2_k127_5360805_9 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 406.0
PYH2_k127_5379147_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1557.0
PYH2_k127_5379147_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.738e-258 815.0
PYH2_k127_5379147_10 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 498.0
PYH2_k127_5379147_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 495.0
PYH2_k127_5379147_12 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 481.0
PYH2_k127_5379147_13 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 471.0
PYH2_k127_5379147_14 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 463.0
PYH2_k127_5379147_15 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 436.0
PYH2_k127_5379147_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
PYH2_k127_5379147_17 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 366.0
PYH2_k127_5379147_18 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
PYH2_k127_5379147_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
PYH2_k127_5379147_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.261e-229 715.0
PYH2_k127_5379147_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
PYH2_k127_5379147_21 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 291.0
PYH2_k127_5379147_22 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
PYH2_k127_5379147_23 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH2_k127_5379147_24 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000001126 258.0
PYH2_k127_5379147_25 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000002012 235.0
PYH2_k127_5379147_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
PYH2_k127_5379147_27 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004096 240.0
PYH2_k127_5379147_28 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000006204 183.0
PYH2_k127_5379147_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000007442 171.0
PYH2_k127_5379147_3 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 2.575e-210 657.0
PYH2_k127_5379147_30 Lecithin retinol acyltransferase - - - 0.0000000000000000000000000000000000000002279 158.0
PYH2_k127_5379147_31 glutamate synthase - - - 0.00000000000000000000000000000000002449 137.0
PYH2_k127_5379147_32 Ferredoxin K05337 - - 0.0000000000000000000000000000000004418 133.0
PYH2_k127_5379147_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000003703 122.0
PYH2_k127_5379147_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000023 115.0
PYH2_k127_5379147_35 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000007732 102.0
PYH2_k127_5379147_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.931e-208 655.0
PYH2_k127_5379147_5 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 8.557e-197 626.0
PYH2_k127_5379147_6 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 590.0
PYH2_k127_5379147_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 574.0
PYH2_k127_5379147_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 559.0
PYH2_k127_5379147_9 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
PYH2_k127_538109_0 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000001868 148.0
PYH2_k127_538109_1 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000143 110.0
PYH2_k127_538109_2 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000001111 95.0
PYH2_k127_538109_3 positive regulation of growth - - - 0.0000000000000000003705 88.0
PYH2_k127_538109_4 peptidase - - - 0.00000000000003796 75.0
PYH2_k127_538109_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000001775 61.0
PYH2_k127_5473235_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001989 282.0
PYH2_k127_5473235_1 Molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
PYH2_k127_5473235_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000002119 184.0
PYH2_k127_5484070_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3201.0
PYH2_k127_5484070_1 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 589.0
PYH2_k127_5484070_10 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000004057 237.0
PYH2_k127_5484070_11 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH2_k127_5484070_12 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000000372 197.0
PYH2_k127_5484070_13 Regulator K01420 - - 0.000000000000000000000000000000000000000000005755 177.0
PYH2_k127_5484070_14 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000477 171.0
PYH2_k127_5484070_16 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000001712 141.0
PYH2_k127_5484070_17 - - - - 0.000000000000000000000000000001788 125.0
PYH2_k127_5484070_18 - - - - 0.000000000000000000000002281 108.0
PYH2_k127_5484070_19 7TM receptor with intracellular HD hydrolase - - - 0.000000000000000000000171 101.0
PYH2_k127_5484070_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 471.0
PYH2_k127_5484070_20 - - - - 0.000000000000000006761 92.0
PYH2_k127_5484070_21 Rubrerythrin - - - 0.000000000000000008964 86.0
PYH2_k127_5484070_22 - - - - 0.000000000000009145 76.0
PYH2_k127_5484070_23 Belongs to the UPF0337 (CsbD) family - - - 0.0000002285 57.0
PYH2_k127_5484070_24 PFAM AMP-dependent synthetase and ligase - - - 0.0005623 44.0
PYH2_k127_5484070_3 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 429.0
PYH2_k127_5484070_4 ABC-type sugar transport system, permease component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 426.0
PYH2_k127_5484070_5 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 406.0
PYH2_k127_5484070_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 370.0
PYH2_k127_5484070_7 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
PYH2_k127_5484070_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
PYH2_k127_5484070_9 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009121 241.0
PYH2_k127_5519424_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 581.0
PYH2_k127_5519424_1 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000879 278.0
PYH2_k127_5519424_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000006958 192.0
PYH2_k127_5637760_0 Belongs to the malic enzymes family K00029 - 1.1.1.40 6.558e-320 996.0
PYH2_k127_5637760_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 2.236e-248 775.0
PYH2_k127_5637760_10 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 426.0
PYH2_k127_5637760_11 aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 409.0
PYH2_k127_5637760_12 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 412.0
PYH2_k127_5637760_13 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 367.0
PYH2_k127_5637760_14 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
PYH2_k127_5637760_15 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
PYH2_k127_5637760_16 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
PYH2_k127_5637760_17 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000578 250.0
PYH2_k127_5637760_18 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
PYH2_k127_5637760_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
PYH2_k127_5637760_2 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 2.524e-246 768.0
PYH2_k127_5637760_20 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003702 229.0
PYH2_k127_5637760_21 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000007083 187.0
PYH2_k127_5637760_22 Formate dehydrogenase gamma subunit K00127 - - 0.000000000000000000000000000000000000000000000004934 182.0
PYH2_k127_5637760_23 OmpA family - - - 0.000000000000000000000000000000000000001781 157.0
PYH2_k127_5637760_24 MaoC like domain - - - 0.000000000000000000000000000000000000004269 151.0
PYH2_k127_5637760_25 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000001313 137.0
PYH2_k127_5637760_26 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000003659 138.0
PYH2_k127_5637760_27 PFAM FecR protein - - - 0.000000000000000000000001483 108.0
PYH2_k127_5637760_28 - - - - 0.000000000000000000001242 98.0
PYH2_k127_5637760_29 - - - - 0.000000000000000007315 93.0
PYH2_k127_5637760_3 Highly conserved protein containing a thioredoxin domain K06888 - - 6.115e-243 769.0
PYH2_k127_5637760_30 STAS domain K06378 - - 0.000000000000002268 81.0
PYH2_k127_5637760_31 Putative transposase - - - 0.000000000002084 67.0
PYH2_k127_5637760_32 Histidine kinase-like ATPase domain - - - 0.00000000001417 72.0
PYH2_k127_5637760_33 - - - - 0.00003086 53.0
PYH2_k127_5637760_4 Phosphoesterase family - - - 2.067e-197 627.0
PYH2_k127_5637760_5 Pyridoxamine 5'-phosphate K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 571.0
PYH2_k127_5637760_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 510.0
PYH2_k127_5637760_7 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
PYH2_k127_5637760_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 481.0
PYH2_k127_5637760_9 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 440.0
PYH2_k127_5646379_0 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 305.0
PYH2_k127_5646379_1 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002443 248.0
PYH2_k127_5646379_2 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000000000000000000000093 239.0
PYH2_k127_5646379_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000009685 50.0
PYH2_k127_5648522_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 8.415e-205 646.0
PYH2_k127_5648522_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 510.0
PYH2_k127_5648522_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000812 259.0
PYH2_k127_5648522_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000008031 243.0
PYH2_k127_5648522_4 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000003772 209.0
PYH2_k127_5648522_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000009164 147.0
PYH2_k127_5648522_6 Amidohydrolase family - - - 0.00007329 54.0
PYH2_k127_5652250_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 1.426e-214 674.0
PYH2_k127_5652250_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 571.0
PYH2_k127_5652250_2 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000266 289.0
PYH2_k127_5652250_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001327 223.0
PYH2_k127_5652250_4 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000000000000001925 143.0
PYH2_k127_5652250_5 Redoxin - - - 0.000000000000000000000000009349 110.0
PYH2_k127_5652250_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000002851 108.0
PYH2_k127_5652250_7 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000005178 119.0
PYH2_k127_5652250_8 - - - - 0.0002086 51.0
PYH2_k127_5657907_0 IS66 C-terminal element - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
PYH2_k127_5657907_1 COG3436 Transposase and inactivated derivatives K07484 - - 0.00000000000000000000000000000000000000000000002102 178.0
PYH2_k127_5657907_2 COG2801 Transposase and inactivated derivatives - - - 0.000000002929 63.0
PYH2_k127_566205_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 421.0
PYH2_k127_566205_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 342.0
PYH2_k127_566205_2 Protein of unknown function (DUF3429) - - - 0.000000000000000000002371 99.0
PYH2_k127_566205_3 Zinc-binding dehydrogenase - - - 0.00000000000002105 75.0
PYH2_k127_567730_0 DNA polymerase X family K02347 - - 3.348e-234 737.0
PYH2_k127_567730_1 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 452.0
PYH2_k127_567730_10 response regulator - - - 0.000000000000000000000000008568 124.0
PYH2_k127_567730_11 - - - - 0.00000000000000001153 88.0
PYH2_k127_567730_12 - - - - 0.000000000155 67.0
PYH2_k127_567730_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 447.0
PYH2_k127_567730_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 428.0
PYH2_k127_567730_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
PYH2_k127_567730_5 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 289.0
PYH2_k127_567730_6 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 241.0
PYH2_k127_567730_7 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
PYH2_k127_567730_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000003584 145.0
PYH2_k127_567730_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000004004 138.0
PYH2_k127_5678656_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1559.0
PYH2_k127_5678656_1 L-serine dehydratase K01752 - 4.3.1.17 1.855e-228 719.0
PYH2_k127_5678656_10 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 329.0
PYH2_k127_5678656_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
PYH2_k127_5678656_12 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH2_k127_5678656_13 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000545 213.0
PYH2_k127_5678656_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000002432 184.0
PYH2_k127_5678656_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 584.0
PYH2_k127_5678656_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 560.0
PYH2_k127_5678656_4 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 532.0
PYH2_k127_5678656_5 D-aminoacylase domain protein K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 518.0
PYH2_k127_5678656_6 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
PYH2_k127_5678656_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 458.0
PYH2_k127_5678656_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 438.0
PYH2_k127_5678656_9 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 426.0
PYH2_k127_5692863_0 Strictosidine synthase K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 539.0
PYH2_k127_5702285_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1091.0
PYH2_k127_5702285_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.82e-318 981.0
PYH2_k127_5702285_10 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.627e-213 679.0
PYH2_k127_5702285_11 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 561.0
PYH2_k127_5702285_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 499.0
PYH2_k127_5702285_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 488.0
PYH2_k127_5702285_14 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 471.0
PYH2_k127_5702285_15 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 457.0
PYH2_k127_5702285_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 387.0
PYH2_k127_5702285_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 325.0
PYH2_k127_5702285_19 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 318.0
PYH2_k127_5702285_2 NADH-quinone oxidoreductase K00336 - 1.6.5.3 6.41e-303 943.0
PYH2_k127_5702285_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 312.0
PYH2_k127_5702285_21 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
PYH2_k127_5702285_22 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 281.0
PYH2_k127_5702285_23 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009433 275.0
PYH2_k127_5702285_24 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
PYH2_k127_5702285_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001531 199.0
PYH2_k127_5702285_26 - - - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
PYH2_k127_5702285_27 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000225 177.0
PYH2_k127_5702285_28 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000003237 151.0
PYH2_k127_5702285_29 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000001503 143.0
PYH2_k127_5702285_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.253e-266 826.0
PYH2_k127_5702285_30 Twin-arginine translocation pathway signal protein - - - 0.0000000000000000000000000000000004461 138.0
PYH2_k127_5702285_31 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000001143 132.0
PYH2_k127_5702285_32 PFAM RDD domain containing protein - - - 0.0000000000000000000000000002122 121.0
PYH2_k127_5702285_33 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000001903 107.0
PYH2_k127_5702285_34 Protein of unknown function (DUF3106) - - - 0.000000000000000004375 91.0
PYH2_k127_5702285_35 Protein of unknown function (DUF3619) - - - 0.00000000003347 72.0
PYH2_k127_5702285_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.434e-256 792.0
PYH2_k127_5702285_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.691e-248 780.0
PYH2_k127_5702285_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 7.761e-247 766.0
PYH2_k127_5702285_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.168e-227 721.0
PYH2_k127_5702285_8 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.261e-223 706.0
PYH2_k127_5702285_9 GMC oxidoreductase - - - 6.774e-222 700.0
PYH2_k127_5705342_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001698 274.0
PYH2_k127_5705342_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001355 135.0
PYH2_k127_5705354_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 527.0
PYH2_k127_5705354_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
PYH2_k127_5705354_2 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000003901 217.0
PYH2_k127_5712319_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1105.0
PYH2_k127_5712319_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.353e-302 947.0
PYH2_k127_5712319_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000004445 240.0
PYH2_k127_5712319_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
PYH2_k127_5712319_12 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000241 209.0
PYH2_k127_5712319_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003707 194.0
PYH2_k127_5712319_14 Histidine kinase - - - 0.000000000000000000002037 108.0
PYH2_k127_5712319_15 Antirepressor K07741 - - 0.0009869 49.0
PYH2_k127_5712319_2 Extracellular solute-binding protein K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 597.0
PYH2_k127_5712319_3 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 483.0
PYH2_k127_5712319_4 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 451.0
PYH2_k127_5712319_5 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 417.0
PYH2_k127_5712319_6 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 366.0
PYH2_k127_5712319_7 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 368.0
PYH2_k127_5712319_8 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH2_k127_5712319_9 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004655 267.0
PYH2_k127_5725636_0 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
PYH2_k127_5725636_1 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.00000000000000000000000000000005569 128.0
PYH2_k127_5725636_2 transport system fused permease components - - - 0.000000000000000000001064 96.0
PYH2_k127_5725636_3 Domain of unknown function (DUF1850) - - - 0.000000000000000003878 89.0
PYH2_k127_5736769_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1409.0
PYH2_k127_5736769_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.096e-303 937.0
PYH2_k127_5736769_10 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 301.0
PYH2_k127_5736769_11 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 283.0
PYH2_k127_5736769_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
PYH2_k127_5736769_13 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
PYH2_k127_5736769_14 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000001094 260.0
PYH2_k127_5736769_15 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
PYH2_k127_5736769_16 AsmA family - - - 0.0000000000000000000000000000000000000000000000000000000000003999 234.0
PYH2_k127_5736769_17 - - - - 0.00000000000000000000000000000000000000000003499 176.0
PYH2_k127_5736769_18 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000003235 161.0
PYH2_k127_5736769_19 Histidine kinase K20974 - 2.7.13.3 0.0000000000000000000000006204 105.0
PYH2_k127_5736769_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 519.0
PYH2_k127_5736769_20 Histidine Phosphotransfer domain - - - 0.0000000000000000000001674 100.0
PYH2_k127_5736769_21 Helix-hairpin-helix motif K02237 - - 0.0000000000000000001716 96.0
PYH2_k127_5736769_22 Lipopolysaccharide assembly protein A domain K08992 - - 0.0001322 50.0
PYH2_k127_5736769_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 511.0
PYH2_k127_5736769_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 486.0
PYH2_k127_5736769_5 beta' subunit K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 484.0
PYH2_k127_5736769_6 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 475.0
PYH2_k127_5736769_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 473.0
PYH2_k127_5736769_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 374.0
PYH2_k127_5736769_9 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 342.0
PYH2_k127_5758941_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.359e-240 753.0
PYH2_k127_5758941_1 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 1.626e-222 702.0
PYH2_k127_5758941_10 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 397.0
PYH2_k127_5758941_11 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 387.0
PYH2_k127_5758941_12 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 365.0
PYH2_k127_5758941_13 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 367.0
PYH2_k127_5758941_14 Type ii and iii secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 297.0
PYH2_k127_5758941_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
PYH2_k127_5758941_16 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
PYH2_k127_5758941_17 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000003445 213.0
