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Overview

ID MAG03184
Name PYH2_bin.28
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order UBA4142
Family UBA4142
Genus
Species
Assembly information
Completeness (%) 93.87
Contamination (%) 7.49
GC content (%) 55.0
N50 (bp) 14,551
Genome size (bp) 5,243,222

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4666

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1007324_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000245 241.0
PYH2_k127_1007324_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000001739 233.0
PYH2_k127_1007324_2 Binding-protein-dependent transport system inner membrane component K10119,K10202 - - 0.0000000000000000000000000000000000000000000000000003181 200.0
PYH2_k127_1007324_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000001233 134.0
PYH2_k127_1009964_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 501.0
PYH2_k127_1009964_1 NurA - - - 0.0000000002521 63.0
PYH2_k127_1014458_0 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 417.0
PYH2_k127_1014458_1 Psort location Cytoplasmic, score - - - 0.00000000005176 67.0
PYH2_k127_1020629_0 Cysteine desulfurase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 430.0
PYH2_k127_1020629_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 291.0
PYH2_k127_1020629_2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000005421 210.0
PYH2_k127_1020629_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000009596 166.0
PYH2_k127_1020629_4 Chromate resistance exported protein - - - 0.000000000000000000000000000003241 122.0
PYH2_k127_1021901_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1107.0
PYH2_k127_1021901_1 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 449.0
PYH2_k127_1021901_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 376.0
PYH2_k127_1021901_3 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 293.0
PYH2_k127_1021901_4 Cytochrome c - - - 0.0000000000000000000002849 107.0
PYH2_k127_1021901_5 Secreted repeat of unknown function - - - 0.00000000009285 64.0
PYH2_k127_1021901_6 - - - - 0.0000000008283 70.0
PYH2_k127_1028738_0 PFAM glycosyl transferase group 1 K12993 - - 0.00000000000000000000003351 109.0
PYH2_k127_1028738_1 sterol 24-C-methyltransferase activity K05929 GO:0000003,GO:0000773,GO:0000902,GO:0000904,GO:0001505,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006629,GO:0006644,GO:0006650,GO:0006656,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007275,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008610,GO:0008654,GO:0008757,GO:0009058,GO:0009308,GO:0009309,GO:0009555,GO:0009605,GO:0009653,GO:0009791,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010183,GO:0016043,GO:0016049,GO:0016740,GO:0016741,GO:0019637,GO:0019695,GO:0022414,GO:0022622,GO:0030154,GO:0032259,GO:0032501,GO:0032502,GO:0032989,GO:0034641,GO:0040007,GO:0040011,GO:0042133,GO:0042136,GO:0042221,GO:0042330,GO:0042401,GO:0042425,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0045017,GO:0046470,GO:0046474,GO:0046486,GO:0048229,GO:0048364,GO:0048468,GO:0048528,GO:0048588,GO:0048589,GO:0048731,GO:0048856,GO:0048868,GO:0048869,GO:0050896,GO:0050918,GO:0051704,GO:0052667,GO:0060560,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0080101,GO:0090407,GO:0090696,GO:0097164,GO:0099402,GO:1901564,GO:1901566,GO:1901576 2.1.1.103 0.00000684 57.0
PYH2_k127_1035595_0 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 565.0
PYH2_k127_1035595_1 Binding-protein-dependent transport system inner membrane component K17319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 386.0
PYH2_k127_1035595_10 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000081 123.0
PYH2_k127_1035595_11 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000004107 104.0
PYH2_k127_1035595_12 Transglutaminase-like superfamily - - - 0.00000000000000000003104 95.0
PYH2_k127_1035595_2 Binding-protein-dependent transport system inner membrane component K17320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 303.0
PYH2_k127_1035595_3 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
PYH2_k127_1035595_4 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000001989 259.0
PYH2_k127_1035595_5 inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
PYH2_k127_1035595_6 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001945 235.0
PYH2_k127_1035595_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000002482 196.0
PYH2_k127_1035595_8 Transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000007084 191.0
PYH2_k127_1035595_9 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000001119 140.0
PYH2_k127_1045313_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.977e-262 816.0
PYH2_k127_1045313_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 507.0
PYH2_k127_1045313_10 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0005555 44.0
PYH2_k127_1045313_2 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 384.0
PYH2_k127_1045313_3 Dam-replacing family K01155 - 3.1.21.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 316.0
PYH2_k127_1045313_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
PYH2_k127_1045313_5 Permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 309.0
PYH2_k127_1045313_6 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 307.0
PYH2_k127_1045313_7 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000001444 184.0
PYH2_k127_1045313_8 Purine catabolism regulatory protein-like family K09684 - - 0.00000000000000000000000000000000000001552 162.0
PYH2_k127_1045313_9 Creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000003584 144.0
PYH2_k127_1046904_0 Uncharacterised protein family (UPF0182) K09118 - - 5.442e-241 773.0
PYH2_k127_1048226_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 370.0
PYH2_k127_1048226_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 314.0
PYH2_k127_1048226_2 ABC transporter, permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000276 288.0
PYH2_k127_1048226_3 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000001289 146.0
PYH2_k127_1048226_4 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000001539 123.0
PYH2_k127_1048226_5 - - - - 0.0000000000000002081 85.0
PYH2_k127_1056994_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 478.0
PYH2_k127_1056994_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004243 275.0
PYH2_k127_1056994_2 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000001058 201.0
PYH2_k127_1056994_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000001298 122.0
PYH2_k127_1056994_4 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000005362 110.0
PYH2_k127_1072206_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 541.0
PYH2_k127_1072206_1 KR domain K00038 - 1.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 415.0
PYH2_k127_1072206_2 Protein of unknown function (DUF642) - - - 0.0000000000000000000376 96.0
PYH2_k127_1072206_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000006455 67.0
PYH2_k127_108118_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1149.0
PYH2_k127_108118_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 325.0
PYH2_k127_108118_2 - - - - 0.0000000000000000000000000000000000000009286 162.0
PYH2_k127_108118_3 - - - - 0.000000000000000000000000000005205 123.0
PYH2_k127_108118_4 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000005719 114.0
PYH2_k127_108118_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000006374 108.0
PYH2_k127_108118_6 Sigma-70, region 4 K03088 - - 0.0000000000000000006868 93.0
PYH2_k127_108118_7 Transposase - - - 0.000008926 51.0
PYH2_k127_10881_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 1.062e-204 675.0
PYH2_k127_10881_1 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 437.0
PYH2_k127_10881_10 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000000005153 105.0
PYH2_k127_10881_11 Glycosyl hydrolases family 31 K01811 - 3.2.1.177 0.0000000000000000000009671 111.0
PYH2_k127_10881_12 redox-active disulfide protein 2 - - - 0.0000000000000000000009762 97.0
PYH2_k127_10881_13 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000002242 100.0
PYH2_k127_10881_14 low-complexity proteins - - - 0.0000000000000001856 87.0
PYH2_k127_10881_15 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000001615 72.0
PYH2_k127_10881_16 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000004608 65.0
PYH2_k127_10881_17 Belongs to the glycosyl hydrolase 18 family K01183 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008061,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0030154,GO:0030435,GO:0032502,GO:0042737,GO:0043170,GO:0043934,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046348,GO:0048646,GO:0048856,GO:0048869,GO:0071704,GO:0097367,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.2.1.14 0.00000461 60.0
PYH2_k127_10881_18 - - - - 0.0001872 48.0
PYH2_k127_10881_2 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
PYH2_k127_10881_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 414.0
PYH2_k127_10881_4 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000006778 272.0
PYH2_k127_10881_6 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000003279 168.0
PYH2_k127_10881_7 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000000000000000006697 148.0
PYH2_k127_10881_8 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000002766 145.0
PYH2_k127_10881_9 - - - - 0.000000000000000000000000001961 116.0
PYH2_k127_1100221_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 504.0
PYH2_k127_1100221_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002065 256.0
PYH2_k127_1105070_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 508.0
PYH2_k127_1105070_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 533.0
PYH2_k127_1105070_10 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000196 247.0
PYH2_k127_1105070_11 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000002472 205.0
PYH2_k127_1105070_12 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000005376 202.0
PYH2_k127_1105070_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000003532 175.0
PYH2_k127_1105070_14 Glycosyltransferase family 87 - - - 0.0000000000000000000000000003716 130.0
PYH2_k127_1105070_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000005119 119.0
PYH2_k127_1105070_16 Pfam:DUF385 - - - 0.00000000000000002793 85.0
PYH2_k127_1105070_17 Membrane - - - 0.00000000000000008803 96.0
PYH2_k127_1105070_18 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001751 54.0
PYH2_k127_1105070_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 498.0
PYH2_k127_1105070_3 PUA-like domain K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 490.0
PYH2_k127_1105070_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
PYH2_k127_1105070_5 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 437.0
PYH2_k127_1105070_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 337.0
PYH2_k127_1105070_7 transferase activity, transferring glycosyl groups K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 295.0
PYH2_k127_1105070_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001079 295.0
PYH2_k127_1105070_9 Predicted membrane protein (DUF2079) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001653 280.0
PYH2_k127_1117537_0 PFAM Cytochrome C assembly protein K02198 - - 2.976e-198 638.0
PYH2_k127_1117537_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 578.0
PYH2_k127_1117537_10 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 377.0
PYH2_k127_1117537_11 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 353.0
PYH2_k127_1117537_12 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 334.0
PYH2_k127_1117537_13 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 306.0
PYH2_k127_1117537_14 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 313.0
PYH2_k127_1117537_15 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 305.0
PYH2_k127_1117537_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006401 246.0
PYH2_k127_1117537_17 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006021 244.0
PYH2_k127_1117537_18 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003188 239.0
PYH2_k127_1117537_19 cellular response to dsDNA K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003195 230.0
PYH2_k127_1117537_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 550.0
PYH2_k127_1117537_20 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000456 226.0
PYH2_k127_1117537_21 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000004761 210.0
PYH2_k127_1117537_22 TIGRFAM TIGR02453 family protein - - - 0.000000000000000000000000000000000000000000000000000001415 199.0
PYH2_k127_1117537_23 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000002147 196.0
PYH2_k127_1117537_24 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000004964 176.0
PYH2_k127_1117537_25 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000005003 182.0
PYH2_k127_1117537_26 PAS domain - - - 0.000000000000000000000000000000000000000009122 158.0
PYH2_k127_1117537_27 - - - - 0.00000000000000000000000000000000000000003801 166.0
PYH2_k127_1117537_29 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000006682 142.0
PYH2_k127_1117537_3 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 537.0
PYH2_k127_1117537_30 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000006125 146.0
PYH2_k127_1117537_31 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000004833 137.0
PYH2_k127_1117537_32 Two component regulator propeller - - - 0.00000000000000000000000000001482 138.0
PYH2_k127_1117537_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000001804 132.0
PYH2_k127_1117537_34 subunit of a heme lyase K02200 - - 0.0000000000000000000000000003132 121.0
PYH2_k127_1117537_35 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000005248 113.0
PYH2_k127_1117537_36 Glycosyl hydrolase catalytic core - - - 0.00000000000000000000000007809 119.0
PYH2_k127_1117537_37 Glyoxalase-like domain - - - 0.0000000000000000000001134 106.0
PYH2_k127_1117537_38 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000006787 98.0
PYH2_k127_1117537_39 heat shock protein binding - - - 0.00000000000000000003618 100.0
PYH2_k127_1117537_4 peptidase K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 544.0
PYH2_k127_1117537_40 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000002902 95.0
PYH2_k127_1117537_41 PFAM regulatory protein, ArsR K03892 - - 0.00000000000000002928 86.0
PYH2_k127_1117537_42 4Fe-4S dicluster domain K00196 - - 0.000000006051 59.0
PYH2_k127_1117537_44 - - - - 0.000001607 55.0
PYH2_k127_1117537_45 PFAM Lecithin cholesterol acyltransferase - - - 0.00001159 59.0
PYH2_k127_1117537_46 Cupin 2, conserved barrel domain protein - - - 0.00009637 49.0
PYH2_k127_1117537_47 PilZ domain - - - 0.0001357 50.0
PYH2_k127_1117537_5 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 464.0
PYH2_k127_1117537_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 450.0
PYH2_k127_1117537_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 423.0
PYH2_k127_1117537_8 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 407.0
PYH2_k127_1117537_9 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 379.0
PYH2_k127_1118126_0 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 529.0
PYH2_k127_1118126_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
PYH2_k127_1118126_2 Transcriptional regulator - - - 0.00000000000000000000005023 111.0
PYH2_k127_1124073_0 PFAM glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000008496 218.0
PYH2_k127_1125534_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.443e-293 919.0
PYH2_k127_1125534_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.876e-223 704.0
PYH2_k127_1125534_10 Cupin 2, conserved barrel domain protein - - - 0.00000000003363 68.0
PYH2_k127_1125534_12 PFAM FHA domain - - - 0.00006187 52.0
PYH2_k127_1125534_2 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 540.0
PYH2_k127_1125534_3 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 437.0
PYH2_k127_1125534_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 382.0
PYH2_k127_1125534_5 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 357.0
PYH2_k127_1125534_6 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007023 257.0
PYH2_k127_1125534_7 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000000002688 182.0
PYH2_k127_1125534_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000007295 124.0
PYH2_k127_1132939_0 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 312.0
PYH2_k127_1132939_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 284.0
PYH2_k127_1132939_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000002775 165.0
PYH2_k127_1132939_3 FCD domain protein - - - 0.00000000000000000000000000004547 125.0
PYH2_k127_1135322_0 SMART Elongator protein 3 MiaB NifB - - - 1.73e-236 742.0
PYH2_k127_1135322_1 NAD(P)H-binding K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 401.0
PYH2_k127_1135322_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 404.0
PYH2_k127_1135322_3 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 323.0
PYH2_k127_1135322_4 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000001299 218.0
PYH2_k127_1135322_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000001462 192.0
PYH2_k127_1135322_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000007054 151.0
PYH2_k127_1135322_7 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000001275 143.0
PYH2_k127_1135322_8 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000002849 97.0
PYH2_k127_1135322_9 Glucose / Sorbosone dehydrogenase - - - 0.0000003478 55.0
PYH2_k127_1135915_0 epimerase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 541.0
PYH2_k127_1135915_1 - - - - 0.0000000000000000000000000000000000000000000000007796 182.0
PYH2_k127_1135915_2 acetyltransferase K00621 - 2.3.1.4 0.0000000000000000000000000000000002925 143.0
PYH2_k127_1135915_3 - - - - 0.000000000000001269 79.0
PYH2_k127_1135915_4 Carboxymuconolactone decarboxylase family - - - 0.00001661 47.0
PYH2_k127_1139271_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 512.0
PYH2_k127_1139271_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 460.0
PYH2_k127_1139271_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
PYH2_k127_1139271_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000008609 228.0
PYH2_k127_1139271_4 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000008054 177.0
PYH2_k127_1139271_5 Protein of unknown function (DUF2281) - - - 0.0000000000001021 75.0
PYH2_k127_1139271_6 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000003735 64.0
PYH2_k127_1139271_7 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000001081 57.0
PYH2_k127_1139271_8 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000002274 59.0
PYH2_k127_1139271_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0002773 49.0
PYH2_k127_1151236_0 PFAM Transposase IS3 IS911 K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 400.0
PYH2_k127_1151236_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000002908 179.0
PYH2_k127_1151236_2 Transposase and inactivated derivatives - - - 0.00000000000000000000000000001801 120.0
PYH2_k127_1151236_3 SnoaL-like polyketide cyclase - - - 0.000000000000000000001028 98.0
PYH2_k127_1162132_0 - - - - 0.00000000000000000000000000000000000000000000000000000000009956 212.0
PYH2_k127_1162132_2 - - - - 0.0000000000000000000005461 102.0
PYH2_k127_1162132_3 - - - - 0.00000000000000112 78.0
PYH2_k127_1162132_4 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0001412 49.0
PYH2_k127_1162499_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 488.0
PYH2_k127_1162499_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000005666 238.0
PYH2_k127_1162499_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000006951 124.0
PYH2_k127_1162499_3 HAD-hyrolase-like K07025 - - 0.00000000000000005624 90.0
PYH2_k127_1162499_4 Regulatory protein RecX K03565 - - 0.000001522 51.0
PYH2_k127_1178522_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001499 294.0
PYH2_k127_1178522_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000005992 235.0
PYH2_k127_1178522_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000102 225.0
PYH2_k127_1178522_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000001183 218.0
PYH2_k127_1178522_4 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000001091 215.0
PYH2_k127_1178522_5 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000001868 183.0
PYH2_k127_1208682_0 Endoribonuclease L-PSP K04782 - 4.2.99.21 0.000000000000000000000000000000000000000000000000000005251 192.0
PYH2_k127_1208682_1 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000002909 156.0
PYH2_k127_1226188_0 Creatinase/Prolidase N-terminal domain K18829 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 396.0
PYH2_k127_1226188_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 317.0
PYH2_k127_1226188_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001436 278.0
PYH2_k127_1226188_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000006971 261.0
PYH2_k127_1226188_4 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006831 259.0
PYH2_k127_1226188_5 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003435 256.0
PYH2_k127_1226188_6 UTRA K03710 - - 0.0000000000000000000000000000000000000000000734 169.0
PYH2_k127_1226188_7 ABC-type sugar transport system periplasmic component - - - 0.000000000000000000000000000000001672 146.0
PYH2_k127_1226188_8 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000004239 132.0
PYH2_k127_1258484_0 PFAM 5'-nucleotidase, C-terminal domain K07004 - - 1.801e-203 676.0
PYH2_k127_1258484_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 443.0
PYH2_k127_1258484_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000007174 202.0
PYH2_k127_1258484_11 - - - - 0.000000000000000000000000000000000000000000000000000003502 199.0
PYH2_k127_1258484_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000006233 198.0
PYH2_k127_1258484_13 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000003293 193.0
PYH2_k127_1258484_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000000000000000001538 187.0
PYH2_k127_1258484_15 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000004345 183.0
PYH2_k127_1258484_16 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000001272 169.0
PYH2_k127_1258484_17 Thioredoxin domain - - - 0.000000000000000000000000000000000000001917 151.0
PYH2_k127_1258484_18 Thioredoxin K03671 - - 0.00000000000000000000000000000000000003892 146.0
PYH2_k127_1258484_19 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000004757 141.0
PYH2_k127_1258484_2 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 435.0
PYH2_k127_1258484_20 Major Facilitator Superfamily - - - 0.000000000000000000000000000000001426 138.0
PYH2_k127_1258484_21 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000005648 136.0
PYH2_k127_1258484_22 thiolester hydrolase activity K03186 - 2.5.1.129 0.00000000000000000000000000000001118 133.0
PYH2_k127_1258484_23 CoA-binding protein K06929 - - 0.00000000000000000000000000000001558 130.0
PYH2_k127_1258484_24 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000000002172 132.0
PYH2_k127_1258484_25 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000001841 130.0
PYH2_k127_1258484_26 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000001078 115.0
PYH2_k127_1258484_27 - - - - 0.0000000000000000000009178 104.0
PYH2_k127_1258484_28 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.000000000000000006451 85.0
PYH2_k127_1258484_29 Thioredoxin domain - - - 0.00000000000000001931 83.0
PYH2_k127_1258484_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 419.0
PYH2_k127_1258484_30 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K18030 - 1.17.2.1 0.0000000000000001367 80.0
PYH2_k127_1258484_31 branched-chain amino acid - - - 0.000000000000001474 80.0
PYH2_k127_1258484_32 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000001986 78.0
PYH2_k127_1258484_33 COG0477 Permeases of the major facilitator superfamily K08153,K19578 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000007895 84.0
PYH2_k127_1258484_34 transcriptional K21600 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000004079 67.0
PYH2_k127_1258484_35 - - - - 0.000000001467 65.0
PYH2_k127_1258484_36 family 25 K01185,K07273 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.17 0.000000218 64.0
PYH2_k127_1258484_38 Bacterial membrane protein, YfhO - - - 0.00004962 53.0
PYH2_k127_1258484_4 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 334.0
PYH2_k127_1258484_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 312.0
PYH2_k127_1258484_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001007 246.0
PYH2_k127_1258484_8 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001401 224.0
PYH2_k127_1258484_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000004729 214.0
PYH2_k127_128051_0 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 405.0
PYH2_k127_128051_1 PFAM inner-membrane translocator K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 383.0
PYH2_k127_128051_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 324.0
PYH2_k127_128051_3 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000005242 120.0
PYH2_k127_128051_4 - - - - 0.000000000001197 74.0
PYH2_k127_128051_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000003488 55.0
PYH2_k127_1287790_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 5.447e-202 638.0
PYH2_k127_1287790_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 509.0
PYH2_k127_1287790_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000005548 113.0
PYH2_k127_1287790_11 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000007086 98.0
PYH2_k127_1287790_12 - K05826 - - 0.00000000000001733 76.0
PYH2_k127_1287790_2 Belongs to the RimK family K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 411.0
PYH2_k127_1287790_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 355.0
PYH2_k127_1287790_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 306.0
PYH2_k127_1287790_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005715 244.0
PYH2_k127_1287790_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000004022 225.0
PYH2_k127_1287790_7 PFAM imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
PYH2_k127_1287790_8 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000003496 148.0
PYH2_k127_1287790_9 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000127 150.0
PYH2_k127_1293747_0 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.0000000000000000000000000000000000000004763 154.0
PYH2_k127_1293747_1 Transposase - - - 0.000000000000000000000000002853 124.0
PYH2_k127_1330866_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 6.026e-229 730.0
PYH2_k127_1330866_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 507.0
PYH2_k127_1330866_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000003285 78.0
PYH2_k127_1330866_11 Protein of unknown function (DUF2628) - - - 0.000000002064 69.0
PYH2_k127_1330866_12 domain protein K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000008316 59.0
PYH2_k127_1330866_13 Psort location Cytoplasmic, score 8.87 - - - 0.00000006283 61.0
PYH2_k127_1330866_14 Peptidoglycan-binding lysin domain - - - 0.000007692 57.0
PYH2_k127_1330866_15 protein secretion K08651 - 3.4.21.66 0.00001411 55.0
PYH2_k127_1330866_16 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00005869 48.0
PYH2_k127_1330866_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 407.0
PYH2_k127_1330866_3 Protein of unknown function (DUF2723) K14340 - - 0.0000000000000000000000000000000000000000000000000000000000000000001466 261.0
PYH2_k127_1330866_4 manganese ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000009705 241.0
PYH2_k127_1330866_5 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000008533 217.0
PYH2_k127_1330866_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000002786 160.0
PYH2_k127_1330866_7 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000000000000000000000000269 141.0
PYH2_k127_1330866_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000001316 129.0
PYH2_k127_1330866_9 - - - - 0.000000000000000000000000000002638 128.0
PYH2_k127_1339345_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000001086 50.0
PYH2_k127_1339345_1 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.00008441 56.0
PYH2_k127_1359316_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 345.0
PYH2_k127_1359316_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000001814 168.0
PYH2_k127_1376585_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 539.0
PYH2_k127_1376585_1 radical SAM protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 511.0
PYH2_k127_1376585_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 330.0
PYH2_k127_1376585_11 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 320.0
PYH2_k127_1376585_12 Two component transcriptional regulator, winged helix family K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 305.0
PYH2_k127_1376585_13 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 298.0
PYH2_k127_1376585_14 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006824 257.0
PYH2_k127_1376585_15 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 235.0
PYH2_k127_1376585_16 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000009896 238.0
PYH2_k127_1376585_17 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001586 237.0
PYH2_k127_1376585_18 [2Fe-2S] binding domain K07302,K18029 - 1.17.2.1,1.3.99.16 0.00000000000000000000000000000000000000000000000000000002602 200.0
PYH2_k127_1376585_19 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000005397 170.0
PYH2_k127_1376585_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 484.0
PYH2_k127_1376585_20 PFAM membrane-flanked domain - - - 0.0000000000000000000000000000000001424 140.0
PYH2_k127_1376585_21 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000004346 132.0
PYH2_k127_1376585_22 Amino acid permease - - - 0.000000001107 65.0
PYH2_k127_1376585_23 Amidohydrolase family - - - 0.00002741 48.0
PYH2_k127_1376585_3 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 413.0
PYH2_k127_1376585_4 PFAM ABC transporter related K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 398.0
PYH2_k127_1376585_5 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 382.0
PYH2_k127_1376585_6 Belongs to the bacterial solute-binding protein 3 family K02030,K09969,K10039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 361.0
PYH2_k127_1376585_7 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 346.0
PYH2_k127_1376585_8 Zn-dependent dipeptidase, microsomal dipeptidase K01273,K01274 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 342.0
PYH2_k127_1376585_9 Binding-protein-dependent transport system inner membrane component K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 342.0
PYH2_k127_1381598_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 429.0
PYH2_k127_1381598_1 ABC-type multidrug transport system ATPase and permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 359.0
PYH2_k127_1381598_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 366.0
PYH2_k127_1396575_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 349.0
PYH2_k127_1396575_1 PFAM type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000001596 229.0
PYH2_k127_1396575_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
PYH2_k127_1396575_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000004418 193.0
PYH2_k127_1396575_4 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000001732 174.0
PYH2_k127_1396575_5 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000001002 168.0
PYH2_k127_1396575_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000004654 158.0
PYH2_k127_1396575_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000005275 123.0
PYH2_k127_1396575_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000003471 67.0
PYH2_k127_1420692_0 belongs to the sigma-70 factor family, ECF subfamily - - - 0.0000000000000000000000000000003285 130.0
PYH2_k127_1420692_1 - K08982 - - 0.0000000001795 66.0
PYH2_k127_1420692_2 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000265 61.0
PYH2_k127_1420692_3 Short C-terminal domain K08982 - - 0.00000004076 57.0
PYH2_k127_1420692_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.000001824 53.0
PYH2_k127_143641_0 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 302.0
PYH2_k127_143641_1 COG3209 Rhs family protein K01387 - 3.4.24.3 0.0000000000000000000000000001389 134.0
PYH2_k127_143641_2 Membrane - - - 0.0000000000000000000002922 113.0
PYH2_k127_143641_3 sugar transferase - - - 0.0000000000000004412 79.0
PYH2_k127_1461987_0 Belongs to the thiolase family K00626 - 2.3.1.9 1.485e-218 685.0
PYH2_k127_1461987_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000001774 191.0
PYH2_k127_1461987_2 Acetyltransferase (GNAT) domain K03828 - - 0.000000000000000000000008016 106.0
PYH2_k127_1477008_0 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 372.0
PYH2_k127_1477008_1 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 392.0
PYH2_k127_1477008_2 amidohydrolase K21613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 337.0
PYH2_k127_1477008_3 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000172 289.0
PYH2_k127_1477008_4 PFAM N-acylglucosamine 2-epimerase K01787 - 5.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002083 282.0
PYH2_k127_1477008_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001087 276.0
PYH2_k127_1477008_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000007443 269.0
PYH2_k127_1477008_7 purine nucleotide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002285 268.0
PYH2_k127_1477008_8 Mannose-6-phosphate isomerase K01485 - 3.5.4.1 0.000006934 53.0
PYH2_k127_1493052_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 490.0
PYH2_k127_1493052_1 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000001796 216.0
PYH2_k127_1493052_2 PFAM membrane protein of K08972 - - 0.00000000000000000000001502 106.0
PYH2_k127_1493052_3 PFAM Transglycosylase-associated protein - - - 0.00000000000000000001406 93.0
PYH2_k127_1493052_4 Cation transport regulator K06197 - - 0.000000000000001015 81.0
PYH2_k127_1541569_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 497.0
PYH2_k127_1541569_1 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 479.0
PYH2_k127_1541569_2 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 436.0
PYH2_k127_1541569_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005643 270.0
PYH2_k127_1541569_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005103 249.0
PYH2_k127_1541569_5 Patatin-like phospholipase K01999,K07001 - - 0.0000000000000000000000000000000000000000000000000000000000002334 233.0
PYH2_k127_1541569_6 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000004817 168.0
PYH2_k127_1541569_7 response to abiotic stimulus - - - 0.0000000000000000000000000000000000000009978 157.0
PYH2_k127_1551587_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 294.0
PYH2_k127_1551587_1 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002683 244.0
PYH2_k127_1551587_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000003347 188.0
PYH2_k127_1551587_3 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000000003021 130.0
PYH2_k127_158951_0 Amidohydrolase family K06015 - 3.5.1.81 5.996e-202 642.0
PYH2_k127_158951_1 catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 536.0
PYH2_k127_158951_10 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000000000000000000000000889 180.0
PYH2_k127_158951_11 - - - - 0.00000000000000000000000000000000004645 148.0
PYH2_k127_158951_12 - - - - 0.0000000000000000000000000000003627 135.0
PYH2_k127_158951_13 - - - - 0.000000000000000000000000000109 126.0
PYH2_k127_158951_14 - - - - 0.000000000000000000000000002146 123.0
PYH2_k127_158951_15 methyltransferase activity - - - 0.000000000000000000000002584 112.0
PYH2_k127_158951_16 Histidine kinase - - - 0.0000007887 56.0
PYH2_k127_158951_18 Double zinc ribbon - - - 0.0002278 54.0
PYH2_k127_158951_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 519.0
PYH2_k127_158951_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 422.0
PYH2_k127_158951_4 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 376.0
PYH2_k127_158951_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 375.0
PYH2_k127_158951_6 Flavin-binding monooxygenase-like K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 375.0
PYH2_k127_158951_7 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 337.0
PYH2_k127_158951_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
PYH2_k127_158951_9 MutL protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002423 252.0
PYH2_k127_1628843_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 413.0
PYH2_k127_1628843_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000006501 196.0
PYH2_k127_1628843_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000000000000000000000000002999 177.0
PYH2_k127_1647903_0 PFAM glycosyl transferase, family 51 - - - 4.089e-281 897.0
PYH2_k127_1647903_1 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 503.0
PYH2_k127_1647903_10 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000001534 241.0
PYH2_k127_1647903_11 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
PYH2_k127_1647903_12 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000002642 231.0
PYH2_k127_1647903_13 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000002701 218.0
PYH2_k127_1647903_14 rRNA processing K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000719 205.0
PYH2_k127_1647903_15 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000001294 204.0
PYH2_k127_1647903_16 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000003527 179.0
PYH2_k127_1647903_17 Thiol-disulfide oxidoreductase DCC - - - 0.0000000000000000000000000000000000002364 144.0
PYH2_k127_1647903_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000002125 145.0
PYH2_k127_1647903_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000001081 124.0
PYH2_k127_1647903_2 Aminotransferase K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 473.0
PYH2_k127_1647903_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000023 106.0
PYH2_k127_1647903_21 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000001029 102.0
PYH2_k127_1647903_22 aminotransferase class I and II K10907 - - 0.00000000000319 66.0
PYH2_k127_1647903_23 Protein of unknown function (DUF1648) - - - 0.00000000001753 70.0
PYH2_k127_1647903_25 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000008938 64.0
PYH2_k127_1647903_29 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0002185 50.0
PYH2_k127_1647903_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 428.0
PYH2_k127_1647903_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
PYH2_k127_1647903_5 Nucleotidyl transferase K00973,K04042 - 2.3.1.157,2.7.7.23,2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 360.0
PYH2_k127_1647903_6 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 314.0
PYH2_k127_1647903_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 297.0
PYH2_k127_1647903_8 Protein of unknown function DUF89 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 299.0
PYH2_k127_1647903_9 formate dehydrogenase (NAD+) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005863 276.0
PYH2_k127_1678229_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 372.0
PYH2_k127_1678229_1 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
PYH2_k127_1678229_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
PYH2_k127_1678229_3 PFAM secretion protein HlyD family protein K02005 - - 0.00000000000000000000000000000000000000001212 169.0
PYH2_k127_1678229_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000001679 124.0
PYH2_k127_1678229_5 - - - - 0.0001398 49.0
