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Overview

ID MAG03181
Name PYH2_bin.24
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family JAFGLR01
Genus JAFGLR01
Species
Assembly information
Completeness (%) 80.62
Contamination (%) 3.1
GC content (%) 50.0
N50 (bp) 4,236
Genome size (bp) 1,606,445

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1579

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1028239_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 409.0
PYH2_k127_1028239_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 290.0
PYH2_k127_1033559_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000006645 83.0
PYH2_k127_1046334_0 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 466.0
PYH2_k127_1046334_1 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
PYH2_k127_1088848_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 302.0
PYH2_k127_1088848_1 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000495 255.0
PYH2_k127_1088848_2 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000004341 194.0
PYH2_k127_1088848_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000001168 80.0
PYH2_k127_1088848_4 PAS domain - - - 0.00000000006969 72.0
PYH2_k127_1119671_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.764e-297 929.0
PYH2_k127_1119671_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 548.0
PYH2_k127_1119671_2 GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000001321 157.0
PYH2_k127_1119671_3 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.0000000000000000008978 89.0
PYH2_k127_1126713_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
PYH2_k127_1126713_1 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000009927 216.0
PYH2_k127_1126713_2 KH domain K06346 - - 0.000000000000000000000000000000006376 130.0
PYH2_k127_1126713_3 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00003666 47.0
PYH2_k127_1134360_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1179.0
PYH2_k127_1134360_1 Protein of unknown function (DUF1461) - - - 0.00000000000000000000000000000000000000002192 162.0
PYH2_k127_1141196_0 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000001876 209.0
PYH2_k127_1141196_1 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000000001965 134.0
PYH2_k127_115037_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000105 296.0
PYH2_k127_115037_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K02003,K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000003332 218.0
PYH2_k127_115037_2 Histidine kinase - - - 0.00000000000000000000000000009019 117.0
PYH2_k127_115037_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000001752 81.0
PYH2_k127_117084_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 409.0
PYH2_k127_117084_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000001251 240.0
PYH2_k127_117084_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000002454 212.0
PYH2_k127_117084_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000001804 175.0
PYH2_k127_117084_4 Probable zinc-ribbon domain - - - 0.000000000000004123 78.0
PYH2_k127_117084_5 Stage II sporulation protein M K06384 - - 0.000000000000006922 82.0
PYH2_k127_117084_6 Probable zinc-ribbon domain - - - 0.00000001528 55.0
PYH2_k127_117084_7 Protein of unknown function (DUF541) K09807 - - 0.0002298 44.0
PYH2_k127_1171422_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000001771 243.0
PYH2_k127_1171422_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000276 134.0
PYH2_k127_1224222_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 494.0
PYH2_k127_1224222_1 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 486.0
PYH2_k127_1224222_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 459.0
PYH2_k127_1224222_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000329 226.0
PYH2_k127_1224222_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001823 165.0
PYH2_k127_1224222_5 methionine transport K02071 - - 0.000000000004554 67.0
PYH2_k127_1231810_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001248 248.0
PYH2_k127_1231810_1 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000002017 212.0
PYH2_k127_1231810_2 FMN binding - - - 0.0000000000006293 76.0
PYH2_k127_1237702_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000001922 104.0
PYH2_k127_1237702_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000002111 63.0
PYH2_k127_129350_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.841e-247 775.0
PYH2_k127_129350_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000004239 117.0
PYH2_k127_1307473_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 509.0
PYH2_k127_1307473_1 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000005515 134.0
PYH2_k127_1307473_2 Cytochrome c - - - 0.00000000000005881 76.0
PYH2_k127_1341690_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009174 278.0
PYH2_k127_1395086_0 NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 372.0
PYH2_k127_1395086_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 326.0
PYH2_k127_1395086_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 306.0
PYH2_k127_1395086_3 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000008353 150.0
PYH2_k127_1395086_4 MmgE/PrpD family - - - 0.0000000000000000000000002166 121.0
PYH2_k127_1416422_0 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 493.0
PYH2_k127_1416422_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 307.0
PYH2_k127_1416422_2 COG0534 Na -driven multidrug efflux pump - - - 0.000000000000000000000000000009961 128.0
PYH2_k127_1416422_3 MatE - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000003929 108.0
PYH2_k127_1416422_4 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000001797 85.0
PYH2_k127_1416483_0 alpha-L-arabinofuranosidase - - - 0.00000000003106 72.0
PYH2_k127_1420126_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.726e-271 842.0
PYH2_k127_1420126_1 Poly A polymerase head domain K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 304.0
PYH2_k127_1420126_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001638 213.0
PYH2_k127_1420126_3 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000135 181.0
PYH2_k127_1420126_4 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000001043 154.0
PYH2_k127_1420126_5 AAA domain - - - 0.0000000000006144 69.0
PYH2_k127_1438781_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.493e-306 953.0
PYH2_k127_1441323_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 313.0
PYH2_k127_1441323_1 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000000000000000000000000003066 190.0
PYH2_k127_1441323_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000004751 131.0
PYH2_k127_1448355_0 PFAM 4Fe-4S binding domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 239.0
PYH2_k127_1448355_1 Polysulphide reductase, NrfD - - - 0.000000000000000000002458 104.0
PYH2_k127_1448355_2 PFAM Nitrate reductase delta subunit - - - 0.0000000001146 70.0
PYH2_k127_1451138_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 564.0
PYH2_k127_1501316_0 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
PYH2_k127_1501316_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
PYH2_k127_1501316_2 PFAM glutaredoxin - - - 0.0000000000000000000000000000418 121.0
PYH2_k127_1503336_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 285.0
PYH2_k127_1503336_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001395 285.0
PYH2_k127_1503336_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000003155 151.0
PYH2_k127_1561297_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 7.565e-195 651.0
PYH2_k127_1561297_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K07469,K11177 - 1.17.1.4,1.2.5.3,1.2.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 636.0
PYH2_k127_1568787_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 532.0
PYH2_k127_1568787_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 506.0
PYH2_k127_1568787_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 358.0
PYH2_k127_1568787_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
PYH2_k127_1568787_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001298 253.0
PYH2_k127_1568787_5 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000009207 179.0
PYH2_k127_1568787_6 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000002137 149.0
PYH2_k127_1571996_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 455.0
PYH2_k127_1571996_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000004983 237.0
PYH2_k127_1571996_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000006421 166.0
PYH2_k127_1571996_3 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.00000000002823 74.0
PYH2_k127_15753_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 534.0
PYH2_k127_15753_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 327.0
PYH2_k127_1598019_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 498.0
PYH2_k127_1598019_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 404.0
PYH2_k127_159954_0 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002328 269.0
PYH2_k127_159954_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000002789 138.0
PYH2_k127_1617512_0 carotenoid biosynthetic process K10212 - - 0.0000000000000000000000000000003014 128.0
PYH2_k127_1617512_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000002935 51.0
PYH2_k127_1622125_0 TIGRFAM sodium ion-translocating decarboxylase, beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 482.0
PYH2_k127_1622125_1 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000000000000000000000000000000000003056 217.0
PYH2_k127_1622125_2 Cytidylate kinase-like family - - - 0.00000000000001262 81.0
PYH2_k127_1623712_0 NifU-like domain - - - 0.0000000000000000000004685 99.0
PYH2_k127_1623712_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000001759 98.0
PYH2_k127_1666915_0 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 629.0
PYH2_k127_1691479_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 555.0
PYH2_k127_1705657_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 427.0
PYH2_k127_1705657_1 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 375.0
PYH2_k127_1705657_2 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 349.0
PYH2_k127_1705657_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 323.0
PYH2_k127_1705657_4 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006387 276.0
PYH2_k127_1705657_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000008403 104.0
PYH2_k127_171972_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 536.0
PYH2_k127_171972_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000008079 165.0
PYH2_k127_1734632_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 589.0
PYH2_k127_1734632_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.00000000000000000000000000000000007104 135.0
PYH2_k127_1737432_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 583.0
PYH2_k127_1737432_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 313.0
PYH2_k127_1737432_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001269 233.0
PYH2_k127_1737432_3 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000008247 213.0
PYH2_k127_1737432_4 peptidase U32 - - - 0.000000000000000000000000256 107.0
PYH2_k127_1737432_5 - - - - 0.00000000000004158 74.0
PYH2_k127_1742358_0 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 456.0
PYH2_k127_1742358_1 Thioesterase superfamily K02614 - - 0.000000000000000000000000007834 114.0
PYH2_k127_1744207_0 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 308.0
PYH2_k127_1744207_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K03520 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001023 273.0
PYH2_k127_1744207_2 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000107 192.0
PYH2_k127_1763823_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 541.0
PYH2_k127_1763823_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 423.0
PYH2_k127_179581_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 587.0
PYH2_k127_179581_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 334.0
PYH2_k127_179581_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
PYH2_k127_179581_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000004928 236.0
PYH2_k127_179581_4 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000001503 179.0
PYH2_k127_179581_5 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000002788 124.0
PYH2_k127_1805644_0 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 334.0
PYH2_k127_1805644_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000867 271.0
PYH2_k127_1805644_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000007688 93.0
PYH2_k127_1805644_3 4-hydroxyphenylacetate K14534 - 4.2.1.120,5.3.3.3 0.000000001843 59.0
PYH2_k127_1848406_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 308.0
PYH2_k127_1848406_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000002998 186.0
PYH2_k127_1848406_2 Sigma-70, region 4 type 2 - - - 0.00000000000000000001582 93.0
PYH2_k127_1863605_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000002001 165.0
PYH2_k127_1863605_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000000003993 105.0
PYH2_k127_1865638_0 - - - - 0.00000000000002253 74.0
PYH2_k127_1865638_1 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.00000001089 66.0
PYH2_k127_1866076_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 609.0
PYH2_k127_1880670_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
PYH2_k127_1880670_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 249.0
PYH2_k127_1892308_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 542.0
PYH2_k127_1892308_1 Histidine kinase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008635 286.0
PYH2_k127_1892308_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000004948 168.0
PYH2_k127_1892308_3 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000001389 99.0
PYH2_k127_1905722_0 Periplasmic Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002364 265.0
PYH2_k127_1918509_0 - - - - 0.000000000005956 71.0
PYH2_k127_1933385_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 341.0
PYH2_k127_1933385_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008307 259.0
PYH2_k127_1933385_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000006152 195.0
PYH2_k127_1933385_3 phosphorelay signal transduction system - - - 0.000003549 49.0
PYH2_k127_1955476_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 511.0
PYH2_k127_1955476_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
PYH2_k127_1955476_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000007223 169.0
PYH2_k127_1955476_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000857 53.0
PYH2_k127_2010079_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 344.0
PYH2_k127_2010079_1 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
PYH2_k127_2029116_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 373.0
PYH2_k127_2029116_1 Trehalase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005786 265.0
PYH2_k127_2029116_2 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000004187 213.0
PYH2_k127_2029116_3 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000001781 188.0
PYH2_k127_2029116_4 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000003855 151.0
PYH2_k127_2029116_5 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000002949 96.0
PYH2_k127_2029116_6 transposition - - - 0.0000000000003766 71.0
PYH2_k127_2029116_7 - - - - 0.00000000001531 74.0
PYH2_k127_2029116_8 domain protein K02005,K06006,K07803,K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000001839 67.0
PYH2_k127_2029116_9 Phage integrase, N-terminal SAM-like domain - - - 0.000003296 50.0
PYH2_k127_2032437_0 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 515.0
PYH2_k127_2032437_1 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000185 114.0
PYH2_k127_2032437_2 - - - - 0.0000000000000000006059 97.0
PYH2_k127_2045738_0 Ferrous iron transport protein B K04759 - - 4.579e-252 792.0
PYH2_k127_2051851_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 520.0
PYH2_k127_2051851_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 398.0
PYH2_k127_2123732_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001142 266.0
PYH2_k127_2123732_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000009217 208.0
PYH2_k127_2132810_0 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000002883 188.0
PYH2_k127_2132810_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000006663 136.0
PYH2_k127_2153720_0 Alpha-2-macroglobulin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 481.0
PYH2_k127_2153720_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 317.0
PYH2_k127_2153720_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001126 261.0
PYH2_k127_217633_0 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 348.0
PYH2_k127_217633_1 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008017 244.0
