Overview

ID MAG03183
Name PYH2_bin.26
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus 2-02-FULL-62-14
Species
Assembly information
Completeness (%) 88.11
Contamination (%) 3.52
GC content (%) 63.0
N50 (bp) 18,889
Genome size (bp) 2,347,568

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2101

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1000518_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 525.0
PYH2_k127_1000518_1 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 374.0
PYH2_k127_1003351_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1339.0
PYH2_k127_1003351_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1326.0
PYH2_k127_1003351_10 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 441.0
PYH2_k127_1003351_11 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 411.0
PYH2_k127_1003351_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 379.0
PYH2_k127_1003351_13 PFAM RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 359.0
PYH2_k127_1003351_14 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 356.0
PYH2_k127_1003351_15 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
PYH2_k127_1003351_16 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 310.0
PYH2_k127_1003351_17 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
PYH2_k127_1003351_18 Alpha/beta hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 303.0
PYH2_k127_1003351_19 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001118 267.0
PYH2_k127_1003351_2 ABC transporter K06020 - 3.6.3.25 2e-315 970.0
PYH2_k127_1003351_20 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
PYH2_k127_1003351_21 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005509 257.0
PYH2_k127_1003351_23 Evidence 4 Homologs of previously reported genes of K15977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007388 244.0
PYH2_k127_1003351_24 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008106 242.0
PYH2_k127_1003351_25 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001011 231.0
PYH2_k127_1003351_27 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000001274 209.0
PYH2_k127_1003351_28 MEKHLA domain - - - 0.0000000000000000000000000000000000000000000000000000000003143 205.0
PYH2_k127_1003351_29 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000000000000000000000001649 199.0
PYH2_k127_1003351_3 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 6.874e-252 785.0
PYH2_k127_1003351_30 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000006634 216.0
PYH2_k127_1003351_31 Protein conserved in bacteria K16785 - - 0.0000000000000000000000000000000000000000000000000002141 188.0
PYH2_k127_1003351_33 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000001679 175.0
PYH2_k127_1003351_34 - - - - 0.000000000000000000000000000000000000000000003347 181.0
PYH2_k127_1003351_35 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.00000000000000000000000000000000000000001472 154.0
PYH2_k127_1003351_36 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000000000000000002676 143.0
PYH2_k127_1003351_38 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000003171 130.0
PYH2_k127_1003351_39 Belongs to the ompA family K03640 - - 0.00000000000000000000000000001742 124.0
PYH2_k127_1003351_4 Aminotransferase class I and II K10206 - 2.6.1.83 6.018e-220 685.0
PYH2_k127_1003351_42 Polymer-forming cytoskeletal - - - 0.00000000000000000000000001507 115.0
PYH2_k127_1003351_43 Protein of unknown function (DUF1653) - - - 0.0000000000000000000000001235 108.0
PYH2_k127_1003351_44 - - - - 0.0000000000000000000000005575 112.0
PYH2_k127_1003351_49 Polymer-forming cytoskeletal - - - 0.00000000000004407 78.0
PYH2_k127_1003351_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.84e-212 667.0
PYH2_k127_1003351_50 Ribosomal protein L7/L12 C-terminal domain - - - 0.000000001363 64.0
PYH2_k127_1003351_52 Protein involved in outer membrane biogenesis - - - 0.0000002204 58.0
PYH2_k127_1003351_53 - - - - 0.000174 53.0
PYH2_k127_1003351_6 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 587.0
PYH2_k127_1003351_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 568.0
PYH2_k127_1003351_8 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 531.0
PYH2_k127_1003351_9 Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 528.0
PYH2_k127_1036173_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 7.529e-258 798.0
PYH2_k127_1036173_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.129e-223 697.0
PYH2_k127_1036173_10 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 473.0
PYH2_k127_1036173_11 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 443.0
PYH2_k127_1036173_12 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 438.0
PYH2_k127_1036173_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 415.0
PYH2_k127_1036173_14 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 399.0
PYH2_k127_1036173_15 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 406.0
PYH2_k127_1036173_16 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 347.0
PYH2_k127_1036173_17 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 336.0
PYH2_k127_1036173_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 333.0
PYH2_k127_1036173_19 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002248 284.0
PYH2_k127_1036173_2 Putative modulator of DNA gyrase K03568 - - 4.729e-207 656.0
PYH2_k127_1036173_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000008893 251.0
PYH2_k127_1036173_21 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000204 245.0
PYH2_k127_1036173_22 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000001207 228.0
PYH2_k127_1036173_23 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000001458 232.0
PYH2_k127_1036173_24 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003045 220.0
PYH2_k127_1036173_25 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000000000000002671 220.0
PYH2_k127_1036173_26 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
PYH2_k127_1036173_28 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000002714 144.0
PYH2_k127_1036173_29 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000001197 136.0
PYH2_k127_1036173_3 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 572.0
PYH2_k127_1036173_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000001322 115.0
PYH2_k127_1036173_32 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008823 96.0
PYH2_k127_1036173_33 zinc-ribbon domain - - - 0.00000000000000000002953 96.0
PYH2_k127_1036173_34 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000007607 81.0
PYH2_k127_1036173_35 Domain of unknown function (DUF4864) - - - 0.000000000005232 70.0
PYH2_k127_1036173_36 Putative modulator of DNA gyrase K03568 - - 0.00000003294 55.0
PYH2_k127_1036173_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 567.0
PYH2_k127_1036173_5 metallopeptidase activity K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 558.0
PYH2_k127_1036173_6 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 529.0
PYH2_k127_1036173_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 507.0
PYH2_k127_1036173_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 482.0
PYH2_k127_1036173_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 476.0
PYH2_k127_1039317_0 amine dehydrogenase activity - - - 0.0 1630.0
PYH2_k127_1039317_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.736e-317 983.0
PYH2_k127_1039317_10 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 402.0
PYH2_k127_1039317_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 379.0
PYH2_k127_1039317_12 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 346.0
PYH2_k127_1039317_13 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 349.0
PYH2_k127_1039317_14 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004997 249.0
PYH2_k127_1039317_16 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000003962 134.0
PYH2_k127_1039317_17 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000006406 138.0
PYH2_k127_1039317_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.000000000000000000000001047 107.0
PYH2_k127_1039317_19 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000004483 98.0
PYH2_k127_1039317_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.095e-280 869.0
PYH2_k127_1039317_20 - - - - 0.00000000000000001297 84.0
PYH2_k127_1039317_21 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000005589 76.0
PYH2_k127_1039317_22 - - - - 0.00000000008981 63.0
PYH2_k127_1039317_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.879e-262 814.0
PYH2_k127_1039317_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.916e-211 662.0
PYH2_k127_1039317_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 529.0
PYH2_k127_1039317_6 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 497.0
PYH2_k127_1039317_7 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 471.0
PYH2_k127_1039317_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 457.0
PYH2_k127_1039317_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 421.0
PYH2_k127_1041210_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1148.0
PYH2_k127_1041210_1 His Kinase A (phosphoacceptor) domain - - - 5.375e-317 988.0
PYH2_k127_1041210_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 451.0
PYH2_k127_1041210_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 439.0
PYH2_k127_1041210_12 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 387.0
PYH2_k127_1041210_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000343 201.0
PYH2_k127_1041210_15 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000000004181 162.0
PYH2_k127_1041210_2 Cytochrome c K00405 - - 3.75e-305 944.0
PYH2_k127_1041210_3 aerobic electron transport chain K00425,K08738 - 1.10.3.14 7.991e-279 876.0
PYH2_k127_1041210_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 9.532e-265 825.0
PYH2_k127_1041210_5 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 7.991e-248 777.0
PYH2_k127_1041210_6 Cytochrome c K00405 - - 3.496e-200 631.0
PYH2_k127_1041210_7 phosphorelay signal transduction system - - - 3.299e-196 623.0
PYH2_k127_1041210_8 Cytochrome c - - - 1.848e-194 610.0
PYH2_k127_1041210_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 530.0
PYH2_k127_1059109_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.227e-237 739.0
PYH2_k127_1059109_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 358.0
PYH2_k127_1059109_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 342.0
PYH2_k127_1059109_3 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
PYH2_k127_1059109_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000001312 208.0
PYH2_k127_1059109_5 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000000006023 151.0
PYH2_k127_1059109_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000003717 114.0
PYH2_k127_1059109_7 Protein of unknown function (DUF465) K09794 - - 0.00000000000000005312 83.0
PYH2_k127_1066772_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 579.0
PYH2_k127_1067808_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 2.869e-197 622.0
PYH2_k127_1067808_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 609.0
PYH2_k127_1067808_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 402.0
PYH2_k127_1067808_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 334.0
PYH2_k127_1067808_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000163 282.0
PYH2_k127_1067808_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000001232 74.0
PYH2_k127_1144844_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.191e-230 717.0
PYH2_k127_1144844_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 8.067e-211 661.0
PYH2_k127_1144844_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 377.0
PYH2_k127_1144844_11 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 348.0
PYH2_k127_1144844_12 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 333.0
PYH2_k127_1144844_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
PYH2_k127_1144844_14 cell adhesion K02650 - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
PYH2_k127_1144844_15 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000008619 238.0
PYH2_k127_1144844_17 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000002461 130.0
PYH2_k127_1144844_19 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0000000000000000000002405 99.0
PYH2_k127_1144844_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 9.125e-200 629.0
PYH2_k127_1144844_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.056e-199 629.0
PYH2_k127_1144844_4 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 494.0
PYH2_k127_1144844_5 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 467.0
PYH2_k127_1144844_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 456.0
PYH2_k127_1144844_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 446.0
PYH2_k127_1144844_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 415.0
PYH2_k127_1144844_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 396.0
PYH2_k127_1191884_0 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 518.0
PYH2_k127_1191884_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 482.0
PYH2_k127_1191884_10 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 313.0
PYH2_k127_1191884_11 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
PYH2_k127_1191884_12 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005845 274.0
PYH2_k127_1191884_13 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003025 266.0
PYH2_k127_1191884_14 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002362 259.0
PYH2_k127_1191884_15 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000009467 224.0
PYH2_k127_1191884_16 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000002933 223.0
PYH2_k127_1191884_17 deoxyhypusine monooxygenase activity K02632 - 4.4.1.31 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
PYH2_k127_1191884_18 alpha-ribazole phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000003766 205.0
PYH2_k127_1191884_19 response regulator, receiver K02479 - - 0.000000000000000000000000000000000000000000000000000000004394 206.0
PYH2_k127_1191884_2 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
PYH2_k127_1191884_20 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000001516 182.0
PYH2_k127_1191884_23 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000002631 111.0
PYH2_k127_1191884_25 (AIR) carboxylase K06898 - - 0.000000000000000000000001328 111.0
PYH2_k127_1191884_26 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.00000000000000000003651 101.0
PYH2_k127_1191884_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 483.0
PYH2_k127_1191884_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 429.0
PYH2_k127_1191884_5 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 437.0
PYH2_k127_1191884_6 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 403.0
PYH2_k127_1191884_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 398.0
PYH2_k127_1191884_8 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 396.0
PYH2_k127_1191884_9 tRNA 3'-trailer cleavage - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 334.0
PYH2_k127_119202_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 7.293e-290 897.0
PYH2_k127_119202_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.1e-248 773.0
PYH2_k127_119202_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000000248 197.0
PYH2_k127_119202_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 8.637e-228 712.0
PYH2_k127_119202_3 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 452.0
PYH2_k127_119202_4 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 291.0
PYH2_k127_119202_5 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001636 260.0
PYH2_k127_119202_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 231.0
PYH2_k127_119202_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002174 230.0
PYH2_k127_119202_8 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000004994 228.0
PYH2_k127_119202_9 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000000000000000000000000000000000001394 206.0
PYH2_k127_1217923_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 2.295e-254 809.0
PYH2_k127_1217923_1 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 414.0
PYH2_k127_1217923_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 299.0
PYH2_k127_1217923_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001955 284.0
PYH2_k127_1217923_5 Cytochrome c - - - 0.00000000000000000000000000000000000000009883 156.0
PYH2_k127_1331290_0 Elongation factor G C-terminus K06207 - - 0.0 1010.0
PYH2_k127_1331290_1 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 297.0
PYH2_k127_1331290_3 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000001083 196.0
PYH2_k127_1433800_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 391.0
PYH2_k127_1433800_1 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000002145 258.0
PYH2_k127_1433800_3 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000003126 158.0
PYH2_k127_1433800_4 Zincin-like metallopeptidase - - - 0.000000000000000000006028 92.0
PYH2_k127_1433800_5 gas vesicle protein - - - 0.000000000000001284 81.0
PYH2_k127_1473676_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 428.0
PYH2_k127_1473676_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 342.0
PYH2_k127_1473676_10 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000182 97.0
PYH2_k127_1473676_2 thiolester hydrolase activity K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 289.0
PYH2_k127_1473676_3 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 287.0
PYH2_k127_1473676_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000009131 184.0
PYH2_k127_1580585_0 sulfuric ester hydrolase activity K01002,K01138 - 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 610.0
PYH2_k127_1640803_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1191.0
PYH2_k127_1640803_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00982,K00990 - 2.7.7.42,2.7.7.59,2.7.7.89 0.0 1185.0
PYH2_k127_1640803_10 ANTAR - - - 4.331e-214 673.0
PYH2_k127_1640803_11 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 6.414e-199 634.0
PYH2_k127_1640803_12 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 631.0
PYH2_k127_1640803_13 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 608.0
PYH2_k127_1640803_14 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 598.0
PYH2_k127_1640803_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 599.0
PYH2_k127_1640803_16 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 576.0
PYH2_k127_1640803_17 NMT1-like family K02051,K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 570.0
PYH2_k127_1640803_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 513.0
PYH2_k127_1640803_19 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 477.0
PYH2_k127_1640803_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.392e-308 949.0
PYH2_k127_1640803_20 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 477.0
PYH2_k127_1640803_21 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 472.0
PYH2_k127_1640803_22 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 469.0
PYH2_k127_1640803_23 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 445.0
PYH2_k127_1640803_24 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 428.0
PYH2_k127_1640803_25 photosynthesis K02453,K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 419.0
PYH2_k127_1640803_26 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 390.0
PYH2_k127_1640803_27 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 410.0
PYH2_k127_1640803_28 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 396.0
PYH2_k127_1640803_29 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 390.0
PYH2_k127_1640803_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.089e-284 876.0
PYH2_k127_1640803_30 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 379.0
PYH2_k127_1640803_31 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 372.0
PYH2_k127_1640803_32 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 382.0
PYH2_k127_1640803_33 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 381.0
PYH2_k127_1640803_34 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 370.0
PYH2_k127_1640803_35 PFAM ABC transporter K02049,K15578,K15579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 366.0
PYH2_k127_1640803_36 Binding-protein-dependent transport system inner membrane component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 355.0
PYH2_k127_1640803_37 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 353.0
PYH2_k127_1640803_38 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 330.0
PYH2_k127_1640803_39 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 320.0
PYH2_k127_1640803_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 1.175e-270 852.0
PYH2_k127_1640803_40 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 314.0
PYH2_k127_1640803_41 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 327.0
PYH2_k127_1640803_42 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 315.0
PYH2_k127_1640803_43 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 302.0
PYH2_k127_1640803_44 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 291.0
PYH2_k127_1640803_45 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 289.0
PYH2_k127_1640803_46 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
PYH2_k127_1640803_47 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003656 259.0
PYH2_k127_1640803_48 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 270.0
PYH2_k127_1640803_49 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001257 256.0
PYH2_k127_1640803_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.173e-265 826.0
PYH2_k127_1640803_50 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
PYH2_k127_1640803_51 Cytochrome b(N-terminal)/b6/petB K00412,K02635,K02637,K03887,K03891,K15879 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006867 263.0
PYH2_k127_1640803_52 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
PYH2_k127_1640803_53 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006704 254.0
PYH2_k127_1640803_54 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004611 241.0
PYH2_k127_1640803_55 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001379 237.0
PYH2_k127_1640803_56 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000001915 235.0