PYH2_k127_5758941_18 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000005562 176.0
PYH2_k127_5758941_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 583.0
PYH2_k127_5758941_20 - - - - 0.00000000000001169 80.0
PYH2_k127_5758941_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 523.0
PYH2_k127_5758941_4 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 522.0
PYH2_k127_5758941_5 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 495.0
PYH2_k127_5758941_6 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
PYH2_k127_5758941_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 452.0
PYH2_k127_5758941_8 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 426.0
PYH2_k127_5758941_9 Dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 406.0
PYH2_k127_5760689_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 584.0
PYH2_k127_5760689_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 441.0
PYH2_k127_5760689_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 411.0
PYH2_k127_5760689_3 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
PYH2_k127_5760689_4 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000009299 163.0
PYH2_k127_5760689_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000003757 149.0
PYH2_k127_5760689_6 Phospholipid methyltransferase - - - 0.0000000000000000002513 98.0
PYH2_k127_5760689_7 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000003326 62.0
PYH2_k127_5769799_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.815e-312 964.0
PYH2_k127_5769799_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 558.0
PYH2_k127_5769799_2 UTRA domain K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 345.0
PYH2_k127_5769799_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 326.0
PYH2_k127_5769799_4 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000001833 179.0
PYH2_k127_5769799_5 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000001999 188.0
PYH2_k127_5769799_6 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000000000000003313 175.0
PYH2_k127_5769799_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002049 83.0
PYH2_k127_5769831_0 PFAM extracellular solute-binding protein family 1 K05813 - - 3.159e-236 736.0
PYH2_k127_5769831_1 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 494.0
PYH2_k127_5769831_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
PYH2_k127_5769831_3 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 464.0
PYH2_k127_5769831_4 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000009437 57.0
PYH2_k127_5769831_5 signal transduction protein containing sensor and EAL - - - 0.0000002405 54.0
PYH2_k127_5769831_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0001317 49.0
PYH2_k127_5770807_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 475.0
PYH2_k127_5770807_1 NADH:flavin oxidoreductase / NADH oxidase family K00354,K09461 - 1.14.13.40,1.6.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 466.0
PYH2_k127_5770807_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
PYH2_k127_5770807_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000006765 202.0
PYH2_k127_5770807_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000002496 184.0
PYH2_k127_5770807_5 CAAX protease self-immunity K07052 - - 0.000000000000000000002407 104.0
PYH2_k127_5770807_6 Prokaryotic cytochrome b561 K12262 - - 0.0005693 43.0
PYH2_k127_5776118_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2250.0
PYH2_k127_5776118_1 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1279.0
PYH2_k127_5776118_2 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 1.042e-215 683.0
PYH2_k127_5776118_3 Magnesium transport protein CorA - - - 1.939e-204 659.0
PYH2_k127_5776118_4 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
PYH2_k127_5776118_5 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000004232 198.0
PYH2_k127_5795415_0 Aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 502.0
PYH2_k127_5795415_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 463.0
PYH2_k127_5795415_10 protein conserved in bacteria K09966 - - 0.000000000000000000000001933 107.0
PYH2_k127_5795415_11 PIN domain - - - 0.0000000000000000000008544 102.0
PYH2_k127_5795415_12 3' exoribonuclease, RNase T-like - - - 0.0000333 57.0
PYH2_k127_5795415_2 DNA recombination protein, rmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
PYH2_k127_5795415_3 Elements of external origin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 428.0
PYH2_k127_5795415_4 major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 338.0
PYH2_k127_5795415_5 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
PYH2_k127_5795415_6 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009597 254.0
PYH2_k127_5795415_7 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000008423 196.0
PYH2_k127_5795415_8 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000002082 167.0
PYH2_k127_5795415_9 - - - - 0.00000000000000000000000000000000000000000002655 167.0
PYH2_k127_5812417_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
PYH2_k127_5812417_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000008632 183.0
PYH2_k127_5823322_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 4.942e-264 820.0
PYH2_k127_5823322_1 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.605e-254 789.0
PYH2_k127_5823322_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
PYH2_k127_5823322_11 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000002434 228.0
PYH2_k127_5823322_12 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
PYH2_k127_5823322_13 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
PYH2_k127_5823322_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001559 189.0
PYH2_k127_5823322_15 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000001636 185.0
PYH2_k127_5823322_16 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000104 166.0
PYH2_k127_5823322_17 mRNA catabolic process - - - 0.0000000000000000000000000000000000000007348 156.0
PYH2_k127_5823322_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000006251 149.0
PYH2_k127_5823322_19 zinc-ribbon domain - - - 0.0000000000000000000000000000000000004756 154.0
PYH2_k127_5823322_2 RNB K01147 - 3.1.13.1 3.691e-220 700.0
PYH2_k127_5823322_20 KTSC domain - - - 0.000000000000000000000000000001052 121.0
PYH2_k127_5823322_21 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000001162 60.0
PYH2_k127_5823322_3 Malic enzyme K00029 - 1.1.1.40 4.168e-208 654.0
PYH2_k127_5823322_4 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.547e-202 639.0
PYH2_k127_5823322_5 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 598.0
PYH2_k127_5823322_6 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 459.0
PYH2_k127_5823322_7 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 353.0
PYH2_k127_5823322_8 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 310.0
PYH2_k127_5823322_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 309.0
PYH2_k127_5854087_0 Formyl transferase K19640 - - 2.587e-212 676.0
PYH2_k127_5854087_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 6.798e-209 682.0
PYH2_k127_5854087_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000007955 196.0
PYH2_k127_5854087_11 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000129 184.0
PYH2_k127_5854087_12 transcriptional regulators K03892 - - 0.000000000000000000000000000000000000486 143.0
PYH2_k127_5854087_13 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000007866 109.0
PYH2_k127_5854087_14 - - - - 0.0000000000000000000001563 104.0
PYH2_k127_5854087_15 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000007134 85.0
PYH2_k127_5854087_16 NHL repeat - - - 0.000000000000009587 85.0
PYH2_k127_5854087_17 PFAM UvrB UvrC protein - - - 0.000001354 59.0
PYH2_k127_5854087_2 Belongs to the HypD family K04654 - - 1.828e-201 632.0
PYH2_k127_5854087_4 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 533.0
PYH2_k127_5854087_5 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 522.0
PYH2_k127_5854087_6 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 499.0
PYH2_k127_5854087_7 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 423.0
PYH2_k127_5854087_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002062 249.0
PYH2_k127_5854087_9 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000004294 232.0
PYH2_k127_5860342_0 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 312.0
PYH2_k127_5860342_1 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000000001363 237.0
PYH2_k127_5860342_2 Rubredoxin - - - 0.00000000000000000000000000001554 119.0
PYH2_k127_5860342_3 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000000000000000000008978 119.0
PYH2_k127_5860342_4 Hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000006695 107.0
PYH2_k127_5863105_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 1.547e-288 894.0
PYH2_k127_5863105_1 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 353.0
PYH2_k127_5863105_10 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000587 103.0
PYH2_k127_5863105_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000007964 104.0
PYH2_k127_5863105_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000515 273.0
PYH2_k127_5863105_3 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000196 248.0
PYH2_k127_5863105_4 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
PYH2_k127_5863105_5 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000001182 190.0
PYH2_k127_5863105_6 oxidation protein K17227 - - 0.00000000000000000000000000000000000000003192 154.0
PYH2_k127_5863105_7 Thioredoxin-like - - - 0.00000000000000000000000000000000000002767 149.0
PYH2_k127_5863105_8 Peptidase S24-like - - - 0.000000000000000000000000000000002189 133.0
PYH2_k127_5863105_9 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000001199 111.0
PYH2_k127_5874969_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1250.0
PYH2_k127_5874969_1 PQQ-like domain K00114 - 1.1.2.8 8.245e-257 804.0
PYH2_k127_5874969_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000001109 275.0
PYH2_k127_5874969_11 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006797 259.0
PYH2_k127_5874969_12 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003639 243.0
PYH2_k127_5874969_13 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000006072 238.0
PYH2_k127_5874969_14 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000001275 214.0
PYH2_k127_5874969_15 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000001 195.0
PYH2_k127_5874969_16 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000004406 193.0
PYH2_k127_5874969_17 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000007139 181.0
PYH2_k127_5874969_18 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000007643 167.0
PYH2_k127_5874969_2 FMN-binding domain protein - - - 1.935e-230 734.0
PYH2_k127_5874969_3 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 4.034e-195 621.0
PYH2_k127_5874969_4 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 605.0
PYH2_k127_5874969_5 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 523.0
PYH2_k127_5874969_6 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 406.0
PYH2_k127_5874969_7 Quinohemoprotein amine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 399.0
PYH2_k127_5874969_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
PYH2_k127_5874969_9 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 300.0
PYH2_k127_5892489_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.881e-209 670.0
PYH2_k127_5892489_1 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 514.0
PYH2_k127_5892489_2 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000001462 207.0
PYH2_k127_5892489_3 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000174 181.0
PYH2_k127_5892489_4 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000007857 140.0
PYH2_k127_5892489_5 - - - - 0.000000000000000000000000000004513 126.0
PYH2_k127_5892489_6 SnoaL-like domain - - - 0.00000002788 62.0
PYH2_k127_5900448_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 606.0
PYH2_k127_5900448_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 562.0
PYH2_k127_5900448_10 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
PYH2_k127_5900448_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
PYH2_k127_5900448_12 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000001152 214.0
PYH2_k127_5900448_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000000009774 211.0
PYH2_k127_5900448_14 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000002899 197.0
PYH2_k127_5900448_15 - - - - 0.00000000000000000000000000000000000000000000000000139 195.0
PYH2_k127_5900448_16 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000225 139.0
PYH2_k127_5900448_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001054 121.0
PYH2_k127_5900448_18 Hsp20/alpha crystallin family - - - 0.0000000000000000000000001346 111.0
PYH2_k127_5900448_19 Prokaryotic cytochrome b561 K12262 - - 0.0002336 46.0
PYH2_k127_5900448_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 484.0
PYH2_k127_5900448_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 399.0
PYH2_k127_5900448_4 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 340.0
PYH2_k127_5900448_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 304.0
PYH2_k127_5900448_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
PYH2_k127_5900448_7 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001735 254.0
PYH2_k127_5900448_8 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000008424 231.0
PYH2_k127_5900448_9 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
PYH2_k127_5917182_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 561.0
PYH2_k127_5917182_1 Trypsin K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 493.0
PYH2_k127_5917182_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 388.0
PYH2_k127_5917182_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 362.0
PYH2_k127_5917182_4 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
PYH2_k127_5917182_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 345.0
PYH2_k127_5917182_6 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000001568 198.0
PYH2_k127_5917182_7 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000005876 157.0
PYH2_k127_5917182_8 - - - - 0.00000000000000000000000000000001861 132.0
PYH2_k127_5917182_9 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000000008733 111.0
PYH2_k127_5955221_0 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000001345 177.0
PYH2_k127_5955221_1 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000002103 123.0
PYH2_k127_5955221_3 chaperone-mediated protein folding - - - 0.00000000001525 76.0
PYH2_k127_5955221_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000007058 58.0
PYH2_k127_5956269_0 DNA polymerase K02337 - 2.7.7.7 0.0 1139.0
PYH2_k127_5956269_1 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 1.266e-313 968.0
PYH2_k127_5956269_10 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 482.0
PYH2_k127_5956269_11 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 408.0
PYH2_k127_5956269_12 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
PYH2_k127_5956269_13 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 343.0
PYH2_k127_5956269_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 322.0
PYH2_k127_5956269_15 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 316.0
PYH2_k127_5956269_16 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 318.0
PYH2_k127_5956269_17 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
PYH2_k127_5956269_18 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000003765 222.0
PYH2_k127_5956269_19 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000004261 222.0
PYH2_k127_5956269_2 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.271e-270 848.0
PYH2_k127_5956269_20 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000006767 214.0
PYH2_k127_5956269_21 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000003739 210.0
PYH2_k127_5956269_22 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.000000000000000000000000000000000000000000000000000009698 198.0
PYH2_k127_5956269_23 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000008867 182.0
PYH2_k127_5956269_24 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000002523 181.0
PYH2_k127_5956269_25 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000776 136.0
PYH2_k127_5956269_26 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000003672 141.0
PYH2_k127_5956269_27 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000009126 133.0
PYH2_k127_5956269_28 Cytochrome c K08738 - - 0.000000000000000000000000000005081 121.0
PYH2_k127_5956269_29 TonB-dependent hemoglobin transferrin lactoferrin K16087 - - 0.0000000000531 63.0
PYH2_k127_5956269_3 Bacterial protein of unknown function (DUF853) K06915 - - 6.777e-255 794.0
PYH2_k127_5956269_4 ribonuclease, Rne Rng family K08301 - - 1.403e-227 713.0
PYH2_k127_5956269_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 2.793e-216 687.0
PYH2_k127_5956269_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.239e-205 650.0
PYH2_k127_5956269_7 Belongs to the GARS family K01945 - 6.3.4.13 3.752e-203 642.0
PYH2_k127_5956269_8 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 571.0
PYH2_k127_5956269_9 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 502.0
PYH2_k127_5975149_0 TIGRFAM rfaE bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
PYH2_k127_5975149_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
PYH2_k127_5975149_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
PYH2_k127_5975149_3 PIN domain - - - 0.00000000000000000000000000116 116.0
PYH2_k127_5975149_4 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000004705 73.0
PYH2_k127_5975149_5 SpoVT / AbrB like domain - - - 0.00000000000332 70.0
PYH2_k127_6004103_0 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
PYH2_k127_6004103_1 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 346.0
PYH2_k127_6004103_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 306.0
PYH2_k127_6004103_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000001473 203.0
PYH2_k127_6004103_4 aldo keto reductase K19265 - - 0.000000000000000000000000000000000000000002888 156.0
PYH2_k127_6004103_5 PFAM Thioredoxin K00384 - 1.8.1.9 0.00000000000000000000000002298 114.0
PYH2_k127_6004103_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000001544 83.0
PYH2_k127_6012189_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 303.0
PYH2_k127_6012189_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000999 200.0
PYH2_k127_6018723_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 3.299e-215 682.0
PYH2_k127_6018723_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 1.084e-202 645.0
PYH2_k127_6018723_2 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 569.0
PYH2_k127_6018723_3 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 336.0
PYH2_k127_6018723_4 Phage integrase family - - - 0.00000000000000000000001444 101.0
PYH2_k127_6023818_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 532.0
PYH2_k127_6023818_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000008334 198.0
PYH2_k127_6023818_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000002207 145.0
PYH2_k127_6031509_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 9.05e-248 784.0
PYH2_k127_6031509_1 B12 binding domain - - - 1.249e-208 666.0
PYH2_k127_6031509_10 Outer membrane protein beta-barrel domain - - - 0.0000000000000001415 88.0
PYH2_k127_6031509_2 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 368.0
PYH2_k127_6031509_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000004589 231.0
PYH2_k127_6031509_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
PYH2_k127_6031509_5 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.000000000000000000000000000000000002938 141.0
PYH2_k127_6031509_6 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000000000003666 137.0
PYH2_k127_6031509_7 NHL repeat - - - 0.0000000000000000000000000000007144 121.0
PYH2_k127_6031509_8 amine dehydrogenase activity K13730 - - 0.000000000000000000000000000213 128.0
PYH2_k127_6031509_9 - - - - 0.000000000000000000005699 104.0
PYH2_k127_6043566_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.356e-253 786.0
PYH2_k127_6043566_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 327.0
PYH2_k127_6043566_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 299.0
PYH2_k127_6043566_3 mRNA binding - - - 0.000000000000000000000000007401 117.0
PYH2_k127_6043566_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000009349 110.0
PYH2_k127_6043566_5 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000003825 116.0
PYH2_k127_6046266_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006965 261.0
PYH2_k127_6046266_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000195 131.0
PYH2_k127_6046266_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000002695 73.0
PYH2_k127_6046266_3 - - - - 0.000000000001869 69.0
PYH2_k127_6046266_4 carboxylic ester hydrolase activity K03929 - - 0.0000000003465 68.0
PYH2_k127_6085279_0 B12 binding domain K00548 - 2.1.1.13 0.0 1827.0
