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Overview

ID MAG03182
Name PYH2_bin.25
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order UBA7656
Family UBA7656
Genus JADGNW01
Species
Assembly information
Completeness (%) 99.3
Contamination (%) 0.16
GC content (%) 58.0
N50 (bp) 33,908
Genome size (bp) 6,178,522

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4711

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1128629_0 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 543.0
PYH2_k127_1128629_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 540.0
PYH2_k127_1128629_10 Lipocalin-like domain - - - 0.000000000001793 72.0
PYH2_k127_1128629_11 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000001328 65.0
PYH2_k127_1128629_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000001273 55.0
PYH2_k127_1128629_2 amino acid transport K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 435.0
PYH2_k127_1128629_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 337.0
PYH2_k127_1128629_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000008757 182.0
PYH2_k127_1128629_6 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000006229 151.0
PYH2_k127_1128629_7 GYD domain - - - 0.0000000000000000000000000000005019 126.0
PYH2_k127_1128629_8 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000003444 97.0
PYH2_k127_1128629_9 Ankyrin repeats (many copies) - - - 0.000000000000001096 87.0
PYH2_k127_1141668_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.926e-218 691.0
PYH2_k127_1141668_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 9.986e-209 660.0
PYH2_k127_1141668_10 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 269.0
PYH2_k127_1141668_11 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000001049 233.0
PYH2_k127_1141668_12 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000005301 234.0
PYH2_k127_1141668_13 oxidoreductase activity K12511 - - 0.0000000000000000000000000000000000000000000000000000000000003872 228.0
PYH2_k127_1141668_14 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000005946 218.0
PYH2_k127_1141668_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000008191 213.0
PYH2_k127_1141668_16 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000000000000000000000000000000000000001155 207.0
PYH2_k127_1141668_17 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000002588 190.0
PYH2_k127_1141668_18 oxidoreductase activity K12511 - - 0.000000000000000000000000000000000000000000000595 179.0
PYH2_k127_1141668_19 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.000000000000000000000000000000000000000003294 177.0
PYH2_k127_1141668_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.068e-206 655.0
PYH2_k127_1141668_20 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000005895 160.0
PYH2_k127_1141668_21 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000002635 160.0
PYH2_k127_1141668_22 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001118 164.0
PYH2_k127_1141668_23 YjbR - - - 0.0000000000000000000000000000000004425 134.0
PYH2_k127_1141668_24 Methyltransferase domain - - - 0.000000000000000000000000000000001702 139.0
PYH2_k127_1141668_25 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000002214 138.0
PYH2_k127_1141668_26 Protein tyrosine kinase - - - 0.0000000000000000000000000000002704 126.0
PYH2_k127_1141668_27 - - - - 0.0000000000000000000000000000003783 130.0
PYH2_k127_1141668_28 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000915 128.0
PYH2_k127_1141668_3 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 585.0
PYH2_k127_1141668_30 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000002204 111.0
PYH2_k127_1141668_31 - - - - 0.00000000000000000000000561 110.0
PYH2_k127_1141668_32 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000005981 108.0
PYH2_k127_1141668_34 Acetyltransferase (GNAT) domain - - - 0.00000000000000002816 86.0
PYH2_k127_1141668_35 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000003649 82.0
PYH2_k127_1141668_36 DinB family - - - 0.000000000000001179 84.0
PYH2_k127_1141668_37 Protein of unknown function (DUF433) - - - 0.00000000000002116 78.0
PYH2_k127_1141668_38 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001296 74.0
PYH2_k127_1141668_39 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.0000000001067 67.0
PYH2_k127_1141668_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 494.0
PYH2_k127_1141668_40 - - - - 0.00000000252 61.0
PYH2_k127_1141668_41 - - - - 0.000000006646 60.0
PYH2_k127_1141668_42 - - - - 0.00000002141 57.0
PYH2_k127_1141668_44 - - - - 0.00000004872 62.0
PYH2_k127_1141668_45 Dipeptidyl peptidase IV (DPP IV) N-terminal region K03641 - - 0.0000009629 57.0
PYH2_k127_1141668_46 DinB family - - - 0.000002231 52.0
PYH2_k127_1141668_47 Sigma-70 region 2 K03088 - - 0.00001749 48.0
PYH2_k127_1141668_5 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 464.0
PYH2_k127_1141668_6 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 424.0
PYH2_k127_1141668_7 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 297.0
PYH2_k127_1141668_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 297.0
PYH2_k127_1141668_9 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
PYH2_k127_122043_0 Baseplate J-like protein - - - 1.461e-264 835.0
PYH2_k127_122043_1 Phage tail sheath C-terminal domain K06907 - - 1.41e-262 822.0
PYH2_k127_122043_10 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000318 275.0
PYH2_k127_122043_11 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
PYH2_k127_122043_12 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
PYH2_k127_122043_13 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
PYH2_k127_122043_14 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000004488 224.0
PYH2_k127_122043_15 - - - - 0.00000000000000000000000000000000000000000000000000212 194.0
PYH2_k127_122043_16 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000003303 188.0
PYH2_k127_122043_17 GPW gp25 family protein K06903 - - 0.0000000000000000000000000000000000000000000000004092 181.0
PYH2_k127_122043_18 - - - - 0.0000003196 57.0
PYH2_k127_122043_2 Phage tail protein (Tail_P2_I) - - - 5.188e-237 767.0
PYH2_k127_122043_3 Phage tail sheath protein subtilisin-like domain - - - 1.169e-209 687.0
PYH2_k127_122043_4 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 462.0
PYH2_k127_122043_5 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 428.0
PYH2_k127_122043_6 protein and some similarities with VgrG protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 392.0
PYH2_k127_122043_7 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 398.0
PYH2_k127_122043_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 398.0
PYH2_k127_122043_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 314.0
PYH2_k127_1233923_0 metallocarboxypeptidase activity K14054 - - 0.0 1238.0
PYH2_k127_1233923_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 451.0
PYH2_k127_1233923_10 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000002724 189.0
PYH2_k127_1233923_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001461 169.0
PYH2_k127_1233923_12 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000002373 159.0
PYH2_k127_1233923_13 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000003926 120.0
PYH2_k127_1233923_14 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000008098 98.0
PYH2_k127_1233923_15 Protein tyrosine kinase K12132 - 2.7.11.1 0.000004706 51.0
PYH2_k127_1233923_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 432.0
PYH2_k127_1233923_3 Peptidase M14, carboxypeptidase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 394.0
PYH2_k127_1233923_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 369.0
PYH2_k127_1233923_5 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 297.0
PYH2_k127_1233923_6 fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000001507 220.0
PYH2_k127_1233923_7 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000005695 201.0
PYH2_k127_1233923_9 - - - - 0.000000000000000000000000000000000000000000000000001369 200.0
PYH2_k127_1271961_0 LVIVD repeat - - - 0.0 1373.0
PYH2_k127_1271961_1 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.0 1024.0
PYH2_k127_1271961_10 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004401 283.0
PYH2_k127_1271961_11 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003627 296.0
PYH2_k127_1271961_12 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
PYH2_k127_1271961_13 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000005646 236.0
PYH2_k127_1271961_14 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000003945 208.0
PYH2_k127_1271961_15 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000173 213.0
PYH2_k127_1271961_16 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000002818 189.0
PYH2_k127_1271961_17 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000000000000000000000000000000000004164 190.0
PYH2_k127_1271961_18 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000001006 186.0
PYH2_k127_1271961_19 FHA domain - - - 0.00000005519 67.0
PYH2_k127_1271961_2 Belongs to the transketolase family K00615 - 2.2.1.1 7.353e-313 970.0
PYH2_k127_1271961_20 PFAM Cytochrome c, bacterial - - - 0.00000006208 62.0
PYH2_k127_1271961_21 anaerobic respiration - - - 0.0000009674 60.0
PYH2_k127_1271961_22 denitrification pathway - - - 0.00009693 53.0
PYH2_k127_1271961_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 1.986e-199 632.0
PYH2_k127_1271961_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 604.0
PYH2_k127_1271961_5 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 592.0
PYH2_k127_1271961_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 514.0
PYH2_k127_1271961_7 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 470.0
PYH2_k127_1271961_8 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 332.0
PYH2_k127_1271961_9 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 311.0
PYH2_k127_1272930_0 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 568.0
PYH2_k127_1272930_1 Aldo Keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 487.0
PYH2_k127_1272930_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000007462 117.0
PYH2_k127_1272930_11 DinB family - - - 0.0000000000000000000000000007803 119.0
PYH2_k127_1272930_12 Zn peptidase - - - 0.00000002774 63.0
PYH2_k127_1272930_13 Clan AA aspartic protease - - - 0.00000008098 59.0
PYH2_k127_1272930_14 - - - - 0.00012 49.0
PYH2_k127_1272930_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 424.0
PYH2_k127_1272930_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 332.0
PYH2_k127_1272930_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002021 269.0
PYH2_k127_1272930_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003966 230.0
PYH2_k127_1272930_6 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000006388 207.0
PYH2_k127_1272930_7 zinc ion binding - - - 0.00000000000000000000000000000000000000000000002305 194.0
PYH2_k127_1272930_8 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000003362 164.0
PYH2_k127_1272930_9 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000008568 131.0
PYH2_k127_1285420_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 7.9e-239 757.0
PYH2_k127_1285420_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.433e-221 702.0
PYH2_k127_1285420_10 Domain of unknown function (DUF1287) K09974 - - 0.000004199 50.0
PYH2_k127_1285420_11 - - - - 0.000706 49.0
PYH2_k127_1285420_12 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0009785 50.0
PYH2_k127_1285420_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 429.0
PYH2_k127_1285420_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 392.0
PYH2_k127_1285420_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 308.0
PYH2_k127_1285420_5 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003973 283.0
PYH2_k127_1285420_6 Forkhead associated domain - - - 0.000000000000000000000000000004572 136.0
PYH2_k127_1285420_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000007216 86.0
PYH2_k127_1285420_8 PFAM glutaredoxin K18917 - 1.20.4.3 0.000000000009931 68.0
PYH2_k127_1285420_9 - - - - 0.0000003784 63.0
PYH2_k127_1319218_0 Tetratricopeptide repeat - - - 5.926e-202 647.0
PYH2_k127_1319218_1 PFAM glycoside hydrolase, family 37 K01194 - 3.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 611.0
PYH2_k127_1319218_2 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.000000000000000000000000000000000000000000000000000268 188.0
PYH2_k127_1319218_3 AhpC/TSA family - - - 0.000000000000000000000000000000000211 139.0
PYH2_k127_1319218_4 beta-1,4-mannooligosaccharide phosphorylase K21065 - 3.2.1.197 0.00000000000000001521 88.0
PYH2_k127_1328121_0 Radical SAM - - - 0.0 1204.0
PYH2_k127_1328121_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 4.724e-224 709.0
PYH2_k127_1328121_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005001 262.0
PYH2_k127_1328121_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000001409 215.0
PYH2_k127_1328121_12 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000003474 207.0
PYH2_k127_1328121_13 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000002044 189.0
PYH2_k127_1328121_14 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000000007865 181.0
PYH2_k127_1328121_15 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000002042 183.0
PYH2_k127_1328121_16 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000002441 117.0
PYH2_k127_1328121_17 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.00000000000000000000003132 107.0
PYH2_k127_1328121_18 PFAM thioesterase superfamily K02614 - - 0.00000000000000004304 88.0
PYH2_k127_1328121_19 DinB family - - - 0.00000000000001249 80.0
PYH2_k127_1328121_2 (ABC) transporter K06147,K18890 - - 1.39e-200 642.0
PYH2_k127_1328121_20 - - - - 0.000001105 51.0
PYH2_k127_1328121_3 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 592.0
PYH2_k127_1328121_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 494.0
PYH2_k127_1328121_5 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 469.0
PYH2_k127_1328121_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 395.0
PYH2_k127_1328121_7 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 380.0
PYH2_k127_1328121_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
PYH2_k127_1328121_9 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 333.0
PYH2_k127_1380082_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 581.0
PYH2_k127_1380082_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 536.0
PYH2_k127_1404789_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 510.0
PYH2_k127_1404789_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 485.0
PYH2_k127_1404789_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 333.0
PYH2_k127_1404789_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000002938 94.0
PYH2_k127_1404789_4 HEAT repeat-containing protein - - - 0.000000000001524 81.0
PYH2_k127_1404789_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000567 66.0
PYH2_k127_1414593_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.735e-236 748.0
PYH2_k127_1414593_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000002511 64.0
PYH2_k127_1414593_2 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000003214 61.0
PYH2_k127_1430506_0 Alpha-2-Macroglobulin K06894 - - 9.823e-309 1005.0
PYH2_k127_1430506_1 ABC transporter K06020 - 3.6.3.25 7.715e-305 940.0
PYH2_k127_1430506_10 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.00000000000000000000000000000000000003197 158.0
PYH2_k127_1430506_11 DinB superfamily - - - 0.0000000000000000000000000000000000001131 147.0
PYH2_k127_1430506_13 - - - - 0.000000000000000000002009 101.0
PYH2_k127_1430506_14 penicillin-binding protein - - - 0.0000000000000000006018 103.0
PYH2_k127_1430506_2 PFAM peptidase - - - 1.212e-220 699.0
PYH2_k127_1430506_3 (ABC) transporter K06147,K06148 - - 5.987e-213 680.0
PYH2_k127_1430506_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 421.0
PYH2_k127_1430506_5 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 417.0
PYH2_k127_1430506_6 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 374.0
PYH2_k127_1430506_7 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000003087 220.0
PYH2_k127_1430506_8 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000481 217.0
PYH2_k127_1430506_9 Protein of unknown function (DUF1175) K09934 - - 0.00000000000000000000000000000000000000000000000000001245 198.0
PYH2_k127_1452350_0 Peptidase S46 - - - 1.507e-230 734.0
PYH2_k127_1452350_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 5.442e-226 728.0
PYH2_k127_1452350_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 9.711e-204 656.0
PYH2_k127_1452350_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 612.0
PYH2_k127_1452350_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 417.0
PYH2_k127_1452350_5 Polyprenyl synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 329.0
PYH2_k127_1452350_6 TIGRFAM geranylgeranyl reductase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000006621 178.0
PYH2_k127_1452350_7 peptidyl-tyrosine sulfation - - - 0.000000003056 60.0
PYH2_k127_1459619_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 469.0
PYH2_k127_1459619_1 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 358.0
PYH2_k127_1459619_10 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000006012 167.0
PYH2_k127_1459619_11 Histidine kinase - - - 0.000000000000000000000000000000000000000004184 179.0
PYH2_k127_1459619_12 sister chromatid segregation - - - 0.00000000000000000000000000000000000005859 162.0
PYH2_k127_1459619_13 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000002486 132.0
PYH2_k127_1459619_14 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000005498 120.0
PYH2_k127_1459619_15 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000007816 124.0
PYH2_k127_1459619_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000009875 111.0
PYH2_k127_1459619_17 Tetratricopeptide repeat - - - 0.00000002612 66.0
PYH2_k127_1459619_2 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 333.0
PYH2_k127_1459619_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 310.0
PYH2_k127_1459619_4 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 299.0
PYH2_k127_1459619_5 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 276.0
PYH2_k127_1459619_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002003 263.0
PYH2_k127_1459619_7 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000005024 251.0
PYH2_k127_1459619_8 Lipase (class 3) - - - 0.00000000000000000000000000000000000000000000000000001572 200.0
PYH2_k127_1459619_9 - - - - 0.000000000000000000000000000000000000000000000003074 180.0
PYH2_k127_1508513_0 radical SAM domain protein - - - 3.751e-285 886.0
PYH2_k127_1508513_1 Carboxyl transferase domain - - - 2.667e-226 715.0
PYH2_k127_1508513_10 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 433.0
PYH2_k127_1508513_11 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 409.0
PYH2_k127_1508513_12 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 412.0
PYH2_k127_1508513_13 amine oxidase K00276 - 1.4.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 409.0
PYH2_k127_1508513_14 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 373.0
PYH2_k127_1508513_15 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
PYH2_k127_1508513_16 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 364.0
PYH2_k127_1508513_17 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 317.0
PYH2_k127_1508513_18 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 298.0
PYH2_k127_1508513_19 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002163 289.0
PYH2_k127_1508513_2 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 593.0
PYH2_k127_1508513_20 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000175 287.0
PYH2_k127_1508513_21 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003597 263.0
PYH2_k127_1508513_22 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000001737 220.0
PYH2_k127_1508513_23 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000003379 195.0
PYH2_k127_1508513_24 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000001037 185.0
PYH2_k127_1508513_25 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000002765 191.0
PYH2_k127_1508513_26 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000004093 161.0
PYH2_k127_1508513_27 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000008845 137.0
PYH2_k127_1508513_28 Hfq protein - - - 0.0000000000000000000000000007448 117.0
PYH2_k127_1508513_29 Tyrosine phosphatase family - - - 0.0000000000000000002131 95.0
PYH2_k127_1508513_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 563.0
PYH2_k127_1508513_30 - - - - 0.0000000000000006955 83.0
PYH2_k127_1508513_31 Domain of unknown function (DUF4412) - - - 0.0000000001736 72.0
PYH2_k127_1508513_32 Belongs to the UPF0312 family - - - 0.00000001086 64.0
PYH2_k127_1508513_33 Carboxypeptidase regulatory-like domain - - - 0.0001462 53.0
PYH2_k127_1508513_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 561.0
PYH2_k127_1508513_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 553.0
PYH2_k127_1508513_6 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 526.0
PYH2_k127_1508513_7 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 505.0
PYH2_k127_1508513_8 cystathionine gamma-synthase activity K01758,K01760,K01761 - 4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 489.0
PYH2_k127_1508513_9 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 470.0
PYH2_k127_1588595_0 Glycosyl transferase family 21 K11936 - - 0.0 1320.0
PYH2_k127_1588595_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 395.0
PYH2_k127_1588595_10 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000073 111.0
PYH2_k127_1588595_11 GtrA-like protein - - - 0.000000000000000000000001666 111.0
PYH2_k127_1588595_13 general secretion pathway protein K02246,K02456 - - 0.000233 51.0
PYH2_k127_1588595_2 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002607 237.0
PYH2_k127_1588595_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000005001 236.0
PYH2_k127_1588595_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000007289 215.0
PYH2_k127_1588595_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000004004 199.0
PYH2_k127_1588595_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000001037 187.0
PYH2_k127_1588595_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000003318 176.0
PYH2_k127_1588595_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000001629 188.0
PYH2_k127_1588595_9 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000004068 124.0
PYH2_k127_1629348_0 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 424.0
PYH2_k127_1629348_1 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 428.0
PYH2_k127_1629348_10 Beta-lactamase - - - 0.000007653 50.0
PYH2_k127_1629348_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 348.0
PYH2_k127_1629348_3 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 347.0
PYH2_k127_1629348_4 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 303.0
PYH2_k127_1629348_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000001796 199.0
PYH2_k127_1629348_6 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000001088 176.0
PYH2_k127_1629348_8 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000002831 83.0
PYH2_k127_1629348_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000002333 67.0
PYH2_k127_165293_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5.041e-301 947.0
PYH2_k127_165293_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 5.536e-197 622.0
PYH2_k127_165293_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 318.0
PYH2_k127_165293_11 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 313.0
PYH2_k127_165293_12 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000007424 234.0
PYH2_k127_165293_13 pfam ammecr1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000008741 214.0
PYH2_k127_165293_14 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000001442 171.0
PYH2_k127_165293_15 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000033 153.0
PYH2_k127_165293_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000005655 127.0
PYH2_k127_165293_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000000000000006991 119.0
PYH2_k127_165293_18 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.00000000000000000000000001023 123.0
PYH2_k127_165293_19 Lipopolysaccharide-assembly - - - 0.000000000000000000000001104 109.0
PYH2_k127_165293_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 567.0
PYH2_k127_165293_20 Domain of unknown function (DUF4081) K06976 - - 0.000000000000000000000002681 114.0
PYH2_k127_165293_21 domain, Protein - - - 0.0000000000000000000002033 100.0
PYH2_k127_165293_22 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000007364 80.0
PYH2_k127_165293_23 Chaperone protein DNAj - - - 0.00005057 53.0
PYH2_k127_165293_24 Domain of unknown function (DUF4926) - - - 0.00007616 55.0
PYH2_k127_165293_25 DnaJ molecular chaperone homology domain - - - 0.0003775 52.0
PYH2_k127_165293_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 572.0
PYH2_k127_165293_4 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 533.0
PYH2_k127_165293_5 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
PYH2_k127_165293_6 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 358.0
PYH2_k127_165293_7 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 355.0
PYH2_k127_165293_8 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 346.0
PYH2_k127_165293_9 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 338.0
PYH2_k127_1677736_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1081.0
PYH2_k127_1677736_1 4Fe-4S dicluster domain K00184 - - 7.444e-278 884.0
PYH2_k127_1677736_10 response regulator K07685 - - 0.00000000000000000000000000000000000000002009 161.0
PYH2_k127_1677736_11 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000002747 161.0
PYH2_k127_1677736_12 cytochrome c - - - 0.000000000000000000000000000000000000002489 153.0
PYH2_k127_1677736_13 Protein involved in hydrolase activity K06889 - - 0.00000000000000000000000000000000002937 148.0
PYH2_k127_1677736_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000004241 137.0
PYH2_k127_1677736_2 Polysulphide reductase, NrfD K00185 - - 5.154e-217 681.0
PYH2_k127_1677736_3 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 500.0
PYH2_k127_1677736_4 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 429.0
PYH2_k127_1677736_5 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 417.0
PYH2_k127_1677736_6 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 318.0
PYH2_k127_1677736_7 COGs COG1432 conserved - - - 0.000000000000000000000000000000000000000000000000000000000008062 213.0
PYH2_k127_1677736_8 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000116 188.0
PYH2_k127_1677736_9 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000002266 173.0
PYH2_k127_1677871_0 Dienelactone hydrolase family - - - 3.438e-247 779.0
PYH2_k127_1677871_1 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 485.0
PYH2_k127_1677871_2 SpoIID LytB domain protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 446.0
PYH2_k127_1677871_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 389.0
PYH2_k127_1677871_4 Domain of unknown function (DUF4922) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004452 247.0
PYH2_k127_1677871_5 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000005304 250.0
PYH2_k127_1677871_6 Ketosteroid isomerase-related protein - - - 0.000000000000000000000000000000000000000000000000002403 186.0
PYH2_k127_1677871_7 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000001905 145.0
PYH2_k127_1677871_8 Frataxin-like domain K06202 - - 0.0000000000000000002808 92.0
PYH2_k127_1677871_9 Protein of unknown function (DUF1460) - - - 0.00000000000000001784 91.0
PYH2_k127_1756416_0 Amidohydrolase family K01464 - 3.5.2.2 1.051e-207 654.0
PYH2_k127_1756416_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 584.0
PYH2_k127_1756416_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000005303 59.0
PYH2_k127_1756416_2 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 475.0
PYH2_k127_1756416_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 445.0
PYH2_k127_1756416_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 408.0
PYH2_k127_1756416_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008441 231.0
PYH2_k127_1756416_7 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000001226 174.0
PYH2_k127_1756416_8 - - - - 0.000000000000000000000000000000000000000001559 175.0
PYH2_k127_1756416_9 HEAT repeat - - - 0.00000000000001713 85.0
PYH2_k127_1763705_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1187.0
PYH2_k127_1763705_1 Malate synthase K01638 - 2.3.3.9 3.241e-262 814.0
PYH2_k127_1763705_10 - - - - 0.000000000000000000000000000000000001447 145.0
PYH2_k127_1763705_11 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000002355 137.0
PYH2_k127_1763705_12 von Willebrand factor, type A - - - 0.000000000000000000000000000000004805 142.0
PYH2_k127_1763705_14 radical SAM domain protein - - - 0.000000000000000001002 86.0
PYH2_k127_1763705_15 PFAM Forkhead-associated protein - - - 0.000000000000008026 84.0
PYH2_k127_1763705_16 TIGRFAM TonB family C-terminal domain K03832 - - 0.0000000000008847 78.0
PYH2_k127_1763705_17 PFAM SEC-C motif domain protein - - - 0.0000000005957 71.0
PYH2_k127_1763705_18 Tetratricopeptide repeat - - - 0.000008604 57.0
PYH2_k127_1763705_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 610.0
PYH2_k127_1763705_3 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 499.0
PYH2_k127_1763705_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 473.0
PYH2_k127_1763705_5 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 334.0
PYH2_k127_1763705_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 306.0
PYH2_k127_1763705_7 PQQ enzyme repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000009508 246.0
PYH2_k127_1763705_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000007161 172.0
PYH2_k127_1763705_9 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000004613 156.0
PYH2_k127_1795431_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1770.0
PYH2_k127_1795431_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1180.0
PYH2_k127_1795431_10 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 465.0
PYH2_k127_1795431_11 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 450.0
PYH2_k127_1795431_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 450.0
PYH2_k127_1795431_13 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 452.0
PYH2_k127_1795431_14 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 433.0
PYH2_k127_1795431_15 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 418.0
PYH2_k127_1795431_16 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 416.0
PYH2_k127_1795431_17 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 408.0
PYH2_k127_1795431_18 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 417.0
PYH2_k127_1795431_19 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 394.0
PYH2_k127_1795431_2 ThiC-associated domain K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.947e-310 961.0
PYH2_k127_1795431_20 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 387.0
PYH2_k127_1795431_21 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 400.0
PYH2_k127_1795431_22 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 335.0
PYH2_k127_1795431_23 cyclic nucleotide-binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 311.0
PYH2_k127_1795431_24 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 308.0
PYH2_k127_1795431_25 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 288.0
PYH2_k127_1795431_26 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002818 276.0
PYH2_k127_1795431_27 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006161 259.0
PYH2_k127_1795431_28 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 258.0
PYH2_k127_1795431_29 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005433 257.0
PYH2_k127_1795431_3 helicase superfamily c-terminal domain K03654 - 3.6.4.12 1.08e-243 771.0
PYH2_k127_1795431_30 Caulimovirus viroplasmin K06993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001432 253.0
PYH2_k127_1795431_31 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002646 235.0
PYH2_k127_1795431_32 Rossmann fold nucleotide-binding protein involved in DNA uptake - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 234.0
PYH2_k127_1795431_33 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
PYH2_k127_1795431_34 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000001854 210.0
PYH2_k127_1795431_35 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000002816 203.0
PYH2_k127_1795431_36 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000231 197.0
PYH2_k127_1795431_37 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000002081 203.0
PYH2_k127_1795431_39 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000009333 187.0
PYH2_k127_1795431_4 Carbon starvation protein K06200 - - 1.029e-217 693.0
PYH2_k127_1795431_40 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000000001288 181.0
PYH2_k127_1795431_41 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K05714 - 3.7.1.14 0.000000000000000000000000000000000000000000001035 179.0
PYH2_k127_1795431_42 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000002961 177.0
PYH2_k127_1795431_43 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000007174 158.0
PYH2_k127_1795431_44 - - - - 0.00000000000000000000000000000000000000004863 155.0
PYH2_k127_1795431_45 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000002415 163.0
PYH2_k127_1795431_46 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000006981 140.0
PYH2_k127_1795431_48 Ankyrin repeat K06867 - - 0.00000000000000000000000008029 121.0
PYH2_k127_1795431_49 ankyrin repeat K21440 - - 0.0000000000000003113 85.0
PYH2_k127_1795431_5 Peptidase S46 - - - 7.918e-213 684.0
PYH2_k127_1795431_50 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000009449 80.0
PYH2_k127_1795431_51 Domain of unknown function (DUF4149) - - - 0.00000000000001188 81.0
PYH2_k127_1795431_52 Dodecin K09165 - - 0.00000000000004881 75.0
PYH2_k127_1795431_53 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000009496 72.0
PYH2_k127_1795431_54 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000002775 81.0
PYH2_k127_1795431_55 DnaJ C terminal domain K09503 - - 0.000000000002626 75.0
PYH2_k127_1795431_56 Domain of unknown function (DU1801) - - - 0.000000000002701 67.0
PYH2_k127_1795431_57 - - - - 0.000000000007872 72.0
PYH2_k127_1795431_58 - - - - 0.0000002827 57.0
PYH2_k127_1795431_59 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634,K14166 - - 0.0000005286 60.0
PYH2_k127_1795431_6 Oxidoreductase domain protein - - - 8.99e-208 652.0
PYH2_k127_1795431_60 Protein of unknown function (DUF1697) - - - 0.000002652 56.0
PYH2_k127_1795431_61 Domain of unknown function (DU1801) - - - 0.000005238 51.0
PYH2_k127_1795431_62 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0009163 43.0
PYH2_k127_1795431_7 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 517.0
PYH2_k127_1795431_8 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 499.0
PYH2_k127_1795431_9 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 475.0
PYH2_k127_1795577_0 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 316.0
PYH2_k127_1795577_1 Domain of Unknown function (DUF542) K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000001618 243.0
PYH2_k127_1795577_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000005403 232.0
PYH2_k127_1795577_3 - - - - 0.00000000000000000000000000003707 123.0
PYH2_k127_1836382_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 526.0
PYH2_k127_1836382_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 482.0
PYH2_k127_1836382_10 cheY-homologous receiver domain - - - 0.00000000000008237 80.0
PYH2_k127_1836382_11 Protein of unknown function DUF58 - - - 0.000000002443 63.0
PYH2_k127_1836382_12 - - - - 0.0000001343 66.0
PYH2_k127_1836382_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 356.0
PYH2_k127_1836382_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 278.0
PYH2_k127_1836382_4 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000816 220.0
PYH2_k127_1836382_5 amine dehydrogenase activity - - - 0.000000000000000000000002627 108.0
PYH2_k127_1836382_6 Protein of unknown function (DUF1706) - - - 0.000000000000000000002885 100.0
PYH2_k127_1836382_8 DinB superfamily - - - 0.00000000000000001204 89.0
PYH2_k127_1836382_9 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000001702 92.0
PYH2_k127_1862571_0 SMART Elongator protein 3 MiaB NifB - - - 2.476e-234 737.0
PYH2_k127_1862571_1 radical SAM domain protein - - - 4.35e-229 720.0
PYH2_k127_1862571_10 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000002115 252.0
PYH2_k127_1862571_11 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000002163 247.0
PYH2_k127_1862571_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000003267 223.0
PYH2_k127_1862571_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003165 220.0
PYH2_k127_1862571_14 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000001157 211.0
PYH2_k127_1862571_15 PFAM peptidase K16922 - - 0.000000000000000000000000000000000000000000000000000004639 216.0
PYH2_k127_1862571_16 - - - - 0.00000000000000000000000000000000000000000000000000114 194.0
PYH2_k127_1862571_17 Protein kinase domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000005725 205.0
PYH2_k127_1862571_18 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000003576 186.0
PYH2_k127_1862571_19 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000003304 156.0
PYH2_k127_1862571_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 3.954e-194 617.0
PYH2_k127_1862571_20 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000006681 156.0
PYH2_k127_1862571_21 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000003265 142.0
PYH2_k127_1862571_22 Thioredoxin-like - - - 0.00000000000000000000003222 113.0
PYH2_k127_1862571_23 RNA recognition motif - - - 0.00000000000000000000003776 103.0
PYH2_k127_1862571_24 Pfam:N_methyl_2 - - - 0.0000000000000000000002593 102.0
PYH2_k127_1862571_25 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000003713 93.0
PYH2_k127_1862571_26 Pfam:N_methyl_2 - - - 0.00000000000000003174 87.0
PYH2_k127_1862571_27 Protein of unknown function (DUF3108) - - - 0.00000000000003633 84.0
PYH2_k127_1862571_28 PilZ domain - - - 0.0000006707 57.0
PYH2_k127_1862571_29 Sporulation related domain - - - 0.00001915 57.0
PYH2_k127_1862571_3 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 506.0
PYH2_k127_1862571_30 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0001355 51.0
PYH2_k127_1862571_4 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 496.0
PYH2_k127_1862571_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 413.0
PYH2_k127_1862571_6 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 385.0
PYH2_k127_1862571_7 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 318.0
PYH2_k127_1862571_8 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 317.0
PYH2_k127_1862571_9 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
PYH2_k127_1882776_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 601.0
PYH2_k127_1882776_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 576.0
PYH2_k127_1882776_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 506.0
PYH2_k127_1882776_3 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 417.0
PYH2_k127_1882776_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 336.0
PYH2_k127_1882776_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006824 275.0
PYH2_k127_1882776_6 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
PYH2_k127_1882776_7 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000016 147.0
PYH2_k127_1882776_8 serine-type peptidase activity - - - 0.000000000001094 68.0
PYH2_k127_1882776_9 Transposase - - - 0.000001907 53.0
PYH2_k127_1889508_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 8.592e-279 883.0
PYH2_k127_1889508_1 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 558.0
PYH2_k127_1889508_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 505.0
PYH2_k127_1889508_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004918 259.0
PYH2_k127_1889508_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000034 220.0
PYH2_k127_1889508_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000006093 206.0
PYH2_k127_1889508_6 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000001481 107.0
PYH2_k127_1960261_0 efflux transmembrane transporter activity - - - 2.905e-215 695.0
PYH2_k127_1960261_1 COG1228 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
PYH2_k127_1960261_2 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 313.0
PYH2_k127_1960261_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001059 246.0
PYH2_k127_1960261_4 PFAM SMP-30 Gluconolaconase - - - 0.0000003193 53.0
PYH2_k127_1976166_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0 1027.0
PYH2_k127_1976166_1 serine-type peptidase activity K01278 - 3.4.14.5 5.981e-319 990.0
PYH2_k127_1976166_10 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000009603 209.0
PYH2_k127_1976166_11 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000005247 208.0
PYH2_k127_1976166_12 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000003241 186.0
PYH2_k127_1976166_13 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000008628 184.0
PYH2_k127_1976166_14 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000001048 145.0
PYH2_k127_1976166_15 - - - - 0.00000000000000000000000000000000003353 139.0
PYH2_k127_1976166_17 PQQ enzyme repeat - - - 0.000000000000000000000000000005873 134.0
PYH2_k127_1976166_18 Protein of unknown function (DUF5131) - - - 0.00000000000000000000000000001001 121.0
PYH2_k127_1976166_19 Smr domain - - - 0.000000000000000000000000006782 114.0
PYH2_k127_1976166_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.17e-286 901.0
PYH2_k127_1976166_20 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000001205 117.0
PYH2_k127_1976166_22 conserved protein (COG2071) K09166 - - 0.000000000000000000007613 93.0
PYH2_k127_1976166_23 - - - - 0.00000000000000003459 85.0
PYH2_k127_1976166_24 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000003992 76.0
PYH2_k127_1976166_25 tail collar domain protein - - - 0.00000000007254 76.0
PYH2_k127_1976166_26 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.000001154 61.0
PYH2_k127_1976166_28 surface antigen - - - 0.00003255 57.0
PYH2_k127_1976166_29 Protein of unknown function (DUF1573) - - - 0.00005571 47.0
PYH2_k127_1976166_3 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 529.0
PYH2_k127_1976166_4 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 453.0
PYH2_k127_1976166_5 Pfam:Gp37_Gp68 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 397.0
PYH2_k127_1976166_6 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 379.0
PYH2_k127_1976166_7 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
PYH2_k127_1976166_8 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 334.0
PYH2_k127_1976166_9 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 297.0
PYH2_k127_2065245_0 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 377.0
PYH2_k127_2065245_1 Domain of unknown function (DUF4071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 377.0
PYH2_k127_2065245_10 Protein of unknown function (DUF5131) - - - 0.00006465 48.0
PYH2_k127_2065245_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 313.0
PYH2_k127_2065245_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000004058 263.0
PYH2_k127_2065245_4 PFAM WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000004201 202.0
PYH2_k127_2065245_5 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000662 143.0
PYH2_k127_2065245_6 Protein of unknown function (DUF4231) - - - 0.000000000000000000000000000000000006665 142.0
PYH2_k127_2065245_7 translation initiation factor activity - - - 0.000000000000000001956 87.0
PYH2_k127_2065245_8 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000003381 73.0
PYH2_k127_2065245_9 lysine biosynthesis protein LysW K05826 - - 0.0000000255 57.0
PYH2_k127_2092197_0 PQQ-like domain K00114 - 1.1.2.8 5.43e-243 760.0
PYH2_k127_2092197_1 oxidoreductase activity - - - 5.876e-194 631.0
PYH2_k127_2092197_10 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 375.0
PYH2_k127_2092197_11 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 358.0
PYH2_k127_2092197_12 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 353.0
PYH2_k127_2092197_13 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 351.0
PYH2_k127_2092197_14 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000007734 250.0
PYH2_k127_2092197_15 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000006693 237.0
PYH2_k127_2092197_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000002727 226.0
PYH2_k127_2092197_17 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000001666 218.0
PYH2_k127_2092197_18 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001106 201.0
PYH2_k127_2092197_19 Chitinase class I K03791 - - 0.0000000000000000000000000000000000000000000000000000001597 204.0
PYH2_k127_2092197_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 612.0
PYH2_k127_2092197_20 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000158 190.0
PYH2_k127_2092197_21 methyltransferase - - - 0.00000000000000000000000000000000000000000000001862 179.0
PYH2_k127_2092197_22 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000006573 183.0
PYH2_k127_2092197_23 Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate K00966,K16881 GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000001159 175.0
PYH2_k127_2092197_24 methyltransferase activity - - - 0.000000000000000000000000000000000000000004337 161.0
PYH2_k127_2092197_25 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000001541 156.0
PYH2_k127_2092197_26 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000002966 152.0
PYH2_k127_2092197_27 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000008605 147.0
PYH2_k127_2092197_28 - - - - 0.0000000000000000000000000000000000003976 154.0
PYH2_k127_2092197_29 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000001814 134.0
PYH2_k127_2092197_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 587.0
PYH2_k127_2092197_30 - - - - 0.000000000000000000000000001203 115.0
PYH2_k127_2092197_31 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000001342 116.0
PYH2_k127_2092197_32 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000002149 107.0
PYH2_k127_2092197_33 CYTH K05873 - 4.6.1.1 0.000000000000000000000004869 109.0
PYH2_k127_2092197_34 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.000000000000000000001319 98.0
PYH2_k127_2092197_35 - - - - 0.00000000000000004692 85.0
PYH2_k127_2092197_36 - - - - 0.0000000000000000847 84.0
PYH2_k127_2092197_39 Redoxin - - - 0.00000000000001293 77.0
PYH2_k127_2092197_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 496.0
PYH2_k127_2092197_40 Parallel beta-helix repeats - - - 0.000000003589 66.0
PYH2_k127_2092197_41 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.00000003048 61.0
PYH2_k127_2092197_42 23S rRNA-intervening sequence protein - - - 0.0000001465 53.0
PYH2_k127_2092197_43 Peroxiredoxin K03564 - 1.11.1.15 0.000000653 53.0
PYH2_k127_2092197_44 SMART serine threonine protein kinase - - - 0.0001483 48.0
PYH2_k127_2092197_45 PFAM glycosyl transferase family 9 - - - 0.0006682 51.0
PYH2_k127_2092197_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 477.0
PYH2_k127_2092197_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 485.0
PYH2_k127_2092197_7 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 466.0
PYH2_k127_2092197_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 413.0
PYH2_k127_2092197_9 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 391.0
PYH2_k127_2104655_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.857e-274 866.0
PYH2_k127_2104655_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.336e-218 684.0
PYH2_k127_2104655_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 530.0
PYH2_k127_2104655_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 441.0
PYH2_k127_2104655_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000002899 197.0
PYH2_k127_2104655_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.00006446 47.0
PYH2_k127_2120956_0 Tricorn protease homolog - - - 0.0 1459.0
PYH2_k127_2120956_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 585.0
PYH2_k127_2120956_10 amine dehydrogenase activity - - - 0.00000000000000000000006035 112.0
PYH2_k127_2120956_11 YCII-related domain - - - 0.000000000000000007377 93.0
PYH2_k127_2120956_12 amine dehydrogenase activity - - - 0.0000000000000003721 90.0
PYH2_k127_2120956_13 Protein conserved in bacteria - - - 0.00000000008636 72.0
PYH2_k127_2120956_14 Transcriptional regulator - - - 0.00000000881 60.0
PYH2_k127_2120956_15 cAMP biosynthetic process - - - 0.00003616 50.0
PYH2_k127_2120956_16 Belongs to the 5'-nucleotidase family K01081,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0002885 53.0
PYH2_k127_2120956_17 Required for the activity of the bacterial periplasmic transport system of putrescine - - - 0.0005638 48.0
PYH2_k127_2120956_2 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 537.0
PYH2_k127_2120956_4 Aldehyde dehydrogenase K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 437.0
PYH2_k127_2120956_5 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001175 247.0
PYH2_k127_2120956_6 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
PYH2_k127_2120956_7 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000003081 207.0