PYH2_k127_1640803_57 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
PYH2_k127_1640803_58 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000004092 221.0
PYH2_k127_1640803_59 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
PYH2_k127_1640803_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.119e-255 792.0
PYH2_k127_1640803_60 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000001664 223.0
PYH2_k127_1640803_61 Protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000000000000000000001357 205.0
PYH2_k127_1640803_62 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000001455 201.0
PYH2_k127_1640803_63 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000001634 202.0
PYH2_k127_1640803_64 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000001404 189.0
PYH2_k127_1640803_65 Two component signalling adaptor domain K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000007627 200.0
PYH2_k127_1640803_66 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000715 186.0
PYH2_k127_1640803_67 methyltransferase activity K21377 - 2.1.1.302 0.0000000000000000000000000000000000000000000000000008211 197.0
PYH2_k127_1640803_68 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000589 187.0
PYH2_k127_1640803_69 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001078 180.0
PYH2_k127_1640803_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.171e-249 774.0
PYH2_k127_1640803_70 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000001641 177.0
PYH2_k127_1640803_71 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000002644 177.0
PYH2_k127_1640803_72 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000005431 175.0
PYH2_k127_1640803_73 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000005353 171.0
PYH2_k127_1640803_74 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000000007929 175.0
PYH2_k127_1640803_76 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000001608 166.0
PYH2_k127_1640803_77 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000376 160.0
PYH2_k127_1640803_78 chemotaxis K03408,K03415 - - 0.00000000000000000000000000000000000000003873 157.0
PYH2_k127_1640803_79 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000005684 151.0
PYH2_k127_1640803_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.561e-219 688.0
PYH2_k127_1640803_80 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000004488 135.0
PYH2_k127_1640803_81 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000001716 132.0
PYH2_k127_1640803_82 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000006623 137.0
PYH2_k127_1640803_83 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000266 124.0
PYH2_k127_1640803_84 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.0000000000000000000000000000009296 123.0
PYH2_k127_1640803_85 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000001143 121.0
PYH2_k127_1640803_86 GYD domain - - - 0.000000000000000000000000001307 114.0
PYH2_k127_1640803_88 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000004638 107.0
PYH2_k127_1640803_89 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.000000000000000000000005309 102.0
PYH2_k127_1640803_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.035e-218 681.0
PYH2_k127_1640803_90 30S ribosomal protein S14 K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001168 97.0
PYH2_k127_1640803_92 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000003504 85.0
PYH2_k127_1640803_93 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003438 78.0
PYH2_k127_1640803_94 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000008185 71.0
PYH2_k127_1640803_95 protein conserved in bacteria - - - 0.0000000009961 64.0
PYH2_k127_1675758_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 368.0
PYH2_k127_1675758_1 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 301.0
PYH2_k127_1675758_2 Histidine kinase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
PYH2_k127_1675758_3 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
PYH2_k127_1675758_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003411 200.0
PYH2_k127_1675758_5 Protein of unknown function (DUF3015) - - - 0.0000000000000003914 83.0
PYH2_k127_1688054_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 534.0
PYH2_k127_1688054_1 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 297.0
PYH2_k127_1688054_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000003226 235.0
PYH2_k127_1688054_3 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000003931 169.0
PYH2_k127_1688054_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000003131 161.0
PYH2_k127_1688054_5 PFAM CHAD domain containing protein K08296 - - 0.000000000000000000000000000000000003313 150.0
PYH2_k127_1688054_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.00000000000000000000000000000005312 127.0
PYH2_k127_1688054_7 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000001289 51.0
PYH2_k127_1692207_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.057e-238 741.0
PYH2_k127_1692207_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 557.0
PYH2_k127_1692207_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 534.0
PYH2_k127_1692207_3 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 511.0
PYH2_k127_1692207_4 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 424.0
PYH2_k127_1692207_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 406.0
PYH2_k127_1692207_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 401.0
PYH2_k127_1692207_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000001218 61.0
PYH2_k127_1730980_0 Type II/IV secretion system protein K02454,K02652 - - 0.0 1055.0
PYH2_k127_1730980_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.173e-273 848.0
PYH2_k127_1730980_10 Domain of unknown function (DUF4384) - - - 0.00000000000000000000000000000000000156 151.0
PYH2_k127_1730980_2 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 438.0
PYH2_k127_1730980_3 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 438.0
PYH2_k127_1730980_4 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 330.0
PYH2_k127_1730980_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 304.0
PYH2_k127_1730980_6 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003464 297.0
PYH2_k127_1730980_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002017 248.0
PYH2_k127_1730980_8 Lipoprotein - - - 0.000000000000000000000000000000000000000009526 164.0
PYH2_k127_1730980_9 - - - - 0.0000000000000000000000000000000000000000394 164.0
PYH2_k127_1739172_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
PYH2_k127_1739172_2 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002423 266.0
PYH2_k127_1739172_3 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.00000000000000000000000000000002528 140.0
PYH2_k127_1780473_0 Belongs to the citrate synthase family K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.0 1112.0
PYH2_k127_1780473_1 ATP citrate lyase citrate-binding K15231 - 2.3.3.8 1.946e-219 684.0
PYH2_k127_1780473_2 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 349.0
PYH2_k127_1780473_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
PYH2_k127_1780473_5 phosphatase - - - 0.0000000000000000000000000000000000002613 146.0
PYH2_k127_1780473_6 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000001081 122.0
PYH2_k127_1890210_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 351.0
PYH2_k127_1890210_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 347.0
PYH2_k127_1890210_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001047 148.0
PYH2_k127_1890210_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000003497 139.0
PYH2_k127_1890210_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000008978 119.0
PYH2_k127_1894233_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 1.005e-269 840.0
PYH2_k127_1894233_1 Pfam Fatty acid - - - 3.147e-252 814.0
PYH2_k127_1894233_10 Dodecin K09165 - - 0.00000000000000000000016 99.0
PYH2_k127_1894233_11 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000518 101.0
PYH2_k127_1894233_12 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000008271 99.0
PYH2_k127_1894233_13 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000000000000003218 90.0
PYH2_k127_1894233_14 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000051 78.0
PYH2_k127_1894233_15 - - - - 0.000000000002538 68.0
PYH2_k127_1894233_16 - - - - 0.00000000002797 71.0
PYH2_k127_1894233_19 Protein of unknown function (DUF1328) - - - 0.00001405 48.0
PYH2_k127_1894233_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.215e-222 702.0
PYH2_k127_1894233_3 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 487.0
PYH2_k127_1894233_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
PYH2_k127_1894233_5 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 274.0
PYH2_k127_1894233_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000009079 222.0
PYH2_k127_1894233_7 WYL domain - - - 0.000000000000000000000000000000000000000000000002156 181.0
PYH2_k127_1894233_8 - - - - 0.00000000000000000000000000000000008188 135.0
PYH2_k127_1894233_9 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000001313 128.0
PYH2_k127_1899017_0 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000005334 247.0
PYH2_k127_1899017_1 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
PYH2_k127_1899017_2 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000004912 77.0
PYH2_k127_1910755_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 507.0
PYH2_k127_1910755_1 PFAM Resolvase - - - 0.0000000000000000000000000000000000000000000000000000000000000004601 224.0
PYH2_k127_1910755_2 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000001136 196.0
PYH2_k127_1910755_3 - - - - 0.000000000000000000007217 108.0
PYH2_k127_1966193_0 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 444.0
PYH2_k127_1966193_1 Pup-ligase protein K13571 - 6.3.1.19 0.0000000000000000003271 89.0
PYH2_k127_1966193_2 serine threonine protein kinase - - - 0.000000000000005283 81.0
PYH2_k127_1966193_3 - - - - 0.0000000000004052 74.0
PYH2_k127_2016461_0 PFAM CheB methylesterase - - - 1.196e-299 944.0
PYH2_k127_2016621_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 6.812e-215 676.0
PYH2_k127_2016621_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 479.0
PYH2_k127_2016621_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 457.0
PYH2_k127_2016621_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 447.0
PYH2_k127_2016621_4 Protein of unknown function (DUF692) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 447.0
PYH2_k127_2016621_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 396.0
PYH2_k127_2016621_6 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 334.0
PYH2_k127_2016621_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001968 228.0
PYH2_k127_2016621_8 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000765 226.0
PYH2_k127_2016621_9 efflux transmembrane transporter activity - - - 0.0000000000000000004552 97.0
PYH2_k127_2019913_0 alpha amylase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 504.0
PYH2_k127_2019913_1 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 510.0
PYH2_k127_2019913_2 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003854 275.0
PYH2_k127_2019913_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005858 273.0
PYH2_k127_2019913_4 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000007029 222.0
PYH2_k127_2019913_5 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000001483 174.0
PYH2_k127_2019913_6 Ion channel - - - 0.000000000000000000000000000000000000000000004109 173.0
PYH2_k127_2019913_7 Sugar efflux transporter for intercellular exchange - - - 0.000000000000000000000000000000000000001729 150.0
PYH2_k127_2019913_8 OmpA family K02557 - - 0.0000000000000000000000000001319 127.0
PYH2_k127_2019913_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0001509 53.0
PYH2_k127_2023868_0 Conserved carboxylase domain K01960 - 6.4.1.1 1.245e-308 955.0
PYH2_k127_2023868_1 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 8.943e-261 808.0
PYH2_k127_2023868_10 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 333.0
PYH2_k127_2023868_11 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 310.0
PYH2_k127_2023868_12 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000082 253.0
PYH2_k127_2023868_13 ADP-glyceromanno-heptose 6-epimerase activity K00311 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002861 266.0
PYH2_k127_2023868_15 sirohydrochlorin cobaltochelatase activity - - - 0.000000000000000000000000000000000000000000000000000000004272 203.0
PYH2_k127_2023868_16 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000001298 203.0
PYH2_k127_2023868_17 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000001963 201.0
PYH2_k127_2023868_19 light absorption K01822,K21972 - 5.3.3.1 0.00000000000000000000000000000000000009092 153.0
PYH2_k127_2023868_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 4.495e-199 632.0
PYH2_k127_2023868_20 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000299 146.0
PYH2_k127_2023868_21 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000006108 141.0
PYH2_k127_2023868_22 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000004422 128.0
PYH2_k127_2023868_25 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000002411 111.0
PYH2_k127_2023868_3 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 591.0
PYH2_k127_2023868_4 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 540.0
PYH2_k127_2023868_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 477.0
PYH2_k127_2023868_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 372.0
PYH2_k127_2023868_7 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 366.0
PYH2_k127_2023868_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 353.0
PYH2_k127_2023868_9 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 354.0
PYH2_k127_2026674_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1446.0
PYH2_k127_2026674_1 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.0 1183.0
PYH2_k127_2026674_10 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 527.0
PYH2_k127_2026674_11 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 507.0
PYH2_k127_2026674_12 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 490.0
PYH2_k127_2026674_13 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 447.0
PYH2_k127_2026674_14 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 429.0
PYH2_k127_2026674_15 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002788 268.0
PYH2_k127_2026674_16 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005378 271.0
PYH2_k127_2026674_18 heat shock protein binding K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000003306 209.0
PYH2_k127_2026674_19 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000008007 172.0
PYH2_k127_2026674_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1143.0
PYH2_k127_2026674_20 - - - - 0.000000000000000000000000000000000000000004212 156.0
PYH2_k127_2026674_21 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000196 152.0
PYH2_k127_2026674_24 denitrification pathway - - - 0.0000000000000000000000000000000000185 137.0
PYH2_k127_2026674_28 Small metal-binding protein - - - 0.00000000000000002303 86.0
PYH2_k127_2026674_3 DNA topoisomerase II activity K03167 - 5.99.1.3 1.11e-309 960.0
PYH2_k127_2026674_4 metalloendopeptidase activity K08602 - - 7.249e-264 824.0
PYH2_k127_2026674_5 denitrification pathway - - - 7.105e-232 722.0
PYH2_k127_2026674_6 efflux transmembrane transporter activity K12340 - - 1.248e-224 706.0
PYH2_k127_2026674_7 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 5.01e-220 685.0
PYH2_k127_2026674_8 denitrification pathway - - - 9.414e-199 626.0
PYH2_k127_2026674_9 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 587.0
PYH2_k127_2072220_0 Evidence 4 Homologs of previously reported genes of - - - 1.11e-225 706.0
PYH2_k127_2072220_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 373.0
PYH2_k127_2072220_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000003625 52.0
PYH2_k127_207601_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 380.0
PYH2_k127_207601_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 344.0
PYH2_k127_207601_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 301.0
PYH2_k127_207601_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001364 252.0
PYH2_k127_207601_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000001143 121.0
PYH2_k127_207601_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000007393 86.0
PYH2_k127_207601_6 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000001892 83.0
PYH2_k127_2107337_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 507.0
PYH2_k127_2107337_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 486.0
PYH2_k127_2107337_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 296.0
PYH2_k127_2107337_3 SprT-like family K02742 - - 0.000000000000000000000000000000000000000000000000005278 195.0
PYH2_k127_2107337_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000001096 173.0
PYH2_k127_2107337_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000006698 161.0
PYH2_k127_212451_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 570.0
PYH2_k127_212451_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000004001 183.0
PYH2_k127_212451_2 energy transducer activity K03646,K03832 - - 0.000000000000000000000000008583 115.0
PYH2_k127_212451_3 Transposase K01991,K02557,K07161,K07484 - - 0.000000000000000004023 96.0
PYH2_k127_215418_0 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 538.0
PYH2_k127_215418_1 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 461.0
PYH2_k127_215418_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000003404 190.0
PYH2_k127_215418_11 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000008554 188.0
PYH2_k127_215418_12 - - - - 0.00000000000000000000000000000000000000000000000001338 184.0
PYH2_k127_215418_13 - - - - 0.0000000000000000000000000000000000000000000000002454 177.0
PYH2_k127_215418_14 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000198 172.0
PYH2_k127_215418_15 - - - - 0.0000000000000000000000000000000000000000001742 162.0
PYH2_k127_215418_16 - K14588 - - 0.00000000000000000000000000000000000000003248 156.0
PYH2_k127_215418_18 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000004843 129.0
PYH2_k127_215418_19 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000005525 103.0
PYH2_k127_215418_2 transmembrane transport K02532,K05820,K08167,K08218,K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 462.0
PYH2_k127_215418_20 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000001979 91.0
PYH2_k127_215418_21 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000399 85.0
PYH2_k127_215418_22 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000007127 82.0
PYH2_k127_215418_23 - - - - 0.0003166 44.0
PYH2_k127_215418_3 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 406.0
PYH2_k127_215418_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 372.0
PYH2_k127_215418_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 346.0
PYH2_k127_215418_6 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 293.0
PYH2_k127_215418_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004218 271.0
PYH2_k127_215418_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002725 266.0
PYH2_k127_2161242_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 4.007e-258 807.0
PYH2_k127_2161242_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 452.0
PYH2_k127_2161242_2 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 419.0
PYH2_k127_2161242_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 422.0
PYH2_k127_2161242_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 355.0
PYH2_k127_2161242_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000003753 232.0
PYH2_k127_2161242_6 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000002484 229.0
PYH2_k127_2161242_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000004975 76.0
PYH2_k127_2229710_0 peptidyl-tyrosine sulfation - - - 2.034e-212 676.0
PYH2_k127_2229710_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 446.0
PYH2_k127_2229710_10 YtxH-like protein - - - 0.00000001773 60.0
PYH2_k127_2229710_11 Antibiotic biosynthesis monooxygenase - - - 0.00000005502 60.0
PYH2_k127_2229710_12 Antibiotic biosynthesis monooxygenase - - - 0.00000007449 60.0
PYH2_k127_2229710_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 430.0
PYH2_k127_2229710_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
PYH2_k127_2229710_4 - - - - 0.000000000000000000000000000000000000000000002136 175.0
PYH2_k127_2229710_5 VIT family - - - 0.000000000000000000000000003084 125.0
PYH2_k127_2290962_0 Bacterial extracellular solute-binding protein K10938 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 325.0
PYH2_k127_2290962_1 Sulphur transport K07112 - - 0.000000000000000000000002427 104.0
PYH2_k127_2290962_2 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.0003497 47.0
PYH2_k127_2294297_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 7.814e-268 850.0
PYH2_k127_2294297_1 actin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 522.0
PYH2_k127_2294297_2 Histidine kinase K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003409 282.0
PYH2_k127_2294297_3 Tellurite resistance protein tehB K05524,K06886 - - 0.00000000000000000001744 100.0
PYH2_k127_2362917_0 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 400.0
PYH2_k127_2362917_1 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000003095 250.0
PYH2_k127_2362917_2 diguanylate cyclase - - - 0.00000000000000000001845 102.0
PYH2_k127_2587396_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1321.0
PYH2_k127_2587396_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1101.0
PYH2_k127_2587396_2 FAD binding domain K00239 - 1.3.5.1,1.3.5.4 4.011e-289 893.0
PYH2_k127_2587396_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 598.0
PYH2_k127_2587396_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 415.0
PYH2_k127_2785278_0 Baseplate J-like protein - - - 1.923e-227 723.0
PYH2_k127_2785278_1 Gene 25-like lysozyme K06903 - - 0.0000000000000007035 78.0
PYH2_k127_2813092_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 307.0