PYH2_k127_2176497_0 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K17735 - 1.1.1.108,1.1.1.157 0.00000000000000000000000000000000000000000000000000003254 199.0
PYH2_k127_2193494_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 4.969e-194 616.0
PYH2_k127_2193494_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 521.0
PYH2_k127_2193494_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000001126 150.0
PYH2_k127_2230226_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007208 235.0
PYH2_k127_2230226_1 ECF sigma factor K03088 - - 0.0000000000000000000000000004439 121.0
PYH2_k127_2230226_2 - - - - 0.00008506 49.0
PYH2_k127_2247876_0 Putative Ig domain - - - 0.0000000000000000000000000000000001234 143.0
PYH2_k127_2247876_1 - - - - 0.0000000000000000004618 88.0
PYH2_k127_2250665_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 329.0
PYH2_k127_2250665_1 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000182 144.0
PYH2_k127_2256142_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 435.0
PYH2_k127_2256142_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 426.0
PYH2_k127_2256142_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000005344 113.0
PYH2_k127_225914_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1158.0
PYH2_k127_225914_1 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000012 177.0
PYH2_k127_225914_2 - - - - 0.000000000000000000000001748 113.0
PYH2_k127_225914_3 Recombinase zinc beta ribbon domain - - - 0.00000000000000002466 84.0
PYH2_k127_225914_4 methyltransferase K16648 - - 0.0004732 49.0
PYH2_k127_2297650_0 ABC-type multidrug transport system ATPase and permease K06147 - - 6.687e-259 818.0
PYH2_k127_2297650_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 580.0
PYH2_k127_2297650_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 361.0
PYH2_k127_2297650_3 Transmembrane secretion effector K08217 - - 0.000000000000000000000000000000000000000000000000001653 199.0
PYH2_k127_2297650_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000001502 120.0
PYH2_k127_2306771_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.879e-249 781.0
PYH2_k127_2306771_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 326.0
PYH2_k127_2306771_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 325.0
PYH2_k127_231339_0 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000003887 180.0
PYH2_k127_2345444_0 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 420.0
PYH2_k127_2345444_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 375.0
PYH2_k127_2345444_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 358.0
PYH2_k127_2345444_3 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.00000000000000000000000000000000001999 142.0
PYH2_k127_2345444_4 - - - - 0.0006968 44.0
PYH2_k127_2369417_0 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases K01081,K07004,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000003816 210.0
PYH2_k127_2369417_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000843 61.0
PYH2_k127_2376120_0 III protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 421.0
PYH2_k127_2376120_1 Belongs to the enoyl-CoA hydratase isomerase family - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000006043 210.0
PYH2_k127_2376120_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000003628 198.0
PYH2_k127_2376120_3 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000000000000000000000000000000000000000000003595 193.0
PYH2_k127_2376120_4 - - - - 0.00000000000959 67.0
PYH2_k127_2376120_5 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.0000000003326 62.0
PYH2_k127_2376120_6 - - - - 0.000000005181 59.0
PYH2_k127_2380963_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001877 279.0
PYH2_k127_2380963_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000004988 89.0
PYH2_k127_2403106_0 4Fe-4S dicluster domain - - - 4.251e-267 829.0
PYH2_k127_2403106_1 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
PYH2_k127_2403106_2 - - - - 0.0000000000216 67.0
PYH2_k127_2409894_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001809 256.0
PYH2_k127_2409894_1 integral membrane protein - - - 0.000000000000000000000000000000000000548 151.0
PYH2_k127_2409894_2 Diacylglycerol kinase catalytic domain - - - 0.00000000008849 63.0
PYH2_k127_2421618_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
PYH2_k127_2421618_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000536 57.0
PYH2_k127_2444783_0 R3H domain - - - 7.39e-203 643.0
PYH2_k127_2444783_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 438.0
PYH2_k127_2444783_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 343.0
PYH2_k127_2444783_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000009041 222.0
PYH2_k127_244850_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 472.0
PYH2_k127_244850_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
PYH2_k127_244850_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000005431 175.0
PYH2_k127_244850_3 electron transfer activity K05337 - - 0.00000001502 58.0
PYH2_k127_2464502_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.593e-220 699.0
PYH2_k127_2464502_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000002469 128.0
PYH2_k127_2464502_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0006291 42.0
PYH2_k127_2479747_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
PYH2_k127_2479747_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008612 267.0
PYH2_k127_2479747_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000964 214.0
PYH2_k127_2479747_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00004872 46.0
PYH2_k127_2488808_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 474.0
PYH2_k127_2488808_1 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 312.0
PYH2_k127_2488808_2 Glutaredoxin K03676,K04771 - 3.4.21.107 0.00000000000000000000000000000000006566 138.0
PYH2_k127_2488808_3 phosphatase 2c K14497 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009787,GO:0009788,GO:0009966,GO:0009968,GO:0009987,GO:0010029,GO:0010030,GO:0010646,GO:0010648,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0023051,GO:0023057,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0048518,GO:0048519,GO:0048523,GO:0048580,GO:0048582,GO:0048583,GO:0048585,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051239,GO:0051240,GO:0065007,GO:0071704,GO:0140096,GO:1900140,GO:1901419,GO:1901420,GO:1901564,GO:1905957,GO:1905958,GO:2000026 3.1.3.16 0.000000000000000000000007054 109.0
PYH2_k127_2527085_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 610.0
PYH2_k127_2527085_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 579.0
PYH2_k127_2527085_10 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000131 102.0
PYH2_k127_2527085_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 435.0
PYH2_k127_2527085_3 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 327.0
PYH2_k127_2527085_4 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001016 269.0
PYH2_k127_2527085_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000001286 264.0
PYH2_k127_2527085_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
PYH2_k127_2527085_7 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000007781 238.0
PYH2_k127_2527085_8 cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
PYH2_k127_2527085_9 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000003388 208.0
PYH2_k127_2529067_0 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000009957 188.0
PYH2_k127_2529957_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 490.0
PYH2_k127_2529957_1 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001152 93.0
PYH2_k127_2529957_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000004144 53.0
PYH2_k127_2577150_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 570.0
PYH2_k127_2681042_0 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0 1482.0
PYH2_k127_2681042_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 388.0
PYH2_k127_2681042_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 300.0
PYH2_k127_2681042_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 294.0
PYH2_k127_2681042_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001892 281.0
PYH2_k127_2681042_5 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
PYH2_k127_2681042_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000003549 119.0
PYH2_k127_2681042_7 Transcriptional regulator, arsR family - - - 0.00000000000000000006103 93.0
PYH2_k127_2681042_9 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 GO:0000054,GO:0000166,GO:0000956,GO:0001558,GO:0001959,GO:0002682,GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006403,GO:0006405,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008428,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009966,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010941,GO:0015031,GO:0015833,GO:0015931,GO:0016043,GO:0016070,GO:0016071,GO:0017076,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0022613,GO:0023051,GO:0030234,GO:0030554,GO:0031323,GO:0031324,GO:0031347,GO:0031369,GO:0031503,GO:0031974,GO:0032069,GO:0032074,GO:0032553,GO:0032555,GO:0032559,GO:0032790,GO:0032984,GO:0032988,GO:0033036,GO:0033750,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0035639,GO:0036094,GO:0040008,GO:0042254,GO:0042886,GO:0042981,GO:0043021,GO:0043024,GO:0043043,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043523,GO:0043524,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045088,GO:0045184,GO:0045934,GO:0046483,GO:0046700,GO:0046872,GO:0046907,GO:0046914,GO:0048519,GO:0048523,GO:0048583,GO:0050657,GO:0050658,GO:0050776,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051168,GO:0051169,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051236,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0060255,GO:0060338,GO:0060548,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0060759,GO:0065007,GO:0065009,GO:0070013,GO:0070481,GO:0070727,GO:0071166,GO:0071426,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097367,GO:0098772,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000002231 52.0
PYH2_k127_2733658_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000001723 169.0
PYH2_k127_2733658_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000002627 111.0
PYH2_k127_2746029_0 Dak1_2 K07030 - - 2.831e-205 652.0
PYH2_k127_2746029_1 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 490.0
PYH2_k127_2746029_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002559 265.0
PYH2_k127_2746029_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
PYH2_k127_2746029_4 Ribosomal L28 family K02902 - - 0.00000000000000000004572 92.0
PYH2_k127_274901_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.764e-220 698.0
PYH2_k127_274901_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 333.0
PYH2_k127_274901_2 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002082 282.0
PYH2_k127_2775129_0 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 496.0
PYH2_k127_2775129_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000003086 115.0
PYH2_k127_2799454_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 415.0
PYH2_k127_2799454_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 308.0
PYH2_k127_2799454_2 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 282.0
PYH2_k127_2799454_3 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000002522 139.0
PYH2_k127_282013_0 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 432.0
PYH2_k127_282013_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 329.0
PYH2_k127_282013_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000319 262.0
PYH2_k127_282013_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000002287 256.0
PYH2_k127_282013_4 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000006798 197.0
PYH2_k127_282013_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000005653 137.0
PYH2_k127_2829853_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 392.0
PYH2_k127_2829853_1 Major facilitator superfamily K03449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 392.0
PYH2_k127_2829853_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000004867 139.0
PYH2_k127_2829853_11 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000003291 130.0
PYH2_k127_2829853_12 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000001919 111.0
PYH2_k127_2829853_13 Lrp/AsnC ligand binding domain - - - 0.000000000000000000007743 94.0
PYH2_k127_2829853_14 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.000000000000001573 77.0
PYH2_k127_2829853_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0003497 47.0
PYH2_k127_2829853_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 343.0
PYH2_k127_2829853_3 Acetyl xylan esterase (AXE1) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 311.0
PYH2_k127_2829853_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 310.0
PYH2_k127_2829853_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 295.0
PYH2_k127_2829853_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
PYH2_k127_2829853_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000001563 205.0
PYH2_k127_2829853_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000009816 199.0
PYH2_k127_2829853_9 Rhomboid family - - - 0.00000000000000000000000000000000000000000001342 170.0
PYH2_k127_283549_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 5.51e-224 704.0
PYH2_k127_283549_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 464.0
PYH2_k127_283549_2 Protein of unknown function (DUF1015) - - - 0.0000000009698 59.0
PYH2_k127_2849615_0 belongs to the thioredoxin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 275.0
PYH2_k127_2849615_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000009161 243.0
PYH2_k127_2850534_0 ATPase AAA-2 domain protein K03696 - - 0.0 1051.0
PYH2_k127_2850534_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 492.0
PYH2_k127_2850534_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 416.0
PYH2_k127_2850534_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 391.0
PYH2_k127_2850534_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 315.0
PYH2_k127_2850534_5 Glutamine amidotransferase class-I - - - 0.0000000000000000000000003194 110.0
PYH2_k127_2850534_6 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000162 81.0
PYH2_k127_2850534_7 CTP synthase K01937 - 6.3.4.2 0.000000000000111 74.0
PYH2_k127_2850534_8 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.000000000007981 68.0
PYH2_k127_2850534_9 - - - - 0.00000000002238 65.0
PYH2_k127_2903316_0 Thymidylate synthase K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 331.0
PYH2_k127_2903316_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
PYH2_k127_2903316_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001532 259.0
PYH2_k127_2903316_3 - - - - 0.00000000000000000000000000000000000000004954 158.0
PYH2_k127_2903316_4 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000000000000000000001206 111.0
PYH2_k127_2903316_5 YHS domain - - - 0.000000000000005079 76.0
PYH2_k127_2907526_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 587.0
PYH2_k127_2907526_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 529.0
PYH2_k127_2907526_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000001421 101.0
PYH2_k127_2907526_3 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.0000000008418 59.0
PYH2_k127_2922316_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 454.0
PYH2_k127_2922316_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 337.0
PYH2_k127_2960876_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003687 274.0
PYH2_k127_2960876_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000004185 226.0
PYH2_k127_2960876_2 succinate dehydrogenase K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 0.0000000008536 63.0
PYH2_k127_2960876_3 dolichyl monophosphate biosynthetic process - - - 0.000007195 53.0
PYH2_k127_2996464_0 Nitroreductase family - - - 0.0000000000000000005312 95.0
PYH2_k127_2996464_1 Amidohydrolase K03392,K07045,K20941 - 4.1.1.103,4.1.1.45 0.000000000002126 70.0
PYH2_k127_2996464_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000003508 73.0
PYH2_k127_3002218_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 469.0
PYH2_k127_3002218_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008161 268.0
PYH2_k127_3002218_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000008624 220.0
PYH2_k127_3005165_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1401.0
PYH2_k127_3005165_1 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001324 269.0
PYH2_k127_3005165_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000679 108.0
PYH2_k127_3005165_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000003634 97.0
PYH2_k127_3005165_12 KH domain K06346 - - 0.000000000000000004433 92.0
PYH2_k127_3005165_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000079 87.0
PYH2_k127_3005165_14 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000002727 76.0
PYH2_k127_3005165_15 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000002765 75.0