PYH2_k127_6085279_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.814e-294 915.0
PYH2_k127_6085279_10 Protein of unknown function (DUF3567) - - - 0.0000000000000000000001598 108.0
PYH2_k127_6085279_11 cobalamin synthesis protein - - - 0.00000001421 61.0
PYH2_k127_6085279_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.637e-209 653.0
PYH2_k127_6085279_3 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 591.0
PYH2_k127_6085279_4 Beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 481.0
PYH2_k127_6085279_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 403.0
PYH2_k127_6085279_6 Tripartite ATP-independent periplasmic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH2_k127_6085279_7 sequence-specific DNA binding K05804,K13631,K13632,K18325,K19056 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009635,GO:0009636,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032787,GO:0032991,GO:0032993,GO:0035690,GO:0036245,GO:0042180,GO:0042182,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046185,GO:0046394,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051596,GO:0051716,GO:0060255,GO:0061727,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0072330,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:0140110,GO:1901363,GO:1901562,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006823 287.0
PYH2_k127_6085279_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000625 273.0
PYH2_k127_6085279_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000003291 167.0
PYH2_k127_6088754_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 446.0
PYH2_k127_6088754_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 384.0
PYH2_k127_6088754_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 323.0
PYH2_k127_6088754_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002058 297.0
PYH2_k127_6108134_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 589.0
PYH2_k127_6108134_1 Phosphoribulokinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 455.0
PYH2_k127_6108134_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 445.0
PYH2_k127_6108134_3 PFAM ribulose bisphosphate carboxylase small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000009139 226.0
PYH2_k127_6108134_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000007347 71.0
PYH2_k127_61431_0 Protein of unknown function - - - 2.734e-276 898.0
PYH2_k127_61431_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.193e-266 851.0
PYH2_k127_61431_10 Major facilitator superfamily - - - 0.000003079 51.0
PYH2_k127_61431_2 peptidase U62, modulator of DNA gyrase K03568 - - 4.889e-213 674.0
PYH2_k127_61431_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 506.0
PYH2_k127_61431_4 PFAM type II secretion system K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 395.0
PYH2_k127_61431_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
PYH2_k127_61431_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 374.0
PYH2_k127_61431_7 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
PYH2_k127_61431_8 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000002661 215.0
PYH2_k127_61431_9 TIR domain - - - 0.000000000000000000000000001777 129.0
PYH2_k127_6153799_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1300.0
PYH2_k127_6153799_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1262.0
PYH2_k127_6153799_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 463.0
PYH2_k127_6153799_11 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
PYH2_k127_6153799_12 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 394.0
PYH2_k127_6153799_13 mechanosensitive K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 349.0
PYH2_k127_6153799_14 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 289.0
PYH2_k127_6153799_15 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008366 286.0
PYH2_k127_6153799_16 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
PYH2_k127_6153799_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000005935 241.0
PYH2_k127_6153799_18 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001885 235.0
PYH2_k127_6153799_19 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
PYH2_k127_6153799_2 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.822e-239 743.0
PYH2_k127_6153799_20 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000001038 224.0
PYH2_k127_6153799_21 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
PYH2_k127_6153799_22 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000001383 193.0
PYH2_k127_6153799_23 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000001439 191.0
PYH2_k127_6153799_24 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000009304 169.0
PYH2_k127_6153799_25 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000001395 157.0
PYH2_k127_6153799_26 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000003375 139.0
PYH2_k127_6153799_27 Cold shock protein K03704 - - 0.0000000000000000000000000000000002042 134.0
PYH2_k127_6153799_28 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000003388 128.0
PYH2_k127_6153799_29 - - - - 0.000000000000000000000000000002905 127.0
PYH2_k127_6153799_3 DNA polymerase K00986 - 2.7.7.49 1.545e-225 708.0
PYH2_k127_6153799_30 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000001305 123.0
PYH2_k127_6153799_31 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000002995 101.0
PYH2_k127_6153799_32 cytochrome - - - 0.000000000000000000002817 98.0
PYH2_k127_6153799_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 530.0
PYH2_k127_6153799_5 sulfide dehydrogenase K05301 - 1.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 511.0
PYH2_k127_6153799_6 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 512.0
PYH2_k127_6153799_7 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 506.0
PYH2_k127_6153799_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 490.0
PYH2_k127_6153799_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 481.0
PYH2_k127_6163381_0 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 449.0
PYH2_k127_6172907_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 439.0
PYH2_k127_6172907_1 COG3436 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
PYH2_k127_6172907_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000481 102.0
PYH2_k127_6172907_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000021 63.0
PYH2_k127_6173316_0 AcrB/AcrD/AcrF family - - - 0.0 1234.0
PYH2_k127_6173316_1 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000009483 189.0
PYH2_k127_6194921_0 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000004114 173.0
PYH2_k127_6194921_1 Cas6 Crispr - - - 0.000000000000000000000000000000000000002172 157.0
PYH2_k127_6194921_2 - - - - 0.000000000000000000001394 97.0
PYH2_k127_6194921_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000006096 84.0
PYH2_k127_6224201_0 Protein of unknown function (DUF1329) - - - 1.11e-221 695.0
PYH2_k127_6224201_1 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 411.0
PYH2_k127_6224201_2 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
PYH2_k127_6224201_3 Methylamine dehydrogenase accessory protein MauD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007872 250.0
PYH2_k127_6224201_4 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000001762 145.0
PYH2_k127_6224201_5 Cytochrome c - - - 0.0000000000000000000000000001753 121.0
PYH2_k127_6224201_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001675 93.0
PYH2_k127_6308139_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1055.0
PYH2_k127_6308139_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 602.0
PYH2_k127_6308139_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000005284 124.0
PYH2_k127_6308139_11 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000001234 109.0
PYH2_k127_6308139_12 Histone methylation protein DOT1 - - - 0.00000000004607 67.0
PYH2_k127_6308139_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 479.0
PYH2_k127_6308139_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 462.0
PYH2_k127_6308139_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 373.0
PYH2_k127_6308139_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
PYH2_k127_6308139_6 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002926 259.0
PYH2_k127_6308139_7 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000009101 229.0
PYH2_k127_6308139_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
PYH2_k127_6308139_9 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000003937 138.0
PYH2_k127_6328183_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 314.0
PYH2_k127_6328183_1 - - - - 0.00000000000000000000002687 104.0
PYH2_k127_6328183_3 FAD dependent oxidoreductase - - - 0.00003002 48.0
PYH2_k127_63366_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 342.0
PYH2_k127_63366_1 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000000005217 232.0
PYH2_k127_63366_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
PYH2_k127_63366_3 ABC transporter, ATP-binding protein K02028 - 3.6.3.21 0.0000000000000000000000000000001292 135.0
PYH2_k127_63366_4 ABC transporter K02029,K10009 - - 0.0000000000000000000000009131 113.0
PYH2_k127_646895_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 499.0
PYH2_k127_646895_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 341.0
PYH2_k127_646895_10 - - - - 0.00000002635 58.0
PYH2_k127_646895_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 332.0
PYH2_k127_646895_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 334.0
PYH2_k127_646895_4 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 302.0
PYH2_k127_646895_5 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 258.0
PYH2_k127_646895_6 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001058 253.0
PYH2_k127_646895_7 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007506 249.0
PYH2_k127_646895_8 - - - - 0.0000000000000000000002625 104.0
PYH2_k127_646895_9 Protein of unknown function (DUF433) - - - 0.00000000000000007587 88.0
PYH2_k127_6482529_0 PFAM transposase, IS4 family protein K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 381.0
PYH2_k127_6482529_1 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000007604 189.0
PYH2_k127_6498557_0 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003245 242.0
PYH2_k127_6498557_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000005979 192.0
PYH2_k127_6498557_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000004617 83.0
PYH2_k127_6498557_3 - - - - 0.0000000000000007312 79.0
PYH2_k127_6515278_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 1.041e-231 726.0
PYH2_k127_6515278_1 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.241e-223 700.0
PYH2_k127_6515278_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 447.0
PYH2_k127_6515278_3 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001312 194.0
PYH2_k127_6515278_4 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000002158 146.0
PYH2_k127_6526361_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1024.0
PYH2_k127_6526361_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 8.319e-318 982.0
PYH2_k127_6526361_10 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
PYH2_k127_6526361_11 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
PYH2_k127_6526361_12 COG0451 Nucleoside-diphosphate-sugar epimerases K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
PYH2_k127_6526361_13 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
PYH2_k127_6526361_14 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
PYH2_k127_6526361_15 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000003058 192.0
PYH2_k127_6526361_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000005013 184.0
PYH2_k127_6526361_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000001099 185.0
PYH2_k127_6526361_18 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000178 163.0
PYH2_k127_6526361_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000003927 142.0
PYH2_k127_6526361_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.452e-282 873.0
PYH2_k127_6526361_20 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000437 127.0
PYH2_k127_6526361_21 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001144 111.0
PYH2_k127_6526361_22 ATP synthase I chain K02116 - - 0.00000000000000000408 88.0
PYH2_k127_6526361_23 Glucose / Sorbosone dehydrogenase - - - 0.0000000000007934 72.0
PYH2_k127_6526361_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.722e-275 850.0
PYH2_k127_6526361_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 423.0
PYH2_k127_6526361_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
PYH2_k127_6526361_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
PYH2_k127_6526361_7 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 398.0
PYH2_k127_6526361_8 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 387.0
PYH2_k127_6526361_9 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 344.0
PYH2_k127_6533902_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 610.0
PYH2_k127_6533902_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 586.0
PYH2_k127_6533902_10 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000001499 129.0
PYH2_k127_6533902_11 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000001591 122.0
PYH2_k127_6533902_12 cytochrome complex assembly - - - 0.000000000008605 76.0
PYH2_k127_6533902_2 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 493.0
PYH2_k127_6533902_3 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 374.0
PYH2_k127_6533902_4 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 348.0
PYH2_k127_6533902_5 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 266.0
PYH2_k127_6533902_6 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002369 257.0
PYH2_k127_6533902_7 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004727 256.0
PYH2_k127_6533902_8 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000008012 199.0
PYH2_k127_6533902_9 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000001389 196.0
PYH2_k127_6542200_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 9.433e-315 979.0
PYH2_k127_6542200_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.693e-224 700.0
PYH2_k127_6542200_10 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000995 168.0
PYH2_k127_6542200_11 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000016 147.0
PYH2_k127_6542200_12 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.0000000000000000000000002714 107.0
PYH2_k127_6542200_13 Trm112p-like protein K09791 - - 0.00000000000000000000006548 99.0
PYH2_k127_6542200_14 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000001013 71.0
PYH2_k127_6542200_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.104e-212 672.0
PYH2_k127_6542200_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 413.0
PYH2_k127_6542200_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 346.0
PYH2_k127_6542200_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 317.0
PYH2_k127_6542200_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 305.0
PYH2_k127_6542200_7 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002215 270.0
PYH2_k127_6542200_8 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000001932 223.0
PYH2_k127_6542200_9 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000003564 213.0
PYH2_k127_6542507_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 4.849e-196 619.0
PYH2_k127_6542507_1 PFAM transposase, IS111A IS1328 IS1533 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 481.0
PYH2_k127_6542507_2 IS66 C-terminal element - - - 0.0000000000000000000000000000000000000000000000000000000003147 209.0
PYH2_k127_6542507_3 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000000000000005391 190.0
PYH2_k127_6542507_4 COG3436 Transposase and inactivated derivatives K07484 - - 0.00000000000000000000000000000000000000000000002102 178.0
PYH2_k127_6542507_5 IS66 C-terminal element - - - 0.0000000000107 66.0
PYH2_k127_6542507_6 COG2801 Transposase and inactivated derivatives - - - 0.0000008307 55.0
PYH2_k127_6544907_0 Belongs to the 'phage' integrase family - - - 6.308e-239 742.0
PYH2_k127_6544907_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 589.0
PYH2_k127_6544907_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 493.0
PYH2_k127_6544907_3 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 432.0
PYH2_k127_6544907_4 PFAM helix-turn-helix domain protein - - - 0.0000000000003594 73.0
PYH2_k127_6544907_5 ABC transporter substrate binding protein K01989 - - 0.000000938 57.0
PYH2_k127_6547986_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 1e-323 996.0
PYH2_k127_6547986_1 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 1.666e-206 647.0
PYH2_k127_6547986_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 460.0
PYH2_k127_6547986_3 Succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 334.0
PYH2_k127_6547986_4 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005998 279.0
PYH2_k127_6547986_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001164 178.0
PYH2_k127_6547986_6 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.0000000000000000000000000000000000000000004701 160.0
PYH2_k127_6547986_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000003516 109.0
PYH2_k127_6558686_0 DNA helicase K03657 - 3.6.4.12 8.901e-295 919.0
PYH2_k127_6558686_1 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 365.0
PYH2_k127_6558686_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 290.0
PYH2_k127_6558686_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000001312 139.0
PYH2_k127_6558686_4 Addiction module toxin, RelE StbE family K07334 - - 0.0000000000000000000000000000000000327 136.0
PYH2_k127_6558686_5 Tetratricopeptide repeat K12284 - - 0.00004539 53.0
PYH2_k127_6589649_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 3e-323 995.0
PYH2_k127_6589649_1 peptidase dimerisation domain protein - - - 2.892e-207 651.0
PYH2_k127_6589649_10 sodium:proton antiporter activity K03316 - - 0.00006026 50.0
PYH2_k127_6589649_2 deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 588.0
PYH2_k127_6589649_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 508.0
PYH2_k127_6589649_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 307.0
PYH2_k127_6589649_5 Nucleoside-binding outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000003736 221.0
PYH2_k127_6589649_6 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000000000001052 184.0
PYH2_k127_6589649_7 FCD - - - 0.0000000000000000000000000000000000000000000000006677 184.0
PYH2_k127_6589649_8 Glycine-zipper domain - - - 0.0000000000318 67.0
PYH2_k127_6589649_9 Domain of unknown function (DUF4124) - - - 0.000002829 55.0
PYH2_k127_6594419_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1191.0
PYH2_k127_6594419_1 Elongation factor G, domain IV K02355 - - 2.286e-307 955.0
PYH2_k127_6594419_10 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 306.0
PYH2_k127_6594419_11 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002156 279.0
PYH2_k127_6594419_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
PYH2_k127_6594419_13 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000006812 165.0
PYH2_k127_6594419_14 Putative transposase - - - 0.0000000000000000000000001805 123.0
PYH2_k127_6594419_2 Aldehyde dehydrogenase family - - - 2.626e-212 667.0
PYH2_k127_6594419_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 599.0
PYH2_k127_6594419_4 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 558.0
PYH2_k127_6594419_5 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 467.0
PYH2_k127_6594419_6 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 449.0
PYH2_k127_6594419_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 387.0
PYH2_k127_6594419_8 Peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 334.0
PYH2_k127_6594419_9 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 327.0
PYH2_k127_6596385_0 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 432.0
PYH2_k127_6596385_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 433.0
PYH2_k127_6596385_2 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 308.0
PYH2_k127_6596385_3 GYD domain - - - 0.0000000000000000000000000001378 117.0
PYH2_k127_6596385_4 - - - - 0.0000000000000000004803 89.0
PYH2_k127_6596385_5 SnoaL-like domain - - - 0.00000002989 64.0
PYH2_k127_6636581_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.096e-219 688.0
PYH2_k127_6636581_1 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 554.0
PYH2_k127_6636581_10 - - - - 0.00000000001548 65.0
PYH2_k127_6636581_2 Dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 515.0
PYH2_k127_6636581_3 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 505.0
PYH2_k127_6636581_4 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
PYH2_k127_6636581_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 349.0
PYH2_k127_6636581_6 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 293.0
PYH2_k127_6636581_7 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000003185 235.0
PYH2_k127_6636581_8 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000007846 234.0