PYH2_k127_2832331_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1485.0
PYH2_k127_2832331_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 474.0
PYH2_k127_2832331_10 - - - - 0.00000000000000000000000000000000000000000000000000000001168 207.0
PYH2_k127_2832331_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.0000000000000000000000000000000000000001103 156.0
PYH2_k127_2832331_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 465.0
PYH2_k127_2832331_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 354.0
PYH2_k127_2832331_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 323.0
PYH2_k127_2832331_5 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 298.0
PYH2_k127_2832331_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007712 261.0
PYH2_k127_2832331_7 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006508 241.0
PYH2_k127_2832331_8 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000001012 211.0
PYH2_k127_2832331_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003713 201.0
PYH2_k127_2843025_0 exporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001453 292.0
PYH2_k127_2843025_1 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005215 279.0
PYH2_k127_2843025_2 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 279.0
PYH2_k127_2843025_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000001176 124.0
PYH2_k127_2843025_4 FabA-like domain - - - 0.00000000000006882 76.0
PYH2_k127_2870905_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 417.0
PYH2_k127_2870905_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000184 275.0
PYH2_k127_2870905_2 Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000003846 191.0
PYH2_k127_289059_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1049.0
PYH2_k127_289059_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 626.0
PYH2_k127_289059_2 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 520.0
PYH2_k127_289059_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 396.0
PYH2_k127_289059_4 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 354.0
PYH2_k127_289059_5 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 347.0
PYH2_k127_289059_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
PYH2_k127_289059_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000007221 222.0
PYH2_k127_289059_8 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.0000000000000000000000000000000000000000000000000000000259 206.0
PYH2_k127_2939463_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 389.0
PYH2_k127_2939463_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 353.0
PYH2_k127_2960023_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0 1027.0
PYH2_k127_2960023_1 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000001927 192.0
PYH2_k127_2960023_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000161 107.0
PYH2_k127_2960023_3 FecR protein - - - 0.0000000000002108 80.0
PYH2_k127_2960023_4 - - - - 0.000004739 52.0
PYH2_k127_2986504_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 518.0
PYH2_k127_2986504_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 481.0
PYH2_k127_2986504_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 466.0
PYH2_k127_2986504_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 329.0
PYH2_k127_2986504_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000006731 258.0
PYH2_k127_2986504_5 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
PYH2_k127_2986504_6 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000008964 244.0
PYH2_k127_2986504_7 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.00000000000000000000000308 106.0
PYH2_k127_2986504_8 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000004161 115.0
PYH2_k127_2986504_9 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000008033 84.0
PYH2_k127_2996426_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1054.0
PYH2_k127_2996426_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1027.0
PYH2_k127_2996426_10 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 573.0
PYH2_k127_2996426_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 473.0
PYH2_k127_2996426_12 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 468.0
PYH2_k127_2996426_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 436.0
PYH2_k127_2996426_14 Cytochrome c K02305,K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 434.0
PYH2_k127_2996426_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 421.0
PYH2_k127_2996426_16 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 402.0
PYH2_k127_2996426_17 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 377.0
PYH2_k127_2996426_18 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 362.0
PYH2_k127_2996426_19 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 346.0
PYH2_k127_2996426_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.705e-321 989.0
PYH2_k127_2996426_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 319.0
PYH2_k127_2996426_21 Cytochrome c K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 312.0
PYH2_k127_2996426_22 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 304.0
PYH2_k127_2996426_23 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
PYH2_k127_2996426_24 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 294.0
PYH2_k127_2996426_25 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 294.0
PYH2_k127_2996426_26 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
PYH2_k127_2996426_27 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002127 268.0
PYH2_k127_2996426_28 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002533 266.0
PYH2_k127_2996426_29 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 261.0
PYH2_k127_2996426_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 2.219e-256 792.0
PYH2_k127_2996426_30 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
PYH2_k127_2996426_32 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001419 177.0
PYH2_k127_2996426_33 - - - - 0.00000000000000000000000000000000000000000004305 164.0
PYH2_k127_2996426_34 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000004323 162.0
PYH2_k127_2996426_35 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000008368 164.0
PYH2_k127_2996426_37 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000003688 124.0
PYH2_k127_2996426_38 Evidence 5 No homology to any previously reported sequences K07126 - - 0.00000000000000000000000000005172 124.0
PYH2_k127_2996426_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.012e-255 792.0
PYH2_k127_2996426_40 YCII-related domain K09780 - - 0.00000000000000000001118 94.0
PYH2_k127_2996426_41 long-chain fatty acid transporting porin activity - - - 0.000000000000000006493 83.0
PYH2_k127_2996426_42 PFAM IS1 transposase K07480 - - 0.000000000000354 82.0
PYH2_k127_2996426_43 PFAM IS1 transposase K07480 - - 0.00000002817 55.0
PYH2_k127_2996426_44 TPR repeat - - - 0.00004077 56.0
PYH2_k127_2996426_5 Cytochrome b/b6/petB K00412 - - 1.583e-220 685.0
PYH2_k127_2996426_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 5.345e-216 674.0
PYH2_k127_2996426_7 Domain of unknown function (DUF3463) - - - 1.862e-207 647.0
PYH2_k127_2996426_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 3.307e-197 627.0
PYH2_k127_2996426_9 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 605.0
PYH2_k127_2997583_0 PD-(D/E)XK nuclease superfamily - - - 0.0 1178.0
PYH2_k127_2997583_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.707e-309 962.0
PYH2_k127_2997583_10 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 511.0
PYH2_k127_2997583_11 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 451.0
PYH2_k127_2997583_12 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 391.0
PYH2_k127_2997583_13 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 378.0
PYH2_k127_2997583_14 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 337.0
PYH2_k127_2997583_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 334.0
PYH2_k127_2997583_16 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 305.0
PYH2_k127_2997583_17 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000973 268.0
PYH2_k127_2997583_18 regulation of RNA biosynthetic process K03567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002072 253.0
PYH2_k127_2997583_19 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000009227 231.0
PYH2_k127_2997583_2 exonuclease activity K16899 - 3.6.4.12 5.543e-308 976.0
PYH2_k127_2997583_20 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000008673 163.0
PYH2_k127_2997583_21 ACT domain - - - 0.0000000000000000000000000000000000000005845 152.0
PYH2_k127_2997583_22 LysM domain - - - 0.0000000000000000000000000000102 125.0
PYH2_k127_2997583_23 - - - - 0.000000000000000000002817 98.0
PYH2_k127_2997583_24 photosynthesis - - - 0.000000000000000009459 89.0
PYH2_k127_2997583_25 protein conserved in bacteria - - - 0.00000002085 59.0
PYH2_k127_2997583_3 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.675e-266 825.0
PYH2_k127_2997583_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 5.351e-249 776.0
PYH2_k127_2997583_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.141e-218 680.0
PYH2_k127_2997583_6 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 588.0
PYH2_k127_2997583_7 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 573.0
PYH2_k127_2997583_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 542.0
PYH2_k127_2997583_9 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
PYH2_k127_3015089_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.894e-204 644.0
PYH2_k127_3015089_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 505.0
PYH2_k127_3015089_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000000000006494 153.0
PYH2_k127_3073386_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1304.0
PYH2_k127_3073386_1 Surface antigen K07277 - - 1.095e-298 935.0
PYH2_k127_3073386_10 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000002425 210.0
PYH2_k127_3073386_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000000000000000000003932 188.0
PYH2_k127_3073386_12 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000002651 182.0
PYH2_k127_3073386_13 Outer membrane lipoprotein Slp family K07285 - - 0.00000006208 62.0
PYH2_k127_3073386_14 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00007302 46.0
PYH2_k127_3073386_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 1.618e-272 841.0
PYH2_k127_3073386_3 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 3.43e-245 765.0
PYH2_k127_3073386_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 3.934e-217 685.0
PYH2_k127_3073386_5 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 438.0
PYH2_k127_3073386_6 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 387.0
PYH2_k127_3073386_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 359.0
PYH2_k127_3073386_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 336.0
PYH2_k127_3073386_9 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 314.0
PYH2_k127_3211602_0 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 546.0
PYH2_k127_3211602_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 486.0
PYH2_k127_3211602_10 Protein of unknown function (DUF805) - - - 0.000006181 57.0
PYH2_k127_3211602_2 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 432.0
PYH2_k127_3211602_3 pectinesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 402.0
PYH2_k127_3211602_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
PYH2_k127_3211602_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000004974 182.0
PYH2_k127_3211602_7 negative regulation of translational initiation K05554,K14670,K15886 - 2.3.1.235 0.00000000000000000000000000000002896 134.0
PYH2_k127_3211602_9 - - - - 0.0000002265 54.0
PYH2_k127_3253130_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1465.0
PYH2_k127_3253130_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1100.0
PYH2_k127_3253130_10 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 529.0
PYH2_k127_3253130_11 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 478.0
PYH2_k127_3253130_12 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 480.0
PYH2_k127_3253130_13 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 474.0
PYH2_k127_3253130_14 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
PYH2_k127_3253130_15 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 408.0
PYH2_k127_3253130_16 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 399.0
PYH2_k127_3253130_17 transmembrane transporter activity K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 391.0
PYH2_k127_3253130_18 amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 392.0
PYH2_k127_3253130_19 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 360.0
PYH2_k127_3253130_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 6.234e-311 961.0
PYH2_k127_3253130_20 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 355.0
PYH2_k127_3253130_21 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 316.0
PYH2_k127_3253130_22 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 310.0
PYH2_k127_3253130_23 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
PYH2_k127_3253130_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
PYH2_k127_3253130_26 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000000000000000000000000000000000000000000000001405 212.0
PYH2_k127_3253130_27 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437,K03501 - 2.1.1.170,2.1.1.185 0.000000000000000000000000000000000000000000000000000000000009767 216.0
PYH2_k127_3253130_28 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000336 193.0
PYH2_k127_3253130_29 HD domain - - - 0.00000000000000000000000000000000000000000000000000003541 196.0
PYH2_k127_3253130_3 Protein involved in outer membrane biogenesis K07290 - - 4.847e-271 871.0
PYH2_k127_3253130_31 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000004377 181.0
PYH2_k127_3253130_32 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000003376 172.0
PYH2_k127_3253130_34 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000005687 133.0
PYH2_k127_3253130_36 - - - - 0.000000000000000000000000001151 113.0
PYH2_k127_3253130_38 - - - - 0.00000000000249 72.0
PYH2_k127_3253130_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 6.622e-262 812.0
PYH2_k127_3253130_5 pyruvate decarboxylase activity K04103 - 4.1.1.74 4.123e-258 809.0
PYH2_k127_3253130_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.304e-246 784.0
PYH2_k127_3253130_7 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 607.0
PYH2_k127_3253130_8 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 585.0
PYH2_k127_3253130_9 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 535.0
PYH2_k127_325815_0 Amino acid permease K03294 - - 3.665e-233 729.0
PYH2_k127_325815_1 Sugar (and other) transporter K08178 - - 2.04e-213 669.0
PYH2_k127_325815_10 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000008355 192.0
PYH2_k127_325815_12 - - - - 0.00000000000000000000000000000000000000000000004596 175.0
PYH2_k127_325815_14 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000000000000000000000000002168 154.0
PYH2_k127_325815_2 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 577.0
PYH2_k127_325815_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 486.0
PYH2_k127_325815_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 472.0
PYH2_k127_325815_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 324.0
PYH2_k127_325815_6 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 325.0
PYH2_k127_325815_7 protein secretion K03116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003355 267.0
PYH2_k127_325815_8 Phosphoserine phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001927 236.0
PYH2_k127_325815_9 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000003976 231.0
PYH2_k127_3272134_0 Nitroreductase - - - 1.496e-242 761.0
PYH2_k127_3272134_1 serine threonine protein kinase K12132 - 2.7.11.1 7.93e-224 721.0
PYH2_k127_3272134_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 591.0
PYH2_k127_3272134_3 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 527.0
PYH2_k127_3272134_4 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000003004 187.0
PYH2_k127_3272134_6 Domain of unknown function (DUF3393) - - - 0.000000000000000000000000000000004086 138.0
PYH2_k127_3272134_7 FAD binding domain - - - 0.000000000000000000005188 94.0
PYH2_k127_3272134_9 - - - - 0.0003164 47.0
PYH2_k127_3301817_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1328.0
PYH2_k127_3301817_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1232.0
PYH2_k127_3301817_10 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 469.0
PYH2_k127_3301817_11 peroxidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 434.0
PYH2_k127_3301817_12 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 443.0
PYH2_k127_3301817_13 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 434.0
PYH2_k127_3301817_14 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 411.0
PYH2_k127_3301817_16 transferase activity, transferring hexosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 404.0
PYH2_k127_3301817_17 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 383.0
PYH2_k127_3301817_18 Belongs to the sirtuin family. Class K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 370.0
PYH2_k127_3301817_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 361.0
PYH2_k127_3301817_2 Heat shock 70 kDa protein K04043 - - 0.0 1100.0
PYH2_k127_3301817_20 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 346.0
PYH2_k127_3301817_21 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
PYH2_k127_3301817_22 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 313.0
PYH2_k127_3301817_24 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
PYH2_k127_3301817_25 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
PYH2_k127_3301817_26 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005814 272.0
PYH2_k127_3301817_27 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
PYH2_k127_3301817_28 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000006213 235.0
PYH2_k127_3301817_29 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000007969 203.0
PYH2_k127_3301817_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 3.111e-299 967.0
PYH2_k127_3301817_30 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000005531 198.0
PYH2_k127_3301817_31 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000002776 192.0
PYH2_k127_3301817_33 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000006867 174.0
PYH2_k127_3301817_34 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000004569 173.0
PYH2_k127_3301817_35 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000005087 172.0
PYH2_k127_3301817_36 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000483 164.0
PYH2_k127_3301817_37 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000002921 163.0
PYH2_k127_3301817_38 Psort location Cytoplasmic, score K22227 - - 0.000000000000000000000000000000000000006759 159.0
PYH2_k127_3301817_39 Anti-sigma-K factor rskA K18682 - - 0.00000000000000000000000000000000000187 150.0
PYH2_k127_3301817_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 3.083e-224 702.0
PYH2_k127_3301817_41 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.00000000000000000000000000000001463 132.0
PYH2_k127_3301817_43 Protein of unknown function (DUF1284) K09706 - - 0.00000000000000000000000001349 115.0
PYH2_k127_3301817_44 protein transport across the cell outer membrane - - - 0.0000000000000000000000698 103.0
PYH2_k127_3301817_45 regulation of DNA repair K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.0000000000000000003036 94.0
PYH2_k127_3301817_47 Uncharacterised nucleotidyltransferase - - - 0.00000000000004546 83.0
PYH2_k127_3301817_48 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000005612 64.0
PYH2_k127_3301817_49 methyltransferase - - - 0.000004676 57.0
PYH2_k127_3301817_5 guanyl-nucleotide exchange factor activity - - - 4.829e-223 704.0
PYH2_k127_3301817_50 Psort location Cytoplasmic, score - - - 0.00001253 53.0
PYH2_k127_3301817_51 signal peptide processing K13280 - 3.4.21.89 0.0001309 53.0
PYH2_k127_3301817_52 Tetratricopeptide repeat - - - 0.0002876 48.0
PYH2_k127_3301817_6 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 3.799e-211 667.0
PYH2_k127_3301817_7 serine threonine protein kinase K12132 - 2.7.11.1 1.989e-205 667.0
PYH2_k127_3301817_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 582.0
PYH2_k127_3301817_9 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 477.0
PYH2_k127_332071_0 ABC transporter K06158 - - 5.193e-294 912.0
PYH2_k127_332071_1 radical SAM domain protein - - - 4.831e-292 913.0
PYH2_k127_332071_10 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 421.0
PYH2_k127_332071_11 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 369.0
PYH2_k127_332071_12 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 353.0
PYH2_k127_332071_13 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 319.0
PYH2_k127_332071_14 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
PYH2_k127_332071_15 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
PYH2_k127_332071_16 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001384 265.0
PYH2_k127_332071_17 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005278 246.0
PYH2_k127_332071_18 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000001291 215.0
PYH2_k127_332071_19 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000005886 194.0
PYH2_k127_332071_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.252e-232 723.0
PYH2_k127_332071_20 Domain of unknown function (DUF5069) - - - 0.00000000000000000000000000000000000000000000000000003783 192.0
PYH2_k127_332071_21 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000000000000000000000000000000000000000005125 180.0
PYH2_k127_332071_22 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000005438 194.0
PYH2_k127_332071_23 Cytochrome c K00405 - - 0.0000000000000000000000000000000000000000000001107 172.0
PYH2_k127_332071_25 protein maturation K07390,K13628,K15724 - - 0.00000000000000009479 83.0
PYH2_k127_332071_26 DoxX-like family - - - 0.0000000000000003361 83.0
PYH2_k127_332071_28 - - - - 0.0001496 44.0
PYH2_k127_332071_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.4e-221 693.0
PYH2_k127_332071_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 595.0