PYH2_k127_1678229_6 Domain of unknown function (DUF4349) - - - 0.0003293 49.0
PYH2_k127_1685941_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 335.0
PYH2_k127_1685941_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000001433 102.0
PYH2_k127_1685941_2 AAA ATPase domain - - - 0.000000000000000004166 99.0
PYH2_k127_1685941_3 AAA ATPase domain - - - 0.00000001583 59.0
PYH2_k127_1705534_0 Phage portal protein, lambda family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 401.0
PYH2_k127_1705534_1 Mu-like prophage major head subunit gpT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001143 267.0
PYH2_k127_1714849_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000001357 160.0
PYH2_k127_1714849_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000001488 145.0
PYH2_k127_1720536_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 346.0
PYH2_k127_1720536_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001954 272.0
PYH2_k127_1720536_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002463 256.0
PYH2_k127_1720536_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000003776 158.0
PYH2_k127_1738866_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.792e-208 667.0
PYH2_k127_1738866_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 597.0
PYH2_k127_1738866_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000004445 83.0
PYH2_k127_1738866_2 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000011 287.0
PYH2_k127_1738866_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000001768 266.0
PYH2_k127_1738866_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000001277 176.0
PYH2_k127_1738866_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000578 145.0
PYH2_k127_1738866_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000002427 139.0
PYH2_k127_1738866_7 Major Facilitator Superfamily - - - 0.00000000000000000000000001062 116.0
PYH2_k127_1738866_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000301 96.0
PYH2_k127_1738866_9 Asp23 family, cell envelope-related function - - - 0.000000000000000009738 87.0
PYH2_k127_1761186_0 Heat shock 70 kDa protein K04043 - - 1.894e-287 895.0
PYH2_k127_1761186_1 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 432.0
PYH2_k127_1761186_10 - - - - 0.000000000000005827 83.0
PYH2_k127_1761186_11 PFAM Lysine exporter protein (LYSE YGGA) K06895 - - 0.000000000000007081 75.0
PYH2_k127_1761186_2 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
PYH2_k127_1761186_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 303.0
PYH2_k127_1761186_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007506 269.0
PYH2_k127_1761186_5 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000002453 250.0
PYH2_k127_1761186_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000001177 193.0
PYH2_k127_1761186_7 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000116 170.0
PYH2_k127_1761186_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000003176 149.0
PYH2_k127_1761186_9 - - - - 0.000000000000000000000000000000001739 134.0
PYH2_k127_1809433_0 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 400.0
PYH2_k127_1809433_1 PFAM binding-protein-dependent transport systems inner membrane component K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000431 273.0
PYH2_k127_1809433_2 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001537 248.0
PYH2_k127_1809433_3 ABC transporter substrate-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 250.0
PYH2_k127_1829142_0 Histidine kinase-like ATPases - - - 3.837e-219 739.0
PYH2_k127_1829142_1 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 376.0
PYH2_k127_1829142_2 SMART HNH nuclease - - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
PYH2_k127_1829142_3 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000003899 164.0
PYH2_k127_1829142_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000006648 85.0
PYH2_k127_1844182_0 intracellular signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 559.0
PYH2_k127_1851799_0 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 313.0
PYH2_k127_1851799_1 PFAM dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 305.0
PYH2_k127_1851799_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001038 270.0
PYH2_k127_1851799_3 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 254.0
PYH2_k127_1851799_4 PFAM glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000008302 204.0
PYH2_k127_1851799_6 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000004619 100.0
PYH2_k127_1851799_7 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.000000000000000009208 97.0
PYH2_k127_1862441_0 CoA-ligase K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
PYH2_k127_1862441_1 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 558.0
PYH2_k127_1862441_2 xanthine dehydrogenase activity K03519,K19818 - 1.2.5.3,1.5.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 302.0
PYH2_k127_1862441_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000008293 240.0
PYH2_k127_1862441_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000007574 243.0
PYH2_k127_1862441_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000004944 213.0
PYH2_k127_1862441_6 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000001147 125.0
PYH2_k127_1868263_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1669.0
PYH2_k127_1868263_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1173.0
PYH2_k127_1868263_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.343e-281 880.0
PYH2_k127_1868263_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
PYH2_k127_1868263_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001684 220.0
PYH2_k127_1868263_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000001987 200.0
PYH2_k127_1868263_6 - - - - 0.0009906 45.0
PYH2_k127_1955963_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009185 280.0
PYH2_k127_1955963_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000008679 153.0
PYH2_k127_1955963_2 DNA-binding transcription factor activity - - - 0.000000000262 65.0
PYH2_k127_1955963_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0009201 45.0
PYH2_k127_1974130_0 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 579.0
PYH2_k127_1974130_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 483.0
PYH2_k127_1974130_2 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003102 260.0
PYH2_k127_1974130_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001139 220.0
PYH2_k127_1974130_4 Serine aminopeptidase, S33 - - - 0.00000001201 57.0
PYH2_k127_1981953_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 540.0
PYH2_k127_1981953_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000245 221.0
PYH2_k127_1981953_2 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000004967 145.0
PYH2_k127_1998373_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 449.0
PYH2_k127_1998373_1 A-macroglobulin receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 324.0
PYH2_k127_1998373_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 292.0
PYH2_k127_1998373_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000003875 148.0
PYH2_k127_2002498_0 ATPase domain predominantly from Archaea K06921 - - 0.000000000000000000000000000000000000000000000000000001258 203.0
PYH2_k127_2002498_1 TIGRFAM transposase, IS605 OrfB K07496 - - 0.000000000000000000000000000000000000000000000001838 189.0
PYH2_k127_200419_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 8.962e-270 855.0
PYH2_k127_200419_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 537.0
PYH2_k127_200419_10 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 382.0
PYH2_k127_200419_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 348.0
PYH2_k127_200419_12 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 331.0
PYH2_k127_200419_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 334.0
PYH2_k127_200419_14 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 314.0
PYH2_k127_200419_15 ABC transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 289.0
PYH2_k127_200419_16 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 289.0
PYH2_k127_200419_17 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001126 290.0
PYH2_k127_200419_18 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009289 294.0
PYH2_k127_200419_19 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001093 278.0
PYH2_k127_200419_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 511.0
PYH2_k127_200419_20 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000006053 258.0
PYH2_k127_200419_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001474 248.0
PYH2_k127_200419_22 PFAM glutamine amidotransferase class-I K07010 - - 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
PYH2_k127_200419_23 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000003628 213.0
PYH2_k127_200419_24 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000006235 175.0
PYH2_k127_200419_25 protein secretion K15125,K20276 - - 0.00000000000000000000000000000000000000001377 170.0
PYH2_k127_200419_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000002411 156.0
PYH2_k127_200419_27 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05889,K12678 - 1.1.2.6 0.000000000000000000000000000000003966 144.0
PYH2_k127_200419_28 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000146 128.0
PYH2_k127_200419_29 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000004269 117.0
PYH2_k127_200419_3 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 487.0
PYH2_k127_200419_30 Mechanosensitive ion channel K03442 - - 0.00000000000000000000006801 105.0
PYH2_k127_200419_31 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000003307 111.0
PYH2_k127_200419_32 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.000000000000000000008079 107.0
PYH2_k127_200419_33 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000002448 89.0
PYH2_k127_200419_34 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000002953 96.0
PYH2_k127_200419_35 DNA photolyase domain protein K01669 - 4.1.99.3 0.00000000000001905 74.0
PYH2_k127_200419_36 Ig-like domain from next to BRCA1 gene - - - 0.0000000000005533 82.0
PYH2_k127_200419_37 Domain of unknown function (DUF4129) - - - 0.00000000003831 76.0
PYH2_k127_200419_38 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000005561 75.0
PYH2_k127_200419_39 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000001439 61.0
PYH2_k127_200419_4 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 440.0
PYH2_k127_200419_40 transposase activity - - - 0.000009836 55.0
PYH2_k127_200419_41 cellulase activity - - - 0.0000164 55.0
PYH2_k127_200419_42 His Kinase A (phosphoacceptor) domain - - - 0.0000884 52.0
PYH2_k127_200419_43 - - - - 0.0002158 54.0
PYH2_k127_200419_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 434.0
PYH2_k127_200419_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 420.0
PYH2_k127_200419_7 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 420.0
PYH2_k127_200419_8 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 402.0
PYH2_k127_200419_9 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
PYH2_k127_2013903_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 7.638e-248 786.0
PYH2_k127_2013903_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 512.0
PYH2_k127_2013903_10 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000002808 205.0
PYH2_k127_2013903_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000001298 120.0
PYH2_k127_2013903_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.0000000000000000000000001195 108.0
PYH2_k127_2013903_13 - - - - 0.0000000000000007958 86.0
PYH2_k127_2013903_14 DJ-1/PfpI family K03152 - 3.5.1.124 0.00003692 49.0
PYH2_k127_2013903_15 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001891 53.0
PYH2_k127_2013903_2 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 411.0
PYH2_k127_2013903_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 414.0
PYH2_k127_2013903_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 365.0
PYH2_k127_2013903_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 374.0
PYH2_k127_2013903_6 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001322 298.0
PYH2_k127_2013903_7 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000004029 234.0
PYH2_k127_2013903_8 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000001049 224.0
PYH2_k127_2013903_9 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000002147 215.0
PYH2_k127_2020392_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 341.0
PYH2_k127_2020392_1 PFAM Cyclic nucleotide-binding K10914,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001004 262.0
PYH2_k127_2022017_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 4.56e-250 782.0
PYH2_k127_2022017_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 8.749e-242 762.0
PYH2_k127_2022017_10 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 382.0
PYH2_k127_2022017_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 374.0
PYH2_k127_2022017_12 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 360.0
PYH2_k127_2022017_13 mevalonate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 350.0
PYH2_k127_2022017_14 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 323.0
PYH2_k127_2022017_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 331.0
PYH2_k127_2022017_16 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 305.0
PYH2_k127_2022017_17 COG1404 Subtilisin-like serine proteases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 334.0
PYH2_k127_2022017_18 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 322.0
PYH2_k127_2022017_19 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003942 272.0
PYH2_k127_2022017_2 ABC transporter K06147 - - 3.333e-232 735.0
PYH2_k127_2022017_20 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
PYH2_k127_2022017_21 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006577 257.0
PYH2_k127_2022017_22 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002444 246.0
PYH2_k127_2022017_23 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004474 252.0
PYH2_k127_2022017_24 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
PYH2_k127_2022017_25 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000001235 239.0
PYH2_k127_2022017_26 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000002208 226.0
PYH2_k127_2022017_27 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000007338 222.0
PYH2_k127_2022017_28 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000002201 228.0
PYH2_k127_2022017_29 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001244 205.0
PYH2_k127_2022017_3 Glucuronate isomerase K01812 - 5.3.1.12 2.84e-208 656.0
PYH2_k127_2022017_30 PFAM cyclic nucleotide-binding K16922 - - 0.00000000000000000000000000000000000000000000000000000005501 214.0
PYH2_k127_2022017_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000001526 186.0
PYH2_k127_2022017_32 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000003766 205.0
PYH2_k127_2022017_33 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000002674 177.0
PYH2_k127_2022017_34 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000004783 162.0
PYH2_k127_2022017_35 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000003415 160.0
PYH2_k127_2022017_36 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000003237 152.0
PYH2_k127_2022017_37 Glutamate synthase - - - 0.0000000000000000000000000000000004682 139.0
PYH2_k127_2022017_38 NUDIX domain - - - 0.00000000000000000000000000000005607 134.0
PYH2_k127_2022017_39 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000001083 124.0
PYH2_k127_2022017_4 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 4.166e-206 650.0
PYH2_k127_2022017_40 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000001822 121.0
PYH2_k127_2022017_41 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000004602 102.0
PYH2_k127_2022017_42 TIGRFAM hydrogenase maturation protease - - - 0.00000000000000001485 89.0
PYH2_k127_2022017_43 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000008479 76.0
PYH2_k127_2022017_45 interspecies interaction between organisms - - - 0.0000002326 55.0
PYH2_k127_2022017_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 589.0
PYH2_k127_2022017_6 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 490.0
PYH2_k127_2022017_7 Associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 459.0
PYH2_k127_2022017_8 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 442.0
PYH2_k127_2022017_9 PFAM VWA containing CoxE family protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
PYH2_k127_2024890_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 385.0
PYH2_k127_2024890_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 383.0
PYH2_k127_2024890_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000006757 163.0
PYH2_k127_2048353_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 3.826e-296 919.0
PYH2_k127_2048353_1 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 582.0
PYH2_k127_2048353_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 417.0
PYH2_k127_2048353_4 TIGRFAM MoaD family protein K03636 - - 0.000000000000000004032 87.0
PYH2_k127_2048353_5 COG1977 Molybdopterin converting factor, small subunit - - - 0.00000008713 57.0
PYH2_k127_2048353_6 TIGRFAM MoaD family protein K03636 - - 0.0001373 48.0
PYH2_k127_2049886_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 402.0
PYH2_k127_2049886_1 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 355.0
PYH2_k127_2049886_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000004683 204.0
PYH2_k127_2049886_3 Methyltransferase domain K06987 - - 0.000000000000000000000000000000000000000000006935 173.0
PYH2_k127_2049886_4 metal-dependent membrane protease K07052 - - 0.000000000000000000000000000000006163 141.0
PYH2_k127_2049886_5 CAAX protease self-immunity - - - 0.000000000000000002226 95.0
PYH2_k127_2049886_7 - - - - 0.0000000001836 68.0
PYH2_k127_2049886_8 - - - - 0.00000001108 62.0
PYH2_k127_2051164_0 Alpha amylase, catalytic domain - - - 0.0 1284.0
PYH2_k127_2051164_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 419.0
PYH2_k127_2051164_10 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000001122 126.0
PYH2_k127_2051164_11 Nitroreductase family - - - 0.000000000000000000000002044 109.0
PYH2_k127_2051164_12 PFAM TadE family protein - - - 0.00000000000436 72.0
PYH2_k127_2051164_13 PFAM TadE family protein - - - 0.00000000001513 71.0
PYH2_k127_2051164_14 PFAM TadE family protein - - - 0.000000009342 63.0
PYH2_k127_2051164_15 Rhs Family - - - 0.0000004844 61.0
PYH2_k127_2051164_16 Rhs Family - - - 0.000001134 60.0
PYH2_k127_2051164_17 TadE-like protein - - - 0.000002973 57.0
PYH2_k127_2051164_18 peptidyl-tyrosine sulfation - - - 0.0005777 51.0
PYH2_k127_2051164_19 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0007058 43.0
PYH2_k127_2051164_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 396.0
PYH2_k127_2051164_3 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 392.0
PYH2_k127_2051164_4 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 322.0
PYH2_k127_2051164_5 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 319.0
PYH2_k127_2051164_6 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 304.0
PYH2_k127_2051164_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000003392 194.0
PYH2_k127_2051164_8 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000004212 159.0
PYH2_k127_2051164_9 Putative TM nitroreductase - - - 0.0000000000000000000000000000000233 133.0
PYH2_k127_2052928_0 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 480.0
PYH2_k127_2052928_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 333.0
PYH2_k127_2052928_10 Tetratricopeptide repeat - - - 0.000008955 54.0
PYH2_k127_2052928_2 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
PYH2_k127_2052928_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000009918 230.0
PYH2_k127_2052928_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000009241 146.0
PYH2_k127_2052928_5 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000003806 134.0
PYH2_k127_2052928_6 GAF domain - - - 0.00000000000000000000000000000007594 136.0
PYH2_k127_2052928_7 - - - - 0.0000000009089 69.0
PYH2_k127_2052928_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000005422 63.0
PYH2_k127_2052928_9 Transcriptional regulator - - - 0.000003179 53.0
PYH2_k127_2099934_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.182e-207 657.0
PYH2_k127_2099934_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 550.0
PYH2_k127_2099934_2 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 415.0
PYH2_k127_2099934_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000001622 163.0
PYH2_k127_2099934_4 acid phosphatase activity - - - 0.000000000000000000000000000000000008086 146.0
PYH2_k127_2099934_5 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000008576 123.0
PYH2_k127_2099934_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000001162 104.0
PYH2_k127_2099934_8 - - - - 0.00000000000000007252 85.0
PYH2_k127_2099934_9 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000000000000002371 86.0
PYH2_k127_210543_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 463.0
PYH2_k127_210543_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 422.0
PYH2_k127_210543_2 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 352.0
PYH2_k127_210543_3 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001095 264.0
PYH2_k127_210543_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000558 236.0
PYH2_k127_210543_5 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000001206 154.0
PYH2_k127_210543_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000002875 54.0
PYH2_k127_2118342_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 8.786e-232 726.0
PYH2_k127_2118342_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 376.0
PYH2_k127_2118342_10 Putative zinc-finger - - - 0.0000000000000000000002335 111.0
PYH2_k127_2118342_11 sh3 domain protein K01448 - 3.5.1.28 0.0000006007 57.0
PYH2_k127_2118342_12 Glycosyl transferase, family 2 - - - 0.0000168 47.0
PYH2_k127_2118342_13 Involved in the tonB-independent uptake of proteins K03641 - - 0.000122 50.0
PYH2_k127_2118342_14 Na channel or K07150 - - 0.0001548 46.0
PYH2_k127_2118342_15 Involved in the TonB-independent uptake of proteins K03641 - - 0.0001721 50.0
PYH2_k127_2118342_2 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 374.0
PYH2_k127_2118342_3 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 370.0
PYH2_k127_2118342_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 336.0
PYH2_k127_2118342_5 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000004233 228.0
PYH2_k127_2118342_6 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000002138 226.0
PYH2_k127_2118342_7 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000006706 154.0
PYH2_k127_2118342_8 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000453 124.0
PYH2_k127_2118342_9 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000003215 129.0
PYH2_k127_2120453_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 395.0
PYH2_k127_2120453_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004406 293.0
PYH2_k127_2120453_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
PYH2_k127_2120453_3 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001094 256.0
PYH2_k127_2120453_4 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000001197 239.0
PYH2_k127_2120453_5 Glyco_18 - - - 0.00000000000000000000000000000000000000000000000000000000000001174 229.0
PYH2_k127_2120453_6 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000009877 108.0
PYH2_k127_2120453_7 Protein of unknown function (DUF1232) - - - 0.000000004323 61.0
PYH2_k127_2130554_0 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 567.0
PYH2_k127_2130554_1 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 345.0
PYH2_k127_2130554_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 300.0
PYH2_k127_2130554_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000003555 234.0
PYH2_k127_2130554_4 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000002633 209.0
PYH2_k127_2130554_5 MmgE/PrpD family - - - 0.000000000000000000000001174 110.0
PYH2_k127_2130554_6 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000006596 87.0
PYH2_k127_2156379_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.299e-213 677.0
PYH2_k127_2156379_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 532.0
PYH2_k127_2156379_10 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000001164 143.0
PYH2_k127_2156379_11 acetyltransferase K03826 - - 0.00000000000000000000000000000006986 130.0
PYH2_k127_2156379_12 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000505 137.0
PYH2_k127_2156379_13 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000001001 126.0
PYH2_k127_2156379_14 Protein of unknown function (DUF2723) K14340 - - 0.00000000000000000000000002131 126.0
PYH2_k127_2156379_15 Helix-turn-helix domain - - - 0.0000000002837 72.0
PYH2_k127_2156379_16 Auxin binding protein - - - 0.0000001315 59.0
PYH2_k127_2156379_2 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 432.0
PYH2_k127_2156379_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 409.0
PYH2_k127_2156379_4 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 397.0
PYH2_k127_2156379_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 367.0
PYH2_k127_2156379_6 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 367.0
PYH2_k127_2156379_7 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009528 247.0
PYH2_k127_2156379_8 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001827 220.0
PYH2_k127_2156379_9 molybdenum cofactor - - - 0.0000000000000000000000000000000000000000000000000000001301 199.0
PYH2_k127_2163025_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 531.0
PYH2_k127_2181063_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 584.0
PYH2_k127_2181063_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 447.0
PYH2_k127_2181063_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000002362 63.0
PYH2_k127_2192808_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 531.0
PYH2_k127_2192808_1 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 488.0
PYH2_k127_2192808_10 23S rRNA-intervening sequence protein - - - 0.00000000002762 68.0
PYH2_k127_2192808_11 23S rRNA-intervening sequence protein - - - 0.00000000152 60.0
PYH2_k127_2192808_12 S23 ribosomal protein - - - 0.000000007235 59.0
PYH2_k127_2192808_13 Collagen triple helix repeat - - - 0.0007338 47.0
PYH2_k127_2192808_2 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 346.0
PYH2_k127_2192808_3 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 340.0
PYH2_k127_2192808_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 323.0
PYH2_k127_2192808_5 Transposase K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 305.0
PYH2_k127_2192808_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 268.0
PYH2_k127_2192808_7 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002 258.0
PYH2_k127_2192808_8 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000003303 230.0
PYH2_k127_2192808_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000001717 200.0
PYH2_k127_221128_0 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 4.511e-304 945.0
PYH2_k127_221128_1 Belongs to the UPF0441 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 371.0
PYH2_k127_221128_2 COG1404 Subtilisin-like serine proteases K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 346.0
PYH2_k127_2213171_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.415e-208 702.0
PYH2_k127_2213171_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 511.0
PYH2_k127_2213171_10 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001572 265.0
PYH2_k127_2213171_11 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001139 267.0
PYH2_k127_2213171_12 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 263.0
PYH2_k127_2213171_13 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004294 247.0
PYH2_k127_2213171_14 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003111 248.0
PYH2_k127_2213171_15 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000008391 250.0
PYH2_k127_2213171_16 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000003346 217.0
PYH2_k127_2213171_17 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000002275 200.0
PYH2_k127_2213171_18 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000264 206.0
PYH2_k127_2213171_19 - - - - 0.0000000000000000000000000000000000000000000000915 181.0
PYH2_k127_2213171_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 495.0
PYH2_k127_2213171_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000009379 169.0
PYH2_k127_2213171_21 Phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000000000000000000000001564 154.0
PYH2_k127_2213171_22 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000001588 120.0
PYH2_k127_2213171_23 TOBE domain - - - 0.0000000000000000009435 88.0
PYH2_k127_2213171_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 482.0
PYH2_k127_2213171_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 443.0
PYH2_k127_2213171_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 402.0
PYH2_k127_2213171_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 372.0
PYH2_k127_2213171_7 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 352.0
PYH2_k127_2213171_8 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 316.0
PYH2_k127_2213171_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008382 272.0
PYH2_k127_2221019_0 glucan 1,4-alpha-glucosidase activity - - - 9.221e-249 785.0
PYH2_k127_2221019_1 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 458.0
PYH2_k127_2221019_2 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 461.0
PYH2_k127_2221019_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 449.0
PYH2_k127_2221019_4 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 422.0
PYH2_k127_2221019_5 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway K00068,K18124,K18125 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005515,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0046872,GO:0046914,GO:0046983,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.140,1.1.1.359,1.1.1.360 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 339.0
PYH2_k127_2221019_6 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
PYH2_k127_2221019_7 AMP binding - - - 0.000000000000000000000000000000001238 136.0
PYH2_k127_2221019_8 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000004567 118.0
PYH2_k127_2221019_9 ThiS family K03636 - - 0.00000000000000000003489 94.0
PYH2_k127_2246150_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000001611 83.0
PYH2_k127_2263613_0 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000002155 205.0
PYH2_k127_2263613_2 Domain of unknown function (DUF2088) - - - 0.0000000000000003939 82.0
PYH2_k127_2263613_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0001689 46.0
PYH2_k127_22779_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.596e-206 647.0
PYH2_k127_22779_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 266.0
PYH2_k127_22779_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003041 261.0
PYH2_k127_22779_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000036 205.0
PYH2_k127_22779_4 Ribosomal protein L33 K02913 - - 0.00000000000000001226 83.0
PYH2_k127_22779_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000194 59.0
PYH2_k127_2278329_0 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 428.0
PYH2_k127_2278329_1 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 321.0
PYH2_k127_2278329_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000001483 206.0
PYH2_k127_2278329_3 - - - - 0.0000000003219 67.0
PYH2_k127_2278329_4 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.00000009794 66.0
PYH2_k127_2282403_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 607.0
PYH2_k127_2282403_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 507.0
PYH2_k127_2282403_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000004541 222.0
PYH2_k127_2282403_11 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000005143 181.0
PYH2_k127_2282403_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001356 149.0
PYH2_k127_2282403_13 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000002381 138.0
PYH2_k127_2282403_14 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000009344 125.0
PYH2_k127_2282403_16 ABC transporter substrate binding protein K01989 - - 0.00000000000001927 77.0
PYH2_k127_2282403_17 ABC transporter substrate binding protein K01989 - - 0.000000000001688 75.0
PYH2_k127_2282403_18 Response regulator receiver - - - 0.00000000005674 72.0
PYH2_k127_2282403_19 transposase and inactivated derivatives, IS30 family - - - 0.00001962 50.0
PYH2_k127_2282403_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 475.0
PYH2_k127_2282403_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 422.0
PYH2_k127_2282403_4 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
PYH2_k127_2282403_5 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 345.0
PYH2_k127_2282403_6 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 325.0
PYH2_k127_2282403_7 PFAM NMT1 THI5 like domain protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 286.0
PYH2_k127_2282403_8 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000524 252.0
PYH2_k127_2282403_9 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003454 226.0
PYH2_k127_2282548_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 530.0
PYH2_k127_2282548_1 SMART Nucleotide binding protein, PINc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 379.0
PYH2_k127_2282548_10 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.000006427 58.0
PYH2_k127_2282548_11 Putative Flp pilus-assembly TadE/G-like - - - 0.0002051 53.0
PYH2_k127_2282548_12 translation initiation factor activity - - - 0.0009931 51.0
PYH2_k127_2282548_2 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 350.0
PYH2_k127_2282548_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000063 276.0
PYH2_k127_2282548_4 belongs to the sigma-70 factor family, ECF subfamily - - - 0.0000000000000000000000000000003526 130.0
PYH2_k127_2282548_5 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000006278 87.0
PYH2_k127_2282548_6 PFAM TadE family protein - - - 0.00000000001422 70.0
PYH2_k127_2282548_8 PFAM TadE family protein - - - 0.000000001414 65.0
PYH2_k127_2282548_9 Tfp pilus assembly protein FimV - - - 0.00000235 60.0
PYH2_k127_2304997_0 integral membrane protein - - - 0.00000000000000000002849 97.0
PYH2_k127_2304997_1 - - - - 0.0000000007944 60.0
PYH2_k127_2304997_2 YtxH-like protein - - - 0.000000147 58.0
PYH2_k127_2342741_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 396.0
PYH2_k127_2342741_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001605 270.0
PYH2_k127_2342741_2 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000002152 211.0
PYH2_k127_2343776_0 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 449.0
PYH2_k127_2343776_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000001796 249.0
PYH2_k127_2343776_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000299 229.0
PYH2_k127_2343776_3 PFAM Abortive infection protein - - - 0.000000000000000000000000000000000000000000000000000004565 199.0
PYH2_k127_2347786_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 398.0
PYH2_k127_2347786_1 - - - - 0.0000000000000004903 80.0
PYH2_k127_2392056_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 7.697e-241 774.0
PYH2_k127_2392056_1 PFAM Peptidase family M20 M25 M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 572.0
PYH2_k127_2392056_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 474.0
PYH2_k127_2392056_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 466.0
PYH2_k127_2392056_4 - - - - 0.0000000001433 61.0
PYH2_k127_2392056_5 Periplasmic copper-binding protein (NosD) - - - 0.0000003409 63.0
PYH2_k127_241929_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.241e-211 676.0
PYH2_k127_241929_1 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 506.0
PYH2_k127_241929_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 377.0
PYH2_k127_241929_3 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000009488 128.0
PYH2_k127_2421363_0 Belongs to the carbamoyltransferase HypF family K04656 - - 7.515e-259 820.0
PYH2_k127_2421363_1 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 534.0
PYH2_k127_2421363_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 430.0
PYH2_k127_2421363_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000004807 246.0
PYH2_k127_2421363_4 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000007797 108.0
PYH2_k127_2421363_5 Belongs to the 'phage' integrase family K04763 - - 0.0000000000957 67.0
PYH2_k127_2424997_0 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 1.046e-277 877.0
PYH2_k127_2424997_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.234e-231 731.0
PYH2_k127_2424997_10 - - - - 0.00000000000000000000000000000000000000000000000000001311 203.0
PYH2_k127_2424997_11 - - - - 0.000000000000000000000000000000000000000000000931 176.0
PYH2_k127_2424997_12 YHYH protein - - - 0.00000000000000000000000000000000000000000669 161.0
PYH2_k127_2424997_13 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000006242 155.0
PYH2_k127_2424997_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000001311 139.0
PYH2_k127_2424997_15 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000006759 85.0
PYH2_k127_2424997_16 Putative methyltransferase K00564 - 2.1.1.172 0.000000000004334 75.0
PYH2_k127_2424997_17 FES K10773 - 4.2.99.18 0.00000000001258 67.0
PYH2_k127_2424997_18 Tetratricopeptide repeat - - - 0.000000009501 66.0
PYH2_k127_2424997_19 Transposase for insertion sequence element IS1086 K07482 - - 0.0000005753 52.0
PYH2_k127_2424997_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 433.0
PYH2_k127_2424997_20 EndoIII-related endonuclease K10773 - 4.2.99.18 0.00001795 48.0
PYH2_k127_2424997_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 428.0
PYH2_k127_2424997_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 372.0
PYH2_k127_2424997_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 334.0
PYH2_k127_2424997_6 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 336.0
PYH2_k127_2424997_7 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 323.0
PYH2_k127_2424997_8 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 315.0
PYH2_k127_2424997_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133,5.1.3.13,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 306.0
PYH2_k127_2440205_0 PFAM ABC transporter transmembrane region K06147 - - 1.91e-284 887.0
PYH2_k127_2440205_1 ABC transporter, ATP-binding protein K06147 - - 0.000000000000000000000000000000000000000000000000000000000000004099 218.0
PYH2_k127_2440205_2 Biotin-lipoyl like K01993,K16922 - - 0.00000000006131 71.0
PYH2_k127_2456752_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 336.0
PYH2_k127_2456752_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 306.0
PYH2_k127_2456752_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 316.0
PYH2_k127_2456752_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009079 279.0
PYH2_k127_2456752_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001925 279.0
PYH2_k127_2456752_5 transport systems K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007896 273.0
PYH2_k127_2456752_6 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009421 282.0
PYH2_k127_2456752_7 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000006885 247.0
PYH2_k127_2456752_8 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000008744 231.0
PYH2_k127_2456752_9 Major facilitator superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000001136 93.0
PYH2_k127_2500045_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 3.227e-282 882.0