PYH2_k127_2120956_8 amine dehydrogenase activity - - - 0.000000000000000000000000003938 125.0
PYH2_k127_2120956_9 amine dehydrogenase activity - - - 0.0000000000000000000000004277 120.0
PYH2_k127_2187032_0 Cytochrome c - - - 0.0 1080.0
PYH2_k127_2187032_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 617.0
PYH2_k127_2187032_10 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000178 205.0
PYH2_k127_2187032_11 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000001203 183.0
PYH2_k127_2187032_12 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.000000000000000000000000000000000000000003016 164.0
PYH2_k127_2187032_13 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000000134 152.0
PYH2_k127_2187032_14 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000004034 112.0
PYH2_k127_2187032_15 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000000009819 116.0
PYH2_k127_2187032_17 cell redox homeostasis K03671 - - 0.00000000000000003544 83.0
PYH2_k127_2187032_2 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 556.0
PYH2_k127_2187032_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 454.0
PYH2_k127_2187032_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 453.0
PYH2_k127_2187032_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 297.0
PYH2_k127_2187032_6 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000002649 244.0
PYH2_k127_2187032_7 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003261 244.0
PYH2_k127_2187032_8 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000007079 239.0
PYH2_k127_2187032_9 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000000000000000000000008683 231.0
PYH2_k127_2195929_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 625.0
PYH2_k127_2195929_1 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 479.0
PYH2_k127_2195929_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 497.0
PYH2_k127_2195929_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 419.0
PYH2_k127_2195929_4 selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009144 254.0
PYH2_k127_2195929_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002128 181.0
PYH2_k127_2195929_6 antiporter activity - - - 0.0000000000000000000006487 97.0
PYH2_k127_2195929_7 Protein tyrosine kinase - - - 0.0000000000000004619 82.0
PYH2_k127_2240953_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.938e-295 917.0
PYH2_k127_2240953_1 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 578.0
PYH2_k127_2240953_10 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 265.0
PYH2_k127_2240953_11 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
PYH2_k127_2240953_12 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000003575 227.0
PYH2_k127_2240953_13 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
PYH2_k127_2240953_14 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000003288 227.0
PYH2_k127_2240953_15 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000132 189.0
PYH2_k127_2240953_16 Methenyl tetrahydrofolate cyclohydrolase - - - 0.000000000000000000000000000000000007848 145.0
PYH2_k127_2240953_17 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000002158 119.0
PYH2_k127_2240953_18 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000001818 103.0
PYH2_k127_2240953_19 ribonuclease BN K07058 - - 0.0000000000000000000003443 107.0
PYH2_k127_2240953_2 PFAM Peptidase M20 K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 576.0
PYH2_k127_2240953_20 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.0000002502 61.0
PYH2_k127_2240953_3 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 499.0
PYH2_k127_2240953_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 410.0
PYH2_k127_2240953_5 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 377.0
PYH2_k127_2240953_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 350.0
PYH2_k127_2240953_7 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 328.0
PYH2_k127_2240953_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 308.0
PYH2_k127_2240953_9 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 302.0
PYH2_k127_2264387_0 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 405.0
PYH2_k127_2264387_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 336.0
PYH2_k127_2266002_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 5.94e-257 824.0
PYH2_k127_2266002_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.302e-227 715.0
PYH2_k127_2266002_10 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 380.0
PYH2_k127_2266002_11 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 376.0
PYH2_k127_2266002_12 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 361.0
PYH2_k127_2266002_13 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 361.0
PYH2_k127_2266002_14 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 342.0
PYH2_k127_2266002_15 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 321.0
PYH2_k127_2266002_16 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 308.0
PYH2_k127_2266002_17 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 299.0
PYH2_k127_2266002_18 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 293.0
PYH2_k127_2266002_19 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000097 257.0
PYH2_k127_2266002_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 7.302e-194 616.0
PYH2_k127_2266002_20 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
PYH2_k127_2266002_21 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000004644 216.0
PYH2_k127_2266002_22 Protein of unknown function (DUF3179) - - - 0.000000000000000000000000000000000000000000000000001932 190.0
PYH2_k127_2266002_23 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.00000000000000000000000000000000000000000000002039 186.0
PYH2_k127_2266002_24 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000004026 183.0
PYH2_k127_2266002_25 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000002588 175.0
PYH2_k127_2266002_26 - - - - 0.00000000000000000000000000000000000000002247 153.0
PYH2_k127_2266002_27 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000001199 154.0
PYH2_k127_2266002_28 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000002549 147.0
PYH2_k127_2266002_29 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000002366 139.0
PYH2_k127_2266002_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 578.0
PYH2_k127_2266002_30 hydroperoxide reductase activity K01607 - 4.1.1.44 0.00000000000000000000000000000004313 126.0
PYH2_k127_2266002_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000002094 121.0
PYH2_k127_2266002_32 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000002997 105.0
PYH2_k127_2266002_33 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000002371 99.0
PYH2_k127_2266002_34 - - - - 0.000000000000000000004848 99.0
PYH2_k127_2266002_35 Caspase domain - - - 0.000000000000000000008083 108.0
PYH2_k127_2266002_36 Putative restriction endonuclease - - - 0.000000000000000000008899 95.0
PYH2_k127_2266002_37 VanZ like family - - - 0.000000000000000001347 91.0
PYH2_k127_2266002_38 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000002002 89.0
PYH2_k127_2266002_39 Transglycosylase associated protein - - - 0.0000000000000002669 82.0
PYH2_k127_2266002_4 SMART ATPase, AAA type, core K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 573.0
PYH2_k127_2266002_40 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000004919 76.0
PYH2_k127_2266002_41 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000002489 71.0
PYH2_k127_2266002_42 Transglutaminase-like superfamily - - - 0.00000000001179 71.0
PYH2_k127_2266002_43 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000001456 68.0
PYH2_k127_2266002_44 Protein of unknown function (DUF3179) - - - 0.0000000002273 69.0
PYH2_k127_2266002_45 cAMP biosynthetic process - - - 0.0000000007791 61.0
PYH2_k127_2266002_46 Protein of unknown function (DUF2889) - - - 0.000003319 56.0
PYH2_k127_2266002_47 Redoxin - - - 0.000003938 55.0
PYH2_k127_2266002_48 ATP synthesis coupled proton transport K02109 - - 0.0001304 51.0
PYH2_k127_2266002_49 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0006581 50.0
PYH2_k127_2266002_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 522.0
PYH2_k127_2266002_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 472.0
PYH2_k127_2266002_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 437.0
PYH2_k127_2266002_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 414.0
PYH2_k127_2266002_9 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 418.0
PYH2_k127_2295604_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1106.0
PYH2_k127_2295604_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1068.0
PYH2_k127_2295604_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 316.0
PYH2_k127_2295604_11 transcriptional regulator K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 308.0
PYH2_k127_2295604_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 313.0
PYH2_k127_2295604_13 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 295.0
PYH2_k127_2295604_14 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000009766 237.0
PYH2_k127_2295604_15 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000004256 239.0
PYH2_k127_2295604_16 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000034 229.0
PYH2_k127_2295604_17 - - - - 0.000000000000000000000000000000000000000000000000000000000001195 227.0
PYH2_k127_2295604_18 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000008289 207.0
PYH2_k127_2295604_19 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000001418 186.0
PYH2_k127_2295604_2 ASPIC and UnbV - - - 1.043e-202 647.0
PYH2_k127_2295604_20 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000002191 186.0
PYH2_k127_2295604_21 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000006098 171.0
PYH2_k127_2295604_22 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000009843 154.0
PYH2_k127_2295604_23 Na -dependent transporter K03453 - - 0.000000000000000000000000000008719 127.0
PYH2_k127_2295604_24 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000003844 105.0
PYH2_k127_2295604_25 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.0000000000000005197 82.0
PYH2_k127_2295604_26 MacB-like periplasmic core domain - - - 0.00000000000001198 82.0
PYH2_k127_2295604_28 Hep Hag repeat protein - - - 0.000007081 59.0
PYH2_k127_2295604_3 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 542.0
PYH2_k127_2295604_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 476.0
PYH2_k127_2295604_5 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 446.0
PYH2_k127_2295604_6 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 418.0
PYH2_k127_2295604_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 376.0
PYH2_k127_2295604_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 360.0
PYH2_k127_2295604_9 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 329.0
PYH2_k127_2316177_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.551e-305 952.0
PYH2_k127_2316177_1 MacB-like periplasmic core domain - - - 1.279e-252 803.0
PYH2_k127_2316177_10 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 286.0
PYH2_k127_2316177_11 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 289.0
PYH2_k127_2316177_12 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 290.0
PYH2_k127_2316177_13 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 280.0
PYH2_k127_2316177_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
PYH2_k127_2316177_15 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001633 272.0
PYH2_k127_2316177_16 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000001347 262.0
PYH2_k127_2316177_17 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000004458 244.0
PYH2_k127_2316177_18 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000004079 235.0
PYH2_k127_2316177_19 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000008274 210.0
PYH2_k127_2316177_2 glucan 1,4-alpha-glucosidase activity - - - 4.233e-246 779.0
PYH2_k127_2316177_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000004137 200.0
PYH2_k127_2316177_21 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000001888 187.0
PYH2_k127_2316177_22 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000006989 188.0
PYH2_k127_2316177_23 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000000000002913 184.0
PYH2_k127_2316177_24 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000005413 179.0
PYH2_k127_2316177_25 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000002862 152.0
PYH2_k127_2316177_26 PFAM microcompartments protein K04027 - - 0.00000000000000000000000000000000001952 139.0
PYH2_k127_2316177_27 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000001949 134.0
PYH2_k127_2316177_28 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000000000000000007642 124.0
PYH2_k127_2316177_29 chlorophyll binding - - - 0.0000000000000000000000009253 113.0
PYH2_k127_2316177_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 592.0
PYH2_k127_2316177_30 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000002253 100.0
PYH2_k127_2316177_31 Chorismate mutase type II K03856,K04092,K04093,K04516,K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000007847 97.0
PYH2_k127_2316177_32 Alpha/beta hydrolase family - - - 0.00000000000000000001328 102.0
PYH2_k127_2316177_33 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000002161 98.0
PYH2_k127_2316177_34 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000005181 88.0
PYH2_k127_2316177_35 - - - - 0.0000000000000001163 84.0
PYH2_k127_2316177_36 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000186 93.0
PYH2_k127_2316177_38 Helix-turn-helix domain - - - 0.00000000000001325 85.0
PYH2_k127_2316177_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 571.0
PYH2_k127_2316177_40 cAMP biosynthetic process K03641 - - 0.000000005514 59.0
PYH2_k127_2316177_41 CHRD domain - - - 0.00000002888 65.0
PYH2_k127_2316177_42 Putative restriction endonuclease - - - 0.0000001021 57.0
PYH2_k127_2316177_43 hydrolase activity, acting on ester bonds - - - 0.000002578 49.0
PYH2_k127_2316177_44 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00006632 53.0
PYH2_k127_2316177_45 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0007487 45.0
PYH2_k127_2316177_5 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 572.0
PYH2_k127_2316177_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 512.0
PYH2_k127_2316177_7 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 492.0
PYH2_k127_2316177_8 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 471.0
PYH2_k127_2316177_9 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 466.0
PYH2_k127_2348633_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 1.051e-218 688.0
PYH2_k127_2348633_1 Glucuronate isomerase K01812 - 5.3.1.12 2.022e-210 662.0
PYH2_k127_2348633_10 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 400.0
PYH2_k127_2348633_11 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 391.0
PYH2_k127_2348633_12 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 384.0
PYH2_k127_2348633_13 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
PYH2_k127_2348633_14 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007748 281.0
PYH2_k127_2348633_15 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.00000000000000000000000000000000003513 138.0
PYH2_k127_2348633_16 - - - - 0.00000000000000000000000000000003086 137.0
PYH2_k127_2348633_17 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000001568 109.0
PYH2_k127_2348633_18 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.00000000000000006598 96.0
PYH2_k127_2348633_19 Acyl-CoA synthetase - - - 0.0000000000002151 71.0
PYH2_k127_2348633_2 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 2.375e-210 660.0
PYH2_k127_2348633_3 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 3.855e-194 611.0
PYH2_k127_2348633_4 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 480.0
PYH2_k127_2348633_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 475.0
PYH2_k127_2348633_6 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 462.0
PYH2_k127_2348633_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 432.0
PYH2_k127_2348633_8 inositol monophosphate 1-phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 418.0
PYH2_k127_2348633_9 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 404.0
PYH2_k127_2426334_0 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 414.0
PYH2_k127_2426334_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 343.0
PYH2_k127_2426334_2 HemY domain protein - - - 0.000000000000000000000000000000000000000000000008605 199.0
PYH2_k127_2426334_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000003035 163.0
PYH2_k127_2426334_4 YhhN family - - - 0.000000000000000000000000000000000001444 147.0
PYH2_k127_2426334_5 metallopeptidase activity K08738,K20276 - - 0.000000000000000000000001447 122.0
PYH2_k127_2426334_6 - - - - 0.00000003296 64.0
PYH2_k127_2481_0 Cytochrome c - - - 6.358e-204 662.0
PYH2_k127_2481_1 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 300.0
PYH2_k127_2481_2 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000002236 231.0
PYH2_k127_2481_3 - - - - 0.0000000000000000000000000000000000000000000000000003474 190.0
PYH2_k127_2481_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000000000000000000000000000000000063 185.0
PYH2_k127_2481_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000000000000000000000002697 169.0
PYH2_k127_2481_6 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.000000000000000000000000000000000000003035 148.0
PYH2_k127_2481_7 - - - - 0.0000000000000000000000000000004392 132.0
PYH2_k127_2481_8 Belongs to the 'phage' integrase family K04763 - - 0.0000007615 54.0
PYH2_k127_2514625_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1507.0
PYH2_k127_2514625_1 PFAM Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1502.0
PYH2_k127_2514625_10 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 1.065e-228 726.0
PYH2_k127_2514625_11 PFAM peptidase M1, membrane alanine aminopeptidase - - - 1.841e-226 713.0
PYH2_k127_2514625_12 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 9.449e-214 675.0
PYH2_k127_2514625_13 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 615.0
PYH2_k127_2514625_14 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 574.0
PYH2_k127_2514625_15 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 564.0
PYH2_k127_2514625_16 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 486.0
PYH2_k127_2514625_17 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 473.0
PYH2_k127_2514625_18 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 466.0
PYH2_k127_2514625_19 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 465.0
PYH2_k127_2514625_2 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1402.0
PYH2_k127_2514625_20 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 452.0
PYH2_k127_2514625_21 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 377.0
PYH2_k127_2514625_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 376.0
PYH2_k127_2514625_23 regulation of single-species biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 362.0
PYH2_k127_2514625_24 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 362.0
PYH2_k127_2514625_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 325.0
PYH2_k127_2514625_26 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 313.0
PYH2_k127_2514625_27 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 299.0
PYH2_k127_2514625_28 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 283.0
PYH2_k127_2514625_29 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
PYH2_k127_2514625_3 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.776e-292 913.0
PYH2_k127_2514625_30 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH2_k127_2514625_31 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001062 278.0
PYH2_k127_2514625_32 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004316 252.0
PYH2_k127_2514625_33 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000001497 247.0
PYH2_k127_2514625_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008383 251.0
PYH2_k127_2514625_35 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000004202 204.0
PYH2_k127_2514625_36 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000001743 205.0
PYH2_k127_2514625_37 DinB family - - - 0.0000000000000000000000000000000000000000000000000000002239 198.0
PYH2_k127_2514625_38 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000001451 200.0
PYH2_k127_2514625_39 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000005656 173.0
PYH2_k127_2514625_4 Phosphate acyltransferases K01897 - 6.2.1.3 1.617e-264 842.0
PYH2_k127_2514625_40 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000006687 179.0
PYH2_k127_2514625_41 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000006187 166.0
PYH2_k127_2514625_42 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000005917 177.0
PYH2_k127_2514625_43 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000005267 161.0
PYH2_k127_2514625_44 Thioredoxin - - - 0.00000000000000000000000000000000000000009791 161.0
PYH2_k127_2514625_45 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000003242 149.0
PYH2_k127_2514625_46 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000002429 136.0
PYH2_k127_2514625_47 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.000000000000000000000000000000004021 140.0
PYH2_k127_2514625_48 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000001069 134.0
PYH2_k127_2514625_49 - - - - 0.00000000000000000000000000000001391 131.0
PYH2_k127_2514625_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.838e-262 822.0
PYH2_k127_2514625_50 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000001325 112.0
PYH2_k127_2514625_51 - - - - 0.0000000000000000000001346 105.0
PYH2_k127_2514625_52 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.000000000000000000006285 93.0
PYH2_k127_2514625_53 lysyltransferase activity K07027 - - 0.000000000000000000006757 105.0
PYH2_k127_2514625_54 CarD-like/TRCF domain K07736 - - 0.0000000000000000001564 95.0
PYH2_k127_2514625_55 SMART RNP-1 like RNA-binding protein - - - 0.0000000000000000001694 90.0
PYH2_k127_2514625_56 glutamine amidotransferase K01951 - 6.3.5.2 0.00000000000000006683 83.0
PYH2_k127_2514625_57 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000461 84.0
PYH2_k127_2514625_58 - - - - 0.000000000000001594 86.0
PYH2_k127_2514625_59 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.000000000007042 70.0
PYH2_k127_2514625_6 Belongs to the amidase family K01426 - 3.5.1.4 8.393e-259 806.0
PYH2_k127_2514625_60 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000002147 66.0
PYH2_k127_2514625_62 - - - - 0.000000001683 65.0
PYH2_k127_2514625_63 Family of unknown function (DUF5335) - - - 0.00000001143 61.0
PYH2_k127_2514625_64 Multicopper oxidase K04753 - - 0.00000001983 68.0
PYH2_k127_2514625_65 zinc ion binding K06204 - - 0.00000002126 63.0
PYH2_k127_2514625_66 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000002276 65.0
PYH2_k127_2514625_68 deoxyhypusine monooxygenase activity - - - 0.0000003013 60.0
PYH2_k127_2514625_69 Belongs to the iron ascorbate-dependent oxidoreductase family - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.000001301 51.0
PYH2_k127_2514625_7 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 6.206e-240 756.0
PYH2_k127_2514625_70 - - - - 0.000002188 57.0
PYH2_k127_2514625_71 - - - - 0.00001778 53.0
PYH2_k127_2514625_72 ECF sigma factor - - - 0.0001527 46.0
PYH2_k127_2514625_73 lysozyme activity - - - 0.0001684 50.0
PYH2_k127_2514625_74 PFAM PEGA domain - - - 0.000718 48.0
PYH2_k127_2514625_8 peptidase - - - 1.662e-231 736.0
PYH2_k127_2514625_9 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 2.559e-231 725.0
PYH2_k127_2520513_0 Amino acid permease - - - 9.256e-248 786.0
PYH2_k127_2520513_1 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 4.35e-227 710.0
PYH2_k127_2520513_10 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 399.0
PYH2_k127_2520513_11 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 384.0
PYH2_k127_2520513_12 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 393.0
PYH2_k127_2520513_13 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 344.0
PYH2_k127_2520513_14 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
PYH2_k127_2520513_15 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 304.0
PYH2_k127_2520513_16 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007385 288.0
PYH2_k127_2520513_17 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001919 236.0
PYH2_k127_2520513_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000005386 239.0
PYH2_k127_2520513_19 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000000000000000000000000000000005491 258.0
PYH2_k127_2520513_2 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 2.535e-200 636.0
PYH2_k127_2520513_20 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000005493 239.0
PYH2_k127_2520513_21 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000004654 229.0
PYH2_k127_2520513_22 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000001705 233.0
PYH2_k127_2520513_23 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000001861 224.0
PYH2_k127_2520513_24 - - - - 0.00000000000000000000000000000000000000000000000000009958 202.0
PYH2_k127_2520513_25 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000004222 207.0
PYH2_k127_2520513_26 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000002173 184.0
PYH2_k127_2520513_27 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000000000000009458 171.0
PYH2_k127_2520513_28 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000005799 153.0
PYH2_k127_2520513_29 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000007748 159.0
PYH2_k127_2520513_3 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 595.0
PYH2_k127_2520513_30 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000007123 108.0
PYH2_k127_2520513_31 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000002716 100.0
PYH2_k127_2520513_32 alpha beta - - - 0.00000000000000000001988 109.0
PYH2_k127_2520513_33 Protein of unknown function (DUF1573) - - - 0.000000000000001116 87.0
PYH2_k127_2520513_35 Tfp pilus assembly protein FimV - - - 0.00000000000001489 82.0
PYH2_k127_2520513_36 zinc-ribbon domain - - - 0.0000000000002207 79.0
PYH2_k127_2520513_38 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000007664 77.0
PYH2_k127_2520513_39 cellulase activity - - - 0.000000001452 73.0
PYH2_k127_2520513_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 544.0
PYH2_k127_2520513_41 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000009868 53.0
PYH2_k127_2520513_42 Endonuclease Exonuclease Phosphatase K07004 - - 0.00004148 58.0
PYH2_k127_2520513_43 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0002861 52.0
PYH2_k127_2520513_44 Type IV Pilus-assembly protein W K02672 - - 0.0003011 52.0
PYH2_k127_2520513_45 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0004594 51.0
PYH2_k127_2520513_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 493.0
PYH2_k127_2520513_6 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 452.0
PYH2_k127_2520513_7 N-4 methylation of cytosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 456.0
PYH2_k127_2520513_8 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 451.0
PYH2_k127_2520513_9 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 443.0
PYH2_k127_2527647_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1300.0
PYH2_k127_2527647_1 Peptidase M16 - - - 0.0 1165.0
PYH2_k127_2527647_10 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 329.0
PYH2_k127_2527647_11 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008684 284.0
PYH2_k127_2527647_12 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002503 252.0
PYH2_k127_2527647_13 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000006438 235.0
PYH2_k127_2527647_14 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000009852 229.0
PYH2_k127_2527647_15 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000006558 217.0
PYH2_k127_2527647_16 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000002683 193.0
PYH2_k127_2527647_17 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000000000000000000000000000000000004688 187.0
PYH2_k127_2527647_18 Ankyrin repeat - - - 0.00000000000000000000000000000005685 135.0
PYH2_k127_2527647_2 PFAM blue (type 1) copper domain protein - - - 5.135e-280 873.0
PYH2_k127_2527647_20 Protein of unknown function (DUF1059) - - - 0.00000000000000001493 84.0
PYH2_k127_2527647_21 Forkhead associated domain - - - 0.00000000000000026 91.0
PYH2_k127_2527647_22 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000005062 66.0
PYH2_k127_2527647_24 Zinc finger domain K04043 - - 0.0000568 55.0
PYH2_k127_2527647_3 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 565.0
PYH2_k127_2527647_4 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 520.0
PYH2_k127_2527647_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 509.0
PYH2_k127_2527647_6 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 439.0
PYH2_k127_2527647_7 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 432.0
PYH2_k127_2527647_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 381.0
PYH2_k127_2527647_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 334.0
PYH2_k127_2533729_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 5.817e-290 898.0
PYH2_k127_2533729_1 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006067 286.0
PYH2_k127_2533729_2 PAS fold - - - 0.0000000000000000000000000000000000000004399 151.0
PYH2_k127_2534770_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 8.642e-292 915.0
PYH2_k127_2534770_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 443.0
PYH2_k127_2534770_10 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000001431 219.0
PYH2_k127_2534770_11 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000000002143 153.0
PYH2_k127_2534770_12 LysM domain K08307,K12204 - - 0.000000000000000000000000000000000000007613 160.0
PYH2_k127_2534770_13 Domain of unknown function (DUF1844) - - - 0.000000000000003843 83.0
PYH2_k127_2534770_14 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000204 76.0
PYH2_k127_2534770_2 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 362.0
PYH2_k127_2534770_3 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 333.0
PYH2_k127_2534770_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 292.0
PYH2_k127_2534770_5 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000002801 270.0
PYH2_k127_2534770_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002995 268.0
PYH2_k127_2534770_7 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000003953 266.0
PYH2_k127_2534770_8 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002852 260.0
PYH2_k127_2534770_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
PYH2_k127_2540564_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 451.0
PYH2_k127_2540564_1 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 395.0
PYH2_k127_2540564_2 NADPH-dependent f420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000002552 138.0
PYH2_k127_2542367_0 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 5.219e-215 686.0
PYH2_k127_2542367_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 420.0
PYH2_k127_2542367_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000001304 250.0
PYH2_k127_2542367_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001761 253.0
PYH2_k127_2542367_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000002169 228.0
PYH2_k127_2542367_13 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000003884 213.0
PYH2_k127_2542367_14 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000009644 211.0
PYH2_k127_2542367_15 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000008581 178.0
PYH2_k127_2542367_16 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000000476 149.0
PYH2_k127_2542367_17 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000429 144.0
PYH2_k127_2542367_18 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000002524 153.0
PYH2_k127_2542367_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000009179 118.0
PYH2_k127_2542367_2 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 440.0
PYH2_k127_2542367_20 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000005675 105.0
PYH2_k127_2542367_21 - - - - 0.0000000000000000001037 104.0
PYH2_k127_2542367_22 NosL - - - 0.0000000000000002916 85.0
PYH2_k127_2542367_23 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000009415 85.0
PYH2_k127_2542367_24 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000007233 72.0
PYH2_k127_2542367_25 Prokaryotic N-terminal methylation motif - - - 0.000000005184 63.0
PYH2_k127_2542367_26 - - - - 0.00000002429 57.0
PYH2_k127_2542367_27 PFAM glycosyl transferase family 39 - - - 0.0000003644 63.0
PYH2_k127_2542367_3 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 389.0
PYH2_k127_2542367_4 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 404.0
PYH2_k127_2542367_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 387.0
PYH2_k127_2542367_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 306.0
PYH2_k127_2542367_7 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002107 287.0
PYH2_k127_2542367_8 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003237 271.0
PYH2_k127_2542367_9 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000005989 248.0
PYH2_k127_2588478_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1108.0
PYH2_k127_2588478_1 Belongs to the IlvD Edd family K01690 - 4.2.1.12 3.435e-285 886.0
PYH2_k127_2588478_2 gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 487.0
PYH2_k127_2588478_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 430.0
PYH2_k127_2588478_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 396.0
PYH2_k127_2588478_5 MscS Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 385.0
PYH2_k127_2588478_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004777 276.0
PYH2_k127_2588478_7 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 256.0
PYH2_k127_2588478_9 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000003524 142.0
PYH2_k127_2604637_0 Protein tyrosine kinase - - - 2.363e-210 683.0
PYH2_k127_2604637_1 Protein tyrosine kinase - - - 2.461e-194 636.0
PYH2_k127_2604637_10 hmm pf00665 - - - 0.000002599 50.0
PYH2_k127_2604637_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002616 259.0
PYH2_k127_2604637_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000003116 206.0
PYH2_k127_2604637_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001746 206.0
PYH2_k127_2604637_5 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000009065 181.0
PYH2_k127_2604637_6 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000002138 168.0
PYH2_k127_2604637_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000005951 156.0
PYH2_k127_2604637_8 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000006927 93.0
PYH2_k127_2604637_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000004481 75.0
PYH2_k127_2608558_0 Tricorn protease C1 domain K08676 - - 0.0 1047.0
PYH2_k127_2608558_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 622.0
PYH2_k127_2608558_10 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 336.0
PYH2_k127_2608558_11 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 318.0
PYH2_k127_2608558_12 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001623 286.0
PYH2_k127_2608558_13 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000001035 256.0
PYH2_k127_2608558_14 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004009 235.0
PYH2_k127_2608558_15 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
PYH2_k127_2608558_16 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000008784 226.0
PYH2_k127_2608558_17 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000002315 232.0
PYH2_k127_2608558_18 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000002344 188.0
PYH2_k127_2608558_19 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000626 194.0
PYH2_k127_2608558_2 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 611.0
PYH2_k127_2608558_20 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000002566 181.0
PYH2_k127_2608558_21 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000767 149.0
PYH2_k127_2608558_22 Domain of unknown function (DUF4350) - - - 0.000000000000000000000000000000003481 143.0
PYH2_k127_2608558_23 Thioesterase-like superfamily - - - 0.0000000000000000000000000000002028 132.0
PYH2_k127_2608558_24 Phosphoglycerate mutase family - - - 0.00000000000000000000001218 109.0
PYH2_k127_2608558_25 PIN domain - - - 0.000000000000003123 76.0
PYH2_k127_2608558_26 SPTR PilT protein domain protein - - - 0.000000001752 59.0
PYH2_k127_2608558_27 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000006074 63.0
PYH2_k127_2608558_28 - - - - 0.00004439 54.0
PYH2_k127_2608558_29 PFAM Sporulation domain protein - - - 0.0006794 49.0
PYH2_k127_2608558_3 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 544.0
PYH2_k127_2608558_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 441.0
PYH2_k127_2608558_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 405.0
PYH2_k127_2608558_6 PCRF K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 390.0
PYH2_k127_2608558_7 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 384.0
PYH2_k127_2608558_8 Belongs to the Pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 362.0
PYH2_k127_2608558_9 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 347.0
PYH2_k127_2660708_0 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 601.0
PYH2_k127_2660708_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 471.0
PYH2_k127_2660708_10 Nucleotidyltransferase domain - - - 0.0000005607 57.0
PYH2_k127_2660708_2 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 347.0
PYH2_k127_2660708_3 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 294.0
PYH2_k127_2660708_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000002303 183.0
PYH2_k127_2660708_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000002153 186.0
PYH2_k127_2660708_6 - - - - 0.00000000000000000000000000000000000000000000005131 176.0
PYH2_k127_2660708_7 Yqey-like protein K09117 - - 0.000000000000000000000000000000000003255 142.0
PYH2_k127_2660708_8 HEPN domain - - - 0.0000000000000000000000000000000007284 134.0
PYH2_k127_2660708_9 Tyrosine phosphatase family - - - 0.00000000000000000000195 102.0
PYH2_k127_270118_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 595.0
PYH2_k127_270118_1 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 569.0
PYH2_k127_270118_10 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 252.0
PYH2_k127_270118_11 - - - - 0.00000000000000000000000000000000000003685 164.0
PYH2_k127_270118_12 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.0000000000000000000000000000000007461 151.0
PYH2_k127_270118_13 glycosyl transferase family 2 - - - 0.000000000000000000000000000008597 132.0
PYH2_k127_270118_14 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000001761 116.0
PYH2_k127_270118_15 - - - - 0.0000000000000000000001897 97.0
PYH2_k127_270118_16 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000547 81.0
PYH2_k127_270118_17 Protein of unknown function (DUF433) - - - 0.000000000000867 70.0
PYH2_k127_270118_18 HEPN domain - - - 0.00000001899 57.0
PYH2_k127_270118_19 - - - - 0.00000002157 56.0
PYH2_k127_270118_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 591.0
PYH2_k127_270118_20 heat shock protein binding - - - 0.000007631 57.0
PYH2_k127_270118_21 Peptidase M16 inactive domain K07263 - - 0.00002284 55.0
PYH2_k127_270118_22 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000065 56.0
PYH2_k127_270118_3 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 489.0
PYH2_k127_270118_4 RQC K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 482.0
PYH2_k127_270118_5 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 472.0
PYH2_k127_270118_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 410.0
PYH2_k127_270118_7 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 344.0
PYH2_k127_270118_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 329.0
PYH2_k127_270118_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 296.0
PYH2_k127_2704958_0 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 548.0
PYH2_k127_2704958_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 510.0
PYH2_k127_2704958_10 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000001737 261.0
PYH2_k127_2704958_11 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002194 255.0
PYH2_k127_2704958_12 - - - - 0.00000000000000000000000000000000000000000000005639 180.0
PYH2_k127_2704958_13 - - - - 0.00000000000000000000000000000000000000005082 155.0
PYH2_k127_2704958_14 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000001581 153.0
PYH2_k127_2704958_15 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000007902 148.0
PYH2_k127_2704958_16 FR47-like protein - - - 0.000000000000000000000000000000000007546 141.0
PYH2_k127_2704958_17 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000001074 148.0
PYH2_k127_2704958_18 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000009984 123.0
PYH2_k127_2704958_19 Tyrosine phosphatase family - - - 0.0000000000000000000000003869 112.0
PYH2_k127_2704958_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 516.0
PYH2_k127_2704958_20 Bacterial PH domain - - - 0.000000001789 66.0
PYH2_k127_2704958_21 RNA binding - - - 0.000213 46.0
PYH2_k127_2704958_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 484.0
PYH2_k127_2704958_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 469.0
PYH2_k127_2704958_5 Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 399.0
PYH2_k127_2704958_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 381.0
PYH2_k127_2704958_7 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 325.0
PYH2_k127_2704958_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 295.0
PYH2_k127_2704958_9 Lycopene cyclase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009501 271.0
PYH2_k127_2713563_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1023.0
PYH2_k127_2713563_1 Dienelactone hydrolase family - - - 5.034e-275 869.0
PYH2_k127_2713563_10 SnoaL-like domain - - - 0.000000001185 64.0
PYH2_k127_2713563_11 homolog subfamily B member K09518 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006457,GO:0006458,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0019538,GO:0022607,GO:0030163,GO:0030176,GO:0030544,GO:0031072,GO:0031224,GO:0031227,GO:0031984,GO:0033554,GO:0034622,GO:0034976,GO:0035966,GO:0035967,GO:0036503,GO:0042175,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051084,GO:0051085,GO:0051603,GO:0051716,GO:0051788,GO:0061077,GO:0065003,GO:0070887,GO:0071218,GO:0071310,GO:0071704,GO:0071840,GO:0098827,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - 0.00000004356 65.0
PYH2_k127_2713563_2 AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 556.0
PYH2_k127_2713563_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 491.0
PYH2_k127_2713563_4 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 372.0
PYH2_k127_2713563_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 386.0
PYH2_k127_2713563_6 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 372.0
PYH2_k127_2713563_7 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 283.0
PYH2_k127_2713563_8 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000006788 89.0
PYH2_k127_2713563_9 - - - - 0.000000000001713 70.0
PYH2_k127_2743147_0 PFAM helicase domain protein - - - 0.0 1872.0
PYH2_k127_2743147_1 Protein of unknown function (DUF1156) K07445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 532.0
PYH2_k127_2743147_10 B-1 B cell differentiation - - - 0.00000001525 68.0
PYH2_k127_2743147_2 - K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 524.0
PYH2_k127_2743147_3 plasmid maintenance K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 460.0
PYH2_k127_2743147_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 387.0
PYH2_k127_2743147_5 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000001235 193.0
PYH2_k127_2743147_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000001042 153.0
PYH2_k127_2743147_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000001227 130.0
PYH2_k127_2743147_8 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000001595 112.0
PYH2_k127_2743147_9 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000001533 85.0
PYH2_k127_275667_0 GMC oxidoreductase - - - 1.054e-234 741.0
PYH2_k127_275667_1 efflux transmembrane transporter activity K02004 - - 4.509e-221 713.0
PYH2_k127_275667_10 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000839 189.0
PYH2_k127_275667_11 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000001618 185.0
PYH2_k127_275667_12 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000001065 184.0
PYH2_k127_275667_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000009854 167.0
PYH2_k127_275667_14 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002579 166.0
PYH2_k127_275667_15 BMC K04025 - - 0.000000000000000000000000000000000000004002 152.0
PYH2_k127_275667_16 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000000000000006948 150.0
PYH2_k127_275667_17 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000004808 132.0
PYH2_k127_275667_18 - - - - 0.000000000000000000000000002977 112.0
PYH2_k127_275667_19 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000002541 97.0
PYH2_k127_275667_2 efflux transmembrane transporter activity - - - 4.206e-201 653.0
PYH2_k127_275667_20 - - - - 0.0000000000000002443 83.0
PYH2_k127_275667_21 ribonuclease activity - - - 0.0000000000000005129 80.0
PYH2_k127_275667_22 Pfam Sulfatase - - - 0.000000000000614 72.0
PYH2_k127_275667_24 23S rRNA-intervening sequence protein - - - 0.00001434 48.0
PYH2_k127_275667_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 600.0
PYH2_k127_275667_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 444.0
PYH2_k127_275667_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 338.0
PYH2_k127_275667_6 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 333.0
PYH2_k127_275667_7 cobalamin binding K01647,K18997,K22491 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000005083 253.0
PYH2_k127_275667_8 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000117 217.0
PYH2_k127_275667_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000004373 190.0
PYH2_k127_2807670_0 cytochrome C - - - 0.0 1158.0
PYH2_k127_2807670_1 Protein of unknown function (DUF1501) - - - 1.876e-222 702.0
PYH2_k127_2807670_10 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000001685 189.0
PYH2_k127_2807670_11 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000001078 181.0
PYH2_k127_2807670_12 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000001527 160.0
PYH2_k127_2807670_13 Domain of unknown function (DUF4287) - - - 0.0000000000000000000000000000000000002151 143.0
PYH2_k127_2807670_14 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000001057 145.0
PYH2_k127_2807670_15 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000445 145.0
PYH2_k127_2807670_16 Belongs to the ompA family K03286 - - 0.00000000000000009633 89.0
PYH2_k127_2807670_17 Periplasmic or secreted lipoprotein - - - 0.00000000000005526 81.0
PYH2_k127_2807670_19 Matrixin - - - 0.0000000001005 75.0
PYH2_k127_2807670_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 612.0
PYH2_k127_2807670_20 Protein of unknown function (DUF1214) - - - 0.0000000789 55.0
PYH2_k127_2807670_3 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 408.0
PYH2_k127_2807670_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 378.0
PYH2_k127_2807670_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
PYH2_k127_2807670_6 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004425 287.0
PYH2_k127_2807670_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001039 256.0
PYH2_k127_2807670_8 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000006077 248.0
PYH2_k127_2807670_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000002135 214.0
PYH2_k127_2893783_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001205 190.0
PYH2_k127_2893783_1 - - - - 0.0000000000000000000000000000000000000000000001048 179.0
PYH2_k127_2893783_4 SPFH domain-Band 7 family - - - 0.0000139 52.0
PYH2_k127_2897216_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 464.0
PYH2_k127_2897216_10 Cytidylyltransferase K19785 GO:0000309,GO:0001403,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006508,GO:0006511,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007124,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0016049,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019538,GO:0019637,GO:0019674,GO:0019941,GO:0030163,GO:0030433,GO:0030447,GO:0033554,GO:0034356,GO:0034641,GO:0034654,GO:0034976,GO:0036267,GO:0036503,GO:0040007,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043632,GO:0044182,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051603,GO:0051716,GO:0055086,GO:0070566,GO:0070783,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901698 2.7.7.1 0.00000000000000189 85.0
PYH2_k127_2897216_11 SNARE associated Golgi protein - - - 0.000000000001611 74.0
PYH2_k127_2897216_12 sequence-specific DNA binding - - - 0.0007096 52.0
PYH2_k127_2897216_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 447.0
PYH2_k127_2897216_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 398.0
PYH2_k127_2897216_4 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 368.0
PYH2_k127_2897216_5 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 357.0
PYH2_k127_2897216_6 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001328 263.0
PYH2_k127_2897216_7 Domain of unknown function - - - 0.00000000000000000000000000003108 123.0