PYH2_k127_6636581_9 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000002957 198.0
PYH2_k127_6643860_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.934e-270 843.0
PYH2_k127_6643860_1 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001187 218.0
PYH2_k127_6643860_2 - - - - 0.00000000000002216 81.0
PYH2_k127_6668078_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.337e-309 968.0
PYH2_k127_6668078_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.18e-268 831.0
PYH2_k127_6668078_10 dehydrogenase - - - 0.00006767 49.0
PYH2_k127_6668078_11 COG COG3345 Alpha-galactosidase - - - 0.0005285 46.0
PYH2_k127_6668078_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 559.0
PYH2_k127_6668078_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 362.0
PYH2_k127_6668078_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
PYH2_k127_6668078_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
PYH2_k127_6668078_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000003401 180.0
PYH2_k127_6668078_7 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000001835 177.0
PYH2_k127_6668078_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000312 165.0
PYH2_k127_6668078_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000003624 106.0
PYH2_k127_6674931_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.545e-284 900.0
PYH2_k127_6674931_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.714e-198 627.0
PYH2_k127_6674931_10 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000002649 240.0
PYH2_k127_6674931_11 SpoU rRNA Methylase family K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
PYH2_k127_6674931_12 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000001811 221.0
PYH2_k127_6674931_13 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000002526 155.0
PYH2_k127_6674931_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001617 143.0
PYH2_k127_6674931_15 peptidyl-prolyl K03775 - 5.2.1.8 0.00000000000000000000000000000000003095 141.0
PYH2_k127_6674931_16 - - - - 0.00000000498 65.0
PYH2_k127_6674931_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 559.0
PYH2_k127_6674931_3 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 389.0
PYH2_k127_6674931_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
PYH2_k127_6674931_5 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 372.0
PYH2_k127_6674931_6 Sugar kinases ribokinase family K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 349.0
PYH2_k127_6674931_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 324.0
PYH2_k127_6674931_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000154 274.0
PYH2_k127_6674931_9 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000036 250.0
PYH2_k127_6686389_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.399e-269 840.0
PYH2_k127_6686389_1 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002357 282.0
PYH2_k127_6686644_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.807e-239 758.0
PYH2_k127_6686644_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 593.0
PYH2_k127_6686644_10 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000005453 154.0
PYH2_k127_6686644_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000004181 151.0
PYH2_k127_6686644_12 - - - - 0.000000000000000000000105 104.0
PYH2_k127_6686644_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000002885 81.0
PYH2_k127_6686644_14 Dienelactone hydrolase family - - - 0.00000000007907 70.0
PYH2_k127_6686644_15 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0008015 48.0
PYH2_k127_6686644_2 Pfam:DUF989 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 583.0
PYH2_k127_6686644_3 Basic membrane lipoprotein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 529.0
PYH2_k127_6686644_4 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 470.0
PYH2_k127_6686644_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 451.0
PYH2_k127_6686644_6 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 318.0
PYH2_k127_6686644_7 Carboxylesterase family K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
PYH2_k127_6686644_8 signal transduction protein containing sensor and EAL - - - 0.0000000000000000000000000000000000000000000000003988 179.0
PYH2_k127_6686644_9 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000005917 174.0
PYH2_k127_6738201_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 441.0
PYH2_k127_6738201_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
PYH2_k127_6738201_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000004986 227.0
PYH2_k127_6738201_3 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
PYH2_k127_6738201_4 - - - - 0.00000000000000000000002195 108.0
PYH2_k127_6784620_0 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 490.0
PYH2_k127_6784620_1 abc transporter atp-binding protein K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 399.0
PYH2_k127_6784620_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
PYH2_k127_6784620_3 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
PYH2_k127_6784620_4 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.00000000000000000000000000000000000000000005098 164.0
PYH2_k127_6784620_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000006621 115.0
PYH2_k127_6803786_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 516.0
PYH2_k127_6803786_1 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
PYH2_k127_6803786_2 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000003467 176.0
PYH2_k127_6803786_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000005345 158.0
PYH2_k127_6803786_4 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.000000000000000000006986 92.0
PYH2_k127_6803786_5 NnrS protein K07234 - - 0.000000000000000008566 88.0
PYH2_k127_6812637_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007973 252.0
PYH2_k127_6812637_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000001539 183.0
PYH2_k127_6812637_2 Aspartyl protease K06985 - - 0.00000000000000001128 93.0
PYH2_k127_6816389_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 518.0
PYH2_k127_6816389_1 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 376.0
PYH2_k127_6822397_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.086e-279 879.0
PYH2_k127_6822397_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 406.0
PYH2_k127_6822397_10 - - - - 0.0000000000000000000000000000461 117.0
PYH2_k127_6822397_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
PYH2_k127_6822397_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000001502 207.0
PYH2_k127_6822397_4 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
PYH2_k127_6822397_5 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH2_k127_6822397_6 PIN domain - - - 0.0000000000000000000000000000000000000000000116 169.0
PYH2_k127_6822397_7 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000001843 152.0
PYH2_k127_6822397_9 toxin-antitoxin pair type II binding K19156 GO:0001558,GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0040008,GO:0042802,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000002674 128.0
PYH2_k127_6858739_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 5.814e-262 813.0
PYH2_k127_6858739_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 7.029e-212 662.0
PYH2_k127_6858739_2 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 1.826e-201 632.0
PYH2_k127_6858739_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 539.0
PYH2_k127_6858739_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 496.0
PYH2_k127_6858739_5 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 473.0
PYH2_k127_6858739_6 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000008379 74.0
PYH2_k127_6860897_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 6.01e-220 691.0
PYH2_k127_6860897_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 531.0
PYH2_k127_6860897_10 Belongs to the 'phage' integrase family - - - 0.00000001946 62.0
PYH2_k127_6860897_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 525.0
PYH2_k127_6860897_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
PYH2_k127_6860897_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000003352 266.0
PYH2_k127_6860897_5 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000002538 233.0
PYH2_k127_6860897_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000006812 179.0
PYH2_k127_6860897_7 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000000000000008726 144.0
PYH2_k127_6860897_8 protein domain associated with - - - 0.0000000000000000000000000000000001305 144.0
PYH2_k127_6860897_9 FR47-like protein K06976 - - 0.0000000000008401 73.0
PYH2_k127_6862350_0 Transketolase, pyrimidine binding domain K21417 - - 1.393e-194 609.0
PYH2_k127_6862350_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
PYH2_k127_6862350_2 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 548.0
PYH2_k127_6862350_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 532.0
PYH2_k127_6862350_4 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 480.0
PYH2_k127_6862350_5 lipoate-protein ligase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 252.0
PYH2_k127_6862350_6 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000005754 156.0
PYH2_k127_6862350_7 - - - - 0.00000000000003941 74.0
PYH2_k127_6866248_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1429.0
PYH2_k127_6866248_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1301.0
PYH2_k127_6866248_10 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 566.0
PYH2_k127_6866248_11 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 502.0
PYH2_k127_6866248_12 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 483.0
PYH2_k127_6866248_13 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 482.0
PYH2_k127_6866248_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 444.0
PYH2_k127_6866248_15 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
PYH2_k127_6866248_16 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 408.0
PYH2_k127_6866248_17 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 402.0
PYH2_k127_6866248_18 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 370.0
PYH2_k127_6866248_19 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 338.0
PYH2_k127_6866248_2 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 2.152e-238 743.0
PYH2_k127_6866248_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 320.0
PYH2_k127_6866248_21 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
PYH2_k127_6866248_22 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 304.0
PYH2_k127_6866248_23 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
PYH2_k127_6866248_24 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
PYH2_k127_6866248_25 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006187 299.0
PYH2_k127_6866248_26 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
PYH2_k127_6866248_27 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000003621 262.0
PYH2_k127_6866248_28 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000007543 242.0
PYH2_k127_6866248_29 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
PYH2_k127_6866248_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.173e-226 708.0
PYH2_k127_6866248_30 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
PYH2_k127_6866248_31 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000287 207.0
PYH2_k127_6866248_32 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000002625 183.0
PYH2_k127_6866248_33 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000003788 149.0
PYH2_k127_6866248_34 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000009614 148.0
PYH2_k127_6866248_35 Protein of unknown function (DUF465) - - - 0.0000000000000002821 80.0
PYH2_k127_6866248_36 - - - - 0.000000000000005938 85.0
PYH2_k127_6866248_38 - - - - 0.0003345 45.0
PYH2_k127_6866248_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.901e-222 694.0
PYH2_k127_6866248_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.06e-217 683.0
PYH2_k127_6866248_6 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 9.954e-210 668.0
PYH2_k127_6866248_7 helicase K03722 - 3.6.4.12 2.855e-199 642.0
PYH2_k127_6866248_8 Belongs to the thiolase family K00626 - 2.3.1.9 7.479e-199 627.0
PYH2_k127_6866248_9 Belongs to the thiolase family K00626 - 2.3.1.9 8.355e-195 613.0
PYH2_k127_6873530_0 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001689 247.0
PYH2_k127_6873530_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001664 138.0
PYH2_k127_6873530_2 toxin-antitoxin pair type II binding - - - 0.000000000000000126 82.0
PYH2_k127_6873530_3 trans-aconitate 2-methyltransferase activity K00563,K02169,K16868 - 2.1.1.187,2.1.1.197,2.1.1.265 0.0000000000000003179 89.0
PYH2_k127_6873530_4 Coenzyme A transferase K01026 - 2.8.3.1 0.00000000000000287 76.0
PYH2_k127_6875067_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 358.0
PYH2_k127_6875067_1 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.00000000000000000000000000000000000000000000003284 175.0
PYH2_k127_6875067_2 plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000000001166 160.0
PYH2_k127_6875067_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000001006 140.0
PYH2_k127_6875067_4 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000003558 108.0
PYH2_k127_6877906_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 568.0
PYH2_k127_6877906_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 554.0
PYH2_k127_6877906_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 460.0
PYH2_k127_6877906_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 383.0
PYH2_k127_6877906_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 327.0
PYH2_k127_6877906_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
PYH2_k127_6877906_6 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
PYH2_k127_6877906_7 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000005715 175.0
PYH2_k127_6877906_8 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000007887 145.0
PYH2_k127_6877906_9 Protein of unknown function (DUF2905) - - - 0.00000000000000017 80.0
PYH2_k127_6883262_0 transport system, fused permease components - - - 5.537e-275 862.0
PYH2_k127_6883262_1 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000003354 97.0
PYH2_k127_6939433_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1037.0
PYH2_k127_6939433_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 5.447e-296 929.0
PYH2_k127_6939433_2 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 1.121e-212 684.0
PYH2_k127_6939433_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 560.0
PYH2_k127_6939433_4 PFAM extracellular solute-binding protein family 1 K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 394.0
PYH2_k127_6939433_5 Belongs to the ABC transporter superfamily K10111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002731 275.0
PYH2_k127_6939433_6 - - - - 0.0000000000000000000000000000000000000000001626 172.0
PYH2_k127_6970260_0 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 377.0
PYH2_k127_6970260_1 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101,K16422 - 1.1.2.3,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 326.0
PYH2_k127_698098_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 455.0
PYH2_k127_698098_1 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 368.0
PYH2_k127_6993071_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 488.0
PYH2_k127_6993071_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 419.0
PYH2_k127_700364_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.639e-238 742.0
PYH2_k127_700364_1 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 404.0
PYH2_k127_700364_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 404.0
PYH2_k127_700364_3 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 374.0
PYH2_k127_700364_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001714 208.0
PYH2_k127_700364_5 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000002798 185.0
PYH2_k127_700364_6 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000872 130.0
PYH2_k127_7021340_0 AMP-binding enzyme C-terminal domain - - - 2.351e-228 717.0
PYH2_k127_7021340_1 AMP-binding enzyme C-terminal domain K18661 - - 4.052e-217 686.0
PYH2_k127_7021340_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 445.0
PYH2_k127_7021340_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 437.0
PYH2_k127_7021340_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 384.0
PYH2_k127_7021340_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005282 258.0
PYH2_k127_7021340_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000099 99.0
PYH2_k127_7051326_0 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 518.0
PYH2_k127_7051326_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 497.0
PYH2_k127_7051326_2 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 399.0
PYH2_k127_7051326_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 368.0
PYH2_k127_7051326_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 319.0
PYH2_k127_7051326_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 319.0
PYH2_k127_7051326_6 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
PYH2_k127_7051326_7 SnoaL-like domain - - - 0.0000000000000000000000000000001423 129.0
PYH2_k127_7051326_8 Zinc-finger domain - - - 0.000000000000000000000001159 106.0
PYH2_k127_7051326_9 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000009149 101.0
PYH2_k127_7151842_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1635.0
PYH2_k127_7151842_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 494.0
PYH2_k127_7151842_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000003695 119.0
PYH2_k127_7151842_2 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 447.0
PYH2_k127_7151842_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 442.0
PYH2_k127_7151842_4 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 337.0
PYH2_k127_7151842_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 311.0
PYH2_k127_7151842_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 306.0
PYH2_k127_7151842_7 Domain of unknown function (DUF309) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003106 231.0
PYH2_k127_7151842_8 Histidine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000103 223.0
PYH2_k127_7151842_9 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000001429 154.0
PYH2_k127_716305_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1759.0
PYH2_k127_716305_1 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 8.428e-217 681.0
PYH2_k127_716305_10 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 349.0
PYH2_k127_716305_11 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 300.0
PYH2_k127_716305_12 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001436 225.0
PYH2_k127_716305_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000001732 203.0
PYH2_k127_716305_14 Thioesterase K07107,K12500 - - 0.000000000000000000000000000000000000000000000000001073 191.0
PYH2_k127_716305_15 Ribbon-helix-helix domain - - - 0.000000000000000000000000000000000000000003401 157.0
PYH2_k127_716305_16 NUDIX domain - - - 0.00000000000000000000000000002962 124.0
PYH2_k127_716305_17 SMART Cold shock protein K03704 - - 0.000000000000000000000000001916 112.0
PYH2_k127_716305_18 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000001388 70.0
PYH2_k127_716305_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 1.779e-209 659.0
PYH2_k127_716305_3 Transketolase, C-terminal domain K00167 - 1.2.4.4 7.289e-195 612.0
PYH2_k127_716305_4 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 572.0
PYH2_k127_716305_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 564.0
PYH2_k127_716305_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 541.0
PYH2_k127_716305_7 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 500.0
PYH2_k127_716305_8 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 396.0
PYH2_k127_716305_9 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 389.0
PYH2_k127_7208318_0 Molecular chaperone. Has ATPase activity K04079 - - 1.266e-298 927.0
PYH2_k127_7208318_1 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 577.0
PYH2_k127_7208318_10 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
PYH2_k127_7208318_11 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000004204 251.0
PYH2_k127_7208318_12 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000005363 251.0
PYH2_k127_7208318_13 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000002047 246.0
PYH2_k127_7208318_14 glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
PYH2_k127_7208318_15 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000004192 206.0
PYH2_k127_7208318_16 Copper resistance protein D - - - 0.0000000000000000000000000000000001429 137.0
PYH2_k127_7208318_17 Cytochrome c - - - 0.00000000000000000000000000003538 121.0
PYH2_k127_7208318_18 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000001563 120.0
PYH2_k127_7208318_19 Cytochrome c, class I - - - 0.0000000000000000000000000002593 117.0
PYH2_k127_7208318_2 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 511.0
PYH2_k127_7208318_20 - - - - 0.0000000000004358 72.0
PYH2_k127_7208318_21 Receptor family ligand binding region K01999 - - 0.0000000000099 72.0