PYH2_k127_2500045_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.143e-249 782.0
PYH2_k127_2500045_10 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
PYH2_k127_2500045_11 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000004115 238.0
PYH2_k127_2500045_12 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
PYH2_k127_2500045_13 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
PYH2_k127_2500045_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000002728 219.0
PYH2_k127_2500045_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000004062 196.0
PYH2_k127_2500045_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000001344 164.0
PYH2_k127_2500045_17 Peptidase M50 - - - 0.0000000000000000000000000000000000163 144.0
PYH2_k127_2500045_18 Chorismate mutase type I K00945,K06208 GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 2.7.4.25,5.4.99.5 0.0000000000000000000000000000000001611 136.0
PYH2_k127_2500045_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000001427 130.0
PYH2_k127_2500045_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 562.0
PYH2_k127_2500045_20 HYR domain K03286 - - 0.0000000000000000000000000000002257 143.0
PYH2_k127_2500045_21 Hep Hag repeat protein - - - 0.000000000000000000738 102.0
PYH2_k127_2500045_22 Bacterial protein of unknown function (DUF922) - - - 0.0000000002632 71.0
PYH2_k127_2500045_23 Belongs to the ompA family K03640 - - 0.000005287 59.0
PYH2_k127_2500045_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 552.0
PYH2_k127_2500045_4 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 476.0
PYH2_k127_2500045_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 350.0
PYH2_k127_2500045_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000075 281.0
PYH2_k127_2500045_7 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001768 267.0
PYH2_k127_2500045_8 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000006473 266.0
PYH2_k127_2500045_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 257.0
PYH2_k127_2502391_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002802 308.0
PYH2_k127_2502391_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000007426 180.0
PYH2_k127_2502391_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000001242 92.0
PYH2_k127_2502391_3 - - - - 0.000000001322 70.0
PYH2_k127_2502391_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000002338 69.0
PYH2_k127_2509297_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.822e-251 785.0
PYH2_k127_2509297_1 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 481.0
PYH2_k127_2509297_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 388.0
PYH2_k127_2509297_3 - - - - 0.00000000000000000000000000000000000000000000002452 181.0
PYH2_k127_2515816_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1371.0
PYH2_k127_2515816_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 490.0
PYH2_k127_2515816_2 Peptidase family M20/M25/M40 K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003403 283.0
PYH2_k127_2515816_3 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006454 275.0
PYH2_k127_2515816_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000008098 223.0
PYH2_k127_2515816_5 PFAM Divergent PAP2 family K09775 - - 0.00000000000000000000000000000000000000007099 156.0
PYH2_k127_2515816_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000004135 117.0
PYH2_k127_2515816_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000007211 60.0
PYH2_k127_2515816_8 MacB-like periplasmic core domain K02004 - - 0.000003034 53.0
PYH2_k127_253063_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 2.389e-232 728.0
PYH2_k127_253063_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 602.0
PYH2_k127_253063_10 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 319.0
PYH2_k127_253063_11 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002587 286.0
PYH2_k127_253063_12 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006123 297.0
PYH2_k127_253063_13 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002198 269.0
PYH2_k127_253063_14 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
PYH2_k127_253063_15 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000008299 251.0
PYH2_k127_253063_16 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001452 235.0
PYH2_k127_253063_17 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000672 213.0
PYH2_k127_253063_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001996 194.0
PYH2_k127_253063_19 - - - - 0.000000000000000000000000000000000000000000000000003397 191.0
PYH2_k127_253063_2 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 621.0
PYH2_k127_253063_20 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000001406 177.0
PYH2_k127_253063_21 Oxidoreductase - - - 0.00000000000000000000000000000000000008006 156.0
PYH2_k127_253063_22 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000009164 147.0
PYH2_k127_253063_23 4Fe-4S binding domain - - - 0.000000000000000000000000000000005328 129.0
PYH2_k127_253063_24 Dimerisation domain - - - 0.00000000000000000000000000005952 130.0
PYH2_k127_253063_25 Pfam:DUF422 - - - 0.0000000000000000000000003312 116.0
PYH2_k127_253063_26 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000002274 107.0
PYH2_k127_253063_27 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000001098 105.0
PYH2_k127_253063_28 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.0000000000002965 77.0
PYH2_k127_253063_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 611.0
PYH2_k127_253063_30 DinB family - - - 0.00000000005178 70.0
PYH2_k127_253063_31 phosphorelay signal transduction system - - - 0.000000006541 62.0
PYH2_k127_253063_32 CAAX protease self-immunity K01266,K07052 - 3.4.11.19 0.0000002367 62.0
PYH2_k127_253063_33 membrane - - - 0.00001043 49.0
PYH2_k127_253063_4 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 516.0
PYH2_k127_253063_5 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 484.0
PYH2_k127_253063_6 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 462.0
PYH2_k127_253063_7 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 453.0
PYH2_k127_253063_8 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 432.0
PYH2_k127_253063_9 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 362.0
PYH2_k127_2548690_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.92e-228 718.0
PYH2_k127_2548690_1 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 2.855e-220 694.0
PYH2_k127_2548690_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 425.0
PYH2_k127_2548690_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 391.0
PYH2_k127_2548690_4 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000004135 191.0
PYH2_k127_2548690_5 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000005627 179.0
PYH2_k127_2548690_6 AMP binding - - - 0.000000000000000000000000000000000211 139.0
PYH2_k127_2548690_7 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000000008052 116.0
PYH2_k127_2548690_8 TfoX N-terminal domain - - - 0.00000001982 61.0
PYH2_k127_2566273_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.464e-296 915.0
PYH2_k127_2566273_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.419e-263 841.0
PYH2_k127_2566273_10 Iron ABC transporter substrate-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009242 260.0
PYH2_k127_2566273_11 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.00000000000000000000000000000000000000000000000000000000000003492 218.0
PYH2_k127_2566273_12 Haloacid dehalogenase-like hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000004444 194.0
PYH2_k127_2566273_13 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000001383 160.0
PYH2_k127_2566273_14 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000001453 146.0
PYH2_k127_2566273_15 oxidation-reduction process - - - 0.000000000000000000000000000000000001762 145.0
PYH2_k127_2566273_16 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000103 138.0
PYH2_k127_2566273_17 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000002691 119.0
PYH2_k127_2566273_18 23S rRNA-intervening sequence protein - - - 0.000000000001273 72.0
PYH2_k127_2566273_19 Mg chelatase-like protein K07391 - - 0.000000002213 61.0
PYH2_k127_2566273_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 7.047e-238 757.0
PYH2_k127_2566273_20 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.000000387 59.0
PYH2_k127_2566273_3 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 532.0
PYH2_k127_2566273_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 465.0
PYH2_k127_2566273_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 360.0
PYH2_k127_2566273_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
PYH2_k127_2566273_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 323.0
PYH2_k127_2566273_8 Abhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 303.0
PYH2_k127_2566273_9 ABC transporter substrate-binding protein PnrA-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007143 284.0
PYH2_k127_2599898_0 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002416 260.0
PYH2_k127_2599898_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
PYH2_k127_2599898_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002517 162.0
PYH2_k127_2599898_3 spore germination - - - 0.000000000000000000000000000003564 131.0
PYH2_k127_2599898_4 integral membrane protein - - - 0.0000000000000000000000006505 111.0
PYH2_k127_2599898_5 Tetratricopeptide repeat - - - 0.00000002145 64.0
PYH2_k127_2603553_0 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006465 258.0
PYH2_k127_2603553_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001604 253.0
PYH2_k127_2603553_2 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
PYH2_k127_2603553_3 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000281 183.0
PYH2_k127_2603553_4 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000000004511 152.0
PYH2_k127_2603553_5 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000002579 129.0
PYH2_k127_2659706_0 ggdef domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 537.0
PYH2_k127_2659706_1 PFAM Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000001321 105.0
PYH2_k127_2669643_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1092.0
PYH2_k127_2669643_1 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 319.0
PYH2_k127_2669643_10 TIGRFAM polymorphic outer membrane protein - - - 0.0006148 46.0
PYH2_k127_2669643_2 4Fe-4S ferredoxin K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 295.0
PYH2_k127_2669643_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000003622 218.0
PYH2_k127_2669643_4 catechol 1,2-dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000004494 216.0
PYH2_k127_2669643_5 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000006473 180.0
PYH2_k127_2669643_6 Parallel beta-helix repeats K12287 - - 0.0000000000000000000000000000000000000000000009344 186.0
PYH2_k127_2669643_7 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000001718 140.0
PYH2_k127_2669643_9 Cellulose biosynthesis protein BcsQ K02282 - - 0.0000000000000000007344 99.0
PYH2_k127_267041_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 478.0
PYH2_k127_267041_1 transcription factor binding - - - 0.00000000000005313 75.0
PYH2_k127_2678363_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
PYH2_k127_2678363_1 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.0000000000000000002552 102.0
PYH2_k127_2678363_2 Cytochrome c-type protein K15876 - - 0.0001997 51.0
PYH2_k127_2705590_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 372.0
PYH2_k127_2705590_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004458 256.0
PYH2_k127_2705590_2 sterol carrier protein - - - 0.000003131 58.0
PYH2_k127_2718798_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000004464 245.0
PYH2_k127_2718798_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000006427 210.0
PYH2_k127_2718798_2 Type III restriction protein res subunit K10843 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001109 211.0
PYH2_k127_2718798_3 4Fe-4S dicluster domain - - - 0.00000000000000000768 89.0
PYH2_k127_2731791_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 7.228e-207 662.0
PYH2_k127_2731791_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 474.0
PYH2_k127_2731791_2 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008864 249.0
PYH2_k127_2731791_3 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000006284 251.0
PYH2_k127_2731791_4 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000001758 181.0
PYH2_k127_2731791_5 Double zinc ribbon - - - 0.000000000000000000000000000000000000000001264 161.0
PYH2_k127_2731791_6 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.0000000000000000000000000000000000000002543 158.0
PYH2_k127_2731791_7 - - - - 0.000000000000000027 94.0
PYH2_k127_2731791_8 - - - - 0.0000000005207 63.0
PYH2_k127_2762945_0 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001858 268.0
PYH2_k127_2762945_1 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000002734 169.0
PYH2_k127_2762945_2 Psort location Cytoplasmic, score K22227 - - 0.000000000000000000000000001082 123.0
PYH2_k127_2762945_3 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000004058 109.0
PYH2_k127_2762945_4 - - - - 0.0000000000000001278 90.0
PYH2_k127_2762945_5 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000006275 54.0
PYH2_k127_277991_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.03e-209 664.0
PYH2_k127_277991_1 PFAM tRNA synthetase class II (D K and N), nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 584.0
PYH2_k127_277991_10 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000537 98.0
PYH2_k127_277991_11 Tetratricopeptide repeat - - - 0.000000000000000001097 100.0
PYH2_k127_277991_12 - - - - 0.0000000000000001358 83.0
PYH2_k127_277991_13 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000002245 88.0
PYH2_k127_277991_14 - - - - 0.00000000000007962 77.0
PYH2_k127_277991_15 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000003174 70.0
PYH2_k127_277991_16 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000001235 73.0
PYH2_k127_277991_17 Tetratricopeptide TPR_2 repeat protein - - - 0.0000005464 55.0
PYH2_k127_277991_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 556.0
PYH2_k127_277991_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 354.0
PYH2_k127_277991_4 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 330.0
PYH2_k127_277991_5 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000004917 224.0
PYH2_k127_277991_6 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000008954 184.0
PYH2_k127_277991_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000002102 166.0
PYH2_k127_277991_8 - - - - 0.0000000000000000000000000000000000357 145.0
PYH2_k127_277991_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000006973 130.0
PYH2_k127_2786525_0 Elongation factor SelB, winged helix K03833 - - 5.534e-194 623.0
PYH2_k127_2786525_1 spermidine synthase activity K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 450.0
PYH2_k127_2786525_2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000006635 198.0
PYH2_k127_2786525_3 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000000000000000005371 157.0
PYH2_k127_2786525_4 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000001653 154.0
PYH2_k127_2786525_5 Protein of unknown function (DUF1461) - - - 0.00000000000000000000003164 108.0
PYH2_k127_2786525_6 Integrase core domain - - - 0.000000000000004509 76.0
PYH2_k127_2786525_8 Pfam Integrase core domain - - - 0.00002978 52.0
PYH2_k127_2792223_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 504.0
PYH2_k127_2792223_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 464.0
PYH2_k127_2792223_10 Protein of unknown function (DUF1232) - - - 0.0000000003406 67.0
PYH2_k127_2792223_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 456.0
PYH2_k127_2792223_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 362.0
PYH2_k127_2792223_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 345.0
PYH2_k127_2792223_5 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
PYH2_k127_2792223_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000007663 151.0
PYH2_k127_2792223_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000007505 138.0
PYH2_k127_2792223_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000576 125.0
PYH2_k127_2792223_9 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01153,K06042,K22491 - 3.1.21.3,5.4.99.60,5.4.99.61 0.0000000000000006165 85.0
PYH2_k127_2803258_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.672e-219 688.0
PYH2_k127_2803258_1 Pyridine nucleotide-disulphide oxidoreductase K00362,K22405 - 1.6.3.4,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 387.0
PYH2_k127_2803258_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 382.0
PYH2_k127_2803258_3 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 298.0
PYH2_k127_2803258_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 265.0
PYH2_k127_2803258_5 - - - - 0.0000001286 56.0
PYH2_k127_2803258_6 4Fe-4S double cluster binding domain - - - 0.0000879 45.0
PYH2_k127_2803258_7 binding domain protein - - - 0.0003443 44.0
PYH2_k127_2803935_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 4.999e-214 672.0
PYH2_k127_2803935_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001159 231.0
PYH2_k127_2803935_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001155 209.0
PYH2_k127_2804119_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1233.0
PYH2_k127_2804119_1 amidase activity K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 472.0
PYH2_k127_2804119_2 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 334.0
PYH2_k127_2804119_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002261 283.0
PYH2_k127_2804119_4 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004542 261.0
PYH2_k127_2804119_5 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000000005003 189.0
PYH2_k127_2810826_0 Oligopeptidase F K08602 - - 1.388e-244 769.0
PYH2_k127_2810826_1 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 593.0
PYH2_k127_2810826_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 292.0
PYH2_k127_2810826_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002482 285.0
PYH2_k127_2810826_12 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002327 278.0
PYH2_k127_2810826_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000001257 248.0
PYH2_k127_2810826_14 MFS_1 like family K08151,K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000284 241.0
PYH2_k127_2810826_15 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000000000000000000000000000000000000003695 225.0
PYH2_k127_2810826_16 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
PYH2_k127_2810826_17 ATPase involved in DNA repair K03546 - - 0.000000000000000000000000000000000000000000000000000000001101 229.0
PYH2_k127_2810826_18 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000000000000006375 182.0
PYH2_k127_2810826_19 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000003962 183.0
PYH2_k127_2810826_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 516.0
PYH2_k127_2810826_20 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000001232 181.0
PYH2_k127_2810826_21 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000005186 152.0
PYH2_k127_2810826_22 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000001759 144.0
PYH2_k127_2810826_23 Transcriptional regulator - - - 0.0000000000000000000000000000002005 128.0
PYH2_k127_2810826_24 mitochondrial translation K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000003693 111.0
PYH2_k127_2810826_25 - - - - 0.00000000000000000000000006425 109.0
PYH2_k127_2810826_26 DoxX-like family - - - 0.000000000000000000000000331 111.0
PYH2_k127_2810826_27 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000002182 94.0
PYH2_k127_2810826_28 Belongs to the UPF0109 family K06960 - - 0.000000000000000002977 89.0
PYH2_k127_2810826_29 regulatory protein, FmdB family - - - 0.00000000000000002863 85.0
PYH2_k127_2810826_3 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 391.0
PYH2_k127_2810826_30 F420H(2)-dependent quinone reductase - - - 0.00000000000000005641 86.0
PYH2_k127_2810826_31 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000001194 86.0
PYH2_k127_2810826_33 - - - - 0.000006211 52.0
PYH2_k127_2810826_4 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 381.0
PYH2_k127_2810826_5 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 358.0
PYH2_k127_2810826_6 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 340.0
PYH2_k127_2810826_7 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 332.0
PYH2_k127_2810826_8 PFAM Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
PYH2_k127_2810826_9 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 323.0
PYH2_k127_2818543_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1104.0
PYH2_k127_2818543_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1026.0
PYH2_k127_2818543_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000002277 179.0
PYH2_k127_2818543_11 NAD binding domain of 6-phosphogluconate dehydrogenase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000008872 179.0
PYH2_k127_2818543_12 extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000003565 160.0
PYH2_k127_2818543_13 Smr domain - - - 0.00000000000000000000000000000000007104 135.0
PYH2_k127_2818543_14 Protein of unknown function (DUF3592) - - - 0.000000000000000000000000000000003704 140.0
PYH2_k127_2818543_15 NYN domain - - - 0.00000000000000000002073 102.0
PYH2_k127_2818543_16 Bacterial pre-peptidase C-terminal domain - - - 0.0000000000000003535 91.0
PYH2_k127_2818543_17 PFAM ABC transporter K01990 - - 0.0000000000006027 71.0
PYH2_k127_2818543_18 coenzyme binding K07071 - - 0.0000000001082 65.0
PYH2_k127_2818543_19 Protein of unknown function (DUF664) - - - 0.0000000002976 68.0
PYH2_k127_2818543_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 5.134e-241 766.0
PYH2_k127_2818543_20 serine-type aminopeptidase activity K14475 - - 0.0000002264 57.0
PYH2_k127_2818543_21 - - - - 0.0005763 44.0
PYH2_k127_2818543_3 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 8.927e-214 672.0
PYH2_k127_2818543_4 PHP domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 542.0
PYH2_k127_2818543_5 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 438.0
PYH2_k127_2818543_6 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 399.0
PYH2_k127_2818543_7 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 294.0
PYH2_k127_2818543_8 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000002394 211.0
PYH2_k127_2818543_9 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000407 184.0
PYH2_k127_2822024_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 8.241e-238 751.0
PYH2_k127_2822024_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 6.817e-203 645.0
PYH2_k127_2822024_10 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 322.0
PYH2_k127_2822024_11 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
PYH2_k127_2822024_12 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 312.0
PYH2_k127_2822024_13 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000015 266.0
PYH2_k127_2822024_14 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000005264 184.0
PYH2_k127_2822024_15 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000000000000000000000000000000000000000008852 168.0
PYH2_k127_2822024_16 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000009587 157.0
PYH2_k127_2822024_17 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000546 150.0
PYH2_k127_2822024_18 transcriptional - - - 0.000000000000000000000000000000000009459 147.0
PYH2_k127_2822024_19 PFAM CBS domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000001243 77.0
PYH2_k127_2822024_2 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 567.0
PYH2_k127_2822024_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 541.0
PYH2_k127_2822024_4 nitrite transmembrane transporter activity K02532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 415.0
PYH2_k127_2822024_5 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 402.0
PYH2_k127_2822024_6 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336,K05299 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 396.0
PYH2_k127_2822024_7 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 390.0
PYH2_k127_2822024_8 methenyltetrahydrofolate cyclohydrolase activity K00288 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019219,GO:0019222,GO:0019238,GO:0019752,GO:0031323,GO:0034641,GO:0042558,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044030,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046653,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051186,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9,6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 376.0
PYH2_k127_2822024_9 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 373.0
PYH2_k127_2841625_0 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 387.0
PYH2_k127_2841625_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000008656 202.0
PYH2_k127_2841625_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000003344 191.0
PYH2_k127_2841625_3 Domain of unknown function (DUF4342) - - - 0.000000000000000003072 87.0
PYH2_k127_2864466_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 5.31e-214 693.0
PYH2_k127_2864466_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 550.0
PYH2_k127_2864466_10 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000005638 271.0
PYH2_k127_2864466_11 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000001618 258.0
PYH2_k127_2864466_12 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004051 253.0
PYH2_k127_2864466_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000004329 222.0
PYH2_k127_2864466_14 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000008858 163.0
PYH2_k127_2864466_15 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000000004978 157.0
PYH2_k127_2864466_16 UbiC transcription regulator-associated domain protein K03710 - - 0.00000000000000000000000000000000000000007973 160.0
PYH2_k127_2864466_17 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000007057 132.0
PYH2_k127_2864466_18 maltose binding K02027,K15770 - - 0.0000000000000000000000000468 122.0
PYH2_k127_2864466_19 JAB/MPN domain K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00000000000000000000002762 106.0
PYH2_k127_2864466_2 2-oxoisovalerate dehydrogenase K00167,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 437.0
PYH2_k127_2864466_20 23S rRNA-intervening sequence protein - - - 0.0000000000000000001198 92.0
PYH2_k127_2864466_21 SLBB domain K02237 - - 0.0000000000797 71.0
PYH2_k127_2864466_3 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 421.0
PYH2_k127_2864466_4 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 426.0
PYH2_k127_2864466_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 419.0
PYH2_k127_2864466_6 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 387.0
PYH2_k127_2864466_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 327.0
PYH2_k127_2864466_8 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 290.0
PYH2_k127_2864466_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000001957 273.0
PYH2_k127_2868410_0 PFAM Enoyl-CoA hydratase isomerase K07516 - 1.1.1.35 6.121e-235 747.0
PYH2_k127_2868410_1 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000004398 76.0
PYH2_k127_2868410_2 Lamin Tail Domain - - - 0.0000000007098 67.0
PYH2_k127_2910283_0 PFAM fumarate lyase K01679 - 4.2.1.2 3.518e-217 683.0
PYH2_k127_2910283_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 423.0
PYH2_k127_2910283_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000773 173.0
PYH2_k127_2910283_3 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000001021 175.0
PYH2_k127_2910283_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000002576 74.0
PYH2_k127_2910283_5 PFAM Tetratricopeptide repeat - - - 0.0001854 49.0
PYH2_k127_2912663_0 2-dehydropantoate 2-reductase activity K00077,K01295 - 1.1.1.169,3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 463.0
PYH2_k127_2912663_1 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 347.0
PYH2_k127_2912663_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
PYH2_k127_2912663_3 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000004468 137.0
PYH2_k127_2928842_0 phosphatase K01083,K07004 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 418.0
PYH2_k127_2928842_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 366.0
PYH2_k127_2928842_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 287.0
PYH2_k127_2928842_3 CHRD domain - - - 0.0000000000000000000000000000000000000000001173 166.0
PYH2_k127_2928842_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05889,K12678 - 1.1.2.6 0.000000000000000000000000000000000000000005083 174.0
PYH2_k127_2928842_5 filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000005003 169.0
PYH2_k127_2928842_6 domain, Protein K21449 - - 0.0000000000000000000000000000000000000003117 164.0
PYH2_k127_2928842_7 pathogenesis K20276 - - 0.0000000000000000000000000000003267 124.0
PYH2_k127_2928842_8 - - - - 0.000000000000008424 83.0
PYH2_k127_2938713_0 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 3.065e-199 630.0
PYH2_k127_2938713_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 531.0
PYH2_k127_2938713_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 414.0
PYH2_k127_2938713_3 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 416.0
PYH2_k127_2938713_4 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 328.0
PYH2_k127_2938713_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007385 288.0
PYH2_k127_2938713_6 - K14340 - - 0.000000000000000000000000000000000000000000000000000000000005726 228.0
PYH2_k127_2938713_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.0000000000000000000005559 112.0
PYH2_k127_2938713_8 Helix-turn-helix of DDE superfamily endonuclease - - - 0.0000000000002179 78.0
PYH2_k127_2963842_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 461.0
PYH2_k127_2963842_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 421.0
PYH2_k127_2963842_10 - - - - 0.0000000000000000000003795 101.0
PYH2_k127_2963842_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000003966 86.0
PYH2_k127_2963842_12 PFAM regulatory protein LuxR - - - 0.00000001708 61.0
PYH2_k127_2963842_13 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000002232 60.0
PYH2_k127_2963842_14 - - - - 0.0001057 49.0
PYH2_k127_2963842_2 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 364.0
PYH2_k127_2963842_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000024 297.0
PYH2_k127_2963842_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001062 287.0
PYH2_k127_2963842_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003714 278.0
PYH2_k127_2963842_6 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000003265 210.0
PYH2_k127_2963842_7 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000009103 196.0
PYH2_k127_2963842_8 acetyltransferase - - - 0.00000000000000000000000000001317 128.0
PYH2_k127_2963842_9 - - - - 0.000000000000000000000000006763 116.0
PYH2_k127_2966426_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 330.0
PYH2_k127_2969174_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.235e-260 844.0
PYH2_k127_2969174_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 536.0
PYH2_k127_2969174_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0001746 44.0
PYH2_k127_2969174_11 Transposase DDE domain K07492 - - 0.000213 46.0
PYH2_k127_2969174_2 pyrroloquinoline quinone binding K01206,K01218 - 3.2.1.51,3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 402.0
PYH2_k127_2969174_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000117 181.0
PYH2_k127_2969174_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000001321 151.0
PYH2_k127_2969174_5 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.000000000000000000000000000004573 130.0
PYH2_k127_2969174_6 Belongs to the UPF0761 family K07058 - - 0.000000000000000000000331 108.0
PYH2_k127_2969174_7 HAD-hyrolase-like K07025 - - 0.0000000000000002767 85.0
PYH2_k127_2969174_8 Methyltransferase domain - - - 0.00000000003008 74.0
PYH2_k127_2969174_9 Belongs to the Nudix hydrolase family K12944 - - 0.000000002169 64.0
PYH2_k127_2972193_0 domain protein - - - 0.0000000000000000000000007529 113.0
PYH2_k127_2972193_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000002159 101.0
PYH2_k127_2972193_2 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000002958 106.0
PYH2_k127_3011202_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 505.0
PYH2_k127_3011202_1 Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues K01791,K08068 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576 3.2.1.183,5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 432.0
PYH2_k127_3011202_10 Belongs to the peptidase S8 family K12287 - - 0.000000000001243 78.0
PYH2_k127_3011202_11 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00001663 48.0
PYH2_k127_3011202_2 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 421.0
PYH2_k127_3011202_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 331.0
PYH2_k127_3011202_4 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 305.0
PYH2_k127_3011202_5 PFAM lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007918 255.0
PYH2_k127_3011202_6 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000005517 218.0
PYH2_k127_3011202_7 -O-antigen K13009,K18814 - - 0.0000000000000000000000000000000001177 150.0
PYH2_k127_3011202_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000001619 92.0
PYH2_k127_3011202_9 transferase activity, transferring glycosyl groups - - - 0.000000000000002759 83.0
PYH2_k127_3016330_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 553.0
PYH2_k127_3016330_1 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 383.0
PYH2_k127_3016330_2 PaaX-like protein K02616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003715 254.0
PYH2_k127_3016330_3 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000002059 123.0
PYH2_k127_3020801_0 xylan catabolic process K01181,K07004,K12548 GO:0005575,GO:0005576 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 470.0
PYH2_k127_3020801_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 411.0
PYH2_k127_3020801_2 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 339.0
PYH2_k127_3020801_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001328 259.0
PYH2_k127_3022723_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 534.0
PYH2_k127_3022723_1 Yip1 domain - - - 0.000000000000000000000000000000000000000503 157.0
PYH2_k127_3022723_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000008079 128.0
PYH2_k127_3022723_3 PFAM Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000001212 118.0
PYH2_k127_3034283_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.316e-300 958.0
PYH2_k127_3034283_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.177e-240 774.0
PYH2_k127_3034283_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 296.0
PYH2_k127_3034283_11 Belongs to the DapA family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002182 275.0
PYH2_k127_3034283_12 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000002167 218.0
PYH2_k127_3034283_13 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000005232 209.0
PYH2_k127_3034283_14 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000001418 200.0
PYH2_k127_3034283_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000003625 201.0
PYH2_k127_3034283_16 Cupin domain - - - 0.00000000000000000000000000000000000000000000000001855 182.0
PYH2_k127_3034283_17 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000003368 184.0
PYH2_k127_3034283_18 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000004152 172.0
PYH2_k127_3034283_19 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000001317 138.0
PYH2_k127_3034283_2 Bacterial protein of unknown function (DUF853) - - - 2.482e-211 668.0
PYH2_k127_3034283_20 - - - - 0.000000000000000000000000000000002399 144.0
PYH2_k127_3034283_21 ErfK ybiS ycfS ynhG family protein - - - 0.000000000001058 79.0
PYH2_k127_3034283_22 PLD-like domain - - - 0.0000000006653 69.0
PYH2_k127_3034283_23 - - - - 0.000000001218 67.0
PYH2_k127_3034283_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00001027 58.0
PYH2_k127_3034283_3 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 555.0
PYH2_k127_3034283_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 477.0
PYH2_k127_3034283_5 peptidase M42 family protein K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 379.0
PYH2_k127_3034283_6 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 353.0
PYH2_k127_3034283_7 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 352.0
PYH2_k127_3034283_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 343.0
PYH2_k127_3034283_9 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 349.0
PYH2_k127_30489_0 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 337.0
PYH2_k127_30489_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 312.0
PYH2_k127_30489_10 Cytochrome c - - - 0.00000000000009072 82.0
PYH2_k127_30489_11 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001722 64.0
PYH2_k127_30489_12 - - - - 0.00000002735 61.0
PYH2_k127_30489_2 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
PYH2_k127_30489_3 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000002872 211.0
PYH2_k127_30489_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003233 203.0
PYH2_k127_30489_5 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.00000000000000000000000000000000000000000000000000000256 199.0
PYH2_k127_30489_6 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000543 194.0
PYH2_k127_30489_7 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000001919 179.0
PYH2_k127_30489_8 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000005326 164.0
PYH2_k127_30489_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000003506 136.0
PYH2_k127_3061096_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 392.0
PYH2_k127_3061096_1 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
PYH2_k127_3061096_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000001564 208.0
PYH2_k127_3061096_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000355 192.0
PYH2_k127_3061096_4 MFS transporter - - - 0.000000000002159 79.0
PYH2_k127_3074453_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 346.0
PYH2_k127_3074453_1 ATP-dependent transcriptional regulator K03556 - - 0.000000000000000004156 94.0
PYH2_k127_3074453_2 Nad-dependent epimerase dehydratase - - - 0.0000000000001275 76.0
PYH2_k127_308146_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.291e-210 670.0
PYH2_k127_308146_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.376e-198 634.0
PYH2_k127_308146_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 342.0
PYH2_k127_308146_11 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 321.0
PYH2_k127_308146_12 Domain of unknown function (DUF4032) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002446 276.0
PYH2_k127_308146_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000003627 229.0
PYH2_k127_308146_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003791 224.0
PYH2_k127_308146_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000556 224.0
PYH2_k127_308146_16 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000003359 211.0
PYH2_k127_308146_17 - - - - 0.00000000000000000000000000000000000000000000000000001549 197.0
PYH2_k127_308146_18 - - - - 0.0000000000000000000000000000000000000000000000002316 180.0
PYH2_k127_308146_19 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000009308 163.0
PYH2_k127_308146_2 Amidohydrolase family - - - 4.093e-198 627.0