PYH2_k127_2897216_8 von Willebrand factor, type A K07114 - - 0.00000000000000000000000001144 121.0
PYH2_k127_2897216_9 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000007537 115.0
PYH2_k127_2939973_0 DEAD DEAH box helicase K03724 - - 0.0 1731.0
PYH2_k127_2939973_1 Large extracellular alpha-helical protein K06894 - - 0.0 1487.0
PYH2_k127_2939973_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 619.0
PYH2_k127_2939973_11 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 584.0
PYH2_k127_2939973_12 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 560.0
PYH2_k127_2939973_13 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 515.0
PYH2_k127_2939973_14 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 492.0
PYH2_k127_2939973_15 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 467.0
PYH2_k127_2939973_16 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 484.0
PYH2_k127_2939973_17 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 452.0
PYH2_k127_2939973_18 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 447.0
PYH2_k127_2939973_19 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 425.0
PYH2_k127_2939973_2 metallocarboxypeptidase activity K14054 - - 0.0 1205.0
PYH2_k127_2939973_20 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 416.0
PYH2_k127_2939973_21 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 393.0
PYH2_k127_2939973_22 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 393.0
PYH2_k127_2939973_23 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 383.0
PYH2_k127_2939973_24 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 359.0
PYH2_k127_2939973_25 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 352.0
PYH2_k127_2939973_26 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 346.0
PYH2_k127_2939973_27 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 342.0
PYH2_k127_2939973_28 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 323.0
PYH2_k127_2939973_29 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 339.0
PYH2_k127_2939973_3 Sulfatase K01130 - 3.1.6.1 0.0 1196.0
PYH2_k127_2939973_30 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 316.0
PYH2_k127_2939973_31 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 328.0
PYH2_k127_2939973_32 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 339.0
PYH2_k127_2939973_33 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 299.0
PYH2_k127_2939973_34 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002288 286.0
PYH2_k127_2939973_35 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001575 256.0
PYH2_k127_2939973_36 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
PYH2_k127_2939973_37 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001326 271.0
PYH2_k127_2939973_38 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000004039 246.0
PYH2_k127_2939973_39 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001663 241.0
PYH2_k127_2939973_4 cellulose binding - - - 0.0 1161.0
PYH2_k127_2939973_40 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009841 243.0
PYH2_k127_2939973_41 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000007604 244.0
PYH2_k127_2939973_42 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000002523 251.0
PYH2_k127_2939973_43 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000001245 199.0
PYH2_k127_2939973_44 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000001047 191.0
PYH2_k127_2939973_45 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000000000000000001103 204.0
PYH2_k127_2939973_46 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000004379 185.0
PYH2_k127_2939973_47 Core-2/I-Branching enzyme - - - 0.0000000000000000000000000000000000000000000006907 178.0
PYH2_k127_2939973_48 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000005422 172.0
PYH2_k127_2939973_49 - - - - 0.0000000000000000000000000000000000000000002282 176.0
PYH2_k127_2939973_5 Carboxypeptidase regulatory-like domain - - - 2e-323 1017.0
PYH2_k127_2939973_50 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000001394 163.0
PYH2_k127_2939973_51 PIN domain - - - 0.0000000000000000000000000000000000000002485 153.0
PYH2_k127_2939973_52 PFAM amidohydrolase - - - 0.000000000000000000000000000000000003785 149.0
PYH2_k127_2939973_53 thiolester hydrolase activity - - - 0.0000000000000000000000000000000001052 147.0
PYH2_k127_2939973_54 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.000000000000000000000000000000000144 145.0
PYH2_k127_2939973_55 COGs COG5499 transcription regulator containing HTH domain K18831 - - 0.000000000000000000000000000000002097 133.0
PYH2_k127_2939973_56 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000009607 134.0
PYH2_k127_2939973_58 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000006464 128.0
PYH2_k127_2939973_59 Glycosyl transferases group 1 - - - 0.00000000000000000000000000913 124.0
PYH2_k127_2939973_6 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 8.217e-309 960.0
PYH2_k127_2939973_60 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000001166 111.0
PYH2_k127_2939973_61 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000002253 89.0
PYH2_k127_2939973_62 - - - - 0.0000000000001338 74.0
PYH2_k127_2939973_63 Carboxypeptidase regulatory-like domain - - - 0.00001087 58.0
PYH2_k127_2939973_7 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 3.74e-308 961.0
PYH2_k127_2939973_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.178e-245 785.0
PYH2_k127_2939973_9 Glutamine amidotransferase domain K01953 - 6.3.5.4 2.291e-210 670.0
PYH2_k127_2958207_0 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 9.956e-218 687.0
PYH2_k127_2958207_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 597.0
PYH2_k127_2958207_2 carboxylase K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 416.0
PYH2_k127_2965045_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.438e-264 842.0
PYH2_k127_2965045_1 histidine kinase A domain protein - - - 1.017e-221 725.0
PYH2_k127_2965045_10 F420H(2)-dependent quinone reductase - - - 0.000000000000002829 80.0
PYH2_k127_2965045_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 502.0
PYH2_k127_2965045_3 OmpA family K02557,K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 510.0
PYH2_k127_2965045_4 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000168 216.0
PYH2_k127_2965045_5 TspO/MBR family - - - 0.0000000000000000000000000000000000000000000000000000001863 199.0
PYH2_k127_2965045_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000004349 162.0
PYH2_k127_2965045_7 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000004905 157.0
PYH2_k127_2965045_8 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000004867 139.0
PYH2_k127_2965045_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000074 134.0
PYH2_k127_2965566_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 585.0
PYH2_k127_2965566_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 545.0
PYH2_k127_2965566_10 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 361.0
PYH2_k127_2965566_11 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 325.0
PYH2_k127_2965566_12 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 333.0
PYH2_k127_2965566_13 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 313.0
PYH2_k127_2965566_14 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 308.0
PYH2_k127_2965566_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000004179 218.0
PYH2_k127_2965566_17 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000000001346 168.0
PYH2_k127_2965566_18 BadF BadG BcrA BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000003232 167.0
PYH2_k127_2965566_19 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000005881 148.0
PYH2_k127_2965566_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 531.0
PYH2_k127_2965566_20 positive regulation of MDA-5 signaling pathway - - - 0.000000000000000000005331 103.0
PYH2_k127_2965566_21 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000001322 87.0
PYH2_k127_2965566_23 Protein of unknown function (DUF3311) - - - 0.00000000001654 68.0
PYH2_k127_2965566_24 - - - - 0.0000000005357 67.0
PYH2_k127_2965566_25 Plasmid stabilization system - - - 0.000000001665 59.0
PYH2_k127_2965566_26 Protein of unknown function (DUF433) - - - 0.000000635 57.0
PYH2_k127_2965566_3 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 526.0
PYH2_k127_2965566_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 529.0
PYH2_k127_2965566_5 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 517.0
PYH2_k127_2965566_6 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 505.0
PYH2_k127_2965566_7 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 406.0
PYH2_k127_2965566_8 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 389.0
PYH2_k127_2965566_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 360.0
PYH2_k127_2977428_0 PA domain - - - 4.052e-207 659.0
PYH2_k127_2977428_1 PFAM Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 544.0
PYH2_k127_2977428_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 521.0
PYH2_k127_2977428_3 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006731 266.0
PYH2_k127_2977428_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000001703 177.0
PYH2_k127_2977428_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000001131 167.0
PYH2_k127_2977428_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000005135 161.0
PYH2_k127_2977428_7 amine dehydrogenase activity - - - 0.0000000000000000000000000002098 129.0
PYH2_k127_3008815_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001617 260.0
PYH2_k127_3008815_1 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000005575 252.0
PYH2_k127_3008815_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000005051 202.0
PYH2_k127_3008815_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000002673 124.0
PYH2_k127_3008815_4 Protein of unknown function (DUF3224) - - - 0.00000000000000000006474 93.0
PYH2_k127_3008815_5 - - - - 0.000000000379 63.0
PYH2_k127_3026127_0 Insulinase (Peptidase family M16) K07263 - - 4.32e-266 851.0
PYH2_k127_3026127_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.37e-198 637.0
PYH2_k127_3026127_10 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 303.0
PYH2_k127_3026127_11 oxidoreductase activity K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 311.0
PYH2_k127_3026127_12 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003038 306.0
PYH2_k127_3026127_13 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009058 283.0
PYH2_k127_3026127_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000003245 257.0
PYH2_k127_3026127_15 iron ion homeostasis K02013,K02015 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000008122 252.0
PYH2_k127_3026127_16 Belongs to the glycosyltransferase 26 family K05946,K13660 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
PYH2_k127_3026127_17 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000001258 220.0
PYH2_k127_3026127_18 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000005926 216.0
PYH2_k127_3026127_19 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001181 216.0
PYH2_k127_3026127_2 efflux transmembrane transporter activity - - - 1.715e-197 642.0
PYH2_k127_3026127_20 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000001132 217.0
PYH2_k127_3026127_21 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000006219 190.0
PYH2_k127_3026127_22 PFAM Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000002119 182.0
PYH2_k127_3026127_23 protein-disulfide reductase activity - - - 0.000000000000000000001541 101.0
PYH2_k127_3026127_24 metallopeptidase activity - - - 0.000000000000000003918 88.0
PYH2_k127_3026127_25 domain, Protein K07277,K07278,K21449 - - 0.0000000000000001293 94.0
PYH2_k127_3026127_26 Universal stress protein family - - - 0.00000000000005938 78.0
PYH2_k127_3026127_28 Penicillin - - - 0.000000006882 68.0
PYH2_k127_3026127_29 - - - - 0.00000003584 60.0
PYH2_k127_3026127_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 514.0
PYH2_k127_3026127_30 Putative peptidoglycan binding domain - - - 0.00000003724 63.0
PYH2_k127_3026127_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 465.0
PYH2_k127_3026127_5 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 406.0
PYH2_k127_3026127_6 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 401.0
PYH2_k127_3026127_7 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 376.0
PYH2_k127_3026127_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 364.0
PYH2_k127_3026127_9 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 355.0
PYH2_k127_3061919_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1196.0
PYH2_k127_3061919_1 Tetratricopeptide repeat - - - 0.0 1082.0
PYH2_k127_3061919_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.265e-231 725.0
PYH2_k127_3061919_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 529.0
PYH2_k127_3061919_4 Aminotransferase class-V K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 392.0
PYH2_k127_3061919_5 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 301.0
PYH2_k127_3061919_6 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000225 259.0
PYH2_k127_3071947_0 iron-nicotianamine transmembrane transporter activity - - - 1.255e-286 904.0
PYH2_k127_3071947_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.039e-225 711.0
PYH2_k127_3071947_10 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001194 276.0
PYH2_k127_3071947_11 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000003701 256.0
PYH2_k127_3071947_12 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000003006 172.0
PYH2_k127_3071947_13 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000004957 147.0
PYH2_k127_3071947_14 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000006332 145.0
PYH2_k127_3071947_15 Transcription factor zinc-finger K09981 - - 0.000000000004189 71.0
PYH2_k127_3071947_16 HNH endonuclease - - - 0.00000000115 60.0
PYH2_k127_3071947_17 serine threonine protein kinase K12132 - 2.7.11.1 0.00000918 54.0
PYH2_k127_3071947_18 Protein of unknown function (DUF4231) - - - 0.00008035 51.0
PYH2_k127_3071947_2 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 494.0
PYH2_k127_3071947_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 435.0
PYH2_k127_3071947_4 Abc transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 431.0
PYH2_k127_3071947_5 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 425.0
PYH2_k127_3071947_6 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 431.0
PYH2_k127_3071947_7 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 316.0
PYH2_k127_3071947_8 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 322.0
PYH2_k127_3071947_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 306.0
PYH2_k127_3072577_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 294.0
PYH2_k127_3072577_1 polysaccharide biosynthetic process K06409 - - 0.0000000000000000000000000000000000000000000000000000000000000000003586 247.0
PYH2_k127_3072577_10 Protein of unknown function DUF86 - - - 0.0002223 43.0
PYH2_k127_3072577_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000006857 183.0
PYH2_k127_3072577_3 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000008017 196.0
PYH2_k127_3072577_4 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000002821 181.0
PYH2_k127_3072577_5 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000002927 150.0
PYH2_k127_3072577_6 Domain of unknown function (DUF4926) - - - 0.000000000000000001863 88.0
PYH2_k127_3072577_7 PFAM Fibronectin type III domain - - - 0.0000000000000001871 94.0
PYH2_k127_3072577_8 FG-GAP repeat - - - 0.000002333 61.0
PYH2_k127_3072577_9 metallopeptidase activity - - - 0.00006425 56.0
PYH2_k127_3094146_0 Amidohydrolase family - - - 0.0 1162.0
PYH2_k127_3094146_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 454.0
PYH2_k127_3094146_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 346.0
PYH2_k127_3094146_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 293.0
PYH2_k127_3094146_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005256 248.0
PYH2_k127_3094146_5 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000000000002209 185.0
PYH2_k127_3094146_6 amine dehydrogenase activity - - - 0.000000000000000000000003722 110.0
PYH2_k127_3115340_0 PrkA AAA domain protein K07180 - - 1.058e-298 929.0
PYH2_k127_3115340_1 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 558.0
PYH2_k127_3115340_10 protein N-acetylglucosaminyltransferase activity - - - 0.00000000000003114 87.0
PYH2_k127_3115340_11 gag-polyprotein putative aspartyl protease - - - 0.0001969 49.0
PYH2_k127_3115340_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 558.0
PYH2_k127_3115340_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 499.0
PYH2_k127_3115340_4 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 458.0
PYH2_k127_3115340_5 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 406.0
PYH2_k127_3115340_6 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000003507 230.0
PYH2_k127_3115340_7 Metalloenzyme superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000007911 227.0
PYH2_k127_3115340_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000002855 222.0
PYH2_k127_3115340_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000002908 180.0
PYH2_k127_3191350_0 cellulose binding - - - 0.0 1509.0
PYH2_k127_3191350_1 UvrD/REP helicase N-terminal domain - - - 0.0 1055.0
PYH2_k127_3191350_10 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 523.0
PYH2_k127_3191350_11 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 482.0
PYH2_k127_3191350_12 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 430.0
PYH2_k127_3191350_13 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 359.0
PYH2_k127_3191350_14 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 310.0
PYH2_k127_3191350_15 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
PYH2_k127_3191350_16 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001527 274.0
PYH2_k127_3191350_17 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 263.0
PYH2_k127_3191350_18 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006543 260.0
PYH2_k127_3191350_19 YqcI/YcgG family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006104 253.0
PYH2_k127_3191350_2 DNA polymerase Ligase (LigD) - - - 3.927e-298 934.0
PYH2_k127_3191350_20 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001357 240.0
PYH2_k127_3191350_21 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000001745 207.0
PYH2_k127_3191350_22 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000002808 156.0
PYH2_k127_3191350_23 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000000000000000004575 140.0
PYH2_k127_3191350_24 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000004064 122.0
PYH2_k127_3191350_25 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000009792 123.0
PYH2_k127_3191350_26 Putative restriction endonuclease - - - 0.00000000000000000000000000002751 118.0
PYH2_k127_3191350_27 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000003484 117.0
PYH2_k127_3191350_28 - - - - 0.0000000000000000000000002627 111.0
PYH2_k127_3191350_29 ThiS family K03636 - - 0.000000000000000000000003896 104.0
PYH2_k127_3191350_3 PD-(D/E)XK nuclease superfamily - - - 4.287e-296 945.0
PYH2_k127_3191350_30 PFAM Plasmid stabilisation system protein K19092 - - 0.000000000000000001209 90.0
PYH2_k127_3191350_31 PFAM Archaeal ATPase - - - 0.000000000000000002767 95.0
PYH2_k127_3191350_32 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000005476 96.0
PYH2_k127_3191350_33 Fe2 transport system protein A K04758 - - 0.000000000001075 70.0
PYH2_k127_3191350_34 - - - - 0.00000000004577 64.0
PYH2_k127_3191350_35 COGs COG4636 conserved - - - 0.000000001158 59.0
PYH2_k127_3191350_37 COGs COG4636 conserved - - - 0.00007774 45.0
PYH2_k127_3191350_38 - - - - 0.0002429 45.0
PYH2_k127_3191350_4 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence - - - 2.356e-198 630.0
PYH2_k127_3191350_40 Pentapeptide repeats (9 copies) - - - 0.0007442 43.0
PYH2_k127_3191350_5 transmembrane transporter activity K08196 - - 9.734e-196 619.0
PYH2_k127_3191350_6 protein related to plant photosystem II stability assembly factor - - - 2.879e-194 614.0
PYH2_k127_3191350_7 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 605.0
PYH2_k127_3191350_8 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 581.0
PYH2_k127_3191350_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 571.0
PYH2_k127_3199015_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.246e-269 849.0
PYH2_k127_3199015_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 535.0
PYH2_k127_3199015_2 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 417.0
PYH2_k127_3199015_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 339.0
PYH2_k127_3199015_4 COGs COG4636 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002136 252.0
PYH2_k127_3199015_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003261 246.0
PYH2_k127_3199015_6 NUDIX domain - - - 0.0000000000000000000000000006125 118.0
PYH2_k127_3199015_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000001372 105.0
PYH2_k127_3199015_8 Domain of unknown function (DUF5117) - - - 0.00004451 51.0
PYH2_k127_3258203_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.561e-213 680.0
PYH2_k127_3258203_1 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 3.068e-207 667.0
PYH2_k127_3258203_10 - K06921 - - 0.0000000000000000000000000000000000005153 151.0
PYH2_k127_3258203_11 PFAM Abortive infection protein K07052 - - 0.0000000000000000000002096 106.0
PYH2_k127_3258203_13 Glycosyl transferase - - - 0.0002964 44.0
PYH2_k127_3258203_14 nuclear chromosome segregation - - - 0.0006003 48.0
PYH2_k127_3258203_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 499.0
PYH2_k127_3258203_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 430.0
PYH2_k127_3258203_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 368.0
PYH2_k127_3258203_5 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008762 255.0
PYH2_k127_3258203_6 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.00000000000000000000000000000000000000000000000000000000000000000843 241.0
PYH2_k127_3258203_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002613 235.0
PYH2_k127_3258203_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000145 228.0
PYH2_k127_3258203_9 DoxX - - - 0.0000000000000000000000000000000000001803 144.0
PYH2_k127_3266790_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1215.0
PYH2_k127_3266790_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1029.0
PYH2_k127_3266790_10 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 561.0
PYH2_k127_3266790_11 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 404.0
PYH2_k127_3266790_12 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 397.0
PYH2_k127_3266790_13 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 374.0
PYH2_k127_3266790_14 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 370.0
PYH2_k127_3266790_15 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 365.0
PYH2_k127_3266790_16 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 334.0
PYH2_k127_3266790_17 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
PYH2_k127_3266790_18 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000001221 222.0
PYH2_k127_3266790_19 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000003601 119.0
PYH2_k127_3266790_2 TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 2.115e-321 998.0
PYH2_k127_3266790_20 diguanylate cyclase - - - 0.000000000000000000001526 95.0
PYH2_k127_3266790_21 Putative restriction endonuclease - - - 0.000146 48.0
PYH2_k127_3266790_3 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 5.315e-267 839.0
PYH2_k127_3266790_4 Glycogen debranching enzyme K05989 - 3.2.1.40 1.139e-262 838.0
PYH2_k127_3266790_5 Beta-L-arabinofuranosidase, GH127 K09955 - - 1.019e-221 704.0
PYH2_k127_3266790_6 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.708e-201 644.0
PYH2_k127_3266790_7 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 1.334e-197 630.0
PYH2_k127_3266790_8 isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 605.0
PYH2_k127_3266790_9 Coagulation factor 5 8 type domain protein K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 584.0
PYH2_k127_3353942_0 cytochrome c peroxidase K00428 - 1.11.1.5 1.706e-237 758.0
PYH2_k127_3353942_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 548.0
PYH2_k127_3353942_10 Protein of unknown function (DUF969) - - - 0.000000000000000000000000000000000000000000000000000656 194.0
PYH2_k127_3353942_12 blue (type 1) copper K00368 - 1.7.2.1 0.0000000000000000000009083 101.0
PYH2_k127_3353942_13 Peptidase family M28 - - - 0.00000000000000005309 83.0
PYH2_k127_3353942_15 PFAM blue (type 1) copper domain protein - - - 0.000000000005985 75.0
PYH2_k127_3353942_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 539.0
PYH2_k127_3353942_3 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 500.0
PYH2_k127_3353942_4 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 505.0
PYH2_k127_3353942_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 371.0
PYH2_k127_3353942_6 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 369.0
PYH2_k127_3353942_7 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 296.0
PYH2_k127_3353942_8 Protein of unknown function (DUF979) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002834 256.0
PYH2_k127_3353942_9 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000002767 228.0
PYH2_k127_3367964_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1379.0
PYH2_k127_3367964_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.553e-205 647.0
PYH2_k127_3367964_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 342.0
PYH2_k127_3367964_11 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 332.0
PYH2_k127_3367964_12 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 322.0
PYH2_k127_3367964_13 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 314.0
PYH2_k127_3367964_14 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 332.0
PYH2_k127_3367964_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 325.0
PYH2_k127_3367964_16 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 288.0
PYH2_k127_3367964_17 protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
PYH2_k127_3367964_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000004079 235.0
PYH2_k127_3367964_19 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000002811 224.0
PYH2_k127_3367964_2 glutamine synthetase K01915 - 6.3.1.2 4.668e-201 636.0
PYH2_k127_3367964_21 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.000000000000000000000000000000000000000002786 160.0
PYH2_k127_3367964_22 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000001145 145.0
PYH2_k127_3367964_23 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000006237 145.0
PYH2_k127_3367964_24 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000001422 137.0
PYH2_k127_3367964_25 Endoribonuclease L-PSP - - - 0.00000000000000000000000002652 113.0
PYH2_k127_3367964_26 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000002407 110.0
PYH2_k127_3367964_27 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001207 109.0
PYH2_k127_3367964_28 Pkd domain containing protein - - - 0.0000000000000000000006579 112.0
PYH2_k127_3367964_29 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000001148 111.0
PYH2_k127_3367964_3 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 600.0
PYH2_k127_3367964_30 imidazolonepropionase activity - - - 0.000000000000000000002592 100.0
PYH2_k127_3367964_31 Protein of unknown function (DUF2892) - - - 0.00000000000000005094 83.0
PYH2_k127_3367964_32 Protein tyrosine kinase - - - 0.00000000000000192 82.0
PYH2_k127_3367964_33 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000009422 78.0
PYH2_k127_3367964_35 Protein conserved in bacteria - - - 0.000000009582 61.0
PYH2_k127_3367964_37 Cupin domain - - - 0.000001913 57.0
PYH2_k127_3367964_38 Protein of unknown function (DUF1573) - - - 0.0002198 49.0
PYH2_k127_3367964_39 self proteolysis - - - 0.0007662 50.0
PYH2_k127_3367964_4 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 518.0
PYH2_k127_3367964_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 492.0
PYH2_k127_3367964_6 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 458.0
PYH2_k127_3367964_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 420.0
PYH2_k127_3367964_8 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 400.0
PYH2_k127_3367964_9 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 386.0
PYH2_k127_3558428_0 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 552.0
PYH2_k127_3558428_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 472.0
PYH2_k127_3558428_10 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000007593 126.0
PYH2_k127_3558428_11 Regulatory protein, FmdB family - - - 0.00000000000000000002712 92.0
PYH2_k127_3558428_12 Lysin motif - - - 0.000000000000000002269 89.0
PYH2_k127_3558428_13 Peptidase, M16 K07263 - - 0.00000000000003405 80.0
PYH2_k127_3558428_14 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000004701 70.0
PYH2_k127_3558428_15 transglycosylase associated protein - - - 0.00000001899 57.0
PYH2_k127_3558428_16 Transglycosylase associated protein - - - 0.00001963 47.0
PYH2_k127_3558428_17 BON domain K04065 - - 0.0003108 48.0
PYH2_k127_3558428_18 methylated-DNA-protein-cysteine S-methyltransferase Ogt - - - 0.000729 44.0
PYH2_k127_3558428_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 427.0
PYH2_k127_3558428_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 403.0
PYH2_k127_3558428_4 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 393.0
PYH2_k127_3558428_5 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000004511 275.0
PYH2_k127_3558428_6 Acyl dehydratase - - - 0.000000000000000000000000000000000000000000000000007498 184.0
PYH2_k127_3558428_7 dehydratase - - - 0.0000000000000000000000000000000000000000000004488 177.0
PYH2_k127_3558428_8 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000273 168.0
PYH2_k127_3558428_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000001211 156.0
PYH2_k127_3807993_0 Carboxypeptidase regulatory-like domain - - - 2.78e-235 746.0
PYH2_k127_3807993_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000005574 246.0
PYH2_k127_3807993_2 Penicillin amidase K07116 - 3.5.1.97 0.0000000000000000000001209 102.0
PYH2_k127_3807993_3 TonB dependent receptor - - - 0.0000178 56.0
PYH2_k127_3807993_4 Tetratricopeptide repeat - - - 0.000227 53.0
PYH2_k127_3822160_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.379e-264 828.0
PYH2_k127_3822160_1 Putative diguanylate phosphodiesterase - - - 1.181e-210 680.0
PYH2_k127_3822160_10 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003104 254.0
PYH2_k127_3822160_11 MerR HTH family regulatory protein K13640 - - 0.00000000000000000000000000000000002697 138.0
PYH2_k127_3822160_12 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000007373 118.0
PYH2_k127_3822160_13 Ankyrin repeat - - - 0.000000000000000001024 92.0
PYH2_k127_3822160_14 Peptidase, S54 (Rhomboid) family - - - 0.0000000000000002883 93.0
PYH2_k127_3822160_2 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 612.0
PYH2_k127_3822160_3 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 538.0
PYH2_k127_3822160_4 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 446.0
PYH2_k127_3822160_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 413.0
PYH2_k127_3822160_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 392.0
PYH2_k127_3822160_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 348.0
PYH2_k127_3822160_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001745 287.0
PYH2_k127_3822160_9 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004919 266.0
PYH2_k127_3822869_0 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 460.0
PYH2_k127_3822869_1 - - - - 0.000000000000000000000000000000000000000000000000000002465 205.0
PYH2_k127_3822869_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0001385 46.0
PYH2_k127_3872618_0 Peptidase M14, carboxypeptidase A - - - 0.0 1508.0
PYH2_k127_3872618_1 choline dehydrogenase activity - - - 6.409e-300 928.0
PYH2_k127_3872618_10 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 366.0
PYH2_k127_3872618_11 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 326.0
PYH2_k127_3872618_12 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000008668 256.0
PYH2_k127_3872618_13 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000454 209.0
PYH2_k127_3872618_14 dioxygenase activity K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000006486 199.0
PYH2_k127_3872618_15 - - - - 0.000000000000000000000000000000000000000000000000001057 189.0
PYH2_k127_3872618_16 COG1228 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000105 181.0
PYH2_k127_3872618_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000005779 158.0
PYH2_k127_3872618_19 OsmC-like protein - - - 0.0000000000000000000000000000000000182 139.0
PYH2_k127_3872618_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 8.015e-219 688.0
PYH2_k127_3872618_20 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000123 135.0
PYH2_k127_3872618_21 DinB superfamily - - - 0.000000000000000000000000000000005902 136.0
PYH2_k127_3872618_22 - - - - 0.000000000000000000000000000001713 123.0
PYH2_k127_3872618_23 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000008978 119.0
PYH2_k127_3872618_24 von Willebrand factor type A domain K07114 - - 0.000000000000002465 87.0
PYH2_k127_3872618_25 Protein of unknown function (DUF433) - - - 0.0000000000000117 75.0
PYH2_k127_3872618_26 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000008865 76.0
PYH2_k127_3872618_27 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000008659 75.0
PYH2_k127_3872618_28 -Thioesterase K01075 - 3.1.2.23 0.00000000003562 71.0
PYH2_k127_3872618_29 Helix-turn-helix XRE-family like proteins K18831 - - 0.0000000008418 59.0
PYH2_k127_3872618_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.502e-216 698.0
PYH2_k127_3872618_30 PFAM Plasmid stabilisation system protein - - - 0.000000007452 64.0
PYH2_k127_3872618_31 Sporulation related domain - - - 0.000005049 59.0
PYH2_k127_3872618_32 - - - - 0.0001781 50.0
PYH2_k127_3872618_4 NADH oxidase - - - 2.863e-211 666.0
PYH2_k127_3872618_5 Sugar (and other) transporter K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 428.0
PYH2_k127_3872618_6 PFAM Transketolase central region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 423.0
PYH2_k127_3872618_7 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 405.0
PYH2_k127_3872618_8 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 398.0
PYH2_k127_3872618_9 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 385.0
PYH2_k127_3995570_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1032.0
PYH2_k127_3995570_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 441.0
PYH2_k127_3995570_10 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000001647 168.0
PYH2_k127_3995570_11 - - - - 0.0000000000000000000000000000000000000000001817 171.0
PYH2_k127_3995570_12 Two component regulator propeller - - - 0.00000000000000000000000000000000000000001468 177.0
PYH2_k127_3995570_13 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000002417 159.0
PYH2_k127_3995570_14 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000251 162.0
PYH2_k127_3995570_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000001165 146.0
PYH2_k127_3995570_16 - - - - 0.00000000000002328 78.0
PYH2_k127_3995570_17 Protein of unknown function (DUF3142) - - - 0.00000000002166 77.0
PYH2_k127_3995570_18 Phosphopantetheine attachment site - - - 0.00000000006164 65.0
PYH2_k127_3995570_19 - - - - 0.00000002158 58.0
PYH2_k127_3995570_2 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 421.0
PYH2_k127_3995570_20 - - - - 0.00000004673 64.0
PYH2_k127_3995570_21 Putative zinc-finger - - - 0.00005682 53.0
PYH2_k127_3995570_22 - - - - 0.00008538 56.0
PYH2_k127_3995570_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 362.0
PYH2_k127_3995570_4 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 326.0
PYH2_k127_3995570_5 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 307.0
PYH2_k127_3995570_6 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000001958 244.0
PYH2_k127_3995570_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000003143 233.0
PYH2_k127_3995570_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000008406 214.0
PYH2_k127_3995570_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000006016 186.0
PYH2_k127_3995735_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1289.0
PYH2_k127_3995735_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 547.0
PYH2_k127_3995735_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
PYH2_k127_3995735_11 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000000000000007015 151.0
PYH2_k127_3995735_12 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000000000001147 127.0
PYH2_k127_3995735_13 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000005777 118.0
PYH2_k127_3995735_14 Domain of unknown function (DUF4160) - - - 0.0000000000000000000000000004646 115.0
PYH2_k127_3995735_15 DNA-binding transcription factor activity K15973 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000006171 98.0
PYH2_k127_3995735_16 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000003135 90.0
PYH2_k127_3995735_17 membrane - - - 0.0000000000000001998 95.0
PYH2_k127_3995735_18 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000003598 73.0
PYH2_k127_3995735_2 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 477.0
PYH2_k127_3995735_3 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 446.0
PYH2_k127_3995735_4 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 427.0
PYH2_k127_3995735_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 353.0
PYH2_k127_3995735_6 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 330.0
PYH2_k127_3995735_7 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 324.0
PYH2_k127_3995735_8 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 317.0
PYH2_k127_3995735_9 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000152 277.0
PYH2_k127_4012851_0 transport - - - 1.113e-312 992.0
PYH2_k127_4012851_1 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 4.683e-203 647.0
PYH2_k127_4012851_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000002499 89.0
PYH2_k127_4012851_11 - - - - 0.000000000125 68.0
PYH2_k127_4012851_12 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000132 63.0
PYH2_k127_4012851_13 Sodium/calcium exchanger protein K07300 - - 0.00000000602 57.0
PYH2_k127_4012851_14 Belongs to the amidase family K01426 - 3.5.1.4 0.00000004055 62.0
PYH2_k127_4012851_15 Tetratricopeptide TPR_2 repeat protein - - - 0.000002494 59.0
PYH2_k127_4012851_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K07263 - - 0.000007471 57.0
PYH2_k127_4012851_2 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 492.0
PYH2_k127_4012851_3 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 392.0
PYH2_k127_4012851_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 384.0
PYH2_k127_4012851_5 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000006161 217.0
PYH2_k127_4012851_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000009118 201.0
PYH2_k127_4012851_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000002069 147.0
PYH2_k127_4012851_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000002883 146.0
PYH2_k127_4012851_9 Helix-turn-helix domain - - - 0.00000000000000000000001333 105.0
PYH2_k127_4024102_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 352.0
PYH2_k127_4024102_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004531 261.0
PYH2_k127_4127559_0 Sortilin, neurotensin receptor 3, - - - 0.0 1491.0
PYH2_k127_4127559_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 564.0
PYH2_k127_4127559_10 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000006981 239.0
PYH2_k127_4127559_11 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000004161 215.0
PYH2_k127_4127559_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000001998 211.0
PYH2_k127_4127559_13 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000001352 203.0
PYH2_k127_4127559_14 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000003553 153.0
PYH2_k127_4127559_15 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000001432 127.0
PYH2_k127_4127559_16 - - - - 0.000000000000000000000009317 108.0
PYH2_k127_4127559_2 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 507.0
PYH2_k127_4127559_3 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 447.0
PYH2_k127_4127559_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 409.0
PYH2_k127_4127559_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 321.0
PYH2_k127_4127559_6 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
PYH2_k127_4127559_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 265.0
PYH2_k127_4127559_8 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
PYH2_k127_4127559_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000001422 224.0
PYH2_k127_4144793_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2732.0
PYH2_k127_4144793_1 Amidohydrolase family - - - 1.512e-299 957.0
PYH2_k127_4144793_10 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 349.0
PYH2_k127_4144793_11 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 344.0
PYH2_k127_4144793_12 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 332.0
PYH2_k127_4144793_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 317.0
PYH2_k127_4144793_14 Carboxypeptidase regulatory-like domain K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006135 291.0
PYH2_k127_4144793_15 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000002105 252.0
PYH2_k127_4144793_16 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000137 192.0
PYH2_k127_4144793_17 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000003921 164.0
PYH2_k127_4144793_18 - - - - 0.000000000000000000000000000000000006597 138.0
PYH2_k127_4144793_19 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000003996 132.0
PYH2_k127_4144793_2 Carboxyl transferase domain - - - 2.44e-221 697.0
PYH2_k127_4144793_20 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000438 138.0
PYH2_k127_4144793_21 Belongs to the ompA family - - - 0.000000000000000006748 96.0
PYH2_k127_4144793_23 Protein of unknown function (DUF3500) - - - 0.0000000006944 63.0
PYH2_k127_4144793_24 - - - - 0.000000009433 66.0
PYH2_k127_4144793_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 563.0
PYH2_k127_4144793_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 466.0
PYH2_k127_4144793_5 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 431.0
PYH2_k127_4144793_6 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 409.0
PYH2_k127_4144793_7 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 380.0
PYH2_k127_4144793_8 Aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 363.0
PYH2_k127_4144793_9 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 372.0
PYH2_k127_4164275_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.378e-299 932.0
PYH2_k127_4164275_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 7.272e-277 856.0
PYH2_k127_4164275_10 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 448.0
PYH2_k127_4164275_11 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 428.0
PYH2_k127_4164275_12 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 421.0
PYH2_k127_4164275_13 Bacterial extracellular solute-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 406.0
PYH2_k127_4164275_14 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 402.0
PYH2_k127_4164275_15 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 399.0
PYH2_k127_4164275_16 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 403.0
PYH2_k127_4164275_17 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 373.0
PYH2_k127_4164275_18 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 350.0
PYH2_k127_4164275_19 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 312.0
PYH2_k127_4164275_2 heat shock protein 70 K04043,K04044 - - 3.319e-223 707.0
PYH2_k127_4164275_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 286.0
PYH2_k127_4164275_21 TIGRFAM sulfate ABC transporter K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 293.0
PYH2_k127_4164275_22 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 288.0
PYH2_k127_4164275_23 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001381 293.0
PYH2_k127_4164275_24 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005588 274.0
PYH2_k127_4164275_25 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003418 269.0
PYH2_k127_4164275_26 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001503 252.0
PYH2_k127_4164275_27 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000001019 246.0
PYH2_k127_4164275_28 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000001639 240.0
PYH2_k127_4164275_29 PFAM YdjC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001308 237.0
PYH2_k127_4164275_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 603.0
PYH2_k127_4164275_30 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000461 239.0
PYH2_k127_4164275_31 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000004142 226.0
PYH2_k127_4164275_32 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
PYH2_k127_4164275_33 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000000000000002379 200.0
PYH2_k127_4164275_34 Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family K05928 - 2.1.1.95 0.0000000000000000000000000000000000000000000000000000005985 203.0
PYH2_k127_4164275_35 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
PYH2_k127_4164275_36 phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000002049 201.0
PYH2_k127_4164275_37 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000007357 185.0
PYH2_k127_4164275_38 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000158 192.0
PYH2_k127_4164275_39 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000000000000000000004106 186.0
PYH2_k127_4164275_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 593.0
PYH2_k127_4164275_40 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000002955 172.0
PYH2_k127_4164275_41 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.000000000000000000000000000000000000001371 151.0
PYH2_k127_4164275_42 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000156 150.0
PYH2_k127_4164275_43 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000002732 137.0
PYH2_k127_4164275_44 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000008685 137.0
PYH2_k127_4164275_45 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000004112 132.0
PYH2_k127_4164275_46 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000009151 127.0
PYH2_k127_4164275_47 Fe-S cluster K04488 - - 0.0000000000000000000000000004898 117.0
PYH2_k127_4164275_48 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000004184 108.0
PYH2_k127_4164275_49 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000007244 104.0
PYH2_k127_4164275_5 Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 537.0
PYH2_k127_4164275_50 nuclear chromosome segregation - - - 0.0000000000000000000006314 109.0
PYH2_k127_4164275_51 Iron-sulphur cluster assembly - - - 0.0000000000000000000007188 99.0
PYH2_k127_4164275_52 C4-type zinc ribbon domain K07164 - - 0.000000000000000000005373 104.0
PYH2_k127_4164275_53 Cupin - - - 0.000000000000000002116 93.0
PYH2_k127_4164275_54 Domain of unknown function (DUF4139) - - - 0.0000000000000003162 91.0
PYH2_k127_4164275_55 PFAM helix-turn-helix, Fis-type - - - 0.000000003279 61.0
PYH2_k127_4164275_56 - - - - 0.0000005911 59.0
PYH2_k127_4164275_57 PFAM Colicin V production protein K03558 - - 0.000000998 58.0
PYH2_k127_4164275_58 PFAM sigma-70 region 2 domain protein K03088 - - 0.000003873 57.0
PYH2_k127_4164275_59 Tetratricopeptide repeat - - - 0.000008183 57.0
PYH2_k127_4164275_6 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 509.0
PYH2_k127_4164275_60 Involved in the tonB-independent uptake of proteins - - - 0.00002622 58.0
PYH2_k127_4164275_61 - - - - 0.00006941 51.0
PYH2_k127_4164275_62 Domain of unknown function DUF87 - - - 0.0001778 53.0
PYH2_k127_4164275_63 Tetratricopeptide repeat - - - 0.0002485 53.0
PYH2_k127_4164275_64 - K06950 - - 0.0004873 46.0
PYH2_k127_4164275_65 Double zinc ribbon - - - 0.0009785 50.0
PYH2_k127_4164275_7 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 481.0
PYH2_k127_4164275_8 DNA polymerase K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 456.0
PYH2_k127_4164275_9 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 446.0
PYH2_k127_4171031_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 457.0
PYH2_k127_4171031_1 tigr00255 - - - 0.000000000000000000000000000000000000000000000000000000000006492 218.0
PYH2_k127_4171031_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000246 204.0
PYH2_k127_4171031_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000004677 155.0
PYH2_k127_4171031_4 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00000003729 57.0
PYH2_k127_4180044_0 Tricorn protease PDZ domain K08676 - - 0.0 1365.0
PYH2_k127_4180044_1 Tricorn protease PDZ domain K08676 - - 0.0 1337.0
PYH2_k127_4180044_10 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000001327 263.0
PYH2_k127_4180044_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 263.0
PYH2_k127_4180044_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000002158 194.0
PYH2_k127_4180044_13 Probable molybdopterin binding domain K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000531 183.0
PYH2_k127_4180044_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000000001395 174.0