PYH2_k127_3005165_2 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000000115 211.0
PYH2_k127_3005165_3 - - - - 0.000000000000000000000000000000000000000000000002855 182.0
PYH2_k127_3005165_4 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000001546 177.0
PYH2_k127_3005165_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000003049 172.0
PYH2_k127_3005165_6 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000251 158.0
PYH2_k127_3005165_7 - - - - 0.0000000000000000000000000000000006291 132.0
PYH2_k127_3005165_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000002489 129.0
PYH2_k127_3005165_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000009929 119.0
PYH2_k127_3026172_0 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 389.0
PYH2_k127_3026172_1 Methyltransferase domain - - - 0.00000002049 61.0
PYH2_k127_3026172_2 SNARE associated Golgi protein - - - 0.00000004412 62.0
PYH2_k127_303980_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00123,K00266 - 1.17.1.9,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 474.0
PYH2_k127_303980_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 448.0
PYH2_k127_303980_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000002592 172.0
PYH2_k127_303980_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000003412 157.0
PYH2_k127_3042867_0 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 484.0
PYH2_k127_3042867_1 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003545 241.0
PYH2_k127_3042867_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000001313 108.0
PYH2_k127_3042867_3 Putative regulatory protein - - - 0.0000000000000008517 81.0
PYH2_k127_3046820_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 395.0
PYH2_k127_3046820_1 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
PYH2_k127_3046820_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008169 259.0
PYH2_k127_3046820_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002033 253.0
PYH2_k127_3046820_4 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000004863 155.0
PYH2_k127_3046820_5 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.00000000000000000000000000000000000008807 156.0
PYH2_k127_3046820_6 PFAM MaoC like domain - - - 0.0000000000000000000000000002043 121.0
PYH2_k127_3046820_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.0000007778 53.0
PYH2_k127_3046820_9 dehydratase - - - 0.00006204 50.0
PYH2_k127_3049486_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 455.0
PYH2_k127_3049486_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 301.0
PYH2_k127_3049486_2 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
PYH2_k127_3049486_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000005955 82.0
PYH2_k127_3077996_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 313.0
PYH2_k127_3077996_1 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 301.0
PYH2_k127_3077996_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001519 250.0
PYH2_k127_3077996_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000001309 244.0
PYH2_k127_309207_0 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000004671 58.0
PYH2_k127_3105043_0 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 402.0
PYH2_k127_3105043_1 Glutamine cyclotransferase K00683 - 2.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001421 260.0
PYH2_k127_3105043_2 PFAM Major Facilitator Superfamily - - - 0.0000002007 55.0
PYH2_k127_3138963_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
PYH2_k127_3138963_1 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000001096 204.0
PYH2_k127_3138963_2 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000005882 88.0
PYH2_k127_315504_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000001923 175.0
PYH2_k127_315504_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000003354 55.0
PYH2_k127_3161451_0 ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 331.0
PYH2_k127_3161451_1 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 321.0
PYH2_k127_3238264_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000007552 126.0
PYH2_k127_3238264_1 RNase_H superfamily K07502 - - 0.0000001014 55.0
PYH2_k127_3258871_0 Fumarate reductase flavoprotein C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008162 261.0
PYH2_k127_3258871_1 TIGRFAM degV family protein - - - 0.0000000000000000000000000000000237 137.0
PYH2_k127_3275418_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 7.998e-230 719.0
PYH2_k127_3279051_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 496.0
PYH2_k127_3323722_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
PYH2_k127_3323722_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001837 284.0
PYH2_k127_3331203_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 497.0
PYH2_k127_3334579_0 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 346.0
PYH2_k127_3334579_1 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 273.0
PYH2_k127_3334579_2 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
PYH2_k127_3334579_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000106 169.0
PYH2_k127_3334579_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000489 155.0
PYH2_k127_3334579_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000123 120.0
PYH2_k127_3334579_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000001916 113.0
PYH2_k127_3334579_7 Binds the 23S rRNA K02909 - - 0.00000000000000000000000007414 107.0
PYH2_k127_3339678_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 457.0
PYH2_k127_3339678_1 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 304.0
PYH2_k127_3339678_2 Cyclophilin-like K09143 - - 0.0000000000000000000001867 98.0
PYH2_k127_3353499_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000719 180.0
PYH2_k127_3353499_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000002777 80.0
PYH2_k127_3370774_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
PYH2_k127_3370774_1 GYD domain - - - 0.0000000000000000000000005865 107.0
PYH2_k127_3370774_2 - - - - 0.00000000001395 68.0
PYH2_k127_3384037_0 AraC-like ligand binding domain - - - 0.000000000000009918 79.0
PYH2_k127_3384037_1 PFAM Major Facilitator Superfamily - - - 0.00000000002274 74.0
PYH2_k127_3384037_2 Glucokinase K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.000009229 49.0
PYH2_k127_3393079_0 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 484.0
PYH2_k127_3393079_1 pfam abc-1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 394.0
PYH2_k127_3393079_2 peptidase, M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004289 254.0
PYH2_k127_3393079_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000005275 237.0
PYH2_k127_3393079_4 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000003675 226.0
PYH2_k127_3393079_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000004487 188.0
PYH2_k127_3393079_6 UBA TS-N domain - - - 0.000005778 50.0
PYH2_k127_3393079_7 - - - - 0.00002032 48.0
PYH2_k127_3395454_0 DNA modification repair radical SAM protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005192 252.0
PYH2_k127_3395454_1 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000144 81.0
PYH2_k127_3424262_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.784e-241 768.0
PYH2_k127_3424262_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 613.0
PYH2_k127_3424262_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 507.0
PYH2_k127_3424262_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 421.0
PYH2_k127_3424262_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 347.0
PYH2_k127_3424262_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000003584 208.0
PYH2_k127_3424262_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000001202 141.0
PYH2_k127_3424262_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000008306 76.0
PYH2_k127_3425942_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002687 241.0
PYH2_k127_3425942_1 Thioredoxin - - - 0.00000000000000000000000001243 116.0
PYH2_k127_3425942_2 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000002893 66.0
PYH2_k127_3440139_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000522 218.0
PYH2_k127_3440139_1 Response regulator receiver - - - 0.000000000000000000000000000000000000001442 150.0
PYH2_k127_3440139_2 - - - - 0.0000000000000000000000000000000008663 141.0
PYH2_k127_3460700_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 2.302e-289 914.0
PYH2_k127_3460700_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002172 244.0
PYH2_k127_3460700_3 DNA integration - - - 0.000004319 50.0
PYH2_k127_3479353_0 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 293.0
PYH2_k127_3479353_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000001126 84.0
PYH2_k127_3488190_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000009187 96.0
PYH2_k127_3488190_1 Arylsulfotransferase (ASST) - - - 0.00000217 51.0
PYH2_k127_3555396_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 321.0
PYH2_k127_3555396_1 - - - - 0.00000000000000000000001114 108.0
PYH2_k127_3581330_0 Elongation factor G C-terminus K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 348.0
PYH2_k127_3596851_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 336.0
PYH2_k127_3596851_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000002791 184.0
PYH2_k127_3656044_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000001503 229.0
PYH2_k127_3656700_0 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002393 237.0
PYH2_k127_3656700_1 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000005303 142.0
PYH2_k127_3670096_0 - - - - 0.0000000000000000000000000000000000000000000005256 178.0
PYH2_k127_3724108_0 AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 481.0
PYH2_k127_3779875_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 528.0
PYH2_k127_3779875_1 Stress-responsive transcriptional regulator K03973 - - 0.00000000000000001483 88.0
PYH2_k127_3779875_2 - - - - 0.000000000003661 77.0
PYH2_k127_3779875_3 Rhs family - - - 0.0007723 51.0
PYH2_k127_3788231_0 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000009306 175.0
PYH2_k127_3788231_1 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.000000000000000000001626 99.0
PYH2_k127_3808830_0 Pyruvate formate lyase-like K07540 - 4.1.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 533.0
PYH2_k127_3808830_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 484.0
PYH2_k127_3808830_2 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 420.0
PYH2_k127_3808830_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 408.0
PYH2_k127_3808830_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000003147 209.0
PYH2_k127_3808830_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000291 198.0
PYH2_k127_3815730_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000001013 211.0
PYH2_k127_3815730_1 dUTPase K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000007105 191.0
PYH2_k127_3815730_2 Recombinase zinc beta ribbon domain - - - 0.00000000000001974 83.0
PYH2_k127_3815730_3 Diacylglycerol kinase catalytic domain - - - 0.0005076 46.0
PYH2_k127_3817127_0 AAA-like domain K06915 - - 2.482e-230 725.0
PYH2_k127_3817127_1 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 363.0
PYH2_k127_3817127_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
PYH2_k127_3817127_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 287.0
PYH2_k127_3817127_4 PFAM HAS barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
PYH2_k127_3817127_5 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000000000000000000000006025 223.0
PYH2_k127_3817127_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000003112 177.0
PYH2_k127_3817127_7 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000009839 127.0
PYH2_k127_3817127_8 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000008631 57.0
PYH2_k127_3820506_0 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 295.0
PYH2_k127_3820506_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
PYH2_k127_3820506_2 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000006474 81.0
PYH2_k127_3882259_0 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000000000001958 231.0
PYH2_k127_3882259_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000006148 202.0
PYH2_k127_3882259_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000002119 136.0
PYH2_k127_3882259_3 Colicin V production protein K03558 - - 0.0000000000000000000000000000000002078 137.0
PYH2_k127_3889223_0 Helicase C-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000003245 193.0
PYH2_k127_3924892_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1048.0
PYH2_k127_3924892_1 Sugar (and other) transporter - - - 0.0001742 47.0
PYH2_k127_3947951_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 339.0
PYH2_k127_3947951_1 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000348 149.0
PYH2_k127_3960725_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000002071 189.0
PYH2_k127_3960725_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000006182 195.0
PYH2_k127_399798_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000001208 207.0
PYH2_k127_4006997_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.902e-233 737.0
PYH2_k127_4006997_1 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 318.0
PYH2_k127_4006997_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000000000609 184.0
PYH2_k127_4006997_3 RNA methylase - - - 0.0000000000000000000000000000000001485 138.0
PYH2_k127_4006997_4 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.000000000000001741 78.0
PYH2_k127_4131860_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1140.0
PYH2_k127_4131860_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0 1122.0
PYH2_k127_4131860_10 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 310.0
PYH2_k127_4131860_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 309.0
PYH2_k127_4131860_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 298.0
PYH2_k127_4131860_13 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 297.0
PYH2_k127_4131860_14 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001301 279.0
PYH2_k127_4131860_15 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000005098 151.0
PYH2_k127_4131860_16 AMP binding - - - 0.000000000000000000000000000000000453 136.0
PYH2_k127_4131860_17 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000003218 87.0
PYH2_k127_4131860_18 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000837 64.0
PYH2_k127_4131860_19 - - - - 0.000108 48.0
PYH2_k127_4131860_2 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.229e-310 959.0
PYH2_k127_4131860_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.466e-286 891.0
PYH2_k127_4131860_4 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.264e-253 800.0
PYH2_k127_4131860_5 Putative Fe-S cluster K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 561.0
PYH2_k127_4131860_6 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 433.0
PYH2_k127_4131860_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 424.0
PYH2_k127_4131860_8 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 378.0
PYH2_k127_4131860_9 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 350.0
PYH2_k127_4144159_0 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005746 269.0
PYH2_k127_4144159_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0000000000000000000000000000000000000000000000005978 178.0
PYH2_k127_4144159_2 transglycosylase K08309 - - 0.00001125 51.0
PYH2_k127_4145612_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 482.0
PYH2_k127_4145612_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
PYH2_k127_4145612_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.0000000000000000000000127 102.0
PYH2_k127_422883_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 590.0
PYH2_k127_422883_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 441.0
PYH2_k127_422883_2 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000005052 117.0
PYH2_k127_422883_3 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.0000005819 55.0
PYH2_k127_423898_0 PFAM Response regulator receiver domain K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH2_k127_423898_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000004582 161.0
PYH2_k127_423898_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000004209 123.0
PYH2_k127_423898_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00002083 47.0
PYH2_k127_4242000_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 332.0
PYH2_k127_4242000_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000001547 105.0
PYH2_k127_4256792_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 258.0
PYH2_k127_4282458_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000107 252.0
PYH2_k127_4282458_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000003245 146.0
PYH2_k127_4282458_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001245 127.0
PYH2_k127_4282458_3 Ribosomal protein S16 K02959 - - 0.0000000000000000000000001641 108.0