PYH2_k127_308146_20 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000004294 161.0
PYH2_k127_308146_21 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000003416 99.0
PYH2_k127_308146_22 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000721 102.0
PYH2_k127_308146_23 Psort location Cytoplasmic, score - - - 0.00000000000000000001795 100.0
PYH2_k127_308146_24 Domain of unknown function (DUF4203) - - - 0.0000000000000000000416 97.0
PYH2_k127_308146_25 - - - - 0.000000000000002371 82.0
PYH2_k127_308146_26 - - - - 0.0000000000004481 74.0
PYH2_k127_308146_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 602.0
PYH2_k127_308146_4 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 512.0
PYH2_k127_308146_5 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 518.0
PYH2_k127_308146_6 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 484.0
PYH2_k127_308146_7 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 454.0
PYH2_k127_308146_8 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 415.0
PYH2_k127_308146_9 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 381.0
PYH2_k127_3085213_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.676e-287 905.0
PYH2_k127_3085213_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.093e-230 740.0
PYH2_k127_3085213_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 394.0
PYH2_k127_3085213_3 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 375.0
PYH2_k127_3085213_4 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 366.0
PYH2_k127_3085213_5 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000003624 133.0
PYH2_k127_3085213_6 Protein of unknown function (DUF952) - - - 0.0000000000000000000421 95.0
PYH2_k127_3089594_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001845 284.0
PYH2_k127_3089594_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000003424 196.0
PYH2_k127_3089594_2 PFAM Bacterial regulatory proteins, gntR family - - - 0.00000000000000000000000000001493 127.0
PYH2_k127_3089594_3 - - - - 0.0000000008023 65.0
PYH2_k127_312309_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1143.0
PYH2_k127_312309_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000002298 243.0
PYH2_k127_313046_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 458.0
PYH2_k127_313046_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 396.0
PYH2_k127_313046_10 Glycine D-amino acid oxidase (deaminating) K00303 - 1.5.3.1 0.000000000000000000000000000004726 125.0
PYH2_k127_313046_11 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000004066 93.0
PYH2_k127_313046_2 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 361.0
PYH2_k127_313046_3 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 346.0
PYH2_k127_313046_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 329.0
PYH2_k127_313046_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000001803 244.0
PYH2_k127_313046_6 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000002207 227.0
PYH2_k127_313046_7 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000001244 164.0
PYH2_k127_313046_8 PFAM extracellular solute-binding protein family 1 K02040 - - 0.000000000000000000000000000000000009614 148.0
PYH2_k127_313046_9 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000005166 130.0
PYH2_k127_3131711_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.151e-319 1001.0
PYH2_k127_3131711_1 Glycoside hydrolase family 44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 568.0
PYH2_k127_3131711_10 regulatory protein GntR HTH - - - 0.000000000000000000000000005713 120.0
PYH2_k127_3131711_11 NUDIX domain - - - 0.000000000000001078 87.0
PYH2_k127_3131711_2 Isocitrate/isopropylmalate dehydrogenase K00052,K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85,1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 512.0
PYH2_k127_3131711_3 PFAM PrpF protein K20451 - 5.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 368.0
PYH2_k127_3131711_4 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 321.0
PYH2_k127_3131711_5 phosphoenolpyruvate K03417,K20454 - 4.1.3.30,4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 294.0
PYH2_k127_3131711_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003972 268.0
PYH2_k127_3131711_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000005113 218.0
PYH2_k127_3131711_8 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003063 201.0
PYH2_k127_3131711_9 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000005315 194.0
PYH2_k127_3145096_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1155.0
PYH2_k127_3145096_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000000000000000004289 141.0
PYH2_k127_3145096_2 transferase activity, transferring glycosyl groups - - - 0.0000000005776 61.0
PYH2_k127_3205544_0 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 584.0
PYH2_k127_3205544_1 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 501.0
PYH2_k127_3205544_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000002512 207.0
PYH2_k127_3205544_12 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000008658 168.0
PYH2_k127_3205544_13 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000001176 166.0
PYH2_k127_3205544_14 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000000000000000000000000000000004358 156.0
PYH2_k127_3205544_15 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000003093 75.0
PYH2_k127_3205544_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 464.0
PYH2_k127_3205544_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 410.0
PYH2_k127_3205544_4 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 367.0
PYH2_k127_3205544_5 PFAM glycosyl transferase group 1 K12995,K13668 - 2.4.1.346,2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 351.0
PYH2_k127_3205544_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 351.0
PYH2_k127_3205544_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 340.0
PYH2_k127_3205544_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 297.0
PYH2_k127_3205544_9 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002109 289.0
PYH2_k127_3209291_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 532.0
PYH2_k127_3209291_1 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000002587 257.0
PYH2_k127_3209291_2 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000002539 160.0
PYH2_k127_3209291_3 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000013 107.0
PYH2_k127_3209291_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000009393 94.0
PYH2_k127_3218223_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.088e-220 695.0
PYH2_k127_3218223_1 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 387.0
PYH2_k127_3218223_2 PFAM VWA containing CoxE family protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 385.0
PYH2_k127_3218223_3 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001909 271.0
PYH2_k127_3218223_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000008789 107.0
PYH2_k127_3218223_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000003687 97.0
PYH2_k127_3218223_6 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000001565 82.0
PYH2_k127_3218223_7 OsmC-like protein - - - 0.00000362 54.0
PYH2_k127_3226536_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 417.0
PYH2_k127_3226536_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002057 282.0
PYH2_k127_3226536_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007654 277.0
PYH2_k127_3226536_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007253 268.0
PYH2_k127_3226536_4 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000000000001792 195.0
PYH2_k127_3226536_5 acetyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000001022 161.0
PYH2_k127_3226536_6 - - - - 0.0000000000000000000001715 100.0
PYH2_k127_3226536_7 AAA ATPase domain - - - 0.0000000000001595 83.0
PYH2_k127_3226536_8 - - - - 0.00001059 53.0
PYH2_k127_3255242_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000007916 219.0
PYH2_k127_3255242_1 Lysophospholipase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.000000000000000000000000000000017 139.0
PYH2_k127_3256551_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000369 214.0
PYH2_k127_3256551_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000005775 191.0
PYH2_k127_3256551_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000007952 177.0
PYH2_k127_3256551_3 CBS domain - - - 0.0000000000000000123 86.0
PYH2_k127_3271692_0 PFAM ABC transporter transmembrane region K06147 - - 1.98e-286 897.0
PYH2_k127_3271692_1 ABC transporter transmembrane region K06147 - - 6.191e-239 752.0
PYH2_k127_3271692_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
PYH2_k127_3271692_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001092 226.0
PYH2_k127_3271692_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000009809 222.0
PYH2_k127_3271692_13 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000005057 204.0
PYH2_k127_3271692_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000001422 186.0
PYH2_k127_3271692_15 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000005994 204.0
PYH2_k127_3271692_16 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000009977 163.0
PYH2_k127_3271692_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000003912 156.0
PYH2_k127_3271692_18 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000002088 156.0
PYH2_k127_3271692_19 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000007975 143.0
PYH2_k127_3271692_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.501e-231 752.0
PYH2_k127_3271692_20 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.00000000000000000000000000000005025 134.0
PYH2_k127_3271692_21 Restriction endonuclease K07448 - - 0.00000000000000000000000000174 113.0
PYH2_k127_3271692_22 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000001171 119.0
PYH2_k127_3271692_23 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000002916 112.0
PYH2_k127_3271692_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000005257 104.0
PYH2_k127_3271692_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000005461 108.0
PYH2_k127_3271692_26 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000001619 99.0
PYH2_k127_3271692_27 Belongs to the Nudix hydrolase family - - - 0.00000000000000001761 89.0
PYH2_k127_3271692_28 Biotin-lipoyl like K01993 - - 0.0000000000000001769 91.0
PYH2_k127_3271692_29 - - - - 0.000000000000007306 78.0
PYH2_k127_3271692_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 570.0
PYH2_k127_3271692_31 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.0000001884 58.0
PYH2_k127_3271692_33 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000645 63.0
PYH2_k127_3271692_34 Transcriptional regulator - - - 0.000002012 57.0
PYH2_k127_3271692_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 509.0
PYH2_k127_3271692_5 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 462.0
PYH2_k127_3271692_6 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 412.0
PYH2_k127_3271692_7 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 384.0
PYH2_k127_3271692_8 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 369.0
PYH2_k127_3271692_9 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 355.0
PYH2_k127_3289757_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 460.0
PYH2_k127_3289757_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003768 248.0
PYH2_k127_3289757_2 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
PYH2_k127_3289757_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000002589 180.0
PYH2_k127_3294433_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
PYH2_k127_3294433_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000006677 183.0
PYH2_k127_3294433_2 Domain of unknown function (DUF4258) - - - 0.00000000000000000000000000000000000000000002516 162.0
PYH2_k127_3294433_3 - - - - 0.000000000000000000000000004863 113.0
PYH2_k127_3378218_0 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 321.0
PYH2_k127_3378218_1 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000339 154.0
PYH2_k127_3390690_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 4.374e-256 797.0
PYH2_k127_3390690_1 penicillin amidase K01434 - 3.5.1.11 2.647e-208 674.0
PYH2_k127_3390690_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 242.0
PYH2_k127_3390690_11 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000003654 198.0
PYH2_k127_3390690_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000004761 189.0
PYH2_k127_3390690_13 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000008798 184.0
PYH2_k127_3390690_14 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001823 169.0
PYH2_k127_3390690_15 - - - - 0.000000000000000000000000000001925 128.0
PYH2_k127_3390690_16 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000001601 100.0
PYH2_k127_3390690_17 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000004563 109.0
PYH2_k127_3390690_18 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000001438 93.0
PYH2_k127_3390690_19 Transcriptional regulator - - - 0.00000000000006008 86.0
PYH2_k127_3390690_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 498.0
PYH2_k127_3390690_20 phospholipase C K01114 - 3.1.4.3 0.0000000000005289 72.0
PYH2_k127_3390690_21 FtsZ-dependent cytokinesis - - - 0.0000000001273 71.0
PYH2_k127_3390690_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 469.0
PYH2_k127_3390690_4 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 458.0
PYH2_k127_3390690_5 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 463.0
PYH2_k127_3390690_6 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K18916 - 1.1.1.26,1.20.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 410.0
PYH2_k127_3390690_7 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 389.0
PYH2_k127_3390690_8 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 313.0
PYH2_k127_3390690_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 309.0
PYH2_k127_3390859_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 353.0
PYH2_k127_3390859_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 311.0
PYH2_k127_3390859_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006588 282.0
PYH2_k127_3390859_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000002256 58.0
PYH2_k127_3399239_0 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 470.0
PYH2_k127_3399239_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 286.0
PYH2_k127_3399239_10 Protein of unknown function (DUF4242) - - - 0.0000000000000000000009772 97.0
PYH2_k127_3399239_11 response to heat K03668 - - 0.00000000000000000009649 95.0
PYH2_k127_3399239_12 DinB family - - - 0.0002741 50.0
PYH2_k127_3399239_2 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000002804 221.0
PYH2_k127_3399239_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000002049 214.0
PYH2_k127_3399239_4 - - - - 0.00000000000000000000000000000000000000000000000000000007887 207.0
PYH2_k127_3399239_5 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000000002706 198.0
PYH2_k127_3399239_6 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000005375 188.0
PYH2_k127_3399239_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000003073 165.0
PYH2_k127_3399239_8 DinB family - - - 0.0000000000000000000000000000000000000197 146.0
PYH2_k127_3399239_9 PFAM LmbE family protein - - - 0.000000000000000000000000000008748 121.0
PYH2_k127_3416580_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 620.0
PYH2_k127_3416580_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000001684 205.0
PYH2_k127_3416580_2 Psort location Cytoplasmic, score 8.87 K00180 - 1.2.7.8 0.00000000000000000000003903 102.0
PYH2_k127_3427648_0 Polysaccharide biosynthesis protein - - - 9.535e-288 930.0
PYH2_k127_3427648_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000001571 141.0
PYH2_k127_3427648_2 Domain of unknown function (DUF1992) - - - 0.000000000000002515 83.0
PYH2_k127_3427648_3 Periplasmic copper-binding protein (NosD) - - - 0.000000001176 70.0
PYH2_k127_3427648_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000003899 57.0
PYH2_k127_35081_0 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001234 259.0
PYH2_k127_35081_1 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000004412 138.0
PYH2_k127_3547124_0 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 446.0
PYH2_k127_3547124_1 COG0044 Dihydroorotase and related cyclic amidohydrolases K01464,K01465 - 3.5.2.2,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 379.0
PYH2_k127_3547124_2 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 359.0
PYH2_k127_3590700_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 5.682e-209 672.0
PYH2_k127_3590700_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 526.0
PYH2_k127_3590700_10 Creatinase/Prolidase N-terminal domain - - - 0.00000000000004738 85.0
PYH2_k127_3590700_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 468.0
PYH2_k127_3590700_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004368 258.0
PYH2_k127_3590700_4 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000001528 230.0
PYH2_k127_3590700_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000001074 213.0
PYH2_k127_3590700_6 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000001209 185.0
PYH2_k127_3590700_7 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000001116 171.0
PYH2_k127_3590700_8 Metallopeptidase family M24 - - - 0.000000000000000000000000003832 119.0
PYH2_k127_3590700_9 Nitroreductase family - - - 0.0000000000000000000000002581 113.0
PYH2_k127_3609207_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 587.0
PYH2_k127_3609207_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 428.0
PYH2_k127_3609207_2 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 323.0
PYH2_k127_3609207_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000415 267.0
PYH2_k127_3609207_4 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000007427 210.0
PYH2_k127_3609207_5 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000002522 210.0
PYH2_k127_3609207_6 Carbon monoxide dehydrogenase subunit G (CoxG) K16877 - 1.3.99.8 0.0000000000000003489 85.0
PYH2_k127_3609207_7 Methyltransferase domain - - - 0.000000001067 67.0
PYH2_k127_3617359_0 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009004 267.0
PYH2_k127_3617359_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002343 264.0
PYH2_k127_3617359_2 DinB family - - - 0.00000000000000000000000000000000000018 143.0
PYH2_k127_3617359_3 YCII-related domain - - - 0.000000000000003308 79.0
PYH2_k127_3617359_4 InterPro IPR014922 - - - 0.0000001036 53.0
PYH2_k127_3623129_0 Uncharacterized conserved protein (DUF2075) - - - 6.763e-297 923.0
PYH2_k127_3623129_1 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 301.0
PYH2_k127_3623129_10 protein secretion K08651 - 3.4.21.66 0.0000000001529 74.0
PYH2_k127_3623129_12 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00003292 49.0
PYH2_k127_3623129_2 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 299.0
PYH2_k127_3623129_3 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000007634 252.0
PYH2_k127_3623129_4 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003789 217.0
PYH2_k127_3623129_5 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000001441 216.0
PYH2_k127_3623129_6 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000002505 138.0
PYH2_k127_3623129_8 Uncharacterised nucleotidyltransferase - - - 0.0000000000001261 83.0
PYH2_k127_3623129_9 protein secretion K08651 - 3.4.21.66 0.000000000004892 79.0
PYH2_k127_3623931_0 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004102 256.0
PYH2_k127_3623931_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000001421 156.0
PYH2_k127_3623931_2 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000002213 133.0
PYH2_k127_3623931_3 Chromate resistance exported protein - - - 0.000000000000000000000000000004381 121.0
PYH2_k127_3627407_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.259e-210 662.0
PYH2_k127_3627407_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 423.0
PYH2_k127_3627407_10 - - - - 0.000000000000000000000002762 108.0
PYH2_k127_3627407_11 Transposase, Mutator family - - - 0.000000000000001731 79.0
PYH2_k127_3627407_12 peptidase - - - 0.000001192 57.0
PYH2_k127_3627407_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 361.0
PYH2_k127_3627407_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001277 269.0
PYH2_k127_3627407_4 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000001184 195.0
PYH2_k127_3627407_5 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000001224 175.0
PYH2_k127_3627407_6 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000001922 173.0
PYH2_k127_3627407_7 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.00000000000000000000000000000000000000001188 163.0
PYH2_k127_3627407_8 Acetyltransferase - - - 0.00000000000000000000000000000000000000008919 159.0
PYH2_k127_3627407_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000373 148.0
PYH2_k127_3673317_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 419.0
PYH2_k127_3673317_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 411.0
PYH2_k127_3673317_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000006391 149.0
PYH2_k127_3673317_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000004352 160.0
PYH2_k127_3673317_12 Putative regulatory protein - - - 0.0000000000000000000000000000000004233 134.0
PYH2_k127_3673317_13 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000000006966 128.0
PYH2_k127_3673317_14 PFAM response regulator receiver K02282 - - 0.000000000000000000000000208 108.0
PYH2_k127_3673317_15 PFAM response regulator receiver K02282 - - 0.00002533 48.0
PYH2_k127_3673317_16 Signal transduction response regulator, receiver region K02488 - 2.7.7.65 0.0009163 43.0
PYH2_k127_3673317_2 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 407.0
PYH2_k127_3673317_3 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
PYH2_k127_3673317_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
PYH2_k127_3673317_5 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000001832 193.0
PYH2_k127_3673317_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000164 190.0
PYH2_k127_3673317_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000116 165.0
PYH2_k127_3673317_8 cellulose binding - - - 0.00000000000000000000000000000000000000000006154 172.0
PYH2_k127_3686054_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.791e-222 696.0
PYH2_k127_3686054_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.107e-210 664.0
PYH2_k127_3686054_10 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000007449 225.0
PYH2_k127_3686054_11 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000002838 231.0
PYH2_k127_3686054_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000001841 221.0
PYH2_k127_3686054_13 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000001738 183.0
PYH2_k127_3686054_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000001222 141.0
PYH2_k127_3686054_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000002054 98.0
PYH2_k127_3686054_16 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000001328 93.0
PYH2_k127_3686054_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000005051 90.0
PYH2_k127_3686054_18 cell adhesion involved in biofilm formation - - - 0.00000000000000001053 87.0
PYH2_k127_3686054_19 - - - - 0.00000000000000003206 83.0
PYH2_k127_3686054_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.131e-206 648.0
PYH2_k127_3686054_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000003665 87.0
PYH2_k127_3686054_21 transcriptional activator domain - - - 0.00000000000000007555 92.0
PYH2_k127_3686054_22 membrane - - - 0.000000000001254 79.0
PYH2_k127_3686054_23 Domain of unknown function (DUF4404) - - - 0.0000000001601 67.0
PYH2_k127_3686054_24 Esterase PHB depolymerase K03932 - - 0.0000000007844 62.0
PYH2_k127_3686054_25 - - - - 0.000001395 51.0
PYH2_k127_3686054_26 - - - - 0.000001887 55.0
PYH2_k127_3686054_27 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000005307 51.0
PYH2_k127_3686054_28 - - - - 0.00002471 48.0
PYH2_k127_3686054_29 Peptidase MA superfamily - - - 0.0001254 53.0
PYH2_k127_3686054_3 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 554.0
PYH2_k127_3686054_30 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.0002065 44.0
PYH2_k127_3686054_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 489.0
PYH2_k127_3686054_5 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
PYH2_k127_3686054_6 NUBPL iron-transfer P-loop NTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 382.0
PYH2_k127_3686054_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005261 264.0
PYH2_k127_3686054_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000282 249.0
PYH2_k127_3686054_9 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
PYH2_k127_3693857_0 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 344.0
PYH2_k127_3693857_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000001843 201.0
PYH2_k127_3732409_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.13e-224 722.0
PYH2_k127_3732409_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 624.0
PYH2_k127_3732409_10 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 392.0
PYH2_k127_3732409_11 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 389.0
PYH2_k127_3732409_12 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 371.0
PYH2_k127_3732409_13 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 320.0
PYH2_k127_3732409_14 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
PYH2_k127_3732409_15 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
PYH2_k127_3732409_16 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005248 244.0
PYH2_k127_3732409_17 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
PYH2_k127_3732409_18 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000003307 236.0
PYH2_k127_3732409_19 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000005561 226.0
PYH2_k127_3732409_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 613.0
PYH2_k127_3732409_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
PYH2_k127_3732409_21 DHH family K00974,K06881 GO:0008150,GO:0040007 2.7.7.72,3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000845 219.0
PYH2_k127_3732409_22 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000000000000000000000000000000000000000000702 171.0
PYH2_k127_3732409_23 Methyltransferase domain - - - 0.000000000000000000000000000000000000001148 157.0
PYH2_k127_3732409_24 domain, Protein - - - 0.00000000000000000000000000000000000001773 159.0
PYH2_k127_3732409_25 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000002351 141.0
PYH2_k127_3732409_26 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000001853 134.0
PYH2_k127_3732409_27 DUF218 domain - - - 0.000000000000000000000000000002058 129.0
PYH2_k127_3732409_28 Protein of unknown function (DUF448) K07742 - - 0.000000000000000001357 88.0
PYH2_k127_3732409_29 helix_turn_helix, Lux Regulon - - - 0.0000000000000001772 88.0
PYH2_k127_3732409_3 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 602.0
PYH2_k127_3732409_30 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000001062 82.0
PYH2_k127_3732409_31 nitrite reductase [NAD(P)H] activity K00363 - 1.7.1.15 0.000000000000005378 86.0
PYH2_k127_3732409_32 Rhodanese Homology Domain - - - 0.00000000000003474 73.0
PYH2_k127_3732409_33 SnoaL-like polyketide cyclase - - - 0.0000000000003319 74.0
PYH2_k127_3732409_34 Protoglobin - - - 0.000000000004389 77.0
PYH2_k127_3732409_36 Protein of unknown function (DUF1059) - - - 0.0000000001049 64.0
PYH2_k127_3732409_37 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000001734 68.0
PYH2_k127_3732409_4 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 532.0
PYH2_k127_3732409_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 494.0
PYH2_k127_3732409_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 455.0
PYH2_k127_3732409_7 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 453.0
PYH2_k127_3732409_8 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 435.0
PYH2_k127_3732409_9 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 419.0
PYH2_k127_37395_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 532.0
PYH2_k127_37395_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 501.0
PYH2_k127_37395_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000003447 100.0
PYH2_k127_37395_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 317.0
PYH2_k127_37395_3 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008812 283.0
PYH2_k127_37395_4 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005795 286.0
PYH2_k127_37395_5 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005314 280.0
PYH2_k127_37395_6 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002126 271.0
PYH2_k127_37395_7 PFAM glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000001066 223.0
PYH2_k127_37395_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000001948 123.0
PYH2_k127_37395_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000233 125.0
PYH2_k127_37548_0 dihydroorotase K01464,K01466 - 3.5.2.2,3.5.2.5 2.687e-234 733.0
PYH2_k127_37548_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 362.0
PYH2_k127_37548_10 racemase - - - 0.0000000000000000001312 97.0
PYH2_k127_37548_11 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000005435 88.0
PYH2_k127_37548_12 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000004942 85.0
PYH2_k127_37548_13 Mg chelatase-like protein K07391 - - 0.0000004119 54.0
PYH2_k127_37548_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 334.0
PYH2_k127_37548_3 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 303.0
PYH2_k127_37548_4 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 281.0
PYH2_k127_37548_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001661 287.0
PYH2_k127_37548_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002348 263.0
PYH2_k127_37548_7 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046,K00059,K07535 - 1.1.1.100,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000006682 212.0
PYH2_k127_37548_8 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000005781 208.0
PYH2_k127_37548_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000002111 130.0
PYH2_k127_3764621_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 4.585e-271 850.0
PYH2_k127_3764621_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.445e-247 789.0
PYH2_k127_3764621_10 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000002872 103.0
PYH2_k127_3764621_11 monooxygenase activity K06966 - 3.2.2.10 0.00000000000001256 75.0
PYH2_k127_3764621_12 WXG100 protein secretion system (Wss), protein YukD - - - 0.000000000009878 69.0
PYH2_k127_3764621_13 VWA domain containing CoxE-like protein K07114 - - 0.0000000007368 71.0
PYH2_k127_3764621_14 iron ion homeostasis K03709,K04758 - - 0.00000001613 60.0
PYH2_k127_3764621_2 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 451.0
PYH2_k127_3764621_3 PFAM UBA THIF-type NAD FAD binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 353.0
PYH2_k127_3764621_4 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007375 242.0
PYH2_k127_3764621_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000396 164.0
PYH2_k127_3764621_6 protein modification by small protein conjugation - - - 0.00000000000000000000000000000000000006402 153.0
PYH2_k127_3764621_7 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000001604 144.0
PYH2_k127_3764621_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000003441 113.0
PYH2_k127_3764621_9 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.000000000000000000000005649 111.0
PYH2_k127_3767653_0 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 327.0
PYH2_k127_3767653_1 Protein of unknown function (DUF664) - - - 0.000000000000000000000757 95.0
PYH2_k127_3767653_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000001469 74.0
PYH2_k127_3783591_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 3.199e-215 685.0
PYH2_k127_3783591_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 9.212e-208 654.0
PYH2_k127_3783591_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0001954 50.0
PYH2_k127_3783591_11 membrane protein domain - - - 0.0008562 43.0
PYH2_k127_3783591_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 408.0
PYH2_k127_3783591_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 346.0
PYH2_k127_3783591_4 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 319.0
PYH2_k127_3783591_5 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003804 273.0
PYH2_k127_3783591_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000002023 199.0
PYH2_k127_3783591_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000007572 200.0
PYH2_k127_3783591_8 - - - - 0.0000000000000000000001128 101.0
PYH2_k127_3783591_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000000008764 70.0
PYH2_k127_3794913_0 Histidine kinase-like ATPases - - - 4.204e-262 873.0
PYH2_k127_3798610_0 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 333.0
PYH2_k127_3798610_1 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 297.0
PYH2_k127_3798610_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000003577 101.0
PYH2_k127_3798610_11 WD40-like Beta Propeller Repeat K03641 - - 0.00000000001982 75.0
PYH2_k127_3798610_12 CopC domain K07156 - - 0.000000003927 68.0
PYH2_k127_3798610_13 TIGRFAM EpsI family protein - - - 0.0002154 52.0
PYH2_k127_3798610_14 SnoaL-like polyketide cyclase K01061,K15945 - 3.1.1.45 0.0005553 49.0
PYH2_k127_3798610_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000799 286.0
PYH2_k127_3798610_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
PYH2_k127_3798610_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000007625 242.0
PYH2_k127_3798610_5 PFAM ATP-binding region ATPase domain protein, histidine kinase A domain protein, histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000422 241.0
PYH2_k127_3798610_6 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000007823 224.0
PYH2_k127_3798610_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000001457 179.0
PYH2_k127_3798610_9 - - - - 0.0000000000000000000000000000000000000003007 156.0
PYH2_k127_3807318_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 505.0
PYH2_k127_3807318_1 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000002267 152.0
PYH2_k127_3817321_0 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 357.0
PYH2_k127_3817321_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000195 78.0
PYH2_k127_3817321_2 - - - - 0.00007931 56.0
PYH2_k127_3817321_3 S-layer homology domain - - - 0.0001818 55.0
PYH2_k127_3824337_0 Peptidoglycan-binding lysin domain - - - 0.00000000000000000006279 102.0
PYH2_k127_3824337_1 Lamin Tail Domain - - - 0.000000008524 67.0
PYH2_k127_3824337_2 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000162 57.0
PYH2_k127_3825601_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 432.0
PYH2_k127_3825601_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008997 271.0
PYH2_k127_3825601_2 PaaX family transcrtiptional regulator K02616 - - 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
PYH2_k127_3825601_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000001897 228.0
PYH2_k127_3825601_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000001241 208.0
PYH2_k127_3825601_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000001689 180.0
PYH2_k127_3825601_6 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000005356 171.0
PYH2_k127_3830847_0 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 331.0
PYH2_k127_3830847_1 Metallo-beta-lactamase superfamily - - - 0.00000000002358 67.0
PYH2_k127_3837687_0 Oligopeptidase F - - - 4.459e-207 657.0
PYH2_k127_3837687_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 516.0
PYH2_k127_3838281_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.8e-289 900.0
PYH2_k127_3838281_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 384.0
PYH2_k127_3838281_10 - - - - 0.000000000000000000000000005049 115.0
PYH2_k127_3838281_11 - - - - 0.000000000000002985 85.0
PYH2_k127_3838281_12 Cupin domain - - - 0.00000000002648 70.0
PYH2_k127_3838281_13 PFAM Integrase - - - 0.000008518 51.0
PYH2_k127_3838281_2 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 369.0
PYH2_k127_3838281_3 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000162 272.0
PYH2_k127_3838281_4 metal-dependent membrane protease K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002612 265.0
PYH2_k127_3838281_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007407 255.0
PYH2_k127_3838281_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004092 221.0
PYH2_k127_3838281_7 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001033 196.0
PYH2_k127_3838281_8 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000002044 151.0
PYH2_k127_3838281_9 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000000000004175 133.0
PYH2_k127_3896537_0 Universal stress protein - - - 0.00000000000000000000000000000000000000000000006084 181.0
PYH2_k127_3896537_1 GAF domain - - - 0.00000000000000000000000000006855 123.0
PYH2_k127_3896537_2 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688,K18675 - 2.4.1.20,2.4.1.280 0.0000000000000000000000000004696 119.0
PYH2_k127_3896537_3 Transglycosylase associated protein - - - 0.000000000000001973 79.0
PYH2_k127_3896537_4 Belongs to the UPF0337 (CsbD) family - - - 0.0000000001697 65.0
PYH2_k127_3896537_5 DnaJ molecular chaperone homology domain - - - 0.00000003652 55.0
PYH2_k127_3897879_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 454.0
PYH2_k127_3897879_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 448.0
PYH2_k127_3897879_10 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000002003 88.0
PYH2_k127_3897879_11 Domain of unknown function (DUF1932) - - - 0.000000002929 60.0
PYH2_k127_3897879_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 428.0
PYH2_k127_3897879_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 395.0
PYH2_k127_3897879_4 nitrogen compound transport K00759,K02033 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 380.0
PYH2_k127_3897879_5 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 325.0
PYH2_k127_3897879_6 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000458 194.0
PYH2_k127_3897879_7 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000000002257 135.0
PYH2_k127_3897879_8 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000003742 143.0
PYH2_k127_3897879_9 Cupin domain - - - 0.0000000000000000000000000000006979 124.0
PYH2_k127_391877_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.754e-235 768.0
PYH2_k127_391877_1 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 529.0
PYH2_k127_391877_10 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000000000003063 190.0
PYH2_k127_391877_11 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000003896 137.0
PYH2_k127_391877_12 - - - - 0.000000000000000000000000001015 122.0
PYH2_k127_391877_13 Esterase PHB depolymerase - - - 0.000000000000000000007122 94.0
PYH2_k127_391877_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000005929 93.0
PYH2_k127_391877_15 WD40 domain protein beta Propeller K03641 - - 0.00000000000005177 84.0
PYH2_k127_391877_16 - - - - 0.0000000000003067 76.0
PYH2_k127_391877_17 gas vesicle protein - - - 0.0000000000004009 74.0
PYH2_k127_391877_18 - - - - 0.0000000000004962 72.0
PYH2_k127_391877_19 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000235 69.0
PYH2_k127_391877_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 425.0
PYH2_k127_391877_20 Fic/DOC family K07341 - - 0.0003276 44.0
PYH2_k127_391877_21 TIGRFAM RHS repeat-associated core domain - - - 0.0005763 44.0
PYH2_k127_391877_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 372.0
PYH2_k127_391877_4 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