PYH2_k127_7208318_3 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 489.0
PYH2_k127_7208318_4 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 433.0
PYH2_k127_7208318_5 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 405.0
PYH2_k127_7208318_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 293.0
PYH2_k127_7208318_7 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001415 306.0
PYH2_k127_7208318_8 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007586 279.0
PYH2_k127_7208318_9 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002709 265.0
PYH2_k127_7236115_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.884e-247 776.0
PYH2_k127_7236115_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 395.0
PYH2_k127_7236115_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000009052 160.0
PYH2_k127_7236115_11 Domain of unknown function (DUF4845) - - - 0.00000000000000000000429 97.0
PYH2_k127_7236115_12 Phage integrase family - - - 0.0000000000009053 74.0
PYH2_k127_7236115_14 transferase activity, transferring glycosyl groups - - - 0.000003682 48.0
PYH2_k127_7236115_2 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 391.0
PYH2_k127_7236115_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
PYH2_k127_7236115_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
PYH2_k127_7236115_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
PYH2_k127_7236115_6 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 307.0
PYH2_k127_7236115_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002273 278.0
PYH2_k127_7236115_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000001377 254.0
PYH2_k127_7236115_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000002909 160.0
PYH2_k127_7251800_0 peptidase M24 K01262 - 3.4.11.9 2.05e-241 759.0
PYH2_k127_7251800_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
PYH2_k127_7251800_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
PYH2_k127_7251800_11 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
PYH2_k127_7251800_12 Histidine kinase K07648 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005726 260.0
PYH2_k127_7251800_13 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
PYH2_k127_7251800_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001698 136.0
PYH2_k127_7251800_15 Cold shock K03704 - - 0.000000000000000000000000009522 109.0
PYH2_k127_7251800_16 RsgA GTPase K06949 - 3.1.3.100 0.000001536 51.0
PYH2_k127_7251800_17 - - - - 0.00002471 48.0
PYH2_k127_7251800_2 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 412.0
PYH2_k127_7251800_3 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 395.0
PYH2_k127_7251800_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 396.0
PYH2_k127_7251800_5 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
PYH2_k127_7251800_6 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
PYH2_k127_7251800_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 374.0
PYH2_k127_7251800_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 317.0
PYH2_k127_7251800_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
PYH2_k127_7295165_0 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 383.0
PYH2_k127_7295165_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000001002 127.0
PYH2_k127_7295165_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000007684 117.0
PYH2_k127_7302720_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 4.054e-218 693.0
PYH2_k127_7302720_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.134e-199 631.0
PYH2_k127_7302720_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 408.0
PYH2_k127_7302720_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 348.0
PYH2_k127_7302720_4 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
PYH2_k127_7302720_5 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
PYH2_k127_7302720_6 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
PYH2_k127_7302720_7 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000002644 236.0
PYH2_k127_7302720_8 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000003189 182.0
PYH2_k127_7378838_0 surface antigen variable number repeat protein K07001 - - 8.75e-207 655.0
PYH2_k127_7378838_1 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000000000537 168.0
PYH2_k127_7378838_2 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000105 132.0
PYH2_k127_7378838_3 Sodium Bile acid symporter family - - - 0.0000000000000000007396 96.0
PYH2_k127_747190_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 3.172e-239 761.0
PYH2_k127_747190_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.685e-207 651.0
PYH2_k127_747190_10 PFAM extracellular solute-binding protein family 1 K17315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 312.0
PYH2_k127_747190_11 - - - - 0.00000000000000000000000000000000000000000000008941 175.0
PYH2_k127_747190_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000004134 126.0
PYH2_k127_747190_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001656 109.0
PYH2_k127_747190_14 metal cluster binding - - - 0.0000000000000000000009446 102.0
PYH2_k127_747190_15 Sel1 domain protein repeat-containing protein K07126 - - 0.00000008827 63.0
PYH2_k127_747190_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 576.0
PYH2_k127_747190_3 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 564.0
PYH2_k127_747190_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 548.0
PYH2_k127_747190_5 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 515.0
PYH2_k127_747190_6 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 505.0
PYH2_k127_747190_7 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 496.0
PYH2_k127_747190_8 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 477.0
PYH2_k127_747190_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 379.0
PYH2_k127_7487875_0 Penicillin amidase K01434 - 3.5.1.11 5.514e-320 1004.0
PYH2_k127_7487875_1 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 459.0
PYH2_k127_7487875_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002419 243.0
PYH2_k127_7487875_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000005079 228.0
PYH2_k127_7487875_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000132 187.0
PYH2_k127_7487875_5 DDE superfamily endonuclease K07494 - - 0.0000000000181 67.0
PYH2_k127_7487875_6 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.00000000004252 75.0
PYH2_k127_7487875_7 PFAM HNH endonuclease - - - 0.000001436 56.0
PYH2_k127_7513524_0 FAD dependent oxidoreductase K07256 - - 7.103e-255 791.0
PYH2_k127_7513524_1 Aminotransferase K00375 - - 1.151e-209 665.0
PYH2_k127_7513524_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 574.0
PYH2_k127_7513524_3 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 508.0
PYH2_k127_7513524_4 ABC transporter K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 464.0
PYH2_k127_7513524_5 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 451.0
PYH2_k127_7513524_6 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
PYH2_k127_7513524_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000001263 108.0
PYH2_k127_7515120_0 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 524.0
PYH2_k127_7515120_1 - - - - 0.0000000000000000000003994 102.0
PYH2_k127_7525534_0 Ammonium transporter K03320 - - 3.404e-230 726.0
PYH2_k127_7525534_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 7.947e-199 629.0
PYH2_k127_7525534_10 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 316.0
PYH2_k127_7525534_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
PYH2_k127_7525534_12 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000249 261.0
PYH2_k127_7525534_13 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005008 243.0
PYH2_k127_7525534_14 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003228 237.0
PYH2_k127_7525534_15 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
PYH2_k127_7525534_16 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
PYH2_k127_7525534_17 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000000007525 152.0
PYH2_k127_7525534_18 phosphoribosyl transferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000001511 125.0
PYH2_k127_7525534_19 - - - - 0.0000000000000000000000000002662 123.0
PYH2_k127_7525534_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.868e-194 613.0
PYH2_k127_7525534_20 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000001378 114.0
PYH2_k127_7525534_21 Membrane fusogenic activity K09806 - - 0.0000000000000000001933 90.0
PYH2_k127_7525534_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
PYH2_k127_7525534_4 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 574.0
PYH2_k127_7525534_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 548.0
PYH2_k127_7525534_6 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 471.0
PYH2_k127_7525534_7 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
PYH2_k127_7525534_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 368.0
PYH2_k127_7525534_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 359.0
PYH2_k127_7542679_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1480.0
PYH2_k127_7542679_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.994e-251 779.0
PYH2_k127_7542679_10 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000003205 108.0
PYH2_k127_7542679_11 Cysteine-rich secretory protein family - - - 0.00000000000000000000008583 106.0
PYH2_k127_7542679_12 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000003154 98.0
PYH2_k127_7542679_13 MlaD protein K02067 - - 0.0000000000007996 79.0
PYH2_k127_7542679_14 LuxR family transcriptional regulator K03556 - - 0.0000000001038 65.0
PYH2_k127_7542679_15 - - - - 0.0005382 51.0
PYH2_k127_7542679_2 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.467e-245 765.0
PYH2_k127_7542679_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 567.0
PYH2_k127_7542679_4 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
PYH2_k127_7542679_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
PYH2_k127_7542679_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 280.0
PYH2_k127_7542679_7 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.00000000000000000000000000000000000000001001 156.0
PYH2_k127_7542679_8 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000003095 154.0
PYH2_k127_7542679_9 Psort location Extracellular, score - - - 0.0000000000000000000000000221 118.0
PYH2_k127_7550353_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1212.0
PYH2_k127_7550353_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1030.0
PYH2_k127_7550353_10 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
PYH2_k127_7550353_2 FAD dependent oxidoreductase K13796 - - 5.943e-236 736.0
PYH2_k127_7550353_3 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 2.921e-218 689.0
PYH2_k127_7550353_4 CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 610.0
PYH2_k127_7550353_5 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 385.0
PYH2_k127_7550353_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
PYH2_k127_7550353_7 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001346 269.0
PYH2_k127_7550353_8 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 261.0
PYH2_k127_7550353_9 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000265 246.0
PYH2_k127_7568328_0 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 413.0
PYH2_k127_7568328_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 344.0
PYH2_k127_7568328_10 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000001347 128.0
PYH2_k127_7568328_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000003478 97.0
PYH2_k127_7568328_12 - - - - 0.000611 46.0
PYH2_k127_7568328_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
PYH2_k127_7568328_3 Biopolymer transport K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
PYH2_k127_7568328_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001521 278.0
PYH2_k127_7568328_5 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 261.0
PYH2_k127_7568328_6 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001311 229.0
PYH2_k127_7568328_7 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000001148 194.0
PYH2_k127_7568328_8 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000000003469 156.0
PYH2_k127_7568328_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000003611 158.0
PYH2_k127_7570609_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 542.0
PYH2_k127_7570609_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 484.0
PYH2_k127_7570609_10 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000001977 158.0
PYH2_k127_7570609_11 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000003372 135.0
PYH2_k127_7570609_12 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000001126 117.0
PYH2_k127_7570609_13 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000001331 121.0
PYH2_k127_7570609_14 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000001648 119.0
PYH2_k127_7570609_15 PFAM MaoC domain protein dehydratase - - - 0.000000000000000428 80.0
PYH2_k127_7570609_16 - - - - 0.00000000002905 70.0
PYH2_k127_7570609_2 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 331.0
PYH2_k127_7570609_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 305.0
PYH2_k127_7570609_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
PYH2_k127_7570609_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000005039 216.0
PYH2_k127_7570609_7 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000003744 189.0
PYH2_k127_7570609_8 regulatory - - - 0.000000000000000000000000000000000000000000000000001463 190.0
PYH2_k127_7570609_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000002978 179.0
PYH2_k127_7628519_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.831e-199 639.0
PYH2_k127_7628519_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 477.0
PYH2_k127_7628519_10 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000000004052 167.0
PYH2_k127_7628519_11 Major facilitator superfamily K07552,K18552 - - 0.000000000000000000000003326 109.0
PYH2_k127_7628519_12 Transposase - - - 0.00000000004286 63.0
PYH2_k127_7628519_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
PYH2_k127_7628519_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 470.0
PYH2_k127_7628519_4 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 390.0
PYH2_k127_7628519_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 306.0
PYH2_k127_7628519_6 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
PYH2_k127_7628519_7 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
PYH2_k127_7628519_8 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000000005347 188.0
PYH2_k127_7628519_9 WHG domain - - - 0.000000000000000000000000000000000000000000000001516 181.0
PYH2_k127_7670601_0 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 355.0
PYH2_k127_7670601_1 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 311.0
PYH2_k127_7670601_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000002752 236.0
PYH2_k127_7687081_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 447.0
PYH2_k127_7687081_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
PYH2_k127_7687081_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000004536 141.0
PYH2_k127_7687081_3 PFAM cytochrome c - - - 0.00000000000000000000000000001742 124.0
PYH2_k127_7690509_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1309.0
PYH2_k127_7690509_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1283.0
PYH2_k127_7690509_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 415.0
PYH2_k127_7690509_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 393.0
PYH2_k127_7690509_12 Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
PYH2_k127_7690509_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 358.0
PYH2_k127_7690509_14 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 331.0
PYH2_k127_7690509_15 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
PYH2_k127_7690509_16 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002064 267.0
PYH2_k127_7690509_17 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002091 273.0
PYH2_k127_7690509_18 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000001265 261.0
PYH2_k127_7690509_19 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002578 256.0
PYH2_k127_7690509_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 7.018e-269 831.0
PYH2_k127_7690509_20 NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000005548 223.0
PYH2_k127_7690509_21 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
PYH2_k127_7690509_22 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000002546 187.0
PYH2_k127_7690509_23 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000818 178.0
PYH2_k127_7690509_24 Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000006067 173.0
PYH2_k127_7690509_25 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000004928 176.0
PYH2_k127_7690509_26 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000009195 174.0
PYH2_k127_7690509_27 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000006932 166.0
PYH2_k127_7690509_28 - - - - 0.000000000000000000000000000000000000000002177 159.0
PYH2_k127_7690509_29 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000001696 152.0
PYH2_k127_7690509_3 Tripartite tricarboxylate transporter TctA family K07793 - - 1.982e-244 762.0
PYH2_k127_7690509_30 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000001016 124.0
PYH2_k127_7690509_31 - - - - 0.000000000000000000000000001374 115.0
PYH2_k127_7690509_32 FixH family K09926 - - 0.000000000000000000000000007601 117.0
PYH2_k127_7690509_33 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000005397 98.0
PYH2_k127_7690509_34 cellulase activity - - - 0.00000000000000000003907 105.0
PYH2_k127_7690509_35 Cbb3-type cytochrome oxidase K00407 - - 0.000000000000002591 76.0
PYH2_k127_7690509_36 cytochrome oxidase maturation protein cbb3-type - - - 0.000000008964 59.0
PYH2_k127_7690509_37 Protein of unknown function (DUF1223) - - - 0.0002197 47.0
PYH2_k127_7690509_4 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 1.095e-219 694.0
PYH2_k127_7690509_5 Domain of unknown function (DUF5117) - - - 3.634e-210 687.0
PYH2_k127_7690509_6 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 594.0
PYH2_k127_7690509_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 586.0
PYH2_k127_7690509_8 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 585.0
PYH2_k127_7690509_9 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 499.0
PYH2_k127_7691744_0 Histidine kinase K02487,K06596 - - 0.0 1263.0
PYH2_k127_7691744_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 1.456e-207 653.0
PYH2_k127_7691744_10 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000001886 245.0
PYH2_k127_7691744_11 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
PYH2_k127_7691744_12 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000004054 215.0
PYH2_k127_7691744_13 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000003012 186.0
PYH2_k127_7691744_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000002075 172.0
PYH2_k127_7691744_15 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000003627 177.0
PYH2_k127_7691744_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000001306 176.0
PYH2_k127_7691744_17 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000004619 164.0
PYH2_k127_7691744_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000001433 151.0
PYH2_k127_7691744_19 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000003034 134.0
PYH2_k127_7691744_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 576.0
PYH2_k127_7691744_20 CheW-like domain K02659 - - 0.0000000000000000000000000000003668 129.0
PYH2_k127_7691744_21 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000442 119.0
PYH2_k127_7691744_22 CRISPR_assoc - - - 0.00001269 55.0
PYH2_k127_7691744_3 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 544.0
PYH2_k127_7691744_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 521.0
PYH2_k127_7691744_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 474.0
PYH2_k127_7691744_6 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
PYH2_k127_7691744_7 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 367.0
PYH2_k127_7691744_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 317.0
PYH2_k127_7691744_9 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
PYH2_k127_7738717_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1015.0
PYH2_k127_7738717_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 4.332e-223 700.0
PYH2_k127_7738717_10 Transposase IS200 like K07491 - - 0.0000000000000000001464 89.0
PYH2_k127_7738717_11 Transposase IS200 like K07491 - - 0.0000000000000000009176 91.0
PYH2_k127_7738717_12 - - - - 0.000000000000121 76.0
PYH2_k127_7738717_13 Type II secretory pathway component PulF K02505,K12278 - - 0.00000000002045 64.0
PYH2_k127_7738717_14 DNA integration - - - 0.0000003439 52.0
PYH2_k127_7738717_2 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 601.0
PYH2_k127_7738717_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 475.0
PYH2_k127_7738717_4 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 476.0