PYH2_k127_4282458_4 KH domain K06960 - - 0.00000000000000000000001706 101.0
PYH2_k127_4315853_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.2e-211 666.0
PYH2_k127_4315853_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 410.0
PYH2_k127_4315853_2 Divergent PAP2 family K09775 - - 0.00000000000000000000000000000002846 130.0
PYH2_k127_4315853_3 - - - - 0.00000000001131 66.0
PYH2_k127_4398790_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
PYH2_k127_4398790_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000008484 222.0
PYH2_k127_4398790_2 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000001478 132.0
PYH2_k127_4398790_3 COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - 0.0000000000000000000000119 107.0
PYH2_k127_4398790_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000009393 89.0
PYH2_k127_4406239_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 298.0
PYH2_k127_4406239_1 PFAM Translin K07477 - - 0.0000000000000000000000000000000000004015 144.0
PYH2_k127_4406239_2 MFS transporter - - - 0.00000000000000000000000000000003803 141.0
PYH2_k127_4415411_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000005488 220.0
PYH2_k127_4415411_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000009515 214.0
PYH2_k127_4415411_2 - - - - 0.00000000000000000000000000000000000000000001074 170.0
PYH2_k127_4415411_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000002868 164.0
PYH2_k127_44326_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.326e-245 765.0
PYH2_k127_44326_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 473.0
PYH2_k127_44326_2 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002358 250.0
PYH2_k127_44326_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000009667 78.0
PYH2_k127_4471254_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.406e-202 640.0
PYH2_k127_4471254_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000003195 222.0
PYH2_k127_4471254_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000001428 199.0
PYH2_k127_4471254_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000004682 154.0
PYH2_k127_4479283_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 593.0
PYH2_k127_4479283_1 PFAM iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 298.0
PYH2_k127_4479283_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001047 186.0
PYH2_k127_4488234_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 319.0
PYH2_k127_4488234_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000125 208.0
PYH2_k127_4488234_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000008281 125.0
PYH2_k127_4488234_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000001351 109.0
PYH2_k127_4492786_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 402.0
PYH2_k127_4492786_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000009606 200.0
PYH2_k127_4500334_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 626.0
PYH2_k127_4500334_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000003331 185.0
PYH2_k127_4535680_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 584.0
PYH2_k127_4535680_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 508.0
PYH2_k127_4535680_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001187 167.0
PYH2_k127_4535680_3 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000176 96.0
PYH2_k127_4584477_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 313.0
PYH2_k127_4584477_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
PYH2_k127_4584477_2 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.00000000000000000000000000000000000022 147.0
PYH2_k127_4662955_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 290.0
PYH2_k127_4662955_1 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000002418 145.0
PYH2_k127_4662955_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000001644 126.0
PYH2_k127_4662955_3 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000001204 60.0
PYH2_k127_4677866_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 547.0
PYH2_k127_4677866_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 544.0
PYH2_k127_4677866_10 ATP binding cassette transporter ABC protein K01990 - - 0.0002646 46.0
PYH2_k127_4677866_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 498.0
PYH2_k127_4677866_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 477.0
PYH2_k127_4677866_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
PYH2_k127_4677866_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000001495 211.0
PYH2_k127_4677866_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000001747 171.0
PYH2_k127_4677866_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000006652 153.0
PYH2_k127_4677866_8 PFAM Uncharacterised protein, DegV family COG1307 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002925 128.0
PYH2_k127_4677866_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000001206 111.0
PYH2_k127_4757603_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 351.0
PYH2_k127_4757603_1 4Fe-4S dicluster domain K00124,K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
PYH2_k127_4778416_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 604.0
PYH2_k127_4778416_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 479.0
PYH2_k127_4778416_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 473.0
PYH2_k127_4778416_3 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000782 256.0
PYH2_k127_4778416_4 NIL - - - 0.00000000000000000000000000000000000000000000000000000001254 200.0
PYH2_k127_4778416_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000002039 143.0
PYH2_k127_4778416_6 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000003522 123.0
PYH2_k127_4778416_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000002769 119.0
PYH2_k127_4817127_0 Elongation factor Tu domain 2 K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 587.0
PYH2_k127_4817127_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 316.0
PYH2_k127_4817127_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000166 244.0
PYH2_k127_4817127_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000005255 184.0
PYH2_k127_4817127_4 TatD related DNase K03424 - - 0.00000000000000000000000000001484 129.0
PYH2_k127_4817127_5 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000009323 116.0
PYH2_k127_4910434_0 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000001854 199.0
PYH2_k127_4910434_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000007306 184.0
PYH2_k127_4910434_2 helix_turn_helix, Lux Regulon K02282 - - 0.0000005554 51.0
PYH2_k127_4918652_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.53e-291 906.0
PYH2_k127_4918652_1 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 578.0
PYH2_k127_4918652_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 428.0
PYH2_k127_4918652_3 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 298.0
PYH2_k127_4918652_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000002721 175.0
PYH2_k127_4919043_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000004234 223.0
PYH2_k127_4919043_1 Belongs to the 'phage' integrase family - - - 0.000000000000000001643 85.0
PYH2_k127_4954546_0 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 1.101e-246 773.0
PYH2_k127_4954546_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.048e-243 760.0
PYH2_k127_4954546_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000002522 237.0
PYH2_k127_4954546_3 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000000001286 94.0
PYH2_k127_4997450_0 peptidase M24 - - - 0.00000000000000000000000000000002996 141.0
PYH2_k127_4997450_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K13775 - - 0.0000000000000000000000000000005625 126.0
PYH2_k127_4997450_2 Metallopeptidase family M24 - - - 0.0000000000000002752 85.0
PYH2_k127_4997450_3 oxalate decarboxylase activity - - - 0.0000000000000003361 83.0
PYH2_k127_4997450_4 Hydantoin racemase K16841 - 5.1.99.3 0.00000000005267 73.0
PYH2_k127_5018253_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 323.0
PYH2_k127_5037045_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 389.0
PYH2_k127_5037045_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000672 268.0
PYH2_k127_5064626_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 539.0
PYH2_k127_5064626_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 385.0
PYH2_k127_5064626_2 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000137 294.0
PYH2_k127_507321_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 418.0
PYH2_k127_507321_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 285.0
PYH2_k127_507321_2 - - - - 0.0000003934 51.0
PYH2_k127_5103757_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 2.723e-287 898.0
PYH2_k127_5103757_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.626e-262 815.0
PYH2_k127_5103757_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.356e-214 671.0
PYH2_k127_5103757_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 477.0
PYH2_k127_5103757_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 302.0
PYH2_k127_5103757_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000008353 229.0
PYH2_k127_5106538_0 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000219 153.0
PYH2_k127_5129559_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 557.0
PYH2_k127_5129559_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 409.0
PYH2_k127_5129559_2 Mannose-6-phosphate isomerase - - - 0.0002224 46.0
PYH2_k127_5135719_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.62e-265 836.0
PYH2_k127_5135719_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
PYH2_k127_5135719_2 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
PYH2_k127_5135719_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000001616 134.0
PYH2_k127_5135719_4 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000003873 134.0
PYH2_k127_5135719_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000006147 106.0
PYH2_k127_5135719_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000148 73.0
PYH2_k127_5147055_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 514.0
PYH2_k127_5147055_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 481.0
PYH2_k127_5147055_2 Family of unknown function (DUF5343) - - - 0.000000000000000000000000000000000000000000000000000000000000001314 225.0
PYH2_k127_5147055_3 - - - - 0.0000000000000000000000000004126 114.0
PYH2_k127_5147055_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000001364 68.0
PYH2_k127_514982_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 573.0
PYH2_k127_514982_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 360.0
PYH2_k127_514982_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002944 261.0
PYH2_k127_514982_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005547 254.0
PYH2_k127_514982_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000114 205.0
PYH2_k127_514982_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000009981 186.0
PYH2_k127_514982_6 structural constituent of ribosome K02879 - - 0.0000000000000000000000000000000000000000002087 162.0
PYH2_k127_514982_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000001209 156.0
PYH2_k127_514982_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004507 153.0
PYH2_k127_514982_9 2 iron, 2 sulfur cluster binding K00087,K03518,K07302,K13483 - 1.17.1.4,1.2.5.3,1.3.99.16 0.0000000000000000004379 87.0
PYH2_k127_5166184_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 568.0
PYH2_k127_5166184_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000159 77.0
PYH2_k127_5166184_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000001394 66.0
PYH2_k127_5190570_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 551.0
PYH2_k127_5190570_1 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 320.0
PYH2_k127_5190570_10 - - - - 0.0000000000000000000000000000000538 126.0
PYH2_k127_5190570_11 - - - - 0.00000000000000000000000000001254 120.0
PYH2_k127_5190570_12 - - - - 0.00000000000000000000000000002962 120.0
PYH2_k127_5190570_13 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000004356 102.0
PYH2_k127_5190570_15 4Fe-4S dicluster domain - - - 0.000000000573 63.0
PYH2_k127_5190570_16 - - - - 0.000000001593 59.0
PYH2_k127_5190570_17 ORF located using Blastx - - - 0.00000002137 56.0
PYH2_k127_5190570_18 - - - - 0.0000006066 51.0
PYH2_k127_5190570_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 282.0
PYH2_k127_5190570_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001994 243.0
PYH2_k127_5190570_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000743 248.0
PYH2_k127_5190570_5 oxidoreductase activity, acting on CH-OH group of donors K18337 - 1.1.1.173,1.1.1.377,1.1.1.378 0.000000000000000000000000000000000000000000000000000001779 201.0
PYH2_k127_5190570_6 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000006547 203.0
PYH2_k127_5190570_7 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000000000000000000000001242 188.0
PYH2_k127_5190570_8 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000002812 177.0
PYH2_k127_5190570_9 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000001866 140.0
PYH2_k127_5297523_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
PYH2_k127_5302430_0 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 429.0
PYH2_k127_5302430_1 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000001126 117.0
PYH2_k127_5302430_2 glutaredoxin-like protein, YruB-family - - - 0.0000000000000000001733 89.0
PYH2_k127_5307917_0 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 420.0
PYH2_k127_5307917_1 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000003639 74.0
PYH2_k127_5312520_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001699 252.0
PYH2_k127_5312520_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000007008 171.0
PYH2_k127_5360768_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 567.0
PYH2_k127_5360768_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 500.0
PYH2_k127_5360768_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001596 232.0
PYH2_k127_5422361_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 450.0
PYH2_k127_5422361_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000001363 138.0
PYH2_k127_5422361_2 dolichyl monophosphate biosynthetic process - - - 0.00000000008465 70.0
PYH2_k127_542560_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 471.0
PYH2_k127_542560_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000161 164.0
PYH2_k127_5429816_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1580.0
PYH2_k127_5429816_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 499.0
PYH2_k127_5429816_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 461.0
PYH2_k127_5429816_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 310.0
PYH2_k127_5429816_4 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 274.0
PYH2_k127_5429816_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000002229 214.0
PYH2_k127_546990_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001201 220.0
PYH2_k127_546990_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000001599 198.0
PYH2_k127_5478799_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 553.0
PYH2_k127_5478799_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 425.0
PYH2_k127_5478799_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 294.0
PYH2_k127_5478799_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000001218 61.0
PYH2_k127_5500892_0 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 5.347e-195 617.0
PYH2_k127_5500892_1 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000005042 243.0
PYH2_k127_5500892_2 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000005513 134.0
PYH2_k127_5500892_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000009521 66.0
PYH2_k127_5562554_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.803e-257 809.0
PYH2_k127_5562554_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000135 215.0
PYH2_k127_5562554_2 tail specific protease K03797 - 3.4.21.102 0.000000000000000001286 86.0
PYH2_k127_5580421_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000006707 229.0
PYH2_k127_5580421_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000001526 191.0
PYH2_k127_5580421_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000000000001343 174.0
PYH2_k127_559310_0 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000652 211.0
PYH2_k127_559310_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000001096 188.0
PYH2_k127_559310_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000216 176.0
PYH2_k127_559310_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000002418 80.0
PYH2_k127_5599162_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
PYH2_k127_5599162_1 Bifunctional nuclease K08999 - - 0.0000000000000000001263 90.0
PYH2_k127_5599162_2 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000006607 51.0
PYH2_k127_5618254_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 359.0