PYH2_k127_391877_5 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000576 275.0
PYH2_k127_391877_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
PYH2_k127_391877_7 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004998 271.0
PYH2_k127_391877_8 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000006686 228.0
PYH2_k127_391877_9 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000001233 228.0
PYH2_k127_3941642_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 6.226e-274 857.0
PYH2_k127_3941642_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 8.251e-237 751.0
PYH2_k127_3941642_10 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001003 139.0
PYH2_k127_3941642_11 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000228 138.0
PYH2_k127_3941642_12 Serine aminopeptidase, S33 - - - 0.000000000000002557 76.0
PYH2_k127_3941642_13 - - - - 0.00000000000009793 76.0
PYH2_k127_3941642_14 thiolester hydrolase activity - - - 0.0007178 45.0
PYH2_k127_3941642_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 576.0
PYH2_k127_3941642_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 396.0
PYH2_k127_3941642_4 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 322.0
PYH2_k127_3941642_5 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003792 282.0
PYH2_k127_3941642_6 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000000000000000001711 231.0
PYH2_k127_3941642_7 Domain of unknown function - - - 0.0000000000000000000000000000000000000000000000004265 184.0
PYH2_k127_3941642_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000003273 177.0
PYH2_k127_3941642_9 TIGRFAM phosphoesterase, MJ0936 family - - - 0.00000000000000000000000000000000000000871 153.0
PYH2_k127_394193_0 NMT1-like family - - - 0.000000000000000000000006915 113.0
PYH2_k127_394193_1 Protein of unknown function (DUF1059) - - - 0.0000000001744 63.0
PYH2_k127_3971196_0 Sigma factor PP2C-like phosphatases K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000004761 238.0
PYH2_k127_3971196_1 - - - - 0.0000000000000000000000000000000000000000000000006409 183.0
PYH2_k127_3971196_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000005214 181.0
PYH2_k127_3971196_3 STAS domain K04749,K06378 - - 0.0000008623 56.0
PYH2_k127_3971251_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000009663 123.0
PYH2_k127_3971251_1 Methyltransferase domain - - - 0.000000000000000000000001618 112.0
PYH2_k127_3993408_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 537.0
PYH2_k127_3993408_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002899 263.0
PYH2_k127_3993408_2 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002913 256.0
PYH2_k127_3993408_3 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002236 268.0
PYH2_k127_3993408_4 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000392 228.0
PYH2_k127_3993408_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000003864 229.0
PYH2_k127_3993408_6 Nacht domain - - - 0.000002023 61.0
PYH2_k127_3993408_7 - - - - 0.0001843 52.0
PYH2_k127_3993408_8 - - - - 0.000393 48.0
PYH2_k127_4009033_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.972e-258 808.0
PYH2_k127_4009033_1 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 488.0
PYH2_k127_4009033_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 446.0
PYH2_k127_4009033_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 406.0
PYH2_k127_4009033_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000005975 261.0
PYH2_k127_4009033_5 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000003746 182.0
PYH2_k127_4009033_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000003709 128.0
PYH2_k127_4009033_7 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000001949 100.0
PYH2_k127_4009033_8 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000001005 66.0
PYH2_k127_4041866_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
PYH2_k127_4041866_1 transcriptional regulator, SARP family - - - 0.0006157 48.0
PYH2_k127_4047216_0 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007958 273.0
PYH2_k127_4047216_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001287 210.0
PYH2_k127_4047216_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000004989 182.0
PYH2_k127_4047216_3 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000001644 160.0
PYH2_k127_4047216_4 - - - - 0.000000000000000001033 96.0
PYH2_k127_4047216_5 - - - - 0.00007543 51.0
PYH2_k127_4066132_0 AAA domain K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000007733 166.0
PYH2_k127_4066132_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000002715 109.0
PYH2_k127_4066132_2 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000003123 94.0
PYH2_k127_4066132_3 - - - - 0.000000002289 66.0
PYH2_k127_4086531_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006662 264.0
PYH2_k127_4086531_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000212 218.0
PYH2_k127_4086531_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000273 208.0
PYH2_k127_4086531_3 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000005655 169.0
PYH2_k127_4086531_4 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000008205 171.0
PYH2_k127_4086531_5 Methionine biosynthesis protein MetW K20444 - - 0.000000000000000000000000000000003154 138.0
PYH2_k127_413370_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 447.0
PYH2_k127_413370_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000003777 225.0
PYH2_k127_4140337_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 321.0
PYH2_k127_4140337_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 316.0
PYH2_k127_4140337_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000005145 166.0
PYH2_k127_4148122_0 Glycosyltransferase 36 associated - - - 1.426e-309 969.0
PYH2_k127_4148122_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 552.0
PYH2_k127_4148122_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 366.0
PYH2_k127_4148122_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000001773 75.0
PYH2_k127_417414_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 408.0
PYH2_k127_417414_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002286 286.0
PYH2_k127_417414_2 amidohydrolase K21613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003757 278.0
PYH2_k127_4190526_0 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000235 225.0
PYH2_k127_4190526_1 - - - - 0.0000000000000000000000002274 109.0
PYH2_k127_4190526_2 Integrase core domain - - - 0.000000001353 59.0
PYH2_k127_4197157_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 4.218e-238 743.0
PYH2_k127_4197157_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 586.0
PYH2_k127_4197157_10 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 361.0
PYH2_k127_4197157_11 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 356.0
PYH2_k127_4197157_12 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
PYH2_k127_4197157_13 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
PYH2_k127_4197157_14 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001848 267.0
PYH2_k127_4197157_15 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001849 284.0
PYH2_k127_4197157_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000004612 246.0
PYH2_k127_4197157_17 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000001781 230.0
PYH2_k127_4197157_18 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000006442 231.0
PYH2_k127_4197157_19 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000005985 213.0
PYH2_k127_4197157_2 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 553.0
PYH2_k127_4197157_20 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
PYH2_k127_4197157_21 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000024 214.0
PYH2_k127_4197157_22 polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000003047 182.0
PYH2_k127_4197157_23 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000943 181.0
PYH2_k127_4197157_24 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000001919 177.0
PYH2_k127_4197157_25 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000002723 160.0
PYH2_k127_4197157_26 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000001413 150.0
PYH2_k127_4197157_27 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000003209 146.0
PYH2_k127_4197157_28 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000002822 134.0
PYH2_k127_4197157_29 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000111 134.0
PYH2_k127_4197157_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 541.0
PYH2_k127_4197157_30 Thioesterase superfamily K02614 - - 0.000000000000000000000000000003886 125.0
PYH2_k127_4197157_31 PFAM ThiS family K03636 - - 0.0000000000000000000000000005056 115.0
PYH2_k127_4197157_32 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.000000000000000000000003589 104.0
PYH2_k127_4197157_33 methyltransferase - - - 0.0000000000000000000001121 98.0
PYH2_k127_4197157_34 Sulfurtransferase TusA K00392,K04085 - 1.8.7.1 0.000000000000000000005437 95.0
PYH2_k127_4197157_35 Domain of unknown function (DUF4349) - - - 0.000000000000000000033 102.0
PYH2_k127_4197157_36 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000005189 91.0
PYH2_k127_4197157_37 Pfam:DUF59 - - - 0.0000000000000000383 85.0
PYH2_k127_4197157_38 topology modulation protein - - - 0.0000000114 56.0
PYH2_k127_4197157_39 methyltransferase - - - 0.00000001863 59.0
PYH2_k127_4197157_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 504.0
PYH2_k127_4197157_40 methyltransferase - - - 0.00000002817 55.0
PYH2_k127_4197157_41 COG0563 Adenylate kinase and related kinases - - - 0.0000006805 52.0
PYH2_k127_4197157_42 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000006833 60.0
PYH2_k127_4197157_43 COG0563 Adenylate kinase and related kinases - - - 0.000002321 50.0
PYH2_k127_4197157_44 Tetratricopeptide repeat - - - 0.0002234 50.0
PYH2_k127_4197157_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 466.0
PYH2_k127_4197157_6 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 466.0
PYH2_k127_4197157_7 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 406.0
PYH2_k127_4197157_8 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 389.0
PYH2_k127_4197157_9 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 380.0
PYH2_k127_4205305_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 439.0
PYH2_k127_4205305_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 356.0
PYH2_k127_4205305_10 Oxidoreductase K17218 - 1.8.5.4 0.000000001409 60.0
PYH2_k127_4205305_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006683 258.0
PYH2_k127_4205305_3 PaaX-like protein K02616 - - 0.000000000000000000000000000000000000000000000000000000000000000000003671 244.0
PYH2_k127_4205305_4 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000004408 222.0
PYH2_k127_4205305_5 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000001482 220.0
PYH2_k127_4205305_6 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000002976 172.0
PYH2_k127_4205305_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000001385 103.0
PYH2_k127_4205305_8 Glycosyl hydrolase catalytic core - - - 0.000000000000000000001903 105.0
PYH2_k127_4205305_9 YwiC-like protein - - - 0.0000000005193 70.0
PYH2_k127_4234112_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1265.0
PYH2_k127_4234112_1 Tetratricopeptide TPR_2 repeat protein - - - 4.341e-268 881.0
PYH2_k127_4234112_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 409.0
PYH2_k127_4234112_11 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 348.0
PYH2_k127_4234112_12 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 347.0
PYH2_k127_4234112_13 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 347.0
PYH2_k127_4234112_14 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 282.0
PYH2_k127_4234112_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000005939 209.0
PYH2_k127_4234112_16 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000008722 164.0
PYH2_k127_4234112_17 LysE type translocator - - - 0.00000000000000000000000000000000000001294 152.0
PYH2_k127_4234112_18 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000001893 134.0
PYH2_k127_4234112_19 Protein conserved in bacteria - - - 0.0000000000000000000000000000002845 132.0
PYH2_k127_4234112_2 PFAM NHL repeat containing protein - - - 8.556e-197 654.0
PYH2_k127_4234112_20 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000006903 83.0
PYH2_k127_4234112_22 NUDIX domain - - - 0.000000000000001503 83.0
PYH2_k127_4234112_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000002661 80.0
PYH2_k127_4234112_24 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000006163 71.0
PYH2_k127_4234112_25 Periplasmic copper-binding protein (NosD) - - - 0.00006191 55.0
PYH2_k127_4234112_3 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 499.0
PYH2_k127_4234112_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 477.0
PYH2_k127_4234112_5 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 467.0
PYH2_k127_4234112_6 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 425.0
PYH2_k127_4234112_7 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 443.0
PYH2_k127_4234112_8 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 421.0
PYH2_k127_4234112_9 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 416.0
PYH2_k127_4280195_0 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000561 139.0
PYH2_k127_4280195_1 response regulator - - - 0.000000000000000004608 87.0
PYH2_k127_4280195_2 Protein of unknown function (DUF4242) - - - 0.00000000005405 67.0
PYH2_k127_4285577_0 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000005158 256.0
PYH2_k127_4285577_1 protein kinase activity - - - 0.0001093 55.0
PYH2_k127_431862_0 TIGRFAM Translation elongation factor K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 518.0
PYH2_k127_431862_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 491.0
PYH2_k127_431862_2 sequence-specific DNA binding - - - 0.0000000000000009837 85.0
PYH2_k127_431862_3 Tetratricopeptide repeat - - - 0.000006622 55.0
PYH2_k127_4318887_0 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 445.0
PYH2_k127_4318887_1 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 326.0
PYH2_k127_4318887_10 diguanylate cyclase - - - 0.000000001872 70.0
PYH2_k127_4318887_11 Tetratricopeptide repeat - - - 0.00000001771 66.0
PYH2_k127_4318887_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004525 281.0
PYH2_k127_4318887_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000003197 194.0
PYH2_k127_4318887_4 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000004295 185.0
PYH2_k127_4318887_5 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000006365 180.0
PYH2_k127_4318887_6 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000006094 130.0
PYH2_k127_4318887_7 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000011 114.0
PYH2_k127_4318887_8 - - - - 0.0000000000000427 74.0
PYH2_k127_4318887_9 Sigma-54 interaction domain protein K07713 - - 0.000000000009094 78.0
PYH2_k127_4327299_0 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 492.0
PYH2_k127_4327299_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 372.0
PYH2_k127_4327299_10 Protein conserved in bacteria - - - 0.0000000000000000000000000004007 119.0
PYH2_k127_4327299_11 YGGT family K02221 - - 0.00000000000002644 76.0
PYH2_k127_4327299_12 Ribosomal L28 family K02902 - - 0.0000000002122 66.0
PYH2_k127_4327299_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009608 280.0
PYH2_k127_4327299_3 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006965 263.0
PYH2_k127_4327299_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07640,K07643,K07645,K07649,K19609 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000149 250.0
PYH2_k127_4327299_5 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000002182 236.0
PYH2_k127_4327299_6 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
PYH2_k127_4327299_7 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000001443 223.0
PYH2_k127_4327299_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000006157 216.0
PYH2_k127_4327299_9 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000838 203.0
PYH2_k127_4368376_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 580.0
PYH2_k127_4368376_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 476.0
PYH2_k127_4368376_2 Belongs to the ABC transporter superfamily K02031,K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 464.0
PYH2_k127_4368376_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 417.0
PYH2_k127_4368376_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 400.0
PYH2_k127_4368376_5 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005341 264.0
PYH2_k127_4368376_6 Cyclic-di-AMP receptor - - - 0.0000000000007448 77.0
PYH2_k127_4368376_7 Cyclic-di-AMP receptor - - - 0.000000000001859 76.0
PYH2_k127_4368376_8 Integrase core domain - - - 0.0002405 44.0
PYH2_k127_4370418_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005707 277.0
PYH2_k127_4370418_1 - - - - 0.00000000000000000000000000003024 126.0
PYH2_k127_4370418_2 Contains PIN domain - - - 0.000000000000000000007456 93.0
PYH2_k127_4370418_3 - K07066 - - 0.0000000011 59.0
PYH2_k127_4390336_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000002347 214.0
PYH2_k127_4390336_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000001718 85.0
PYH2_k127_4390336_3 Peptidase family C25 - - - 0.0000000004357 70.0
PYH2_k127_4390336_4 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000001361 64.0
PYH2_k127_4390336_6 Belongs to the peptidase S8 family K01361,K08652,K14647 - 3.4.21.110,3.4.21.96 0.0000001782 63.0
PYH2_k127_4390336_7 Pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.00007302 46.0
PYH2_k127_4395514_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 480.0
PYH2_k127_4395514_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 468.0
PYH2_k127_4395514_10 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000002522 126.0
PYH2_k127_4395514_11 Protein of unknown function (DUF2905) - - - 0.00000000000001914 76.0
PYH2_k127_4395514_12 Cytochrome c - - - 0.00000000001237 79.0
PYH2_k127_4395514_13 PFAM copper resistance protein CopC K14166 - - 0.0000000002304 68.0
PYH2_k127_4395514_14 - - - - 0.000000015 60.0
PYH2_k127_4395514_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 462.0
PYH2_k127_4395514_3 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002321 278.0
PYH2_k127_4395514_4 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001167 271.0
PYH2_k127_4395514_5 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000003388 245.0
PYH2_k127_4395514_6 Copper resistance protein CopC K14166 - - 0.000000000000000000000000000000000000000000000000000000000000005632 246.0
PYH2_k127_4395514_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000006576 219.0
PYH2_k127_4395514_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000008028 195.0
PYH2_k127_4395514_9 - - - - 0.0000000000000000000000000000000002458 134.0
PYH2_k127_4419671_0 calcium- and calmodulin-responsive adenylate cyclase activity K01269,K01406 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 370.0
PYH2_k127_4419671_1 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 302.0
PYH2_k127_4419671_2 - - - - 0.000000000000000000000000000000000000000000000001399 178.0
PYH2_k127_4419671_3 cellular response to heat K09807 - - 0.0000000000000000000000000000000000004862 150.0
PYH2_k127_4419671_4 Dual specificity phosphatase, catalytic domain K14819 GO:0000003,GO:0000027,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0008138,GO:0008150,GO:0008152,GO:0009272,GO:0009653,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010494,GO:0010506,GO:0010508,GO:0010638,GO:0010927,GO:0016043,GO:0016239,GO:0016241,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030154,GO:0030435,GO:0030437,GO:0030476,GO:0030684,GO:0030687,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0032991,GO:0033043,GO:0034293,GO:0034622,GO:0035335,GO:0035556,GO:0035770,GO:0036211,GO:0036464,GO:0042244,GO:0042254,GO:0042255,GO:0042273,GO:0042546,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0043935,GO:0044085,GO:0044087,GO:0044088,GO:0044089,GO:0044090,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045229,GO:0048468,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051321,GO:0051704,GO:0051716,GO:0065003,GO:0065007,GO:0070590,GO:0070591,GO:0070726,GO:0070925,GO:0071554,GO:0071555,GO:0071704,GO:0071826,GO:0071840,GO:0071852,GO:0071940,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1903046,GO:1990904,GO:2000785,GO:2000786 3.1.3.16,3.1.3.48 0.000000803 60.0
PYH2_k127_4419671_5 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00001369 49.0
PYH2_k127_4459541_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 552.0
PYH2_k127_4459541_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 362.0
PYH2_k127_4459541_2 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001251 246.0
PYH2_k127_4459541_3 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000007927 243.0
PYH2_k127_4459541_4 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001405 244.0
PYH2_k127_4459541_5 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000223 240.0
PYH2_k127_4459541_6 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000002232 211.0
PYH2_k127_4459541_7 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000002151 206.0
PYH2_k127_4459541_8 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000491 79.0
PYH2_k127_4477962_0 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 419.0
PYH2_k127_4477962_1 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000059 288.0
PYH2_k127_4477962_2 - - - - 0.0000000000003293 79.0
PYH2_k127_4507507_0 VWA domain containing CoxE-like protein K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 595.0
PYH2_k127_4507507_1 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 487.0
PYH2_k127_4507507_10 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 334.0
PYH2_k127_4507507_11 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 325.0
PYH2_k127_4507507_12 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 314.0
PYH2_k127_4507507_13 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
PYH2_k127_4507507_14 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
PYH2_k127_4507507_15 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009662 287.0
PYH2_k127_4507507_16 Cytochrome C and Quinol oxidase polypeptide I K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005887 266.0
PYH2_k127_4507507_17 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000001849 250.0
PYH2_k127_4507507_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.00000000000000000000000000000000000000000000000000000000000000002948 234.0
PYH2_k127_4507507_19 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001403 224.0
PYH2_k127_4507507_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 465.0
PYH2_k127_4507507_20 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000007722 214.0
PYH2_k127_4507507_21 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000003542 188.0
PYH2_k127_4507507_22 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000002434 183.0
PYH2_k127_4507507_23 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000003715 160.0
PYH2_k127_4507507_24 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000002779 147.0
PYH2_k127_4507507_25 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000006323 143.0
PYH2_k127_4507507_26 Thioredoxin - - - 0.0000000000000000000000000000000323 130.0
PYH2_k127_4507507_27 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000001525 110.0
PYH2_k127_4507507_28 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000002689 99.0
PYH2_k127_4507507_29 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000001785 68.0
PYH2_k127_4507507_3 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 441.0
PYH2_k127_4507507_30 Subtilase family - - - 0.000000003202 60.0
PYH2_k127_4507507_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 425.0
PYH2_k127_4507507_5 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 433.0
PYH2_k127_4507507_6 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 409.0
PYH2_k127_4507507_7 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 381.0
PYH2_k127_4507507_8 Membrane dipeptidase (Peptidase family M19) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 366.0
PYH2_k127_4507507_9 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 364.0
PYH2_k127_4550397_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1102.0
PYH2_k127_4550397_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 290.0
PYH2_k127_4550397_2 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000001365 246.0
PYH2_k127_4550397_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000003029 169.0
PYH2_k127_4550397_4 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000002333 140.0
PYH2_k127_4550397_5 PFAM WD40 domain protein beta Propeller - - - 0.0000000006067 65.0
PYH2_k127_4550397_6 - - - - 0.00001218 54.0
PYH2_k127_4550397_7 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0004873 52.0
PYH2_k127_455299_0 PFAM Translin K07477 - - 0.000002895 52.0
PYH2_k127_455299_1 metallopeptidase activity - - - 0.00003309 55.0
PYH2_k127_455299_2 Belongs to the peptidase C1 family - - - 0.00009699 54.0
PYH2_k127_4571170_0 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 331.0
PYH2_k127_4571170_1 ABC transporter (Permease) K02042 - - 0.000000000000000000000000000000000000000000002469 177.0
PYH2_k127_4571170_2 Phosphonate ABC transporter K02044 - - 0.00000000000000000000000000001377 132.0
PYH2_k127_457311_0 SPTR Transposase IS4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 384.0
PYH2_k127_457311_1 Helix-turn-helix of DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000001438 153.0
PYH2_k127_457311_2 DDE superfamily endonuclease - - - 0.000000000001875 70.0
PYH2_k127_457359_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 359.0
PYH2_k127_4589429_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 1.651e-243 784.0
PYH2_k127_4589429_1 PFAM amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 570.0
PYH2_k127_4589429_10 COG2346, Truncated hemoglobins - - - 0.0000000000001692 72.0
PYH2_k127_4589429_2 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 507.0
PYH2_k127_4589429_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 359.0
PYH2_k127_4589429_4 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 302.0
PYH2_k127_4589429_5 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006828 271.0
PYH2_k127_4589429_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
PYH2_k127_4589429_7 diguanylate cyclase K21020 - 2.7.7.65 0.0000000000000000000000000000000007713 142.0
PYH2_k127_4589429_8 Protein of unknown function (DUF664) - - - 0.0000000000000000106 90.0
PYH2_k127_4589429_9 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000002238 93.0
PYH2_k127_4614709_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.836e-215 681.0
PYH2_k127_4614709_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 546.0
PYH2_k127_4614709_10 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000001334 136.0
PYH2_k127_4614709_11 flavoprotein involved in K transport - - - 0.000000002738 68.0
PYH2_k127_4614709_12 Adenylate cyclase K01768 - 4.6.1.1 0.000000003827 59.0
PYH2_k127_4614709_2 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 535.0
PYH2_k127_4614709_3 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 383.0
PYH2_k127_4614709_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 305.0
PYH2_k127_4614709_5 Succinyl-CoA ligase like flavodoxin domain - - - 0.000000000000000000000000000000000000000000000000000000005408 208.0
PYH2_k127_4614709_6 dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000002179 192.0
PYH2_k127_4614709_7 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000001244 178.0
PYH2_k127_4614709_8 - - - - 0.000000000000000000000000000000000000000002381 158.0
PYH2_k127_4614709_9 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000009629 164.0
PYH2_k127_4629693_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
PYH2_k127_4629693_1 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000007185 224.0
PYH2_k127_4629693_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000002459 185.0
PYH2_k127_4629693_3 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000004908 107.0
PYH2_k127_4629693_4 F420H(2)-dependent quinone reductase - - - 0.000000000001788 74.0
PYH2_k127_4629693_5 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000114 57.0
PYH2_k127_4654708_0 ABC transporter substrate-binding protein K17318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 570.0
PYH2_k127_4654708_1 ABC transporter substrate-binding protein K17318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 549.0
PYH2_k127_4654708_10 Fumarylacetoacetate (FAA) hydrolase family K16164 - 3.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 310.0
PYH2_k127_4654708_11 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 321.0
PYH2_k127_4654708_12 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000003717 262.0
PYH2_k127_4654708_13 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000227 237.0
PYH2_k127_4654708_14 Carboxylesterase family - - - 0.00000000000000000000000000000000000001129 154.0
PYH2_k127_4654708_15 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000007525 144.0
PYH2_k127_4654708_16 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000002282 130.0
PYH2_k127_4654708_17 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000002641 103.0
PYH2_k127_4654708_18 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000003747 77.0
PYH2_k127_4654708_19 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000001151 68.0
PYH2_k127_4654708_2 Glycosyl hydrolases family 2, TIM barrel domain K01195 - 3.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 532.0
PYH2_k127_4654708_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
PYH2_k127_4654708_4 COG NOG07603 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 457.0
PYH2_k127_4654708_5 Sugar ABC transporter permease K17319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 426.0
PYH2_k127_4654708_6 Sugar ABC transporter permease K17320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
PYH2_k127_4654708_7 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 340.0
PYH2_k127_4654708_8 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 342.0
PYH2_k127_4654708_9 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 319.0
PYH2_k127_4694639_0 DEAD DEAH box helicase domain protein K06877 - - 9.96e-295 925.0
PYH2_k127_4694639_1 DNA polymerase K02337,K14162 - 2.7.7.7 1.554e-198 655.0
PYH2_k127_4694639_10 Protease prsW family - - - 0.000005695 58.0
PYH2_k127_4694639_11 Transcriptional regulatory protein, C terminal K07667 - - 0.00007521 51.0
PYH2_k127_4694639_2 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 416.0
PYH2_k127_4694639_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000751 270.0
PYH2_k127_4694639_4 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001016 261.0
PYH2_k127_4694639_5 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000002244 233.0
PYH2_k127_4694639_6 PFAM Signal transduction response regulator, receiver K07660,K07667 - - 0.000000000000000000000000000000000000000000000000000001701 198.0
PYH2_k127_4694639_7 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components K05785 - - 0.0000000000000009585 85.0
PYH2_k127_4694639_8 PFAM Protein kinase domain - - - 0.00000000461 63.0
PYH2_k127_4718933_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1082.0
PYH2_k127_4718933_1 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 424.0
PYH2_k127_4718933_10 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000004254 67.0
PYH2_k127_4718933_11 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000003937 61.0
PYH2_k127_4718933_2 Peptidase, M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 415.0
PYH2_k127_4718933_3 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000006868 188.0
PYH2_k127_4718933_4 domain protein - - - 0.0000000000000000000000000000000000000000003844 166.0
PYH2_k127_4718933_5 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000009552 156.0
PYH2_k127_4718933_6 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000006018 115.0
PYH2_k127_4718933_7 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000006285 93.0
PYH2_k127_4718933_8 Domain of unknown function (DUF1330) - - - 0.00000000000000000008151 90.0
PYH2_k127_4718933_9 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000008377 83.0
PYH2_k127_4723818_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 378.0
PYH2_k127_4723818_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 335.0
PYH2_k127_4730506_0 PFAM Prolyl oligopeptidase family - - - 6.817e-263 827.0
PYH2_k127_4730506_1 elongation factor Tu domain 2 protein K06207 - - 1.197e-256 806.0
PYH2_k127_4730506_10 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
PYH2_k127_4730506_11 Binding-protein-dependent transport system inner membrane component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002825 279.0
PYH2_k127_4730506_12 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006868 268.0
PYH2_k127_4730506_13 ABC-type sugar transport systems, permease components K02025,K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
PYH2_k127_4730506_14 protein (ATP-grasp superfamily) K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001395 255.0
PYH2_k127_4730506_15 arginine transmembrane transporter activity K06895 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - 0.0000000000000000000000000000000000000000000000000000000000000002964 227.0
PYH2_k127_4730506_16 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000003018 209.0
PYH2_k127_4730506_17 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000007755 208.0
PYH2_k127_4730506_18 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000001145 183.0
PYH2_k127_4730506_19 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000006134 173.0
PYH2_k127_4730506_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.253e-199 635.0
PYH2_k127_4730506_20 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000001876 160.0
PYH2_k127_4730506_21 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000004723 129.0
PYH2_k127_4730506_22 Pep-cterm family integral membrane protein - - - 0.0000000000000000000004509 102.0
PYH2_k127_4730506_23 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000001459 74.0
PYH2_k127_4730506_24 Transcriptional regulator - - - 0.000000001409 60.0
PYH2_k127_4730506_25 HEAT repeats - - - 0.00000003027 64.0
PYH2_k127_4730506_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000004576 63.0
PYH2_k127_4730506_27 - - - - 0.000001784 56.0
PYH2_k127_4730506_3 Pfam:DUF162 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 601.0
PYH2_k127_4730506_4 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 526.0
PYH2_k127_4730506_5 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 440.0
PYH2_k127_4730506_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 428.0
PYH2_k127_4730506_7 ABC-type sugar transport system, periplasmic component K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 415.0
PYH2_k127_4730506_8 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 363.0
PYH2_k127_4730506_9 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 325.0
PYH2_k127_4732034_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 548.0
PYH2_k127_4732034_1 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 375.0
PYH2_k127_4732034_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000001267 93.0
PYH2_k127_4732034_3 Domain of unknown function (DUF4926) - - - 0.000000000000000009884 83.0
PYH2_k127_4742456_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 6.322e-215 682.0
PYH2_k127_4742456_1 proline dipeptidase activity - - - 4.04e-212 668.0
PYH2_k127_4742456_10 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000006822 224.0
PYH2_k127_4742456_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000001153 184.0
PYH2_k127_4742456_12 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000001516 168.0
PYH2_k127_4742456_13 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000006386 166.0
PYH2_k127_4742456_14 Lipocalin-like domain - - - 0.000000000000000000000000000000002284 133.0
PYH2_k127_4742456_15 Phage integrase family K03733 - - 0.000000000000000000000007284 111.0
PYH2_k127_4742456_16 Thioesterase superfamily K07107 - - 0.000000000000000000003711 98.0
PYH2_k127_4742456_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 510.0
PYH2_k127_4742456_3 PFAM dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 466.0
PYH2_k127_4742456_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 380.0
PYH2_k127_4742456_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 385.0
PYH2_k127_4742456_6 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
PYH2_k127_4742456_7 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 348.0
PYH2_k127_4742456_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
PYH2_k127_4742456_9 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
PYH2_k127_4765328_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1742.0
PYH2_k127_4765328_1 CoA binding domain K09181 - - 2.169e-311 981.0
PYH2_k127_4765328_10 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 349.0
PYH2_k127_4765328_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 327.0
PYH2_k127_4765328_12 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 320.0
PYH2_k127_4765328_13 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 312.0
PYH2_k127_4765328_14 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 304.0
PYH2_k127_4765328_15 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 297.0
PYH2_k127_4765328_16 Two component transcriptional regulator, winged helix family K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
PYH2_k127_4765328_17 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004625 243.0
PYH2_k127_4765328_18 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000003473 234.0
PYH2_k127_4765328_19 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000573 225.0
PYH2_k127_4765328_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 559.0
PYH2_k127_4765328_20 depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000003628 223.0
PYH2_k127_4765328_21 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000002788 196.0
PYH2_k127_4765328_22 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000149 197.0
PYH2_k127_4765328_23 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000107 192.0
PYH2_k127_4765328_24 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000004023 192.0
PYH2_k127_4765328_25 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000001145 190.0
PYH2_k127_4765328_26 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000007998 158.0
PYH2_k127_4765328_27 - - - - 0.0000000000000000000000000000000000007969 154.0
PYH2_k127_4765328_28 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000007245 147.0
PYH2_k127_4765328_29 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000001143 136.0
PYH2_k127_4765328_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 482.0
PYH2_k127_4765328_30 4Fe-4S ferredoxin iron-sulfur binding domain protein K02574 - - 0.0000000000000000000000000000003657 128.0
PYH2_k127_4765328_31 VIT family - - - 0.00000000000000000000000000002618 129.0
PYH2_k127_4765328_32 CoA-binding protein K06929 - - 0.000000000000000000000000003157 119.0
PYH2_k127_4765328_33 - - - - 0.0000000000000000000000000113 114.0
PYH2_k127_4765328_34 formate dehydrogenase (NAD+) activity K00176 - 1.2.7.3 0.000000000000000000001802 95.0
PYH2_k127_4765328_35 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000002797 79.0
PYH2_k127_4765328_36 Regulatory protein, FmdB family - - - 0.0000000000132 70.0
PYH2_k127_4765328_37 - - - - 0.00000000007037 64.0