PYH2_k127_332071_5 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 538.0
PYH2_k127_332071_6 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 535.0
PYH2_k127_332071_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 489.0
PYH2_k127_332071_8 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 484.0
PYH2_k127_332071_9 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 461.0
PYH2_k127_3354155_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 422.0
PYH2_k127_3354155_1 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004804 245.0
PYH2_k127_3354155_2 Transposase K01991,K02557,K07161,K07484 - - 0.0000000000000000000000000000000000000003229 153.0
PYH2_k127_3364283_0 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 8.352e-258 824.0
PYH2_k127_3364283_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 4.652e-231 724.0
PYH2_k127_3364283_10 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000003623 178.0
PYH2_k127_3364283_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000004912 167.0
PYH2_k127_3364283_12 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000003086 137.0
PYH2_k127_3364283_3 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 369.0
PYH2_k127_3364283_4 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 321.0
PYH2_k127_3364283_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006928 289.0
PYH2_k127_3364283_7 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000008324 241.0
PYH2_k127_3364283_8 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000001024 210.0
PYH2_k127_3364283_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000019 205.0
PYH2_k127_336789_0 COG3119 Arylsulfatase A and related enzymes K01134 - 3.1.6.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 435.0
PYH2_k127_336789_1 - - - - 0.000009186 53.0
PYH2_k127_3397180_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2441.0
PYH2_k127_3397180_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2289.0
PYH2_k127_3397180_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1219.0
PYH2_k127_3397180_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006808 228.0
PYH2_k127_3397180_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004028 225.0
PYH2_k127_3397180_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000001223 133.0
PYH2_k127_3397180_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001986 87.0
PYH2_k127_3397273_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1114.0
PYH2_k127_3397273_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
PYH2_k127_3397273_2 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002397 261.0
PYH2_k127_3397273_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000001376 118.0
PYH2_k127_3397273_4 Domain of unknown function (DUF4321) - - - 0.000000000000000000000001012 106.0
PYH2_k127_3397273_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000006709 86.0
PYH2_k127_3397273_8 - - - - 0.0001945 46.0
PYH2_k127_3409013_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 377.0
PYH2_k127_3409013_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 303.0
PYH2_k127_3409013_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000002411 116.0
PYH2_k127_3460748_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1075.0
PYH2_k127_3460748_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.449e-218 684.0
PYH2_k127_3460748_2 Competence protein K02238 - - 1.19e-207 674.0
PYH2_k127_3460748_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 314.0
PYH2_k127_3460748_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 290.0
PYH2_k127_3460748_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
PYH2_k127_3495085_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.872e-239 752.0
PYH2_k127_3495085_1 PhoQ Sensor - - - 1.506e-217 692.0
PYH2_k127_3495085_2 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 1.752e-210 665.0
PYH2_k127_3495085_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 551.0
PYH2_k127_3495085_4 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 305.0
PYH2_k127_3495085_5 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000000000002565 196.0
PYH2_k127_355037_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.9e-267 830.0
PYH2_k127_355037_1 Homoserine dehydrogenase K00003 - 1.1.1.3 2.651e-217 680.0
PYH2_k127_355037_2 ACT domain K00928 - 2.7.2.4 9.473e-214 668.0
PYH2_k127_355037_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 591.0
PYH2_k127_355037_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 436.0
PYH2_k127_355037_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 366.0
PYH2_k127_355037_6 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000005811 171.0
PYH2_k127_355037_7 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000000000001166 160.0
PYH2_k127_3750304_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1911.0
PYH2_k127_3750304_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 390.0
PYH2_k127_3750304_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 310.0
PYH2_k127_3750304_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000001128 267.0
PYH2_k127_3750304_4 - - - - 0.0000004698 52.0
PYH2_k127_3770497_0 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 393.0
PYH2_k127_3770497_1 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 368.0
PYH2_k127_3770497_2 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000104 189.0
PYH2_k127_3770497_4 Antibiotic biosynthesis monooxygenase - - - 0.0000001456 57.0
PYH2_k127_3770497_5 - - - - 0.00007884 45.0
PYH2_k127_3790075_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1323.0
PYH2_k127_3790075_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000007748 145.0
PYH2_k127_3841640_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 342.0
PYH2_k127_3841640_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 318.0
PYH2_k127_3841640_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000005843 112.0
PYH2_k127_3853008_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 581.0
PYH2_k127_3853008_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 578.0
PYH2_k127_3853008_11 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
PYH2_k127_3853008_12 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001749 212.0
PYH2_k127_3853008_14 - K11477 - - 0.0000000000000000000000000000000000000000000000000000009822 197.0
PYH2_k127_3853008_15 - - - - 0.00000000000000000000000000000000000000000000000000005449 195.0
PYH2_k127_3853008_16 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000006829 175.0
PYH2_k127_3853008_17 ThiS family K03636 - - 0.0000000000000000000000000000000000000001114 152.0
PYH2_k127_3853008_18 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000000000000000002632 152.0
PYH2_k127_3853008_19 NIL - - - 0.00000000000000000000000000000000002633 141.0
PYH2_k127_3853008_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 556.0
PYH2_k127_3853008_20 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000009143 123.0
PYH2_k127_3853008_23 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000000000000001711 100.0
PYH2_k127_3853008_26 Cache domain - - - 0.00000000000003613 85.0
PYH2_k127_3853008_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 494.0
PYH2_k127_3853008_4 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 458.0
PYH2_k127_3853008_5 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 445.0
PYH2_k127_3853008_6 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 419.0
PYH2_k127_3853008_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 313.0
PYH2_k127_3853008_8 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 294.0
PYH2_k127_3853008_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 278.0
PYH2_k127_3885302_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1391.0
PYH2_k127_3885302_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 609.0
PYH2_k127_3927855_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.604e-230 723.0
PYH2_k127_3927855_1 Transglycosylase SLT domain K08309 - - 6.332e-201 649.0
PYH2_k127_3927855_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 449.0
PYH2_k127_3927855_3 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 431.0
PYH2_k127_3927855_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000003194 245.0
PYH2_k127_3927855_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000001361 115.0
PYH2_k127_3965076_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.619e-260 809.0
PYH2_k127_3965076_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.319e-197 619.0
PYH2_k127_3965076_10 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000005069 247.0
PYH2_k127_3965076_11 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000003639 224.0
PYH2_k127_3965076_12 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000002876 208.0
PYH2_k127_3965076_13 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000007365 157.0
PYH2_k127_3965076_14 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000004234 124.0
PYH2_k127_3965076_15 Protein of unknown function (DUF2905) - - - 0.00000000000001117 76.0
PYH2_k127_3965076_2 Actin K03569 - - 6.108e-196 615.0
PYH2_k127_3965076_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 546.0
PYH2_k127_3965076_4 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 463.0
PYH2_k127_3965076_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 451.0
PYH2_k127_3965076_6 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 431.0
PYH2_k127_3965076_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 362.0
PYH2_k127_3965076_8 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 304.0
PYH2_k127_3965076_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002046 279.0
PYH2_k127_3983835_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 439.0
PYH2_k127_3983835_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002923 276.0
PYH2_k127_3983835_2 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000002274 168.0
PYH2_k127_3986616_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0 1253.0
PYH2_k127_3986616_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1054.0
PYH2_k127_3986616_10 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000007323 76.0
PYH2_k127_3986616_2 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 505.0
PYH2_k127_3986616_3 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 439.0
PYH2_k127_3986616_4 sulfate reduction K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 398.0
PYH2_k127_3986616_5 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 286.0
PYH2_k127_3986616_6 2 iron, 2 sulfur cluster binding K04487,K13643 - 2.8.1.7 0.00000000000000000000000000000000000000000000000003494 182.0
PYH2_k127_3986616_7 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000001469 180.0
PYH2_k127_3986616_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000345 175.0
PYH2_k127_3986616_9 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000005943 158.0
PYH2_k127_4069613_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000951 173.0
PYH2_k127_4069613_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000002325 140.0
PYH2_k127_4069613_2 Nucleotidyl transferase - - - 0.0000000000002053 79.0
PYH2_k127_4096792_0 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 345.0
PYH2_k127_4096792_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000001733 161.0
PYH2_k127_4098747_0 Belongs to the carbamoyltransferase HypF family K04656 - - 3.442e-209 678.0
PYH2_k127_4098747_1 Hydrogenase maturation protease - - - 0.000000000000000000000000000000006981 134.0
PYH2_k127_4098747_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000001438 107.0
PYH2_k127_4098747_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00007475 49.0
PYH2_k127_4119014_0 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.0 2222.0
PYH2_k127_4119014_1 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1430.0
PYH2_k127_4119014_10 Belongs to the GPI family K01810 - 5.3.1.9 3.607e-264 824.0
PYH2_k127_4119014_11 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.421e-260 813.0
PYH2_k127_4119014_12 radical SAM domain protein - - - 1.114e-251 790.0
PYH2_k127_4119014_13 Beta-Casp domain K07576 - - 9.096e-229 724.0
PYH2_k127_4119014_14 Sulfate permease family - - - 2.985e-220 706.0
PYH2_k127_4119014_15 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.163e-216 679.0
PYH2_k127_4119014_16 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 2.044e-216 687.0
PYH2_k127_4119014_17 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.788e-211 669.0
PYH2_k127_4119014_18 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 578.0
PYH2_k127_4119014_19 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 552.0
PYH2_k127_4119014_2 Peptidase family M1 domain K08776 - - 0.0 1068.0
PYH2_k127_4119014_20 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 518.0
PYH2_k127_4119014_21 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 506.0
PYH2_k127_4119014_22 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 501.0
PYH2_k127_4119014_23 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 475.0
PYH2_k127_4119014_24 Class V aminotransferase K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 467.0
PYH2_k127_4119014_25 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 451.0
PYH2_k127_4119014_26 FIST C domain - GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 456.0
PYH2_k127_4119014_27 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 434.0
PYH2_k127_4119014_28 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 430.0
PYH2_k127_4119014_29 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 420.0
PYH2_k127_4119014_3 FtsX-like permease family K02004 - - 0.0 1060.0
PYH2_k127_4119014_30 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 402.0
PYH2_k127_4119014_31 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 381.0
PYH2_k127_4119014_33 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 345.0
PYH2_k127_4119014_34 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 346.0
PYH2_k127_4119014_35 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 343.0
PYH2_k127_4119014_36 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 322.0
PYH2_k127_4119014_37 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 306.0
PYH2_k127_4119014_38 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 310.0
PYH2_k127_4119014_39 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 298.0
PYH2_k127_4119014_4 Belongs to the transketolase family K00615 - 2.2.1.1 1.265e-321 996.0
PYH2_k127_4119014_40 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002076 278.0
PYH2_k127_4119014_41 2OG-Fe(II) oxygenase superfamily K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003823 267.0
PYH2_k127_4119014_42 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 268.0
PYH2_k127_4119014_43 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 262.0
PYH2_k127_4119014_44 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
PYH2_k127_4119014_45 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 250.0
PYH2_k127_4119014_46 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000005894 243.0
PYH2_k127_4119014_47 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
PYH2_k127_4119014_49 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000005134 207.0
PYH2_k127_4119014_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 5.955e-302 924.0
PYH2_k127_4119014_50 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000374 208.0
PYH2_k127_4119014_52 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000005965 194.0
PYH2_k127_4119014_53 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000005331 194.0
PYH2_k127_4119014_54 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000003244 174.0
PYH2_k127_4119014_55 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000000004513 166.0
PYH2_k127_4119014_56 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000004611 168.0
PYH2_k127_4119014_57 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000001622 164.0
PYH2_k127_4119014_58 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000001082 143.0
PYH2_k127_4119014_59 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000004376 127.0
PYH2_k127_4119014_6 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.44e-293 912.0
PYH2_k127_4119014_60 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000000000236 119.0
PYH2_k127_4119014_65 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000293 103.0
PYH2_k127_4119014_66 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000008975 104.0
PYH2_k127_4119014_67 PFAM D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000004941 90.0
PYH2_k127_4119014_68 energy transducer activity K03832 - - 0.0000000000000000005901 99.0
PYH2_k127_4119014_69 - - - - 0.00000000000000091 86.0
PYH2_k127_4119014_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.503e-292 902.0
PYH2_k127_4119014_70 - - - - 0.000000000000009422 78.0
PYH2_k127_4119014_72 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000005511 60.0
PYH2_k127_4119014_73 DNA integration - - - 0.0000008931 52.0
PYH2_k127_4119014_8 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.853e-286 886.0
PYH2_k127_4119014_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.09e-283 873.0
PYH2_k127_4146874_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 306.0
PYH2_k127_4146874_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.0000000000000003914 83.0
PYH2_k127_4146874_2 TOBE domain K10112 - - 0.0000000009924 64.0
PYH2_k127_4163051_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 555.0
PYH2_k127_4163051_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001106 251.0
PYH2_k127_4163051_2 peptidoglycan biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000004295 214.0
PYH2_k127_4163051_3 nuclear chromosome segregation - - - 0.00000000000000000000000001012 117.0
PYH2_k127_4180577_0 nodulation K00612 - - 1.359e-252 790.0
PYH2_k127_4180577_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 1.862e-233 726.0
PYH2_k127_4180577_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 398.0
PYH2_k127_4180577_11 denitrification pathway K02569,K03532,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 368.0
PYH2_k127_4180577_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 366.0
PYH2_k127_4180577_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 319.0
PYH2_k127_4180577_14 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 295.0
PYH2_k127_4180577_15 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001398 265.0
PYH2_k127_4180577_16 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005298 263.0
PYH2_k127_4180577_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 238.0
PYH2_k127_4180577_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000004644 212.0
PYH2_k127_4180577_2 Trypsin K04771 - 3.4.21.107 5.973e-220 693.0
PYH2_k127_4180577_20 RNA recognition motif - - - 0.0000000000000000000000000000000000000000009233 160.0
PYH2_k127_4180577_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 595.0
PYH2_k127_4180577_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 523.0
PYH2_k127_4180577_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 508.0
PYH2_k127_4180577_6 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 521.0
PYH2_k127_4180577_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 482.0
PYH2_k127_4180577_8 macromolecule localization K01421,K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 409.0
PYH2_k127_4180577_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 403.0
PYH2_k127_4183534_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 3.37e-280 867.0
PYH2_k127_4183534_1 Evidence 2b Function of strongly homologous gene - - - 6.299e-210 656.0
PYH2_k127_4183534_2 Histidyl-tRNA synthetase K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 451.0
PYH2_k127_4228572_0 Hsp70 protein K04043,K04044 - - 8.676e-308 951.0
PYH2_k127_4228572_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 3.774e-201 655.0
PYH2_k127_4228572_2 DnaJ molecular chaperone homology domain K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000001101 229.0
PYH2_k127_4228572_3 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000000000009748 133.0
PYH2_k127_4229041_0 thiamine transport K02011 - - 1.821e-226 712.0
PYH2_k127_4229041_1 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 510.0
PYH2_k127_4229041_2 ATPase activity K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 496.0
PYH2_k127_4229041_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001122 261.0
PYH2_k127_4229041_4 bacteriocin transport K03561,K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000001934 228.0
PYH2_k127_4229041_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.00000000000000000007958 101.0
PYH2_k127_4229041_6 biopolymer transport protein K03559 - - 0.000000000000000001717 89.0
PYH2_k127_4237484_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1032.0
PYH2_k127_4237484_1 Participates in both transcription termination and antitermination K02600 - - 2.015e-202 635.0
PYH2_k127_4237484_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000001644 176.0
PYH2_k127_4413016_0 metallopeptidase activity K03568 - - 1.786e-242 755.0
PYH2_k127_4413016_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 572.0
PYH2_k127_4460698_0 Aldehyde dehydrogenase family - - - 1.501e-195 617.0
PYH2_k127_4460698_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 523.0
PYH2_k127_4460698_2 arginine decarboxylase activity K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 344.0
PYH2_k127_4485320_0 Glycosyl transferase, family 2 K10012,K12999,K13670 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 432.0
PYH2_k127_4485320_1 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 332.0
PYH2_k127_4485320_2 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
PYH2_k127_4485320_3 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000002161 256.0
PYH2_k127_4485320_4 trans-aconitate 2-methyltransferase activity K02169 GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000533 246.0
PYH2_k127_4485320_5 Glycosyltransferase Family 4 - - - 0.0000000001375 63.0
PYH2_k127_4486050_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1517.0
PYH2_k127_4486050_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 1.263e-253 793.0
PYH2_k127_4486050_10 phosphorelay signal transduction system - - - 0.0000000007581 60.0
PYH2_k127_4486050_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 558.0