PYH2_k127_7738717_5 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 398.0
PYH2_k127_7738717_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 383.0
PYH2_k127_7738717_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
PYH2_k127_7738717_8 HIUase/Transthyretin family K07127 - 3.5.2.17 0.000000000000000000000000000005114 124.0
PYH2_k127_7738717_9 Transposase IS200 like K07491 - - 0.00000000000000000007601 89.0
PYH2_k127_7746130_0 FAD dependent oxidoreductase central domain - - - 0.0 1227.0
PYH2_k127_7746130_1 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 536.0
PYH2_k127_7746130_2 PFAM ABC transporter related K02028,K09972,K10004 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000879 278.0
PYH2_k127_7752183_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 4.317e-234 734.0
PYH2_k127_7752183_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 528.0
PYH2_k127_7752183_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 444.0
PYH2_k127_7752183_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 433.0
PYH2_k127_7752183_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
PYH2_k127_7752183_5 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 321.0
PYH2_k127_7752183_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
PYH2_k127_7752183_7 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000206 269.0
PYH2_k127_7752183_8 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000918 171.0
PYH2_k127_7752183_9 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000961 71.0
PYH2_k127_7783219_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.782e-238 750.0
PYH2_k127_7783219_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 459.0
PYH2_k127_7783219_2 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 382.0
PYH2_k127_7783219_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 326.0
PYH2_k127_7783219_4 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 289.0
PYH2_k127_7783219_5 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000006771 211.0
PYH2_k127_7783219_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006685 179.0
PYH2_k127_7783219_7 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.000000000000000000000000000000000000000000004776 175.0
PYH2_k127_7783219_8 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000222 130.0
PYH2_k127_7824561_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 7.542e-243 758.0
PYH2_k127_7824561_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 592.0
PYH2_k127_7824561_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 477.0
PYH2_k127_7824561_4 Transcriptional regulator - - - 0.0000000000000000000000000000005068 126.0
PYH2_k127_7824561_5 - - - - 0.00000000000000000000000231 103.0
PYH2_k127_7824561_6 DsrE/DsrF-like family - - - 0.00000001443 63.0
PYH2_k127_7824561_7 Belongs to the 'phage' integrase family - - - 0.00000003128 55.0
PYH2_k127_7841740_0 amidohydrolase K01451 - 3.5.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 564.0
PYH2_k127_7841740_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 397.0
PYH2_k127_7841740_2 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001887 227.0
PYH2_k127_7841740_3 Sulfite exporter TauE/SafE - - - 0.0000000000284 66.0
PYH2_k127_7843228_0 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000005369 161.0
PYH2_k127_7843228_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000001592 154.0
PYH2_k127_7843228_2 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000000000000000000003264 158.0
PYH2_k127_7843228_3 Planctomycete cytochrome C - - - 0.0000000000000000000001162 103.0
PYH2_k127_7848414_0 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 309.0
PYH2_k127_7848414_1 PFAM Prokaryotic protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003375 262.0
PYH2_k127_7848414_2 amine dehydrogenase activity - - - 0.000000000000000000000001536 109.0
PYH2_k127_7894589_0 Prolyl oligopeptidase K01322 - 3.4.21.26 9.643e-225 715.0
PYH2_k127_7894589_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 549.0
PYH2_k127_7894589_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 419.0
PYH2_k127_7894589_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001137 226.0
PYH2_k127_7894589_4 - - - - 0.000000000000000000000000000000005649 135.0
PYH2_k127_7969340_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001864 233.0
PYH2_k127_7969340_1 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000000000000000002601 156.0
PYH2_k127_7984373_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1183.0
PYH2_k127_7984373_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 299.0
PYH2_k127_7984373_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000002993 169.0
PYH2_k127_7984373_3 PFAM cytoplasmic chaperone TorD family protein - - - 0.000000000000000000000000000000005405 141.0
PYH2_k127_8015889_0 cytosine deaminase K01485 - 3.5.4.1 3.06e-228 711.0
PYH2_k127_8015889_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 448.0
PYH2_k127_8015889_10 Protein of unknown function (DUF3144) - - - 0.00000002376 67.0
PYH2_k127_8015889_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 399.0
PYH2_k127_8015889_3 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 368.0
PYH2_k127_8015889_4 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 354.0
PYH2_k127_8015889_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
PYH2_k127_8015889_6 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 291.0
PYH2_k127_8015889_7 - - - - 0.000000000000000000000000000000000000000000000000000000003016 208.0
PYH2_k127_8015889_8 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000002007 151.0
PYH2_k127_8015889_9 BON domain - - - 0.00000000000000000000000000000000000034 156.0
PYH2_k127_8023357_0 AMP-binding enzyme K12508 - 6.2.1.34 2.303e-246 774.0
PYH2_k127_8023357_1 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 515.0
PYH2_k127_8023357_2 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 511.0
PYH2_k127_8023357_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 471.0
PYH2_k127_8023357_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 401.0
PYH2_k127_8023357_5 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000002848 197.0
PYH2_k127_8023357_6 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000003569 187.0
PYH2_k127_8023357_7 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000001046 183.0
PYH2_k127_8023357_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.00000000001141 65.0
PYH2_k127_8025351_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 507.0
PYH2_k127_8025351_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 467.0
PYH2_k127_8025351_11 Post-segregation antitoxin CcdA K19164 - - 0.00000000000000000192 90.0
PYH2_k127_8025351_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 394.0
PYH2_k127_8025351_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
PYH2_k127_8025351_4 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 316.0
PYH2_k127_8025351_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006412 282.0
PYH2_k127_8025351_6 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000125 252.0
PYH2_k127_8025351_7 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000001764 220.0
PYH2_k127_8025351_8 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000379 201.0
PYH2_k127_8025351_9 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000001896 175.0
PYH2_k127_8055824_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 340.0
PYH2_k127_8055824_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003404 250.0
PYH2_k127_8090120_0 Tetratricopeptide repeat - - - 1.571e-234 742.0
PYH2_k127_8090120_1 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 2.2e-228 716.0
PYH2_k127_8090120_2 Tetratricopeptide repeat - - - 9.326e-219 696.0
PYH2_k127_8090120_3 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 500.0
PYH2_k127_8090120_4 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 355.0
PYH2_k127_8090120_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 290.0
PYH2_k127_8090120_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001314 277.0
PYH2_k127_8090120_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
PYH2_k127_8090120_8 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000531 257.0
PYH2_k127_8092043_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1216.0
PYH2_k127_8092043_1 D-amino acid K00285 - 1.4.5.1 1.734e-210 659.0
PYH2_k127_8092043_10 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 406.0
PYH2_k127_8092043_11 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
PYH2_k127_8092043_12 binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 370.0
PYH2_k127_8092043_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 328.0
PYH2_k127_8092043_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000009055 261.0
PYH2_k127_8092043_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
PYH2_k127_8092043_17 COG0112 Glycine serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000001848 168.0
PYH2_k127_8092043_18 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000006798 72.0
PYH2_k127_8092043_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 614.0
PYH2_k127_8092043_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 580.0
PYH2_k127_8092043_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 572.0
PYH2_k127_8092043_5 PFAM extracellular solute-binding protein family 1 K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 528.0
PYH2_k127_8092043_6 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 481.0
PYH2_k127_8092043_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 470.0
PYH2_k127_8092043_8 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 457.0
PYH2_k127_8092043_9 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 431.0
PYH2_k127_8134713_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 6.19e-243 771.0
PYH2_k127_8134713_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 473.0
PYH2_k127_8134713_2 Decaheme c-type cytochrome, DmsE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 430.0
PYH2_k127_8134713_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 364.0
PYH2_k127_8134713_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
PYH2_k127_8134713_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000001242 227.0
PYH2_k127_8134713_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000001104 50.0
PYH2_k127_8136921_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1274.0
PYH2_k127_8136921_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 595.0
PYH2_k127_8136921_10 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000002158 236.0
PYH2_k127_8136921_11 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000007504 191.0
PYH2_k127_8136921_12 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000003273 152.0
PYH2_k127_8136921_13 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000361 95.0
PYH2_k127_8136921_14 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000001073 57.0
PYH2_k127_8136921_16 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000004319 50.0
PYH2_k127_8136921_17 family) member 1 - - - 0.0003889 48.0
PYH2_k127_8136921_2 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 545.0
PYH2_k127_8136921_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
PYH2_k127_8136921_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 429.0
PYH2_k127_8136921_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 415.0
PYH2_k127_8136921_6 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
PYH2_k127_8136921_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 402.0
PYH2_k127_8136921_8 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009871 258.0
PYH2_k127_8136921_9 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001255 250.0
PYH2_k127_8262215_0 SNARE associated Golgi protein - - - 2.708e-317 987.0
PYH2_k127_8262215_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
PYH2_k127_8262215_2 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 321.0
PYH2_k127_8262215_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005388 256.0
PYH2_k127_8262215_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
PYH2_k127_8262215_5 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000003047 140.0
PYH2_k127_8262215_6 Putative zinc-finger - - - 0.00001003 51.0
PYH2_k127_8262215_7 Glycosyltransferase like family 2 - - - 0.0004132 43.0
PYH2_k127_8281142_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.302e-304 938.0
PYH2_k127_8281142_1 PrkA AAA domain K07180 - - 8.929e-275 859.0
PYH2_k127_8281142_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 508.0
PYH2_k127_8281142_11 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 477.0
PYH2_k127_8281142_12 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 463.0
PYH2_k127_8281142_13 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
PYH2_k127_8281142_14 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 426.0
PYH2_k127_8281142_15 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 422.0
PYH2_k127_8281142_16 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 414.0
PYH2_k127_8281142_17 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 422.0
PYH2_k127_8281142_18 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 404.0
PYH2_k127_8281142_19 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 407.0
PYH2_k127_8281142_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.716e-256 810.0
PYH2_k127_8281142_20 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
PYH2_k127_8281142_21 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 388.0
PYH2_k127_8281142_22 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 402.0
PYH2_k127_8281142_23 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
PYH2_k127_8281142_24 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
PYH2_k127_8281142_25 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
PYH2_k127_8281142_26 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 321.0
PYH2_k127_8281142_27 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 314.0
PYH2_k127_8281142_28 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 299.0
PYH2_k127_8281142_29 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 284.0
PYH2_k127_8281142_3 Peptidase family S49 K04773 - - 7.421e-216 687.0
PYH2_k127_8281142_30 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
PYH2_k127_8281142_31 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
PYH2_k127_8281142_32 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH2_k127_8281142_33 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002569 271.0
PYH2_k127_8281142_34 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000001709 248.0
PYH2_k127_8281142_35 cytochrome C oxidase K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
PYH2_k127_8281142_36 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000006028 251.0
PYH2_k127_8281142_37 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000002866 240.0
PYH2_k127_8281142_38 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
PYH2_k127_8281142_39 Hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000521 228.0
PYH2_k127_8281142_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.806e-211 665.0
PYH2_k127_8281142_40 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001489 225.0
PYH2_k127_8281142_41 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
PYH2_k127_8281142_42 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000005632 224.0
PYH2_k127_8281142_43 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
PYH2_k127_8281142_44 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000221 212.0
PYH2_k127_8281142_45 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000001276 194.0
PYH2_k127_8281142_46 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000001101 186.0
PYH2_k127_8281142_47 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000002118 196.0
PYH2_k127_8281142_48 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000007444 175.0
PYH2_k127_8281142_49 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000002451 178.0
PYH2_k127_8281142_5 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 563.0
PYH2_k127_8281142_50 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000002494 176.0
PYH2_k127_8281142_51 Lysin motif - - - 0.000000000000000000000000000000000000000000005261 165.0
PYH2_k127_8281142_52 Type II secretory pathway, component - - - 0.00000000000000000000000000000000000000000108 167.0
PYH2_k127_8281142_53 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000004252 167.0
PYH2_k127_8281142_54 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000009081 152.0
PYH2_k127_8281142_55 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000746 141.0
PYH2_k127_8281142_56 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000004231 145.0
PYH2_k127_8281142_57 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000002025 136.0
PYH2_k127_8281142_58 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000007155 134.0
PYH2_k127_8281142_59 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000001775 111.0
PYH2_k127_8281142_6 SpoVR family K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 556.0
PYH2_k127_8281142_60 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000000006442 104.0
PYH2_k127_8281142_61 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000008934 97.0
PYH2_k127_8281142_62 Protein of unknown function (DUF2970) - - - 0.000000000000000001085 91.0
PYH2_k127_8281142_63 Protein of unknown function (DUF2909) - - - 0.00000000000001726 75.0
PYH2_k127_8281142_64 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000003772 68.0
PYH2_k127_8281142_65 mercury ion transmembrane transporter activity - - - 0.0000000008497 64.0
PYH2_k127_8281142_67 - - - - 0.0002845 51.0
PYH2_k127_8281142_68 Lysin motif - - - 0.000695 46.0
PYH2_k127_8281142_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 547.0
PYH2_k127_8281142_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 518.0
PYH2_k127_8281142_9 Cobalamin biosynthesis protein CobW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 511.0
PYH2_k127_8287226_0 4Fe-4S dicluster domain K18930 - - 0.0 1143.0
PYH2_k127_8287226_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1059.0
PYH2_k127_8287226_10 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 323.0
PYH2_k127_8287226_11 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001426 274.0
PYH2_k127_8287226_12 Protein of unknown function, DUF480 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 264.0
PYH2_k127_8287226_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000002086 205.0
PYH2_k127_8287226_14 PIN domain - - - 0.00000000000000000000000000000000000000000009692 162.0
PYH2_k127_8287226_15 CBS domain - - - 0.0000000000000000000000000000008658 132.0
PYH2_k127_8287226_16 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000002446 118.0
PYH2_k127_8287226_17 Histidine kinase - - - 0.0000000000000000000000000418 115.0
PYH2_k127_8287226_18 - - - - 0.00000000000000000236 89.0
PYH2_k127_8287226_19 mRNA binding K07339 - - 0.00000000000000002099 81.0
PYH2_k127_8287226_2 GGDEF domain - - - 1.449e-311 976.0
PYH2_k127_8287226_20 positive regulation of growth - - - 0.00000000000002105 75.0
PYH2_k127_8287226_3 GGDEF domain - - - 2.039e-286 904.0
PYH2_k127_8287226_4 Subtilase family - - - 5.772e-258 816.0
PYH2_k127_8287226_5 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.543e-233 734.0
PYH2_k127_8287226_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 533.0
PYH2_k127_8287226_7 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 473.0
PYH2_k127_8287226_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 430.0
PYH2_k127_8287226_9 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 312.0
PYH2_k127_8341373_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1160.0
PYH2_k127_8341373_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 310.0
PYH2_k127_8411011_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1398.0
PYH2_k127_8411011_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1382.0
PYH2_k127_8411011_10 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000223 166.0
PYH2_k127_8411011_11 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000001983 121.0
PYH2_k127_8411011_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 5.681e-306 949.0
PYH2_k127_8411011_3 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 2.447e-286 891.0
PYH2_k127_8411011_4 CoA-transferase family III - - - 2.583e-210 665.0
PYH2_k127_8411011_5 COG1960 Acyl-CoA dehydrogenases - - - 4.412e-199 625.0
PYH2_k127_8411011_6 branched-chain amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 477.0
PYH2_k127_8411011_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 425.0
PYH2_k127_8411011_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 299.0
PYH2_k127_8411011_9 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000001344 213.0
PYH2_k127_8438280_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.369e-302 940.0
PYH2_k127_8438280_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.104e-247 765.0
PYH2_k127_8438280_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000007377 165.0
PYH2_k127_8438280_3 membrane - - - 0.000000000000000000000000000000000704 132.0