PYH2_k127_4180044_15 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.0000000000000000000000000000000000000009038 164.0
PYH2_k127_4180044_16 PFAM Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000006108 152.0
PYH2_k127_4180044_17 AI-2E family transporter - - - 0.0000000000000000000000000000000002347 147.0
PYH2_k127_4180044_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000006137 132.0
PYH2_k127_4180044_19 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.000000000006146 78.0
PYH2_k127_4180044_2 domain protein - - - 1.344e-237 779.0
PYH2_k127_4180044_21 Two component signalling adaptor domain K03408 - - 0.0000411 52.0
PYH2_k127_4180044_22 AhpC/TSA family - - - 0.00005225 54.0
PYH2_k127_4180044_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 587.0
PYH2_k127_4180044_4 Domain of unknown function (DUF3471) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 532.0
PYH2_k127_4180044_5 COGs COG2382 Enterochelin esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 443.0
PYH2_k127_4180044_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 353.0
PYH2_k127_4180044_7 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 327.0
PYH2_k127_4180044_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 340.0
PYH2_k127_4180044_9 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 341.0
PYH2_k127_4258815_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1033.0
PYH2_k127_4258815_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.462e-316 986.0
PYH2_k127_4258815_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 452.0
PYH2_k127_4258815_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 328.0
PYH2_k127_4258815_4 membrane - - - 0.00000000000000000000000000000000000000003334 158.0
PYH2_k127_4258815_5 - - - - 0.000000000000000000000000000001584 135.0
PYH2_k127_4258815_6 type IV pilus secretin PilQ K02666 - - 0.000000000000004011 89.0
PYH2_k127_4258815_7 Pilus assembly protein, PilO K02664 - - 0.0000001573 61.0
PYH2_k127_4264285_0 serine threonine protein kinase K12132 - 2.7.11.1 1.226e-233 752.0
PYH2_k127_4264285_1 metallopeptidase activity - - - 8.363e-212 676.0
PYH2_k127_4264285_10 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001717 261.0
PYH2_k127_4264285_11 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 237.0
PYH2_k127_4264285_12 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000004512 234.0
PYH2_k127_4264285_13 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000004933 254.0
PYH2_k127_4264285_14 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000001435 227.0
PYH2_k127_4264285_16 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000001029 200.0
PYH2_k127_4264285_17 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000000000000001666 197.0
PYH2_k127_4264285_18 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000004532 175.0
PYH2_k127_4264285_19 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000002694 170.0
PYH2_k127_4264285_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 406.0
PYH2_k127_4264285_20 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000000000005344 164.0
PYH2_k127_4264285_21 Multicopper oxidase K22350 - 1.16.3.3 0.0000000000000000000000000000004094 143.0
PYH2_k127_4264285_23 FHA domain - - - 0.00000000000000000296 94.0
PYH2_k127_4264285_24 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000009069 83.0
PYH2_k127_4264285_25 PEGA domain - - - 0.00000000005027 75.0
PYH2_k127_4264285_26 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000002074 71.0
PYH2_k127_4264285_27 Dystroglycan-type cadherin-like domains. - - - 0.0000000003443 74.0
PYH2_k127_4264285_3 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 356.0
PYH2_k127_4264285_4 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 327.0
PYH2_k127_4264285_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 349.0
PYH2_k127_4264285_6 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 320.0
PYH2_k127_4264285_7 PFAM ABC transporter related K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 314.0
PYH2_k127_4264285_8 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 310.0
PYH2_k127_4264285_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 278.0
PYH2_k127_433073_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.247e-276 860.0
PYH2_k127_433073_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 574.0
PYH2_k127_433073_10 PHP domain protein K02347 - - 0.0000000000000000000000000000000000003081 146.0
PYH2_k127_433073_11 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000001292 134.0
PYH2_k127_433073_12 - - - - 0.000000000000000000001786 109.0
PYH2_k127_433073_13 von Willebrand factor, type A K07114 - - 0.00000000000000000004222 103.0
PYH2_k127_433073_14 oxidoreductase activity K12511 - - 0.000000000000000001382 99.0
PYH2_k127_433073_15 TM2 domain - - - 0.000000000002873 74.0
PYH2_k127_433073_16 Tetratricopeptide repeat - - - 0.00000003783 64.0
PYH2_k127_433073_17 - - - - 0.000001682 59.0
PYH2_k127_433073_18 HEPN domain - - - 0.0001944 45.0
PYH2_k127_433073_2 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 426.0
PYH2_k127_433073_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 411.0
PYH2_k127_433073_4 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 327.0
PYH2_k127_433073_5 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002786 273.0
PYH2_k127_433073_6 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000008339 223.0
PYH2_k127_433073_7 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000009195 194.0
PYH2_k127_433073_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000003355 202.0
PYH2_k127_433073_9 Isochorismatase family - - - 0.000000000000000000000000000000000000003428 153.0
PYH2_k127_4340248_0 cellulose binding - - - 0.0 1464.0
PYH2_k127_4340248_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1025.0
PYH2_k127_4340248_10 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
PYH2_k127_4340248_11 PFAM Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000001279 249.0
PYH2_k127_4340248_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000001344 213.0
PYH2_k127_4340248_13 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000003647 225.0
PYH2_k127_4340248_14 - K00241 - - 0.0000000000000000000000000000000000000000000000000000009588 201.0
PYH2_k127_4340248_15 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000001148 147.0
PYH2_k127_4340248_16 Beta-lactamase - - - 0.0000000000000000000000000000000000001239 162.0
PYH2_k127_4340248_17 Peptidase M23 K21471 - - 0.000000000000000000000000000000004994 139.0
PYH2_k127_4340248_18 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000009371 140.0
PYH2_k127_4340248_19 - - - - 0.000000000000000000000000000005081 121.0
PYH2_k127_4340248_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 3.35e-233 744.0
PYH2_k127_4340248_20 Rhodanese Homology Domain - - - 0.0000000000000000000000000002256 121.0
PYH2_k127_4340248_21 - - - - 0.000000000000000000000000008429 123.0
PYH2_k127_4340248_22 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001211 108.0
PYH2_k127_4340248_23 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000004018 108.0
PYH2_k127_4340248_24 Chitinase class I - - - 0.00000000000000000000004414 105.0
PYH2_k127_4340248_25 AAA domain - - - 0.0000000000006031 71.0
PYH2_k127_4340248_26 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.00000000002602 65.0
PYH2_k127_4340248_27 Protein of unknown function (DUF3108) - - - 0.000000004942 66.0
PYH2_k127_4340248_3 Amidohydrolase family - - - 3.266e-197 631.0
PYH2_k127_4340248_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.209e-194 635.0
PYH2_k127_4340248_5 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 515.0
PYH2_k127_4340248_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
PYH2_k127_4340248_7 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 362.0
PYH2_k127_4340248_8 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 341.0
PYH2_k127_4340248_9 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 300.0
PYH2_k127_4360698_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 460.0
PYH2_k127_4360698_1 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 454.0
PYH2_k127_4360698_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 355.0
PYH2_k127_4360698_3 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 346.0
PYH2_k127_4360698_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000001359 196.0
PYH2_k127_4360698_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000005564 164.0
PYH2_k127_4360698_6 C-terminal domain of histone - - - 0.0000000000000000000000000000000000000000205 158.0
PYH2_k127_4360698_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000003781 98.0
PYH2_k127_4360698_8 ECF sigma factor - - - 0.0000002742 54.0
PYH2_k127_436167_0 Protein of unknown function, DUF255 K06888 - - 3.133e-243 769.0
PYH2_k127_436167_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 593.0
PYH2_k127_436167_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000002719 159.0
PYH2_k127_436167_11 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000001074 169.0
PYH2_k127_436167_12 alcohol dehydrogenase K00001,K13953,K13979 - 1.1.1.1 0.0000000000000000000000000000001114 128.0
PYH2_k127_436167_13 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000109 120.0
PYH2_k127_436167_14 YbbR-like protein - - - 0.0000008233 60.0
PYH2_k127_436167_15 - - - - 0.000007621 56.0
PYH2_k127_436167_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 566.0
PYH2_k127_436167_3 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 426.0
PYH2_k127_436167_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 410.0
PYH2_k127_436167_5 alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 390.0
PYH2_k127_436167_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 394.0
PYH2_k127_436167_7 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
PYH2_k127_436167_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000103 220.0
PYH2_k127_436167_9 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001603 171.0
PYH2_k127_4385807_0 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 556.0
PYH2_k127_4385807_1 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 390.0
PYH2_k127_44247_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 502.0
PYH2_k127_44247_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 421.0
PYH2_k127_44247_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 357.0
PYH2_k127_44247_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 310.0
PYH2_k127_44247_4 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000001143 192.0
PYH2_k127_44247_5 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000000000001849 190.0
PYH2_k127_44247_6 Peptidase, M16 K07263 - - 0.000000000000000000000000003951 120.0
PYH2_k127_4477653_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.062e-212 671.0
PYH2_k127_4477653_1 Periplasmic protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 554.0
PYH2_k127_4477653_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 290.0
PYH2_k127_4477653_11 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000002819 258.0
PYH2_k127_4477653_12 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002917 273.0
PYH2_k127_4477653_13 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.000000000000000000000000000000000000000000000000000144 192.0
PYH2_k127_4477653_14 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000002456 162.0
PYH2_k127_4477653_15 NIPSNAP family containing protein - - - 0.0000000000000000000000000000000000003232 145.0
PYH2_k127_4477653_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000005859 82.0
PYH2_k127_4477653_2 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 490.0
PYH2_k127_4477653_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 462.0
PYH2_k127_4477653_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 430.0
PYH2_k127_4477653_5 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 413.0
PYH2_k127_4477653_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 342.0
PYH2_k127_4477653_7 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 327.0
PYH2_k127_4477653_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 314.0
PYH2_k127_4477653_9 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 296.0
PYH2_k127_4491856_0 Dienelactone hydrolase family - - - 0.0 1172.0
PYH2_k127_4491856_1 C-terminal, D2-small domain, of ClpB protein K11907 - - 8.157e-306 952.0
PYH2_k127_4491856_10 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 495.0
PYH2_k127_4491856_11 type VI secretion protein K11900,K11901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 473.0
PYH2_k127_4491856_12 PFAM PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 489.0
PYH2_k127_4491856_13 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 354.0
PYH2_k127_4491856_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 332.0
PYH2_k127_4491856_15 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 314.0
PYH2_k127_4491856_16 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001771 267.0
PYH2_k127_4491856_17 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 258.0
PYH2_k127_4491856_18 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006184 253.0
PYH2_k127_4491856_19 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000001045 241.0
PYH2_k127_4491856_2 Phosphoglucose isomerase K01810 - 5.3.1.9 3.392e-299 925.0
PYH2_k127_4491856_20 Pfam:Methyltransf_26 K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000007558 238.0
PYH2_k127_4491856_21 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000004817 218.0
PYH2_k127_4491856_23 Domain of unknown function (DUF4123) - - - 0.000000000000000000000000000000000000000000108 168.0
PYH2_k127_4491856_24 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000001836 159.0
PYH2_k127_4491856_25 Domain of unknown function (DUF4123) - - - 0.00000000000000003243 87.0
PYH2_k127_4491856_26 TIGRFAM Na H antiporter, bacterial form K03316 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - 0.0000000000000001782 81.0
PYH2_k127_4491856_27 Putative esterase K07017 - - 0.000000000000001728 89.0
PYH2_k127_4491856_28 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000168 69.0
PYH2_k127_4491856_29 - - - - 0.00000000003246 72.0
PYH2_k127_4491856_3 repeat protein - - - 5.524e-286 892.0
PYH2_k127_4491856_30 ADP-ribosylglycohydrolase - - - 0.00000000003592 73.0
PYH2_k127_4491856_31 Domain of unknown function (DUF1906) - - - 0.0000000001052 72.0
PYH2_k127_4491856_32 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.0000000007082 61.0
PYH2_k127_4491856_33 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15 0.000000001712 68.0
PYH2_k127_4491856_34 COG0025 NhaP-type Na H and K H antiporters K03316 - - 0.00000000188 63.0
PYH2_k127_4491856_35 peptidase S9 - - - 0.00000001096 67.0
PYH2_k127_4491856_36 Bacterial protein of unknown function (DUF922) - - - 0.00001139 54.0
PYH2_k127_4491856_37 Beta-galactosidase, domain 3 - - - 0.00001259 51.0
PYH2_k127_4491856_38 - - - - 0.00001584 57.0
PYH2_k127_4491856_39 PAAR motif - - - 0.00007723 49.0
PYH2_k127_4491856_4 ATPase involved in DNA repair - - - 5.381e-281 901.0
PYH2_k127_4491856_40 CoA binding domain - - - 0.0002075 48.0
PYH2_k127_4491856_5 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 5.689e-229 718.0
PYH2_k127_4491856_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.944e-202 646.0
PYH2_k127_4491856_7 Rhs Element Vgr Protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 619.0
PYH2_k127_4491856_8 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 569.0
PYH2_k127_4491856_9 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 548.0
PYH2_k127_4523410_0 cellulose binding - - - 0.0 1147.0
PYH2_k127_4523410_1 Response regulator receiver - - - 6.12e-203 640.0
PYH2_k127_4523410_10 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 297.0
PYH2_k127_4523410_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 295.0
PYH2_k127_4523410_12 PFAM Calcineurin-like phosphoesterase K07099 - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 241.0
PYH2_k127_4523410_13 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008016 233.0
PYH2_k127_4523410_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000001214 233.0
PYH2_k127_4523410_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000009183 223.0
PYH2_k127_4523410_16 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000005171 209.0
PYH2_k127_4523410_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000001879 208.0
PYH2_k127_4523410_18 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000005761 213.0
PYH2_k127_4523410_19 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.0000000000000000000000000000000000000000000000000003238 191.0
PYH2_k127_4523410_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.715e-201 631.0
PYH2_k127_4523410_20 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000005916 184.0
PYH2_k127_4523410_21 nucleotide catabolic process - - - 0.0000000000000000000000000000000002543 147.0
PYH2_k127_4523410_22 Putative Ig domain - - - 0.0000000000000000000000000000000006178 142.0
PYH2_k127_4523410_23 overlaps another CDS with the same product name K07263,K07623 - - 0.00000000000000000000000000000001041 143.0
PYH2_k127_4523410_24 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000001163 144.0
PYH2_k127_4523410_25 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000002016 133.0
PYH2_k127_4523410_27 Anti-sigma-K factor RskA - - - 0.00000000000000000001515 102.0
PYH2_k127_4523410_28 Belongs to the 'phage' integrase family K04763 - - 0.000000000001533 73.0
PYH2_k127_4523410_29 Putative restriction endonuclease - - - 0.00000001974 58.0
PYH2_k127_4523410_3 Protein of unknown function (DUF1254) - - - 5.008e-198 619.0
PYH2_k127_4523410_30 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000006176 57.0
PYH2_k127_4523410_31 - - - - 0.00003726 47.0
PYH2_k127_4523410_4 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 598.0
PYH2_k127_4523410_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 564.0
PYH2_k127_4523410_6 Spermidine putrescine-binding periplasmic protein K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 491.0
PYH2_k127_4523410_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 442.0
PYH2_k127_4523410_8 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 435.0
PYH2_k127_4523410_9 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 381.0
PYH2_k127_4601288_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 519.0
PYH2_k127_4601288_1 histone H2A K63-linked ubiquitination K03220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 501.0
PYH2_k127_4601288_10 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000000000000000000000001868 218.0
PYH2_k127_4601288_11 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000004527 156.0
PYH2_k127_4601288_12 Major facilitator superfamily - - - 0.00000000000000000000000000000000000006337 157.0
PYH2_k127_4601288_13 - - - - 0.0000000000000000000003547 102.0
PYH2_k127_4601288_14 Transcriptional regulator, Crp Fnr family K10914,K21564,K22490 GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009416,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019216,GO:0019219,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0042803,GO:0045828,GO:0045834,GO:0045893,GO:0045935,GO:0046889,GO:0046890,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071214,GO:0071478,GO:0071482,GO:0080090,GO:0097159,GO:0104004,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1904143,GO:2000112,GO:2001141 - 0.0000000000000000000009418 105.0
PYH2_k127_4601288_15 PBS lyase HEAT-like repeat - - - 0.000000000000002894 85.0
PYH2_k127_4601288_16 Prokaryotic N-terminal methylation motif K02650 - - 0.0000002242 58.0
PYH2_k127_4601288_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 381.0
PYH2_k127_4601288_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 338.0
PYH2_k127_4601288_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 312.0
PYH2_k127_4601288_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 310.0
PYH2_k127_4601288_6 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 305.0
PYH2_k127_4601288_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004996 293.0
PYH2_k127_4601288_8 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007378 286.0
PYH2_k127_4601288_9 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002661 276.0
PYH2_k127_4614426_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 577.0
PYH2_k127_4614426_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 511.0
PYH2_k127_4614426_10 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000001293 111.0
PYH2_k127_4614426_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000001108 106.0
PYH2_k127_4614426_12 - - - - 0.00000000000000000000004642 102.0
PYH2_k127_4614426_13 hyperosmotic response K04065 - - 0.000000000000000003991 94.0
PYH2_k127_4614426_14 Prokaryotic N-terminal methylation motif K02650 - - 0.0009086 50.0
PYH2_k127_4614426_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 373.0
PYH2_k127_4614426_3 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 357.0
PYH2_k127_4614426_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 334.0
PYH2_k127_4614426_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001732 282.0
PYH2_k127_4614426_6 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001095 251.0
PYH2_k127_4614426_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
PYH2_k127_4614426_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000004817 145.0
PYH2_k127_4614426_9 - - - - 0.0000000000000000000000000164 113.0
PYH2_k127_4650595_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 5.968e-218 694.0
PYH2_k127_4650595_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 537.0
PYH2_k127_4650595_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000001314 151.0
PYH2_k127_4650595_11 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000001038 144.0
PYH2_k127_4650595_12 Methyltransferase type 11 - - - 0.000000000000000000000000000000002682 143.0
PYH2_k127_4650595_13 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000001577 126.0
PYH2_k127_4650595_14 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000001814 126.0
PYH2_k127_4650595_15 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000002837 91.0
PYH2_k127_4650595_17 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000001638 65.0
PYH2_k127_4650595_18 Tetratricopeptide repeat - - - 0.0000001851 63.0
PYH2_k127_4650595_19 HNH endonuclease - - - 0.0000005834 52.0
PYH2_k127_4650595_2 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 472.0
PYH2_k127_4650595_20 AAA ATPase domain - - - 0.0003298 53.0
PYH2_k127_4650595_3 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
PYH2_k127_4650595_4 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 345.0
PYH2_k127_4650595_5 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001039 296.0
PYH2_k127_4650595_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004862 279.0
PYH2_k127_4650595_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003477 269.0
PYH2_k127_4650595_8 PFAM Cupin domain - - - 0.00000000000000000000000000000000000000000000000001215 182.0
PYH2_k127_4650595_9 -O-antigen - - - 0.0000000000000000000000000000000000000000000000007168 192.0
PYH2_k127_4654027_0 FAD binding domain K07077 - - 1.884e-205 651.0
PYH2_k127_4654027_1 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 610.0
PYH2_k127_4654027_2 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 477.0
PYH2_k127_4654027_3 Sir2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 322.0
PYH2_k127_4654027_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001482 293.0
PYH2_k127_4654027_5 - - - - 0.000000000000000000000000003533 115.0
PYH2_k127_4654027_6 Dehydrogenase K07077 - - 0.00000000009533 63.0
PYH2_k127_4654027_7 Cytochrome c554 and c-prime - - - 0.000009714 56.0
PYH2_k127_4688840_0 serine threonine protein kinase K12132 - 2.7.11.1 3.427e-209 680.0
PYH2_k127_4688840_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 492.0
PYH2_k127_4688840_10 metallopeptidase activity - - - 0.0004918 50.0
PYH2_k127_4688840_2 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 435.0
PYH2_k127_4688840_3 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 356.0
PYH2_k127_4688840_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000004922 208.0
PYH2_k127_4688840_5 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000003387 134.0
PYH2_k127_4688840_6 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000003069 132.0
PYH2_k127_4688840_7 YwiC-like protein - - - 0.000000000000000001158 95.0
PYH2_k127_4688840_8 PFAM Nitrate reductase delta subunit - - - 0.000000000000000001357 95.0
PYH2_k127_4688840_9 cAMP biosynthetic process - - - 0.00001661 47.0
PYH2_k127_4723979_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.104e-248 776.0
PYH2_k127_4723979_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.796e-246 771.0
PYH2_k127_4723979_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008636 269.0
PYH2_k127_4723979_11 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000286 203.0
PYH2_k127_4723979_12 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000008499 201.0
PYH2_k127_4723979_13 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000006666 184.0
PYH2_k127_4723979_14 PFAM Nickel cobalt transporter, high-affinity - - - 0.00000000000000000000000000000000000000000003144 169.0
PYH2_k127_4723979_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000002155 140.0
PYH2_k127_4723979_16 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000000003118 136.0
PYH2_k127_4723979_17 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000001514 142.0
PYH2_k127_4723979_18 TPM domain K06872 - - 0.0000000000000000000000000227 121.0
PYH2_k127_4723979_19 - - - - 0.0000000000000000000000001931 113.0
PYH2_k127_4723979_2 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 4.413e-217 683.0
PYH2_k127_4723979_20 PFAM multicopper oxidase type K08100 - 1.3.3.5 0.0000000000000000001211 101.0
PYH2_k127_4723979_21 - - - - 0.0000000147 63.0
PYH2_k127_4723979_22 - - - - 0.0003742 52.0
PYH2_k127_4723979_3 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 511.0
PYH2_k127_4723979_4 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 469.0
PYH2_k127_4723979_5 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 455.0
PYH2_k127_4723979_6 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 451.0
PYH2_k127_4723979_7 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 447.0
PYH2_k127_4723979_8 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 370.0
PYH2_k127_4723979_9 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009315 285.0
PYH2_k127_4737992_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.797e-208 660.0
PYH2_k127_4737992_1 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 540.0
PYH2_k127_4737992_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000003113 231.0
PYH2_k127_4737992_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000007721 173.0
PYH2_k127_4752119_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2015.0
PYH2_k127_4752119_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1479.0
PYH2_k127_4752119_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000004491 134.0
PYH2_k127_4752119_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000004631 92.0
PYH2_k127_4752119_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000005509 84.0
PYH2_k127_4752119_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000002172 72.0
PYH2_k127_4752119_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0003054 47.0
PYH2_k127_4752119_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.835e-284 887.0
PYH2_k127_4752119_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 560.0
PYH2_k127_4752119_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 304.0
PYH2_k127_4752119_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002285 233.0
PYH2_k127_4752119_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000001215 220.0
PYH2_k127_4752119_7 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000004933 218.0
PYH2_k127_4752119_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH2_k127_4752119_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000005685 154.0
PYH2_k127_4827517_0 Peptidase family M1 domain - - - 5.577e-236 741.0
PYH2_k127_4827517_1 Asparagine synthase K01953 - 6.3.5.4 2.71e-216 688.0
PYH2_k127_4827517_10 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.00000000000000000000000000000000000000000000000000000000001819 221.0
PYH2_k127_4827517_11 - - - - 0.00000000000000000000000000000000000000000001471 169.0
PYH2_k127_4827517_12 response to abiotic stimulus - - - 0.000000000000003885 76.0
PYH2_k127_4827517_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000004444 65.0
PYH2_k127_4827517_14 - - - - 0.00000001492 65.0
PYH2_k127_4827517_2 Peptidase dimerisation domain - - - 1.018e-205 651.0
PYH2_k127_4827517_3 Penicillin amidase - - - 4.029e-194 610.0
PYH2_k127_4827517_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 589.0
PYH2_k127_4827517_5 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 516.0
PYH2_k127_4827517_6 response to abiotic stimulus K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 436.0
PYH2_k127_4827517_7 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 415.0
PYH2_k127_4827517_8 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 355.0
PYH2_k127_4827517_9 DNA topoisomerase VI subunit A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001179 282.0
PYH2_k127_4843372_0 Sortilin, neurotensin receptor 3, - - - 0.0 1433.0
PYH2_k127_4843372_1 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1245.0
PYH2_k127_4843372_10 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000005803 216.0
PYH2_k127_4843372_11 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000005909 205.0
PYH2_k127_4843372_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000006976 186.0
PYH2_k127_4843372_13 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000001735 156.0
PYH2_k127_4843372_14 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000000000000002485 135.0
PYH2_k127_4843372_15 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000007632 116.0
PYH2_k127_4843372_16 - - - - 0.0000000000000000000002271 106.0
PYH2_k127_4843372_17 nucleic acid-binding protein - - - 0.00000000000009752 75.0
PYH2_k127_4843372_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000007848 70.0
PYH2_k127_4843372_19 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000001004 72.0
PYH2_k127_4843372_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 585.0
PYH2_k127_4843372_20 - - - - 0.00000009868 60.0
PYH2_k127_4843372_21 - - - - 0.000006386 53.0
PYH2_k127_4843372_22 Uncharacterised protein family (UPF0175) - - - 0.00002419 46.0
PYH2_k127_4843372_23 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0001627 48.0
PYH2_k127_4843372_3 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 578.0
PYH2_k127_4843372_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 454.0
PYH2_k127_4843372_5 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 465.0
PYH2_k127_4843372_6 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 461.0
PYH2_k127_4843372_7 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 436.0
PYH2_k127_4843372_8 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 351.0
PYH2_k127_4843372_9 cell shape determining protein, MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 292.0
PYH2_k127_4844360_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 9.546e-231 726.0
PYH2_k127_4844360_1 aminopeptidase activity - - - 2.284e-194 619.0
PYH2_k127_4844360_10 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000006499 148.0
PYH2_k127_4844360_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000006317 64.0
PYH2_k127_4844360_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000008622 60.0
PYH2_k127_4844360_13 - - - - 0.0008962 48.0
PYH2_k127_4844360_2 glutamate decarboxylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 593.0
PYH2_k127_4844360_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 556.0
PYH2_k127_4844360_4 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 421.0
PYH2_k127_4844360_5 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 359.0
PYH2_k127_4844360_6 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 351.0
PYH2_k127_4844360_7 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001566 299.0
PYH2_k127_4844360_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000001228 242.0
PYH2_k127_4844360_9 Belongs to the ompA family - - - 0.0000000000000000000000000000000000005102 149.0
PYH2_k127_4852151_0 amino acid transport K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 500.0
PYH2_k127_4852151_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 479.0
PYH2_k127_4852151_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 407.0
PYH2_k127_4852151_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005647 273.0
PYH2_k127_4898040_0 Tricorn protease homolog - - - 0.0 1376.0
PYH2_k127_4898040_1 Heparinase II/III N-terminus - - - 6.345e-276 867.0
PYH2_k127_4898040_10 Belongs to the ABC transporter superfamily K10112,K17240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 380.0
PYH2_k127_4898040_11 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
PYH2_k127_4898040_12 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 304.0
PYH2_k127_4898040_13 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 291.0
PYH2_k127_4898040_14 Bacterial sugar transferase K19428 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001254 276.0
PYH2_k127_4898040_15 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004286 276.0
PYH2_k127_4898040_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000007114 261.0
PYH2_k127_4898040_17 PFAM Xylose isomerase domain protein TIM barrel K06606 - 5.3.99.11 0.00000000000000000000000000000000000000000000000000000000000002625 224.0
PYH2_k127_4898040_18 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000305 239.0
PYH2_k127_4898040_19 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000702 196.0
PYH2_k127_4898040_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.888e-244 762.0
PYH2_k127_4898040_20 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000622 180.0
PYH2_k127_4898040_21 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000003538 176.0
PYH2_k127_4898040_22 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000001686 148.0
PYH2_k127_4898040_23 Methyltransferase domain - - - 0.0000000000000000000000000000001038 132.0
PYH2_k127_4898040_24 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000569 126.0
PYH2_k127_4898040_25 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000002189 122.0
PYH2_k127_4898040_3 Carbamoyltransferase C-terminus K00612 - - 3.961e-238 752.0
PYH2_k127_4898040_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 546.0
PYH2_k127_4898040_5 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 507.0
PYH2_k127_4898040_6 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 466.0
PYH2_k127_4898040_7 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 454.0
PYH2_k127_4898040_8 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 445.0
PYH2_k127_4898040_9 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 397.0
PYH2_k127_4898327_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1282.0
PYH2_k127_4898327_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.052e-279 878.0
PYH2_k127_4898327_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000205 297.0
PYH2_k127_4898327_11 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000034 229.0
PYH2_k127_4898327_12 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000005866 119.0
PYH2_k127_4898327_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000476 102.0
PYH2_k127_4898327_14 - - - - 0.0000009148 59.0
PYH2_k127_4898327_2 glycolate transport K14393 - - 2.672e-237 744.0
PYH2_k127_4898327_3 Prolyl oligopeptidase family - - - 9.177e-230 730.0
PYH2_k127_4898327_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 598.0
PYH2_k127_4898327_5 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 373.0
PYH2_k127_4898327_6 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 356.0
PYH2_k127_4898327_7 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 354.0
PYH2_k127_4898327_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 298.0
PYH2_k127_4898327_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 295.0
PYH2_k127_4984950_0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0 1065.0
PYH2_k127_4984950_1 ATPase family associated with various cellular activities (AAA) - - - 7.491e-216 689.0
PYH2_k127_4984950_2 RimK-like ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 380.0
PYH2_k127_4984950_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 387.0
PYH2_k127_4984950_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 352.0
PYH2_k127_4984950_5 - - - - 0.00000000000000000000000000000000000000000000000000000005654 211.0
PYH2_k127_5052796_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.051e-214 677.0
PYH2_k127_5052796_1 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 470.0
PYH2_k127_5052796_10 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000003265 210.0
PYH2_k127_5052796_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000838 203.0
PYH2_k127_5052796_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000006038 175.0
PYH2_k127_5052796_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000003414 163.0
PYH2_k127_5052796_14 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000006252 91.0
PYH2_k127_5052796_15 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000007464 88.0
PYH2_k127_5052796_16 Tfp pilus assembly protein FimV - - - 0.000005759 57.0
PYH2_k127_5052796_2 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 468.0
PYH2_k127_5052796_3 nuclease activity - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 379.0
PYH2_k127_5052796_4 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 373.0
PYH2_k127_5052796_5 PFAM Basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
PYH2_k127_5052796_6 Transporter-associated region K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 358.0
PYH2_k127_5052796_7 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 353.0
PYH2_k127_5052796_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000001817 214.0
PYH2_k127_5052796_9 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000002435 217.0
PYH2_k127_5098395_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1313.0
PYH2_k127_5098395_1 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 589.0
PYH2_k127_5098395_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000007381 149.0
PYH2_k127_5098395_11 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000000000001118 147.0
PYH2_k127_5098395_12 protein conserved in cyanobacteria - - - 0.0000000000000000000000000001738 119.0
PYH2_k127_5098395_13 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000001718 117.0
PYH2_k127_5098395_14 amine dehydrogenase activity - - - 0.0001133 50.0
PYH2_k127_5098395_2 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 516.0
PYH2_k127_5098395_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 392.0
PYH2_k127_5098395_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 351.0
PYH2_k127_5098395_5 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 331.0
PYH2_k127_5098395_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 323.0
PYH2_k127_5098395_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 317.0
PYH2_k127_5098395_8 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
PYH2_k127_5098395_9 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000183 203.0
PYH2_k127_5112275_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0 1022.0
PYH2_k127_5112275_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 3.974e-225 716.0
PYH2_k127_5112275_10 PFAM Binding-protein-dependent transport system inner membrane component K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 303.0
PYH2_k127_5112275_11 PFAM Binding-protein-dependent transport system inner membrane component K02025,K17242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
PYH2_k127_5112275_12 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000009593 261.0
PYH2_k127_5112275_13 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.00000000002669 65.0
PYH2_k127_5112275_15 PFAM Tetratricopeptide repeat - - - 0.0006436 46.0
PYH2_k127_5112275_2 PFAM Glycosyl hydrolases family 31 K01187 - 3.2.1.20 4.887e-203 660.0
PYH2_k127_5112275_3 MFS/sugar transport protein K16211 - - 4.551e-200 633.0
PYH2_k127_5112275_4 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 584.0
PYH2_k127_5112275_5 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 432.0
PYH2_k127_5112275_6 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 394.0
PYH2_k127_5112275_7 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 326.0
PYH2_k127_5112275_8 Glycogen debranching enzyme, glucanotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 330.0
PYH2_k127_5112275_9 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 316.0
PYH2_k127_5137514_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1137.0
PYH2_k127_5137514_1 Flavin containing amine oxidoreductase - - - 9.776e-218 689.0
PYH2_k127_5137514_10 enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000009927 216.0
PYH2_k127_5137514_11 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000002462 212.0
PYH2_k127_5137514_12 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000003423 198.0
PYH2_k127_5137514_13 Membrane - - - 0.0000000000000000000000000000000000000000000000001441 191.0
PYH2_k127_5137514_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000007359 184.0
PYH2_k127_5137514_15 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000007621 152.0
PYH2_k127_5137514_16 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000003079 147.0
PYH2_k127_5137514_17 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000006306 147.0
PYH2_k127_5137514_18 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000004909 138.0
PYH2_k127_5137514_19 Protein of unknown function (DUF1572) - - - 0.00000000000000000000004477 107.0
PYH2_k127_5137514_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 541.0
PYH2_k127_5137514_20 Outer membrane efflux protein K15725 - - 0.000000000000000000009325 106.0
PYH2_k127_5137514_22 Cupredoxin-like domain - - - 0.000000000000002558 90.0
PYH2_k127_5137514_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000003478 72.0
PYH2_k127_5137514_24 helix_turn_helix, arabinose operon control protein - - - 0.0000001598 59.0
PYH2_k127_5137514_25 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0001073 46.0
PYH2_k127_5137514_26 Multicopper oxidase - - - 0.0003443 52.0
PYH2_k127_5137514_3 PFAM aldo keto reductase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 530.0
PYH2_k127_5137514_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 416.0
PYH2_k127_5137514_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 425.0
PYH2_k127_5137514_6 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 384.0
PYH2_k127_5137514_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000002485 253.0
PYH2_k127_5137514_8 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000001412 239.0
PYH2_k127_5137514_9 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
PYH2_k127_517124_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 3.862e-268 845.0
PYH2_k127_517124_1 Domain of unknown function (DUF5117) - - - 3.025e-248 792.0
PYH2_k127_517124_10 acetyltransferase - - - 0.00000000000000000000000000001188 132.0
PYH2_k127_517124_11 - - - - 0.0000000000000000000001143 104.0
PYH2_k127_517124_12 heat shock protein binding - - - 0.00000000000005698 82.0
PYH2_k127_517124_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 617.0
PYH2_k127_517124_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 408.0
PYH2_k127_517124_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 377.0
PYH2_k127_517124_5 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
PYH2_k127_517124_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000002892 219.0
PYH2_k127_517124_7 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000001566 201.0
PYH2_k127_517124_8 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000003769 167.0
PYH2_k127_517124_9 CHRD domain - - - 0.000000000000000000000000000000000000171 147.0
PYH2_k127_5172619_0 Tricorn protease homolog K08676 - - 0.0 1546.0
PYH2_k127_5172619_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.098e-236 743.0
PYH2_k127_5172619_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 382.0
PYH2_k127_5172619_11 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 364.0
PYH2_k127_5172619_12 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 349.0
PYH2_k127_5172619_13 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 346.0
PYH2_k127_5172619_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 323.0
PYH2_k127_5172619_15 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 319.0
PYH2_k127_5172619_16 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 305.0
PYH2_k127_5172619_17 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 296.0
PYH2_k127_5172619_18 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 294.0
PYH2_k127_5172619_19 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005403 287.0
PYH2_k127_5172619_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 598.0
PYH2_k127_5172619_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002422 279.0
PYH2_k127_5172619_21 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002652 276.0
PYH2_k127_5172619_22 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004373 273.0
PYH2_k127_5172619_23 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000003475 263.0
PYH2_k127_5172619_24 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001228 256.0
PYH2_k127_5172619_25 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000003598 238.0
PYH2_k127_5172619_26 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000002535 227.0
PYH2_k127_5172619_27 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000001059 209.0
PYH2_k127_5172619_28 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000003034 199.0
PYH2_k127_5172619_29 PFAM peptidylprolyl isomerase FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000004555 172.0
PYH2_k127_5172619_3 PFAM Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 553.0
PYH2_k127_5172619_30 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000632 162.0
PYH2_k127_5172619_31 reductase K00059 - 1.1.1.100 0.0000000000000000000000007347 115.0
PYH2_k127_5172619_32 Trm112p-like protein K09791 - - 0.000000000000000000000005576 102.0
PYH2_k127_5172619_33 Phosphocarrier protein HPr K08485,K11189 - - 0.000000000000000000006394 100.0
PYH2_k127_5172619_34 ubiE/COQ5 methyltransferase family - - - 0.0000000000001097 82.0
PYH2_k127_5172619_35 alkylhydroperoxidase like protein, AhpD family - - - 0.000000003614 63.0
PYH2_k127_5172619_36 TIGRFAM TonB family protein K03832 - - 0.0000002605 62.0
PYH2_k127_5172619_37 Glycosyl transferase family 41 - - - 0.0000671 52.0
PYH2_k127_5172619_38 - - - - 0.0001524 52.0
PYH2_k127_5172619_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 553.0
PYH2_k127_5172619_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 526.0
PYH2_k127_5172619_6 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 512.0
PYH2_k127_5172619_7 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 454.0
PYH2_k127_5172619_8 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 449.0
PYH2_k127_5172619_9 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 434.0
PYH2_k127_5178486_0 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000004626 201.0
PYH2_k127_5178486_1 Fibronectin-binding A domain protein - - - 0.00000000000000000000000000000000000000000000000001571 200.0
PYH2_k127_5178486_2 Tetratricopeptide repeat - - - 0.0000000000000000000008228 111.0
PYH2_k127_5211917_0 Peptidase M14, carboxypeptidase A - - - 0.0 1133.0
PYH2_k127_5211917_1 serine-type peptidase activity - - - 5.591e-316 985.0
PYH2_k127_5211917_2 Protein of unknown function DUF262 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 411.0
PYH2_k127_5211917_3 - - - - 0.00000000000000000000000000000000000000000000002515 174.0
PYH2_k127_5211917_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000001438 138.0
PYH2_k127_5211917_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000004869 119.0
PYH2_k127_5226011_0 Cysteine-rich domain K00113 - 1.1.5.3 7.515e-214 672.0
PYH2_k127_5226011_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 598.0
PYH2_k127_5226011_10 Domain of unknown function (DUF4276) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 288.0
PYH2_k127_5226011_11 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001414 261.0
PYH2_k127_5226011_12 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000001286 225.0
PYH2_k127_5226011_13 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000007206 227.0
PYH2_k127_5226011_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000002799 228.0
PYH2_k127_5226011_15 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000001978 201.0
PYH2_k127_5226011_16 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000005502 187.0
PYH2_k127_5226011_17 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000002127 188.0
PYH2_k127_5226011_18 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000006538 138.0
PYH2_k127_5226011_19 Belongs to the Fur family - - - 0.00000000000000000000000008212 113.0
PYH2_k127_5226011_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 522.0
PYH2_k127_5226011_20 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.000000000000003404 80.0
PYH2_k127_5226011_21 Belongs to the UPF0102 family K07460 - - 0.0000000000000351 79.0
PYH2_k127_5226011_3 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 514.0
PYH2_k127_5226011_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 448.0
PYH2_k127_5226011_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 425.0