PYH2_k127_5618254_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000001688 184.0
PYH2_k127_5618254_2 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000001869 169.0
PYH2_k127_5618254_3 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000005776 138.0
PYH2_k127_5618254_4 - - - - 0.0000000000000000000007077 103.0
PYH2_k127_5618254_5 oxidoreductase - - - 0.00001795 48.0
PYH2_k127_5623121_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 537.0
PYH2_k127_5623121_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000004797 107.0
PYH2_k127_5623121_2 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000008328 106.0
PYH2_k127_5640192_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 356.0
PYH2_k127_5640192_1 Preprotein translocase subunit K03210 - - 0.00000000000000001279 87.0
PYH2_k127_5655832_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007692 524.0
PYH2_k127_5655832_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 426.0
PYH2_k127_5655832_2 Protein of unknown function (DUF1464) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 295.0
PYH2_k127_5655832_3 endonuclease III - - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
PYH2_k127_5655832_4 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000001497 205.0
PYH2_k127_5655832_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000002312 153.0
PYH2_k127_5655832_6 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000008082 134.0
PYH2_k127_5655832_7 Thiolase, C-terminal domain - - - 0.000000000000000000000000000002076 126.0
PYH2_k127_5655832_8 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000002224 94.0
PYH2_k127_5655832_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000515 82.0
PYH2_k127_5659479_0 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 487.0
PYH2_k127_5659479_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 351.0
PYH2_k127_5659479_2 transmembrane transporter activity K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005134 261.0
PYH2_k127_5659479_3 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000463 186.0
PYH2_k127_5659479_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000007822 96.0
PYH2_k127_5659479_5 PFAM cytochrome c, class I K02030 - - 0.00000182 56.0
PYH2_k127_5660113_0 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
PYH2_k127_5660113_1 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 313.0
PYH2_k127_5660113_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000004918 188.0
PYH2_k127_5660113_3 - K03975 - - 0.00000000000000000000000000000000006515 143.0
PYH2_k127_5660113_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0008002 42.0
PYH2_k127_5663218_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 593.0
PYH2_k127_5663218_1 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 301.0
PYH2_k127_5716144_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000001882 216.0
PYH2_k127_5725107_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000005522 245.0
PYH2_k127_5725107_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000008377 112.0
PYH2_k127_5725796_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 568.0
PYH2_k127_5725796_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 496.0
PYH2_k127_5725796_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001685 235.0
PYH2_k127_5725796_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000002488 199.0
PYH2_k127_5763743_0 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.00000000000000000000000005632 115.0
PYH2_k127_5767898_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000007666 113.0
PYH2_k127_5773098_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 406.0
PYH2_k127_5773098_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 377.0
PYH2_k127_5773098_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 373.0
PYH2_k127_5773098_3 - - - - 0.000000000000000000000000000000008185 129.0
PYH2_k127_5774253_0 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000001253 117.0
PYH2_k127_5774253_1 ABC-2 family transporter protein K01992 - - 0.000000000000001587 78.0
PYH2_k127_5781396_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 366.0
PYH2_k127_5781396_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 364.0
PYH2_k127_5781396_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001459 277.0
PYH2_k127_5781396_3 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000001362 212.0
PYH2_k127_5781396_4 - - - - 0.000000000000000000000000000000000000000000000001026 177.0
PYH2_k127_5781396_5 Regulatory protein, FmdB family - - - 0.0000000005948 63.0
PYH2_k127_5781396_6 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00001278 53.0
PYH2_k127_5791595_0 Iron-sulfur cluster-binding protein K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 476.0
PYH2_k127_5791595_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000309 274.0
PYH2_k127_5791595_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000002406 203.0
PYH2_k127_5794727_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.259e-213 677.0
PYH2_k127_5794727_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 558.0
PYH2_k127_5794727_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 359.0
PYH2_k127_5794727_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 321.0
PYH2_k127_5794727_4 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006523 243.0
PYH2_k127_5794727_5 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000001092 164.0
PYH2_k127_5794727_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002045 141.0
PYH2_k127_5794727_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000007902 87.0
PYH2_k127_5794727_8 Phage integrase family - - - 0.0000000002747 61.0
PYH2_k127_5808593_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.261e-209 662.0
PYH2_k127_5808593_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 490.0
PYH2_k127_5808593_2 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 326.0
PYH2_k127_5808593_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
PYH2_k127_5808593_4 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000001891 175.0
PYH2_k127_5808593_5 - - - - 0.000000006102 62.0
PYH2_k127_5812386_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 457.0
PYH2_k127_5812386_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 406.0
PYH2_k127_5812386_2 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000004629 165.0
PYH2_k127_5812386_3 - - - - 0.000000000000001376 79.0
PYH2_k127_5812707_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002225 273.0
PYH2_k127_582151_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
PYH2_k127_582151_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005005 280.0
PYH2_k127_582151_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000004507 213.0
PYH2_k127_5831026_0 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
PYH2_k127_5831026_1 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 295.0
PYH2_k127_5831026_2 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000004061 243.0
PYH2_k127_5831026_3 PAC2 family - - - 0.000000000000000000000000000000000000000005806 166.0
PYH2_k127_5831026_4 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000004511 152.0
PYH2_k127_5831026_5 - - - - 0.000000000000000001232 89.0
PYH2_k127_5831026_6 - - - - 0.0000272 48.0
PYH2_k127_5848298_0 Belongs to the 5'-nucleotidase family K01081,K07004,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 360.0
PYH2_k127_5891352_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 302.0
PYH2_k127_5891352_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000156 280.0
PYH2_k127_5891352_2 extracellular solute-binding protein, family 1 K05772 - - 0.000000000000000003097 90.0
PYH2_k127_5891352_3 extracellular solute-binding protein, family 1 K05772 - - 0.0000000000000001204 82.0
PYH2_k127_590251_0 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 300.0
PYH2_k127_5911034_0 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 363.0
PYH2_k127_5911034_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000009125 229.0
PYH2_k127_5959534_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000007981 198.0
PYH2_k127_5959534_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000002499 158.0
PYH2_k127_5959534_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000009206 73.0
PYH2_k127_5990350_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 473.0
PYH2_k127_5990350_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000006201 258.0
PYH2_k127_5990350_2 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004215 250.0
PYH2_k127_5990350_3 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000000000000000001235 193.0
PYH2_k127_6064772_0 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005362 263.0
PYH2_k127_6066964_0 methyltransferase activity - - - 0.000000000008076 73.0
PYH2_k127_6088609_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 410.0
PYH2_k127_6088609_1 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000001669 180.0
PYH2_k127_6088609_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000001651 177.0
PYH2_k127_6088609_3 PFAM Cupin - - - 0.0002695 49.0
PYH2_k127_6088609_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0004308 46.0
PYH2_k127_6092814_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 378.0
PYH2_k127_6092814_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000008331 95.0
PYH2_k127_6098994_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.865e-210 657.0
PYH2_k127_6098994_1 Family of unknown function (DUF438) K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 338.0
PYH2_k127_6098994_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 294.0
PYH2_k127_6098994_3 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000105 77.0
PYH2_k127_6098994_4 Hemerythrin HHE cation binding domain K09155 - - 0.000000000001948 70.0
PYH2_k127_6098994_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000003093 52.0
PYH2_k127_6098994_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003068 51.0
PYH2_k127_6131871_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 566.0
PYH2_k127_6131871_1 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 462.0
PYH2_k127_6131871_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000004693 202.0
PYH2_k127_6134449_0 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000002341 113.0
PYH2_k127_6134449_1 SOR/SNZ family K06215 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003922,GO:0005575,GO:0005576,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0017144,GO:0018130,GO:0019344,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000001892 52.0
PYH2_k127_6155342_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 368.0
PYH2_k127_6164035_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 327.0
PYH2_k127_6164035_1 - - - - 0.000000000000000000006835 94.0
PYH2_k127_6164035_2 Cell wall-associated hydrolases (Invasion-associated proteins) - - - 0.0002316 45.0
PYH2_k127_6201802_0 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 334.0
PYH2_k127_6201802_1 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000006603 178.0
PYH2_k127_6201802_2 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000304 139.0
PYH2_k127_6201802_3 PAC2 family - - - 0.00000000000000000000000002416 119.0
PYH2_k127_6207757_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.000000000000000000000000000000000000000000000000000001701 201.0
PYH2_k127_6207757_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000002756 160.0
PYH2_k127_6207757_2 4Fe-4S dicluster domain - - - 0.00000000000000000004951 91.0
PYH2_k127_6238477_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000001782 151.0
PYH2_k127_6238477_1 Phosphotriesterase K07048 - - 0.00000000000000000000000001732 113.0
PYH2_k127_6238477_2 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000131 75.0
PYH2_k127_6238477_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000001143 59.0
PYH2_k127_624838_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 9.494e-207 656.0
PYH2_k127_6260296_0 Psort location Cytoplasmic, score - - - 4.937e-272 857.0
PYH2_k127_6261209_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 325.0
PYH2_k127_6261209_1 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005221 273.0
PYH2_k127_6279103_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 392.0
PYH2_k127_6279103_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 321.0
PYH2_k127_6279103_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
PYH2_k127_6279103_3 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000001764 237.0
PYH2_k127_6279103_4 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000000000000000000000000000000000000000000000002453 211.0
PYH2_k127_6279103_5 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000004637 183.0
PYH2_k127_6279103_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000006243 156.0
PYH2_k127_6279103_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000003093 128.0
PYH2_k127_6293945_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
PYH2_k127_6293945_1 MgtC family K07507 - - 0.00000000000000000000000000000000000969 140.0
PYH2_k127_6320071_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 491.0
PYH2_k127_6320071_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
PYH2_k127_6320071_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000006331 220.0
PYH2_k127_6320071_3 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000002337 185.0
PYH2_k127_6320071_4 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000001628 187.0
PYH2_k127_6320071_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000009266 157.0
PYH2_k127_6320071_6 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000007283 140.0
PYH2_k127_6340130_0 L-lysine catabolic process to acetate - - - 0.0000000000000000000000000000000000000000000000000000000000000000001357 244.0
PYH2_k127_6340130_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000007401 222.0
PYH2_k127_6340130_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000004757 188.0
PYH2_k127_6340130_3 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000001812 166.0
PYH2_k127_6360530_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 449.0
PYH2_k127_6360530_1 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 332.0
PYH2_k127_6360530_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
PYH2_k127_6360530_3 - - - - 0.00000000000000000000000000000000000000000000000000007111 201.0
PYH2_k127_6360530_4 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.0000000000001654 76.0
PYH2_k127_6369510_0 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 239.0
PYH2_k127_6369510_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000005032 234.0
PYH2_k127_6386233_0 Endonuclease I - - - 0.0000000000000000002476 93.0
PYH2_k127_6392682_0 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 349.0
PYH2_k127_63955_0 - - - - 0.000000000000003412 77.0
PYH2_k127_63955_1 - - - - 0.0000000000001123 74.0
PYH2_k127_63955_2 - - - - 0.000008758 48.0
PYH2_k127_63955_3 - - - - 0.0001857 44.0
PYH2_k127_63955_4 Protein of unknown function (DUF2647) - - - 0.0005621 42.0
PYH2_k127_6408441_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
PYH2_k127_6408441_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 365.0
PYH2_k127_6408441_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000001228 223.0
PYH2_k127_6408441_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000692 170.0
PYH2_k127_6408441_4 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000001001 149.0
PYH2_k127_6408441_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000007015 83.0
PYH2_k127_6416820_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 291.0
PYH2_k127_6416820_1 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000000001566 172.0
PYH2_k127_6418019_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 2.794e-205 649.0
PYH2_k127_6418019_1 calcium proton exchanger K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002455 262.0
PYH2_k127_6418019_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000004465 203.0
PYH2_k127_6460829_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007376 267.0
PYH2_k127_6460829_1 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000007682 124.0
PYH2_k127_6548463_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 558.0
PYH2_k127_6548463_1 FAD dependent oxidoreductase K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 527.0
PYH2_k127_6548463_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
PYH2_k127_6548463_3 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
PYH2_k127_6548463_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000001282 185.0
PYH2_k127_6548463_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000001036 177.0
PYH2_k127_6548463_6 Histidine kinase-like ATPases K04079 - - 0.0000000234 66.0
PYH2_k127_6548463_7 Short C-terminal domain K08982 - - 0.00001003 50.0
PYH2_k127_6548463_8 MerR family regulatory protein - - - 0.000255 47.0
PYH2_k127_6549631_0 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