PYH2_k127_8438280_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000775 125.0
PYH2_k127_8438280_5 - - - - 0.0000000000000002878 83.0
PYH2_k127_8438280_6 - - - - 0.000000003413 61.0
PYH2_k127_8439283_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 521.0
PYH2_k127_8439283_1 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 453.0
PYH2_k127_8439283_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 335.0
PYH2_k127_8439465_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 5.923e-267 834.0
PYH2_k127_8439465_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.909e-240 752.0
PYH2_k127_8439465_2 Aldehyde dehydrogenase family K15514 - 1.2.1.77 3.538e-215 679.0
PYH2_k127_8439465_3 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 525.0
PYH2_k127_8439465_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 374.0
PYH2_k127_8439465_5 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003884 231.0
PYH2_k127_8439465_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000008549 114.0
PYH2_k127_8439465_7 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000119 91.0
PYH2_k127_8464624_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
PYH2_k127_8464624_1 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000003735 196.0
PYH2_k127_8464624_2 toxin-antitoxin pair type II binding - - - 0.0000000000000000003021 89.0
PYH2_k127_8469977_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1008.0
PYH2_k127_8469977_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 514.0
PYH2_k127_8469977_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 452.0
PYH2_k127_8469977_3 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 429.0
PYH2_k127_8469977_4 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 425.0
PYH2_k127_8469977_5 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
PYH2_k127_8469977_6 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
PYH2_k127_8469977_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
PYH2_k127_8469977_8 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 320.0
PYH2_k127_8469977_9 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000001999 142.0
PYH2_k127_8479612_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 295.0
PYH2_k127_8479612_1 NHL repeat - - - 0.000000000000000000000000000000000000000008357 158.0
PYH2_k127_8479612_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000001636 145.0
PYH2_k127_8479612_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000002545 113.0
PYH2_k127_8481493_0 Ketopantoate hydroxymethyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 497.0
PYH2_k127_8481493_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 377.0
PYH2_k127_8481493_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 354.0
PYH2_k127_8481493_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 266.0
PYH2_k127_8481493_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000003384 239.0
PYH2_k127_8481493_5 COG1145 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000004916 214.0
PYH2_k127_8481493_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - GO:0003674,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008270,GO:0015711,GO:0015718,GO:0015727,GO:0015849,GO:0015850,GO:0031317,GO:0032991,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046942,GO:0046983,GO:0051179,GO:0051234,GO:0071702,GO:1990351 - 0.0000000000000000000000000000000000000000000001964 177.0
PYH2_k127_8487912_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1347.0
PYH2_k127_8487912_1 Belongs to the transketolase family K00615 - 2.2.1.1 1.437e-289 906.0
PYH2_k127_8487912_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 467.0
PYH2_k127_8487912_11 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 431.0
PYH2_k127_8487912_12 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 405.0
PYH2_k127_8487912_13 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 371.0
PYH2_k127_8487912_14 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 347.0
PYH2_k127_8487912_15 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 298.0
PYH2_k127_8487912_16 FHA Domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 293.0
PYH2_k127_8487912_17 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000005509 209.0
PYH2_k127_8487912_18 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000009946 212.0
PYH2_k127_8487912_19 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000005222 207.0
PYH2_k127_8487912_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 5.035e-283 880.0
PYH2_k127_8487912_20 ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000000000000000001837 151.0
PYH2_k127_8487912_21 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000002651 153.0
PYH2_k127_8487912_22 Lysin motif - - - 0.000000000000000000000000000000001811 140.0
PYH2_k127_8487912_23 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000001171 119.0
PYH2_k127_8487912_24 Barstar (barnase inhibitor) - - - 0.0000000000000000000003212 100.0
PYH2_k127_8487912_25 Histidine kinase-like ATPase domain - - - 0.000000000000000000006643 98.0
PYH2_k127_8487912_26 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.0000000000000005129 81.0
PYH2_k127_8487912_28 - - - - 0.0000002273 58.0
PYH2_k127_8487912_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.909e-231 730.0
PYH2_k127_8487912_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.42e-214 676.0
PYH2_k127_8487912_5 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
PYH2_k127_8487912_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 593.0
PYH2_k127_8487912_7 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 582.0
PYH2_k127_8487912_8 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 548.0
PYH2_k127_8487912_9 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 556.0
PYH2_k127_8504040_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 587.0
PYH2_k127_8504040_1 Spermidine putrescine-binding periplasmic protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 587.0
PYH2_k127_8504040_2 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 483.0
PYH2_k127_8504040_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 474.0
PYH2_k127_8504040_4 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 449.0
PYH2_k127_8504040_5 Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 420.0
PYH2_k127_8504040_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 367.0
PYH2_k127_8504040_7 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 334.0
PYH2_k127_8504040_8 - - - - 0.0000000000000000000000000000000000000005495 150.0
PYH2_k127_8506043_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 1.391e-229 733.0
PYH2_k127_8506043_1 L-carnitine dehydratase bile acid-inducible protein F - - - 7.847e-203 637.0
PYH2_k127_8506043_10 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000005718 89.0
PYH2_k127_8506043_11 - - - - 0.000000002124 62.0
PYH2_k127_8506043_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.173e-195 621.0
PYH2_k127_8506043_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 543.0
PYH2_k127_8506043_4 Multidrug ABC transporter permease K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 471.0
PYH2_k127_8506043_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 433.0
PYH2_k127_8506043_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 384.0
PYH2_k127_8506043_7 PFAM conserved K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 340.0
PYH2_k127_8506043_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 317.0
PYH2_k127_8506043_9 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000002325 100.0
PYH2_k127_8520331_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 606.0
PYH2_k127_8520331_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 574.0
PYH2_k127_8520331_10 Phage integrase family - - - 0.00002662 48.0
PYH2_k127_8520331_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 459.0
PYH2_k127_8520331_3 MMPL family K03296,K18138,K18902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 381.0
PYH2_k127_8520331_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 351.0
PYH2_k127_8520331_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 300.0
PYH2_k127_8520331_6 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001556 239.0
PYH2_k127_8520331_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001069 220.0
PYH2_k127_8520331_8 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000001702 185.0
PYH2_k127_8520331_9 Fatty acid hydroxylase superfamily - - - 0.000000001455 62.0
PYH2_k127_8522930_0 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 346.0
PYH2_k127_8522930_1 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000000007959 196.0
PYH2_k127_8538672_0 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 304.0
PYH2_k127_8538672_1 mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000002184 223.0
PYH2_k127_8538672_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000005651 200.0
PYH2_k127_8543669_0 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 304.0
PYH2_k127_8543669_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000006728 123.0
PYH2_k127_8543669_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000006648 109.0
PYH2_k127_8543669_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000005872 107.0
PYH2_k127_8574097_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1217.0
PYH2_k127_8574097_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 563.0
PYH2_k127_8574097_10 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 357.0
PYH2_k127_8574097_11 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 359.0
PYH2_k127_8574097_12 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 349.0
PYH2_k127_8574097_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 348.0
PYH2_k127_8574097_14 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 299.0
PYH2_k127_8574097_15 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 299.0
PYH2_k127_8574097_16 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000107 268.0
PYH2_k127_8574097_17 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
PYH2_k127_8574097_18 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000236 204.0
PYH2_k127_8574097_19 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000005823 198.0
PYH2_k127_8574097_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 519.0
PYH2_k127_8574097_20 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000001235 193.0
PYH2_k127_8574097_21 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000000228 195.0
PYH2_k127_8574097_22 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000001447 156.0
PYH2_k127_8574097_23 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000005685 154.0
PYH2_k127_8574097_24 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000004119 157.0
PYH2_k127_8574097_25 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000002299 118.0
PYH2_k127_8574097_26 diguanylate cyclase - - - 0.00000000000000005215 89.0
PYH2_k127_8574097_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 519.0
PYH2_k127_8574097_4 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 494.0
PYH2_k127_8574097_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 489.0
PYH2_k127_8574097_6 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 477.0
PYH2_k127_8574097_7 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 457.0
PYH2_k127_8574097_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 454.0
PYH2_k127_8574097_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 436.0
PYH2_k127_8599022_0 Belongs to the peptidase M16 family K07263 - - 1.462e-281 885.0
PYH2_k127_8599022_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 372.0
PYH2_k127_8599022_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000248 232.0
PYH2_k127_8599022_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000001669 171.0
PYH2_k127_8599022_12 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000002477 171.0
PYH2_k127_8599022_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000018 171.0
PYH2_k127_8599022_14 - - - - 0.00000000000000000000000000000000258 131.0
PYH2_k127_8599022_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000004115 67.0
PYH2_k127_8599022_16 Domain of unknown function (DUF4936) - - - 0.0000002636 56.0
PYH2_k127_8599022_17 - - - - 0.0004828 44.0
PYH2_k127_8599022_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 335.0
PYH2_k127_8599022_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 323.0
PYH2_k127_8599022_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 271.0
PYH2_k127_8599022_5 dna polymerase iii K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000009239 258.0
PYH2_k127_8599022_6 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006825 247.0
PYH2_k127_8599022_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
PYH2_k127_8599022_8 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003794 249.0
PYH2_k127_8599022_9 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
PYH2_k127_8613145_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1020.0
PYH2_k127_8613145_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1019.0
PYH2_k127_8613145_10 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 525.0
PYH2_k127_8613145_11 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 537.0
PYH2_k127_8613145_12 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 517.0
PYH2_k127_8613145_13 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 496.0
PYH2_k127_8613145_14 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 483.0
PYH2_k127_8613145_15 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 475.0
PYH2_k127_8613145_16 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
PYH2_k127_8613145_17 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 444.0
PYH2_k127_8613145_18 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 436.0
PYH2_k127_8613145_19 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 420.0
PYH2_k127_8613145_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1015.0
PYH2_k127_8613145_20 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 418.0
PYH2_k127_8613145_21 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 412.0
PYH2_k127_8613145_22 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
PYH2_k127_8613145_23 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 357.0
PYH2_k127_8613145_24 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
PYH2_k127_8613145_25 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 288.0
PYH2_k127_8613145_26 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005505 290.0
PYH2_k127_8613145_27 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001189 287.0
PYH2_k127_8613145_28 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000278 265.0
PYH2_k127_8613145_29 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 256.0
PYH2_k127_8613145_3 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 3.854e-288 917.0
PYH2_k127_8613145_30 lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005381 253.0
PYH2_k127_8613145_31 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000002599 244.0
PYH2_k127_8613145_32 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
PYH2_k127_8613145_33 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008236 242.0
PYH2_k127_8613145_34 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
PYH2_k127_8613145_35 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
PYH2_k127_8613145_36 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000000002238 195.0
PYH2_k127_8613145_37 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001242 201.0
PYH2_k127_8613145_38 DUF218 domain - - - 0.00000000000000000000000000000000000000000000001783 181.0
PYH2_k127_8613145_39 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000001277 171.0
PYH2_k127_8613145_4 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 1.607e-277 864.0
PYH2_k127_8613145_40 NLP P60 protein - - - 0.0000000000000000000000000000000000000002734 158.0
PYH2_k127_8613145_41 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000002889 156.0
PYH2_k127_8613145_42 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000002406 153.0
PYH2_k127_8613145_43 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000003381 145.0
PYH2_k127_8613145_44 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000009058 143.0
PYH2_k127_8613145_45 membrane - - - 0.0000000000000000000000000000000000008998 150.0
PYH2_k127_8613145_46 Transposase K07499 - - 0.00000000000000000000000000002563 123.0
PYH2_k127_8613145_47 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000546 113.0
PYH2_k127_8613145_48 TM2 domain - - - 0.000000000000000000003841 97.0
PYH2_k127_8613145_49 - - - - 0.000000000000000000008952 98.0
PYH2_k127_8613145_5 PFAM AMP-dependent synthetase and ligase K00666 - - 5.726e-271 842.0
PYH2_k127_8613145_50 DDE superfamily endonuclease K07494 - - 0.0000000000009891 71.0
PYH2_k127_8613145_51 Protein conserved in bacteria K09705 - - 0.000000003839 64.0
PYH2_k127_8613145_52 DDE superfamily endonuclease - - - 0.000007176 55.0
PYH2_k127_8613145_54 RDD family - - - 0.00005287 50.0
PYH2_k127_8613145_6 Cysteine-rich domain - - - 5.65e-212 666.0
PYH2_k127_8613145_7 Oxidoreductase - - - 1.522e-205 651.0
PYH2_k127_8613145_8 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 620.0
PYH2_k127_8613145_9 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 546.0
PYH2_k127_8619861_0 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 437.0
PYH2_k127_8619861_1 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 392.0
PYH2_k127_8619861_10 PFAM Major facilitator superfamily K02575 - - 0.00000000000000001185 87.0
PYH2_k127_8619861_2 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 372.0
PYH2_k127_8619861_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 314.0
PYH2_k127_8619861_4 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 297.0
PYH2_k127_8619861_5 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
PYH2_k127_8619861_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
PYH2_k127_8619861_7 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
PYH2_k127_8619861_8 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006918 171.0
PYH2_k127_8619861_9 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000002096 108.0
PYH2_k127_8623987_0 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 351.0
PYH2_k127_8623987_1 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 293.0
PYH2_k127_8623987_10 SnoaL-like polyketide cyclase - - - 0.00000007044 56.0
PYH2_k127_8623987_11 Acetyltransferase (GNAT) domain - - - 0.0002177 44.0
PYH2_k127_8623987_12 Protein of unknown function (DUF2934) - - - 0.0003671 48.0
PYH2_k127_8623987_13 - - - - 0.0004605 44.0
PYH2_k127_8623987_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14583,K14751 - 1.13.11.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 292.0
PYH2_k127_8623987_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001453 270.0
PYH2_k127_8623987_4 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004349 264.0
PYH2_k127_8623987_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000001106 220.0
PYH2_k127_8623987_6 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000007547 214.0
PYH2_k127_8623987_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000059 138.0
PYH2_k127_8623987_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000265 97.0
PYH2_k127_8623987_9 Phosphotransferase System K11189 - - 0.0000000000000001933 83.0
PYH2_k127_8663086_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.53e-282 874.0
PYH2_k127_8663086_1 Chromate K07240 - - 1.118e-205 649.0
PYH2_k127_8663086_10 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000001374 82.0
PYH2_k127_8663086_11 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000001045 74.0
PYH2_k127_8663086_12 - - - - 0.0000000001824 64.0
PYH2_k127_8663086_13 Acetyltransferase (GNAT) domain - - - 0.000000003221 64.0
PYH2_k127_8663086_14 Acetyltransferase (GNAT) domain - - - 0.0004646 47.0
PYH2_k127_8663086_2 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 584.0
PYH2_k127_8663086_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 542.0
PYH2_k127_8663086_4 Superoxide dismutase K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 344.0
PYH2_k127_8663086_5 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 304.0
PYH2_k127_8663086_6 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003171 282.0
PYH2_k127_8663086_7 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000008695 236.0
PYH2_k127_8663086_8 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000006172 207.0
PYH2_k127_8663086_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000009803 183.0
PYH2_k127_8692522_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.441e-314 969.0
PYH2_k127_8692522_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.043e-219 697.0
PYH2_k127_8692522_10 import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000295 181.0
PYH2_k127_8692522_11 - - - - 0.0000000000000000000000000000000005089 143.0
PYH2_k127_8692522_12 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000003634 137.0
PYH2_k127_8692522_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 572.0
PYH2_k127_8692522_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 498.0
PYH2_k127_8692522_4 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 472.0