PYH2_k127_5226011_6 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 396.0
PYH2_k127_5226011_7 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 375.0
PYH2_k127_5226011_8 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 362.0
PYH2_k127_5226011_9 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 304.0
PYH2_k127_5250210_0 PPE family K02453,K02484,K03732,K03980,K12065 - 2.7.13.3,3.6.4.13 6.259e-212 679.0
PYH2_k127_5250210_1 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000005904 94.0
PYH2_k127_5284122_0 PFAM NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 611.0
PYH2_k127_5284122_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 436.0
PYH2_k127_5284122_10 - - - - 0.000000000000001044 82.0
PYH2_k127_5284122_11 - - - - 0.00000000000004276 85.0
PYH2_k127_5284122_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000003533 80.0
PYH2_k127_5284122_13 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000001438 70.0
PYH2_k127_5284122_14 - - - - 0.00000001169 64.0
PYH2_k127_5284122_15 Putative restriction endonuclease - - - 0.000001322 53.0
PYH2_k127_5284122_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 307.0
PYH2_k127_5284122_3 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001375 275.0
PYH2_k127_5284122_4 Probable molybdopterin binding domain K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
PYH2_k127_5284122_5 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000007499 237.0
PYH2_k127_5284122_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000124 237.0
PYH2_k127_5284122_7 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000002103 184.0
PYH2_k127_5284122_8 DoxX-like family - - - 0.000000000000000000000000000000001597 134.0
PYH2_k127_5284122_9 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000006268 127.0
PYH2_k127_5286918_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 581.0
PYH2_k127_5286918_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 371.0
PYH2_k127_5286918_10 Polysaccharide deacetylase - - - 0.00000000000000000005688 102.0
PYH2_k127_5286918_11 Ribosomal L32p protein family K02911 - - 0.0000000000000000000575 90.0
PYH2_k127_5286918_12 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000006571 78.0
PYH2_k127_5286918_13 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000001266 75.0
PYH2_k127_5286918_14 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00003925 56.0
PYH2_k127_5286918_2 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 327.0
PYH2_k127_5286918_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000001568 223.0
PYH2_k127_5286918_4 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000002947 188.0
PYH2_k127_5286918_5 PFAM Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.000000000000000000000000000000000009619 151.0
PYH2_k127_5286918_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000007312 138.0
PYH2_k127_5286918_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000009557 132.0
PYH2_k127_5286918_8 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000004146 117.0
PYH2_k127_5286918_9 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000816 97.0
PYH2_k127_5331963_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.817e-223 704.0
PYH2_k127_5331963_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 630.0
PYH2_k127_5331963_10 Alpha beta hydrolase fold protein - - - 0.00000000000000000000000000000000000000000000000000002089 198.0
PYH2_k127_5331963_11 - - - - 0.00000000000000000000000000000000000000000000001609 182.0
PYH2_k127_5331963_12 Putative zinc ribbon domain - - - 0.0000000000000000000000000000000000000001329 151.0
PYH2_k127_5331963_14 Phosphoglycerate mutase - - - 0.00000000000000000000000000004941 125.0
PYH2_k127_5331963_15 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000007969 106.0
PYH2_k127_5331963_16 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.000000001891 71.0
PYH2_k127_5331963_17 - - - - 0.0000003296 57.0
PYH2_k127_5331963_18 PhoQ Sensor - - - 0.000001433 62.0
PYH2_k127_5331963_2 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 517.0
PYH2_k127_5331963_3 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 400.0
PYH2_k127_5331963_4 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 310.0
PYH2_k127_5331963_5 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 294.0
PYH2_k127_5331963_6 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000009591 259.0
PYH2_k127_5331963_7 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007281 250.0
PYH2_k127_5331963_8 PFAM intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000001719 224.0
PYH2_k127_5331963_9 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000005991 216.0
PYH2_k127_5370955_0 R3H domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 594.0
PYH2_k127_5370955_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 476.0
PYH2_k127_5370955_2 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 395.0
PYH2_k127_5370955_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 349.0
PYH2_k127_5370955_4 protein secretion K02460 - - 0.0000000000000000000000659 115.0
PYH2_k127_5370955_5 Pkd domain containing protein - - - 0.000000000000000002225 100.0
PYH2_k127_5370955_6 acetyltransferase K06976 - - 0.00000000000000003635 92.0
PYH2_k127_5370955_7 - - - - 0.000000000103 72.0
PYH2_k127_5370955_8 type IV pilus modification protein PilV K02458,K02671 - - 0.00001124 55.0
PYH2_k127_5370955_9 Type IV Pilus-assembly protein W K02672 - - 0.0003116 53.0
PYH2_k127_5458000_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 535.0
PYH2_k127_5458000_1 LUD domain K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 470.0
PYH2_k127_5458000_2 LUD domain K00782 - - 0.000000000000000000000000000000008945 136.0
PYH2_k127_54987_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1320.0
PYH2_k127_54987_1 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 0.0 1039.0
PYH2_k127_54987_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001383 258.0
PYH2_k127_54987_11 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003523 259.0
PYH2_k127_54987_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009766 275.0
PYH2_k127_54987_13 XdhC Rossmann domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001433 252.0
PYH2_k127_54987_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000007029 223.0
PYH2_k127_54987_15 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000006334 213.0
PYH2_k127_54987_16 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000001409 214.0
PYH2_k127_54987_17 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000001538 187.0
PYH2_k127_54987_18 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000000000000000000000002472 179.0
PYH2_k127_54987_19 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000001375 166.0
PYH2_k127_54987_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 446.0
PYH2_k127_54987_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000365 152.0
PYH2_k127_54987_21 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000007574 140.0
PYH2_k127_54987_22 TIR domain - - - 0.000000000000000000000000000000000007989 149.0
PYH2_k127_54987_23 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000001617 121.0
PYH2_k127_54987_24 PFAM peptidase S16 lon domain protein K07157 - - 0.00000000000000000000002353 110.0
PYH2_k127_54987_25 DNA-templated transcription, initiation K03088 - - 0.0000000000000005478 87.0
PYH2_k127_54987_26 Glycosyltransferase family 87 - - - 0.0000000000001015 83.0
PYH2_k127_54987_28 Bifunctional sulfur carrier protein thiazole synthase K03154 - - 0.00000000000155 69.0
PYH2_k127_54987_29 - - - - 0.00000000000192 78.0
PYH2_k127_54987_3 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 402.0
PYH2_k127_54987_30 O-Antigen ligase K18814 - - 0.00000003322 66.0
PYH2_k127_54987_31 - - - - 0.0001212 48.0
PYH2_k127_54987_4 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 440.0
PYH2_k127_54987_5 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 374.0
PYH2_k127_54987_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 351.0
PYH2_k127_54987_7 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 333.0
PYH2_k127_54987_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 308.0
PYH2_k127_54987_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007825 253.0
PYH2_k127_5554087_0 Carboxypeptidase regulatory-like domain - - - 2.945e-248 804.0
PYH2_k127_5554087_1 AAA domain - - - 6.344e-207 675.0
PYH2_k127_5554087_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 437.0
PYH2_k127_5554087_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 411.0
PYH2_k127_5554087_12 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 429.0
PYH2_k127_5554087_13 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 407.0
PYH2_k127_5554087_14 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 365.0
PYH2_k127_5554087_15 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 348.0
PYH2_k127_5554087_16 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 335.0
PYH2_k127_5554087_17 Alkaline phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 327.0
PYH2_k127_5554087_18 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 317.0
PYH2_k127_5554087_19 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 318.0
PYH2_k127_5554087_2 Ribosomal protein S1 K02945 - - 1.071e-202 650.0
PYH2_k127_5554087_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003043 268.0
PYH2_k127_5554087_21 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
PYH2_k127_5554087_22 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000009842 228.0
PYH2_k127_5554087_23 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000006522 211.0
PYH2_k127_5554087_24 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000005778 211.0
PYH2_k127_5554087_25 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000001604 184.0
PYH2_k127_5554087_26 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000001825 157.0
PYH2_k127_5554087_27 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000000000000000004536 146.0
PYH2_k127_5554087_28 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000167 149.0
PYH2_k127_5554087_29 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000003198 119.0
PYH2_k127_5554087_3 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 495.0
PYH2_k127_5554087_30 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000001109 98.0
PYH2_k127_5554087_31 - - - - 0.00000000000000003129 91.0
PYH2_k127_5554087_32 Cupin 2, conserved barrel domain protein - - - 0.0000000000000008811 79.0
PYH2_k127_5554087_33 Putative transmembrane protein (PGPGW) - - - 0.000000000000006708 79.0
PYH2_k127_5554087_34 - - - - 0.00000003448 65.0
PYH2_k127_5554087_35 Protein of unknown function (DUF3341) - - - 0.000002183 55.0
PYH2_k127_5554087_36 peptidyl-tyrosine sulfation - - - 0.000177 55.0
PYH2_k127_5554087_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 485.0
PYH2_k127_5554087_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 456.0
PYH2_k127_5554087_6 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 455.0
PYH2_k127_5554087_7 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 449.0
PYH2_k127_5554087_8 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 472.0
PYH2_k127_5554087_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 467.0
PYH2_k127_5555265_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.833e-321 1002.0
PYH2_k127_5555265_1 Alpha amylase, catalytic domain K01176 - 3.2.1.1 2.48e-273 856.0
PYH2_k127_5555265_10 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000154 269.0
PYH2_k127_5555265_11 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005416 265.0
PYH2_k127_5555265_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000001035 250.0
PYH2_k127_5555265_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000006812 236.0
PYH2_k127_5555265_14 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001365 221.0
PYH2_k127_5555265_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000001294 202.0
PYH2_k127_5555265_16 WHG domain - - - 0.0000000000000000000000000000000000000000000165 169.0
PYH2_k127_5555265_17 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000003698 163.0
PYH2_k127_5555265_18 Domain of unknown function (DUF4062) - - - 0.0000000000000000000000000000000000000007128 164.0
PYH2_k127_5555265_19 RDD family - - - 0.00000000000000000000000000000000000002241 154.0
PYH2_k127_5555265_2 Domain of unknown function (DUF3536) - - - 1.889e-231 742.0
PYH2_k127_5555265_20 positive regulation of translation, ncRNA-mediated K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000000003397 105.0
PYH2_k127_5555265_21 Reeler domain - - - 0.0000000000000000005359 100.0
PYH2_k127_5555265_22 Plasmid stabilization system - - - 0.000000000002762 72.0
PYH2_k127_5555265_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 593.0
PYH2_k127_5555265_4 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 511.0
PYH2_k127_5555265_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 411.0
PYH2_k127_5555265_6 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 315.0
PYH2_k127_5555265_7 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002245 284.0
PYH2_k127_5555265_8 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002594 280.0
PYH2_k127_5555265_9 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 260.0
PYH2_k127_560740_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 503.0
PYH2_k127_560740_1 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 486.0
PYH2_k127_560740_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001105 109.0
PYH2_k127_560740_12 XdhC and CoxI family K07402 - - 0.0000000000000000000001941 102.0
PYH2_k127_560740_13 Protein of unknown function (DUF1232) - - - 0.0000000000000000000001999 102.0
PYH2_k127_560740_14 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000003491 77.0
PYH2_k127_560740_15 Belongs to the universal stress protein A family - - - 0.0000000000002096 81.0
PYH2_k127_560740_16 Putative Ig domain - - - 0.000000000001006 82.0
PYH2_k127_560740_17 guanyl-nucleotide exchange factor activity - - - 0.0001065 57.0
PYH2_k127_560740_18 Belongs to the peptidase M10A family K07999 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022603,GO:0022617,GO:0030163,GO:0030198,GO:0030574,GO:0032501,GO:0032502,GO:0032963,GO:0042475,GO:0042476,GO:0042481,GO:0042487,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044421,GO:0046872,GO:0046914,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051239,GO:0065007,GO:0070011,GO:0070167,GO:0070170,GO:0070173,GO:0071704,GO:0071840,GO:0097186,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:2000026,GO:2000027 - 0.0002561 54.0
PYH2_k127_560740_2 Domain of unknown function (DUF5122) beta-propeller K14274,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 447.0
PYH2_k127_560740_3 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 339.0
PYH2_k127_560740_4 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 310.0
PYH2_k127_560740_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000015 238.0
PYH2_k127_560740_6 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000001686 248.0
PYH2_k127_560740_7 - - - - 0.0000000000000000000000000000000000000000000000000000000009295 211.0
PYH2_k127_560740_8 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000001454 169.0
PYH2_k127_560740_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000001488 129.0
PYH2_k127_5644300_0 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 8.665e-201 635.0
PYH2_k127_5644300_1 FAD linked oxidase domain protein K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 512.0
PYH2_k127_5644300_2 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000001685 238.0
PYH2_k127_5644300_3 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
PYH2_k127_5644300_4 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000000009254 134.0
PYH2_k127_5644300_5 Domain of unknown function (DUF309) K09763 - - 0.000000000000001126 86.0
PYH2_k127_5644300_6 Forkhead associated domain - - - 0.0000000004664 69.0
PYH2_k127_5644300_7 Cysteine synthase B K12339 - 2.5.1.47 0.000006783 49.0
PYH2_k127_5665445_0 PLD-like domain - - - 1.216e-234 739.0
PYH2_k127_5665445_1 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 578.0
PYH2_k127_5665445_10 Domain of unknown function (DUF4129) - - - 0.000000000002673 78.0
PYH2_k127_5665445_11 TIGRFAM TonB K03832 - - 0.0000000002436 74.0
PYH2_k127_5665445_12 Protein of unknown function (DUF2911) - - - 0.0000001659 60.0
PYH2_k127_5665445_13 pathogenesis - - - 0.000000431 62.0
PYH2_k127_5665445_2 PhoPQ-activated pathogenicity-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 495.0
PYH2_k127_5665445_3 unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 345.0
PYH2_k127_5665445_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
PYH2_k127_5665445_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
PYH2_k127_5665445_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000002983 211.0
PYH2_k127_5665445_7 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000005148 180.0
PYH2_k127_5665445_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000001169 137.0
PYH2_k127_5665445_9 - - - - 0.000000000002626 75.0
PYH2_k127_5678967_0 Amidohydrolase family - - - 4.618e-242 760.0
PYH2_k127_5678967_1 - - - - 6.76e-226 716.0
PYH2_k127_5678967_10 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 362.0
PYH2_k127_5678967_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 347.0
PYH2_k127_5678967_12 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 338.0
PYH2_k127_5678967_13 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 320.0
PYH2_k127_5678967_14 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 322.0
PYH2_k127_5678967_15 Methyltransferase domain K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 298.0
PYH2_k127_5678967_16 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007916 267.0
PYH2_k127_5678967_17 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008323 256.0
PYH2_k127_5678967_18 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000002784 222.0
PYH2_k127_5678967_19 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000648 201.0
PYH2_k127_5678967_2 PFAM Amidase - - - 5.851e-197 629.0
PYH2_k127_5678967_20 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000005336 181.0
PYH2_k127_5678967_21 EthD domain - - - 0.00000000000000000000000000000000000002165 147.0
PYH2_k127_5678967_23 - - - - 0.00000000000000000000000000000004575 132.0
PYH2_k127_5678967_24 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000003476 129.0
PYH2_k127_5678967_25 - - - - 0.00000000000000000000001898 112.0
PYH2_k127_5678967_26 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000004948 93.0
PYH2_k127_5678967_27 lactoylglutathione lyase activity - - - 0.00000000000005015 76.0
PYH2_k127_5678967_29 Domain in cystathionine beta-synthase and other proteins. - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.000000000002171 74.0
PYH2_k127_5678967_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 608.0
PYH2_k127_5678967_4 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 534.0
PYH2_k127_5678967_5 PFAM Acetamidase Formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 460.0
PYH2_k127_5678967_6 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 467.0
PYH2_k127_5678967_7 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 397.0
PYH2_k127_5678967_8 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 382.0
PYH2_k127_5678967_9 D-amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 373.0
PYH2_k127_5726403_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 580.0
PYH2_k127_5726403_1 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 401.0
PYH2_k127_5726403_2 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 329.0
PYH2_k127_5726403_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000005503 169.0
PYH2_k127_5726403_4 Class III cytochrome C family - - - 0.0000017 58.0
PYH2_k127_57462_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.14e-216 697.0
PYH2_k127_57462_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 316.0
PYH2_k127_57462_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000009599 117.0
PYH2_k127_57462_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000007597 89.0
PYH2_k127_5749978_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 548.0
PYH2_k127_5749978_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 519.0
PYH2_k127_5749978_10 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000004092 247.0
PYH2_k127_5749978_11 Histidine kinase K02660,K03406,K11525 - - 0.000000000000000000000000000000000000000000000000000000000000000037 252.0
PYH2_k127_5749978_12 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000001805 219.0
PYH2_k127_5749978_13 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000000000000004713 216.0
PYH2_k127_5749978_14 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000005991 216.0
PYH2_k127_5749978_15 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000004641 164.0
PYH2_k127_5749978_16 PhoQ Sensor - - - 0.000000000000000000000000000000000000002334 169.0
PYH2_k127_5749978_17 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000005673 147.0
PYH2_k127_5749978_18 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000009443 126.0
PYH2_k127_5749978_19 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.00000000000000000000000000002035 125.0
PYH2_k127_5749978_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 468.0
PYH2_k127_5749978_20 Response regulator receiver domain K03413 - - 0.0000000000000000000000000001411 119.0
PYH2_k127_5749978_21 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000004621 124.0
PYH2_k127_5749978_22 von Willebrand factor, type A - - - 0.000000000000000000000000456 118.0
PYH2_k127_5749978_23 Chemotaxis protein CheX K03409 - - 0.00000000000000000000002404 106.0
PYH2_k127_5749978_24 lytic transglycosylase activity K03194 - - 0.0000000000000000000003965 110.0
PYH2_k127_5749978_25 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000006058 90.0
PYH2_k127_5749978_26 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.000002246 61.0
PYH2_k127_5749978_27 Domain of unknown function (DUF4388) - - - 0.0000045 59.0
PYH2_k127_5749978_28 Dystroglycan-type cadherin-like domains. - - - 0.00001565 58.0
PYH2_k127_5749978_29 Protein of unknown function DUF86 - - - 0.0003521 45.0
PYH2_k127_5749978_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 449.0
PYH2_k127_5749978_4 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 417.0
PYH2_k127_5749978_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 415.0
PYH2_k127_5749978_6 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 373.0
PYH2_k127_5749978_7 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 364.0
PYH2_k127_5749978_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 299.0
PYH2_k127_5749978_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009255 275.0
PYH2_k127_5780766_0 Heat shock 70 kDa protein K04043 - - 8.571e-235 742.0
PYH2_k127_5780766_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 610.0
PYH2_k127_5780766_10 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002863 274.0
PYH2_k127_5780766_11 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002008 263.0
PYH2_k127_5780766_12 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000003899 192.0
PYH2_k127_5780766_13 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000303 164.0
PYH2_k127_5780766_14 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000002623 134.0
PYH2_k127_5780766_15 iron-sulfur cluster assembly K07400 - - 0.0000000000000000000000000000001536 132.0
PYH2_k127_5780766_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000004035 114.0
PYH2_k127_5780766_17 Putative single-stranded nucleic acids-binding domain K06346 - - 0.0000000000000000000000009235 109.0
PYH2_k127_5780766_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000002549 78.0
PYH2_k127_5780766_19 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000005077 73.0
PYH2_k127_5780766_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 509.0
PYH2_k127_5780766_20 bacterial-type flagellum-dependent cell motility - - - 0.00000000002061 69.0
PYH2_k127_5780766_3 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 505.0
PYH2_k127_5780766_4 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 467.0
PYH2_k127_5780766_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 417.0
PYH2_k127_5780766_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 406.0
PYH2_k127_5780766_7 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 383.0
PYH2_k127_5780766_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 320.0
PYH2_k127_5780766_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 291.0
PYH2_k127_57949_0 HELICc2 K03722 - 3.6.4.12 1.559e-195 630.0
PYH2_k127_57949_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 614.0
PYH2_k127_57949_10 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 410.0
PYH2_k127_57949_11 Trehalose utilisation K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 398.0
PYH2_k127_57949_12 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 379.0
PYH2_k127_57949_13 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 317.0
PYH2_k127_57949_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002181 256.0
PYH2_k127_57949_15 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000006677 257.0
PYH2_k127_57949_16 NAD dependent epimerase/dehydratase family K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001939 246.0
PYH2_k127_57949_17 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001324 246.0
PYH2_k127_57949_18 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000005618 236.0
PYH2_k127_57949_19 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000002116 235.0
PYH2_k127_57949_2 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 548.0
PYH2_k127_57949_20 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000003426 134.0
PYH2_k127_57949_21 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000003861 132.0
PYH2_k127_57949_22 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000003868 133.0
PYH2_k127_57949_23 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000382 133.0
PYH2_k127_57949_24 response to nickel cation - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 - 0.0000000000000000000000116 103.0
PYH2_k127_57949_26 Domain of Unknown Function (DUF350) - - - 0.000000000000001284 81.0
PYH2_k127_57949_27 SdpI/YhfL protein family - - - 0.000000000000008291 83.0
PYH2_k127_57949_29 Di-haem oxidoreductase, putative peroxidase - - - 0.00002848 47.0
PYH2_k127_57949_3 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 521.0
PYH2_k127_57949_30 - - - - 0.00003019 51.0
PYH2_k127_57949_31 - - - - 0.0006926 49.0
PYH2_k127_57949_4 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 490.0
PYH2_k127_57949_5 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 477.0
PYH2_k127_57949_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 449.0
PYH2_k127_57949_7 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 433.0
PYH2_k127_57949_8 Trehalose utilisation K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 426.0
PYH2_k127_57949_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 420.0
PYH2_k127_5825107_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 628.0
PYH2_k127_5825107_1 - K19693 - - 0.0000000000000000000000000000000000000000000000001131 200.0
PYH2_k127_5825107_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000002616 180.0
PYH2_k127_5825107_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000005797 175.0
PYH2_k127_5825107_4 COG3209 Rhs family protein - - - 0.00000000006865 72.0
PYH2_k127_587753_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1770.0
PYH2_k127_587753_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 8.675e-307 951.0
PYH2_k127_587753_10 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 472.0
PYH2_k127_587753_11 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
PYH2_k127_587753_12 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 434.0
PYH2_k127_587753_13 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 347.0
PYH2_k127_587753_14 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 339.0
PYH2_k127_587753_15 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 332.0
PYH2_k127_587753_16 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001043 294.0
PYH2_k127_587753_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
PYH2_k127_587753_18 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000009101 216.0
PYH2_k127_587753_19 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000001676 207.0
PYH2_k127_587753_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.432e-240 762.0
PYH2_k127_587753_20 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000181 201.0
PYH2_k127_587753_21 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000004727 201.0
PYH2_k127_587753_22 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000002132 194.0
PYH2_k127_587753_23 COG1131 ABC-type multidrug transport system, ATPase component K01990,K19340 - - 0.0000000000000000000000000000000000000000000198 173.0
PYH2_k127_587753_24 Cytochrome c - - - 0.0000000000000000000000000000000000000000809 163.0
PYH2_k127_587753_25 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000003887 134.0
PYH2_k127_587753_26 Plasmid stabilization system - - - 0.0000000000000000000000000001726 117.0
PYH2_k127_587753_27 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000002268 114.0
PYH2_k127_587753_28 Helix-turn-helix domain K07726 - - 0.000000000000000000000002078 106.0
PYH2_k127_587753_29 NosL K19342 - - 0.000000000000000000000002096 108.0
PYH2_k127_587753_3 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 9.278e-232 725.0
PYH2_k127_587753_30 Transcriptional regulator - - - 0.00000000000000000001472 96.0
PYH2_k127_587753_31 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000005586 97.0
PYH2_k127_587753_32 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000001796 84.0
PYH2_k127_587753_33 Putative phosphatase (DUF442) - - - 0.00000000000000009237 88.0
PYH2_k127_587753_34 helix_turn_helix, Lux Regulon K07684 - - 0.00000000006526 71.0
PYH2_k127_587753_35 - - - - 0.00003798 54.0
PYH2_k127_587753_4 FtsX-like permease family - - - 1.78e-212 702.0
PYH2_k127_587753_5 COG1012 NAD-dependent aldehyde - - - 3.511e-208 658.0
PYH2_k127_587753_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 577.0
PYH2_k127_587753_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 555.0
PYH2_k127_587753_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 498.0
PYH2_k127_587753_9 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 483.0
PYH2_k127_5898324_0 Glycosyl transferase family 2 - - - 2.515e-195 635.0
PYH2_k127_5898324_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 359.0
PYH2_k127_5898324_2 phage tail tape measure protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009583 269.0
PYH2_k127_5898324_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000007441 198.0
PYH2_k127_5898324_4 Chromosomal replication initiator, DnaA K07491 - - 0.0000000000000000000000000000000000000000000000008492 186.0
PYH2_k127_5898324_5 Sulfatase-modifying factor enzyme 1 K20333 - - 0.00000000000000000000000007197 117.0
PYH2_k127_5898324_6 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000004754 88.0
PYH2_k127_5898324_7 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000003861 56.0
PYH2_k127_5930421_0 Cytochrome c554 and c-prime - - - 4.047e-307 962.0
PYH2_k127_5930421_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.225e-287 905.0
PYH2_k127_5930421_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.538e-260 814.0
PYH2_k127_5930421_3 ASPIC and UnbV - - - 7.759e-259 808.0
PYH2_k127_5930421_4 ASPIC and UnbV - - - 1.234e-239 754.0
PYH2_k127_5930421_5 ASPIC and UnbV - - - 5.641e-218 693.0
PYH2_k127_5930421_6 - - - - 0.00000000000000000000000000001363 119.0
PYH2_k127_5930421_7 - - - - 0.000000000000000000000002838 104.0
PYH2_k127_5930421_8 - - - - 0.00000000000000005857 84.0
PYH2_k127_5930421_9 - - - - 0.000000000000003558 78.0
PYH2_k127_595680_0 Sodium:solute symporter family - - - 4.159e-248 779.0
PYH2_k127_595680_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 574.0
PYH2_k127_595680_10 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 353.0
PYH2_k127_595680_11 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 356.0
PYH2_k127_595680_12 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002797 285.0
PYH2_k127_595680_13 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001629 273.0
PYH2_k127_595680_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008372 266.0
PYH2_k127_595680_15 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001942 252.0
PYH2_k127_595680_16 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000002478 183.0
PYH2_k127_595680_17 FAD binding domain - - - 0.0000000000000000000000000000000000000000002447 174.0
PYH2_k127_595680_18 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000893 162.0
PYH2_k127_595680_19 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000001433 159.0
PYH2_k127_595680_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 547.0
PYH2_k127_595680_20 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000000000000000002137 144.0
PYH2_k127_595680_21 Methyltransferase domain - - - 0.0000000000000000000000000000000001069 147.0
PYH2_k127_595680_22 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000003627 138.0
PYH2_k127_595680_23 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000003887 134.0
PYH2_k127_595680_24 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000003493 118.0
PYH2_k127_595680_25 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000001629 124.0
PYH2_k127_595680_26 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000001099 101.0
PYH2_k127_595680_27 NAD+ binding K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.00000000000000000000538 94.0
PYH2_k127_595680_28 lipolytic protein G-D-S-L family - - - 0.0000000000000001314 82.0
PYH2_k127_595680_29 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000003445 90.0
PYH2_k127_595680_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 519.0
PYH2_k127_595680_31 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000001796 62.0
PYH2_k127_595680_4 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 460.0
PYH2_k127_595680_5 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 445.0
PYH2_k127_595680_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 436.0
PYH2_k127_595680_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 416.0
PYH2_k127_595680_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 391.0
PYH2_k127_595680_9 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 390.0
PYH2_k127_6006363_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.395e-222 698.0
PYH2_k127_6006363_1 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 364.0
PYH2_k127_6006363_2 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000000000000000009743 164.0
PYH2_k127_6006363_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000001163 64.0
PYH2_k127_602033_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.318e-314 983.0
PYH2_k127_602033_1 Elongation factor G, domain IV K02355 - - 1.037e-248 788.0
PYH2_k127_602033_10 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000003655 197.0
PYH2_k127_602033_11 - - - - 0.00000000000000000000000000000000000000000000000000002876 195.0
PYH2_k127_602033_12 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000003771 185.0
PYH2_k127_602033_13 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000004212 159.0
PYH2_k127_602033_14 PFAM NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000004575 140.0
PYH2_k127_602033_15 HEPN domain - - - 0.00000000000000000000000000000001312 135.0
PYH2_k127_602033_16 Protein of unknown function (DUF2847) - - - 0.00000000000000000002448 96.0
PYH2_k127_602033_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000009725 97.0
PYH2_k127_602033_18 CAAX protease self-immunity K07052 - - 0.000000004963 68.0
PYH2_k127_602033_2 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 553.0
PYH2_k127_602033_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 364.0
PYH2_k127_602033_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 364.0
PYH2_k127_602033_5 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 319.0
PYH2_k127_602033_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 305.0
PYH2_k127_602033_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003646 283.0
PYH2_k127_602033_8 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000008037 239.0
PYH2_k127_602033_9 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001796 204.0
PYH2_k127_6028737_0 TonB-dependent receptor - - - 3.064e-251 811.0
PYH2_k127_6028737_1 TonB-dependent receptor - - - 6.156e-218 717.0
PYH2_k127_6028737_2 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002008 255.0
PYH2_k127_6028737_3 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000009235 224.0
PYH2_k127_6086315_0 GAF domain - - - 1.244e-252 823.0
PYH2_k127_6086315_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.752e-198 640.0
PYH2_k127_6086315_10 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 364.0
PYH2_k127_6086315_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 311.0
PYH2_k127_6086315_12 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002229 245.0
PYH2_k127_6086315_13 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 228.0
PYH2_k127_6086315_14 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000000000002969 178.0
PYH2_k127_6086315_15 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000000002659 192.0
PYH2_k127_6086315_16 DNA mismatch endonuclease Vsr K07458 - - 0.000000000000000000000000000000000000000000001985 172.0
PYH2_k127_6086315_17 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000006706 144.0
PYH2_k127_6086315_18 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000001504 149.0
PYH2_k127_6086315_19 guanyl-nucleotide exchange factor activity K06978,K12287,K21105 - 3.1.1.102 0.00000000000000000000000000000000003977 157.0
PYH2_k127_6086315_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 519.0
PYH2_k127_6086315_20 Extracellular nuclease K07004 - - 0.0000000000000000000000000000000008257 153.0
PYH2_k127_6086315_21 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000004282 121.0
PYH2_k127_6086315_22 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000002076 108.0
PYH2_k127_6086315_24 - - - - 0.00000000000003141 80.0
PYH2_k127_6086315_25 abc transporter (atp-binding protein) K06147 - - 0.00000001109 63.0
PYH2_k127_6086315_3 DNA (cytosine-5-)-methyltransferase activity K00558 - 2.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 486.0
PYH2_k127_6086315_4 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 503.0
PYH2_k127_6086315_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 467.0
PYH2_k127_6086315_6 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 467.0
PYH2_k127_6086315_7 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 421.0
PYH2_k127_6086315_8 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 419.0
PYH2_k127_6086315_9 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 394.0
PYH2_k127_6130029_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 522.0
PYH2_k127_6130029_1 cellulose binding K13735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 518.0
PYH2_k127_6130029_2 repeat protein - - - 0.0000000000000000000000000000000008399 152.0
PYH2_k127_6130029_3 repeat protein - - - 0.0001754 45.0
PYH2_k127_622348_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 9.57e-309 960.0
PYH2_k127_622348_1 Peptidase family M49 - - - 1.228e-199 636.0
PYH2_k127_622348_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 358.0
PYH2_k127_622348_3 SMART RNP-1 like RNA-binding protein - - - 0.0000000000000000000007445 97.0
PYH2_k127_622348_4 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000005352 53.0
PYH2_k127_6228372_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1214.0
PYH2_k127_6228372_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 585.0
PYH2_k127_6228372_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 514.0
PYH2_k127_6228372_3 Sporulation initiation inhibitor K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.00000000002268 68.0
PYH2_k127_6228372_4 PFAM Resolvase domain - - - 0.00000001254 58.0
PYH2_k127_6228372_5 Resolvase, N terminal domain - - - 0.000004003 50.0
PYH2_k127_629918_0 Multicopper oxidase - - - 0.0 1835.0
PYH2_k127_629918_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.224e-271 865.0
PYH2_k127_629918_10 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 350.0
PYH2_k127_629918_11 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 339.0
PYH2_k127_629918_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 320.0
PYH2_k127_629918_13 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 301.0
PYH2_k127_629918_14 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 306.0
PYH2_k127_629918_15 Glycosyltransferase like family K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003752 286.0
PYH2_k127_629918_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003807 278.0
PYH2_k127_629918_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005074 275.0
PYH2_k127_629918_18 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000001266 238.0
PYH2_k127_629918_19 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000004803 231.0
PYH2_k127_629918_2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 4.994e-202 644.0
PYH2_k127_629918_20 InterPro IPR008538 - - - 0.0000000000000000000000000000000000000000000000000000000001649 208.0
PYH2_k127_629918_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000003016 226.0
PYH2_k127_629918_22 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000000000000000000000009603 209.0
PYH2_k127_629918_23 COG0515 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000001207 207.0
PYH2_k127_629918_24 PAS fold - - - 0.00000000000000000000000000000000000000000000000000003706 207.0
PYH2_k127_629918_25 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000005623 192.0
PYH2_k127_629918_26 Cupredoxin-like domain - - - 0.000000000000000000000000000000000000000001158 160.0
PYH2_k127_629918_27 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000001009 157.0
PYH2_k127_629918_28 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000001358 132.0
PYH2_k127_629918_29 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000002561 116.0
PYH2_k127_629918_3 amine dehydrogenase activity - - - 4.392e-198 640.0
PYH2_k127_629918_30 response regulator K07714 - - 0.000000000000000000001012 99.0
PYH2_k127_629918_31 Uncharacterized conserved protein (DUF2304) - - - 0.0000000000009653 72.0
PYH2_k127_629918_33 Multicopper oxidase - - - 0.0001194 53.0
PYH2_k127_629918_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 554.0
PYH2_k127_629918_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 533.0
PYH2_k127_629918_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 400.0
PYH2_k127_629918_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 394.0
PYH2_k127_629918_8 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 388.0
PYH2_k127_629918_9 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
PYH2_k127_6421614_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.601e-280 871.0
PYH2_k127_6421614_1 Tetratricopeptide repeats K12132 - 2.7.11.1 1.247e-212 685.0
PYH2_k127_6421614_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000004611 203.0
PYH2_k127_6421614_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000003464 175.0
PYH2_k127_6421614_12 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000001481 179.0
PYH2_k127_6421614_13 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000002253 123.0
PYH2_k127_6421614_14 SNARE associated Golgi protein - - - 0.00000000000000000000002402 108.0
PYH2_k127_6421614_15 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000002349 104.0
PYH2_k127_6421614_16 Subtilase family - - - 0.00000000000000000003194 100.0
PYH2_k127_6421614_17 Protein of unknown function (DUF2442) - - - 0.00000000000000000006276 92.0
PYH2_k127_6421614_18 energy transducer activity K03832 - - 0.000000000000000009691 93.0
PYH2_k127_6421614_19 nitrilase K01501,K01502 - 3.5.5.1,3.5.5.7 0.000000000001977 67.0
PYH2_k127_6421614_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 596.0
PYH2_k127_6421614_20 COGs COG4636 conserved - - - 0.0000002875 54.0
PYH2_k127_6421614_22 Addiction module component, TIGR02574 family - - - 0.00002064 51.0
PYH2_k127_6421614_23 domain protein - - - 0.00003245 54.0
PYH2_k127_6421614_24 protein trimerization - - - 0.00009502 54.0
PYH2_k127_6421614_25 Tetratricopeptide repeat - - - 0.0001301 54.0
PYH2_k127_6421614_26 Parallel beta-helix repeats - - - 0.0003605 50.0
PYH2_k127_6421614_27 - - - - 0.000404 47.0
PYH2_k127_6421614_28 anti-sigma factor - GO:0005575,GO:0016020 - 0.0009448 50.0
PYH2_k127_6421614_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 363.0
PYH2_k127_6421614_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
PYH2_k127_6421614_5 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 325.0
PYH2_k127_6421614_6 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001818 263.0
PYH2_k127_6421614_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000668 263.0
PYH2_k127_6421614_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007336 253.0
PYH2_k127_6421614_9 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000009542 239.0
PYH2_k127_6425169_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 3.528e-210 657.0
PYH2_k127_6425169_1 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 563.0
PYH2_k127_6425169_10 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002464 239.0
PYH2_k127_6425169_11 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001297 232.0
PYH2_k127_6425169_12 cytolysis by virus of host cell K01185 - 3.2.1.17 0.000000000000000000000000000000000000000000002064 169.0
PYH2_k127_6425169_13 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000305 149.0
PYH2_k127_6425169_14 COGs COG1487 nucleic acid-binding protein contains PIN domain K18828 - - 0.00000000000000000000000002959 116.0
PYH2_k127_6425169_15 Transposase IS200 like K07491 - - 0.00001257 56.0
PYH2_k127_6425169_16 Gaf domain K03832 - - 0.00009057 54.0
PYH2_k127_6425169_17 Peptidase S9, prolyl oligopeptidase, catalytic domain K01354 - 3.4.21.83 0.0003641 43.0
PYH2_k127_6425169_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 510.0
PYH2_k127_6425169_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 475.0
PYH2_k127_6425169_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 384.0
PYH2_k127_6425169_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 377.0
PYH2_k127_6425169_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 365.0
PYH2_k127_6425169_7 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 364.0
PYH2_k127_6425169_8 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 327.0
PYH2_k127_6425169_9 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 321.0
PYH2_k127_6524158_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.01e-211 665.0
PYH2_k127_6524158_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 481.0
PYH2_k127_6524158_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619,K01840 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000009419 273.0
PYH2_k127_6524158_11 Mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000007006 159.0
PYH2_k127_6524158_12 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000006098 146.0
PYH2_k127_6524158_13 TIGRFAM TonB K03832 - - 0.0000000000000000000000002335 118.0
PYH2_k127_6524158_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000004243 110.0
PYH2_k127_6524158_15 Roadblock/LC7 domain - - - 0.0000005297 56.0
PYH2_k127_6524158_16 Periplasmic protein TonB links inner and outer membranes - - - 0.0001952 53.0
PYH2_k127_6524158_2 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 465.0
PYH2_k127_6524158_3 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 439.0
PYH2_k127_6524158_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 429.0
PYH2_k127_6524158_5 Phosphate acetyl/butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 343.0
PYH2_k127_6524158_6 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 307.0
PYH2_k127_6524158_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003277 280.0
PYH2_k127_6524158_8 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003295 279.0
PYH2_k127_6524158_9 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 273.0
PYH2_k127_6626999_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 454.0
PYH2_k127_6626999_1 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 342.0
PYH2_k127_6626999_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008793 286.0
PYH2_k127_6626999_3 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007083 265.0
PYH2_k127_6684894_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 300.0
PYH2_k127_6684894_1 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000001011 197.0
PYH2_k127_6684894_2 ABC-type multidrug transport system ATPase component - - - 0.00000000002574 78.0
PYH2_k127_6719639_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001754 300.0
PYH2_k127_6719639_1 - - - - 0.000000000000000000000000000000000000000003463 166.0
PYH2_k127_6719639_2 Metallo-peptidase family M12 - - - 0.00000000000000000000000000007132 136.0
PYH2_k127_6768018_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 497.0
PYH2_k127_6768018_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 385.0
PYH2_k127_6768018_2 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 330.0
PYH2_k127_6768018_3 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
PYH2_k127_6768018_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 302.0
PYH2_k127_6768018_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 323.0