PYH2_k127_6556918_0 Protein of unknown function (DUF3383) - - - 0.0000000000000000000000000000000000000000000000000002258 205.0
PYH2_k127_6556918_1 - - - - 0.000000000000000000000000000000000001777 149.0
PYH2_k127_6556918_2 phage tail tape measure protein - - - 0.000000000000001021 91.0
PYH2_k127_6556918_3 Protein of unknown function (DUF3277) - - - 0.0000000000000106 79.0
PYH2_k127_6556918_4 - - - - 0.000003813 58.0
PYH2_k127_6556918_5 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.0003805 51.0
PYH2_k127_6567128_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 582.0
PYH2_k127_6567128_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 543.0
PYH2_k127_6567128_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000006521 258.0
PYH2_k127_6567128_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001246 230.0
PYH2_k127_6567128_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000001897 162.0
PYH2_k127_6567128_5 Putative Fe-S cluster - - - 0.000000000000000000001128 101.0
PYH2_k127_6574740_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 370.0
PYH2_k127_6609511_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007653 269.0
PYH2_k127_6609511_1 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000002241 187.0
PYH2_k127_6628183_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001664 237.0
PYH2_k127_6628183_1 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000003444 126.0
PYH2_k127_663930_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000337 233.0
PYH2_k127_663930_1 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000006291 130.0
PYH2_k127_663930_2 Recombinase zinc beta ribbon domain - - - 0.000000000001366 71.0
PYH2_k127_6667504_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 467.0
PYH2_k127_6667504_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 364.0
PYH2_k127_6667504_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000001063 243.0
PYH2_k127_6667504_3 Enoyl-CoA hydratase/isomerase K15866,K18474 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000009625 210.0
PYH2_k127_6667504_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
PYH2_k127_6667504_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000003136 194.0
PYH2_k127_6667504_6 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000003161 134.0
PYH2_k127_6667504_7 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA - - - 0.0001846 44.0
PYH2_k127_6670970_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000009768 263.0
PYH2_k127_6670970_1 spore germination K03605 - - 0.0000000000000000000000000000000006293 136.0
PYH2_k127_6670970_2 conserved protein (DUF2088) - - - 0.0000000000000000000000000000001301 127.0
PYH2_k127_6685759_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1017.0
PYH2_k127_6685759_1 COG0477 Permeases of the major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000006243 104.0
PYH2_k127_6699701_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000001404 164.0
PYH2_k127_6699701_1 Cupin domain - - - 0.00000000000001197 79.0
PYH2_k127_6710892_0 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.00000000003684 66.0
PYH2_k127_6710892_1 Domain of unknown function (DUF4382) - - - 0.000002408 53.0
PYH2_k127_6722226_0 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
PYH2_k127_6722226_1 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000000002701 218.0
PYH2_k127_6722807_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 534.0
PYH2_k127_6722807_1 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000003651 124.0
PYH2_k127_6725679_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 548.0
PYH2_k127_6725679_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 455.0
PYH2_k127_6725679_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 250.0
PYH2_k127_6725679_3 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000000000001193 96.0
PYH2_k127_6725679_4 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000002198 85.0
PYH2_k127_6737320_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 437.0
PYH2_k127_6737320_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 318.0
PYH2_k127_6737320_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000018 171.0
PYH2_k127_6737320_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000008532 63.0
PYH2_k127_6740556_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000008888 181.0
PYH2_k127_6740556_1 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit - - - 0.0000006516 51.0
PYH2_k127_6740556_2 Transmembrane secretion effector - - - 0.000002556 55.0
PYH2_k127_6744416_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.836e-270 850.0
PYH2_k127_6744416_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000873 145.0
PYH2_k127_6744416_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000001566 135.0
PYH2_k127_6749394_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 607.0
PYH2_k127_6749394_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 286.0
PYH2_k127_6749394_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH2_k127_6749394_3 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000002232 128.0
PYH2_k127_6749394_4 - - - - 0.0000000000000000611 81.0
PYH2_k127_6765644_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.886e-292 903.0
PYH2_k127_6765644_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001153 251.0
PYH2_k127_6768534_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 505.0
PYH2_k127_6768534_1 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 391.0
PYH2_k127_6768534_2 PQ loop repeat K15383 - - 0.00000000000002526 75.0
PYH2_k127_679164_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 539.0
PYH2_k127_679164_1 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000002574 238.0
PYH2_k127_679164_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000001018 97.0
PYH2_k127_679164_3 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000000002669 65.0
PYH2_k127_679164_4 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.0001764 46.0
PYH2_k127_679390_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000001649 225.0
PYH2_k127_679390_1 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000005928 208.0
PYH2_k127_6795592_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 407.0
PYH2_k127_6795592_1 PspC domain K03973 - - 0.000000000008587 68.0
PYH2_k127_684003_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000434 216.0
PYH2_k127_684003_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000369 172.0
PYH2_k127_684003_2 nitrite transmembrane transporter activity K02575,K10850 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000908 76.0
PYH2_k127_6845702_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1247.0
PYH2_k127_6845702_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
PYH2_k127_6845702_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001007 203.0
PYH2_k127_6845702_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 0.000000000000000000000000000001305 125.0
PYH2_k127_6845702_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00012 49.0
PYH2_k127_6858413_0 Acetone carboxylase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000004109 200.0
PYH2_k127_6858413_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000001662 188.0
PYH2_k127_6858413_2 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474,K10854 - 3.5.2.14,6.4.1.6 0.00000000000000000000000001185 116.0
PYH2_k127_6922345_0 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000001175 176.0
PYH2_k127_6922345_1 Universal stress protein K06149 - - 0.00000000000000004905 82.0
PYH2_k127_6922345_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00001512 48.0
PYH2_k127_6925930_0 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000009781 71.0
PYH2_k127_6938667_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 625.0
PYH2_k127_6938667_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000605 281.0
PYH2_k127_6938667_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000002138 235.0
PYH2_k127_6938667_3 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000003534 223.0
PYH2_k127_694673_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.488e-277 868.0
PYH2_k127_694673_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000005412 237.0
PYH2_k127_694673_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000008395 233.0
PYH2_k127_694673_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000325 197.0
PYH2_k127_694673_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000001067 158.0
PYH2_k127_694673_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000003875 148.0
PYH2_k127_6951498_0 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
PYH2_k127_6951498_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000008686 186.0
PYH2_k127_6951498_2 - - - - 0.0000000000000001641 79.0
PYH2_k127_6958591_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 382.0
PYH2_k127_6958591_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000001984 151.0
PYH2_k127_6958591_2 acid phosphatase activity - - - 0.000000000000000000000005495 114.0
PYH2_k127_6958591_3 META domain protein - - - 0.00000000003993 76.0
PYH2_k127_6973431_0 RNase_H superfamily - - - 0.00000000000000000000000427 105.0
PYH2_k127_6973431_1 Protein of unknown function (DUF2612) - - - 0.0000000002168 68.0
PYH2_k127_6973431_3 Portal protein - - - 0.000005824 57.0
PYH2_k127_697538_0 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
PYH2_k127_697538_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000007555 246.0
PYH2_k127_697538_2 glutaredoxin-like protein, YruB-family - - - 0.000000000000000000238 88.0
PYH2_k127_6981931_0 PFAM Isochorismatase K09020 - 3.5.1.110 0.000000000000000000000000000009507 126.0
PYH2_k127_6981931_1 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000001279 105.0
PYH2_k127_6981931_2 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K07469 - 1.2.99.7 0.0000000000000266 73.0
PYH2_k127_6981931_3 Hemerythrin HHE cation binding domain K09155 - - 0.00005647 50.0
PYH2_k127_7029468_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 386.0
PYH2_k127_7029468_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
PYH2_k127_7029468_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000001155 156.0
PYH2_k127_7029468_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000008222 130.0
PYH2_k127_7029468_4 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.000000000000000000000000000002153 123.0
PYH2_k127_7029779_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000001026 190.0
PYH2_k127_7029779_1 PQQ enzyme repeat - - - 0.0001586 53.0
PYH2_k127_7029784_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000002031 229.0
PYH2_k127_7029784_1 cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000001403 215.0
PYH2_k127_7029784_2 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000121 110.0
PYH2_k127_7029784_3 Serine aminopeptidase, S33 K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.0000000000000000000001115 100.0
PYH2_k127_7031491_0 Conserved carboxylase domain K01960 - 6.4.1.1 8.195e-242 759.0
PYH2_k127_7031491_1 Biotin carboxylase C-terminal domain - - - 4.737e-228 715.0
PYH2_k127_7031491_2 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007753 268.0
PYH2_k127_7031491_3 Phosphatidylethanolamine-binding protein - - - 0.00002077 52.0
PYH2_k127_7041002_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 450.0
PYH2_k127_7041002_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 424.0
PYH2_k127_7041002_2 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 410.0
PYH2_k127_7041002_3 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 319.0
PYH2_k127_7088850_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 356.0
PYH2_k127_7088850_1 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 297.0
PYH2_k127_7088850_2 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000001207 192.0
PYH2_k127_7088850_3 Protein of unknown function (DUF2905) - - - 0.000000007438 57.0
PYH2_k127_7088850_4 Isochorismatase family - - - 0.000002983 57.0
PYH2_k127_7091822_0 Cytochrome c554 and c-prime - - - 0.000002943 53.0
PYH2_k127_7097282_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 327.0
PYH2_k127_7097282_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 307.0
PYH2_k127_7097282_2 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000001731 233.0
PYH2_k127_7097282_3 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000703 229.0
PYH2_k127_7097282_4 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000003033 169.0
PYH2_k127_7120848_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000001845 228.0
PYH2_k127_7120848_1 Yqey-like protein K09117 - - 0.00000000000000000000000000000001147 132.0
PYH2_k127_7120848_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000002582 105.0
PYH2_k127_7120848_3 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.000000000000003584 75.0
PYH2_k127_7120848_4 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000004509 76.0
PYH2_k127_7126859_0 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.00002874 57.0
PYH2_k127_7128164_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1018.0
PYH2_k127_7128164_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000005218 214.0
PYH2_k127_7141770_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 474.0
PYH2_k127_7141770_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000001423 224.0
PYH2_k127_7160811_0 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 309.0
PYH2_k127_7160811_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
PYH2_k127_7160811_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000007654 158.0
PYH2_k127_7186903_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.212e-300 946.0
PYH2_k127_7186903_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 500.0
PYH2_k127_7186903_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 344.0
PYH2_k127_7186903_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 332.0
PYH2_k127_7186903_4 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002248 280.0
PYH2_k127_7186903_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000001328 248.0
PYH2_k127_7186903_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000007272 245.0
PYH2_k127_7186903_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
PYH2_k127_7186903_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000001705 192.0
PYH2_k127_7186903_9 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 - 1.1.1.267 0.00000000008981 63.0
PYH2_k127_7193452_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 456.0
PYH2_k127_7193452_1 COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - 0.000000000000000000257 93.0
PYH2_k127_7194263_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 437.0
PYH2_k127_7233453_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 573.0
PYH2_k127_7233453_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000001799 161.0
PYH2_k127_7234286_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000008026 202.0
PYH2_k127_7234286_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000002289 156.0
PYH2_k127_7234286_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000002061 144.0
PYH2_k127_7234286_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000001202 138.0
PYH2_k127_7234286_4 - - - - 0.000000000000000000000000000114 117.0
PYH2_k127_7234578_0 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.000000008622 64.0
PYH2_k127_7235691_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.313e-239 749.0
PYH2_k127_7235691_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000004053 193.0
PYH2_k127_7235691_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000008839 162.0
PYH2_k127_7235691_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000001367 113.0
PYH2_k127_7235691_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000001033 87.0
PYH2_k127_7238173_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.747e-204 644.0
PYH2_k127_7238173_1 Serine/threonine phosphatases, family 2C, catalytic domain K14803,K17499 - 3.1.3.16 0.0000000006754 64.0
PYH2_k127_7238859_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 376.0
PYH2_k127_7238859_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002904 269.0
PYH2_k127_7238859_2 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000002391 176.0
PYH2_k127_7248082_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 396.0
PYH2_k127_7297596_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 595.0
PYH2_k127_7297596_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 323.0
PYH2_k127_7297596_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000004648 80.0
PYH2_k127_7297596_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000005419 66.0
PYH2_k127_7297596_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000001231 235.0
PYH2_k127_7297596_3 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000228 210.0
PYH2_k127_7297596_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000005139 204.0
PYH2_k127_7297596_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000003716 151.0