PYH2_k127_4486050_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 506.0
PYH2_k127_4486050_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 471.0
PYH2_k127_4486050_5 putrescine transport K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
PYH2_k127_4486050_6 DNA import into cell involved in transformation K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
PYH2_k127_4486050_7 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 294.0
PYH2_k127_4486050_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000007062 262.0
PYH2_k127_4486050_9 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000001322 184.0
PYH2_k127_4491142_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.659e-273 850.0
PYH2_k127_4491142_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 537.0
PYH2_k127_4491142_2 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002543 269.0
PYH2_k127_4491142_3 Belongs to the GPI family K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.000006434 48.0
PYH2_k127_4552917_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 589.0
PYH2_k127_4552917_1 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 411.0
PYH2_k127_4583782_0 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 374.0
PYH2_k127_4583782_1 ABC transporter, ATP-binding protein K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005384 258.0
PYH2_k127_4583782_2 Urea ABC transporter permease K11960 - - 0.000000000000000000000000003203 111.0
PYH2_k127_4721469_0 Tetratricopeptide repeat - - - 5.755e-214 681.0
PYH2_k127_4721469_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 2.14e-211 667.0
PYH2_k127_4721469_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000002041 251.0
PYH2_k127_4721469_3 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000000000000000000000731 122.0
PYH2_k127_4721469_4 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000009988 59.0
PYH2_k127_473368_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 447.0
PYH2_k127_473368_1 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 438.0
PYH2_k127_473368_2 cobalamin binding K21089,K21972,K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 374.0
PYH2_k127_473368_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000009423 261.0
PYH2_k127_473368_4 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000001432 199.0
PYH2_k127_4771596_0 homolog of phage Mu protein gp47 - - - 1.096e-244 777.0
PYH2_k127_4771596_1 TIGRFAM phage tail protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 586.0
PYH2_k127_4771596_2 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 348.0
PYH2_k127_4771596_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 346.0
PYH2_k127_4771596_4 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000001843 152.0
PYH2_k127_4771596_5 Phage late control gene D protein (GPD) - - - 0.000000000000000000000006341 110.0
PYH2_k127_4790321_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 9.078e-253 788.0
PYH2_k127_4790321_1 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
PYH2_k127_4790321_2 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 289.0
PYH2_k127_4790321_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 256.0
PYH2_k127_4790321_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000002106 188.0
PYH2_k127_4790321_5 Putative zinc-finger - - - 0.000000002576 62.0
PYH2_k127_480809_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.659e-264 818.0
PYH2_k127_480809_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 519.0
PYH2_k127_480809_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 355.0
PYH2_k127_4833479_0 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000134 282.0
PYH2_k127_4833479_1 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000007158 220.0
PYH2_k127_4833479_2 Excisionase - - - 0.00000000007037 64.0
PYH2_k127_4833479_3 MraZ protein, putative antitoxin-like K03925 - - 0.00000001915 55.0
PYH2_k127_4848495_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 332.0
PYH2_k127_4848495_1 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 320.0
PYH2_k127_4848495_2 - - - - 0.0003561 48.0
PYH2_k127_4873485_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 554.0
PYH2_k127_4873485_1 beta-fructofuranosidase activity - - - 0.000000000000000004437 84.0
PYH2_k127_4873773_0 Dehydratase family K01687 - 4.2.1.9 4.882e-278 859.0
PYH2_k127_4873773_1 nitric oxide dioxygenase activity K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 296.0
PYH2_k127_4873773_2 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002194 267.0
PYH2_k127_4873773_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000005245 195.0
PYH2_k127_4873773_4 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000002571 147.0
PYH2_k127_4873773_5 peptidase - - - 0.00000000000000000000000000000002568 129.0
PYH2_k127_4888035_0 GHKL domain K13598 - 2.7.13.3 0.0 1037.0
PYH2_k127_4888035_1 Bacterial regulatory protein, Fis family K13599 - - 1.097e-220 692.0
PYH2_k127_4888035_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000001165 232.0
PYH2_k127_4888035_11 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000001972 164.0
PYH2_k127_4888035_12 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000000000001586 151.0
PYH2_k127_4888035_14 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000357 82.0
PYH2_k127_4888035_15 - - - - 0.0000001389 61.0
PYH2_k127_4888035_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 574.0
PYH2_k127_4888035_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 548.0
PYH2_k127_4888035_4 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 514.0
PYH2_k127_4888035_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 437.0
PYH2_k127_4888035_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 379.0
PYH2_k127_4888035_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 327.0
PYH2_k127_4888035_8 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 314.0
PYH2_k127_4939524_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 523.0
PYH2_k127_4939524_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 349.0
PYH2_k127_4939524_2 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
PYH2_k127_4939524_3 NMT1-like family K02051,K15598 - - 0.000000000000000000000000000000000000000000000002183 187.0
PYH2_k127_4942505_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1529.0
PYH2_k127_4942505_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 404.0
PYH2_k127_4942505_2 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 348.0
PYH2_k127_4942505_3 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000001293 221.0
PYH2_k127_4942505_4 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
PYH2_k127_4942505_5 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001235 185.0
PYH2_k127_4942505_6 - - - - 0.0000000000000000000000000000000000001531 147.0
PYH2_k127_4962044_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 2.654e-223 696.0
PYH2_k127_4962044_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 512.0
PYH2_k127_4962044_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 463.0
PYH2_k127_4962044_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002083 280.0
PYH2_k127_4966924_0 thiamine transport K02011 - - 2.091e-211 666.0
PYH2_k127_4966924_1 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 517.0
PYH2_k127_4966924_2 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007352 260.0
PYH2_k127_4981464_0 phosphorelay signal transduction system K02667 - - 3.655e-224 703.0
PYH2_k127_4981464_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 598.0
PYH2_k127_4981464_10 YGGT family K02221 - - 0.000000000000000000000000000000000002552 151.0
PYH2_k127_4981464_11 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000003512 84.0
PYH2_k127_4981464_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000009335 58.0
PYH2_k127_4981464_2 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 526.0
PYH2_k127_4981464_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 405.0
PYH2_k127_4981464_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 314.0
PYH2_k127_4981464_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005085 276.0
PYH2_k127_4981464_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
PYH2_k127_4981464_7 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000001511 208.0
PYH2_k127_4981464_8 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000009485 160.0
PYH2_k127_5070133_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 609.0
PYH2_k127_5070133_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 566.0
PYH2_k127_5070133_2 tRNA processing K06864,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 319.0
PYH2_k127_5070133_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000547 214.0
PYH2_k127_5070133_4 urea catabolic process K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000237 159.0
PYH2_k127_5070133_5 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000004707 162.0
PYH2_k127_5070133_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000001109 88.0
PYH2_k127_5070133_7 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 GO:0008150,GO:0040007 3.5.1.5 0.0004362 43.0
PYH2_k127_5228999_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.005e-208 653.0
PYH2_k127_5228999_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003507 253.0
PYH2_k127_5228999_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000000000000000000006207 199.0
PYH2_k127_5228999_5 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000001213 172.0
PYH2_k127_5228999_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000002412 151.0
PYH2_k127_5228999_7 Recombinase zinc beta ribbon domain - - - 0.00007865 48.0
PYH2_k127_5240047_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1102.0
PYH2_k127_5240047_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000006849 146.0
PYH2_k127_5240047_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000248 62.0
PYH2_k127_5300202_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 4.125e-212 666.0
PYH2_k127_5300202_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 6.366e-196 614.0
PYH2_k127_5300202_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 490.0
PYH2_k127_5300202_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 342.0
PYH2_k127_5300202_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000003396 143.0
PYH2_k127_5300202_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000002668 142.0
PYH2_k127_5426471_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 601.0
PYH2_k127_5426471_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 594.0
PYH2_k127_5426471_12 Resolvase - - - 0.00025 45.0
PYH2_k127_5426471_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 576.0
PYH2_k127_5426471_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 569.0
PYH2_k127_5426471_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 453.0
PYH2_k127_5426471_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 379.0
PYH2_k127_5426471_6 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000002928 231.0
PYH2_k127_5426471_7 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000000004974 199.0
PYH2_k127_5426471_8 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000005196 172.0
PYH2_k127_5426471_9 CGNR zinc finger - - - 0.000000000000000000000000000000000009809 143.0
PYH2_k127_5447443_0 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 498.0
PYH2_k127_5447443_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 292.0
PYH2_k127_5447443_2 lipoprotein transporter activity K02003 - - 0.00000000000000000000001341 101.0
PYH2_k127_5447443_3 response regulator - - - 0.0000000000000000001237 91.0
PYH2_k127_549214_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 570.0
PYH2_k127_549214_1 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 405.0
PYH2_k127_549214_2 radical SAM domain protein - - - 0.00000000000000000000000007414 107.0
PYH2_k127_549214_3 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.00000000000000000009013 91.0
PYH2_k127_5609144_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1474.0
PYH2_k127_5609144_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1198.0
PYH2_k127_5609144_10 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 411.0
PYH2_k127_5609144_11 pectinesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 409.0
PYH2_k127_5609144_12 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 392.0
PYH2_k127_5609144_13 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 348.0
PYH2_k127_5609144_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 347.0
PYH2_k127_5609144_15 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 336.0
PYH2_k127_5609144_16 Possible lysine decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
PYH2_k127_5609144_17 Histidine kinase K03406 - - 0.00000000000000000000000000000000000000000000000000000000009394 210.0
PYH2_k127_5609144_18 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005089 198.0
PYH2_k127_5609144_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.523e-313 979.0
PYH2_k127_5609144_21 Protein of unknown function (DUF2628) - - - 0.000000000000000000000000002073 116.0
PYH2_k127_5609144_22 IMP dehydrogenase activity K07182 - - 0.00000000000000000000005019 104.0
PYH2_k127_5609144_25 - - - - 0.000000003735 58.0
PYH2_k127_5609144_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 6.411e-254 791.0
PYH2_k127_5609144_4 B3/4 domain K01890 - 6.1.1.20 1.043e-246 773.0
PYH2_k127_5609144_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 512.0
PYH2_k127_5609144_6 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 512.0
PYH2_k127_5609144_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 484.0
PYH2_k127_5609144_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 456.0
PYH2_k127_5609144_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 448.0
PYH2_k127_56532_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5.591e-288 899.0
PYH2_k127_56532_1 Cytochrome b/b6/petB K00412,K03888 - - 5.346e-236 738.0
PYH2_k127_56532_10 - - - - 0.000000000000000000000000000000000000002123 160.0
PYH2_k127_56532_11 S23 ribosomal protein - - - 0.0000000000000000000000000000009528 124.0
PYH2_k127_56532_13 Cytochrome c K12263 - - 0.00000000000000001895 88.0
PYH2_k127_56532_2 Cytochrome c K12263 - - 1.593e-231 724.0
PYH2_k127_56532_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 559.0
PYH2_k127_56532_4 cyclic nucleotide binding K01420,K10914,K21556,K21562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002064 284.0
PYH2_k127_56532_5 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
PYH2_k127_56532_6 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002 252.0
PYH2_k127_56532_7 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000000009612 198.0
PYH2_k127_56532_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000006588 160.0
PYH2_k127_56532_9 integral membrane protein - - - 0.00000000000000000000000000000000000000002225 157.0
PYH2_k127_5662092_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1456.0
PYH2_k127_5662092_1 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1431.0
PYH2_k127_5662092_10 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 343.0
PYH2_k127_5662092_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 337.0
PYH2_k127_5662092_12 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 333.0
PYH2_k127_5662092_13 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000561 284.0
PYH2_k127_5662092_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002145 272.0
PYH2_k127_5662092_15 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000139 275.0
PYH2_k127_5662092_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
PYH2_k127_5662092_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005961 252.0
PYH2_k127_5662092_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
PYH2_k127_5662092_19 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000009563 230.0
PYH2_k127_5662092_2 succinyl-diaminopimelate desuccinylase activity - - - 3.831e-223 698.0
PYH2_k127_5662092_20 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000001332 201.0
PYH2_k127_5662092_21 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000001332 183.0
PYH2_k127_5662092_22 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000002577 173.0
PYH2_k127_5662092_24 - - - - 0.000000000000000000000000000000000000002862 151.0
PYH2_k127_5662092_25 Belongs to the Fur family K09825 - - 0.000000000000000000000008699 106.0
PYH2_k127_5662092_26 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000001521 97.0
PYH2_k127_5662092_28 Domain of unknown function (DUF4410) - - - 0.000000000000002607 86.0
PYH2_k127_5662092_29 - - - - 0.0000000000000092 77.0
PYH2_k127_5662092_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 609.0
PYH2_k127_5662092_30 AntiSigma factor - - - 0.0000000000001701 75.0
PYH2_k127_5662092_32 PFAM Blue (type 1) copper domain - - - 0.00003146 52.0
PYH2_k127_5662092_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 493.0
PYH2_k127_5662092_6 Evidence 2b Function of strongly homologous gene K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 461.0
PYH2_k127_5662092_7 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 428.0
PYH2_k127_5662092_8 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 400.0
PYH2_k127_5662092_9 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 400.0
PYH2_k127_5683736_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 2829.0
PYH2_k127_5683736_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 529.0
PYH2_k127_5683736_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000479 254.0
PYH2_k127_5683736_3 transcription factor binding - - - 0.0000000000000000000002517 99.0
PYH2_k127_5687264_0 Trehalase K03931 - - 5.917e-198 627.0
PYH2_k127_5687264_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
PYH2_k127_5687264_2 metalloendopeptidase activity - - - 0.0000000000000000000000000000000001092 151.0
PYH2_k127_5687264_3 Pfam:DUF303 K05970 - 3.1.1.53 0.000000001879 64.0
PYH2_k127_5698122_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 3.505e-288 896.0
PYH2_k127_5698122_1 membrane K08976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 371.0
PYH2_k127_5724772_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 7.223e-209 654.0
PYH2_k127_5724772_1 Acyl dehydratase - - - 0.000000000000000000000000000000000000002341 164.0
PYH2_k127_5724772_2 KR domain - - - 0.000000000000000000000000000000001617 146.0
PYH2_k127_5747754_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 1.351e-263 845.0
PYH2_k127_5747754_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 7.135e-213 668.0
PYH2_k127_5747754_10 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000006042 220.0
PYH2_k127_5747754_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000001479 223.0
PYH2_k127_5747754_13 Cytochrome c K00406 - - 0.00000000000000000000000000000000000000000000000002606 185.0
PYH2_k127_5747754_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000009971 129.0
PYH2_k127_5747754_17 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.0000000000000000000009851 102.0
PYH2_k127_5747754_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 4.283e-202 652.0
PYH2_k127_5747754_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 524.0
PYH2_k127_5747754_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
PYH2_k127_5747754_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 309.0
PYH2_k127_5747754_6 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
PYH2_k127_5747754_7 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000012 291.0
PYH2_k127_5747754_8 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
PYH2_k127_5747754_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
PYH2_k127_5766725_0 silver ion transport K15726 - - 0.0 1588.0
PYH2_k127_5766725_1 AAA domain - - - 0.0 1089.0
PYH2_k127_5766725_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.00000000000000000000000000000001101 132.0
PYH2_k127_5766725_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000001085 117.0
PYH2_k127_5766725_14 - - - - 0.0000001051 61.0
PYH2_k127_5766725_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1048.0
PYH2_k127_5766725_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 605.0
PYH2_k127_5766725_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 544.0
PYH2_k127_5766725_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 411.0
PYH2_k127_5766725_6 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000001411 246.0
PYH2_k127_5766725_7 regulation of translation K03704,K05809 - - 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
PYH2_k127_5766725_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000003346 198.0
PYH2_k127_5766725_9 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000501 160.0
PYH2_k127_5822261_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 344.0
PYH2_k127_5822261_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000003107 197.0
PYH2_k127_5822261_2 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000001344 162.0
PYH2_k127_5822261_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000001609 153.0
PYH2_k127_5822261_4 ATP synthase delta (OSCP) subunit K02113 - - 0.00000000000000000001558 103.0
PYH2_k127_5822261_5 ATP synthase subunit C K02110 - - 0.00000000000000000003383 91.0
PYH2_k127_5897188_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 578.0
PYH2_k127_5897188_1 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000002706 226.0
PYH2_k127_5897188_2 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.00000000000000000000000000000000000000000000000003645 187.0
PYH2_k127_5897188_3 PFAM IS66 Orf2 family protein K07484 - - 0.000000000000000000000000000000000000000001342 161.0
PYH2_k127_5897188_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000005222 69.0
PYH2_k127_5897188_5 Transposase - - - 0.0000001919 57.0
PYH2_k127_6034454_0 Aminotransferase class I and II K14261 - - 1.73e-232 722.0
PYH2_k127_6034454_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
PYH2_k127_6034454_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000005767 111.0
PYH2_k127_6034454_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000001845 90.0
PYH2_k127_6038911_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 550.0
PYH2_k127_6038911_1 Protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 518.0
PYH2_k127_6038911_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 433.0