PYH2_k127_6768018_6 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 280.0
PYH2_k127_6768018_7 - - - - 0.00000000000000000000000000000000000005888 147.0
PYH2_k127_6768018_8 - - - - 0.000000000004342 71.0
PYH2_k127_6838391_0 ABC transporter K15738 - - 1.622e-206 660.0
PYH2_k127_6838391_1 A-macroglobulin complement component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 646.0
PYH2_k127_6838391_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
PYH2_k127_6838391_3 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000009372 180.0
PYH2_k127_6838391_4 - - - - 0.0000000000000000000000000000000002355 132.0
PYH2_k127_6838391_5 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000002991 95.0
PYH2_k127_6838391_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000003987 88.0
PYH2_k127_6838391_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000004622 69.0
PYH2_k127_6842217_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 387.0
PYH2_k127_6842217_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 340.0
PYH2_k127_6842217_10 - - - - 0.000000000003464 70.0
PYH2_k127_6842217_11 - - - - 0.000000001233 68.0
PYH2_k127_6842217_12 - - - - 0.000000002296 62.0
PYH2_k127_6842217_2 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
PYH2_k127_6842217_3 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005464 276.0
PYH2_k127_6842217_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005025 224.0
PYH2_k127_6842217_5 SnoaL-like domain - - - 0.00000000000000000000000000000000001354 141.0
PYH2_k127_6842217_6 DinB superfamily - - - 0.00000000000000000000000000000002093 132.0
PYH2_k127_6842217_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000032 115.0
PYH2_k127_6842217_8 methyltransferase - - - 0.00000000000000000000000008007 108.0
PYH2_k127_6842217_9 - - - - 0.00000000000000000000002393 102.0
PYH2_k127_6943495_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.133e-316 990.0
PYH2_k127_6943495_1 Flavoprotein involved in K transport - - - 2.986e-196 623.0
PYH2_k127_6943495_10 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 300.0
PYH2_k127_6943495_11 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000002994 273.0
PYH2_k127_6943495_12 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005369 259.0
PYH2_k127_6943495_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
PYH2_k127_6943495_14 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000004968 220.0
PYH2_k127_6943495_15 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000005418 189.0
PYH2_k127_6943495_16 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000115 166.0
PYH2_k127_6943495_17 COGs COG4636 conserved - - - 0.0000000000000000000000000000000000000000004575 164.0
PYH2_k127_6943495_18 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000004694 150.0
PYH2_k127_6943495_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000001084 155.0
PYH2_k127_6943495_2 enterobactin catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 604.0
PYH2_k127_6943495_20 diguanylate cyclase - - - 0.000000000000000000000000000000000005345 149.0
PYH2_k127_6943495_21 cheY-homologous receiver domain - - - 0.000000000000000000000000000000001692 149.0
PYH2_k127_6943495_22 metal-dependent membrane protease - - - 0.000000000000000000000000000000006092 140.0
PYH2_k127_6943495_23 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000004219 105.0
PYH2_k127_6943495_24 Putative NAD(P)-binding K03499 - - 0.0000000000000000000004438 109.0
PYH2_k127_6943495_25 RESPONSE REGULATOR receiver - - - 0.000000000000000000002044 98.0
PYH2_k127_6943495_26 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000009741 109.0
PYH2_k127_6943495_27 - - - - 0.0000000000000000203 88.0
PYH2_k127_6943495_28 SnoaL-like domain - - - 0.0000000000001226 74.0
PYH2_k127_6943495_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 557.0
PYH2_k127_6943495_30 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000001351 68.0
PYH2_k127_6943495_31 SnoaL-like domain - - - 0.000005633 53.0
PYH2_k127_6943495_32 Helix-turn-helix domain - - - 0.00002493 50.0
PYH2_k127_6943495_33 CHASE4 domain - - - 0.000125 50.0
PYH2_k127_6943495_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0004985 53.0
PYH2_k127_6943495_4 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 538.0
PYH2_k127_6943495_5 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 515.0
PYH2_k127_6943495_6 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 490.0
PYH2_k127_6943495_7 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 489.0
PYH2_k127_6943495_8 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 423.0
PYH2_k127_6943495_9 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 409.0
PYH2_k127_6967024_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0 1402.0
PYH2_k127_6967024_1 ribosome binding - - - 1.306e-251 807.0
PYH2_k127_6967024_2 - - - - 1.622e-198 637.0
PYH2_k127_6968372_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.514e-253 791.0
PYH2_k127_6968372_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 539.0
PYH2_k127_6968372_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000002866 254.0
PYH2_k127_6968372_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000001157 236.0
PYH2_k127_6968372_4 Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic-like K20416 - 1.14.19.42 0.00000000000000000000000000000000000000000124 168.0
PYH2_k127_6968372_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000006288 111.0
PYH2_k127_6981303_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 6.968e-303 951.0
PYH2_k127_6981303_1 Prolyl oligopeptidase family - - - 5.706e-278 874.0
PYH2_k127_6981303_10 Peptidase dimerisation domain K13049 - - 0.000000000000000005297 83.0
PYH2_k127_6981303_2 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 587.0
PYH2_k127_6981303_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 522.0
PYH2_k127_6981303_4 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 493.0
PYH2_k127_6981303_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 441.0
PYH2_k127_6981303_6 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000001447 233.0
PYH2_k127_6981303_7 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000004608 197.0
PYH2_k127_6981303_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000001557 119.0
PYH2_k127_6981303_9 - - - - 0.0000000000000000000000071 106.0
PYH2_k127_7006410_0 cellulose binding - - - 1.215e-249 801.0
PYH2_k127_7006410_1 Subtilase family - - - 2.687e-225 715.0
PYH2_k127_7006410_10 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 438.0
PYH2_k127_7006410_11 threonine synthase activity K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 421.0
PYH2_k127_7006410_12 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 407.0
PYH2_k127_7006410_13 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 377.0
PYH2_k127_7006410_14 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 377.0
PYH2_k127_7006410_15 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 360.0
PYH2_k127_7006410_16 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 348.0
PYH2_k127_7006410_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003813 275.0
PYH2_k127_7006410_18 tRNA m6t6A37 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001565 232.0
PYH2_k127_7006410_19 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000176 238.0
PYH2_k127_7006410_2 Amidohydrolase family K06015 - 3.5.1.81 2.814e-224 708.0
PYH2_k127_7006410_20 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001782 255.0
PYH2_k127_7006410_21 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001993 225.0
PYH2_k127_7006410_22 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000007667 206.0
PYH2_k127_7006410_23 - - - - 0.0000000000000000000000000000000000000000000000000000003481 206.0
PYH2_k127_7006410_24 - - - - 0.00000000000000000000000000000000000000000000000224 186.0
PYH2_k127_7006410_25 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000311 155.0
PYH2_k127_7006410_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000001076 138.0
PYH2_k127_7006410_27 - - - - 0.000000000000000000000000000005435 124.0
PYH2_k127_7006410_28 - - - - 0.000000000000000000002766 96.0
PYH2_k127_7006410_29 Protein of unknown function (DUF983) - - - 0.000000000000000001117 90.0
PYH2_k127_7006410_3 PFAM TonB-dependent Receptor Plug K02014,K16089 - - 1.655e-219 702.0
PYH2_k127_7006410_30 Transposase IS200 like - - - 0.000000000008126 69.0
PYH2_k127_7006410_31 Domain of unknown function (DUF4956) - - - 0.00000003602 65.0
PYH2_k127_7006410_32 - - - - 0.000009353 48.0
PYH2_k127_7006410_4 MacB-like periplasmic core domain - - - 4.874e-197 642.0
PYH2_k127_7006410_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 613.0
PYH2_k127_7006410_6 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 580.0
PYH2_k127_7006410_7 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 518.0
PYH2_k127_7006410_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 524.0
PYH2_k127_7006410_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 469.0
PYH2_k127_7024205_0 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 2.919e-213 672.0
PYH2_k127_7024205_1 serine-type peptidase activity K01278 - 3.4.14.5 4.654e-210 675.0
PYH2_k127_7024205_10 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.0000000000000000000000000000000002521 151.0
PYH2_k127_7024205_11 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.000000000000000000000000000004001 138.0
PYH2_k127_7024205_12 - - - - 0.0000000000000000000001689 112.0
PYH2_k127_7024205_13 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000001986 83.0
PYH2_k127_7024205_14 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000814 75.0
PYH2_k127_7024205_15 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.0000008402 62.0
PYH2_k127_7024205_16 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000006437 49.0
PYH2_k127_7024205_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 535.0
PYH2_k127_7024205_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 509.0
PYH2_k127_7024205_4 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 394.0
PYH2_k127_7024205_5 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 370.0
PYH2_k127_7024205_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 319.0
PYH2_k127_7024205_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001712 291.0
PYH2_k127_7024205_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH2_k127_7024205_9 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000002076 210.0
PYH2_k127_7024211_0 helicase activity - - - 0.0 1042.0
PYH2_k127_7024211_1 Urocanase Rossmann-like domain K01712 - 4.2.1.49 2.336e-276 859.0
PYH2_k127_7024211_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 523.0
PYH2_k127_7024211_101 Peptidoglycan-binding - - - 0.0007931 52.0
PYH2_k127_7024211_11 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 522.0
PYH2_k127_7024211_12 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 491.0
PYH2_k127_7024211_13 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 482.0
PYH2_k127_7024211_14 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 476.0
PYH2_k127_7024211_15 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 473.0
PYH2_k127_7024211_16 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 475.0
PYH2_k127_7024211_17 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 444.0
PYH2_k127_7024211_18 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 434.0
PYH2_k127_7024211_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 426.0
PYH2_k127_7024211_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.628e-250 786.0
PYH2_k127_7024211_20 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 415.0
PYH2_k127_7024211_21 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
PYH2_k127_7024211_22 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 400.0
PYH2_k127_7024211_23 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 384.0
PYH2_k127_7024211_24 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 398.0
PYH2_k127_7024211_25 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 381.0
PYH2_k127_7024211_26 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 368.0
PYH2_k127_7024211_27 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 368.0
PYH2_k127_7024211_28 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 379.0
PYH2_k127_7024211_29 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 368.0
PYH2_k127_7024211_3 Dienelactone hydrolase family - - - 5.629e-247 782.0
PYH2_k127_7024211_30 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 358.0
PYH2_k127_7024211_31 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 328.0
PYH2_k127_7024211_32 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 332.0
PYH2_k127_7024211_33 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 328.0
PYH2_k127_7024211_34 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 340.0
PYH2_k127_7024211_35 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 338.0
PYH2_k127_7024211_36 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 308.0
PYH2_k127_7024211_37 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 304.0
PYH2_k127_7024211_38 integrase domain protein SAM domain protein K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 301.0
PYH2_k127_7024211_39 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 298.0
PYH2_k127_7024211_4 aminopeptidase - - - 5.925e-210 667.0
PYH2_k127_7024211_40 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 295.0
PYH2_k127_7024211_41 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 309.0
PYH2_k127_7024211_42 transferase hexapeptide K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000127 282.0
PYH2_k127_7024211_43 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000005468 261.0
PYH2_k127_7024211_44 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
PYH2_k127_7024211_45 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000001558 238.0
PYH2_k127_7024211_46 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000001448 231.0
PYH2_k127_7024211_47 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000005639 235.0
PYH2_k127_7024211_48 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000001054 229.0
PYH2_k127_7024211_49 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000000000000000002412 234.0
PYH2_k127_7024211_5 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 587.0
PYH2_k127_7024211_50 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000348 238.0
PYH2_k127_7024211_51 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000001561 222.0
PYH2_k127_7024211_52 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000008379 223.0
PYH2_k127_7024211_53 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000002782 209.0
PYH2_k127_7024211_54 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000275 210.0
PYH2_k127_7024211_55 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000002739 198.0
PYH2_k127_7024211_56 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000002772 206.0
PYH2_k127_7024211_57 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000001998 214.0
PYH2_k127_7024211_58 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000005503 205.0
PYH2_k127_7024211_59 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000002122 183.0
PYH2_k127_7024211_6 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 574.0
PYH2_k127_7024211_60 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000000000000000000000000000000000000000000000002829 200.0
PYH2_k127_7024211_61 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000005587 190.0
PYH2_k127_7024211_62 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000003175 179.0
PYH2_k127_7024211_63 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000003379 182.0
PYH2_k127_7024211_64 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000109 177.0
PYH2_k127_7024211_65 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000005329 176.0
PYH2_k127_7024211_66 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000004623 169.0
PYH2_k127_7024211_67 Helix-turn-helix K21498 - - 0.00000000000000000000000000000000000000000008101 161.0
PYH2_k127_7024211_68 Belongs to the ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000003944 156.0
PYH2_k127_7024211_69 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000007328 144.0
PYH2_k127_7024211_7 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 572.0
PYH2_k127_7024211_70 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000001297 147.0
PYH2_k127_7024211_71 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000000003704 134.0
PYH2_k127_7024211_72 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000009577 145.0
PYH2_k127_7024211_73 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000008132 120.0
PYH2_k127_7024211_74 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000001493 120.0
PYH2_k127_7024211_75 RNA-binding protein - - - 0.000000000000000000000000000323 117.0
PYH2_k127_7024211_76 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000009307 115.0
PYH2_k127_7024211_77 cellulose binding - - - 0.00000000000000000000000001599 123.0
PYH2_k127_7024211_78 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000001647 116.0
PYH2_k127_7024211_79 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000005171 111.0
PYH2_k127_7024211_8 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 539.0
PYH2_k127_7024211_80 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000001535 94.0
PYH2_k127_7024211_81 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000192 100.0
PYH2_k127_7024211_82 DoxX K15977 - - 0.00000000000000000004491 96.0
PYH2_k127_7024211_83 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000002732 103.0
PYH2_k127_7024211_84 multi-organism process - - - 0.00000000000000009846 94.0
PYH2_k127_7024211_85 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000264 85.0
PYH2_k127_7024211_86 Tetratricopeptide repeat - - - 0.000000000000001932 86.0
PYH2_k127_7024211_87 Gcn5-related n-acetyltransferase K06976 - - 0.00000000000002756 85.0
PYH2_k127_7024211_88 - - - - 0.0000000000001964 74.0
PYH2_k127_7024211_89 Zn-ribbon protein possibly nucleic acid-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000006518 79.0
PYH2_k127_7024211_9 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 544.0
PYH2_k127_7024211_90 integral membrane protein - - - 0.000000000001565 78.0
PYH2_k127_7024211_91 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000219 77.0
PYH2_k127_7024211_92 MucB/RseB N-terminal domain - - - 0.000000000004623 77.0
PYH2_k127_7024211_93 NUDIX domain - - - 0.00000000003407 70.0
PYH2_k127_7024211_94 Glutaredoxin K03676 - - 0.0000000003685 64.0
PYH2_k127_7024211_95 Forkhead associated domain K03466 - - 0.0000000003823 70.0
PYH2_k127_7024211_96 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.0000001273 55.0
PYH2_k127_7024211_97 PFAM von Willebrand factor type A - - - 0.0000004254 62.0
PYH2_k127_7024211_98 Zinc carboxypeptidase - - - 0.00001109 55.0
PYH2_k127_7024211_99 energy transducer activity K03646,K03832 - - 0.00001716 56.0
PYH2_k127_713269_0 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
PYH2_k127_713269_1 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003339 279.0
PYH2_k127_713269_10 Neuraminidase (sialidase) - - - 0.0000000000000000003599 89.0
PYH2_k127_713269_11 - - - - 0.000000000000000002048 91.0
PYH2_k127_713269_12 response regulator receiver - - - 0.00000000000306 72.0
PYH2_k127_713269_13 Putative peptidoglycan binding domain - - - 0.000000000003631 79.0
PYH2_k127_713269_15 bacterial OsmY and nodulation domain - - - 0.00000000001053 73.0
PYH2_k127_713269_17 ErfK YbiS YcfS YnhG - - - 0.000000001006 71.0
PYH2_k127_713269_2 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000007191 224.0
PYH2_k127_713269_3 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000000000000008867 208.0
PYH2_k127_713269_4 - - - - 0.00000000000000000000000000000000000000000000000000001276 194.0
PYH2_k127_713269_5 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000000000000000000000000000000000005425 196.0
PYH2_k127_713269_6 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000003258 167.0
PYH2_k127_713269_8 Transglycosylase associated protein - - - 0.0000000000000000000000007718 106.0
PYH2_k127_713269_9 - - - - 0.00000000000000000000004112 102.0
PYH2_k127_71541_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.017e-202 660.0
PYH2_k127_71541_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 465.0
PYH2_k127_71541_10 response regulator K07685 - - 0.0000000000000000000000000000000000000000000000006354 183.0
PYH2_k127_71541_11 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000000002936 126.0
PYH2_k127_71541_12 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000001425 117.0
PYH2_k127_71541_13 copper resistance K07233,K07798,K14588 - - 0.000000000000000000000001353 115.0
PYH2_k127_71541_14 Protein of unknown function (DUF2911) - - - 0.000000000000001871 87.0
PYH2_k127_71541_15 Tfp pilus assembly protein FimV - - - 0.000000000006365 77.0
PYH2_k127_71541_16 Winged helix DNA-binding domain - - - 0.00000001231 59.0
PYH2_k127_71541_17 TonB-dependent Receptor Plug Domain - - - 0.00000006159 60.0
PYH2_k127_71541_18 Protein of unknown function (DUF1573) - - - 0.0000003441 56.0
PYH2_k127_71541_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 416.0
PYH2_k127_71541_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 372.0
PYH2_k127_71541_4 peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 325.0
PYH2_k127_71541_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000001007 203.0
PYH2_k127_71541_6 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000000001705 203.0
PYH2_k127_71541_7 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000007584 200.0
PYH2_k127_71541_8 PFAM TonB-dependent Receptor - - - 0.0000000000000000000000000000000000000000000000000001832 203.0
PYH2_k127_71541_9 PFAM TonB-dependent Receptor - - - 0.000000000000000000000000000000000000000000000000002309 207.0
PYH2_k127_728856_0 TIGRFAM glutamine synthetase, type I K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 595.0
PYH2_k127_728856_1 sequence-specific DNA binding K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 427.0
PYH2_k127_728856_11 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000002538 74.0
PYH2_k127_728856_12 Caspase domain - - - 0.00000001316 67.0
PYH2_k127_728856_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 406.0
PYH2_k127_728856_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 334.0
PYH2_k127_728856_4 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 245.0
PYH2_k127_728856_5 Subtilase family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000186 251.0
PYH2_k127_728856_6 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000003821 187.0
PYH2_k127_728856_7 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000007296 181.0
PYH2_k127_728856_8 AAA domain - - - 0.000000000000000000000000000000002124 136.0
PYH2_k127_728856_9 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000009607 136.0
PYH2_k127_7330243_0 4Fe-4S dicluster domain K00184 - - 0.0 1152.0
PYH2_k127_7330243_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.747e-305 957.0
PYH2_k127_7330243_10 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 399.0
PYH2_k127_7330243_11 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 372.0
PYH2_k127_7330243_12 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
PYH2_k127_7330243_13 Phytase K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 326.0
PYH2_k127_7330243_14 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 303.0
PYH2_k127_7330243_15 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 302.0
PYH2_k127_7330243_16 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 295.0
PYH2_k127_7330243_17 Acetamidase formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
PYH2_k127_7330243_18 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001232 243.0
PYH2_k127_7330243_19 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
PYH2_k127_7330243_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.806e-276 857.0
PYH2_k127_7330243_20 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
PYH2_k127_7330243_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000003071 226.0
PYH2_k127_7330243_22 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000004149 236.0
PYH2_k127_7330243_23 - - - - 0.00000000000000000000000000000000000000000000000006479 193.0
PYH2_k127_7330243_24 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000002204 174.0
PYH2_k127_7330243_25 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000001981 154.0
PYH2_k127_7330243_26 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000004248 156.0
PYH2_k127_7330243_27 von Willebrand factor, type A - - - 0.00000000000000000000000000000002373 146.0
PYH2_k127_7330243_28 Putative restriction endonuclease - - - 0.00000000000000000000000000000009049 126.0
PYH2_k127_7330243_29 von Willebrand factor, type A - - - 0.0000000000000000000000000003208 132.0
PYH2_k127_7330243_3 GTP-binding protein TypA K06207 - - 6.361e-266 831.0
PYH2_k127_7330243_30 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000007244 111.0
PYH2_k127_7330243_31 amine dehydrogenase activity - - - 0.00000000000000000000000002174 121.0
PYH2_k127_7330243_32 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000001961 103.0
PYH2_k127_7330243_33 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000005427 98.0
PYH2_k127_7330243_34 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000007466 102.0
PYH2_k127_7330243_35 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000008993 100.0
PYH2_k127_7330243_36 Transposase IS200 like - - - 0.0000000000000003363 80.0
PYH2_k127_7330243_37 - - - - 0.000000000000000805 80.0
PYH2_k127_7330243_38 - - - - 0.000000000000002454 83.0
PYH2_k127_7330243_39 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000007884 68.0
PYH2_k127_7330243_4 Polysulphide reductase, NrfD K00185 - - 2.019e-213 670.0
PYH2_k127_7330243_40 DinB superfamily K07552 - - 0.000002566 51.0
PYH2_k127_7330243_5 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 604.0
PYH2_k127_7330243_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 511.0
PYH2_k127_7330243_7 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 479.0
PYH2_k127_7330243_8 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 428.0
PYH2_k127_7330243_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 392.0
PYH2_k127_7415281_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 501.0
PYH2_k127_7415281_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 433.0
PYH2_k127_7415281_10 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000005546 139.0
PYH2_k127_7415281_11 HYR domain - - - 0.00000000000000000000000000001277 138.0
PYH2_k127_7415281_12 - - - - 0.00000000000000000000000000001431 139.0
PYH2_k127_7415281_13 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000422 119.0
PYH2_k127_7415281_14 metallopeptidase activity K08738,K20276 - - 0.00000000000000003067 97.0
PYH2_k127_7415281_15 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000401 81.0
PYH2_k127_7415281_17 COG1943 Transposase and inactivated derivatives - - - 0.00000001167 64.0
PYH2_k127_7415281_18 Evidence 5 No homology to any previously reported sequences - - - 0.0000006485 63.0
PYH2_k127_7415281_19 self proteolysis - - - 0.00002377 55.0
PYH2_k127_7415281_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 453.0
PYH2_k127_7415281_20 von Willebrand factor (vWF) type A domain - - - 0.00005855 57.0
PYH2_k127_7415281_3 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 439.0
PYH2_k127_7415281_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 289.0
PYH2_k127_7415281_5 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000007854 181.0
PYH2_k127_7415281_6 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000008062 184.0
PYH2_k127_7415281_7 - - - - 0.000000000000000000000000000000000000000000001426 171.0
PYH2_k127_7415281_8 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.0000000000000000000000000000000000000001377 173.0
PYH2_k127_7415281_9 Subtilase family K01179,K13276 GO:0005575,GO:0005576 3.2.1.4 0.0000000000000000000000000000002598 143.0
PYH2_k127_7470351_0 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 437.0
PYH2_k127_7470351_1 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 372.0
PYH2_k127_7470351_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406,K21009 - - 0.0000000000000000000000000000000000000000001625 160.0
PYH2_k127_7470351_3 PAS domain - - - 0.0000000000000000000004288 96.0
PYH2_k127_7477256_0 Patatin-like phospholipase - - - 5.164e-203 666.0
PYH2_k127_7477256_1 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 544.0
PYH2_k127_7477256_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 469.0
PYH2_k127_7477256_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 448.0
PYH2_k127_7477256_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000001347 181.0
PYH2_k127_7477256_5 nucleic acid-binding protein contains PIN domain K07066 - - 0.000000000000000000000000004076 116.0
PYH2_k127_7549916_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 362.0
PYH2_k127_7549916_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000007986 162.0
PYH2_k127_7549916_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000002243 78.0
PYH2_k127_7549916_3 - - - - 0.000000002875 59.0
PYH2_k127_7549916_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000002266 63.0
PYH2_k127_7549916_5 PFAM integrase family protein - - - 0.0000001749 55.0
PYH2_k127_7549916_6 - - - - 0.0007059 49.0
PYH2_k127_7554247_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001215 291.0
PYH2_k127_7554247_1 PFAM YcfA-like protein - - - 0.000000000000000000000000002367 113.0
PYH2_k127_7561406_0 Carboxypeptidase regulatory-like domain - - - 0.0 1124.0
PYH2_k127_7561406_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 590.0
PYH2_k127_7561406_2 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 559.0
PYH2_k127_7561406_3 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 402.0
PYH2_k127_7561406_4 Xylose isomerase domain protein TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 290.0
PYH2_k127_7561406_5 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004766 295.0
PYH2_k127_7561406_6 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000783 247.0
PYH2_k127_7561406_7 Protein conserved in bacteria K07011 - - 0.0000000000000000000000000000000000000000000000000000000002809 207.0
PYH2_k127_7561406_8 - - - - 0.0000000000000000000000000000000000000000000000003442 185.0
PYH2_k127_7569704_0 Hydrolase CocE NonD family - - - 0.0 1022.0
PYH2_k127_7569704_1 Carboxypeptidase regulatory-like domain - - - 3.03e-314 998.0
PYH2_k127_7569704_10 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 415.0
PYH2_k127_7569704_11 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 397.0
PYH2_k127_7569704_12 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 366.0
PYH2_k127_7569704_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
PYH2_k127_7569704_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 313.0
PYH2_k127_7569704_15 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 336.0
PYH2_k127_7569704_16 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000004289 274.0
PYH2_k127_7569704_17 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001941 225.0
PYH2_k127_7569704_18 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000001268 211.0
PYH2_k127_7569704_19 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000003369 209.0
PYH2_k127_7569704_2 CarboxypepD_reg-like domain - - - 2.86e-302 971.0
PYH2_k127_7569704_20 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000000000000000000007278 199.0
PYH2_k127_7569704_21 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000001369 196.0
PYH2_k127_7569704_22 cellulose binding - - - 0.00000000000000000000000000000000000000000000000005916 184.0
PYH2_k127_7569704_23 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000006078 169.0
PYH2_k127_7569704_24 - - - - 0.000000000000000000000000000000000000000002575 157.0
PYH2_k127_7569704_25 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000007215 144.0
PYH2_k127_7569704_26 Redoxin - - - 0.00000000000000000000000000000007656 139.0
PYH2_k127_7569704_27 domain, Protein - - - 0.00000000000000000000000000000008012 146.0
PYH2_k127_7569704_28 von Willebrand factor, type A - - - 0.000000000000000000000000001686 128.0
PYH2_k127_7569704_29 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000143 111.0
PYH2_k127_7569704_3 domain protein - - - 8.418e-227 747.0
PYH2_k127_7569704_30 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000000001955 107.0
PYH2_k127_7569704_31 - - - - 0.000000000000000000000007388 108.0
PYH2_k127_7569704_32 domain protein K14194 - - 0.000000000000004068 89.0
PYH2_k127_7569704_33 Transposase IS200 like - - - 0.000000000002556 77.0
PYH2_k127_7569704_34 PFAM transposase IS200-family protein K07491 - - 0.00000000002038 74.0
PYH2_k127_7569704_35 Carboxypeptidase regulatory-like domain - - - 0.0000000002467 74.0
PYH2_k127_7569704_37 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000003876 61.0
PYH2_k127_7569704_38 cellulase activity - - - 0.0009455 53.0
PYH2_k127_7569704_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.37e-212 675.0
PYH2_k127_7569704_5 Acyclic terpene utilisation family protein AtuA - - - 1.829e-199 630.0
PYH2_k127_7569704_6 cell adhesion involved in biofilm formation K13735,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 543.0
PYH2_k127_7569704_7 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 456.0
PYH2_k127_7569704_8 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 456.0
PYH2_k127_7569704_9 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 443.0
PYH2_k127_7577956_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1373.0
PYH2_k127_7577956_1 AcrB/AcrD/AcrF family - - - 0.0 1031.0
PYH2_k127_7577956_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 345.0
PYH2_k127_7577956_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 320.0
PYH2_k127_7577956_4 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
PYH2_k127_7577956_5 - - - - 0.0000000000005495 71.0
PYH2_k127_7577956_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0005322 47.0
PYH2_k127_7620750_0 Sodium:solute symporter family - - - 2.542e-276 863.0
PYH2_k127_7620750_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 604.0
PYH2_k127_7620750_10 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000005626 181.0
PYH2_k127_7620750_11 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000001985 155.0
PYH2_k127_7620750_12 response regulator - - - 0.0000000000000000000000000000000000000006248 156.0
PYH2_k127_7620750_13 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000013 139.0
PYH2_k127_7620750_14 phosphorelay signal transduction system K02437 - - 0.000000000000000000000002749 111.0
PYH2_k127_7620750_16 Multicopper oxidase K22350 - 1.16.3.3 0.000000566 54.0
PYH2_k127_7620750_17 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.0001514 48.0
PYH2_k127_7620750_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 560.0
PYH2_k127_7620750_3 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 543.0
PYH2_k127_7620750_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 467.0
PYH2_k127_7620750_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 452.0
PYH2_k127_7620750_6 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 436.0
PYH2_k127_7620750_7 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 365.0
PYH2_k127_7620750_8 4 iron, 4 sulfur cluster binding K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 303.0
PYH2_k127_7638960_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 4.797e-277 867.0
PYH2_k127_7638960_1 Carboxypeptidase regulatory-like domain - - - 6.925e-253 815.0
PYH2_k127_7638960_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 267.0
PYH2_k127_7638960_11 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
PYH2_k127_7638960_12 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009173 251.0
PYH2_k127_7638960_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004299 259.0
PYH2_k127_7638960_14 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
PYH2_k127_7638960_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002288 211.0
PYH2_k127_7638960_16 - - - - 0.00000000000000000000000000000000000000000000004134 175.0
PYH2_k127_7638960_17 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.000000000000000000000000000000000000000016 177.0
PYH2_k127_7638960_18 PFAM YcfA-like protein - - - 0.0000000000000000000000005317 104.0
PYH2_k127_7638960_19 - - - - 0.0000000000000000000000025 105.0
PYH2_k127_7638960_2 Lamin Tail Domain K07004 - - 2.698e-241 784.0
PYH2_k127_7638960_20 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000007841 101.0
PYH2_k127_7638960_21 AMP binding - - - 0.0000000000000000000008596 107.0
PYH2_k127_7638960_22 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001377 98.0
PYH2_k127_7638960_23 - - - - 0.000000000000000000003927 96.0
PYH2_k127_7638960_24 AMP binding K06149 - - 0.000000000000000000017 103.0
PYH2_k127_7638960_25 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000004113 97.0
PYH2_k127_7638960_26 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000001669 73.0
PYH2_k127_7638960_27 - - - - 0.0000000001329 64.0
PYH2_k127_7638960_28 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000006641 68.0
PYH2_k127_7638960_29 - - - - 0.0000001309 60.0
PYH2_k127_7638960_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 601.0
PYH2_k127_7638960_31 Phospholipase_D-nuclease N-terminal - - - 0.0002336 46.0
PYH2_k127_7638960_4 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 535.0
PYH2_k127_7638960_5 argininosuccinate lyase K01755,K14681 - 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 492.0
PYH2_k127_7638960_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 351.0
PYH2_k127_7638960_7 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 328.0
PYH2_k127_7638960_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
PYH2_k127_7638960_9 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001121 276.0
PYH2_k127_7734615_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 604.0
PYH2_k127_7734615_1 Ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 504.0
PYH2_k127_7734615_10 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000001026 120.0
PYH2_k127_7734615_11 COG0457 FOG TPR repeat - - - 0.0000000000000000003045 98.0
PYH2_k127_7734615_12 - - - - 0.0000000000003854 78.0
PYH2_k127_7734615_13 Zinc carboxypeptidase - - - 0.0000000009836 61.0
PYH2_k127_7734615_14 Aerotolerance regulator BatC - - - 0.0003502 49.0
PYH2_k127_7734615_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 416.0
PYH2_k127_7734615_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 387.0
PYH2_k127_7734615_4 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 381.0
PYH2_k127_7734615_5 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
PYH2_k127_7734615_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000007564 250.0
PYH2_k127_7734615_7 OmpA family - - - 0.00000000000000000000000000000000000000001236 159.0
PYH2_k127_7734615_8 TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family K19158 - - 0.00000000000000000000000000000000000149 140.0
PYH2_k127_7734615_9 Zinc carboxypeptidase - - - 0.00000000000000000000000000000002759 132.0
PYH2_k127_7786266_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 483.0
PYH2_k127_7786266_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000008515 152.0
PYH2_k127_7786266_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000005937 119.0
PYH2_k127_7851028_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1046.0
PYH2_k127_7851028_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.219e-249 791.0
PYH2_k127_7851028_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006109 276.0
PYH2_k127_7851028_11 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000002743 167.0
PYH2_k127_7851028_12 TIGRFAM TonB K03832 - - 0.0000000000000000000000000002091 124.0
PYH2_k127_7851028_13 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000002341 116.0
PYH2_k127_7851028_14 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000368 102.0
PYH2_k127_7851028_15 Preprotein translocase subunit YajC K03210 - - 0.000000000000000005718 89.0
PYH2_k127_7851028_16 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000849 89.0
PYH2_k127_7851028_17 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.000000000000005398 87.0
PYH2_k127_7851028_18 Tetratricopeptide repeat - - - 0.0000000003118 70.0
PYH2_k127_7851028_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 548.0
PYH2_k127_7851028_3 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 500.0
PYH2_k127_7851028_4 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 484.0
PYH2_k127_7851028_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 463.0
PYH2_k127_7851028_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 412.0
PYH2_k127_7851028_7 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 370.0
PYH2_k127_7851028_8 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 353.0
PYH2_k127_7851028_9 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
PYH2_k127_7874643_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 452.0
PYH2_k127_7874643_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 443.0
PYH2_k127_7874643_10 Cro/C1-type HTH DNA-binding domain - - - 0.0009685 48.0
PYH2_k127_7874643_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 408.0
PYH2_k127_7874643_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 400.0
PYH2_k127_7874643_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 392.0
PYH2_k127_7874643_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 306.0
PYH2_k127_7874643_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 295.0
PYH2_k127_7874643_7 MgtC family K07507 - - 0.0000000000000000000000000000007554 130.0
PYH2_k127_7874643_8 - - - - 0.0000000000000000000000000000114 125.0
PYH2_k127_7874643_9 Cold shock K03704 - - 0.0000000000000000000000005302 106.0
PYH2_k127_7876871_0 Amidohydrolase family - - - 0.0 1032.0
PYH2_k127_7876871_1 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 8.729e-285 892.0
PYH2_k127_7876871_10 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000008697 251.0
PYH2_k127_7876871_11 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000776 226.0
PYH2_k127_7876871_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
PYH2_k127_7876871_13 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000004837 217.0
PYH2_k127_7876871_14 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
PYH2_k127_7876871_15 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000009064 186.0
PYH2_k127_7876871_16 - - - - 0.00000000000000000000000000000000006453 144.0
PYH2_k127_7876871_17 Redoxin - - - 0.000000000000000000000000000000744 127.0
PYH2_k127_7876871_18 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000321 93.0
PYH2_k127_7876871_19 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000761 86.0
PYH2_k127_7876871_2 Secretion system protein K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 523.0
PYH2_k127_7876871_20 - - - - 0.0000000001969 69.0
PYH2_k127_7876871_21 - - - - 0.00027 48.0
PYH2_k127_7876871_3 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 509.0
PYH2_k127_7876871_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
PYH2_k127_7876871_5 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 385.0
PYH2_k127_7876871_6 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 346.0
PYH2_k127_7876871_7 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 304.0
PYH2_k127_7876871_8 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 308.0
PYH2_k127_7876871_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 257.0
PYH2_k127_7910255_0 Domain of unknown function (DUF5117) - - - 0.0 1097.0
PYH2_k127_7910255_1 proteins of the AP superfamily K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 449.0
PYH2_k127_7910255_10 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000004615 158.0
PYH2_k127_7910255_11 S1/P1 Nuclease - - - 0.000000000000000000000000000000001112 141.0
PYH2_k127_7910255_12 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000001692 138.0
PYH2_k127_7910255_13 DNA-templated transcription, initiation K03088 - - 0.000000000000000001456 91.0
PYH2_k127_7910255_14 Multicopper oxidase - - - 0.000000000000000004974 99.0
PYH2_k127_7910255_15 Roadblock/LC7 domain - - - 0.00000000000002273 78.0
PYH2_k127_7910255_16 - - - - 0.000000004078 67.0
PYH2_k127_7910255_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 378.0
PYH2_k127_7910255_3 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 319.0
PYH2_k127_7910255_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 273.0
PYH2_k127_7910255_5 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002878 240.0
PYH2_k127_7910255_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000001331 231.0
PYH2_k127_7910255_7 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000001205 231.0
PYH2_k127_7910255_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000001094 217.0
PYH2_k127_7910255_9 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000458 199.0
PYH2_k127_7914460_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 379.0
PYH2_k127_7914460_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004276 285.0
PYH2_k127_7914460_10 Tetratricopeptide repeats - - - 0.000000000000000000005559 108.0
PYH2_k127_7914460_11 Tetratricopeptide repeat - - - 0.000000000000001968 89.0
PYH2_k127_7914460_12 PFAM Transposase IS200-like K07491 - - 0.000000000002327 78.0
PYH2_k127_7914460_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001527 262.0
PYH2_k127_7914460_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
PYH2_k127_7914460_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000885 205.0
PYH2_k127_7914460_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000005846 182.0
PYH2_k127_7914460_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000001159 154.0
PYH2_k127_7914460_7 - - - - 0.000000000000000000000000000105 121.0
PYH2_k127_7914460_8 - - - - 0.0000000000000000000001988 104.0
PYH2_k127_7914460_9 Putative regulatory protein - - - 0.000000000000000000001853 98.0
PYH2_k127_7914527_0 cellulose binding - - - 1.997e-317 994.0
PYH2_k127_7942523_0 Dehydrogenase K00117 - 1.1.5.2 6.303e-226 712.0
PYH2_k127_7942523_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 2.795e-213 672.0
PYH2_k127_7942523_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000008719 216.0
PYH2_k127_7942523_11 PQQ-like domain - - - 0.000000000000000000000000000000000000000000264 175.0
PYH2_k127_7942523_13 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.000000000000000000000000007649 121.0
PYH2_k127_7942523_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 552.0
PYH2_k127_7942523_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 529.0
PYH2_k127_7942523_4 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 451.0
PYH2_k127_7942523_5 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 430.0
PYH2_k127_7942523_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 420.0
PYH2_k127_7942523_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 356.0
PYH2_k127_7942523_8 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 319.0
PYH2_k127_7942523_9 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003027 278.0
PYH2_k127_7957148_0 Domain of unknown function (DUF3471) - - - 4.042e-197 628.0
PYH2_k127_7957148_1 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000005555 239.0
PYH2_k127_7957469_0 Carboxypeptidase regulatory-like domain - - - 0.0 1067.0
PYH2_k127_7957469_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.37e-296 925.0
PYH2_k127_7957469_10 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 408.0
PYH2_k127_7957469_11 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 379.0
PYH2_k127_7957469_12 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
PYH2_k127_7957469_13 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 368.0
PYH2_k127_7957469_14 polyphosphate kinase activity K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 341.0
PYH2_k127_7957469_15 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 368.0
PYH2_k127_7957469_16 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 295.0
PYH2_k127_7957469_17 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 293.0
PYH2_k127_7957469_18 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004889 265.0
PYH2_k127_7957469_19 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000001236 266.0
PYH2_k127_7957469_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.12e-204 645.0
PYH2_k127_7957469_20 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004427 250.0
PYH2_k127_7957469_21 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000001441 256.0
PYH2_k127_7957469_22 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000003053 254.0
PYH2_k127_7957469_23 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.000000000000000000000000000000000000000000000000000000000000000000581 240.0
PYH2_k127_7957469_24 - - - - 0.00000000000000000000000000000000000000000000000000000001862 211.0
PYH2_k127_7957469_25 DinB superfamily - - - 0.000000000000000000000000000000000000000000004871 168.0
PYH2_k127_7957469_26 - - - - 0.00000000000000000000000000000000000000000003489 166.0
PYH2_k127_7957469_27 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000148 159.0
PYH2_k127_7957469_28 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000005608 145.0
PYH2_k127_7957469_29 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003077 139.0
PYH2_k127_7957469_3 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 576.0
PYH2_k127_7957469_30 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000002015 139.0
PYH2_k127_7957469_31 Transcriptional regulator - - - 0.00000000000000000000000000000000003626 138.0
PYH2_k127_7957469_32 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001793 131.0