PYH2_k127_8692522_5 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
PYH2_k127_8692522_6 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 392.0
PYH2_k127_8692522_7 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 369.0
PYH2_k127_8692522_8 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
PYH2_k127_8692522_9 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000005533 188.0
PYH2_k127_8705885_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 561.0
PYH2_k127_8705885_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 361.0
PYH2_k127_8705885_2 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000005938 194.0
PYH2_k127_8708833_0 PIN domain - - - 0.000000000000000000000000000008576 126.0
PYH2_k127_8708833_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000001332 94.0
PYH2_k127_8713609_0 Sulfate transporter antisigma-factor antagonist STAS - - - 7.14e-274 848.0
PYH2_k127_8713609_1 AI-2E family transporter - - - 0.000000000001252 69.0
PYH2_k127_8723403_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 473.0
PYH2_k127_8723403_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000001055 219.0
PYH2_k127_8723403_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004713 216.0
PYH2_k127_8723403_3 Gram-negative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000005006 204.0
PYH2_k127_8729881_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.345e-261 819.0
PYH2_k127_8729881_1 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.342e-203 641.0
PYH2_k127_8729881_2 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 535.0
PYH2_k127_8729881_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 374.0
PYH2_k127_8729881_4 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
PYH2_k127_8729881_5 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000002451 216.0
PYH2_k127_8729881_6 PAC sensor-containing diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000402 190.0
PYH2_k127_8729881_7 Belongs to the pirin family K06911 - - 0.000000000000000001259 85.0
PYH2_k127_8731269_0 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000000000000000001386 209.0
PYH2_k127_8731269_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000003192 139.0
PYH2_k127_8731269_2 Transposase IS4 family - - - 0.00000004586 59.0
PYH2_k127_8731269_3 Abortive infection C-terminus - - - 0.000001603 56.0
PYH2_k127_8731269_4 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.0003079 53.0
PYH2_k127_8851172_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001049 276.0
PYH2_k127_8851172_1 Major facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000001248 215.0
PYH2_k127_8851172_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.00000277 58.0
PYH2_k127_8863185_0 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.0000000000000000000000000000000000000002466 160.0
PYH2_k127_8863185_1 ORF6N domain - - - 0.00000000000000000000000000000000000437 142.0
PYH2_k127_8863185_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000704 132.0
PYH2_k127_8863185_3 PFAM PIN domain - - - 0.000000000000000000000000005969 114.0
PYH2_k127_8863185_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000002628 55.0
PYH2_k127_8928438_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1693.0
PYH2_k127_8928438_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.804e-247 785.0
PYH2_k127_8928438_10 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
PYH2_k127_8928438_11 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
PYH2_k127_8928438_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
PYH2_k127_8928438_13 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 353.0
PYH2_k127_8928438_14 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 332.0
PYH2_k127_8928438_15 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 316.0
PYH2_k127_8928438_16 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 312.0
PYH2_k127_8928438_17 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
PYH2_k127_8928438_18 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000005466 244.0
PYH2_k127_8928438_19 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
PYH2_k127_8928438_2 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 1.043e-223 703.0
PYH2_k127_8928438_20 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000004554 202.0
PYH2_k127_8928438_21 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000002885 165.0
PYH2_k127_8928438_22 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000005213 166.0
PYH2_k127_8928438_23 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000174 149.0
PYH2_k127_8928438_24 Adenylate cyclase - - - 0.000000000000000000000000000000000000401 148.0
PYH2_k127_8928438_25 TIGRFAM phasin family protein - - - 0.00000000000000000000000000000000001019 143.0
PYH2_k127_8928438_26 - - - - 0.0000000000000000000007265 104.0
PYH2_k127_8928438_27 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000007405 101.0
PYH2_k127_8928438_3 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 602.0
PYH2_k127_8928438_4 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 602.0
PYH2_k127_8928438_5 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 462.0
PYH2_k127_8928438_6 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 425.0
PYH2_k127_8928438_7 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
PYH2_k127_8928438_8 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 397.0
PYH2_k127_8928438_9 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 382.0
PYH2_k127_8938694_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1741.0
PYH2_k127_8938694_1 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 611.0
PYH2_k127_8938694_2 5-oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 533.0
PYH2_k127_8938694_3 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
PYH2_k127_8938694_4 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 297.0
PYH2_k127_8938694_5 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002721 279.0
PYH2_k127_8938694_6 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002262 247.0
PYH2_k127_8938694_7 - - - - 0.000000000000000000000000000003694 126.0
PYH2_k127_8938694_8 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000049 110.0
PYH2_k127_9029333_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 419.0
PYH2_k127_9029333_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000004884 92.0
PYH2_k127_9029333_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000003286 84.0
PYH2_k127_9057970_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 999.0
PYH2_k127_9057970_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.6e-259 805.0
PYH2_k127_9057970_10 negative regulator of sigma E activity K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007043 272.0
PYH2_k127_9057970_11 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009977 258.0
PYH2_k127_9057970_12 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000005198 248.0
PYH2_k127_9057970_13 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
PYH2_k127_9057970_14 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
PYH2_k127_9057970_15 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000001299 156.0
PYH2_k127_9057970_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000003012 132.0
PYH2_k127_9057970_17 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000005035 112.0
PYH2_k127_9057970_18 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000001078 89.0
PYH2_k127_9057970_19 Anti sigma-E protein RseA K03597 - - 0.0000000003012 68.0
PYH2_k127_9057970_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.665e-210 659.0
PYH2_k127_9057970_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 557.0
PYH2_k127_9057970_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 447.0
PYH2_k127_9057970_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 447.0
PYH2_k127_9057970_6 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
PYH2_k127_9057970_7 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 380.0
PYH2_k127_9057970_8 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 341.0
PYH2_k127_9057970_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 309.0
PYH2_k127_9075622_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1392.0
PYH2_k127_9075622_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1175.0
PYH2_k127_9075622_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
PYH2_k127_9075622_11 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 566.0
PYH2_k127_9075622_12 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 565.0
PYH2_k127_9075622_13 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 548.0
PYH2_k127_9075622_14 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 524.0
PYH2_k127_9075622_15 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 491.0
PYH2_k127_9075622_16 protein conserved in bacteria K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 527.0
PYH2_k127_9075622_17 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
PYH2_k127_9075622_18 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 432.0
PYH2_k127_9075622_19 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 426.0
PYH2_k127_9075622_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.723e-291 914.0
PYH2_k127_9075622_20 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 413.0
PYH2_k127_9075622_21 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 387.0
PYH2_k127_9075622_22 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
PYH2_k127_9075622_23 RNA polymerase sigma factor RpoS K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 338.0
PYH2_k127_9075622_24 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 327.0
PYH2_k127_9075622_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 317.0
PYH2_k127_9075622_26 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005932 280.0
PYH2_k127_9075622_27 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001275 261.0
PYH2_k127_9075622_28 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
PYH2_k127_9075622_29 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000006125 250.0
PYH2_k127_9075622_3 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 3.883e-243 761.0
PYH2_k127_9075622_30 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002433 241.0
PYH2_k127_9075622_31 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000003772 235.0
PYH2_k127_9075622_32 Tetratricopeptide repeat K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000004207 238.0
PYH2_k127_9075622_33 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000002016 233.0
PYH2_k127_9075622_34 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
PYH2_k127_9075622_35 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
PYH2_k127_9075622_36 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001893 229.0
PYH2_k127_9075622_37 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
PYH2_k127_9075622_38 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000005638 203.0
PYH2_k127_9075622_39 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000003049 193.0
PYH2_k127_9075622_4 Aminotransferase K14261 - - 4.698e-227 707.0
PYH2_k127_9075622_40 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000004759 185.0
PYH2_k127_9075622_41 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000004424 184.0
PYH2_k127_9075622_42 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000002057 160.0
PYH2_k127_9075622_43 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000003411 158.0
PYH2_k127_9075622_44 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000001806 147.0
PYH2_k127_9075622_45 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000004239 142.0
PYH2_k127_9075622_46 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000005623 126.0
PYH2_k127_9075622_47 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000000000001475 107.0
PYH2_k127_9075622_48 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000003143 93.0
PYH2_k127_9075622_49 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000001276 87.0
PYH2_k127_9075622_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.546e-219 687.0
PYH2_k127_9075622_50 protein conserved in bacteria K09937 - - 0.00000000000009749 74.0
PYH2_k127_9075622_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.9e-215 674.0
PYH2_k127_9075622_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.557e-199 629.0
PYH2_k127_9075622_8 Threonine synthase K01733 - 4.2.3.1 2.908e-197 625.0
PYH2_k127_9075622_9 homoserine dehydrogenase K00003 - 1.1.1.3 6.425e-197 623.0
PYH2_k127_9157508_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 379.0
PYH2_k127_9157508_1 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
PYH2_k127_9157508_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 291.0
PYH2_k127_9157508_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007162 269.0
PYH2_k127_9172301_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5.641e-289 908.0
PYH2_k127_9172301_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.518e-231 730.0
PYH2_k127_9172301_10 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 440.0
PYH2_k127_9172301_11 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 430.0
PYH2_k127_9172301_12 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 387.0
PYH2_k127_9172301_13 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 368.0
PYH2_k127_9172301_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
PYH2_k127_9172301_15 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
PYH2_k127_9172301_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 333.0
PYH2_k127_9172301_17 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 305.0
PYH2_k127_9172301_18 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 293.0
PYH2_k127_9172301_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
PYH2_k127_9172301_2 type IV pilus secretin PilQ K02666 - - 1.108e-230 739.0
PYH2_k127_9172301_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
PYH2_k127_9172301_21 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
PYH2_k127_9172301_22 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
PYH2_k127_9172301_23 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005549 244.0
PYH2_k127_9172301_24 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000007582 230.0
PYH2_k127_9172301_25 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
PYH2_k127_9172301_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
PYH2_k127_9172301_27 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003222 224.0
PYH2_k127_9172301_28 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
PYH2_k127_9172301_29 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000003528 213.0
PYH2_k127_9172301_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 540.0
PYH2_k127_9172301_30 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000001489 208.0
PYH2_k127_9172301_31 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000002003 198.0
PYH2_k127_9172301_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000001357 192.0
PYH2_k127_9172301_33 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000002329 191.0
PYH2_k127_9172301_34 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000005056 197.0
PYH2_k127_9172301_35 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000004068 177.0
PYH2_k127_9172301_36 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000007431 169.0
PYH2_k127_9172301_37 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001503 166.0
PYH2_k127_9172301_38 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000007947 167.0
PYH2_k127_9172301_39 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000001482 166.0
PYH2_k127_9172301_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 526.0
PYH2_k127_9172301_40 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003194 150.0
PYH2_k127_9172301_41 Redoxin domain protein - - - 0.000000000000000000000000000000000000001623 153.0
PYH2_k127_9172301_42 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000006185 147.0
PYH2_k127_9172301_43 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000004856 145.0
PYH2_k127_9172301_44 S4 RNA-binding domain - - - 0.0000000000000000000000000000000000009591 144.0
PYH2_k127_9172301_45 Belongs to the frataxin family K06202 - - 0.0000000000000000000000000000000004626 133.0
PYH2_k127_9172301_46 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000008779 131.0
PYH2_k127_9172301_47 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000006508 130.0
PYH2_k127_9172301_48 Large extracellular alpha-helical protein - - - 0.00000000000000000003073 106.0
PYH2_k127_9172301_49 Ribosomal protein L30 K02907 - - 0.00000000000000000009195 90.0
PYH2_k127_9172301_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 527.0
PYH2_k127_9172301_50 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000001755 83.0
PYH2_k127_9172301_51 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002176 73.0
PYH2_k127_9172301_52 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002828 72.0
PYH2_k127_9172301_6 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
PYH2_k127_9172301_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
PYH2_k127_9172301_8 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 456.0
PYH2_k127_9172301_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 453.0
PYH2_k127_920833_0 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 556.0
PYH2_k127_920833_1 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 477.0
PYH2_k127_920833_10 Protein of unknown function (DUF3096) - - - 0.00000000000002944 73.0
PYH2_k127_920833_11 PFAM AMP-dependent synthetase and ligase - - - 0.000000003385 61.0
PYH2_k127_920833_12 - - - - 0.0003371 47.0
PYH2_k127_920833_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
PYH2_k127_920833_3 crp fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000304 281.0
PYH2_k127_920833_4 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004369 275.0
PYH2_k127_920833_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
PYH2_k127_920833_6 PFAM transport-associated K04065 - - 0.000000000000000000000000000000000001988 139.0
PYH2_k127_920833_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001495 136.0
PYH2_k127_920833_8 PFAM transport-associated K04065 - - 0.00000000000000000000000000007992 119.0
PYH2_k127_920833_9 NADH dehydrogenase K03885,K17218 - 1.6.99.3,1.8.5.4 0.00000000000000000000002831 106.0
PYH2_k127_9302483_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 507.0
PYH2_k127_9302483_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 407.0
PYH2_k127_9302483_10 PFAM thioesterase superfamily protein K01075 - 3.1.2.23 0.00000000000000000000005518 103.0
PYH2_k127_9302483_11 Domain of unknown function (DUF1992) - - - 0.0000000000000000000009623 99.0
PYH2_k127_9302483_2 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 391.0
PYH2_k127_9302483_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
PYH2_k127_9302483_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
PYH2_k127_9302483_5 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 293.0
PYH2_k127_9302483_6 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 287.0
PYH2_k127_9302483_7 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000004989 196.0
PYH2_k127_9302483_8 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000001371 179.0
PYH2_k127_9302483_9 GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001328 130.0
PYH2_k127_947220_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 445.0
PYH2_k127_947220_1 Hydrogenase K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 424.0
PYH2_k127_947220_2 Ni,Fe-hydrogenase I large subunit - - - 0.000000000000000000000000000000000000000000000000000006631 204.0
PYH2_k127_947220_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000002599 152.0
PYH2_k127_947220_4 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000000000004516 143.0
PYH2_k127_947220_5 Rubredoxin - - - 0.00000000002368 63.0
PYH2_k127_957417_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 8.5e-305 945.0
PYH2_k127_957417_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.042e-216 686.0
PYH2_k127_957417_2 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 374.0
PYH2_k127_957417_3 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000008896 128.0
PYH2_k127_961803_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.344e-200 650.0
PYH2_k127_989837_0 ABC transporter C-terminal domain K06158 - - 1.948e-260 816.0
PYH2_k127_989837_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 529.0
PYH2_k127_989837_11 Protein of unknown function (DUF1847) - - - 0.0005809 42.0
PYH2_k127_989837_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
PYH2_k127_989837_3 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 376.0
PYH2_k127_989837_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
PYH2_k127_989837_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
PYH2_k127_989837_6 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
PYH2_k127_989837_7 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000003088 83.0
PYH2_k127_989837_8 Protein of unknown function (DUF1847) - - - 0.00000000000000004417 88.0
PYH2_k127_989837_9 Protein of unknown function (DUF1847) - - - 0.000000001951 62.0