PYH2_k127_6038911_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 306.0
PYH2_k127_6038911_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009775 256.0
PYH2_k127_6038911_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000001696 172.0
PYH2_k127_6038911_6 resolution of meiotic recombination intermediates K05516 - - 0.000000000000000000000000000000000005561 140.0
PYH2_k127_6041700_0 alpha-ribazole phosphatase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0 1175.0
PYH2_k127_6041700_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 3.07e-215 685.0
PYH2_k127_6041700_10 SprT-like family K02742 - - 0.00000000000000000000000000000000000000000000000000006411 196.0
PYH2_k127_6041700_11 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000000000000000000000000000000000000399 185.0
PYH2_k127_6041700_13 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000008176 168.0
PYH2_k127_6041700_15 nuclease - - - 0.000000000000000000001076 104.0
PYH2_k127_6041700_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000003924 68.0
PYH2_k127_6041700_2 Aminotransferase class-III K01845 - 5.4.3.8 7.762e-203 639.0
PYH2_k127_6041700_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.63e-200 637.0
PYH2_k127_6041700_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 577.0
PYH2_k127_6041700_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 499.0
PYH2_k127_6041700_6 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 485.0
PYH2_k127_6041700_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 349.0
PYH2_k127_6041700_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 292.0
PYH2_k127_6041700_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006914 254.0
PYH2_k127_6041751_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1076.0
PYH2_k127_6041751_1 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000000001392 137.0
PYH2_k127_6041751_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000003213 106.0
PYH2_k127_6041751_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000001908 70.0
PYH2_k127_6068325_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000002757 232.0
PYH2_k127_6073530_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.621e-215 698.0
PYH2_k127_6073530_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 587.0
PYH2_k127_6073530_2 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 349.0
PYH2_k127_6073530_3 general secretion pathway protein K02456,K02650,K02679,K08084 - - 0.0000000000000000000000000000000002029 143.0
PYH2_k127_6180158_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.443e-237 742.0
PYH2_k127_6180158_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 414.0
PYH2_k127_6180158_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004702 270.0
PYH2_k127_6180158_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000003374 146.0
PYH2_k127_6180158_4 ATP synthase delta (OSCP) subunit K02113 - - 0.00000000000000000001205 103.0
PYH2_k127_6180158_5 ATP synthase subunit C K02110 - - 0.0000000000001549 70.0
PYH2_k127_6208992_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 553.0
PYH2_k127_6208992_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 412.0
PYH2_k127_6208992_2 oxidoreductase activity - - - 0.00000000000005627 72.0
PYH2_k127_6424889_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 4.545e-198 643.0
PYH2_k127_6424889_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 544.0
PYH2_k127_6424889_2 carbamoyl transferase, NodU family K00612,K16035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 488.0
PYH2_k127_6424889_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 426.0
PYH2_k127_6424889_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 356.0
PYH2_k127_6424889_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000004188 197.0
PYH2_k127_6424889_7 lipolytic protein G-D-S-L family - - - 0.000000000004209 78.0
PYH2_k127_6532258_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1044.0
PYH2_k127_6532258_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 578.0
PYH2_k127_6532258_2 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 323.0
PYH2_k127_6532258_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
PYH2_k127_6532258_4 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000001247 127.0
PYH2_k127_6532258_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000005764 130.0
PYH2_k127_6532258_7 - - - - 0.00000009989 53.0
PYH2_k127_6532596_0 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 538.0
PYH2_k127_6540290_0 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000004985 241.0
PYH2_k127_6540290_1 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000000000000001299 202.0
PYH2_k127_6540290_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000006604 136.0
PYH2_k127_6540290_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000001262 123.0
PYH2_k127_6540290_4 Protein of unknown function (DUF507) - - - 0.0000000000000000000000007698 107.0
PYH2_k127_6540290_5 Protein of unknown function (DUF507) - - - 0.0000000000000000000003419 102.0
PYH2_k127_6558435_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 528.0
PYH2_k127_6558435_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003112 281.0
PYH2_k127_6561424_0 Cation transporter/ATPase, N-terminus - - - 0.0 1292.0
PYH2_k127_6561424_1 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 424.0
PYH2_k127_6561424_2 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000003234 204.0
PYH2_k127_6561424_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000006818 106.0
PYH2_k127_6561424_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000001989 65.0
PYH2_k127_6623831_0 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 1.582e-245 767.0
PYH2_k127_6623831_1 tail specific protease K03797 - 3.4.21.102 6.059e-209 659.0
PYH2_k127_6623831_10 ThiS family K03154 - - 0.00000000000000000000649 94.0
PYH2_k127_6623831_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 478.0
PYH2_k127_6623831_3 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 395.0
PYH2_k127_6623831_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 331.0
PYH2_k127_6623831_5 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 308.0
PYH2_k127_6623831_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007688 255.0
PYH2_k127_6623831_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000003223 211.0
PYH2_k127_6623831_8 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000000000000000000000000000000000000000000832 164.0
PYH2_k127_6623831_9 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000000000000009205 144.0
PYH2_k127_6730727_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.617e-306 947.0
PYH2_k127_6730727_1 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 6.148e-282 874.0
PYH2_k127_6730727_10 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 477.0
PYH2_k127_6730727_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 460.0
PYH2_k127_6730727_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 443.0
PYH2_k127_6730727_13 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 424.0
PYH2_k127_6730727_14 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 429.0
PYH2_k127_6730727_15 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 432.0
PYH2_k127_6730727_16 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 405.0
PYH2_k127_6730727_17 Proto-chlorophyllide reductase 57 kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 384.0
PYH2_k127_6730727_18 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 389.0
PYH2_k127_6730727_19 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
PYH2_k127_6730727_2 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 3.455e-219 689.0
PYH2_k127_6730727_20 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 312.0
PYH2_k127_6730727_21 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
PYH2_k127_6730727_22 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 268.0
PYH2_k127_6730727_23 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
PYH2_k127_6730727_25 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000002666 245.0
PYH2_k127_6730727_26 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
PYH2_k127_6730727_27 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000005289 242.0
PYH2_k127_6730727_29 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000000000000000000007893 158.0
PYH2_k127_6730727_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 8.421e-207 651.0
PYH2_k127_6730727_4 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 604.0
PYH2_k127_6730727_5 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 589.0
PYH2_k127_6730727_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 545.0
PYH2_k127_6730727_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 541.0
PYH2_k127_6730727_8 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 527.0
PYH2_k127_6730727_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 502.0
PYH2_k127_6841725_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 505.0
PYH2_k127_6841725_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 496.0
PYH2_k127_6841725_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
PYH2_k127_6841725_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 377.0
PYH2_k127_6841725_4 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 351.0
PYH2_k127_6841725_5 Protein of unknown function DUF47 K02039,K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 319.0
PYH2_k127_6841725_6 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 290.0
PYH2_k127_6841725_7 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002423 270.0
PYH2_k127_6841725_8 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
PYH2_k127_6841725_9 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000009512 208.0
PYH2_k127_6885041_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.292e-233 737.0
PYH2_k127_6885041_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 1.622e-206 660.0
PYH2_k127_6885041_2 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000001374 206.0
PYH2_k127_6885041_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000007752 160.0
PYH2_k127_6885041_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000001353 91.0
PYH2_k127_6905454_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1447.0
PYH2_k127_6905454_1 Rubrerythrin K22405 - 1.6.3.4 0.0 1216.0
PYH2_k127_6905454_10 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 492.0
PYH2_k127_6905454_11 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 459.0
PYH2_k127_6905454_12 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 447.0
PYH2_k127_6905454_13 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 449.0
PYH2_k127_6905454_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 411.0
PYH2_k127_6905454_15 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 337.0
PYH2_k127_6905454_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 296.0
PYH2_k127_6905454_17 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002064 278.0
PYH2_k127_6905454_18 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
PYH2_k127_6905454_19 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
PYH2_k127_6905454_2 helicase activity - - - 0.0 1150.0
PYH2_k127_6905454_20 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008715 255.0
PYH2_k127_6905454_21 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005181 240.0
PYH2_k127_6905454_22 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000002515 236.0
PYH2_k127_6905454_23 acetyltransferase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000005703 214.0
PYH2_k127_6905454_25 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
PYH2_k127_6905454_26 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000001281 135.0
PYH2_k127_6905454_28 phosphorelay signal transduction system - - - 0.0000000000000000000002039 103.0
PYH2_k127_6905454_3 Elongator protein 3, MiaB family, Radical SAM - - - 5.947e-307 945.0
PYH2_k127_6905454_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 7.679e-303 939.0
PYH2_k127_6905454_5 Iron-sulfur cluster-binding domain - - - 1.084e-273 844.0
PYH2_k127_6905454_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 5.73e-232 731.0
PYH2_k127_6905454_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.092e-211 666.0
PYH2_k127_6905454_8 NADH-quinone oxidoreductase K00341 - 1.6.5.3 2.787e-198 624.0
PYH2_k127_6905454_9 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 554.0
PYH2_k127_6972770_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 355.0
PYH2_k127_6972770_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002946 222.0
PYH2_k127_6972770_3 TIGRFAM phage tail protein - - - 0.0000000000000005123 80.0
PYH2_k127_6972770_4 - - - - 0.0000000000102 70.0
PYH2_k127_7128850_0 siderophore transport K02014 - - 0.0 1099.0
PYH2_k127_7128850_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 416.0
PYH2_k127_7128850_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000001583 230.0
PYH2_k127_7128850_11 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000004775 231.0
PYH2_k127_7128850_12 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000002205 219.0
PYH2_k127_7128850_13 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000001015 204.0
PYH2_k127_7128850_15 30S ribosomal protein S23 - - - 0.0000000000000000000000000000000000006387 142.0
PYH2_k127_7128850_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 393.0
PYH2_k127_7128850_3 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 350.0
PYH2_k127_7128850_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
PYH2_k127_7128850_5 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 347.0
PYH2_k127_7128850_6 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 332.0
PYH2_k127_7128850_7 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 341.0
PYH2_k127_7128850_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 295.0
PYH2_k127_7128850_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 277.0
PYH2_k127_7271335_0 von Willebrand factor (vWF) type A domain K02448 - - 1.729e-311 982.0
PYH2_k127_7271335_1 Rieske (2fe-2S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 462.0
PYH2_k127_7271335_2 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 298.0
PYH2_k127_7271335_3 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000005705 252.0
PYH2_k127_7331243_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 512.0
PYH2_k127_7331243_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 295.0
PYH2_k127_7331243_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
PYH2_k127_7331243_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
PYH2_k127_7331243_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
PYH2_k127_7389292_0 Two component signalling adaptor domain K02487,K06596 - - 1.975e-252 793.0
PYH2_k127_7389292_1 nuclear chromosome segregation K02666,K03497,K19622 - - 0.00000000000000000000000000000000000000000000008811 174.0
PYH2_k127_7389292_2 chemotaxis K02659,K03408,K03415,K11524 - - 0.00000000000000000000000004724 114.0
PYH2_k127_7389292_3 PFAM CheW domain protein K03408 - - 0.00004338 53.0
PYH2_k127_7424836_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 312.0
PYH2_k127_7424836_1 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 307.0
PYH2_k127_7424836_2 ATPase activity K02065 - - 0.000000000000000000000000000000000000000000000001626 182.0
PYH2_k127_7424836_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000002536 163.0
PYH2_k127_7473442_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 415.0
PYH2_k127_7473442_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000000001628 229.0
PYH2_k127_7485395_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1849.0
PYH2_k127_7485395_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1688.0
PYH2_k127_7485395_10 elongation factor Tu domain 2 protein K02355 - - 6.858e-210 674.0
PYH2_k127_7485395_11 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.46e-204 663.0
PYH2_k127_7485395_12 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.91e-201 633.0
PYH2_k127_7485395_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 1.062e-195 619.0
PYH2_k127_7485395_14 serine-type endopeptidase activity K04771 - 3.4.21.107 1.149e-195 619.0
PYH2_k127_7485395_15 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 606.0
PYH2_k127_7485395_16 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 575.0
PYH2_k127_7485395_17 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 545.0
PYH2_k127_7485395_18 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 515.0
PYH2_k127_7485395_19 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 491.0
PYH2_k127_7485395_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0 1360.0
PYH2_k127_7485395_20 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 447.0
PYH2_k127_7485395_21 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 421.0
PYH2_k127_7485395_22 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 413.0
PYH2_k127_7485395_23 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 398.0
PYH2_k127_7485395_24 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 402.0
PYH2_k127_7485395_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 378.0
PYH2_k127_7485395_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 340.0
PYH2_k127_7485395_27 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 328.0
PYH2_k127_7485395_28 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 323.0
PYH2_k127_7485395_29 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
PYH2_k127_7485395_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.91e-321 990.0
PYH2_k127_7485395_30 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 301.0
PYH2_k127_7485395_31 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007696 285.0
PYH2_k127_7485395_32 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004702 270.0
PYH2_k127_7485395_33 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
PYH2_k127_7485395_34 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
PYH2_k127_7485395_35 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003141 244.0
PYH2_k127_7485395_36 protein homooligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000005515 254.0
PYH2_k127_7485395_37 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001973 232.0
PYH2_k127_7485395_38 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000005553 233.0
PYH2_k127_7485395_39 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000664 231.0
PYH2_k127_7485395_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.175e-310 959.0
PYH2_k127_7485395_40 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH2_k127_7485395_41 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000005761 219.0
PYH2_k127_7485395_42 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000005362 213.0
PYH2_k127_7485395_43 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000005998 201.0
PYH2_k127_7485395_44 - - - - 0.000000000000000000000000000000000000000000000000000003584 209.0
PYH2_k127_7485395_45 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000002969 190.0
PYH2_k127_7485395_46 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000000001156 183.0
PYH2_k127_7485395_47 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.00000000000000000000000000000000000000000000002362 190.0
PYH2_k127_7485395_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 5.37e-297 915.0
PYH2_k127_7485395_50 domain protein K10716 - - 0.000000000000000000000000000000000005386 146.0
PYH2_k127_7485395_51 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000009812 141.0
PYH2_k127_7485395_53 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000000000000001473 124.0
PYH2_k127_7485395_54 - - - - 0.000000000000000000000000008898 110.0
PYH2_k127_7485395_55 Putative regulatory protein - - - 0.00000000000000000000000009205 111.0
PYH2_k127_7485395_56 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000003884 108.0
PYH2_k127_7485395_58 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000001326 85.0
PYH2_k127_7485395_59 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000000003496 89.0
PYH2_k127_7485395_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 5.54e-229 716.0
PYH2_k127_7485395_60 Helix-turn-helix domain - - - 0.000000000000002053 80.0
PYH2_k127_7485395_63 - - - - 0.0000000000001454 85.0
PYH2_k127_7485395_65 - - - - 0.00001155 48.0
PYH2_k127_7485395_7 glucan 1,4-alpha-glucosidase activity - - - 3.494e-228 724.0
PYH2_k127_7485395_8 methyltransferase - - - 2.279e-224 721.0
PYH2_k127_7485395_9 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 3.188e-223 699.0
PYH2_k127_7490419_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2690.0
PYH2_k127_7490419_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 8.152e-287 883.0
PYH2_k127_7490419_10 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.00000006132 53.0
PYH2_k127_7490419_2 ATPase activity - - - 1.15e-203 644.0
PYH2_k127_7490419_3 phosphorelay signal transduction system - - - 3.074e-195 622.0
PYH2_k127_7490419_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 562.0
PYH2_k127_7490419_5 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 506.0
PYH2_k127_7490419_6 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 412.0
PYH2_k127_7490419_7 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 412.0
PYH2_k127_7490419_8 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000000000000000000000000000001107 181.0
PYH2_k127_7490419_9 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000007433 175.0
PYH2_k127_7491681_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 6.595e-199 638.0
PYH2_k127_7491681_1 GDSL-like Lipase/Acylhydrolase family K01181,K01187,K06889 - 3.2.1.20,3.2.1.8 0.000000000000000000000001253 120.0
PYH2_k127_7508291_0 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 527.0
PYH2_k127_7508291_1 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 498.0
PYH2_k127_7508291_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 463.0
PYH2_k127_7508291_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 328.0
PYH2_k127_7508291_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 316.0
PYH2_k127_7508291_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004107 287.0
PYH2_k127_7508291_6 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000000000009779 181.0
PYH2_k127_7508291_7 PFAM Glycosyl transferase, group 1 - - - 0.0004561 52.0
PYH2_k127_7527245_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.543e-286 892.0