PYH2_k127_7957469_33 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000002361 129.0
PYH2_k127_7957469_34 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000007505 125.0
PYH2_k127_7957469_35 GAF domain - - - 0.00000000000000000000000000005132 127.0
PYH2_k127_7957469_36 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000004808 132.0
PYH2_k127_7957469_37 competence protein - - - 0.000000000000000000000000004721 120.0
PYH2_k127_7957469_38 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000006032 111.0
PYH2_k127_7957469_39 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K11329 - - 0.000000000000000007163 97.0
PYH2_k127_7957469_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 556.0
PYH2_k127_7957469_40 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.00000000000000001461 94.0
PYH2_k127_7957469_41 SMART Tetratricopeptide domain protein - - - 0.0000000006372 71.0
PYH2_k127_7957469_42 PA14 domain - - - 0.0000000009155 70.0
PYH2_k127_7957469_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 546.0
PYH2_k127_7957469_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 456.0
PYH2_k127_7957469_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 459.0
PYH2_k127_7957469_8 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 427.0
PYH2_k127_7957469_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 421.0
PYH2_k127_7980532_0 Sortilin, neurotensin receptor 3, - - - 0.0 1134.0
PYH2_k127_7980532_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.656e-233 735.0
PYH2_k127_7980532_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 468.0
PYH2_k127_7980532_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 432.0
PYH2_k127_7980532_4 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 430.0
PYH2_k127_7980532_5 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 296.0
PYH2_k127_7980532_6 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.000000000000000000000000000000000000000000000000000000005875 201.0
PYH2_k127_7980532_7 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000008187 188.0
PYH2_k127_7980532_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000003317 185.0
PYH2_k127_8004995_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1109.0
PYH2_k127_8004995_1 C-terminus of AA_permease K03294 - - 1.001e-222 703.0
PYH2_k127_8004995_10 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 357.0
PYH2_k127_8004995_11 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 306.0
PYH2_k127_8004995_12 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 289.0
PYH2_k127_8004995_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
PYH2_k127_8004995_14 histone H2A K63-linked ubiquitination K00998,K06131 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003404 280.0
PYH2_k127_8004995_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004096 260.0
PYH2_k127_8004995_16 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000006155 250.0
PYH2_k127_8004995_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000214 192.0
PYH2_k127_8004995_19 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000004387 184.0
PYH2_k127_8004995_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.204e-203 646.0
PYH2_k127_8004995_20 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000005429 174.0
PYH2_k127_8004995_21 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000001064 143.0
PYH2_k127_8004995_22 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000004002 115.0
PYH2_k127_8004995_23 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.00000000000000000002775 101.0
PYH2_k127_8004995_24 GTP binding - - - 0.00000000000000002792 87.0
PYH2_k127_8004995_25 Protein of unknown function (DUF2752) - - - 0.000000000009607 72.0
PYH2_k127_8004995_26 PFAM Cyclic nucleotide-binding - - - 0.0000001055 62.0
PYH2_k127_8004995_28 Recombinase zinc beta ribbon domain K06400 - - 0.00001486 51.0
PYH2_k127_8004995_29 Outer membrane protein (OmpH-like) K06142 - - 0.0001602 53.0
PYH2_k127_8004995_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 614.0
PYH2_k127_8004995_30 Outer membrane protein (OmpH-like) K06142 - - 0.0001865 51.0
PYH2_k127_8004995_4 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 593.0
PYH2_k127_8004995_5 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 600.0
PYH2_k127_8004995_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 491.0
PYH2_k127_8004995_7 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 496.0
PYH2_k127_8004995_8 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 403.0
PYH2_k127_8004995_9 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 366.0
PYH2_k127_8099872_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1259.0
PYH2_k127_8099872_1 Asparagine synthase K01953 - 6.3.5.4 7.884e-277 865.0
PYH2_k127_8099872_10 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 343.0
PYH2_k127_8099872_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 310.0
PYH2_k127_8099872_12 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
PYH2_k127_8099872_13 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 289.0
PYH2_k127_8099872_14 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003081 287.0
PYH2_k127_8099872_15 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003901 263.0
PYH2_k127_8099872_16 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000002554 259.0
PYH2_k127_8099872_17 PFAM O-Antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000002425 245.0
PYH2_k127_8099872_18 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000000000000003272 200.0
PYH2_k127_8099872_19 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000369 184.0
PYH2_k127_8099872_2 Sulfate permease family - - - 1.916e-206 651.0
PYH2_k127_8099872_20 chlorophyll binding - - - 0.00000000000000000000000000000000000000000001174 176.0
PYH2_k127_8099872_21 - - - - 0.0000000000000000000000000000000000000000000964 177.0
PYH2_k127_8099872_22 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000000001971 120.0
PYH2_k127_8099872_23 - - - - 0.000006057 49.0
PYH2_k127_8099872_25 TPR repeat - - - 0.00003893 56.0
PYH2_k127_8099872_26 Belongs to the 'phage' integrase family - - - 0.0007303 48.0
PYH2_k127_8099872_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 547.0
PYH2_k127_8099872_4 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 475.0
PYH2_k127_8099872_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 471.0
PYH2_k127_8099872_6 TIGRFAM integral membrane protein MviN K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 422.0
PYH2_k127_8099872_7 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 407.0
PYH2_k127_8099872_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 379.0
PYH2_k127_8099872_9 glycosyl transferase group 1 K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 340.0
PYH2_k127_8194252_0 radical SAM domain protein - - - 1.399e-228 717.0
PYH2_k127_8194252_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 446.0
PYH2_k127_8194252_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 333.0
PYH2_k127_8194252_3 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 308.0
PYH2_k127_8194252_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 310.0
PYH2_k127_8194252_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001009 270.0
PYH2_k127_8194252_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000229 273.0
PYH2_k127_8194252_7 HAD-superfamily hydrolase, subfamily IA K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000005839 160.0
PYH2_k127_8194252_8 Belongs to the 5'-nucleotidase family - - - 0.00001172 57.0
PYH2_k127_8194407_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 479.0
PYH2_k127_8194407_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
PYH2_k127_8194407_2 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 416.0
PYH2_k127_8194407_3 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 353.0
PYH2_k127_8194407_4 Protein of unknown function (DUF2911) - - - 0.0000000000000000005243 94.0
PYH2_k127_8194407_5 -O-antigen K02847 - - 0.00008276 55.0
PYH2_k127_820715_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 3.716e-223 703.0
PYH2_k127_820715_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
PYH2_k127_820715_10 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000134 179.0
PYH2_k127_820715_11 Phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000005187 178.0
PYH2_k127_820715_12 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000007245 165.0
PYH2_k127_820715_13 Yip1 domain - - - 0.00000000000000000007147 100.0
PYH2_k127_820715_14 phosphatidylinositol metabolic process K13671 - - 0.000000005444 68.0
PYH2_k127_820715_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 389.0
PYH2_k127_820715_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 363.0
PYH2_k127_820715_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 351.0
PYH2_k127_820715_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 321.0
PYH2_k127_820715_6 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000008771 246.0
PYH2_k127_820715_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000146 229.0
PYH2_k127_820715_8 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000001496 211.0
PYH2_k127_820715_9 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000007467 182.0
PYH2_k127_8270830_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 510.0
PYH2_k127_8270830_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 439.0
PYH2_k127_8270830_10 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000000006401 246.0
PYH2_k127_8270830_11 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000002355 244.0
PYH2_k127_8270830_12 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000001328 234.0
PYH2_k127_8270830_13 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000001169 234.0
PYH2_k127_8270830_14 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000001048 226.0
PYH2_k127_8270830_15 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000001007 218.0
PYH2_k127_8270830_16 PFAM Peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000001109 223.0
PYH2_k127_8270830_17 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000001576 213.0
PYH2_k127_8270830_18 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000009641 179.0
PYH2_k127_8270830_19 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000001398 176.0
PYH2_k127_8270830_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 435.0
PYH2_k127_8270830_20 Small Multidrug Resistance protein K03297,K11741 - - 0.000000000000000000000000000000000000000007349 160.0
PYH2_k127_8270830_21 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000000000005749 150.0
PYH2_k127_8270830_22 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000004723 147.0
PYH2_k127_8270830_23 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000000788 116.0
PYH2_k127_8270830_24 PFAM von Willebrand factor type A - - - 0.000000000000000000000000002432 124.0
PYH2_k127_8270830_25 mRNA binding - - - 0.0000000000000000007337 87.0
PYH2_k127_8270830_26 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000002647 87.0
PYH2_k127_8270830_27 F420-dependent enzyme K07005 - - 0.000004771 55.0
PYH2_k127_8270830_28 deoxyhypusine monooxygenase activity - - - 0.00003397 56.0
PYH2_k127_8270830_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 422.0
PYH2_k127_8270830_4 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 413.0
PYH2_k127_8270830_5 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 417.0
PYH2_k127_8270830_6 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 412.0
PYH2_k127_8270830_7 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
PYH2_k127_8270830_8 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005595 256.0
PYH2_k127_8270830_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
PYH2_k127_8288212_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 536.0
PYH2_k127_8288212_1 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 456.0
PYH2_k127_8288212_2 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 444.0
PYH2_k127_8288212_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 328.0
PYH2_k127_8288212_4 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 322.0
PYH2_k127_8288212_5 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 307.0
PYH2_k127_8288212_6 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 291.0
PYH2_k127_8288212_7 G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 269.0
PYH2_k127_8288212_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002916 269.0
PYH2_k127_8288212_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0002294 44.0
PYH2_k127_8400448_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 3.019e-320 1007.0
PYH2_k127_8400448_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 332.0
PYH2_k127_8400448_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000001811 221.0
PYH2_k127_8400448_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000005773 120.0
PYH2_k127_8400448_5 general stress protein - - - 0.0000009634 57.0
PYH2_k127_8528061_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 605.0
PYH2_k127_8528061_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 407.0
PYH2_k127_8528061_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 259.0
PYH2_k127_8528061_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000002025 243.0
PYH2_k127_8528061_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000004961 218.0
PYH2_k127_8528061_5 amidohydrolase - - - 0.0000000000000000000000000000000002918 136.0
PYH2_k127_8528061_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000002377 128.0
PYH2_k127_8528061_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000001533 76.0
PYH2_k127_8528061_8 viral genome integration into host DNA - - - 0.000001944 59.0
PYH2_k127_8528061_9 - - - - 0.0002033 46.0
PYH2_k127_8548219_0 - - - - 8.365e-207 667.0
PYH2_k127_8548219_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 355.0
PYH2_k127_8548219_10 ECF sigma factor - - - 0.0000000000000000000000000000000000008948 145.0
PYH2_k127_8548219_11 - - - - 0.000000000000000000000000000003132 128.0
PYH2_k127_8548219_12 PAP2 superfamily - - - 0.00000000000000000000009427 110.0
PYH2_k127_8548219_13 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000002387 92.0
PYH2_k127_8548219_14 - - - - 0.00000000000000001564 85.0
PYH2_k127_8548219_15 Domain of unknown function (DUF4149) - - - 0.0000000000000001616 86.0
PYH2_k127_8548219_16 Cupin 2, conserved barrel domain protein - - - 0.00000006025 58.0
PYH2_k127_8548219_17 - - - - 0.0003329 49.0
PYH2_k127_8548219_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 335.0
PYH2_k127_8548219_3 Lanthionine synthetase C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 327.0
PYH2_k127_8548219_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 264.0
PYH2_k127_8548219_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
PYH2_k127_8548219_6 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000007734 232.0
PYH2_k127_8548219_7 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000004277 232.0
PYH2_k127_8548219_8 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001986 226.0
PYH2_k127_8548219_9 - - - - 0.000000000000000000000000000000000000000000000005739 183.0
PYH2_k127_8550847_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002991 281.0
PYH2_k127_8550847_1 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000002485 191.0
PYH2_k127_8552433_0 carboxylic acid catabolic process K01187 - 3.2.1.20 1.958e-270 846.0
PYH2_k127_8552433_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 392.0
PYH2_k127_8552433_2 D-galactarate dehydratase Altronate K01685,K01708 - 4.2.1.42,4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 385.0
PYH2_k127_8552433_3 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
PYH2_k127_8552433_4 oxidation-reduction process K00826 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0006706,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0010817,GO:0016042,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0042445,GO:0042446,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0047045,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
PYH2_k127_8552433_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001933 237.0
PYH2_k127_8552433_6 YjbR - - - 0.0000000000000000000000000000006304 129.0
PYH2_k127_8552433_7 GDSL-like Lipase/Acylhydrolase family - - - 0.000001215 54.0
PYH2_k127_855373_0 FtsX-like permease family - - - 1.241e-244 785.0
PYH2_k127_855373_1 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.987e-234 747.0
PYH2_k127_855373_10 Protein of unknown function (DUF433) - - - 0.0000000000000000000000001207 109.0
PYH2_k127_855373_11 MacB-like periplasmic core domain - - - 0.000000000000000000001022 97.0
PYH2_k127_855373_12 MacB-like periplasmic core domain - - - 0.00002568 49.0
PYH2_k127_855373_13 - - - - 0.00003241 48.0
PYH2_k127_855373_14 MacB-like periplasmic core domain - - - 0.0005491 44.0
PYH2_k127_855373_2 FtsX-like permease family - - - 1.006e-206 675.0
PYH2_k127_855373_3 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 533.0
PYH2_k127_855373_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 341.0
PYH2_k127_855373_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
PYH2_k127_855373_6 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000007724 164.0
PYH2_k127_855373_7 - - - - 0.000000000000000000000000000000000000002093 163.0
PYH2_k127_855373_8 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000005097 143.0
PYH2_k127_855373_9 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000001965 134.0
PYH2_k127_8561282_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 633.0
PYH2_k127_8561282_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 527.0
PYH2_k127_8561282_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000001255 201.0
PYH2_k127_8561282_11 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000002202 197.0
PYH2_k127_8561282_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000001355 176.0
PYH2_k127_8561282_13 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000001706 164.0
PYH2_k127_8561282_14 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000000000000000000000000000001271 158.0
PYH2_k127_8561282_15 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000002701 171.0
PYH2_k127_8561282_16 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000216 145.0
PYH2_k127_8561282_17 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000001246 121.0
PYH2_k127_8561282_18 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000006875 123.0
PYH2_k127_8561282_19 mRNA binding - - - 0.00000000000000000000000002872 109.0
PYH2_k127_8561282_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 509.0
PYH2_k127_8561282_20 - - - - 0.000000000000003067 83.0
PYH2_k127_8561282_21 EF-hand domain - - - 0.000000001176 68.0
PYH2_k127_8561282_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 456.0
PYH2_k127_8561282_4 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 382.0
PYH2_k127_8561282_5 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 334.0
PYH2_k127_8561282_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 311.0
PYH2_k127_8561282_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 302.0
PYH2_k127_8561282_8 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001357 270.0
PYH2_k127_8561282_9 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
PYH2_k127_8574771_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 2.43e-321 988.0
PYH2_k127_8574771_1 PFAM HypF finger K04656 - - 3.553e-285 896.0
PYH2_k127_8574771_10 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 486.0
PYH2_k127_8574771_11 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 396.0
PYH2_k127_8574771_12 ImcF-related N-terminal domain K11891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 412.0
PYH2_k127_8574771_13 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 373.0
PYH2_k127_8574771_14 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 365.0
PYH2_k127_8574771_15 type VI secretion protein, VC_A0114 family K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 352.0
PYH2_k127_8574771_16 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 332.0
PYH2_k127_8574771_17 type VI secretion protein, VC_A0111 family K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
PYH2_k127_8574771_18 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 307.0
PYH2_k127_8574771_19 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 288.0
PYH2_k127_8574771_2 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 7.135e-229 717.0
PYH2_k127_8574771_20 Protein conserved in bacteria K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000183 268.0
PYH2_k127_8574771_21 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
PYH2_k127_8574771_22 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
PYH2_k127_8574771_23 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003789 246.0
PYH2_k127_8574771_24 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005518 252.0
PYH2_k127_8574771_25 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005187 243.0
PYH2_k127_8574771_26 type VI secretion protein K11901 - - 0.0000000000000000000000000000000000000000000000000000000000008776 215.0
PYH2_k127_8574771_27 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000006291 191.0
PYH2_k127_8574771_28 - - - - 0.0000000000000000000000000000000000000000000000000001911 193.0
PYH2_k127_8574771_29 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000000003146 187.0
PYH2_k127_8574771_3 TIGRFAM type VI secretion protein, VC_A0110 family K11896 - - 4.644e-213 679.0
PYH2_k127_8574771_30 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000302 177.0
PYH2_k127_8574771_31 - - - - 0.00000000000000000000000000000000000000000001218 165.0
PYH2_k127_8574771_32 spore germination K03605 - - 0.0000000000000000000000000000000000000000001411 165.0
PYH2_k127_8574771_33 - - - - 0.000000000000000000000000000000000000000000349 162.0
PYH2_k127_8574771_34 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000006345 147.0
PYH2_k127_8574771_35 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000261 161.0
PYH2_k127_8574771_36 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000000000007222 148.0
PYH2_k127_8574771_37 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000002677 139.0
PYH2_k127_8574771_38 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000002465 131.0
PYH2_k127_8574771_39 Erythromycin esterase - - - 0.00000000000000000000000000001801 120.0
PYH2_k127_8574771_4 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 606.0
PYH2_k127_8574771_40 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000000002122 116.0
PYH2_k127_8574771_41 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000002828 111.0
PYH2_k127_8574771_42 YCII-related domain - - - 0.000000000000000000000004227 115.0
PYH2_k127_8574771_43 - - - - 0.00000000000000000000004839 110.0
PYH2_k127_8574771_44 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000009645 101.0
PYH2_k127_8574771_45 Domain of unknown function (DU1801) - - - 0.0000000000000000000001468 102.0
PYH2_k127_8574771_46 TIGRFAM type VI secretion ATPase, ClpV1 family K11907 - - 0.000000000000000000001524 93.0
PYH2_k127_8574771_47 SMART Transport-associated and nodulation region - - - 0.000000000000000007109 91.0
PYH2_k127_8574771_48 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.00000000000001371 86.0
PYH2_k127_8574771_49 PFAM Lytic transglycosylase catalytic K08307 - - 0.00000000000001869 86.0
PYH2_k127_8574771_5 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 603.0
PYH2_k127_8574771_50 - - - - 0.0000000002999 63.0
PYH2_k127_8574771_51 Domain of unknown function (DUF4384) - - - 0.0000000005655 69.0
PYH2_k127_8574771_52 FHA domain - - - 0.0000000009102 71.0
PYH2_k127_8574771_53 Polyphosphate kinase 2 (PPK2) - - - 0.000000002655 60.0
PYH2_k127_8574771_54 - - - - 0.000000005577 63.0
PYH2_k127_8574771_55 Forkhead associated domain - - - 0.00000002774 66.0
PYH2_k127_8574771_56 Domain of unknown function (DUF4384) - - - 0.00000004106 64.0
PYH2_k127_8574771_57 Protein conserved in bacteria - - - 0.00000004563 59.0
PYH2_k127_8574771_58 - - - - 0.0000001229 53.0
PYH2_k127_8574771_59 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000002399 63.0
PYH2_k127_8574771_6 oligopeptide transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 566.0
PYH2_k127_8574771_60 Belongs to the universal stress protein A family - - - 0.0000003811 61.0
PYH2_k127_8574771_7 Protein of unknown function (DUF692) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 535.0
PYH2_k127_8574771_8 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 512.0
PYH2_k127_8574771_9 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 511.0
PYH2_k127_8583428_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 592.0
PYH2_k127_8583428_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 312.0
PYH2_k127_8583428_2 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000001958 192.0
PYH2_k127_8583428_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000002417 193.0
PYH2_k127_8583428_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000007392 176.0
PYH2_k127_8583428_5 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000008591 186.0
PYH2_k127_8583428_6 Biotin-requiring enzyme - - - 0.00000000000000000000000002672 116.0
PYH2_k127_8583428_7 general secretion pathway protein G K02456 - - 0.00006221 53.0
PYH2_k127_8583428_8 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0001268 44.0
PYH2_k127_8583428_9 Protein of unknown function (DUF3225) - - - 0.0006758 48.0
PYH2_k127_8586745_0 cellulose binding - - - 0.0 1208.0
PYH2_k127_8586745_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1118.0
PYH2_k127_8586745_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 278.0
PYH2_k127_8586745_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000006005 183.0
PYH2_k127_8586745_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000002172 173.0
PYH2_k127_8586745_5 Thioredoxin - - - 0.00000000000000000002128 106.0
PYH2_k127_8605957_0 serine-type peptidase activity - - - 0.0 1152.0
PYH2_k127_8605957_1 Carboxypeptidase regulatory-like domain - - - 1.218e-316 1005.0
PYH2_k127_8605957_10 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
PYH2_k127_8605957_11 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000005477 254.0
PYH2_k127_8605957_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
PYH2_k127_8605957_13 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000001008 183.0
PYH2_k127_8605957_14 - - - - 0.00000000000000000000000000000001393 134.0
PYH2_k127_8605957_15 O-methyltransferase K00588 - 2.1.1.104 0.0000000000003683 70.0
PYH2_k127_8605957_16 - - - - 0.000000006599 58.0
PYH2_k127_8605957_17 - - - - 0.000008726 53.0
PYH2_k127_8605957_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0003061 43.0
PYH2_k127_8605957_2 beta-lactamase - - - 2.592e-255 812.0
PYH2_k127_8605957_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.258e-227 712.0
PYH2_k127_8605957_4 IgA Peptidase M64 - - - 3.887e-216 679.0
PYH2_k127_8605957_5 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 2.377e-202 642.0
PYH2_k127_8605957_6 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.862e-199 645.0
PYH2_k127_8605957_7 Phosphotriesterase K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 550.0
PYH2_k127_8605957_8 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 445.0
PYH2_k127_8605957_9 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 412.0
PYH2_k127_8620058_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.293e-297 932.0
PYH2_k127_8620058_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 565.0
PYH2_k127_8620058_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
PYH2_k127_8620058_11 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000006821 242.0
PYH2_k127_8620058_12 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000004776 235.0
PYH2_k127_8620058_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
PYH2_k127_8620058_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000003127 216.0
PYH2_k127_8620058_15 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000001648 205.0
PYH2_k127_8620058_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000003185 205.0
PYH2_k127_8620058_17 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000002144 177.0
PYH2_k127_8620058_18 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000004127 174.0
PYH2_k127_8620058_19 Cupin - - - 0.000000000000000000000000000000007978 130.0
PYH2_k127_8620058_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 481.0
PYH2_k127_8620058_20 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000001306 132.0
PYH2_k127_8620058_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000001357 123.0
PYH2_k127_8620058_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000002296 128.0
PYH2_k127_8620058_23 Putative adhesin - - - 0.000000000000000000000000042 124.0
PYH2_k127_8620058_24 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.000000000000000000000000114 108.0
PYH2_k127_8620058_25 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000001995 111.0
PYH2_k127_8620058_26 acetyltransferase - - - 0.00000000000000005732 86.0
PYH2_k127_8620058_27 Domain of unknown function (DUF3883) - - - 0.000000000001214 72.0
PYH2_k127_8620058_28 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000001369 66.0
PYH2_k127_8620058_29 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000001695 69.0
PYH2_k127_8620058_3 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 450.0
PYH2_k127_8620058_30 - - - - 0.00000000269 67.0
PYH2_k127_8620058_31 YoeB-like toxin of bacterial type II toxin-antitoxin system K19158 - - 0.000003549 49.0
PYH2_k127_8620058_4 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 426.0
PYH2_k127_8620058_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 394.0
PYH2_k127_8620058_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 365.0
PYH2_k127_8620058_7 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 346.0
PYH2_k127_8620058_8 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 282.0
PYH2_k127_8620058_9 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006718 289.0
PYH2_k127_8634546_0 Carboxypeptidase regulatory-like domain - - - 9.01e-255 810.0
PYH2_k127_8634546_1 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 1.834e-201 649.0
PYH2_k127_8634546_10 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 369.0
PYH2_k127_8634546_11 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000002067 253.0
PYH2_k127_8634546_12 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000529 237.0
PYH2_k127_8634546_13 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000007823 233.0
PYH2_k127_8634546_14 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001148 212.0
PYH2_k127_8634546_15 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000008879 200.0
PYH2_k127_8634546_16 Polysaccharide pyruvyl transferase, CsaB - - - 0.000000000000000000000000000000000000000000001026 193.0
PYH2_k127_8634546_17 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000003189 158.0
PYH2_k127_8634546_18 amine dehydrogenase activity - - - 0.0000000000000000000000000000000007079 146.0
PYH2_k127_8634546_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000002309 138.0
PYH2_k127_8634546_2 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 578.0
PYH2_k127_8634546_20 Multicopper oxidase K22350 - 1.16.3.3 0.00000000000000000000000000000007755 144.0
PYH2_k127_8634546_21 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000007746 127.0
PYH2_k127_8634546_22 Metallo-peptidase family M12 - - - 0.00000000000000000000000000001546 137.0
PYH2_k127_8634546_23 dextransucrase activity - - - 0.0000000000000000000000000005342 132.0
PYH2_k127_8634546_24 RNA recognition motif - - - 0.00000000000000000000000001007 115.0
PYH2_k127_8634546_25 amine dehydrogenase activity - - - 0.00000000000000000000000001477 123.0
PYH2_k127_8634546_26 beta-propeller repeat - - - 0.0000000000000000000002275 102.0
PYH2_k127_8634546_27 - - - - 0.000000000000000000002256 102.0
PYH2_k127_8634546_28 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000001129 96.0
PYH2_k127_8634546_29 amine dehydrogenase activity - - - 0.000000000000000589 84.0
PYH2_k127_8634546_3 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 585.0
PYH2_k127_8634546_30 Cytochrome c554 and c-prime - - - 0.00000000000001081 85.0
PYH2_k127_8634546_31 Ami_2 - - - 0.000000000002225 81.0
PYH2_k127_8634546_32 - - - - 0.000000003542 58.0
PYH2_k127_8634546_33 dextransucrase activity - - - 0.00000003128 55.0
PYH2_k127_8634546_34 phosphatase activity - - - 0.0000005235 62.0
PYH2_k127_8634546_35 Multicopper oxidase K22350 - 1.16.3.3 0.00001043 51.0
PYH2_k127_8634546_36 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042182,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046872,GO:0046914,GO:0051186,GO:0051596,GO:0061727,GO:0071704,GO:1901564,GO:1901575,GO:1901615 4.4.1.5 0.00001431 57.0
PYH2_k127_8634546_37 Belongs to the 5'-nucleotidase family K01081,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00004813 55.0
PYH2_k127_8634546_38 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00007671 46.0
PYH2_k127_8634546_39 Parallel beta-helix repeats - - - 0.0001075 47.0
PYH2_k127_8634546_4 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 433.0
PYH2_k127_8634546_40 5'-nucleotidase, C-terminal domain K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0002471 53.0
PYH2_k127_8634546_41 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0004933 52.0
PYH2_k127_8634546_5 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 439.0
PYH2_k127_8634546_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 417.0
PYH2_k127_8634546_7 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 389.0
PYH2_k127_8634546_8 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 379.0
PYH2_k127_8634546_9 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 349.0
PYH2_k127_8637220_0 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 451.0
PYH2_k127_8637220_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 293.0
PYH2_k127_8637220_2 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000006801 189.0
PYH2_k127_8637220_3 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000001453 190.0
PYH2_k127_8637220_4 protein TIM barrel - - - 0.0000000000000000000000000000003166 138.0
PYH2_k127_8681406_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1138.0
PYH2_k127_8681406_1 Dienelactone hydrolase family - - - 6.191e-298 928.0
PYH2_k127_8681406_10 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 349.0
PYH2_k127_8681406_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 338.0
PYH2_k127_8681406_12 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 304.0
PYH2_k127_8681406_13 Domain of unknown function (DUF4432) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003023 280.0
PYH2_k127_8681406_14 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000002331 235.0
PYH2_k127_8681406_15 Indolepyruvate K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
PYH2_k127_8681406_16 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000004026 174.0
PYH2_k127_8681406_17 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000005811 174.0
PYH2_k127_8681406_18 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000006214 159.0
PYH2_k127_8681406_19 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000004574 167.0
PYH2_k127_8681406_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 2.296e-198 631.0
PYH2_k127_8681406_20 TIGRFAM Outer membrane protein K13735,K20276 - - 0.000000000000000000000000000000000000005091 155.0
PYH2_k127_8681406_21 Psort location Cytoplasmic, score 8.96 K03653 - 4.2.99.18 0.00000000000000000000000000000000006281 142.0
PYH2_k127_8681406_22 acid phosphatase activity - - - 0.0000000000000000000000000000009818 131.0
PYH2_k127_8681406_23 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000846 112.0
PYH2_k127_8681406_24 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000008777 106.0
PYH2_k127_8681406_25 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000001805 106.0
PYH2_k127_8681406_26 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000002553 113.0
PYH2_k127_8681406_27 PIN domain - - - 0.0000000000000000000001718 102.0
PYH2_k127_8681406_28 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000007315 105.0
PYH2_k127_8681406_29 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000004596 92.0
PYH2_k127_8681406_3 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 606.0
PYH2_k127_8681406_30 3D domain protein - - - 0.0000000000001165 80.0
PYH2_k127_8681406_31 Tetratricopeptide repeat - - - 0.0000000000001336 84.0
PYH2_k127_8681406_32 Tetratricopeptide repeat - - - 0.0000000000001741 78.0
PYH2_k127_8681406_33 peptidyl-tyrosine sulfation - - - 0.00000001229 66.0
PYH2_k127_8681406_4 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 539.0
PYH2_k127_8681406_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 511.0
PYH2_k127_8681406_6 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 488.0
PYH2_k127_8681406_7 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 451.0
PYH2_k127_8681406_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 466.0
PYH2_k127_8681406_9 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 405.0
PYH2_k127_8691207_0 Amino acid adenylation domain - - - 0.0 1434.0
PYH2_k127_8691207_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 3.807e-283 891.0
PYH2_k127_8691207_10 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 327.0
PYH2_k127_8691207_11 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 347.0
PYH2_k127_8691207_12 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 303.0
PYH2_k127_8691207_13 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 291.0
PYH2_k127_8691207_14 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004096 286.0
PYH2_k127_8691207_15 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000575 225.0
PYH2_k127_8691207_16 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000002495 210.0
PYH2_k127_8691207_17 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000000000000000000000005401 185.0
PYH2_k127_8691207_18 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000002556 167.0
PYH2_k127_8691207_19 DNA integration - - - 0.00000000000000000000000000000000001504 136.0
PYH2_k127_8691207_2 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity K01928,K03802 - 6.3.2.13,6.3.2.29,6.3.2.30 2.844e-267 848.0
PYH2_k127_8691207_20 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000587 103.0
PYH2_k127_8691207_21 amine dehydrogenase activity - - - 0.000000000000000000001013 101.0
PYH2_k127_8691207_22 RDD family - - - 0.00000000001933 76.0
PYH2_k127_8691207_23 sequence-specific DNA binding - - - 0.0000006092 57.0
PYH2_k127_8691207_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 8.778e-199 637.0
PYH2_k127_8691207_4 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 530.0
PYH2_k127_8691207_5 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 503.0
PYH2_k127_8691207_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 481.0
PYH2_k127_8691207_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 380.0
PYH2_k127_8691207_8 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 353.0
PYH2_k127_8691207_9 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 349.0
PYH2_k127_8727173_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 605.0
PYH2_k127_8727173_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000491 236.0
PYH2_k127_8730009_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 8.364e-267 852.0
PYH2_k127_8730009_1 Dehydrogenase E1 component K11381 - 1.2.4.4 8.743e-263 828.0
PYH2_k127_8730009_10 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 384.0
PYH2_k127_8730009_11 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 381.0
PYH2_k127_8730009_12 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 378.0
PYH2_k127_8730009_13 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 361.0
PYH2_k127_8730009_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 350.0
PYH2_k127_8730009_15 Peptidase M36 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 340.0
PYH2_k127_8730009_16 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 297.0
PYH2_k127_8730009_17 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006263 292.0
PYH2_k127_8730009_18 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000709 271.0
PYH2_k127_8730009_19 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000002045 214.0
PYH2_k127_8730009_2 Sulfatase K01130 - 3.1.6.1 4.254e-260 823.0
PYH2_k127_8730009_20 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000002138 195.0
PYH2_k127_8730009_21 Subtilase family - - - 0.00000000000000000000000000000000000000000000008838 179.0
PYH2_k127_8730009_22 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000008651 177.0
PYH2_k127_8730009_23 PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000001342 166.0
PYH2_k127_8730009_24 CYTH - - - 0.0000000004951 71.0
PYH2_k127_8730009_25 DsrE/DsrF-like family - - - 0.000006076 56.0
PYH2_k127_8730009_26 DsrE/DsrF-like family - - - 0.0003116 44.0
PYH2_k127_8730009_27 Transport permease protein K01992 - - 0.0006373 44.0
PYH2_k127_8730009_3 Sulfatase - - - 2.205e-251 788.0
PYH2_k127_8730009_4 4Fe-4S single cluster domain K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 590.0
PYH2_k127_8730009_5 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 564.0
PYH2_k127_8730009_6 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 490.0
PYH2_k127_8730009_7 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 432.0
PYH2_k127_8730009_8 magnesium chelatase K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 428.0
PYH2_k127_8730009_9 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 434.0
PYH2_k127_8739817_0 Tricorn protease C1 domain K08676 - - 0.0 1336.0
PYH2_k127_8739817_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 5.626e-306 969.0
PYH2_k127_8739817_10 Protein of unknown function (DUF2911) - - - 0.00001788 55.0
PYH2_k127_8739817_2 Alkyl sulfatase dimerisation - - - 2.268e-194 625.0
PYH2_k127_8739817_3 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 467.0
PYH2_k127_8739817_4 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004463 269.0
PYH2_k127_8739817_5 Predicted Zn-dependent protease (DUF2268) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009529 278.0
PYH2_k127_8739817_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000101 234.0
PYH2_k127_8739817_7 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.00000000000000000000000000000000000000000000000000000007306 211.0
PYH2_k127_8739817_8 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000000000000000000000000000000000000000000001151 193.0
PYH2_k127_8739817_9 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000003387 156.0
PYH2_k127_8747573_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.999e-312 974.0
PYH2_k127_8747573_1 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 617.0
PYH2_k127_8747573_10 DinB superfamily - - - 0.000000000000002759 83.0
PYH2_k127_8747573_11 - - - - 0.0000001615 63.0
PYH2_k127_8747573_12 Outer membrane lipoprotein - - - 0.000003709 58.0
PYH2_k127_8747573_2 Serine aminopeptidase, S33 K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 304.0
PYH2_k127_8747573_3 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
PYH2_k127_8747573_4 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 307.0
PYH2_k127_8747573_5 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000001455 220.0
PYH2_k127_8747573_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000003255 213.0
PYH2_k127_8747573_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000007538 137.0
PYH2_k127_8747573_8 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.00000000000000000000000001482 117.0
PYH2_k127_8747573_9 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000000000000000001949 108.0
PYH2_k127_8758824_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 496.0
PYH2_k127_8758824_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 382.0
PYH2_k127_8758824_2 - - - - 0.000000001674 62.0
PYH2_k127_8778748_0 TonB-dependent receptor - - - 7.084e-236 765.0
PYH2_k127_8778748_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 532.0
PYH2_k127_8778748_10 spore germination - - - 0.000000000000000000000000000000001083 134.0
PYH2_k127_8778748_11 in signal transduction K08482 - - 0.0000000007983 71.0
PYH2_k127_8778748_12 regulation of DNA repair K03565 GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0006282,GO:0008150,GO:0016020,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.000001428 58.0
PYH2_k127_8778748_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 500.0
PYH2_k127_8778748_3 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 408.0
PYH2_k127_8778748_4 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 381.0
PYH2_k127_8778748_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 333.0
PYH2_k127_8778748_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
PYH2_k127_8778748_7 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000001124 220.0
PYH2_k127_8778748_8 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000008062 213.0
PYH2_k127_8778748_9 membrane K08978 - - 0.0000000000000000000000000000000002305 136.0
PYH2_k127_8784538_0 PFAM Type II secretion system protein E K02652 - - 2.163e-211 670.0
PYH2_k127_8784538_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 584.0
PYH2_k127_8784538_10 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 337.0
PYH2_k127_8784538_11 Sigma-54 dependent transcriptional regulator K14414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 284.0
PYH2_k127_8784538_12 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001385 283.0
PYH2_k127_8784538_13 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005288 276.0
PYH2_k127_8784538_14 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 279.0
PYH2_k127_8784538_15 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007072 274.0
PYH2_k127_8784538_16 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000002003 244.0
PYH2_k127_8784538_17 Putative Ig domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002159 251.0
PYH2_k127_8784538_18 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000008147 207.0
PYH2_k127_8784538_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000001547 203.0
PYH2_k127_8784538_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 557.0
PYH2_k127_8784538_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000001652 220.0
PYH2_k127_8784538_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001302 191.0
PYH2_k127_8784538_22 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000004407 193.0
PYH2_k127_8784538_23 Subtilase family - - - 0.0000000000000000000000000000000000000000000000003922 201.0
PYH2_k127_8784538_24 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000002431 181.0
PYH2_k127_8784538_25 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000006035 179.0
PYH2_k127_8784538_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000002697 178.0
PYH2_k127_8784538_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000001339 166.0
PYH2_k127_8784538_28 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000002438 151.0
PYH2_k127_8784538_29 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000004074 142.0
PYH2_k127_8784538_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 537.0
PYH2_k127_8784538_30 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000001018 137.0
PYH2_k127_8784538_31 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000002515 137.0
PYH2_k127_8784538_32 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000001656 131.0
PYH2_k127_8784538_33 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000004984 117.0
PYH2_k127_8784538_34 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.00000000000000000000000005674 113.0
PYH2_k127_8784538_35 General secretion pathway protein K02453 - - 0.00000000000000000001941 108.0
PYH2_k127_8784538_36 Polymer-forming cytoskeletal - - - 0.000000000000000000131 95.0
PYH2_k127_8784538_37 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000001688 100.0
PYH2_k127_8784538_38 Tetratricopeptide repeat - - - 0.00000000000000006411 94.0
PYH2_k127_8784538_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 518.0
PYH2_k127_8784538_40 Pilus assembly protein K02662 - - 0.00000006776 64.0
PYH2_k127_8784538_41 Protein of unknown function (DUF465) - - - 0.00000007591 57.0
PYH2_k127_8784538_42 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000002141 53.0
PYH2_k127_8784538_43 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000002504 56.0
PYH2_k127_8784538_5 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 459.0
PYH2_k127_8784538_6 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 423.0
PYH2_k127_8784538_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 391.0
PYH2_k127_8784538_8 Dihydroorotate dehydrogenase K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 359.0
PYH2_k127_8784538_9 SMART ATPase, AAA type, core K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 334.0
PYH2_k127_879130_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1035.0
PYH2_k127_879130_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.425e-311 971.0
PYH2_k127_879130_10 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 467.0
PYH2_k127_879130_11 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 452.0
PYH2_k127_879130_12 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 436.0
PYH2_k127_879130_13 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 422.0
PYH2_k127_879130_14 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 403.0
PYH2_k127_879130_15 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 400.0
PYH2_k127_879130_16 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 375.0
PYH2_k127_879130_17 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 351.0