PYH2_k127_7297596_6 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000002474 151.0
PYH2_k127_7297596_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000003241 137.0
PYH2_k127_7297596_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000008081 134.0
PYH2_k127_7297596_9 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000004616 83.0
PYH2_k127_7299733_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 308.0
PYH2_k127_7342326_0 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001002 289.0
PYH2_k127_7342326_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004095 273.0
PYH2_k127_7342326_2 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 272.0
PYH2_k127_7358873_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 491.0
PYH2_k127_7358873_1 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000005458 74.0
PYH2_k127_7361488_0 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 311.0
PYH2_k127_7361488_1 Acetyltransferase (GNAT) domain - - - 0.00000000000728 66.0
PYH2_k127_7423590_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008719 283.0
PYH2_k127_7423590_1 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005685 256.0
PYH2_k127_7423590_2 peptidase, M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004683 243.0
PYH2_k127_7423590_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000001638 242.0
PYH2_k127_7423590_4 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
PYH2_k127_7423590_5 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000001144 130.0
PYH2_k127_7423590_6 Thioredoxin-like - - - 0.0000000000000000000000000003547 120.0
PYH2_k127_7423590_7 membrane - - - 0.0000002981 59.0
PYH2_k127_7452413_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 587.0
PYH2_k127_7452413_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000004825 106.0
PYH2_k127_7468799_0 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000002925 214.0
PYH2_k127_7468799_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000002137 152.0
PYH2_k127_7468799_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00006045 46.0
PYH2_k127_7494548_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 320.0
PYH2_k127_7494548_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 295.0
PYH2_k127_7494548_2 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000008365 139.0
PYH2_k127_7506237_0 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000006712 159.0
PYH2_k127_7506237_1 Winged helix-turn-helix - - - 0.0000000000000000000000000000000004998 135.0
PYH2_k127_7506237_2 - - - - 0.000000000000000000000005542 105.0
PYH2_k127_7516715_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 555.0
PYH2_k127_7516715_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 286.0
PYH2_k127_7516715_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000003595 258.0
PYH2_k127_7516715_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000001674 210.0
PYH2_k127_7516715_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000004229 103.0
PYH2_k127_7516715_5 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.0008198 50.0
PYH2_k127_7531606_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 368.0
PYH2_k127_7531606_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 340.0
PYH2_k127_7531606_2 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 299.0
PYH2_k127_7531606_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000001005 171.0
PYH2_k127_7531606_4 transcriptional regulator PadR family K10947 - - 0.00000000000000000000000007768 112.0
PYH2_k127_7531606_5 - - - - 0.000000000000000000001007 95.0
PYH2_k127_754476_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 497.0
PYH2_k127_7553700_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.00000000000000000000000000000000000000000000000000000000002765 213.0
PYH2_k127_7553700_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000001173 210.0
PYH2_k127_7553700_2 4Fe-4S dicluster domain - - - 0.00000000000000006683 83.0
PYH2_k127_7556069_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 411.0
PYH2_k127_7556069_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000001004 169.0
PYH2_k127_7556069_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000001087 111.0
PYH2_k127_7556069_3 helix_turn_helix ASNC type K03718 - - 0.0000000000000002949 84.0
PYH2_k127_7585955_0 oxidation-reduction process - - - 2.9e-320 1007.0
PYH2_k127_7585955_1 Phage integrase, N-terminal SAM-like domain - - - 0.0000000009636 63.0
PYH2_k127_7585984_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 513.0
PYH2_k127_7585984_1 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002678 287.0
PYH2_k127_75911_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.771e-219 692.0
PYH2_k127_75911_1 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
PYH2_k127_75911_10 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.00001192 52.0
PYH2_k127_75911_11 ORF located using Blastx - - - 0.0000817 47.0
PYH2_k127_75911_13 COG NOG20805 non supervised orthologous group - - - 0.0003703 43.0
PYH2_k127_75911_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 256.0
PYH2_k127_75911_3 Alpha/beta hydrolase family K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000003988 216.0
PYH2_k127_75911_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000001985 113.0
PYH2_k127_75911_5 COG NOG15344 non supervised orthologous group - - - 0.0000000000000005916 77.0
PYH2_k127_75911_7 Ribulose bisphosphate carboxylase, large chain K01601,K01963 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.1.3.15,4.1.1.39,6.4.1.2 0.000000003151 59.0
PYH2_k127_75911_9 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.0000002214 61.0
PYH2_k127_76441_0 Heat shock 70 kDa protein K04043 - - 1.006e-303 942.0
PYH2_k127_76441_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00183,K00372,K07306,K08352 - 1.8.5.3,1.8.5.5 2.842e-243 773.0
PYH2_k127_76441_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000003772 155.0
PYH2_k127_76441_11 4Fe-4S dicluster domain - - - 0.00000000000000000000000000002161 120.0
PYH2_k127_76441_12 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000001374 98.0
PYH2_k127_76441_13 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000001533 62.0
PYH2_k127_76441_14 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.00001147 49.0
PYH2_k127_76441_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 467.0
PYH2_k127_76441_3 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 457.0
PYH2_k127_76441_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 417.0
PYH2_k127_76441_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 390.0
PYH2_k127_76441_6 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 373.0
PYH2_k127_76441_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000002527 262.0
PYH2_k127_76441_8 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.0000000000000000000000000000000000000000000000000002713 199.0
PYH2_k127_76441_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000002677 192.0
PYH2_k127_7679670_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000001458 225.0
PYH2_k127_7679670_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
PYH2_k127_7688797_0 domain protein - - - 0.0000000000000000000000000000000000000000000006197 182.0
PYH2_k127_7692818_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 620.0
PYH2_k127_7692818_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 397.0
PYH2_k127_7692818_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 353.0
PYH2_k127_7692818_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 275.0
PYH2_k127_7692818_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000007244 189.0
PYH2_k127_7692818_5 GAF domain - - - 0.0000000000000000000000000000000000000000000000007997 190.0
PYH2_k127_7692818_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000002296 118.0
PYH2_k127_7692818_7 PFAM response regulator receiver - - - 0.0000000000000000000004586 100.0
PYH2_k127_7692818_8 PFAM Cyclic nucleotide-binding domain - - - 0.00000002877 61.0
PYH2_k127_7701542_0 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 510.0
PYH2_k127_7701542_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 471.0
PYH2_k127_7701542_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
PYH2_k127_7701542_3 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000001726 174.0
PYH2_k127_7701542_4 TIGRFAM type I restriction system adenine methylase (hsdM) K03427 - 2.1.1.72 0.00000000119 60.0
PYH2_k127_7708455_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.105e-287 909.0
PYH2_k127_7708455_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000001918 236.0
PYH2_k127_7714459_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 584.0
PYH2_k127_7714459_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 447.0
PYH2_k127_7714459_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0008731 44.0
PYH2_k127_7729031_0 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 557.0
PYH2_k127_7729031_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 346.0
PYH2_k127_7729031_2 Class ii aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000002283 201.0
PYH2_k127_7729031_3 ligase activity K01474 - 3.5.2.14 0.00000000000000000000000826 117.0
PYH2_k127_7729031_4 - - - - 0.00000000000000002774 87.0
PYH2_k127_7752998_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 340.0
PYH2_k127_7752998_1 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000009588 121.0
PYH2_k127_7752998_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000006823 71.0
PYH2_k127_7752998_3 succinate dehydrogenase activity K00242,K00246 - - 0.000001405 55.0
PYH2_k127_7758157_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 343.0
PYH2_k127_7758157_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 305.0
PYH2_k127_7758282_0 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000001449 217.0
PYH2_k127_7758282_1 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.000000000000000000000009081 117.0
PYH2_k127_7758282_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000001127 74.0
PYH2_k127_7760894_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 445.0
PYH2_k127_7760894_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 337.0
PYH2_k127_7760894_2 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677,K03779 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 336.0
PYH2_k127_7760894_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
PYH2_k127_7760894_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 320.0
PYH2_k127_77980_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.2e-307 969.0
PYH2_k127_7798884_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000325 228.0
PYH2_k127_7798884_1 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000001721 185.0
PYH2_k127_7801247_0 cellulose binding - - - 0.00000000000000000000003485 109.0
PYH2_k127_7812173_0 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000000002998 82.0
PYH2_k127_7828829_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 514.0
PYH2_k127_7828829_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 484.0
PYH2_k127_7828829_2 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 274.0
PYH2_k127_7828829_3 ABC-2 family transporter protein - - - 0.0000000000000000000000005288 111.0
PYH2_k127_7828829_4 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000001339 59.0
PYH2_k127_783386_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 373.0
PYH2_k127_7858974_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003237 219.0
PYH2_k127_7858974_1 nodulation - - - 0.0000000000000000000000000000000000000000000000000000009441 207.0
PYH2_k127_7858974_2 membrane K00389 - - 0.00000000000002056 76.0
PYH2_k127_7860405_0 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 321.0
PYH2_k127_7860405_1 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 251.0
PYH2_k127_7866890_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
PYH2_k127_7866890_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001567 81.0
PYH2_k127_7866890_2 Oxidoreductase family, C-terminal alpha/beta domain K19181 - 1.1.1.292 0.00003664 51.0
PYH2_k127_7867432_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 579.0
PYH2_k127_7867432_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000001273 172.0
PYH2_k127_7867432_2 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000006465 171.0
PYH2_k127_7892986_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004015 240.0
PYH2_k127_7893044_0 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 302.0
PYH2_k127_7893044_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000000001367 92.0
PYH2_k127_7893044_2 - - - - 0.000000000000000001078 85.0
PYH2_k127_7914290_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 1.958e-222 702.0
PYH2_k127_7923880_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1079.0
PYH2_k127_7923880_1 Pfam Major Facilitator Superfamily K08223 - - 0.00000000000001253 83.0
PYH2_k127_7974033_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 394.0
PYH2_k127_7974033_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 332.0
PYH2_k127_7974033_2 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000003089 198.0
PYH2_k127_7974033_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.00000005498 61.0
PYH2_k127_7974033_4 PFAM Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000002143 57.0
PYH2_k127_7983223_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 338.0
PYH2_k127_7983223_1 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000009311 198.0
PYH2_k127_7983223_2 Belongs to the sulfur carrier protein TusA family - - - 0.00000001373 58.0
PYH2_k127_7991917_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 588.0
PYH2_k127_7991917_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000002248 94.0
PYH2_k127_7994710_0 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000476 279.0
PYH2_k127_7994710_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007757 262.0
PYH2_k127_7996876_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 415.0
PYH2_k127_7996876_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
PYH2_k127_7996876_10 structural constituent of ribosome K02904 - - 0.000000000000002177 79.0
PYH2_k127_7996876_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000002597 53.0
PYH2_k127_7996876_2 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
PYH2_k127_7996876_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008301 248.0
PYH2_k127_7996876_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000003431 205.0
PYH2_k127_7996876_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000004369 184.0
PYH2_k127_7996876_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000001247 149.0
PYH2_k127_7996876_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000003329 138.0
PYH2_k127_7996876_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000227 104.0
PYH2_k127_7996876_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007691 103.0
PYH2_k127_8011278_0 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000005069 129.0
PYH2_k127_8079740_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 384.0
PYH2_k127_809125_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 465.0
PYH2_k127_809125_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000302 177.0
PYH2_k127_809125_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000003135 95.0
PYH2_k127_809125_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000001412 66.0
PYH2_k127_8117467_0 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003854 275.0
PYH2_k127_8117467_1 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000004226 204.0
PYH2_k127_8117467_2 Universal stress protein family - - - 0.000000000000000000000000000000000002466 143.0
PYH2_k127_8117467_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000001827 96.0
PYH2_k127_814035_0 cellulose binding - - - 0.00000000000000000000000000000001439 138.0
PYH2_k127_814035_1 - - - - 0.000000000000000000000000000001381 131.0
PYH2_k127_8147514_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 317.0
PYH2_k127_8147514_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
PYH2_k127_8195333_0 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000009591 259.0
PYH2_k127_8195333_1 acetyltransferase - - - 0.00000000007741 65.0
PYH2_k127_8209765_0 GMC oxidoreductase K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 439.0
PYH2_k127_8209765_1 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000003244 141.0
PYH2_k127_8209765_2 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000000000002819 130.0
PYH2_k127_8209765_3 PFAM Secreted repeat of - - - 0.000000000000000000000001553 118.0
PYH2_k127_8209765_4 Cytochrome c K02030 - - 0.0000000000000000000009963 100.0
PYH2_k127_8209765_5 - K06039 - - 0.0000000000005766 71.0
PYH2_k127_821913_0 PFAM PEBP family protein K06910 - - 0.00000000006615 72.0
PYH2_k127_821913_1 Phosphatidylethanolamine-binding protein - - - 0.00000000255 61.0
PYH2_k127_8220233_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 456.0
PYH2_k127_8220233_1 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 351.0