PYH2_k127_4765328_38 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000002456 66.0
PYH2_k127_4765328_39 - - - - 0.000000002917 66.0
PYH2_k127_4765328_4 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 445.0
PYH2_k127_4765328_40 - - - - 0.00000000794 67.0
PYH2_k127_4765328_41 Pfam:DUF385 - - - 0.00000001401 64.0
PYH2_k127_4765328_42 PFAM O-Antigen - - - 0.000002383 59.0
PYH2_k127_4765328_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000008741 49.0
PYH2_k127_4765328_44 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0001959 44.0
PYH2_k127_4765328_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 419.0
PYH2_k127_4765328_6 histidine kinase A domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 401.0
PYH2_k127_4765328_7 cellulase activity K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 389.0
PYH2_k127_4765328_8 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 383.0
PYH2_k127_4765328_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 363.0
PYH2_k127_4777397_0 serine-type peptidase activity K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 354.0
PYH2_k127_4777397_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 341.0
PYH2_k127_4777397_10 - - - - 0.0000000000000000000000000000000000000000000000008863 181.0
PYH2_k127_4777397_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000004882 179.0
PYH2_k127_4777397_12 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000001523 151.0
PYH2_k127_4777397_13 PFAM flavin reductase domain protein FMN-binding K21185 - - 0.0000000000000000000000000000001492 129.0
PYH2_k127_4777397_14 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000001694 122.0
PYH2_k127_4777397_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000006816 113.0
PYH2_k127_4777397_16 Secreted repeat of unknown function - - - 0.000000000000000000000279 104.0
PYH2_k127_4777397_18 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000001124 81.0
PYH2_k127_4777397_19 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000002272 94.0
PYH2_k127_4777397_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 309.0
PYH2_k127_4777397_20 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000004251 85.0
PYH2_k127_4777397_21 TIGRFAM stage II sporulation protein D K06381 - - 0.000000000000001665 89.0
PYH2_k127_4777397_22 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000002228 70.0
PYH2_k127_4777397_23 Membrane - - - 0.00000000007214 76.0
PYH2_k127_4777397_25 glyoxalase III activity - - - 0.00002593 48.0
PYH2_k127_4777397_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000002627 252.0
PYH2_k127_4777397_4 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002065 249.0
PYH2_k127_4777397_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.000000000000000000000000000000000000000000000000000000000000000000002292 245.0
PYH2_k127_4777397_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000006484 242.0
PYH2_k127_4777397_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000242 229.0
PYH2_k127_4777397_8 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000801 212.0
PYH2_k127_4777397_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000004889 195.0
PYH2_k127_4785821_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 444.0
PYH2_k127_4785821_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008878 234.0
PYH2_k127_4785821_2 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000002429 156.0
PYH2_k127_4785821_3 denitrification pathway - - - 0.00000000000000000009483 97.0
PYH2_k127_4787545_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 565.0
PYH2_k127_4787545_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 470.0
PYH2_k127_4787545_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000003409 207.0
PYH2_k127_4787545_11 - - - - 0.0000000000000000000000000000000000000000005365 176.0
PYH2_k127_4787545_12 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.000000000000000000000000006383 113.0
PYH2_k127_4787545_13 Hypothetical methyltransferase - - - 0.0000000000000000000000009535 113.0
PYH2_k127_4787545_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000427 105.0
PYH2_k127_4787545_15 Belongs to the thiolase family - - - 0.000000000000000000000007549 101.0
PYH2_k127_4787545_16 protein serine/threonine phosphatase activity - - - 0.000000000000000000007749 109.0
PYH2_k127_4787545_17 acetyltransferase K17840 - 2.3.1.59 0.0000000000000000001857 90.0
PYH2_k127_4787545_18 Belongs to the binding-protein-dependent transport system permease family K10544,K10547 - - 0.0000000000000000006748 93.0
PYH2_k127_4787545_19 Flp Fap pilin component K02651 - - 0.000000001801 63.0
PYH2_k127_4787545_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 393.0
PYH2_k127_4787545_20 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.00001183 49.0
PYH2_k127_4787545_3 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 384.0
PYH2_k127_4787545_4 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 352.0
PYH2_k127_4787545_5 ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
PYH2_k127_4787545_6 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 306.0
PYH2_k127_4787545_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 291.0
PYH2_k127_4787545_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002729 278.0
PYH2_k127_4787545_9 TIGRFAM degV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000007814 223.0
PYH2_k127_4793064_0 MacB-like periplasmic core domain K02004 - - 8.205e-233 747.0
PYH2_k127_4793064_1 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 2.136e-221 707.0
PYH2_k127_4793064_10 Alpha/beta hydrolase family - - - 0.00000000000000000000000000002241 129.0
PYH2_k127_4793064_11 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000004636 112.0
PYH2_k127_4793064_12 Belongs to the UPF0255 family - - - 0.00000000000000000003632 94.0
PYH2_k127_4793064_13 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000002745 76.0
PYH2_k127_4793064_14 Pyridoxamine 5'-phosphate oxidase K05558 - - 0.00000000005044 64.0
PYH2_k127_4793064_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 636.0
PYH2_k127_4793064_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
PYH2_k127_4793064_4 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 292.0
PYH2_k127_4793064_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000011 271.0
PYH2_k127_4793064_6 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
PYH2_k127_4793064_7 FCD - - - 0.00000000000000000000000000000000000000000006187 168.0
PYH2_k127_4793064_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000004757 171.0
PYH2_k127_4793064_9 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000354 163.0
PYH2_k127_4820804_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 580.0
PYH2_k127_4820804_1 - - - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
PYH2_k127_4820804_2 - - - - 0.00000000000000000000000000000000000000000000000853 179.0
PYH2_k127_4820804_3 - - - - 0.000000000000001053 79.0
PYH2_k127_4825343_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
PYH2_k127_4825343_1 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009562 262.0
PYH2_k127_4825343_2 sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001585 238.0
PYH2_k127_483302_0 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 556.0
PYH2_k127_483302_1 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 506.0
PYH2_k127_483302_10 alanine dehydrogenase activity K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 349.0
PYH2_k127_483302_11 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 294.0
PYH2_k127_483302_12 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009549 269.0
PYH2_k127_483302_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000003219 226.0
PYH2_k127_483302_14 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000001037 218.0
PYH2_k127_483302_15 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000009564 164.0
PYH2_k127_483302_16 pfam nudix K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000007908 166.0
PYH2_k127_483302_17 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000004755 156.0
PYH2_k127_483302_18 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000007261 131.0
PYH2_k127_483302_19 Thioredoxin - - - 0.000000000000000000000000000000008063 132.0
PYH2_k127_483302_2 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 478.0
PYH2_k127_483302_20 CoA binding domain - - - 0.00000000000000000000000000006779 122.0
PYH2_k127_483302_21 Universal stress protein family - - - 0.0000000000000000000000000001902 120.0
PYH2_k127_483302_22 CAAX protease self-immunity - - - 0.000000000000000000000000001509 115.0
PYH2_k127_483302_23 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01185,K02395,K19223 - 3.2.1.17 0.0000000000000000000000004007 117.0
PYH2_k127_483302_24 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000002702 107.0
PYH2_k127_483302_25 iron-sulfur cluster assembly - - - 0.0000000000000000000001015 100.0
PYH2_k127_483302_26 quinone binding - - - 0.0000000000000000000009725 99.0
PYH2_k127_483302_27 CAAX protease self-immunity - - - 0.000000001835 61.0
PYH2_k127_483302_28 VIT family - - - 0.000000003998 60.0
PYH2_k127_483302_29 aminopeptidase activity - - - 0.0006003 51.0
PYH2_k127_483302_3 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 481.0
PYH2_k127_483302_4 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 467.0
PYH2_k127_483302_5 Aminotransferase class-V K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 429.0
PYH2_k127_483302_6 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 417.0
PYH2_k127_483302_7 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 413.0
PYH2_k127_483302_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 403.0
PYH2_k127_483302_9 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 364.0
PYH2_k127_4862964_1 PFAM MULE transposase, conserved domain - - - 0.0000000000000000000000000069 127.0
PYH2_k127_4862964_2 Domain of unknown function (DUF4445) - - - 0.00000000000000004447 82.0
PYH2_k127_4862964_3 metalloendopeptidase activity K03799 - - 0.00000000008097 65.0
PYH2_k127_4862964_4 Peptidase family M48 - - - 0.000000297 58.0
PYH2_k127_4875756_0 Glycogen debranching enzyme - - - 1.016e-232 734.0
PYH2_k127_4875756_1 PFAM glycosyl transferase, family 51 - - - 6.497e-231 746.0
PYH2_k127_4875756_10 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 343.0
PYH2_k127_4875756_11 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 334.0
PYH2_k127_4875756_12 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
PYH2_k127_4875756_13 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001231 286.0
PYH2_k127_4875756_14 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008702 282.0
PYH2_k127_4875756_15 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009403 243.0
PYH2_k127_4875756_16 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000001539 244.0
PYH2_k127_4875756_17 Domain of unknown function (DUF4350) - - - 0.00000000000000000000000000000000000000000000000000000000000000141 233.0
PYH2_k127_4875756_18 RDD family - - - 0.0000000000000000000000000000000000000000004742 168.0
PYH2_k127_4875756_19 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000003498 160.0
PYH2_k127_4875756_2 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 493.0
PYH2_k127_4875756_20 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000000004365 146.0
PYH2_k127_4875756_21 pathogenesis K02417,K02519 - - 0.0000000000000000000000007369 115.0
PYH2_k127_4875756_23 - - - - 0.00000001611 64.0
PYH2_k127_4875756_24 ThiS family - - - 0.00004901 49.0
PYH2_k127_4875756_25 23S rRNA-intervening sequence protein - - - 0.0001175 47.0
PYH2_k127_4875756_26 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0002999 44.0
PYH2_k127_4875756_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 492.0
PYH2_k127_4875756_4 glycoside hydrolase family 37 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 458.0
PYH2_k127_4875756_5 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 449.0
PYH2_k127_4875756_6 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 426.0
PYH2_k127_4875756_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 391.0
PYH2_k127_4875756_8 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 377.0
PYH2_k127_4875756_9 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 355.0
PYH2_k127_4879473_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 462.0
PYH2_k127_4879473_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 366.0
PYH2_k127_4879473_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005473 273.0
PYH2_k127_4879473_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000005558 234.0
PYH2_k127_4896690_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002342 280.0
PYH2_k127_4916316_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 541.0
PYH2_k127_4916316_1 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 380.0
PYH2_k127_4916316_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 368.0
PYH2_k127_4916316_3 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 347.0
PYH2_k127_4916316_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009812 277.0
PYH2_k127_4916316_5 - - - - 0.000000000000000000000000000000000000000000000000000000000002746 223.0
PYH2_k127_4916316_6 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000006908 83.0
PYH2_k127_4916316_7 Acetyltransferase GNAT family K00619 - 2.3.1.1 0.0006314 45.0
PYH2_k127_4917354_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 492.0
PYH2_k127_4917354_1 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 464.0
PYH2_k127_4917354_10 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000009402 114.0
PYH2_k127_4917354_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000002462 113.0
PYH2_k127_4917354_12 - - - - 0.000000000000000000000001114 104.0
PYH2_k127_4917354_13 Integral membrane protein TerC family K05794 - - 0.00000000000000000000003472 105.0
PYH2_k127_4917354_14 PFAM Cysteine-rich secretory protein family - - - 0.0000000000000001955 89.0
PYH2_k127_4917354_15 Cysteine-rich secretory protein family - - - 0.0000000000000007486 90.0
PYH2_k127_4917354_16 ethanolamine kinase activity K07251,K18844 - 2.7.1.89 0.00000004483 60.0
PYH2_k127_4917354_17 ethanolamine kinase activity K07251,K18844 - 2.7.1.89 0.0000001731 55.0
PYH2_k127_4917354_18 ATPase activity K16922 - - 0.000004005 60.0
PYH2_k127_4917354_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 439.0
PYH2_k127_4917354_3 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 423.0
PYH2_k127_4917354_4 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 314.0
PYH2_k127_4917354_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 293.0
PYH2_k127_4917354_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000003159 248.0
PYH2_k127_4917354_7 FCD K05799 - - 0.0000000000000000000000000000000000000000362 160.0
PYH2_k127_4917354_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000789 124.0
PYH2_k127_4917354_9 Cyclic nucleotide-monophosphate binding domain K04739 GO:0000003,GO:0000166,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0010721,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030551,GO:0030552,GO:0030554,GO:0030951,GO:0030952,GO:0031032,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141 - 0.0000000000000000000000000008188 131.0
PYH2_k127_4918498_0 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
PYH2_k127_4918498_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000002047 209.0
PYH2_k127_4918498_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000003161 181.0
PYH2_k127_4918498_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000009164 147.0
PYH2_k127_4921536_0 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 500.0
PYH2_k127_4921536_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 490.0
PYH2_k127_4921536_10 Glycosyl hydrolase catalytic core - - - 0.00000000000000000000000000000000000000000000001436 187.0
PYH2_k127_4921536_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000007523 181.0
PYH2_k127_4921536_12 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000002294 184.0
PYH2_k127_4921536_13 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000009728 188.0
PYH2_k127_4921536_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000002114 174.0
PYH2_k127_4921536_15 -O-antigen K13009,K18814 - - 0.000000000000000000000000006167 124.0
PYH2_k127_4921536_16 oligosaccharyl transferase activity - - - 0.00000000000000000000002548 115.0
PYH2_k127_4921536_17 WD40-like Beta Propeller Repeat K03641 - - 0.00000000001758 77.0
PYH2_k127_4921536_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 408.0
PYH2_k127_4921536_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 340.0
PYH2_k127_4921536_4 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 294.0
PYH2_k127_4921536_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 299.0
PYH2_k127_4921536_6 PFAM lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001724 291.0
PYH2_k127_4921536_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005063 265.0
PYH2_k127_4921536_8 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007009 254.0
PYH2_k127_4921536_9 response regulator receiver K07658,K07668 - - 0.0000000000000000000000000000000000000000000000003725 186.0
PYH2_k127_4973071_0 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 389.0
PYH2_k127_4973071_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000002676 169.0
PYH2_k127_4973071_2 Archaebacterial flagellin - - - 0.0000000006076 68.0
PYH2_k127_4973071_3 CBS domain containing protein K04767 - - 0.000000049 57.0
PYH2_k127_498563_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 318.0
PYH2_k127_498563_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000008476 105.0
PYH2_k127_498563_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000004065 87.0
PYH2_k127_498563_3 membrane transporter protein K07090 - - 0.000000002233 64.0
PYH2_k127_4985918_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 3.077e-200 637.0
PYH2_k127_4985918_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 451.0
PYH2_k127_4985918_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000007583 126.0
PYH2_k127_5025778_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.851e-269 835.0
PYH2_k127_5025778_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 496.0
PYH2_k127_5025778_10 heme binding - - - 0.0000000000000000000000000000026 133.0
PYH2_k127_5025778_11 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000000000002445 119.0
PYH2_k127_5025778_13 hydrolase K07025 - - 0.0000000000000000002045 97.0
PYH2_k127_5025778_14 - - - - 0.000000000000000007392 88.0
PYH2_k127_5025778_15 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000000006257 74.0
PYH2_k127_5025778_16 Domain of unknown function (DUF4340) - - - 0.000000006076 65.0
PYH2_k127_5025778_17 Belongs to the thioredoxin family K03671 - - 0.0000005188 54.0
PYH2_k127_5025778_18 PFAM MOSC domain - - - 0.0005311 42.0
PYH2_k127_5025778_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 488.0
PYH2_k127_5025778_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 334.0
PYH2_k127_5025778_4 Creatinase/Prolidase N-terminal domain K01262,K01271,K08326 GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 295.0
PYH2_k127_5025778_5 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007935 284.0
PYH2_k127_5025778_6 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005425 288.0
PYH2_k127_5025778_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008201 266.0
PYH2_k127_5025778_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000001401 211.0
PYH2_k127_5025778_9 - - - - 0.0000000000000000000000000000000000000004194 162.0
PYH2_k127_5054152_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 429.0
PYH2_k127_5054152_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 393.0
PYH2_k127_5054152_10 Methyltransferase - - - 0.0000002157 54.0
PYH2_k127_5054152_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 333.0
PYH2_k127_5054152_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002842 296.0
PYH2_k127_5054152_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002588 229.0
PYH2_k127_5054152_5 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000001365 226.0
PYH2_k127_5054152_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.00000000000000000000000000002958 131.0
PYH2_k127_5054152_7 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.00000000000000002124 85.0
PYH2_k127_5054152_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000002261 74.0
PYH2_k127_5054152_9 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000007273 68.0
PYH2_k127_506722_0 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 290.0
PYH2_k127_506722_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000005402 266.0
PYH2_k127_506722_2 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008862 235.0
PYH2_k127_506722_3 Ferritin-like - - - 0.000000000000000000000000000000000000000000000000000006287 198.0
PYH2_k127_506722_4 Haem-binding domain - - - 0.0000000000000000000000000000005765 129.0
PYH2_k127_506722_5 - - - - 0.000000000000000000000000009422 118.0
PYH2_k127_506722_6 NmrA-like family - - - 0.00000000000000237 78.0
PYH2_k127_5139321_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.123e-263 830.0
PYH2_k127_5139321_1 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
PYH2_k127_5139321_2 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000001767 201.0
PYH2_k127_5139321_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000001228 119.0
PYH2_k127_5139321_4 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000002923 111.0
PYH2_k127_5148010_0 Proposed role in polysaccahride synthesis K07077 - - 5.418e-284 882.0
PYH2_k127_5148010_1 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 400.0
PYH2_k127_5148010_2 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 367.0
PYH2_k127_5148010_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 346.0
PYH2_k127_5148010_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 323.0
PYH2_k127_5148010_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003473 274.0
PYH2_k127_5148010_6 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000001709 136.0
PYH2_k127_5148010_8 Protein of unknown function (DUF664) - - - 0.00000000131 66.0
PYH2_k127_5159769_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 618.0
PYH2_k127_5159769_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 438.0
PYH2_k127_5159769_2 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 336.0
PYH2_k127_5159769_3 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000006171 194.0
PYH2_k127_5159769_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000002333 96.0
PYH2_k127_5159769_5 Protein of unknown function (DUF1634) - - - 0.00000000000000007349 86.0
PYH2_k127_5164433_0 RNase_H superfamily - - - 1.47e-319 1002.0
PYH2_k127_5164433_1 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000003014 221.0
PYH2_k127_5164433_2 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000165 148.0
PYH2_k127_5164433_3 Dehydrogenase K06446 - - 0.0000000000000000000000000000000004646 134.0
PYH2_k127_5164433_4 - - - - 0.00000003876 55.0
PYH2_k127_5164433_5 - - - - 0.0000002493 52.0
PYH2_k127_518969_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 442.0
PYH2_k127_518969_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 419.0
PYH2_k127_518969_2 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001595 213.0
PYH2_k127_518969_3 Cytochrome c K17222 - - 0.0000000000000000000000001216 118.0
PYH2_k127_518969_4 FCD K05799,K14348 - - 0.0000000000006878 70.0
PYH2_k127_518969_5 Iron permease FTR1 family K07243 - - 0.000000000007323 76.0
PYH2_k127_5197762_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 546.0
PYH2_k127_5197762_1 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 469.0
PYH2_k127_5197762_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
PYH2_k127_5197762_11 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000009935 222.0
PYH2_k127_5197762_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000005626 212.0
PYH2_k127_5197762_13 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000005207 184.0
PYH2_k127_5197762_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 430.0
PYH2_k127_5197762_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 419.0
PYH2_k127_5197762_4 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 403.0
PYH2_k127_5197762_5 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 388.0
PYH2_k127_5197762_6 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 368.0
PYH2_k127_5197762_7 hmm pf00144 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 343.0
PYH2_k127_5197762_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 284.0
PYH2_k127_5197762_9 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004799 286.0
PYH2_k127_5228715_0 Belongs to the TtcA family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000007048 270.0
PYH2_k127_5228715_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000308 228.0
PYH2_k127_5228715_2 thiamine diphosphate biosynthetic process K03154 - - 0.0002794 47.0
PYH2_k127_5246598_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 513.0
PYH2_k127_5246598_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 369.0
PYH2_k127_5246598_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 347.0
PYH2_k127_5246598_3 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 311.0
PYH2_k127_5246932_0 Belongs to the UPF0255 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 304.0
PYH2_k127_5246932_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
PYH2_k127_5246932_2 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000003764 246.0
PYH2_k127_5246932_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000001293 211.0
PYH2_k127_5246932_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000008053 194.0
PYH2_k127_5246932_6 NMT1-like family K02051,K15553 - - 0.000000000004898 78.0
PYH2_k127_5246932_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.000008491 57.0
PYH2_k127_5246932_8 COG0006 Xaa-Pro aminopeptidase K01271,K15783 - 3.4.13.9,3.5.4.44 0.0002682 51.0
PYH2_k127_5250794_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 486.0
PYH2_k127_5250794_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 424.0
PYH2_k127_5250794_2 PFAM Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 414.0
PYH2_k127_5250794_3 'ABC-type dipeptide oligopeptide nickel transport K02033,K15581,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
PYH2_k127_5250794_4 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 338.0
PYH2_k127_5250794_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
PYH2_k127_5250794_6 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 324.0
PYH2_k127_5250794_7 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 312.0
PYH2_k127_5250794_8 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002284 267.0
PYH2_k127_5262944_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 485.0
PYH2_k127_5262944_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 389.0
PYH2_k127_5262944_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000008372 175.0
PYH2_k127_5262944_11 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000001057 179.0
PYH2_k127_5262944_12 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000003573 168.0
PYH2_k127_5262944_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000003417 158.0
PYH2_k127_5262944_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000001651 155.0
PYH2_k127_5262944_15 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000181 155.0
PYH2_k127_5262944_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000004254 143.0
PYH2_k127_5262944_17 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000007953 123.0
PYH2_k127_5262944_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000001717 118.0
PYH2_k127_5262944_19 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000001403 89.0
PYH2_k127_5262944_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
PYH2_k127_5262944_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002486 93.0
PYH2_k127_5262944_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000004666 84.0
PYH2_k127_5262944_22 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000818 81.0
PYH2_k127_5262944_23 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000008694 59.0
PYH2_k127_5262944_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
PYH2_k127_5262944_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
PYH2_k127_5262944_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000001723 228.0
PYH2_k127_5262944_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000012 221.0
PYH2_k127_5262944_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002229 214.0
PYH2_k127_5262944_8 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000006379 218.0
PYH2_k127_5262944_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001122 194.0
PYH2_k127_5263117_0 AAA ATPase domain - - - 6.503e-242 796.0
PYH2_k127_5263117_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
PYH2_k127_5263117_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000007942 59.0
PYH2_k127_5263117_2 collagen metabolic process K08677 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005032 295.0
PYH2_k127_5263117_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
PYH2_k127_5263117_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001488 221.0
PYH2_k127_5263117_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000003242 176.0
PYH2_k127_5263117_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000005256 138.0
PYH2_k127_5263117_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000009289 137.0
PYH2_k127_5263117_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000009884 83.0
PYH2_k127_5263117_9 F5/8 type C domain - - - 0.000000007288 66.0
PYH2_k127_5285790_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 440.0
PYH2_k127_5285790_1 Transposase - - - 0.00000000000000000000000000000000000006691 150.0
PYH2_k127_5285790_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000002652 96.0
PYH2_k127_5331964_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.16e-289 909.0
PYH2_k127_5331964_1 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 615.0
PYH2_k127_5345161_0 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000000000000000001212 120.0
PYH2_k127_5345161_1 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000007221 115.0
PYH2_k127_5345161_3 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.00000000000001031 73.0
PYH2_k127_5349664_0 PFAM ABC transporter related K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 530.0
PYH2_k127_5349664_1 virion core protein, lumpy skin disease virus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 401.0
PYH2_k127_5349664_2 Phage shock protein A, PspA K03969 - - 0.000000000000000000000000000000000000000000000004918 180.0
PYH2_k127_5349664_3 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000001239 163.0
PYH2_k127_5349664_4 Subtilase family - - - 0.00000000000000000000000002068 113.0
PYH2_k127_5349664_5 Psort location Cytoplasmic, score - - - 0.000000000000000002269 84.0
PYH2_k127_5349664_6 - - - - 0.00000000009278 73.0
PYH2_k127_5353975_0 GlcNAc-PI de-N-acetylase K16515 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 310.0
PYH2_k127_5353975_1 Aldolase/RraA K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002215 270.0
PYH2_k127_5353975_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000157 136.0
PYH2_k127_5353975_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000001164 87.0
PYH2_k127_5353975_4 phosphogluconate dehydrogenase (decarboxylating) activity - - - 0.000959 47.0
PYH2_k127_5368983_0 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 279.0
PYH2_k127_5368983_1 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000001493 232.0
PYH2_k127_5381235_0 A-macroglobulin receptor - - - 1.32e-242 786.0
PYH2_k127_5381235_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 584.0
PYH2_k127_5381235_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000002849 130.0
PYH2_k127_5381235_11 Putative ABC-transporter type IV - - - 0.0000000000000000000000000001012 119.0
PYH2_k127_5381235_12 NurA - - - 0.00000000000000002607 94.0
PYH2_k127_5381235_13 Trypsin-like peptidase domain K08372 - - 0.0000000004468 68.0
PYH2_k127_5381235_15 PDZ domain (Also known as DHR or GLGF) - - - 0.00002134 54.0
PYH2_k127_5381235_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 578.0
PYH2_k127_5381235_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 452.0
PYH2_k127_5381235_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 411.0
PYH2_k127_5381235_5 glucose sorbosone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 327.0
PYH2_k127_5381235_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
PYH2_k127_5381235_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000007019 216.0
PYH2_k127_5381235_8 MaoC like domain - - - 0.00000000000000000000000000000000000000002225 157.0
PYH2_k127_5381235_9 PFAM DinB family protein - - - 0.0000000000000000000000000000000000003255 147.0
PYH2_k127_5382692_0 Molydopterin dinucleotide binding domain K07306,K07812 - 1.7.2.3,1.8.5.3 3.69e-222 720.0
PYH2_k127_5382692_1 L-gulonolactone oxidase-like K00103 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0012505,GO:0016020,GO:0016051,GO:0016053,GO:0016491,GO:0016614,GO:0016899,GO:0019752,GO:0019852,GO:0019853,GO:0031090,GO:0031984,GO:0036094,GO:0042175,GO:0042364,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046364,GO:0046394,GO:0048037,GO:0050105,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:0098827,GO:1901265,GO:1901363,GO:1901576 1.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 325.0
PYH2_k127_5382692_2 Protease prsW family - - - 0.00000000000000000000000000000000003591 153.0
PYH2_k127_5382692_3 Similarity to COG0437 Fe-S-cluster-containing hydrogenase components 1(Evalue - - - 0.00000000000000124 76.0
PYH2_k127_5382692_4 PFAM Phospholipid glycerol acyltransferase - - - 0.0001075 47.0
PYH2_k127_5389099_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 357.0
PYH2_k127_5389099_10 Psort location CytoplasmicMembrane, score - - - 0.000000000001073 81.0
PYH2_k127_5389099_11 Bacterial membrane protein YfhO - - - 0.0000001239 57.0
PYH2_k127_5389099_12 Cell envelope-related transcriptional attenuator domain - - - 0.000001088 61.0
PYH2_k127_5389099_2 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 364.0
PYH2_k127_5389099_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
PYH2_k127_5389099_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000002135 247.0
PYH2_k127_5389099_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
PYH2_k127_5389099_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000001312 200.0
PYH2_k127_5389099_7 Glyoxalase-like domain - - - 0.0000000000000000000000000000000001646 145.0
PYH2_k127_5389099_8 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000003664 128.0
PYH2_k127_5389099_9 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000008317 106.0
PYH2_k127_5390010_0 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000317 115.0
PYH2_k127_5390010_1 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000001814 100.0
PYH2_k127_5390010_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000004648 83.0
PYH2_k127_5410830_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 599.0
PYH2_k127_5410830_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 559.0
PYH2_k127_5410830_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 327.0
PYH2_k127_5410830_11 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
PYH2_k127_5410830_12 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
PYH2_k127_5410830_13 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005385 267.0
PYH2_k127_5410830_14 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000002898 182.0
PYH2_k127_5410830_15 acetyltransferase - - - 0.000000000000000000000000000000000000000000009743 173.0
PYH2_k127_5410830_16 membrane - - - 0.000000000000000000000000000000000000000003505 174.0
PYH2_k127_5410830_17 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000001199 146.0
PYH2_k127_5410830_18 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000001938 143.0
PYH2_k127_5410830_19 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000001864 121.0
PYH2_k127_5410830_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 544.0
PYH2_k127_5410830_20 23S rRNA-intervening sequence protein - - - 0.0000000000000000002697 92.0
PYH2_k127_5410830_21 23S rRNA-intervening sequence protein - - - 0.00000000000001334 76.0
PYH2_k127_5410830_22 DinB family - - - 0.000000001181 67.0
PYH2_k127_5410830_23 Sulfatase-modifying factor enzyme 1 - - - 0.000000007754 62.0
PYH2_k127_5410830_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 526.0
PYH2_k127_5410830_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 499.0
PYH2_k127_5410830_5 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 467.0
PYH2_k127_5410830_6 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 462.0
PYH2_k127_5410830_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 442.0
PYH2_k127_5410830_8 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 414.0
PYH2_k127_5410830_9 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 392.0
PYH2_k127_5413322_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.685e-229 726.0
PYH2_k127_5413322_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 356.0
PYH2_k127_5413322_10 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000006402 109.0
PYH2_k127_5413322_11 23S rRNA-intervening sequence protein - - - 0.00000000000000000000002184 104.0
PYH2_k127_5413322_12 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000002526 64.0
PYH2_k127_5413322_2 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 356.0
PYH2_k127_5413322_3 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 348.0
PYH2_k127_5413322_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 334.0
PYH2_k127_5413322_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 313.0
PYH2_k127_5413322_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 295.0
PYH2_k127_5413322_7 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
PYH2_k127_5413322_8 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000000000000000000001197 192.0
PYH2_k127_5413322_9 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000001832 172.0
PYH2_k127_5470330_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 312.0
PYH2_k127_5470330_1 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000007425 228.0
PYH2_k127_5471987_0 TIGRFAM degV family protein - - - 0.000000000000000000000000000000000000000000001667 176.0
PYH2_k127_5471987_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000004342 119.0
PYH2_k127_5471987_2 COG3794 Plastocyanin - - - 0.0000007958 57.0
PYH2_k127_5471987_3 Alternative locus ID K01470 - 3.5.2.10 0.0008731 44.0
PYH2_k127_5525698_0 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 417.0
PYH2_k127_5525698_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 321.0
PYH2_k127_5525698_2 Acyl-coa dehydrogenase K00249 - 1.3.8.7 0.000000000000000002378 85.0
PYH2_k127_5626322_0 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 619.0
PYH2_k127_5626322_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 329.0
PYH2_k127_5626322_2 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 339.0
PYH2_k127_5626322_3 COG0395 ABC-type sugar transport system, permease component K02026,K10242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001679 283.0
PYH2_k127_5626322_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004067 273.0
PYH2_k127_5626322_5 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
PYH2_k127_5626322_6 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000006601 151.0
PYH2_k127_5626322_7 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000003776 149.0
PYH2_k127_5626322_8 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000002758 123.0
PYH2_k127_5626322_9 BTB And C-terminal Kelch K10457 - - 0.0000000000000000000004251 108.0