PYH2_k127_7527245_1 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 381.0
PYH2_k127_7527245_11 - - - - 0.0000000000000001087 89.0
PYH2_k127_7527245_12 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000002279 78.0
PYH2_k127_7527245_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 344.0
PYH2_k127_7527245_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002573 279.0
PYH2_k127_7527245_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002664 268.0
PYH2_k127_7527245_5 phosphonoacetaldehyde hydrolase activity K01091,K07025,K19270 - 3.1.3.18,3.1.3.23 0.000000000000000000000000000000000000000000000000000000000000004328 225.0
PYH2_k127_7527245_6 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000005376 207.0
PYH2_k127_7527245_7 - - - - 0.0000000000000000000000000000000000000000000002554 172.0
PYH2_k127_7527245_8 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000002443 150.0
PYH2_k127_7527245_9 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000003385 108.0
PYH2_k127_7537826_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.3e-220 694.0
PYH2_k127_7537826_1 spermidine synthase activity K00797 - 2.5.1.16 8.921e-210 665.0
PYH2_k127_7537826_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000000000000259 167.0
PYH2_k127_7537826_11 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000005748 166.0
PYH2_k127_7537826_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 469.0
PYH2_k127_7537826_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 422.0
PYH2_k127_7537826_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 379.0
PYH2_k127_7537826_5 branched-chain-amino-acid transaminase activity K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 370.0
PYH2_k127_7537826_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003411 235.0
PYH2_k127_7537826_8 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000006817 182.0
PYH2_k127_7537826_9 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000001273 169.0
PYH2_k127_7542438_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1175.0
PYH2_k127_7542438_1 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 488.0
PYH2_k127_7542438_10 DUF167 K09131 - - 0.00000000000000000002421 93.0
PYH2_k127_7542438_11 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000008951 98.0
PYH2_k127_7542438_12 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000003016 79.0
PYH2_k127_7542438_2 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 479.0
PYH2_k127_7542438_3 Associated with various cellular activities K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 456.0
PYH2_k127_7542438_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
PYH2_k127_7542438_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001706 286.0
PYH2_k127_7542438_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001399 258.0
PYH2_k127_7542438_7 - - - - 0.000000000000000000000000000000000000000000000002108 177.0
PYH2_k127_7542438_9 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000001898 148.0
PYH2_k127_7549257_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.3e-254 790.0
PYH2_k127_7549257_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.33e-227 709.0
PYH2_k127_7549257_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000001537 110.0
PYH2_k127_7549257_11 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000002801 94.0
PYH2_k127_7549257_13 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000002899 87.0
PYH2_k127_7549257_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.093e-225 713.0
PYH2_k127_7549257_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.679e-209 661.0
PYH2_k127_7549257_4 Acts as a magnesium transporter K06213 - - 1.791e-205 649.0
PYH2_k127_7549257_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 390.0
PYH2_k127_7549257_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 286.0
PYH2_k127_7549257_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000003404 216.0
PYH2_k127_7549257_8 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000002738 212.0
PYH2_k127_7549257_9 Bacterial protein of unknown function (DUF948) - - - 0.0000000000000000000000000000000212 131.0
PYH2_k127_7568327_0 glycoside hydrolase family 2 sugar binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002963 290.0
PYH2_k127_7600165_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 376.0
PYH2_k127_7600165_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
PYH2_k127_7600165_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
PYH2_k127_7600165_4 Regulatory protein, FmdB family - - - 0.0000000000000000000000000005583 115.0
PYH2_k127_7616556_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000001208 206.0
PYH2_k127_7616556_3 Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000002845 211.0
PYH2_k127_7616556_4 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000001089 193.0
PYH2_k127_7616556_5 phosphorelay sensor kinase activity K02038,K02282,K07018,K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000005855 194.0
PYH2_k127_7624255_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000004647 158.0
PYH2_k127_7624255_2 Tetratricopeptide repeat - - - 0.0000000000000000001371 100.0
PYH2_k127_7624255_3 FecR protein - - - 0.0000000003796 70.0
PYH2_k127_7660716_0 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 537.0
PYH2_k127_7660716_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 419.0
PYH2_k127_7660716_2 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 404.0
PYH2_k127_7660716_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 390.0
PYH2_k127_7660716_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
PYH2_k127_7660716_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000003407 138.0
PYH2_k127_7660716_6 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000000000000002969 117.0
PYH2_k127_7686252_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1159.0
PYH2_k127_7686252_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003942 259.0
PYH2_k127_7708596_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 332.0
PYH2_k127_7708596_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000229 267.0
PYH2_k127_7708596_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001446 237.0
PYH2_k127_7708596_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000286 217.0
PYH2_k127_7708596_4 PFAM OmpA MotB domain protein K02557 - - 0.000000000000002739 89.0
PYH2_k127_7708596_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000002976 66.0
PYH2_k127_7760788_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1487.0
PYH2_k127_7760788_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1281.0
PYH2_k127_7760788_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 501.0
PYH2_k127_7760788_11 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 488.0
PYH2_k127_7760788_12 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 496.0
PYH2_k127_7760788_13 ATPase activity K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 478.0
PYH2_k127_7760788_14 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 464.0
PYH2_k127_7760788_15 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 432.0
PYH2_k127_7760788_16 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 412.0
PYH2_k127_7760788_17 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 401.0
PYH2_k127_7760788_18 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 350.0
PYH2_k127_7760788_19 Evidence 2b Function of strongly homologous gene K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 333.0
PYH2_k127_7760788_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.651e-318 984.0
PYH2_k127_7760788_20 cellular water homeostasis K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 328.0
PYH2_k127_7760788_21 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
PYH2_k127_7760788_22 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 290.0
PYH2_k127_7760788_23 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 300.0
PYH2_k127_7760788_24 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 283.0
PYH2_k127_7760788_25 FMN binding K19339,K19343 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001276 281.0
PYH2_k127_7760788_29 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007383 239.0
PYH2_k127_7760788_3 thiamine transport K02011 - - 5.491e-231 730.0
PYH2_k127_7760788_30 bacteriocin transport K03561,K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000863 224.0
PYH2_k127_7760788_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000006118 225.0
PYH2_k127_7760788_32 - - - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
PYH2_k127_7760788_33 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000001862 211.0
PYH2_k127_7760788_34 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000002412 168.0
PYH2_k127_7760788_35 GGDEF domain - - - 0.0000000000000000000000000000000000000000000002755 170.0
PYH2_k127_7760788_36 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.0000000000000000000000000000000000000000000279 173.0
PYH2_k127_7760788_37 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000003965 160.0
PYH2_k127_7760788_39 energy transducer activity K03832 - - 0.0000000000000000000000000000002668 134.0
PYH2_k127_7760788_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 4.659e-210 658.0
PYH2_k127_7760788_40 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000002451 89.0
PYH2_k127_7760788_41 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000009996 70.0
PYH2_k127_7760788_43 - - - - 0.00003002 48.0
PYH2_k127_7760788_44 Helix-hairpin-helix motif - - - 0.00004194 54.0
PYH2_k127_7760788_5 MacB-like periplasmic core domain K02004 - - 4.454e-205 644.0
PYH2_k127_7760788_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 558.0
PYH2_k127_7760788_7 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 560.0
PYH2_k127_7760788_8 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 555.0
PYH2_k127_7760788_9 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 520.0
PYH2_k127_7789256_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 4.183e-234 733.0
PYH2_k127_7924907_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 377.0
PYH2_k127_7924907_1 PFAM Sodium hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 324.0
PYH2_k127_7924907_2 - - - - 0.00000000000000000000000004594 117.0
PYH2_k127_7943382_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 511.0
PYH2_k127_7943382_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 277.0
PYH2_k127_7943382_2 Type II secretory pathway component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001656 269.0
PYH2_k127_7943382_3 RNA recognition motif - - - 0.0000000000000000000000000000000000000000006535 158.0
PYH2_k127_7943382_4 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000000000000000000000004658 162.0
PYH2_k127_7943382_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000001647 162.0
PYH2_k127_7943382_6 modulation by symbiont of host adenylate cyclase-mediated signal transduction K03775 - 5.2.1.8 0.0000000000000000000000000000000000000001682 155.0
PYH2_k127_7943382_7 paraquat-inducible protein b K06192 - - 0.000000000004607 66.0
PYH2_k127_7952402_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1835.0
PYH2_k127_7952402_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.84e-216 687.0
PYH2_k127_7952402_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 549.0
PYH2_k127_7952402_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 508.0
PYH2_k127_7952402_6 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000003617 136.0
PYH2_k127_8010926_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000142 222.0
PYH2_k127_8010926_1 Bacterial protein of unknown function (DUF885) - - - 0.000007835 51.0
PYH2_k127_8038433_0 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 6.547e-275 857.0
PYH2_k127_8038433_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.574e-204 640.0
PYH2_k127_8038433_2 ATPase activity K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000005613 194.0
PYH2_k127_8038433_3 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000008976 92.0
PYH2_k127_8068666_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 1.673e-257 803.0
PYH2_k127_8068666_1 Domain of unknown function (DUF4105) - - - 2.978e-251 791.0
PYH2_k127_8068666_10 uroporphyrinogen-III synthase activity K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 327.0
PYH2_k127_8068666_11 Lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 305.0
PYH2_k127_8068666_12 antisigma factor binding K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 287.0
PYH2_k127_8068666_13 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
PYH2_k127_8068666_14 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000000001047 176.0
PYH2_k127_8068666_15 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000001049 150.0
PYH2_k127_8068666_16 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000001699 155.0
PYH2_k127_8068666_17 Lipoprotein - - - 0.000000000000000000000000000003301 130.0
PYH2_k127_8068666_18 23S rRNA-intervening sequence protein - - - 0.0000000000000003735 81.0
PYH2_k127_8068666_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 582.0
PYH2_k127_8068666_20 Putative nucleotidyltransferase substrate binding domain - - - 0.0007787 50.0
PYH2_k127_8068666_3 alcohol dehydrogenase K00060,K07777 - 1.1.1.103,2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 563.0
PYH2_k127_8068666_4 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 555.0
PYH2_k127_8068666_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 506.0
PYH2_k127_8068666_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 421.0
PYH2_k127_8068666_7 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 422.0
PYH2_k127_8068666_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 371.0
PYH2_k127_8068666_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 329.0
PYH2_k127_8141437_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0 1248.0
PYH2_k127_8141437_1 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 514.0
PYH2_k127_8141437_10 response regulator K03413 - - 0.000000000000000000000000001653 114.0
PYH2_k127_8141437_11 protein transport across the cell outer membrane K02457,K02672,K08084,K08085 - - 0.000000000000000000000000822 109.0
PYH2_k127_8141437_12 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.000000000000000000006852 99.0
PYH2_k127_8141437_13 protein transport across the cell outer membrane - - - 0.000000000005782 73.0
PYH2_k127_8141437_2 Pilus assembly protein PilX K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 387.0
PYH2_k127_8141437_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 351.0
PYH2_k127_8141437_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 270.0
PYH2_k127_8141437_5 self proteolysis - - - 0.000000000000000000000000000000000000000000000000000000008633 215.0
PYH2_k127_8141437_6 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000000000000000000000000003117 195.0
PYH2_k127_8141437_7 pilus assembly protein PilW K02672 - - 0.00000000000000000000000000000000000003068 160.0
PYH2_k127_8141437_8 Putative Competence protein ComGF K02246,K02248 - - 0.000000000000000000000000000001943 131.0
PYH2_k127_8148920_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 463.0
PYH2_k127_8148920_1 NUBPL iron-transfer P-loop NTPase K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 452.0
PYH2_k127_8148920_10 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000002179 216.0
PYH2_k127_8148920_11 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000507 204.0
PYH2_k127_8148920_12 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000001994 194.0
PYH2_k127_8148920_13 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000001412 170.0
PYH2_k127_8148920_14 PFAM methyltransferase - - - 0.00000000000000000000000000000000000003719 157.0
PYH2_k127_8148920_15 methyltransferase K16648 - - 0.000000000000000000000000000000000002874 147.0
PYH2_k127_8148920_17 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.000000000000000000000000000007086 134.0
PYH2_k127_8148920_18 Glycosyltransferase Family 4 - - - 0.000000000000000000000000003368 126.0
PYH2_k127_8148920_19 Glycosyl transferase, family 2 - - - 0.00000000000000000000000001604 120.0
PYH2_k127_8148920_2 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
PYH2_k127_8148920_20 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000002858 118.0
PYH2_k127_8148920_21 Polysaccharide biosynthesis protein - - - 0.0000000000000000000008179 109.0
PYH2_k127_8148920_22 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.000000000000000572 90.0
PYH2_k127_8148920_23 Methionine biosynthesis protein MetW - - - 0.000000000000006673 87.0
PYH2_k127_8148920_24 Glycosyltransferase family 87 K13671 - - 0.000000000006708 78.0
PYH2_k127_8148920_25 PFAM Polysaccharide export protein K01991 - - 0.000000009136 66.0
PYH2_k127_8148920_26 Glycosyltransferase family 87 K13671 - - 0.0000004701 63.0
PYH2_k127_8148920_3 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
PYH2_k127_8148920_4 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 338.0
PYH2_k127_8148920_5 O-Antigen Polymerase K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 304.0
PYH2_k127_8148920_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 291.0
PYH2_k127_8148920_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001534 242.0
PYH2_k127_8148920_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000004145 222.0
PYH2_k127_8148920_9 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002636 222.0
PYH2_k127_8259834_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.971e-288 898.0
PYH2_k127_8259834_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 559.0
PYH2_k127_8259834_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 392.0
PYH2_k127_8259834_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 295.0
PYH2_k127_8259834_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009067 253.0
PYH2_k127_8259834_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000001101 229.0
PYH2_k127_8452600_0 radical SAM domain protein - - - 1.235e-315 974.0
PYH2_k127_8452600_1 NHL repeat - - - 7.295e-241 747.0
PYH2_k127_8452600_2 denitrification pathway - - - 7.512e-209 657.0
PYH2_k127_8452600_3 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 454.0
PYH2_k127_8452600_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 428.0
PYH2_k127_8452600_6 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 337.0
PYH2_k127_8452600_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000001385 103.0
PYH2_k127_8452600_9 denitrification pathway - - - 0.000000001513 64.0
PYH2_k127_8455262_0 Glycosyl hydrolase family 57 - - - 9.649e-305 949.0
PYH2_k127_8455262_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 564.0
PYH2_k127_8455262_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 473.0
PYH2_k127_8455262_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 457.0
PYH2_k127_8455262_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 340.0
PYH2_k127_8460406_0 Nucleotidyltransferase DNA polymerase involved in DNA repair K03502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 434.0
PYH2_k127_8460406_1 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000000000000000000001572 184.0
PYH2_k127_8460406_2 lipid binding - - - 0.0000000000000000000000000000000001147 136.0
PYH2_k127_8500297_0 PP-loop family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 475.0
PYH2_k127_8500297_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.00000000000000000000000000000000000000000006402 164.0
PYH2_k127_8500297_2 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000319 103.0
PYH2_k127_8500297_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000002913 63.0
PYH2_k127_8523542_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 430.0
PYH2_k127_8523542_1 - - - - 0.000000000000000000000000000000000000000000003222 168.0
PYH2_k127_8523542_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000004683 110.0
PYH2_k127_8574169_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001723 249.0
PYH2_k127_8574169_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000003999 136.0
PYH2_k127_85985_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.974e-250 788.0
PYH2_k127_85985_1 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 531.0
PYH2_k127_85985_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000008817 98.0
PYH2_k127_85985_3 FecR protein - - - 0.00002221 51.0
PYH2_k127_8610281_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 7.459e-222 693.0
PYH2_k127_8610281_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 470.0
PYH2_k127_8610281_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001822 246.0
PYH2_k127_8610281_3 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000004485 223.0
PYH2_k127_8616566_0 arabinan catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 304.0
PYH2_k127_8616566_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000018 102.0
PYH2_k127_8621626_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 398.0
PYH2_k127_8621626_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 289.0
PYH2_k127_8621626_2 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
PYH2_k127_8621626_3 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000575 143.0
PYH2_k127_8622353_0 radical SAM domain protein - - - 0.0 1021.0
PYH2_k127_8622353_1 radical SAM domain protein - - - 0.0 1017.0
PYH2_k127_8622353_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 424.0
PYH2_k127_8622353_11 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 414.0
PYH2_k127_8622353_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 384.0
PYH2_k127_8622353_13 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 376.0
PYH2_k127_8622353_14 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
PYH2_k127_8622353_15 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 362.0
PYH2_k127_8622353_16 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 352.0
PYH2_k127_8622353_18 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 303.0
PYH2_k127_8622353_19 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 258.0
PYH2_k127_8622353_2 radical SAM domain protein - - - 4.516e-222 692.0
PYH2_k127_8622353_20 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004059 257.0
PYH2_k127_8622353_21 PFAM AIG2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009323 253.0
PYH2_k127_8622353_22 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 255.0