PYH2_k127_8220233_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0003328 44.0
PYH2_k127_8284035_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 327.0
PYH2_k127_8284035_1 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000001313 123.0
PYH2_k127_8284035_2 Methyltransferase type 11 - - - 0.00000000000000008009 87.0
PYH2_k127_8290111_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 306.0
PYH2_k127_8290111_1 Psort location CytoplasmicMembrane, score K01992 - - 0.0000000000000000000000000000000000002183 147.0
PYH2_k127_8312826_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000007851 207.0
PYH2_k127_8320987_0 - - - - 0.000000000000000000000000000000000002173 158.0
PYH2_k127_8330756_0 - - - - 0.00000000000000008039 96.0
PYH2_k127_8354051_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007013 256.0
PYH2_k127_8354051_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000002717 66.0
PYH2_k127_8361523_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 290.0
PYH2_k127_8361523_1 L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.000000008318 59.0
PYH2_k127_8363112_0 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.0000000000000000000000000000000000000000000000000000000000000009692 231.0
PYH2_k127_837761_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 509.0
PYH2_k127_837761_1 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000003275 174.0
PYH2_k127_8393059_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000005465 165.0
PYH2_k127_842986_0 HMGL-like K02594 - 2.3.3.14 1.358e-199 629.0
PYH2_k127_842986_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 512.0
PYH2_k127_842986_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000003019 238.0
PYH2_k127_8437277_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 7.611e-236 738.0
PYH2_k127_8437277_1 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000005619 168.0
PYH2_k127_8439534_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.718e-308 955.0
PYH2_k127_8447552_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 305.0
PYH2_k127_8459721_0 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
PYH2_k127_8459721_1 Protein of unknown function (DUF664) - - - 0.0000000000000001841 87.0
PYH2_k127_84988_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 334.0
PYH2_k127_84988_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000001784 176.0
PYH2_k127_8518655_0 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001628 245.0
PYH2_k127_8518655_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000001506 155.0
PYH2_k127_8535731_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
PYH2_k127_8535731_1 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 263.0
PYH2_k127_8535731_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
PYH2_k127_8535731_3 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000003031 200.0
PYH2_k127_8535731_4 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000001895 130.0
PYH2_k127_8593212_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 461.0
PYH2_k127_8593212_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 371.0
PYH2_k127_8593212_2 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000002555 183.0
PYH2_k127_8593212_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000001131 56.0
PYH2_k127_8677562_0 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 432.0
PYH2_k127_8677562_1 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000171 149.0
PYH2_k127_8677562_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000137 131.0
PYH2_k127_8677562_3 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.0000000002233 61.0
PYH2_k127_8716668_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 401.0
PYH2_k127_8716668_1 HTH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
PYH2_k127_8716668_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
PYH2_k127_8716668_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002433 217.0
PYH2_k127_8716668_4 transposase activity - - - 0.0000000000000000000000000000006559 123.0
PYH2_k127_8728122_0 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000001391 242.0
PYH2_k127_8728122_1 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000004728 220.0
PYH2_k127_8728122_2 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000001644 132.0
PYH2_k127_8731752_0 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002314 265.0
PYH2_k127_8731752_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000001162 225.0
PYH2_k127_8731752_2 4Fe-4S dicluster domain K03389,K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000003358 182.0
PYH2_k127_8731752_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000002623 118.0
PYH2_k127_8731752_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000002547 103.0
PYH2_k127_8731752_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000003841 94.0
PYH2_k127_8731752_6 Regulatory protein, FmdB family - - - 0.000001464 51.0
PYH2_k127_876108_0 ABC transporter, transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 559.0
PYH2_k127_876108_1 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 545.0
PYH2_k127_876108_2 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 496.0
PYH2_k127_876108_3 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 391.0
PYH2_k127_876108_4 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 303.0
PYH2_k127_876108_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003715 276.0
PYH2_k127_876108_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000006945 172.0
PYH2_k127_876108_7 Transcriptional regulator PadR-like family - - - 0.0000000000000000000001696 103.0
PYH2_k127_876108_8 Protein of unknown function (DUF664) - - - 0.0000000000000001477 87.0
PYH2_k127_876108_9 Domain of unknown function (DUF4129) - - - 0.00000000008676 72.0
PYH2_k127_8781990_0 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 510.0
PYH2_k127_8781990_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000004533 79.0
PYH2_k127_8781990_2 Helix-turn-helix domain - - - 0.000002251 55.0
PYH2_k127_8792241_0 ABC transporter substrate-binding protein K02035 - - 0.000005756 55.0
PYH2_k127_8792241_1 Domain of unknown function (DUF4382) - - - 0.000007211 52.0
PYH2_k127_8829039_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002098 262.0
PYH2_k127_8835835_0 Pfam:Kce K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
PYH2_k127_8835835_1 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 308.0
PYH2_k127_8846088_0 dolichyl monophosphate biosynthetic process - - - 0.00000001503 63.0
PYH2_k127_8873709_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000001158 151.0
PYH2_k127_8873709_1 - - - - 0.000002657 52.0
PYH2_k127_8885776_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 431.0
PYH2_k127_8885776_1 2-methylcitrate dehydratase activity K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000009183 191.0
PYH2_k127_8885776_2 metal-dependent hydrolase of the TIM-barrel fold K07045,K22213 - 4.1.1.52 0.000000000000000000004985 101.0
PYH2_k127_8885776_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0009222 42.0
PYH2_k127_888706_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 345.0
PYH2_k127_888706_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000003114 130.0
PYH2_k127_8889760_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.806e-201 637.0
PYH2_k127_8889760_1 B12 binding domain - - - 0.0000004544 55.0
PYH2_k127_8895833_0 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 518.0
PYH2_k127_8895833_1 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000003275 161.0
PYH2_k127_8899648_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 359.0
PYH2_k127_8899648_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
PYH2_k127_8899648_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000004954 177.0
PYH2_k127_8899648_3 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000009164 142.0
PYH2_k127_8899648_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000005463 141.0
PYH2_k127_8899648_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002723 111.0
PYH2_k127_8903854_0 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 291.0
PYH2_k127_8903854_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000005329 209.0
PYH2_k127_8903854_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000108 206.0
PYH2_k127_8903854_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000005053 102.0
PYH2_k127_8903854_4 3-hydroxyacyl-CoA dehydrogenase K00074,K15016,K15019 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17 0.000000000000000000512 90.0
PYH2_k127_8903854_5 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000002782 83.0
PYH2_k127_8904394_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000002804 218.0
PYH2_k127_8904394_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000002234 189.0
PYH2_k127_8904394_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000003657 118.0
PYH2_k127_8908651_0 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 293.0
PYH2_k127_8908651_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005207 261.0
PYH2_k127_8956846_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 574.0
PYH2_k127_8956846_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 365.0
PYH2_k127_8956846_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 356.0
PYH2_k127_8956846_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 334.0
PYH2_k127_8956846_4 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
PYH2_k127_8956846_5 YHYH protein - - - 0.0000000000000000000000000007356 121.0
PYH2_k127_8956846_6 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000008052 116.0
PYH2_k127_8956846_7 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000001312 75.0
PYH2_k127_8971176_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008558 269.0
PYH2_k127_8971176_1 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000002604 200.0
PYH2_k127_8971176_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000001971 132.0
PYH2_k127_8971176_3 Belongs to the UPF0434 family - - - 0.0000000000000003401 80.0
PYH2_k127_8983071_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000001309 232.0
PYH2_k127_8983071_1 Subtilase family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000001138 208.0
PYH2_k127_8988458_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000001898 217.0
PYH2_k127_8988458_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000003151 132.0
PYH2_k127_9030615_0 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000008807 186.0
PYH2_k127_9030615_1 cyclase family - - - 0.000000000000000000000000000008112 123.0
PYH2_k127_9064993_0 PFAM type II and III secretion system protein K02280 - - 0.0000000000000000000000000000000000000004133 168.0
PYH2_k127_9064993_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000007514 82.0
PYH2_k127_9064993_2 energy transducer activity K03832 - - 0.000002391 60.0
PYH2_k127_9065439_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 425.0
PYH2_k127_9085295_0 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000916 150.0
PYH2_k127_9089362_0 Telomere recombination K04656 - - 1.879e-271 856.0
PYH2_k127_9089362_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 586.0
PYH2_k127_9089362_10 DegV family - - - 0.000000000000000000000000000000003001 139.0
PYH2_k127_9089362_11 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000001532 119.0
PYH2_k127_9089362_12 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000001147 114.0
PYH2_k127_9089362_13 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000003259 111.0
PYH2_k127_9089362_14 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000003444 97.0
PYH2_k127_9089362_15 hydrogenase assembly chaperone HypC HupF K04653 - - 0.000000000000000004345 85.0
PYH2_k127_9089362_16 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.0000000000000363 75.0
PYH2_k127_9089362_2 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 467.0
PYH2_k127_9089362_3 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 436.0
PYH2_k127_9089362_4 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 402.0
PYH2_k127_9089362_5 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 363.0
PYH2_k127_9089362_6 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 301.0
PYH2_k127_9089362_7 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 282.0
PYH2_k127_9089362_8 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000355 250.0
PYH2_k127_9089362_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000002376 137.0
PYH2_k127_9091342_0 leucine- rich repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 361.0
PYH2_k127_9091342_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000001102 171.0
PYH2_k127_912781_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.321e-247 771.0
PYH2_k127_912781_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.772e-245 768.0
PYH2_k127_912781_10 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
PYH2_k127_912781_11 periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 291.0
PYH2_k127_912781_12 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 285.0
PYH2_k127_912781_13 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000493 242.0
PYH2_k127_912781_14 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000001565 192.0
PYH2_k127_912781_15 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000007054 170.0
PYH2_k127_912781_16 Cupin domain - - - 0.000000000000000000000000000000000007631 139.0
PYH2_k127_912781_17 - - - - 0.0000000000000000000000003291 106.0
PYH2_k127_912781_2 Ftsk_gamma K03466 - - 3.274e-234 746.0
PYH2_k127_912781_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 4.961e-227 728.0
PYH2_k127_912781_4 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 3.769e-208 660.0
PYH2_k127_912781_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 413.0
PYH2_k127_912781_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 377.0
PYH2_k127_912781_7 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 375.0
PYH2_k127_912781_8 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 369.0
PYH2_k127_912781_9 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 362.0
PYH2_k127_9134635_0 Phage Tail Collar Domain - - - 0.0000000000000000000003241 101.0
PYH2_k127_9134635_1 - - - - 0.0008092 49.0
PYH2_k127_9162098_0 tRNA-splicing ligase RtcB K14415 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 514.0
PYH2_k127_9162098_1 - - - - 0.00000000001113 70.0
PYH2_k127_9162098_2 Protein of unknown function DUF45 K07043 - - 0.00000005209 63.0
PYH2_k127_9181927_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 547.0
PYH2_k127_9181927_1 PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000009598 129.0
PYH2_k127_9221688_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 289.0
PYH2_k127_9221688_1 Major Facilitator Superfamily - - - 0.00008658 49.0
PYH2_k127_9223927_0 amine dehydrogenase activity - - - 0.0000000000000000007254 98.0
PYH2_k127_9231815_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 433.0
PYH2_k127_9231815_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000001804 244.0
PYH2_k127_9231815_2 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519,K11178 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001896 214.0
PYH2_k127_9231815_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000002997 102.0
PYH2_k127_9231815_4 carbon monoxide dehydrogenase small subunit K03518 - 1.2.5.3 0.0000000000000000004558 89.0
PYH2_k127_9244232_0 efflux protein, MATE family - - - 0.00000000000000000000000000000000000000000000000003575 192.0
PYH2_k127_9244232_1 amidohydrolase K07045,K14333 - 4.1.1.46 0.0000000000000000000000000000000000001807 147.0
PYH2_k127_9244232_2 efflux protein, MATE family - - - 0.00000000002263 70.0
PYH2_k127_9251220_0 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 396.0
PYH2_k127_9251220_1 peptidyl-tyrosine sulfation - - - 0.000003062 52.0
PYH2_k127_9310855_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1134.0
PYH2_k127_9310855_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 464.0
PYH2_k127_9311373_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 488.0
PYH2_k127_9311373_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000001773 126.0
PYH2_k127_9311373_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.00000003705 60.0
PYH2_k127_9312462_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000002147 229.0
PYH2_k127_9312462_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000001237 173.0
PYH2_k127_938732_0 Acetyltransferase, gnat family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000749 263.0
PYH2_k127_938732_1 PFAM Abortive infection protein - - - 0.000000000000000000001088 99.0
PYH2_k127_938732_2 Parallel beta-helix repeats - - - 0.0000000002319 65.0
PYH2_k127_95095_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000005407 138.0
PYH2_k127_95095_1 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000004007 119.0
PYH2_k127_959734_0 regulator of chromosome condensation, RCC1 - - - 0.000000000000001786 91.0