PYH2_k127_5634725_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.579e-200 631.0
PYH2_k127_5634725_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 557.0
PYH2_k127_5634725_10 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 356.0
PYH2_k127_5634725_11 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 344.0
PYH2_k127_5634725_12 PFAM helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 325.0
PYH2_k127_5634725_13 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 305.0
PYH2_k127_5634725_14 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006045 299.0
PYH2_k127_5634725_15 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005705 248.0
PYH2_k127_5634725_16 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 248.0
PYH2_k127_5634725_17 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000003006 243.0
PYH2_k127_5634725_18 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007655 234.0
PYH2_k127_5634725_19 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000001674 233.0
PYH2_k127_5634725_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 558.0
PYH2_k127_5634725_20 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000003155 216.0
PYH2_k127_5634725_21 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000002563 221.0
PYH2_k127_5634725_22 Lysin motif - - - 0.00000000000000000000000000000000000000000000000003503 194.0
PYH2_k127_5634725_23 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000004001 183.0
PYH2_k127_5634725_24 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000003341 175.0
PYH2_k127_5634725_25 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000001277 171.0
PYH2_k127_5634725_26 Domain of unknown function (DUF3368) K07066 - - 0.000000000000000000000000000000000000000000008295 167.0
PYH2_k127_5634725_27 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000001002 172.0
PYH2_k127_5634725_28 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000003819 167.0
PYH2_k127_5634725_29 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000002763 167.0
PYH2_k127_5634725_3 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 558.0
PYH2_k127_5634725_30 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000002378 156.0
PYH2_k127_5634725_31 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.0000000000000000000000000000003137 130.0
PYH2_k127_5634725_32 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.000000000000000000000000001527 117.0
PYH2_k127_5634725_33 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000007689 124.0
PYH2_k127_5634725_35 Uncharacterised protein family (UPF0175) - - - 0.00000000000000000000005862 100.0
PYH2_k127_5634725_36 Peptidoglycan-binding lysin domain - - - 0.000000000000002306 88.0
PYH2_k127_5634725_37 helicase - - - 0.000000000000005467 80.0
PYH2_k127_5634725_38 PFAM LysM domain - - - 0.00000000000001434 87.0
PYH2_k127_5634725_39 PFAM Integrase - - - 0.00000000000001773 77.0
PYH2_k127_5634725_4 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 496.0
PYH2_k127_5634725_40 PFAM helicase domain protein - - - 0.0000000000385 65.0
PYH2_k127_5634725_41 Thioredoxin-like - - - 0.000000007617 62.0
PYH2_k127_5634725_42 - - - - 0.00000002927 60.0
PYH2_k127_5634725_43 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000006193 64.0
PYH2_k127_5634725_5 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 505.0
PYH2_k127_5634725_6 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 505.0
PYH2_k127_5634725_7 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 463.0
PYH2_k127_5634725_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 387.0
PYH2_k127_5634725_9 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 387.0
PYH2_k127_5637830_0 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000006925 189.0
PYH2_k127_5637830_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000006598 129.0
PYH2_k127_5637830_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000009354 94.0
PYH2_k127_5650125_0 intracellular signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 532.0
PYH2_k127_5650125_1 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 428.0
PYH2_k127_5650125_10 O-methyltransferase, family 2 - - - 0.00000000000000000000000003567 121.0
PYH2_k127_5650125_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000006052 109.0
PYH2_k127_5650125_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000003606 92.0
PYH2_k127_5650125_14 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000004499 86.0
PYH2_k127_5650125_15 Cytochrome C oxidase, cbb3-type, subunit III K00406,K03889 - - 0.0000000009504 64.0
PYH2_k127_5650125_16 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000001389 53.0
PYH2_k127_5650125_17 Protein of unknown function (DUF2961) - - - 0.000001143 62.0
PYH2_k127_5650125_2 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 406.0
PYH2_k127_5650125_3 PFAM inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 377.0
PYH2_k127_5650125_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
PYH2_k127_5650125_5 Immune inhibitor A peptidase M6 K09607 - - 0.0000000000000000000000000000000000000000000000000001007 195.0
PYH2_k127_5650125_6 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000000002122 156.0
PYH2_k127_5650125_7 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.00000000000000000000000000000000000000002705 154.0
PYH2_k127_5650125_8 protein conserved in bacteria - - - 0.00000000000000000000000000001312 121.0
PYH2_k127_5650125_9 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000004672 119.0
PYH2_k127_5651267_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1314.0
PYH2_k127_5651267_1 Thiamine pyrophosphate enzyme, central domain K00158,K01576,K01652 - 1.2.3.3,2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 559.0
PYH2_k127_5651267_10 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001178 285.0
PYH2_k127_5651267_11 Reductive dehalogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003336 282.0
PYH2_k127_5651267_12 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004036 278.0
PYH2_k127_5651267_13 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003502 284.0
PYH2_k127_5651267_14 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005737 251.0
PYH2_k127_5651267_15 PFAM Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000006797 246.0
PYH2_k127_5651267_16 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000001377 219.0
PYH2_k127_5651267_17 PFAM Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000001174 217.0
PYH2_k127_5651267_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000001056 212.0
PYH2_k127_5651267_19 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000001036 199.0
PYH2_k127_5651267_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 496.0
PYH2_k127_5651267_20 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000004356 158.0
PYH2_k127_5651267_21 FCD - - - 0.00000000000000000000000000000001653 136.0
PYH2_k127_5651267_22 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000003166 138.0
PYH2_k127_5651267_23 OsmC-like protein K07397 - - 0.00000000000000000000000000001872 123.0
PYH2_k127_5651267_24 methyltransferase activity - - - 0.0000000000009902 70.0
PYH2_k127_5651267_25 aminopeptidase K01262 - 3.4.11.9 0.0000001016 64.0
PYH2_k127_5651267_26 thiamine-containing compound biosynthetic process - - - 0.000001034 61.0
PYH2_k127_5651267_27 DoxX K15977 - - 0.000001186 55.0
PYH2_k127_5651267_28 Cupin 2, conserved barrel domain protein - - - 0.0007654 48.0
PYH2_k127_5651267_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 434.0
PYH2_k127_5651267_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 438.0
PYH2_k127_5651267_5 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 396.0
PYH2_k127_5651267_6 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 364.0
PYH2_k127_5651267_7 oxidoreductase K00010,K16043 - 1.1.1.18,1.1.1.369,1.1.1.370 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 308.0
PYH2_k127_5651267_8 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 295.0
PYH2_k127_5651267_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
PYH2_k127_5676111_0 Magnesium chelatase, subunit ChlI K07391 - - 8.847e-223 701.0
PYH2_k127_5676111_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 461.0
PYH2_k127_5676111_2 CoA-transferase activity K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 381.0
PYH2_k127_5676111_3 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 322.0
PYH2_k127_5676111_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 296.0
PYH2_k127_5676111_5 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000001425 233.0
PYH2_k127_5676111_6 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000001224 175.0
PYH2_k127_5676111_7 Amidohydrolase family - - - 0.0000005356 55.0
PYH2_k127_5676111_8 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.00000598 52.0
PYH2_k127_5676406_0 - - - - 0.000000000000000000000000000002297 124.0
PYH2_k127_5676406_1 - - - - 0.00000000000000000000000007525 115.0
PYH2_k127_5676406_2 - - - - 0.00000000000000000005305 100.0
PYH2_k127_5676406_3 Pfam:DUF385 - - - 0.0000000000000000001163 94.0
PYH2_k127_5678320_0 exo-alpha-(2->6)-sialidase activity - - - 5.32e-219 696.0
PYH2_k127_5678320_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 403.0
PYH2_k127_5678320_10 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000004418 159.0
PYH2_k127_5678320_11 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000001279 130.0
PYH2_k127_5678320_12 - - - - 0.000000000000000000000000002056 122.0
PYH2_k127_5678320_13 Psort location CytoplasmicMembrane, score - - - 0.0003497 47.0
PYH2_k127_5678320_2 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 362.0
PYH2_k127_5678320_3 NAD-dependent epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 339.0
PYH2_k127_5678320_4 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 303.0
PYH2_k127_5678320_5 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002621 240.0
PYH2_k127_5678320_6 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000003537 216.0
PYH2_k127_5678320_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000008475 211.0
PYH2_k127_5678320_8 Endoribonuclease L-PSP K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000000004789 189.0
PYH2_k127_5678320_9 PFAM MerR family regulatory protein K22491 - - 0.0000000000000000000000000000000000000000009164 172.0
PYH2_k127_5689151_0 WD40 repeats K20332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 541.0
PYH2_k127_5689151_1 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002356 242.0
PYH2_k127_5689151_2 cellulose binding - - - 0.0000000000000000000000000006268 127.0
PYH2_k127_5689151_3 TIGRFAM YD repeat protein - - - 0.000000000007357 77.0
PYH2_k127_5689151_4 TIGRFAM YD repeat protein - - - 0.000000002218 69.0
PYH2_k127_5733072_0 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 520.0
PYH2_k127_5733072_1 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 277.0
PYH2_k127_5733072_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000002883 151.0
PYH2_k127_5733072_3 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000001663 106.0
PYH2_k127_5733072_4 Belongs to the peptidase S8 family K14645 - - 0.00000000004396 68.0
PYH2_k127_5733072_5 Subtilase family K14645 - - 0.000000004826 59.0
PYH2_k127_5733072_6 CarD-like/TRCF domain K07736 - - 0.00005972 45.0
PYH2_k127_5757838_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 617.0
PYH2_k127_5757838_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 299.0
PYH2_k127_5757838_10 carbohydrate transport K02027,K05813 - - 0.000000000000000000000000000000000000000004048 173.0
PYH2_k127_5757838_11 Stage II sporulation protein K21449 - - 0.00000000000000000000000000000000000000352 159.0
PYH2_k127_5757838_12 Redoxin - - - 0.000000000000000000000000000001369 123.0
PYH2_k127_5757838_13 carbohydrate transport K02027,K05813 - - 0.00000000000000000000000000001996 134.0
PYH2_k127_5757838_14 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000001676 114.0
PYH2_k127_5757838_15 PFAM ABC transporter - - - 0.00000000000004475 73.0
PYH2_k127_5757838_16 Subtilase family - - - 0.000000000001424 76.0
PYH2_k127_5757838_17 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0004026 45.0
PYH2_k127_5757838_2 PFAM basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001056 278.0
PYH2_k127_5757838_3 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002353 251.0
PYH2_k127_5757838_4 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007925 248.0
PYH2_k127_5757838_5 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001046 245.0
PYH2_k127_5757838_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000004801 237.0
PYH2_k127_5757838_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000006627 230.0
PYH2_k127_5757838_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000001829 214.0
PYH2_k127_5757838_9 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000002386 217.0
PYH2_k127_5766385_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 266.0
PYH2_k127_5766385_1 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000002549 267.0
PYH2_k127_5766385_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000524 239.0
PYH2_k127_5766385_3 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000154 205.0
PYH2_k127_5766385_4 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000001733 187.0
PYH2_k127_5766385_5 PFAM regulatory protein TetR - - - 0.00000000000000000000006913 106.0
PYH2_k127_5766385_6 Acyl-CoA synthetase K00666 - - 0.000007971 50.0
PYH2_k127_5766385_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0001846 44.0
PYH2_k127_5812853_0 ATPase AAA K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 457.0
PYH2_k127_5812853_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 469.0
PYH2_k127_5812853_10 Adenylate - - - 0.00000000000001001 87.0
PYH2_k127_5812853_11 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000007962 77.0
PYH2_k127_5812853_12 peptidyl-tyrosine sulfation - - - 0.0000008985 60.0
PYH2_k127_5812853_13 TPR repeat - - - 0.000302 48.0
PYH2_k127_5812853_14 transcriptional regulator, SARP family - - - 0.0007057 48.0
PYH2_k127_5812853_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 412.0
PYH2_k127_5812853_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 345.0
PYH2_k127_5812853_4 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 323.0
PYH2_k127_5812853_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 317.0
PYH2_k127_5812853_6 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000009736 205.0
PYH2_k127_5812853_7 AAA ATPase domain - - - 0.000000000000000002232 100.0
PYH2_k127_5812853_8 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000001898 96.0
PYH2_k127_5812853_9 Adenylate - - - 0.000000000000003467 81.0
PYH2_k127_5817666_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 4.497e-208 675.0
PYH2_k127_5817666_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 355.0
PYH2_k127_5817666_10 depolymerase - - - 0.000000000000002969 87.0
PYH2_k127_5817666_11 Transposase - - - 0.00001403 53.0
PYH2_k127_5817666_12 membrane protein, required for colicin V production - - - 0.00007398 52.0
PYH2_k127_5817666_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 353.0
PYH2_k127_5817666_3 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 319.0
PYH2_k127_5817666_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 325.0
PYH2_k127_5817666_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 308.0
PYH2_k127_5817666_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 299.0
PYH2_k127_5817666_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000001717 195.0
PYH2_k127_5817666_8 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000008699 177.0
PYH2_k127_5817666_9 esterase - - - 0.00000000000000000000000000000000000008081 155.0
PYH2_k127_585540_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.875e-237 746.0
PYH2_k127_585540_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 563.0
PYH2_k127_585540_2 Glycosyl transferase, WecB TagA CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
PYH2_k127_585540_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000001605 137.0
PYH2_k127_585540_4 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000302 143.0
PYH2_k127_585540_5 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000721 108.0
PYH2_k127_585540_6 Phage integrase family K04763 - - 0.0000000000000000000000007718 106.0
PYH2_k127_585540_7 DEAD DEAH box helicase K06877 - - 0.00000003348 63.0
PYH2_k127_585540_8 Phage integrase, N-terminal SAM-like domain - - - 0.00003284 48.0
PYH2_k127_585540_9 helix_turn_helix, Lux Regulon - - - 0.0004981 44.0
PYH2_k127_5857096_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 579.0
PYH2_k127_5857096_1 Homoserine dehydrogenase, NAD binding domain K18652 - 1.1.1.361 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 391.0
PYH2_k127_5857096_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 336.0
PYH2_k127_5857096_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 325.0
PYH2_k127_5857096_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 314.0
PYH2_k127_5857096_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004614 292.0
PYH2_k127_5867147_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 467.0
PYH2_k127_5867147_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 394.0
PYH2_k127_5867147_2 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000001908 145.0
PYH2_k127_5867147_3 - - - - 0.00008419 48.0
PYH2_k127_5872730_0 PFAM regulatory protein LuxR K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 356.0
PYH2_k127_5872730_1 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.00000000000000000000006526 102.0
PYH2_k127_5872730_2 - - - - 0.0000000000000004903 80.0
PYH2_k127_5873110_0 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 443.0
PYH2_k127_5873110_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
PYH2_k127_5873110_2 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 272.0
PYH2_k127_5873110_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.00000000000000000000000000004262 125.0
PYH2_k127_5873110_4 Fibronectin type III domain K03933 - - 0.00000000000000000004366 103.0
PYH2_k127_5921515_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 5.254e-209 677.0
PYH2_k127_5921515_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 508.0
PYH2_k127_5921515_10 - - - - 0.0000000000000000227 85.0
PYH2_k127_5921515_11 - - - - 0.00000000000003474 73.0
PYH2_k127_5921515_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 295.0
PYH2_k127_5921515_3 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 292.0
PYH2_k127_5921515_4 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000675 256.0
PYH2_k127_5921515_5 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000005876 239.0
PYH2_k127_5921515_6 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000001742 202.0
PYH2_k127_5921515_7 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000009659 200.0
PYH2_k127_5921515_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000007462 117.0
PYH2_k127_5921515_9 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000001734 89.0
PYH2_k127_5953414_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 349.0
PYH2_k127_5959796_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 505.0
PYH2_k127_5965697_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 452.0
PYH2_k127_5965697_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000003223 51.0
PYH2_k127_5979770_0 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 450.0
PYH2_k127_5979770_1 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 295.0
PYH2_k127_5979770_2 Cellulase (glycosyl hydrolase family 5) - - - 0.000000000000000000000000000000000000000006365 167.0
PYH2_k127_5998149_0 glutamate synthase, alpha subunit domain protein K00284 - 1.4.7.1 0.0 1259.0
PYH2_k127_5998149_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 591.0
PYH2_k127_5998149_10 - K02195 - - 0.0004444 50.0
PYH2_k127_5998149_11 phosphatase K20074 - 3.1.3.16 0.000778 46.0
PYH2_k127_5998149_2 Histidine kinase K00936,K01719,K01768,K02030,K02584,K10441,K13924,K20962 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 354.0
PYH2_k127_5998149_3 PFAM Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
PYH2_k127_5998149_4 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000005214 267.0
PYH2_k127_5998149_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000001607 226.0
PYH2_k127_5998149_6 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000001852 179.0
PYH2_k127_5998149_7 UPF0060 membrane protein K09771 - - 0.000000000000000000000000000000000000000000002189 168.0
PYH2_k127_5998149_8 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000003769 142.0
PYH2_k127_5998149_9 XdhC and CoxI family K07402 - - 0.000000000000005324 78.0
PYH2_k127_6034170_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 563.0
PYH2_k127_6034170_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 310.0
PYH2_k127_6034170_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 306.0
PYH2_k127_6034170_3 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.000000000000000000000000000000000000000000000000003949 188.0
PYH2_k127_6034170_4 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.0000000000000000000000000009925 116.0
PYH2_k127_6040350_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 608.0
PYH2_k127_6040350_1 PFAM 4Fe-4S binding domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000001724 239.0
PYH2_k127_6040350_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000002165 178.0
PYH2_k127_6040350_3 - - - - 0.00000000000000000000000000000001405 132.0
PYH2_k127_6040350_4 Sulphur transport K07112 - - 0.000000000000000000000000002906 124.0
PYH2_k127_6040350_5 component of anaerobic dehydrogenases - - - 0.00000000000000000000000005601 118.0
PYH2_k127_604085_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 456.0
PYH2_k127_604085_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 402.0
PYH2_k127_604085_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 332.0
PYH2_k127_604085_3 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 293.0
PYH2_k127_604085_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001642 287.0
PYH2_k127_604085_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002211 240.0
PYH2_k127_604085_6 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000006524 228.0
PYH2_k127_604085_7 Belongs to the ParB family K03497 - - 0.000000000000000002917 87.0
PYH2_k127_604085_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00001302 52.0
PYH2_k127_604085_9 - - - - 0.00003865 49.0
PYH2_k127_6058648_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1064.0
PYH2_k127_6058648_1 Belongs to the malate synthase family K01638 - 2.3.3.9 2.502e-229 721.0
PYH2_k127_6058648_10 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 394.0
PYH2_k127_6058648_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 382.0
PYH2_k127_6058648_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 375.0
PYH2_k127_6058648_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 361.0
PYH2_k127_6058648_14 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 307.0
PYH2_k127_6058648_15 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 317.0
PYH2_k127_6058648_16 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 309.0
PYH2_k127_6058648_17 TIGRFAM cell division protein FtsW K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 299.0
PYH2_k127_6058648_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 289.0
PYH2_k127_6058648_19 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 288.0
PYH2_k127_6058648_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 510.0
PYH2_k127_6058648_20 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 287.0
PYH2_k127_6058648_21 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000001012 244.0
PYH2_k127_6058648_22 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000001131 242.0
PYH2_k127_6058648_23 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000002758 239.0
PYH2_k127_6058648_24 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000414 233.0
PYH2_k127_6058648_25 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000005185 229.0
PYH2_k127_6058648_26 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000003202 196.0
PYH2_k127_6058648_27 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000002359 186.0
PYH2_k127_6058648_28 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000001026 171.0
PYH2_k127_6058648_29 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000001314 171.0
PYH2_k127_6058648_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 460.0
PYH2_k127_6058648_30 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000007539 168.0
PYH2_k127_6058648_31 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000738 162.0
PYH2_k127_6058648_32 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000002565 162.0
PYH2_k127_6058648_33 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000006692 158.0
PYH2_k127_6058648_34 NUDIX domain - - - 0.0000000000000000000000000000000000009994 144.0
PYH2_k127_6058648_35 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.000000000000000000000000000000000002746 142.0
PYH2_k127_6058648_36 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000008677 157.0
PYH2_k127_6058648_37 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000005694 145.0
PYH2_k127_6058648_38 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000001277 153.0
PYH2_k127_6058648_39 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000212 131.0
PYH2_k127_6058648_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 437.0
PYH2_k127_6058648_41 Mannosyltransferase (PIG-V) - - - 0.0000000000000000000000000000003436 138.0
PYH2_k127_6058648_42 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.00000000000000000000000000006661 129.0
PYH2_k127_6058648_43 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000004748 126.0
PYH2_k127_6058648_44 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.0000000000000000000000000004958 121.0
PYH2_k127_6058648_45 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000008705 128.0
PYH2_k127_6058648_46 regulation of translation K03530 - - 0.00000000000000000000000001956 116.0
PYH2_k127_6058648_47 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000001093 115.0
PYH2_k127_6058648_48 amino acid-binding ACT domain protein K04767 - - 0.00000000000000000000000364 108.0
PYH2_k127_6058648_49 PFAM NHL repeat containing protein - - - 0.0000000000000000000001248 97.0
PYH2_k127_6058648_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 434.0
PYH2_k127_6058648_51 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000001111 96.0
PYH2_k127_6058648_52 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000004505 97.0
PYH2_k127_6058648_54 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000003726 96.0
PYH2_k127_6058648_55 Isocitrate lyase family K01637 - 4.1.3.1 0.0000000000000004844 79.0
PYH2_k127_6058648_56 Belongs to the UPF0235 family K09131 - - 0.000000000000002053 80.0
PYH2_k127_6058648_57 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000333 76.0
PYH2_k127_6058648_58 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000002419 62.0
PYH2_k127_6058648_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 431.0
PYH2_k127_6058648_60 PFAM Prenyltransferase squalene oxidase - - - 0.0000004844 61.0
PYH2_k127_6058648_61 Major Facilitator Superfamily - - - 0.000003493 59.0
PYH2_k127_6058648_62 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00006768 55.0
PYH2_k127_6058648_63 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0001836 53.0
PYH2_k127_6058648_64 Histidine kinase - - - 0.0002321 53.0
PYH2_k127_6058648_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 411.0
PYH2_k127_6058648_8 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 410.0
PYH2_k127_6058648_9 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 400.0
PYH2_k127_60952_1 PFAM transposase, IS4 family protein K07481 - - 0.000000000000000002489 86.0
PYH2_k127_6095439_0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 409.0
PYH2_k127_6095439_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 391.0
PYH2_k127_6095439_10 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000005717 190.0
PYH2_k127_6095439_11 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000003993 172.0
PYH2_k127_6095439_12 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000004204 163.0
PYH2_k127_6095439_13 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000007981 150.0
PYH2_k127_6095439_14 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000003626 138.0
PYH2_k127_6095439_15 PFAM Cobalt transport protein K02008 - - 0.00000000000000000000000000003866 125.0
PYH2_k127_6095439_16 SdpI/YhfL protein family - - - 0.00000000000000001729 93.0
PYH2_k127_6095439_17 - - - - 0.0000000001189 72.0
PYH2_k127_6095439_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 332.0
PYH2_k127_6095439_3 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 323.0
PYH2_k127_6095439_4 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 291.0
PYH2_k127_6095439_5 PFAM GHMP kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000003007 273.0
PYH2_k127_6095439_6 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009288 258.0
PYH2_k127_6095439_7 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000001853 248.0
PYH2_k127_6095439_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000004087 211.0
PYH2_k127_6095439_9 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000002996 209.0
PYH2_k127_6121136_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 344.0
PYH2_k127_6121136_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008947 220.0
PYH2_k127_6121136_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000001886 210.0
PYH2_k127_6121136_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 0.00000000000000000000000000000000000000000000000004545 195.0
PYH2_k127_6121136_4 Belongs to the UPF0255 family - - - 0.0000000000000000000000000000000000000000009466 166.0
PYH2_k127_6121136_5 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000000000000000000001333 169.0
PYH2_k127_6121136_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000008596 121.0
PYH2_k127_6121136_7 Integrase core domain - - - 0.000000001353 59.0
PYH2_k127_6121136_8 COG0006 Xaa-Pro aminopeptidase K01271,K15783 - 3.4.13.9,3.5.4.44 0.0000005376 62.0
PYH2_k127_6236719_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 445.0
PYH2_k127_6236719_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 346.0
PYH2_k127_6236719_2 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002575 290.0
PYH2_k127_6236719_3 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003616 250.0
PYH2_k127_6236719_4 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000003068 125.0
PYH2_k127_6236719_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000002147 116.0
PYH2_k127_6236719_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.0000000000000000000006427 98.0
PYH2_k127_6236719_7 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000008642 88.0
PYH2_k127_6236719_9 Domain of unknown function (DUF4178) - - - 0.0000000000002262 81.0
PYH2_k127_6240203_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
PYH2_k127_6240203_1 Transposase - - - 0.00000000000000000000000001149 112.0
PYH2_k127_6240203_2 Protein of unknown function (DUF1475) - - - 0.0000000000000000000003485 100.0
PYH2_k127_6290906_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 433.0
PYH2_k127_6290906_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 378.0
PYH2_k127_6290906_11 Bacterial regulatory protein, Fis family - - - 0.000008244 55.0
PYH2_k127_6290906_12 - - - - 0.00007865 48.0
PYH2_k127_6290906_2 TIGRFAM capsular exopolysaccharide family K08253 - 2.7.10.2 0.00000000000000000000000000000000000000000000000000000000000000000000006401 246.0
PYH2_k127_6290906_3 dihydrofolate reductase activity K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001682 240.0
PYH2_k127_6290906_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000002304 212.0
PYH2_k127_6290906_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000001087 206.0
PYH2_k127_6290906_6 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000002374 175.0
PYH2_k127_6290906_7 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000007414 166.0
PYH2_k127_6290906_8 PFAM lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000000008195 124.0
PYH2_k127_6290906_9 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000001169 98.0
PYH2_k127_63080_0 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 422.0
PYH2_k127_63080_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 342.0
PYH2_k127_63080_10 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003885 238.0
PYH2_k127_63080_2 Histidine kinase K00936,K02030,K10441,K13924,K20962 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 334.0
PYH2_k127_63080_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 324.0
PYH2_k127_63080_4 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 316.0
PYH2_k127_63080_5 PFAM response regulator receiver K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009152 276.0
PYH2_k127_63080_6 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008381 287.0
PYH2_k127_63080_7 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000003338 269.0
PYH2_k127_63080_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001194 252.0
PYH2_k127_63080_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
PYH2_k127_63105_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 6.112e-243 760.0
PYH2_k127_63105_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 5.118e-236 753.0
PYH2_k127_63105_10 gntR family K05799 - - 0.00000000000000000000000000000000000002257 153.0
PYH2_k127_63105_11 Protein of unknown function (DUF559) - - - 0.000000000000000008435 87.0
PYH2_k127_63105_12 EamA-like transporter family - - - 0.000000144 57.0
PYH2_k127_63105_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 611.0
PYH2_k127_63105_3 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 393.0
PYH2_k127_63105_4 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 315.0
PYH2_k127_63105_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 303.0
PYH2_k127_63105_6 CO dehydrogenase flavoprotein C-terminal domain K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005666 248.0
PYH2_k127_63105_7 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000003461 180.0
PYH2_k127_63105_8 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000000000346 169.0
PYH2_k127_63105_9 Cupin domain - - - 0.00000000000000000000000000000000000001576 147.0
PYH2_k127_6345086_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 413.0
PYH2_k127_6345086_1 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 335.0
PYH2_k127_6345086_2 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 297.0
PYH2_k127_6345086_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002326 214.0
PYH2_k127_6345086_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000002628 171.0
PYH2_k127_6345086_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000002168 141.0
PYH2_k127_6345086_6 Transketolase, central region K00615 - 2.2.1.1 0.000000000000000000000000001056 119.0
PYH2_k127_6351843_0 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.571e-248 779.0
PYH2_k127_6351843_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 1.306e-220 701.0
PYH2_k127_6351843_10 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000001802 211.0
PYH2_k127_6351843_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000246 204.0
PYH2_k127_6351843_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000001991 173.0
PYH2_k127_6351843_13 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000004176 162.0
PYH2_k127_6351843_15 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000005653 121.0
PYH2_k127_6351843_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000001303 119.0
PYH2_k127_6351843_17 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000007211 109.0
PYH2_k127_6351843_18 Anti-sigma-K factor rskA - - - 0.000000000000000002343 94.0
PYH2_k127_6351843_19 - - - - 0.000000000003819 71.0
PYH2_k127_6351843_2 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 524.0
PYH2_k127_6351843_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001794 66.0
PYH2_k127_6351843_21 regulatory protein, FmdB family - - - 0.00000000122 63.0
PYH2_k127_6351843_22 - - - - 0.000009288 53.0
PYH2_k127_6351843_3 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 430.0
PYH2_k127_6351843_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 353.0
PYH2_k127_6351843_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 316.0
PYH2_k127_6351843_6 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 336.0
PYH2_k127_6351843_7 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 314.0
PYH2_k127_6351843_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 311.0
PYH2_k127_6351843_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 296.0
PYH2_k127_636500_0 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 613.0
PYH2_k127_636500_1 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 385.0
PYH2_k127_636500_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003894 278.0
PYH2_k127_6368575_0 solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 423.0
PYH2_k127_6368575_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 406.0
PYH2_k127_6368575_2 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 382.0
PYH2_k127_6368575_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 373.0
PYH2_k127_6368575_4 Binding-protein-dependent transport system inner membrane component K02025,K10118,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 339.0
PYH2_k127_6368575_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 325.0
PYH2_k127_6368575_6 transposase activity - - - 0.0000000001133 63.0
PYH2_k127_6423271_0 TIGRFAM small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000625 265.0
PYH2_k127_6423271_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000003073 226.0
PYH2_k127_6423271_2 4-vinyl reductase, 4VR K07013,K17763 - - 0.0000000000000000000000000000000006691 138.0
PYH2_k127_6423271_3 Histidine kinase - - - 0.000000000005376 76.0
PYH2_k127_6429702_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 392.0
PYH2_k127_6429702_1 Protein of unknown function (DUF664) - - - 0.0000000000000001401 87.0
PYH2_k127_6429702_2 Iron permease FTR1 family K07243 - - 0.00004984 51.0
PYH2_k127_6445464_0 cobalamin binding - - - 0.0 1753.0
PYH2_k127_6445464_1 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 370.0
PYH2_k127_6445464_2 NAD NADP octopine nopaline K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 326.0
PYH2_k127_6445464_3 Transcriptional regulator (RpiR family) - - - 0.0000000000000000000000000000000000000000000000002544 187.0
PYH2_k127_6445464_4 GYD domain - - - 0.00000000000000000000000000000002935 128.0
PYH2_k127_6445464_5 transposition K07497 - - 0.00000000001628 65.0
PYH2_k127_6455895_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.77e-227 718.0
PYH2_k127_6455895_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 475.0
PYH2_k127_6455895_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000002078 108.0
PYH2_k127_6455895_11 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000002136 115.0
PYH2_k127_6455895_12 Binds the 23S rRNA K02909 - - 0.00000000000000000000002294 110.0
PYH2_k127_6455895_13 Transposase IS200 like - - - 0.000000000000000007265 86.0
PYH2_k127_6455895_14 Cold-shock protein K03704 - - 0.00000000000001481 74.0
PYH2_k127_6455895_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000002452 69.0
PYH2_k127_6455895_16 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000001163 64.0
PYH2_k127_6455895_17 to M. xanthus CarD K07736 - - 0.000000001377 66.0
PYH2_k127_6455895_18 - - - - 0.00001629 48.0
PYH2_k127_6455895_19 - - - - 0.00001721 57.0
PYH2_k127_6455895_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 419.0