PYH2_k127_879130_18 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 332.0
PYH2_k127_879130_19 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 319.0
PYH2_k127_879130_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.727e-282 900.0
PYH2_k127_879130_20 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 290.0
PYH2_k127_879130_21 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000008822 264.0
PYH2_k127_879130_22 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000002617 248.0
PYH2_k127_879130_23 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000215 235.0
PYH2_k127_879130_24 response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000001428 234.0
PYH2_k127_879130_25 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000002085 239.0
PYH2_k127_879130_26 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002904 247.0
PYH2_k127_879130_27 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000004018 238.0
PYH2_k127_879130_28 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000006276 228.0
PYH2_k127_879130_29 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000003969 221.0
PYH2_k127_879130_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 1.282e-251 811.0
PYH2_k127_879130_30 von Willebrand factor, type A K07114,K12511 - - 0.000000000000000000000000000000000000000000000102 181.0
PYH2_k127_879130_31 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000002683 183.0
PYH2_k127_879130_32 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000947 165.0
PYH2_k127_879130_33 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000001095 166.0
PYH2_k127_879130_34 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000353 158.0
PYH2_k127_879130_35 peptidase - - - 0.0000000000000000000000000000000000000488 147.0
PYH2_k127_879130_36 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000023 145.0
PYH2_k127_879130_37 IrrE N-terminal-like domain - - - 0.000000000000000000000000000000000002438 139.0
PYH2_k127_879130_38 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000239 140.0
PYH2_k127_879130_39 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000004228 141.0
PYH2_k127_879130_4 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 5.537e-235 739.0
PYH2_k127_879130_40 IrrE N-terminal-like domain - - - 0.000000000000000000000000000008252 120.0
PYH2_k127_879130_41 outer membrane efflux protein - - - 0.00000000000000000000000000001715 134.0
PYH2_k127_879130_42 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000003042 120.0
PYH2_k127_879130_43 amine dehydrogenase activity - - - 0.0000000000000000000001179 105.0
PYH2_k127_879130_44 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001725 102.0
PYH2_k127_879130_45 Domain of unknown function (DUF4411) - - - 0.0000000000000000000003197 97.0
PYH2_k127_879130_46 Sh3 type 3 domain protein K04772,K08372,K22278 - 3.5.1.104 0.0000000000000000000004013 110.0
PYH2_k127_879130_47 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000007345 82.0
PYH2_k127_879130_48 IrrE N-terminal-like domain - - - 0.0000000000009054 71.0
PYH2_k127_879130_49 Domain of unknown function (DUF4384) - - - 0.000000000002148 78.0
PYH2_k127_879130_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.459e-213 672.0
PYH2_k127_879130_50 - - - - 0.000000000004935 76.0
PYH2_k127_879130_51 - - - - 0.00000000007652 72.0
PYH2_k127_879130_52 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000001029 67.0
PYH2_k127_879130_53 secreted acid phosphatase - - - 0.000000002 63.0
PYH2_k127_879130_54 Domain of unknown function (DUF4384) - - - 0.0000002342 61.0
PYH2_k127_879130_55 - - - - 0.0002075 48.0
PYH2_k127_879130_56 LTXXQ motif family protein - - - 0.0002804 50.0
PYH2_k127_879130_6 Nickel-dependent hydrogenase - - - 4.379e-213 668.0
PYH2_k127_879130_7 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 3.982e-212 670.0
PYH2_k127_879130_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 553.0
PYH2_k127_879130_9 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 489.0
PYH2_k127_8795145_0 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 1.085e-224 704.0
PYH2_k127_8795145_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 505.0
PYH2_k127_8795145_10 membrane K08978 - - 0.00000000000000000000000000000000009778 138.0
PYH2_k127_8795145_11 spore germination - - - 0.00000000000000000000000001655 111.0
PYH2_k127_8795145_12 Cold shock protein K03704 - - 0.0000000000000000000000002814 107.0
PYH2_k127_8795145_13 - - - - 0.00000000000000000000000036 110.0
PYH2_k127_8795145_14 Protein conserved in bacteria - - - 0.00000843 57.0
PYH2_k127_8795145_15 KaiC K08482 - - 0.00001102 51.0
PYH2_k127_8795145_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 422.0
PYH2_k127_8795145_3 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005525 282.0
PYH2_k127_8795145_4 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 245.0
PYH2_k127_8795145_5 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000008826 207.0
PYH2_k127_8795145_6 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000754 175.0
PYH2_k127_8795145_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000001674 170.0
PYH2_k127_8795145_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000003279 170.0
PYH2_k127_8795145_9 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000001259 183.0
PYH2_k127_8825228_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1836.0
PYH2_k127_8825228_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.537e-317 1010.0
PYH2_k127_8825228_10 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 374.0
PYH2_k127_8825228_11 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004423 287.0
PYH2_k127_8825228_12 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000401 230.0
PYH2_k127_8825228_13 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000000000464 205.0
PYH2_k127_8825228_14 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000000003188 200.0
PYH2_k127_8825228_15 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000007543 176.0
PYH2_k127_8825228_16 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000006766 166.0
PYH2_k127_8825228_17 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000162 171.0
PYH2_k127_8825228_18 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000299 171.0
PYH2_k127_8825228_19 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000005405 147.0
PYH2_k127_8825228_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 567.0
PYH2_k127_8825228_20 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000000002243 140.0
PYH2_k127_8825228_21 ECF sigma factor - - - 0.000000000000000000000000000000001635 133.0
PYH2_k127_8825228_22 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000004748 126.0
PYH2_k127_8825228_23 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000003126 108.0
PYH2_k127_8825228_24 Thioesterase superfamily K07107 - - 0.00000000000000000000002582 105.0
PYH2_k127_8825228_25 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.00000000000000000003776 102.0
PYH2_k127_8825228_26 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000002776 91.0
PYH2_k127_8825228_27 RNA-binding S4 domain protein - - - 0.00000000000006698 75.0
PYH2_k127_8825228_28 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.0000000002234 70.0
PYH2_k127_8825228_29 ECF sigma factor - - - 0.0000000003595 63.0
PYH2_k127_8825228_3 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 518.0
PYH2_k127_8825228_30 ECF sigma factor - - - 0.00004587 46.0
PYH2_k127_8825228_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 519.0
PYH2_k127_8825228_5 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 488.0
PYH2_k127_8825228_6 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 483.0
PYH2_k127_8825228_7 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 473.0
PYH2_k127_8825228_8 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 444.0
PYH2_k127_8825228_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 432.0
PYH2_k127_8828201_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 612.0
PYH2_k127_8828201_1 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 496.0
PYH2_k127_8828201_10 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000001104 79.0
PYH2_k127_8828201_11 Uncharacterised nucleotidyltransferase - - - 0.000000000004163 78.0
PYH2_k127_8828201_12 Methyltransferase domain - - - 0.00003816 53.0
PYH2_k127_8828201_13 -O-antigen - - - 0.0005414 52.0
PYH2_k127_8828201_2 cell redox homeostasis K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 368.0
PYH2_k127_8828201_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 361.0
PYH2_k127_8828201_4 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005897 289.0
PYH2_k127_8828201_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009467 280.0
PYH2_k127_8828201_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000004895 214.0
PYH2_k127_8828201_7 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000009719 126.0
PYH2_k127_8828201_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000009207 119.0
PYH2_k127_8828201_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000004474 85.0
PYH2_k127_8886776_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 2.763e-197 621.0
PYH2_k127_8886776_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 327.0
PYH2_k127_8886776_2 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 282.0
PYH2_k127_8886776_3 Thioredoxin domain - - - 0.000000000000000000000000000000000000000004093 160.0
PYH2_k127_8886776_4 Thioredoxin domain - - - 0.0000000000000000004713 88.0
PYH2_k127_8886776_5 Glycosyl hydrolase family 26 - - - 0.000001654 57.0
PYH2_k127_8901790_0 BNR repeat-like domain K05989 - 3.2.1.40 2.788e-242 783.0
PYH2_k127_8901790_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 560.0
PYH2_k127_8901790_2 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 313.0
PYH2_k127_8901790_3 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000001237 228.0
PYH2_k127_8901790_4 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000008626 222.0
PYH2_k127_8901790_6 Belongs to the EutC family K03736 - 4.3.1.7 0.0005303 44.0
PYH2_k127_8951801_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 557.0
PYH2_k127_8951801_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 521.0
PYH2_k127_8951801_10 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 341.0
PYH2_k127_8951801_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 323.0
PYH2_k127_8951801_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002366 288.0
PYH2_k127_8951801_13 ZIP Zinc transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000001223 221.0
PYH2_k127_8951801_14 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000001211 166.0
PYH2_k127_8951801_15 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000898 51.0
PYH2_k127_8951801_16 Cell division protein FtsQ K03589 - - 0.0004386 52.0
PYH2_k127_8951801_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 464.0
PYH2_k127_8951801_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 436.0
PYH2_k127_8951801_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 437.0
PYH2_k127_8951801_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 425.0
PYH2_k127_8951801_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 428.0
PYH2_k127_8951801_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 394.0
PYH2_k127_8951801_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 353.0
PYH2_k127_8951801_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 358.0
PYH2_k127_8968938_0 Fibronectin type III-like domain K05349 - 3.2.1.21 4.917e-281 887.0
PYH2_k127_8968938_1 PFAM Amidase - - - 3.097e-271 845.0
PYH2_k127_8968938_10 region 4 type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008286 270.0
PYH2_k127_8968938_11 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001097 278.0
PYH2_k127_8968938_12 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004241 280.0
PYH2_k127_8968938_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001537 245.0
PYH2_k127_8968938_14 ABC-type molybdate transport system, ATPase component K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000002523 250.0
PYH2_k127_8968938_15 Alpha/beta hydrolase family K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000003474 243.0
PYH2_k127_8968938_16 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000008675 237.0
PYH2_k127_8968938_17 Protein of unknown function (DUF3616) - - - 0.00000000000000000000000000000000000000000000000000000000002001 221.0
PYH2_k127_8968938_18 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000007335 220.0
PYH2_k127_8968938_19 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000008346 204.0
PYH2_k127_8968938_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 6.46e-239 752.0
PYH2_k127_8968938_20 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000001133 197.0
PYH2_k127_8968938_21 hydrolase of the alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000000474 201.0
PYH2_k127_8968938_22 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000003164 182.0
PYH2_k127_8968938_23 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000003949 149.0
PYH2_k127_8968938_24 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000005317 149.0
PYH2_k127_8968938_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000001081 143.0
PYH2_k127_8968938_26 PFAM Phosphoglycerate mutase K08296 - - 0.00000000000000000000000000000000001411 142.0
PYH2_k127_8968938_27 Cytidylate kinase-like family K00760 - 2.4.2.8 0.00000000000000000000000000000000003829 144.0
PYH2_k127_8968938_28 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000001383 116.0
PYH2_k127_8968938_29 nucleotide catabolic process - - - 0.00000000000000000000002023 114.0
PYH2_k127_8968938_3 PFAM AMP-dependent synthetase and ligase K00666 - - 1.445e-217 688.0
PYH2_k127_8968938_30 iron ion homeostasis - - - 0.000000000000000000001083 108.0
PYH2_k127_8968938_31 beta-propeller repeat - - - 0.0000000000000000002129 90.0
PYH2_k127_8968938_32 COG1064 Zn-dependent alcohol K13979 - - 0.00000000000000001312 88.0
PYH2_k127_8968938_33 - - - - 0.00000000000000006177 87.0
PYH2_k127_8968938_34 YacP-like NYN domain - - - 0.0000000000000005093 84.0
PYH2_k127_8968938_35 Domain of unknown function (DUF4956) - - - 0.0000005641 61.0
PYH2_k127_8968938_36 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0003641 43.0
PYH2_k127_8968938_4 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 587.0
PYH2_k127_8968938_5 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 436.0
PYH2_k127_8968938_6 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 435.0
PYH2_k127_8968938_7 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 402.0
PYH2_k127_8968938_8 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 309.0
PYH2_k127_896953_0 Beta-lactamase - - - 4.526e-255 808.0
PYH2_k127_896953_1 efflux transmembrane transporter activity - - - 1.088e-216 699.0
PYH2_k127_896953_10 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 363.0
PYH2_k127_896953_11 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 325.0
PYH2_k127_896953_12 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 290.0
PYH2_k127_896953_13 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
PYH2_k127_896953_14 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
PYH2_k127_896953_15 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000004253 177.0
PYH2_k127_896953_16 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000007546 169.0
PYH2_k127_896953_17 - - - - 0.0000000000000000000000000000000000008742 141.0
PYH2_k127_896953_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000682 144.0
PYH2_k127_896953_19 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000475 105.0
PYH2_k127_896953_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.554e-216 690.0
PYH2_k127_896953_20 - - - - 0.00000000000000000000009151 99.0
PYH2_k127_896953_21 mRNA binding K07339 - - 0.0000000000000000000002405 99.0
PYH2_k127_896953_22 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000003186 96.0
PYH2_k127_896953_23 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000003519 97.0
PYH2_k127_896953_24 PDZ DHR GLGF domain protein - - - 0.000000000000000000002745 106.0
PYH2_k127_896953_25 - - - - 0.0000000000000000000722 90.0
PYH2_k127_896953_26 - - - - 0.000000000000000001559 88.0
PYH2_k127_896953_27 ORF located using Blastx - - - 0.000000000000001825 77.0
PYH2_k127_896953_28 - - - - 0.0000000000001302 81.0
PYH2_k127_896953_29 - - - - 0.0000000000005997 70.0
PYH2_k127_896953_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.184e-212 676.0
PYH2_k127_896953_30 - - - - 0.000000000005295 67.0
PYH2_k127_896953_32 - - - - 0.00000000008953 62.0
PYH2_k127_896953_33 - - - - 0.0000000001699 62.0
PYH2_k127_896953_34 - - - - 0.0000000001979 62.0
PYH2_k127_896953_35 - - - - 0.0000000008801 60.0
PYH2_k127_896953_36 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000001207 66.0
PYH2_k127_896953_37 - - - - 0.00000007305 55.0
PYH2_k127_896953_39 - - - - 0.0000001848 56.0
PYH2_k127_896953_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 563.0
PYH2_k127_896953_40 Domain of unknown function (DUF1508) K09946 - - 0.0000003269 53.0
PYH2_k127_896953_42 Putative adhesin - - - 0.00001172 57.0
PYH2_k127_896953_5 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 435.0
PYH2_k127_896953_6 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 387.0
PYH2_k127_896953_7 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 398.0
PYH2_k127_896953_8 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 385.0
PYH2_k127_896953_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 364.0
PYH2_k127_8986281_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.479e-235 735.0
PYH2_k127_8986281_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 578.0
PYH2_k127_8986281_10 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000000000000000000000000000000000001681 196.0
PYH2_k127_8986281_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000001887 197.0
PYH2_k127_8986281_12 PFAM Response regulator receiver domain K02483,K18344 - - 0.00000000000000000000000000000000000000000000000000002128 198.0
PYH2_k127_8986281_13 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000001437 191.0
PYH2_k127_8986281_14 PIN domain - - - 0.00000000000000000000000000000000000000000000004966 172.0
PYH2_k127_8986281_15 nuclease of the RecB family - - - 0.00000000000000000000000000000000000000000000006189 183.0
PYH2_k127_8986281_16 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000128 171.0
PYH2_k127_8986281_17 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000000000000000000007274 168.0
PYH2_k127_8986281_18 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000204 157.0
PYH2_k127_8986281_19 Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000001976 151.0
PYH2_k127_8986281_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 542.0
PYH2_k127_8986281_20 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000001948 138.0
PYH2_k127_8986281_21 - - - - 0.0000000000000000000000000009166 115.0
PYH2_k127_8986281_22 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000013 129.0
PYH2_k127_8986281_23 - - - - 0.00000000000000000000000002893 112.0
PYH2_k127_8986281_24 Rubrerythrin - - - 0.0000000000000000000000006354 110.0
PYH2_k127_8986281_25 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000000921 111.0
PYH2_k127_8986281_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000002097 107.0
PYH2_k127_8986281_27 MarR family transcriptional regulator - - - 0.00000000000000000001709 92.0
PYH2_k127_8986281_28 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000000000006273 100.0
PYH2_k127_8986281_29 - - - - 0.0000000000000000005736 89.0
PYH2_k127_8986281_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 486.0
PYH2_k127_8986281_30 protein conserved in cyanobacteria - - - 0.0000000000000000008349 94.0
PYH2_k127_8986281_31 - - - - 0.0000000000000002453 83.0
PYH2_k127_8986281_32 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000005078 79.0
PYH2_k127_8986281_33 DNA binding domain with preference for A/T rich regions - - - 0.0000000000000008401 85.0
PYH2_k127_8986281_34 - - - - 0.00000000000006977 73.0
PYH2_k127_8986281_35 InterPro IPR007367 - - - 0.000000000002951 72.0
PYH2_k127_8986281_36 Amidohydrolase family K01468 - 3.5.2.7 0.0000000438 57.0
PYH2_k127_8986281_37 Protein of unknown function (DUF2662) - - - 0.0000001913 62.0
PYH2_k127_8986281_38 Protein of unknown function (DUF2442) - - - 0.0000005795 59.0
PYH2_k127_8986281_39 serine-type peptidase activity - - - 0.000001973 53.0
PYH2_k127_8986281_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 323.0
PYH2_k127_8986281_40 Cellulose synthase subunit BcsC K20543 - - 0.0005747 53.0
PYH2_k127_8986281_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
PYH2_k127_8986281_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 302.0
PYH2_k127_8986281_7 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000392 221.0
PYH2_k127_8986281_8 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000004057 210.0
PYH2_k127_8986281_9 - - - - 0.000000000000000000000000000000000000000000000000000000005889 211.0
PYH2_k127_9002922_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.5e-307 948.0
PYH2_k127_9002922_1 AAA domain - - - 1.06e-306 960.0
PYH2_k127_9002922_10 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 514.0
PYH2_k127_9002922_11 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 517.0
PYH2_k127_9002922_12 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 503.0
PYH2_k127_9002922_13 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 473.0
PYH2_k127_9002922_14 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 445.0
PYH2_k127_9002922_15 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 412.0
PYH2_k127_9002922_16 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 372.0
PYH2_k127_9002922_17 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 328.0
PYH2_k127_9002922_18 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 322.0
PYH2_k127_9002922_19 Highly conserved protein containing a thioredoxin domain K20948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 324.0
PYH2_k127_9002922_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.029e-241 754.0
PYH2_k127_9002922_20 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 313.0
PYH2_k127_9002922_21 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 303.0
PYH2_k127_9002922_22 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006289 275.0
PYH2_k127_9002922_23 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009312 268.0
PYH2_k127_9002922_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007483 271.0
PYH2_k127_9002922_26 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000005607 205.0
PYH2_k127_9002922_27 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000008125 203.0
PYH2_k127_9002922_28 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000006125 190.0
PYH2_k127_9002922_29 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000001623 183.0
PYH2_k127_9002922_3 Phosphate acyltransferases K01897 - 6.2.1.3 2.495e-236 765.0
PYH2_k127_9002922_30 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000002709 184.0
PYH2_k127_9002922_31 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms - - - 0.000000000000000000000000000000000000000000000004668 178.0
PYH2_k127_9002922_32 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000002139 138.0
PYH2_k127_9002922_33 Ion channel - - - 0.00000000000000000000000000000002846 130.0
PYH2_k127_9002922_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000001574 126.0
PYH2_k127_9002922_35 metallopeptidase activity - - - 0.0000000000000000000000000000707 125.0
PYH2_k127_9002922_36 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000002291 120.0
PYH2_k127_9002922_37 AMP binding - - - 0.000000000000000000000014 111.0
PYH2_k127_9002922_38 Thiamine-binding protein - - - 0.00000000000000000000002166 103.0
PYH2_k127_9002922_39 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000000000005409 101.0
PYH2_k127_9002922_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.288e-224 705.0
PYH2_k127_9002922_40 AMP binding - - - 0.000000000000000000003744 100.0
PYH2_k127_9002922_41 Universal stress protein - - - 0.000000000000000000106 96.0
PYH2_k127_9002922_42 AMP binding K06149 - - 0.000000000000000001107 96.0
PYH2_k127_9002922_43 MacB-like periplasmic core domain K02004 - - 0.000000000000000004474 85.0
PYH2_k127_9002922_44 Disulphide bond corrector protein DsbC K04084,K06888 - 1.8.1.8 0.000000000000000009754 89.0
PYH2_k127_9002922_46 Universal stress protein family - - - 0.000000000000001478 87.0
PYH2_k127_9002922_47 Universal stress protein family - - - 0.00000000000003722 83.0
PYH2_k127_9002922_48 Protein conserved in bacteria K09778 - - 0.0000000000002955 81.0
PYH2_k127_9002922_49 BON domain K04065 - - 0.0000000000006192 74.0
PYH2_k127_9002922_5 Zinc-binding dehydrogenase - - - 4.46e-217 695.0
PYH2_k127_9002922_51 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00004721 48.0
PYH2_k127_9002922_6 Amidase K01426 - 3.5.1.4 9.711e-210 665.0
PYH2_k127_9002922_7 (ABC) transporter K06147,K06148 - - 2.87e-205 660.0
PYH2_k127_9002922_8 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 595.0
PYH2_k127_9002922_9 Sodium/calcium exchanger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 577.0
PYH2_k127_9010770_0 SMART Elongator protein 3 MiaB NifB - - - 3.963e-222 722.0
PYH2_k127_9010770_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 522.0
PYH2_k127_9010770_10 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000001552 106.0
PYH2_k127_9010770_11 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000006051 94.0
PYH2_k127_9010770_12 shape-determining protein MreD K03571 - - 0.000000000002407 74.0
PYH2_k127_9010770_13 beta-fructofuranosidase activity - - - 0.0000004257 52.0
PYH2_k127_9010770_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 494.0
PYH2_k127_9010770_3 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 394.0
PYH2_k127_9010770_4 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 299.0
PYH2_k127_9010770_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000001954 246.0
PYH2_k127_9010770_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000004379 185.0
PYH2_k127_9010770_7 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000789 202.0
PYH2_k127_9010770_8 GAF domain - - - 0.000000000000000000000000000000000000000000003262 177.0
PYH2_k127_9010770_9 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000007599 162.0
PYH2_k127_9041497_0 Prokaryotic cytochrome b561 - - - 2.336e-235 745.0
PYH2_k127_9041497_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.777e-215 702.0
PYH2_k127_9041497_10 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000001938 193.0
PYH2_k127_9041497_11 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000000001684 180.0
PYH2_k127_9041497_12 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000000000000000000007444 175.0
PYH2_k127_9041497_13 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000523 170.0
PYH2_k127_9041497_14 Alpha beta K06889 - - 0.00000000000000000000000000000005871 137.0
PYH2_k127_9041497_15 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000001257 101.0
PYH2_k127_9041497_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000001762 81.0
PYH2_k127_9041497_17 PFAM Tetratricopeptide repeat - - - 0.000000000002148 79.0
PYH2_k127_9041497_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00009942 49.0
PYH2_k127_9041497_19 heat shock protein binding - - - 0.0006611 48.0
PYH2_k127_9041497_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 491.0
PYH2_k127_9041497_3 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 408.0
PYH2_k127_9041497_4 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 393.0
PYH2_k127_9041497_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 294.0
PYH2_k127_9041497_6 PFAM type I phosphodiesterase nucleotide pyrophosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001055 290.0
PYH2_k127_9041497_7 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000002166 239.0
PYH2_k127_9041497_8 - - - - 0.00000000000000000000000000000000000000000000000000000000188 224.0
PYH2_k127_9041497_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000009453 192.0
PYH2_k127_9089243_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1259.0
PYH2_k127_9089243_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.197e-204 657.0
PYH2_k127_9089243_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000002932 205.0
PYH2_k127_9089243_11 recA bacterial DNA recombination protein - - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
PYH2_k127_9089243_12 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000009172 198.0
PYH2_k127_9089243_13 EVE domain - - - 0.0000000000000000000000000000000000000000000000005967 179.0
PYH2_k127_9089243_14 DinB family - - - 0.000000000000000000000000000000000000000000007698 168.0
PYH2_k127_9089243_15 - - - - 0.00000000000000000000000000000000000000001644 160.0
PYH2_k127_9089243_16 Protein of unknown function DUF84 - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.00000000000000000000000000006603 124.0
PYH2_k127_9089243_17 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000006039 111.0
PYH2_k127_9089243_18 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000004061 97.0
PYH2_k127_9089243_19 sequence-specific DNA binding K07726 - - 0.00000000000000001612 86.0
PYH2_k127_9089243_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 471.0
PYH2_k127_9089243_20 DinB family - - - 0.000000000008074 72.0
PYH2_k127_9089243_21 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000001153 63.0
PYH2_k127_9089243_22 Ftsk_gamma K03466 - - 0.00004539 53.0
PYH2_k127_9089243_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 374.0
PYH2_k127_9089243_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 344.0
PYH2_k127_9089243_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 316.0
PYH2_k127_9089243_6 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000996 272.0
PYH2_k127_9089243_7 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003379 276.0
PYH2_k127_9089243_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000004472 252.0
PYH2_k127_9089243_9 dna methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003533 247.0
PYH2_k127_9091722_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 624.0
PYH2_k127_9091722_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 460.0
PYH2_k127_9091722_10 AntiSigma factor - - - 0.00000003111 63.0
PYH2_k127_9091722_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
PYH2_k127_9091722_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000006206 213.0
PYH2_k127_9091722_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000001456 181.0
PYH2_k127_9091722_5 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000009779 170.0
PYH2_k127_9091722_6 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000004263 152.0
PYH2_k127_9091722_7 phosphorelay signal transduction system K02488,K04757 - 2.7.11.1,2.7.7.65 0.00000000000000000000000002675 115.0
PYH2_k127_9091722_8 - - - - 0.00000000000001066 76.0
PYH2_k127_9091722_9 - - - - 0.00000000006302 72.0
PYH2_k127_9119084_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.002e-235 745.0
PYH2_k127_9119084_1 B12 binding domain - - - 5.578e-228 719.0
PYH2_k127_9119084_10 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 465.0
PYH2_k127_9119084_11 glycogen (starch) synthase activity K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 449.0
PYH2_k127_9119084_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 409.0
PYH2_k127_9119084_13 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 336.0
PYH2_k127_9119084_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
PYH2_k127_9119084_15 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
PYH2_k127_9119084_16 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
PYH2_k127_9119084_17 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 288.0
PYH2_k127_9119084_18 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001932 267.0
PYH2_k127_9119084_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006778 265.0
PYH2_k127_9119084_2 Amidase K01426 - 3.5.1.4 2.255e-227 718.0
PYH2_k127_9119084_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005387 263.0
PYH2_k127_9119084_21 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000004658 233.0
PYH2_k127_9119084_22 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
PYH2_k127_9119084_23 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000007956 239.0
PYH2_k127_9119084_24 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000003173 220.0
PYH2_k127_9119084_25 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000009432 216.0
PYH2_k127_9119084_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000004284 213.0
PYH2_k127_9119084_27 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000001828 214.0
PYH2_k127_9119084_28 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000434 194.0
PYH2_k127_9119084_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000001042 194.0
PYH2_k127_9119084_3 Transcriptional regulator K06921 - - 2.298e-226 732.0
PYH2_k127_9119084_30 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000004417 190.0
PYH2_k127_9119084_31 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000009876 186.0
PYH2_k127_9119084_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000003183 179.0
PYH2_k127_9119084_33 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000007418 165.0
PYH2_k127_9119084_34 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000001381 164.0
PYH2_k127_9119084_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000003394 149.0
PYH2_k127_9119084_36 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000004508 147.0
PYH2_k127_9119084_37 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000001617 143.0
PYH2_k127_9119084_38 - - - - 0.0000000000000000000000000000000001078 137.0
PYH2_k127_9119084_39 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000001207 137.0
PYH2_k127_9119084_4 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 596.0
PYH2_k127_9119084_40 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000003237 132.0
PYH2_k127_9119084_41 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000009319 131.0
PYH2_k127_9119084_42 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000005531 130.0
PYH2_k127_9119084_43 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000001119 123.0
PYH2_k127_9119084_44 addiction module antidote protein HigA - - - 0.000000000000000000000000002595 113.0
PYH2_k127_9119084_45 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000728 104.0
PYH2_k127_9119084_46 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000005921 101.0
PYH2_k127_9119084_47 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001096 93.0
PYH2_k127_9119084_48 Ribosomal protein L30 K02907 - - 0.00000000000000002124 83.0
PYH2_k127_9119084_49 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000077 80.0
PYH2_k127_9119084_5 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 587.0
PYH2_k127_9119084_50 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000006068 75.0
PYH2_k127_9119084_51 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000006149 79.0
PYH2_k127_9119084_52 DinB superfamily - - - 0.00000000000002011 75.0
PYH2_k127_9119084_53 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000002172 72.0
PYH2_k127_9119084_55 Ribosomal L29 protein K02904 - - 0.00000000001283 68.0
PYH2_k127_9119084_56 IMG reference gene - - - 0.00000000001885 74.0
PYH2_k127_9119084_57 self proteolysis - - - 0.00000000003171 72.0
PYH2_k127_9119084_58 Putative zinc- or iron-chelating domain K06940 - - 0.0000417 51.0
PYH2_k127_9119084_59 Protein of unknown function (DUF1573) - - - 0.00004708 49.0
PYH2_k127_9119084_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 507.0
PYH2_k127_9119084_7 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 501.0
PYH2_k127_9119084_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 481.0
PYH2_k127_9119084_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 475.0
PYH2_k127_9162508_0 Baseplate J-like protein - - - 0.0 1224.0
PYH2_k127_9162508_1 Protein of unknown function (DUF1553) - - - 0.0 1203.0
PYH2_k127_9162508_10 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 575.0
PYH2_k127_9162508_11 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 564.0
PYH2_k127_9162508_12 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 572.0
PYH2_k127_9162508_13 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 580.0
PYH2_k127_9162508_14 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 542.0
PYH2_k127_9162508_15 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 527.0
PYH2_k127_9162508_16 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 523.0
PYH2_k127_9162508_17 Phage tail sheath C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 510.0
PYH2_k127_9162508_18 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 511.0
PYH2_k127_9162508_19 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 491.0
PYH2_k127_9162508_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 7.023e-276 862.0
PYH2_k127_9162508_20 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
PYH2_k127_9162508_21 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 443.0
PYH2_k127_9162508_22 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 427.0
PYH2_k127_9162508_23 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 423.0
PYH2_k127_9162508_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 376.0
PYH2_k127_9162508_25 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 346.0
PYH2_k127_9162508_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 344.0
PYH2_k127_9162508_27 Peptidase M36 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 347.0
PYH2_k127_9162508_28 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 321.0
PYH2_k127_9162508_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 311.0
PYH2_k127_9162508_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.329e-269 840.0
PYH2_k127_9162508_30 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 321.0
PYH2_k127_9162508_31 PFAM YdjC family protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
PYH2_k127_9162508_32 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 296.0
PYH2_k127_9162508_33 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001795 282.0
PYH2_k127_9162508_34 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005628 271.0
PYH2_k127_9162508_35 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 266.0
PYH2_k127_9162508_36 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 252.0
PYH2_k127_9162508_37 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006289 264.0
PYH2_k127_9162508_38 domain, Protein K15125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001712 252.0
PYH2_k127_9162508_39 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
PYH2_k127_9162508_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.259e-263 825.0
PYH2_k127_9162508_40 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000001077 211.0
PYH2_k127_9162508_42 - - - - 0.000000000000000000000000000000000000000000000000000001722 194.0
PYH2_k127_9162508_43 Rhs element vgr protein - - - 0.0000000000000000000000000000000000000000000000000000738 194.0
PYH2_k127_9162508_44 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000008127 197.0
PYH2_k127_9162508_46 - - - - 0.0000000000000000000000000000000000000000000000002596 183.0
PYH2_k127_9162508_47 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000005346 181.0
PYH2_k127_9162508_48 - - - - 0.0000000000000000000000000000000000000000000000005483 181.0
PYH2_k127_9162508_49 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000008295 167.0
PYH2_k127_9162508_5 Protein of unknown function (DUF1501) - - - 1.157e-253 793.0
PYH2_k127_9162508_50 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000001459 179.0
PYH2_k127_9162508_51 PAAR motif - - - 0.000000000000000000000000000000000000002311 151.0
PYH2_k127_9162508_52 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000001994 130.0
PYH2_k127_9162508_53 cheY-homologous receiver domain - - - 0.00000000000000000000000000001524 124.0
PYH2_k127_9162508_54 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000001367 118.0
PYH2_k127_9162508_55 - - - - 0.000000000000000001035 88.0
PYH2_k127_9162508_56 Domain of unknown function (DUF4157) - - - 0.000000000000000001097 101.0
PYH2_k127_9162508_57 - - - - 0.000000000000000004437 84.0
PYH2_k127_9162508_58 - - - - 0.0000000000000000603 87.0
PYH2_k127_9162508_6 Phage tail protein (Tail_P2_I) - - - 3.14e-253 800.0
PYH2_k127_9162508_60 Domain of unknown function (DUF4157) - - - 0.0000000000000009192 91.0
PYH2_k127_9162508_61 - - - - 0.0000000000000009978 77.0
PYH2_k127_9162508_62 - - - - 0.00000000001145 78.0
PYH2_k127_9162508_63 Glucose-methanol-choline (GMC) oxidoreductase NAD binding site - - - 0.00000000002528 64.0
PYH2_k127_9162508_65 Evidence 4 Homologs of previously reported genes of - - - 0.0000344 48.0
PYH2_k127_9162508_66 HEAT repeats - - - 0.00007258 52.0
PYH2_k127_9162508_67 PIN domain - - - 0.0004132 44.0
PYH2_k127_9162508_7 Prolyl oligopeptidase family - - - 1.086e-244 775.0
PYH2_k127_9162508_8 Baseplate J-like protein - - - 1.058e-229 733.0
PYH2_k127_9162508_9 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 2.351e-199 626.0
PYH2_k127_9169199_0 Protein of unknown function (DUF1553) - - - 0.0 1110.0
PYH2_k127_9169199_1 Protein of unknown function (DUF1501) - - - 1.055e-234 733.0
PYH2_k127_9169199_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 302.0
PYH2_k127_9169199_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000003418 229.0
PYH2_k127_9169199_4 - - - - 0.000004393 57.0
PYH2_k127_9192892_0 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 349.0
PYH2_k127_9192892_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000008037 164.0
PYH2_k127_9192892_2 SLBB domain K01991 - - 0.00000000000000000000000000001188 132.0
PYH2_k127_9192892_3 Tetratricopeptide repeat - - - 0.000000000000001777 89.0
PYH2_k127_9204223_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 5.655e-197 628.0
PYH2_k127_9204223_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 487.0
PYH2_k127_9204223_10 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000003562 111.0
PYH2_k127_9204223_11 DUF167 K09131 - - 0.000000000000000000000008439 103.0
PYH2_k127_9204223_12 PFAM heat shock protein DnaJ domain protein K05516 - - 0.00000000000000006195 90.0
PYH2_k127_9204223_13 - - - - 0.0000000000000000916 83.0
PYH2_k127_9204223_14 energy transducer activity K02487,K03832,K06596 - - 0.000000000001798 78.0
PYH2_k127_9204223_15 DnaJ (Hsp40) homolog, subfamily C, member 11 K09531 GO:0001671,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008047,GO:0008104,GO:0008150,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0017038,GO:0019867,GO:0030150,GO:0030234,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032781,GO:0033036,GO:0033365,GO:0034613,GO:0042407,GO:0042886,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044093,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051336,GO:0051345,GO:0051641,GO:0051649,GO:0055085,GO:0060589,GO:0060590,GO:0061024,GO:0065002,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0098588,GO:0098772,GO:0098805,GO:1990542 - 0.000000007366 68.0
PYH2_k127_9204223_16 Putative restriction endonuclease - - - 0.000007294 54.0
PYH2_k127_9204223_17 integral membrane protein K02221 - - 0.0001352 52.0
PYH2_k127_9204223_2 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 432.0
PYH2_k127_9204223_3 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 317.0
PYH2_k127_9204223_4 Domain of unknown function (DUF3471) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003452 274.0
PYH2_k127_9204223_5 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005748 251.0
PYH2_k127_9204223_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000004153 237.0
PYH2_k127_9204223_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000008537 214.0
PYH2_k127_9204223_8 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000004911 194.0
PYH2_k127_9204223_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000003184 174.0
PYH2_k127_9225613_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 399.0
PYH2_k127_9225613_1 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 314.0
PYH2_k127_946942_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1246.0
PYH2_k127_946942_1 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.886e-241 755.0
PYH2_k127_946942_2 metallocarboxypeptidase activity K14054 - - 2.202e-198 633.0
PYH2_k127_946942_3 Belongs to the glycosyl hydrolase family 6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 516.0
PYH2_k127_946942_4 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007286 260.0
PYH2_k127_946942_5 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001038 250.0
PYH2_k127_946942_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000002169 211.0
PYH2_k127_946942_7 - - - - 0.00000000000000000000000000000000000000000000000158 181.0
PYH2_k127_946942_8 - - - - 0.0000000000000000000000000000000000000000000003024 175.0
PYH2_k127_978408_0 CHASE3 domain - - - 5.668e-249 791.0
PYH2_k127_978408_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 442.0
PYH2_k127_978408_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000009215 172.0
PYH2_k127_978408_11 protein containing caspase domain - - - 0.00000000000000000000000000000000004783 155.0
PYH2_k127_978408_12 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.00000000000000000000000000000009505 146.0
PYH2_k127_978408_13 AMP binding K06149 - - 0.0000000000000000000000000002656 122.0
PYH2_k127_978408_14 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000001548 100.0
PYH2_k127_978408_15 FtsX-like permease family - - - 0.00000000000000001369 85.0
PYH2_k127_978408_16 Transposase IS200 like - - - 0.00000000000000002976 90.0
PYH2_k127_978408_17 TIGRFAM conserved repeat domain - - - 0.00000000000000003513 98.0
PYH2_k127_978408_18 MacB-like periplasmic core domain - - - 0.000000000005084 68.0
PYH2_k127_978408_19 Beta-lactamase - - - 0.0000000002854 69.0
PYH2_k127_978408_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 356.0
PYH2_k127_978408_20 - - - - 0.00009035 57.0
PYH2_k127_978408_3 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 325.0
PYH2_k127_978408_4 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 308.0
PYH2_k127_978408_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000842 287.0
PYH2_k127_978408_6 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001586 274.0
PYH2_k127_978408_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000001244 239.0
PYH2_k127_978408_8 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000002457 187.0
PYH2_k127_978408_9 thiolester hydrolase activity K07000 - - 0.00000000000000000000000000000000000000000000002197 182.0
PYH2_k127_992737_0 Tricorn protease PDZ domain K08676 - - 2.713e-237 771.0
PYH2_k127_992737_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 499.0
PYH2_k127_992737_10 MacB-like periplasmic core domain - - - 0.0000000007819 62.0
PYH2_k127_992737_11 MacB-like periplasmic core domain - - - 0.00000004236 59.0
PYH2_k127_992737_12 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000003244 56.0
PYH2_k127_992737_2 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 396.0
PYH2_k127_992737_3 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 334.0
PYH2_k127_992737_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 311.0
PYH2_k127_992737_5 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000001844 209.0
PYH2_k127_992737_6 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000004668 191.0
PYH2_k127_992737_7 chlorophyll binding - - - 0.000000000000000000000000000000000779 144.0
PYH2_k127_992737_8 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000449 130.0
PYH2_k127_992737_9 Putative adhesin - - - 0.00000000000000000000000000008481 126.0
PYH2_k127_996258_0 cellulose binding - - - 0.0 1394.0
PYH2_k127_996258_1 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.384e-261 822.0
PYH2_k127_996258_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
PYH2_k127_996258_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003381 264.0
PYH2_k127_996258_12 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000785 238.0
PYH2_k127_996258_13 WD40 repeat, subgroup - - - 0.000000000000000000000000000000000000000000000000000001522 218.0
PYH2_k127_996258_14 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000004586 155.0
PYH2_k127_996258_15 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000001002 141.0
PYH2_k127_996258_16 BMC - - - 0.0000000000000000000000000000000001836 134.0
PYH2_k127_996258_17 Thioesterase superfamily - - - 0.0000000000000000000000000003984 121.0
PYH2_k127_996258_18 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000009619 112.0
PYH2_k127_996258_19 methyltransferase K02169 - 2.1.1.197 0.00000000000000000000000002839 118.0
PYH2_k127_996258_2 Amidohydrolase family - - - 2.985e-225 704.0
PYH2_k127_996258_20 - - - - 0.000000000000000000000001566 106.0
PYH2_k127_996258_21 - - - - 0.00000000000004522 79.0
PYH2_k127_996258_22 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000001934 67.0
PYH2_k127_996258_23 Sh3 type 3 domain protein - - - 0.0000003954 62.0
PYH2_k127_996258_25 Fic/DOC family - - - 0.0007791 50.0
PYH2_k127_996258_3 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 1.68e-214 678.0
PYH2_k127_996258_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.612e-202 645.0
PYH2_k127_996258_5 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 541.0
PYH2_k127_996258_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 488.0
PYH2_k127_996258_7 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 421.0
PYH2_k127_996258_8 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
PYH2_k127_996258_9 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0