PYH2_k127_8622353_23 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002886 241.0
PYH2_k127_8622353_24 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000007723 209.0
PYH2_k127_8622353_25 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000004343 213.0
PYH2_k127_8622353_26 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000006704 202.0
PYH2_k127_8622353_27 cytochrome complex assembly K02200,K04018,K19225,K20543,K21007 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000006149 201.0
PYH2_k127_8622353_28 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000001579 202.0
PYH2_k127_8622353_29 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000001877 196.0
PYH2_k127_8622353_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 4.24e-221 696.0
PYH2_k127_8622353_30 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000005047 190.0
PYH2_k127_8622353_31 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000000003123 172.0
PYH2_k127_8622353_32 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000487 173.0
PYH2_k127_8622353_33 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000001765 168.0
PYH2_k127_8622353_34 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000001806 147.0
PYH2_k127_8622353_35 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000002762 139.0
PYH2_k127_8622353_37 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000001437 126.0
PYH2_k127_8622353_38 Sulfurtransferase TusA - - - 0.0000000000000000000000000001564 117.0
PYH2_k127_8622353_39 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000001942 83.0
PYH2_k127_8622353_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 613.0
PYH2_k127_8622353_5 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 524.0
PYH2_k127_8622353_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 514.0
PYH2_k127_8622353_7 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 473.0
PYH2_k127_8622353_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 475.0
PYH2_k127_8622353_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 448.0
PYH2_k127_8626793_0 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 457.0
PYH2_k127_8626793_1 nucleotidyltransferase activity K17882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
PYH2_k127_8626793_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 276.0
PYH2_k127_8626793_4 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000001879 123.0
PYH2_k127_8626793_6 sequence-specific DNA binding - - - 0.000000000000000000000000005198 111.0
PYH2_k127_8654364_0 protein secretion by the type I secretion system K02021 - - 2.548e-216 685.0
PYH2_k127_8654364_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 464.0
PYH2_k127_8654364_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 327.0
PYH2_k127_8654364_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002768 261.0
PYH2_k127_8654364_4 Late embryogenesis abundant protein - - - 0.0000006521 59.0
PYH2_k127_8665420_0 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 543.0
PYH2_k127_8665420_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 446.0
PYH2_k127_8665420_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
PYH2_k127_8665420_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007538 274.0
PYH2_k127_8665420_4 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002492 248.0
PYH2_k127_8665420_5 - - - - 0.000000000000000000000000000000000000000000000000000000000003832 209.0
PYH2_k127_8665420_6 transmembrane transporter activity K03535 - - 0.000000000000000000000000000000000000002072 150.0
PYH2_k127_8681745_0 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 2.075e-245 769.0
PYH2_k127_8681745_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 2.287e-212 663.0
PYH2_k127_8681745_10 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 449.0
PYH2_k127_8681745_11 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 429.0
PYH2_k127_8681745_12 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
PYH2_k127_8681745_13 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 398.0
PYH2_k127_8681745_14 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 374.0
PYH2_k127_8681745_15 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 319.0
PYH2_k127_8681745_16 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 302.0
PYH2_k127_8681745_17 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 296.0
PYH2_k127_8681745_18 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 285.0
PYH2_k127_8681745_19 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000006817 260.0
PYH2_k127_8681745_2 methyltransferase K07755 - 2.1.1.137 1.371e-199 627.0
PYH2_k127_8681745_20 protein disulfide oxidoreductase activity K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000001626 198.0
PYH2_k127_8681745_21 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000002018 215.0
PYH2_k127_8681745_22 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000001996 175.0
PYH2_k127_8681745_25 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000000000000000000000003359 130.0
PYH2_k127_8681745_26 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000000000000000000000435 120.0
PYH2_k127_8681745_27 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000004346 115.0
PYH2_k127_8681745_28 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000000000000000000005179 123.0
PYH2_k127_8681745_29 Histidine kinase K03406 - - 0.0000000000000000000000009758 121.0
PYH2_k127_8681745_3 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 609.0
PYH2_k127_8681745_30 Belongs to the BolA IbaG family K05527,K22066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000001163 103.0
PYH2_k127_8681745_4 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 623.0
PYH2_k127_8681745_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 606.0
PYH2_k127_8681745_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 602.0
PYH2_k127_8681745_7 stress-induced mitochondrial fusion K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 492.0
PYH2_k127_8681745_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 494.0
PYH2_k127_8681745_9 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 457.0
PYH2_k127_8723799_0 radical SAM domain protein - - - 2.205e-225 709.0
PYH2_k127_8738605_0 AcrB/AcrD/AcrF family - - - 0.0 1660.0
PYH2_k127_8738605_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1015.0
PYH2_k127_8738605_10 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 475.0
PYH2_k127_8738605_11 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 471.0
PYH2_k127_8738605_12 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 423.0
PYH2_k127_8738605_13 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 407.0
PYH2_k127_8738605_14 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
PYH2_k127_8738605_15 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 374.0
PYH2_k127_8738605_16 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
PYH2_k127_8738605_17 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 343.0
PYH2_k127_8738605_18 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
PYH2_k127_8738605_19 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 316.0
PYH2_k127_8738605_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.911e-255 797.0
PYH2_k127_8738605_20 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
PYH2_k127_8738605_21 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000126 259.0
PYH2_k127_8738605_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 245.0
PYH2_k127_8738605_23 Cytochrome c K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000006681 236.0
PYH2_k127_8738605_24 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000001711 221.0
PYH2_k127_8738605_29 Lipoprotein - - - 0.00000000000000000000000000000004962 138.0
PYH2_k127_8738605_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 4.211e-204 648.0
PYH2_k127_8738605_32 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000248 119.0
PYH2_k127_8738605_34 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000005611 107.0
PYH2_k127_8738605_36 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000003854 78.0
PYH2_k127_8738605_38 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.000002199 53.0
PYH2_k127_8738605_4 TIGRFAM phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 597.0
PYH2_k127_8738605_5 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 553.0
PYH2_k127_8738605_6 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 535.0
PYH2_k127_8738605_7 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 526.0
PYH2_k127_8738605_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 536.0
PYH2_k127_8743931_0 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 390.0
PYH2_k127_8743931_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 282.0
PYH2_k127_8743931_2 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000000000000000000000000001684 185.0
PYH2_k127_8749111_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.893e-251 784.0
PYH2_k127_8749111_1 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 1.089e-208 660.0
PYH2_k127_8749111_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000004314 221.0
PYH2_k127_8749111_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000116 206.0
PYH2_k127_8749111_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.0000000000000000000000000000000000000000000000000000000004311 205.0
PYH2_k127_8749111_13 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000003355 205.0
PYH2_k127_8749111_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000002301 175.0
PYH2_k127_8749111_15 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000001495 112.0
PYH2_k127_8749111_17 - - - - 0.00000000000000008766 82.0
PYH2_k127_8749111_19 PFAM SH3, type 3 - - - 0.000000000004532 79.0
PYH2_k127_8749111_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 412.0
PYH2_k127_8749111_3 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 337.0
PYH2_k127_8749111_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003132 285.0
PYH2_k127_8749111_5 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006581 294.0
PYH2_k127_8749111_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006633 273.0
PYH2_k127_8749111_7 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001086 273.0
PYH2_k127_8749111_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000001189 232.0
PYH2_k127_8749111_9 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
PYH2_k127_8806734_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 484.0
PYH2_k127_8912873_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1094.0
PYH2_k127_8912873_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1019.0
PYH2_k127_8912873_10 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 332.0
PYH2_k127_8912873_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000006277 186.0
PYH2_k127_8912873_14 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000003373 164.0
PYH2_k127_8912873_15 peptidoglycan binding K03642 - - 0.000000000000000000000000000000000000000002135 163.0
PYH2_k127_8912873_17 transcription factor binding - - - 0.0000000000000000000000000008406 123.0
PYH2_k127_8912873_18 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001611 113.0
PYH2_k127_8912873_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.461e-320 996.0
PYH2_k127_8912873_20 - - - - 0.0000000000000001945 85.0
PYH2_k127_8912873_21 - - - - 0.0000000003249 69.0
PYH2_k127_8912873_23 Phosphate starvation-inducible protein, PSIF - - - 0.000001773 55.0
PYH2_k127_8912873_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000002438 49.0
PYH2_k127_8912873_25 PilZ domain - - - 0.000007319 55.0
PYH2_k127_8912873_3 - K01992 - - 6.378e-194 617.0
PYH2_k127_8912873_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 481.0
PYH2_k127_8912873_6 ATPase activity K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 469.0
PYH2_k127_8912873_7 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 404.0
PYH2_k127_8912873_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 376.0
PYH2_k127_8912873_9 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 348.0
PYH2_k127_892231_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 497.0
PYH2_k127_892231_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 408.0
PYH2_k127_8980771_0 Protein of unknown function, DUF255 K06888 - - 0.0 1616.0
PYH2_k127_8980771_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1431.0
PYH2_k127_8980771_10 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 473.0
PYH2_k127_8980771_11 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 466.0
PYH2_k127_8980771_12 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 447.0
PYH2_k127_8980771_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 422.0
PYH2_k127_8980771_14 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 389.0
PYH2_k127_8980771_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 351.0
PYH2_k127_8980771_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 322.0
PYH2_k127_8980771_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 312.0
PYH2_k127_8980771_18 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 298.0
PYH2_k127_8980771_19 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 292.0
PYH2_k127_8980771_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.416e-246 768.0
PYH2_k127_8980771_20 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003772 266.0
PYH2_k127_8980771_21 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 257.0
PYH2_k127_8980771_22 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001089 251.0
PYH2_k127_8980771_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000003704 228.0
PYH2_k127_8980771_24 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
PYH2_k127_8980771_25 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000001824 203.0
PYH2_k127_8980771_26 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000522 191.0
PYH2_k127_8980771_28 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000001181 181.0
PYH2_k127_8980771_29 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000001425 169.0
PYH2_k127_8980771_3 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.656e-234 731.0
PYH2_k127_8980771_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000000000003752 161.0
PYH2_k127_8980771_32 - - - - 0.00000000000000000000000000000005046 128.0
PYH2_k127_8980771_34 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000001793 128.0
PYH2_k127_8980771_35 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000005057 129.0
PYH2_k127_8980771_4 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 3.888e-195 614.0
PYH2_k127_8980771_5 xylulokinase activity K00854 - 2.7.1.17 1.279e-194 615.0
PYH2_k127_8980771_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 606.0
PYH2_k127_8980771_7 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 571.0
PYH2_k127_8980771_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 559.0
PYH2_k127_8980771_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 496.0
PYH2_k127_9043021_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 2836.0
PYH2_k127_9043021_1 amino acid - - - 3.826e-290 900.0
PYH2_k127_9043021_2 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 500.0
PYH2_k127_9043021_4 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 413.0
PYH2_k127_9043021_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 400.0
PYH2_k127_9043021_6 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 374.0
PYH2_k127_9043021_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 359.0
PYH2_k127_9043021_8 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.0000000000001373 71.0
PYH2_k127_9101102_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 578.0
PYH2_k127_9101102_1 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000000000000001706 164.0
PYH2_k127_912669_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1375.0
PYH2_k127_912669_1 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0 1086.0
PYH2_k127_912669_10 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006898 276.0
PYH2_k127_912669_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000001061 241.0
PYH2_k127_912669_12 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002069 227.0
PYH2_k127_912669_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000000002798 185.0
PYH2_k127_912669_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000004592 150.0
PYH2_k127_912669_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000007718 106.0
PYH2_k127_912669_16 - - - - 0.0000000000000000003711 92.0
PYH2_k127_912669_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 3.209e-275 852.0
PYH2_k127_912669_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.328e-240 751.0
PYH2_k127_912669_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 5.775e-239 752.0
PYH2_k127_912669_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 4.445e-214 665.0
PYH2_k127_912669_6 Sigma-54 interaction domain K07714 - - 1.474e-213 671.0
PYH2_k127_912669_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 336.0
PYH2_k127_912669_8 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 295.0
PYH2_k127_912669_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 304.0
PYH2_k127_9130460_0 - - - - 9.015e-270 841.0
PYH2_k127_9130460_1 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 443.0
PYH2_k127_9130460_2 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 334.0
PYH2_k127_9130460_3 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005442 283.0
PYH2_k127_9130460_4 tungstate binding K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 265.0
PYH2_k127_9130460_6 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000001107 160.0
PYH2_k127_9169366_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 553.0
PYH2_k127_9169366_1 response regulator - - - 0.0000000000000000000000000000000003672 138.0
PYH2_k127_9169366_2 resolution of meiotic recombination intermediates K05516 - - 0.00000000000000006736 80.0
PYH2_k127_9190505_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 598.0
PYH2_k127_9190505_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
PYH2_k127_9190505_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000076 259.0
PYH2_k127_9190505_3 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000001911 136.0
PYH2_k127_9220013_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 460.0
PYH2_k127_9220013_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 413.0
PYH2_k127_9220013_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 305.0
PYH2_k127_9234947_0 Putative modulator of DNA gyrase K03568 - - 1.538e-250 779.0
PYH2_k127_9234947_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.517e-215 683.0
PYH2_k127_9234947_10 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 345.0
PYH2_k127_9234947_11 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 333.0
PYH2_k127_9234947_12 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 311.0
PYH2_k127_9234947_13 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 300.0
PYH2_k127_9234947_14 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001315 289.0
PYH2_k127_9234947_15 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000105 263.0
PYH2_k127_9234947_16 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003339 280.0
PYH2_k127_9234947_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 244.0
PYH2_k127_9234947_18 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000002054 224.0
PYH2_k127_9234947_19 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000002057 230.0
PYH2_k127_9234947_2 Putative modulator of DNA gyrase K03592 - - 6.042e-202 637.0
PYH2_k127_9234947_21 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000001395 192.0
PYH2_k127_9234947_23 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.000000000000001428 86.0
PYH2_k127_9234947_3 Bacterial regulatory protein, Fis family K07715 - - 2.503e-194 617.0
PYH2_k127_9234947_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 580.0
PYH2_k127_9234947_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 455.0
PYH2_k127_9234947_7 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 414.0
PYH2_k127_9234947_8 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 357.0
PYH2_k127_9234947_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 347.0
PYH2_k127_9298760_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0 999.0
PYH2_k127_9298760_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.133e-242 751.0
PYH2_k127_9298760_2 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 308.0
PYH2_k127_9298760_3 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004702 241.0
PYH2_k127_9298760_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000005306 172.0
PYH2_k127_991387_0 Phosphoglycerate kinase K00927 - 2.7.2.3 3.901e-216 675.0
PYH2_k127_991387_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 608.0
PYH2_k127_991387_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003584 268.0
PYH2_k127_991387_11 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000917 243.0
PYH2_k127_991387_12 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002542 214.0
PYH2_k127_991387_14 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000001413 188.0
PYH2_k127_991387_15 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000001503 188.0
PYH2_k127_991387_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000001612 149.0
PYH2_k127_991387_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000009401 151.0
PYH2_k127_991387_18 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000008365 139.0
PYH2_k127_991387_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000003428 124.0
PYH2_k127_991387_2 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 607.0
PYH2_k127_991387_20 - - - - 0.0000001711 58.0
PYH2_k127_991387_21 PEGA domain - - - 0.0000002322 64.0
PYH2_k127_991387_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 566.0
PYH2_k127_991387_4 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 558.0
PYH2_k127_991387_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 531.0
PYH2_k127_991387_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 519.0
PYH2_k127_991387_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 413.0
PYH2_k127_991387_8 integrase domain protein SAM domain protein K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 298.0
PYH2_k127_991387_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0