PYH2_k127_6455895_20 membrane K08978 - - 0.00003266 51.0
PYH2_k127_6455895_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 301.0
PYH2_k127_6455895_4 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
PYH2_k127_6455895_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004029 248.0
PYH2_k127_6455895_6 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000003219 237.0
PYH2_k127_6455895_7 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000002745 180.0
PYH2_k127_6455895_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000007299 124.0
PYH2_k127_6493091_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 500.0
PYH2_k127_6493091_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.00000000000000000000000000000003901 130.0
PYH2_k127_6493091_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000008687 68.0
PYH2_k127_6493091_3 - - - - 0.00002329 52.0
PYH2_k127_6508694_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 523.0
PYH2_k127_6508694_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 469.0
PYH2_k127_6508694_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000003487 168.0
PYH2_k127_6508694_11 XdhC and CoxI family - - - 0.000000000000000000000000000000000004421 139.0
PYH2_k127_6508694_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000001344 142.0
PYH2_k127_6508694_13 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.00000000000001009 80.0
PYH2_k127_6508694_14 Acetyltransferase (GNAT) domain - - - 0.00000000000005853 81.0
PYH2_k127_6508694_15 - - - - 0.00000000000223 79.0
PYH2_k127_6508694_16 Armadillo/beta-catenin-like repeats - - - 0.00000000003542 74.0
PYH2_k127_6508694_17 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04771 GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 0.00000142 60.0
PYH2_k127_6508694_19 DinB superfamily - - - 0.00009255 51.0
PYH2_k127_6508694_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 455.0
PYH2_k127_6508694_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00009614 54.0
PYH2_k127_6508694_21 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00009787 45.0
PYH2_k127_6508694_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 349.0
PYH2_k127_6508694_4 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 288.0
PYH2_k127_6508694_5 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001132 250.0
PYH2_k127_6508694_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
PYH2_k127_6508694_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000007882 216.0
PYH2_k127_6508694_8 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000602 184.0
PYH2_k127_6508694_9 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000001507 167.0
PYH2_k127_6523578_0 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 327.0
PYH2_k127_6523578_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000002031 228.0
PYH2_k127_6523578_2 response regulator K02282,K07705 - - 0.0000000000000000000000004738 110.0
PYH2_k127_6523578_3 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000227 110.0
PYH2_k127_6523578_4 integral membrane protein - - - 0.0000000000000298 79.0
PYH2_k127_6523578_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000003485 62.0
PYH2_k127_6523578_6 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00001962 50.0
PYH2_k127_6544609_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
PYH2_k127_6544609_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K02827 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002559 265.0
PYH2_k127_6544609_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
PYH2_k127_6544609_3 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002096 220.0
PYH2_k127_6544609_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000003314 181.0
PYH2_k127_6544609_5 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000004181 162.0
PYH2_k127_6544609_6 - - - - 0.000000001145 64.0
PYH2_k127_6563425_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 583.0
PYH2_k127_6563425_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 438.0
PYH2_k127_6563425_2 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 334.0
PYH2_k127_6563425_3 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000002668 195.0
PYH2_k127_6563425_4 TIGRFAM MazG family protein K02499 - - 0.00000000000000000000000000000000000000000000006218 182.0
PYH2_k127_6563425_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000003091 163.0
PYH2_k127_6563425_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000002695 93.0
PYH2_k127_6567059_0 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 570.0
PYH2_k127_6567059_1 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 352.0
PYH2_k127_6567059_2 Glycosyl transferase family 21 - - - 0.000000000000000002652 89.0
PYH2_k127_6567059_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000001157 61.0
PYH2_k127_6567059_4 - - - - 0.00001508 53.0
PYH2_k127_6580878_0 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 465.0
PYH2_k127_6580878_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 374.0
PYH2_k127_6580878_10 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000000005865 188.0
PYH2_k127_6580878_11 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000001566 182.0
PYH2_k127_6580878_12 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000005929 179.0
PYH2_k127_6580878_13 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000009944 168.0
PYH2_k127_6580878_14 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000101 138.0
PYH2_k127_6580878_15 ROK family K00847 - 2.7.1.4 0.000000000000001218 80.0
PYH2_k127_6580878_17 hydrolase (HAD superfamily) K07025 - - 0.0000005522 59.0
PYH2_k127_6580878_18 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.0000006026 61.0
PYH2_k127_6580878_2 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 322.0
PYH2_k127_6580878_3 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 303.0
PYH2_k127_6580878_4 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
PYH2_k127_6580878_5 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000858 293.0
PYH2_k127_6580878_6 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004363 288.0
PYH2_k127_6580878_7 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001333 288.0
PYH2_k127_6580878_8 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004646 282.0
PYH2_k127_6580878_9 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.00000000000000000000000000000000000000000000000000003988 198.0
PYH2_k127_6590467_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 512.0
PYH2_k127_6590467_1 Cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009473 285.0
PYH2_k127_6590467_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.00000000000000000000000000000001475 130.0
PYH2_k127_6590467_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000003767 68.0
PYH2_k127_6599484_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 552.0
PYH2_k127_6599484_1 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 409.0
PYH2_k127_6599484_2 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 388.0
PYH2_k127_6599484_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 293.0
PYH2_k127_6599484_4 WD domain, G-beta repeat - - - 0.000000000000000000000000003876 125.0
PYH2_k127_6623240_0 nitrous-oxide reductase activity K00376 - 1.7.2.4 3.465e-288 898.0
PYH2_k127_6623240_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 7.378e-199 644.0
PYH2_k127_6623240_10 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000005324 206.0
PYH2_k127_6623240_11 glycogen (starch) synthase activity K00703,K00754 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000005669 209.0
PYH2_k127_6623240_12 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000003863 199.0
PYH2_k127_6623240_13 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000000000002329 181.0
PYH2_k127_6623240_14 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000766 176.0
PYH2_k127_6623240_15 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000003096 157.0
PYH2_k127_6623240_16 NUDIX hydrolase - - - 0.000000000000000000000000000000000679 138.0
PYH2_k127_6623240_17 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000009968 141.0
PYH2_k127_6623240_18 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000001192 127.0
PYH2_k127_6623240_19 Parallel beta-helix repeats - - - 0.0000000000000000000000000000003793 141.0
PYH2_k127_6623240_2 dna ligase K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 3.413e-198 632.0
PYH2_k127_6623240_20 Cytochrome c K03611 - - 0.0000000000000000000000000000008391 126.0
PYH2_k127_6623240_21 NosL K19342 - - 0.00000000000000000000000000185 119.0
PYH2_k127_6623240_22 membrane - - - 0.00000000000000000001466 105.0
PYH2_k127_6623240_23 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000001626 91.0
PYH2_k127_6623240_24 Staphylococcal nuclease homologues K16561 - - 0.0000000000000000468 89.0
PYH2_k127_6623240_25 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000003189 63.0
PYH2_k127_6623240_26 O-Antigen ligase - - - 0.00005688 55.0
PYH2_k127_6623240_27 PFAM Tetratricopeptide repeat - - - 0.0001034 54.0
PYH2_k127_6623240_28 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.0002629 52.0
PYH2_k127_6623240_29 protein involved in exopolysaccharide biosynthesis - - - 0.0002645 52.0
PYH2_k127_6623240_3 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 596.0
PYH2_k127_6623240_4 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
PYH2_k127_6623240_5 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 533.0
PYH2_k127_6623240_6 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 378.0
PYH2_k127_6623240_7 Hsp70 protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 312.0
PYH2_k127_6623240_8 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009693 268.0
PYH2_k127_6623240_9 - K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000001656 236.0
PYH2_k127_6623844_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 494.0
PYH2_k127_6623844_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 350.0
PYH2_k127_6623844_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000001254 120.0
PYH2_k127_6623844_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0005343 46.0
PYH2_k127_664792_0 intracellular signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 522.0
PYH2_k127_664792_1 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 387.0
PYH2_k127_6661400_0 Belongs to the transketolase family K00615 - 2.2.1.1 4.195e-321 995.0
PYH2_k127_6661400_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 8.065e-270 859.0
PYH2_k127_6661400_10 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 429.0
PYH2_k127_6661400_11 ABC transporter K02013,K05776 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 393.0
PYH2_k127_6661400_12 carbohydrate kinase FGGY K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 381.0
PYH2_k127_6661400_13 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 317.0
PYH2_k127_6661400_14 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000128 294.0
PYH2_k127_6661400_15 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006824 279.0
PYH2_k127_6661400_16 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000323 275.0
PYH2_k127_6661400_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000002095 269.0
PYH2_k127_6661400_18 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009747 270.0
PYH2_k127_6661400_19 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001282 264.0
PYH2_k127_6661400_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.586e-232 728.0
PYH2_k127_6661400_20 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001795 250.0
PYH2_k127_6661400_21 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000002128 247.0
PYH2_k127_6661400_22 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000003054 241.0
PYH2_k127_6661400_23 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000001358 202.0
PYH2_k127_6661400_24 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000012 195.0
PYH2_k127_6661400_25 Protein of unknown function (DUF1361) - - - 0.000000000000000000000000000000000000000000000000000002094 200.0
PYH2_k127_6661400_26 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.000000000000000000000000000000000000000000008158 170.0
PYH2_k127_6661400_27 Fic/DOC family K07341 - - 0.0000000000000000000000000000000000000008654 154.0
PYH2_k127_6661400_28 NIPSNAP - - - 0.00000000000000000000000000000000000003892 146.0
PYH2_k127_6661400_29 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000000000000003192 133.0
PYH2_k127_6661400_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.321e-224 707.0
PYH2_k127_6661400_30 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000005667 89.0
PYH2_k127_6661400_31 - - - - 0.00001321 49.0
PYH2_k127_6661400_32 PFAM BNR Asp-box repeat - - - 0.0004141 52.0
PYH2_k127_6661400_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.175e-211 667.0
PYH2_k127_6661400_5 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 1.023e-208 671.0
PYH2_k127_6661400_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 599.0
PYH2_k127_6661400_7 PFAM peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 582.0
PYH2_k127_6661400_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 552.0
PYH2_k127_6661400_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 476.0
PYH2_k127_6671599_0 thiamine transport K02011 - - 9.649e-243 771.0
PYH2_k127_6671599_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 377.0
PYH2_k127_6671599_2 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 331.0
PYH2_k127_6671599_3 alcohol dehydrogenase K22231 - - 0.000000000000000009071 86.0
PYH2_k127_6694442_0 ethanolamine catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 326.0
PYH2_k127_6694442_1 ethanolamine catabolic process K04024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 309.0
PYH2_k127_6694442_2 protein domain associated with K03595,K06883,K06946 - - 0.0000000000000000000000000000000000000000000000000006023 197.0
PYH2_k127_6694442_3 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000000002587 156.0
PYH2_k127_6694442_4 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000009461 80.0
PYH2_k127_6694442_5 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000007826 74.0
PYH2_k127_6694442_6 - - - - 0.0000001472 59.0
PYH2_k127_6694442_7 - - - - 0.00006939 52.0
PYH2_k127_6694442_8 Cobalamin adenosyltransferase K04032 - 2.5.1.17 0.0002844 47.0
PYH2_k127_6705015_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.19e-235 741.0
PYH2_k127_6705015_1 Gamma-glutamyltranspeptidase 2-like K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 545.0
PYH2_k127_6705015_10 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000001042 197.0
PYH2_k127_6705015_11 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000004496 163.0
PYH2_k127_6705015_12 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000271 157.0
PYH2_k127_6705015_13 OpgC protein - - - 0.000000000000000000000000000000000000001876 162.0
PYH2_k127_6705015_14 Membrane K07149 - - 0.00000000000000000000000000000000000001187 152.0
PYH2_k127_6705015_15 Ribosomal protein L11 methyltransferase (PrmA) K05929 - 2.1.1.103 0.0000000000000000000000000000000000000138 150.0
PYH2_k127_6705015_16 deoxyhypusine monooxygenase activity - - - 0.0000001143 63.0
PYH2_k127_6705015_17 - - - - 0.0005807 50.0
PYH2_k127_6705015_2 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 517.0
PYH2_k127_6705015_3 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 465.0
PYH2_k127_6705015_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 372.0
PYH2_k127_6705015_5 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 353.0
PYH2_k127_6705015_6 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 347.0
PYH2_k127_6705015_7 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007242 250.0
PYH2_k127_6705015_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001588 248.0
PYH2_k127_6705015_9 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 246.0
PYH2_k127_6721320_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 377.0
PYH2_k127_6721320_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001204 244.0
PYH2_k127_6721320_2 rRNA (uridine-N3-)-methyltransferase activity K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000001629 216.0
PYH2_k127_6721320_3 Histidine kinase K07777,K19661,K21405 - 2.7.13.3 0.0000000000000000000000000000000000000000000001495 190.0
PYH2_k127_6721320_4 virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity catalytic activity a phosphatidylcholine H(2)O 1,2- diacylglycerol choline phosphate K01114 GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575 3.1.4.3 0.000000000000001707 79.0
PYH2_k127_6721320_5 Ribosomal protein L11 methyltransferase K02687 - - 0.00000008369 57.0
PYH2_k127_6721320_6 PFAM Polysulphide reductase, NrfD - - - 0.0009015 46.0
PYH2_k127_672163_0 PFAM extracellular solute-binding protein family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 555.0
PYH2_k127_672163_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 385.0
PYH2_k127_672163_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007917 263.0
PYH2_k127_6732495_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000006266 239.0
PYH2_k127_6732495_1 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000003762 163.0
PYH2_k127_6732495_2 TAP-like protein - - - 0.000007835 51.0
PYH2_k127_6739454_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
PYH2_k127_6739454_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000001153 221.0
PYH2_k127_675019_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.089e-227 726.0
PYH2_k127_675019_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 347.0
PYH2_k127_675019_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 335.0
PYH2_k127_675019_3 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000003962 175.0
PYH2_k127_675019_4 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.000000000000000000000000000000000000002714 147.0
PYH2_k127_6753517_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.084e-278 869.0
PYH2_k127_6753517_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 391.0
PYH2_k127_6753517_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 331.0
PYH2_k127_6753517_3 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000304 262.0
PYH2_k127_6753517_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000005283 202.0
PYH2_k127_6753517_5 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000533 122.0
PYH2_k127_6753517_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000002022 97.0
PYH2_k127_6753517_7 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.0000000000000001274 89.0
PYH2_k127_6753517_8 Belongs to the UPF0758 family K03630 - - 0.00000002365 59.0
PYH2_k127_6753517_9 Protein of unknown function (DUF2961) - - - 0.0000002572 64.0
PYH2_k127_6777221_0 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000004106 208.0
PYH2_k127_6777221_1 XRE family transcriptional regulator K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000003497 188.0
PYH2_k127_6777221_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000003847 151.0
PYH2_k127_6818129_0 PFAM ABC transporter related K06147 - - 1.478e-235 744.0
PYH2_k127_6818129_1 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 318.0
PYH2_k127_6818129_2 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000004074 204.0
PYH2_k127_6818129_3 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000004132 189.0
PYH2_k127_6818129_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000001297 186.0
PYH2_k127_6818129_5 Major facilitator superfamily K08161 - - 0.000000000000001374 89.0
PYH2_k127_6818129_6 TIGRFAM outer membrane autotransporter barrel domain - - - 0.00000000006326 69.0
PYH2_k127_6818129_7 Uncharacterized metal-binding protein (DUF2227) - - - 0.00000000206 66.0
PYH2_k127_6818129_8 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.00000001424 59.0
PYH2_k127_6818129_9 denitrification pathway K02569,K15876 - - 0.00003558 54.0
PYH2_k127_6827443_0 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
PYH2_k127_6827443_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000009851 121.0
PYH2_k127_6827443_2 PFAM CAAX amino terminal protease family K07052 - - 0.00000000000000001924 92.0
PYH2_k127_6834492_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000004923 231.0
PYH2_k127_6834492_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000006822 202.0
PYH2_k127_6834492_2 response regulator K02282,K07705 - - 0.000000000000000000000000001115 118.0
PYH2_k127_6834492_3 PFAM Transglycosylase-associated protein - - - 0.00001613 51.0
PYH2_k127_6834492_4 Por secretion system C-terminal sorting domain-containing protein - - - 0.00005288 55.0
PYH2_k127_6855238_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 420.0
PYH2_k127_6855238_1 amidohydrolase K03392,K07045 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 371.0
PYH2_k127_6855238_10 HEPN domain - - - 0.000006736 51.0
PYH2_k127_6855238_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003617 258.0
PYH2_k127_6855238_3 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001264 250.0
PYH2_k127_6855238_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001952 241.0
PYH2_k127_6855238_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000001939 200.0
PYH2_k127_6855238_6 PFAM DNA polymerase beta domain protein region - - - 0.00000000000000000000007556 102.0
PYH2_k127_6855238_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000005278 100.0
PYH2_k127_6855238_8 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000001267 79.0
PYH2_k127_6855238_9 PFAM HEPN domain - - - 0.0000000000002328 72.0
PYH2_k127_6860745_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 474.0
PYH2_k127_6860745_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000002602 217.0
PYH2_k127_6860745_2 XRE family transcriptional regulator K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000002833 201.0
PYH2_k127_6864256_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 614.0
PYH2_k127_6864256_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000001055 221.0
PYH2_k127_6864256_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000007627 209.0
PYH2_k127_6879999_0 Sigma-70, region 4 type 2 K11618 - - 0.000000000000000000000000000000000000000000000000000000000000001064 225.0
PYH2_k127_6879999_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000008686 186.0
PYH2_k127_6888153_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000008487 224.0
PYH2_k127_6888153_1 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000004545 153.0
PYH2_k127_6888153_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000797 152.0
PYH2_k127_6890968_0 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000001797 194.0
PYH2_k127_6890968_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000008673 172.0
PYH2_k127_6890968_2 - - - - 0.0000000000000000000000000000002465 126.0
PYH2_k127_6890968_3 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000306 130.0
PYH2_k127_6890968_4 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000002247 111.0
PYH2_k127_6890968_5 Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria K10534 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0016491,GO:0016661,GO:0046857,GO:0050464,GO:0055114 1.7.1.1,1.7.1.2,1.7.1.3 0.00003119 51.0
PYH2_k127_6899211_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1239.0
PYH2_k127_6899211_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 7.995e-289 912.0
PYH2_k127_6899211_10 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 358.0
PYH2_k127_6899211_11 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 351.0
PYH2_k127_6899211_12 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 357.0
PYH2_k127_6899211_13 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 347.0
PYH2_k127_6899211_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 307.0
PYH2_k127_6899211_15 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 300.0
PYH2_k127_6899211_16 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 289.0
PYH2_k127_6899211_17 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 285.0
PYH2_k127_6899211_18 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 282.0
PYH2_k127_6899211_19 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001242 278.0
PYH2_k127_6899211_2 Alpha-2-macroglobulin family K06894 - - 8.701e-268 886.0
PYH2_k127_6899211_20 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002841 261.0
PYH2_k127_6899211_21 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
PYH2_k127_6899211_22 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003472 253.0
PYH2_k127_6899211_23 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000003797 230.0
PYH2_k127_6899211_24 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000009594 223.0
PYH2_k127_6899211_25 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000008845 208.0
PYH2_k127_6899211_26 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000002442 201.0
PYH2_k127_6899211_27 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000001736 201.0
PYH2_k127_6899211_28 ABC-type branched-chain amino acid transport K01999 - - 0.0000000000000000000000000000000000000000000000000086 186.0
PYH2_k127_6899211_29 - - - - 0.000000000000000000000000000000000000000000000001933 183.0
PYH2_k127_6899211_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 537.0
PYH2_k127_6899211_30 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000001135 176.0
PYH2_k127_6899211_31 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000001446 163.0
PYH2_k127_6899211_32 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000000000000000000001768 147.0
PYH2_k127_6899211_33 PFAM peptidase S16 lon domain protein K07157 - - 0.0000000000000000000000000000001284 135.0
PYH2_k127_6899211_34 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000001467 124.0
PYH2_k127_6899211_35 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000001293 118.0
PYH2_k127_6899211_36 Chloramphenicol phosphotransferase-like protein K18554 - - 0.00000000000000000000000004253 109.0
PYH2_k127_6899211_37 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000222 107.0
PYH2_k127_6899211_38 conserved protein, contains double-stranded beta-helix domain K00450,K06720 - 1.13.11.4,4.2.1.108 0.0000000000000000000001482 101.0
PYH2_k127_6899211_39 transmembrane transporter activity - - - 0.000000000000000000003779 95.0
PYH2_k127_6899211_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 516.0
PYH2_k127_6899211_40 PLD-like domain - - - 0.000000000000000001503 94.0
PYH2_k127_6899211_41 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000148 83.0
PYH2_k127_6899211_42 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000216 86.0
PYH2_k127_6899211_43 - - - - 0.000000000000007401 79.0
PYH2_k127_6899211_44 response regulator - - - 0.0000000000002703 84.0
PYH2_k127_6899211_45 transcriptional regulator, LuxR family - - - 0.000000000002446 81.0
PYH2_k127_6899211_46 Integrase, catalytic region - - - 0.000000000005951 72.0
PYH2_k127_6899211_47 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00001734 49.0
PYH2_k127_6899211_48 aminopeptidase N - - - 0.00004431 56.0
PYH2_k127_6899211_49 cellulase activity - - - 0.0003493 52.0
PYH2_k127_6899211_5 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 451.0
PYH2_k127_6899211_50 - - - - 0.0007542 50.0
PYH2_k127_6899211_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 428.0
PYH2_k127_6899211_7 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 414.0
PYH2_k127_6899211_8 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 395.0
PYH2_k127_6899211_9 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 385.0
PYH2_k127_6915378_0 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 574.0
PYH2_k127_6915378_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 276.0
PYH2_k127_6956976_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 448.0
PYH2_k127_6956976_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 425.0
PYH2_k127_6956976_10 - - - - 0.0006911 42.0
PYH2_k127_6956976_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 344.0
PYH2_k127_6956976_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 295.0
PYH2_k127_6956976_4 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003183 250.0
PYH2_k127_6956976_5 - - - - 0.000000000000000000000000000000000000000000000000001421 198.0
PYH2_k127_6956976_6 mRNA catabolic process K06950 - - 0.000000000000000000000000000000000000000000327 171.0
PYH2_k127_6956976_7 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000219 98.0
PYH2_k127_6956976_8 Cell Wall Hydrolase - - - 0.000000000001043 79.0
PYH2_k127_6956976_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000001424 68.0
PYH2_k127_6994569_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 625.0
PYH2_k127_6994569_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000002043 87.0
PYH2_k127_7009492_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 4.69e-207 654.0
PYH2_k127_7009492_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 582.0
PYH2_k127_7009492_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000009488 200.0
PYH2_k127_7009492_11 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000002531 179.0
PYH2_k127_7009492_12 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000001888 172.0
PYH2_k127_7009492_13 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000638 118.0
PYH2_k127_7009492_14 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000001401 115.0
PYH2_k127_7009492_2 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 576.0
PYH2_k127_7009492_3 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 517.0
PYH2_k127_7009492_4 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 481.0
PYH2_k127_7009492_5 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 415.0
PYH2_k127_7009492_6 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 355.0
PYH2_k127_7009492_7 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 331.0
PYH2_k127_7009492_8 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 300.0
PYH2_k127_7009492_9 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000253 250.0
PYH2_k127_7017922_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
PYH2_k127_7017922_1 Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000009079 256.0
PYH2_k127_7017922_2 histidine kinase A domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001076 235.0
PYH2_k127_7017922_3 Domain of unknown function (DUF4111) - - - 0.000000000000000000000000000000000000000000001312 177.0
PYH2_k127_7017922_4 chromate transport K07240 - - 0.0000000000000000000000000000000000000001103 156.0
PYH2_k127_7017922_5 chromate transport K07240 - - 0.00000000000000000000000000002591 124.0
PYH2_k127_7021088_0 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 387.0
PYH2_k127_7021088_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 364.0
PYH2_k127_7021088_10 peroxiredoxin activity - - - 0.0000000000000000000000000001558 122.0
PYH2_k127_7021088_11 - - - - 0.0000000000000000000000009389 114.0
PYH2_k127_7021088_12 - - - - 0.00000000000000000000001185 104.0
PYH2_k127_7021088_13 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000007368 92.0
PYH2_k127_7021088_14 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000004164 80.0
PYH2_k127_7021088_16 - - - - 0.0000000002832 64.0
PYH2_k127_7021088_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 328.0
PYH2_k127_7021088_3 DNA photolyase domain protein K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006573 286.0
PYH2_k127_7021088_4 Alternative locus ID - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003947 259.0
PYH2_k127_7021088_5 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000007733 199.0
PYH2_k127_7021088_6 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000004585 176.0
PYH2_k127_7021088_7 nitric oxide dioxygenase activity K21405 - - 0.00000000000000000000000000000000000000001261 162.0
PYH2_k127_7021088_8 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000004682 154.0
PYH2_k127_7021088_9 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000001344 126.0
PYH2_k127_7035495_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.833e-258 820.0
PYH2_k127_7035495_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 471.0
PYH2_k127_7035495_10 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000326 240.0
PYH2_k127_7035495_11 - - - - 0.00000000000000000000000000000000000000000000000000000002768 219.0
PYH2_k127_7035495_12 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000003935 196.0
PYH2_k127_7035495_13 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000219 194.0
PYH2_k127_7035495_14 Protein of unknown function (DUF2938) - - - 0.00000000000000000000000000000000000000000000000006193 182.0
PYH2_k127_7035495_15 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000001035 192.0
PYH2_k127_7035495_16 methyltransferase K05928 - 2.1.1.95 0.0000000000000000000000000000000000000000000004738 176.0
PYH2_k127_7035495_17 DinB family - - - 0.0000000000000000000000000000000656 132.0
PYH2_k127_7035495_18 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000009528 134.0
PYH2_k127_7035495_19 ThiS family K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000007735 104.0
PYH2_k127_7035495_2 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 403.0
PYH2_k127_7035495_20 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000000000005862 100.0
PYH2_k127_7035495_21 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000003424 104.0
PYH2_k127_7035495_22 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000007067 111.0
PYH2_k127_7035495_23 Bacterial extracellular solute-binding protein - - - 0.000000000000000004435 98.0
PYH2_k127_7035495_24 TipAS antibiotic-recognition domain - - - 0.000000000000001657 81.0
PYH2_k127_7035495_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000005722 79.0
PYH2_k127_7035495_26 PFAM Integrase core domain - - - 0.0000000002982 69.0
PYH2_k127_7035495_27 transposition K07497 - - 0.000000001141 67.0
PYH2_k127_7035495_28 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000008829 64.0
PYH2_k127_7035495_3 PFAM O-antigen polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 398.0
PYH2_k127_7035495_30 - - - - 0.00001814 57.0
PYH2_k127_7035495_31 radical SAM domain protein K06139 - - 0.0001222 46.0
PYH2_k127_7035495_32 radical SAM domain protein - - - 0.0001356 48.0
PYH2_k127_7035495_33 beta-glucosidase activity - - - 0.0004054 48.0
PYH2_k127_7035495_34 PFAM glycoside hydrolase, family 10 - - - 0.0008628 49.0
PYH2_k127_7035495_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
PYH2_k127_7035495_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 335.0
PYH2_k127_7035495_6 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 319.0
PYH2_k127_7035495_7 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002551 281.0
PYH2_k127_7035495_8 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001954 265.0
PYH2_k127_7035495_9 Monogalactosyldiacylglycerol synthase 2 K03715 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006664,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0009267,GO:0009507,GO:0009526,GO:0009527,GO:0009536,GO:0009605,GO:0009707,GO:0009941,GO:0009987,GO:0009991,GO:0016020,GO:0016036,GO:0016740,GO:0016757,GO:0016758,GO:0019374,GO:0019752,GO:0019867,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0031967,GO:0031968,GO:0031969,GO:0031975,GO:0032787,GO:0033554,GO:0035250,GO:0042170,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0098588,GO:0098805,GO:1901135,GO:1903509 2.4.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000115 256.0
PYH2_k127_7043460_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 588.0
PYH2_k127_7043460_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 508.0
PYH2_k127_7043460_2 Ethanolamine utilization protein EutJ K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 355.0
PYH2_k127_7043460_3 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 328.0
PYH2_k127_7043460_4 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001582 263.0
PYH2_k127_7043460_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004068 263.0
PYH2_k127_7043460_6 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000008731 225.0
PYH2_k127_7043460_7 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000002445 177.0
PYH2_k127_7043460_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000002866 109.0
PYH2_k127_7063779_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1130.0
PYH2_k127_7063779_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 368.0
PYH2_k127_7063779_2 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 335.0
PYH2_k127_7063779_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 311.0
PYH2_k127_7063779_4 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004156 277.0
PYH2_k127_7063779_5 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000008804 226.0
PYH2_k127_7063779_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000003446 171.0
PYH2_k127_7063779_7 Hemerythrin HHE cation binding domain - - - 0.0000000001 70.0
PYH2_k127_7063779_8 Belongs to the Nudix hydrolase family K18445 - 3.6.1.61 0.000000001982 64.0
PYH2_k127_7063779_9 - - - - 0.00000342 54.0
PYH2_k127_7070472_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 369.0
PYH2_k127_7070472_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000001352 130.0
PYH2_k127_7070472_2 Transposase - - - 0.00000000000000004507 85.0
PYH2_k127_7070472_3 Diguanylate cyclase - - - 0.00003355 52.0
PYH2_k127_7086890_0 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 492.0
PYH2_k127_7086890_1 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 309.0
PYH2_k127_7086890_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
PYH2_k127_7086890_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000003749 233.0
PYH2_k127_7086890_4 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000007829 181.0
PYH2_k127_7086890_5 filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000008 188.0
PYH2_k127_7086890_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000003628 83.0
PYH2_k127_7118919_0 extracellular solute-binding protein, family 1 K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 455.0
PYH2_k127_7118919_1 thiamine transport K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 364.0
PYH2_k127_7118919_2 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000003432 192.0
PYH2_k127_7118919_3 - - - - 0.000000000001005 72.0
PYH2_k127_7167289_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001439 275.0
PYH2_k127_7167289_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003793 266.0
PYH2_k127_7181188_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.179e-278 869.0
PYH2_k127_7181188_1 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000006811 246.0
PYH2_k127_7181188_2 [2Fe-2S] binding domain K03518,K16879 - 1.2.5.3,1.3.99.8 0.00000000000000000000000000000000000000000000007997 173.0
PYH2_k127_7181188_3 - - - - 0.00000000000000007098 92.0
PYH2_k127_7190797_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 605.0
PYH2_k127_7190797_1 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 367.0
PYH2_k127_7190797_10 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000003892 125.0
PYH2_k127_7190797_11 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000002723 102.0
PYH2_k127_7190797_12 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000004737 106.0
PYH2_k127_7190797_13 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000002137 82.0
PYH2_k127_7190797_14 PFAM O-Antigen K18814 - - 0.0000000000002449 79.0
PYH2_k127_7190797_15 lysyltransferase activity K07027 - - 0.00000000005874 74.0
PYH2_k127_7190797_2 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002916 269.0
PYH2_k127_7190797_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 259.0
PYH2_k127_7190797_4 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000398 254.0
PYH2_k127_7190797_5 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000003368 244.0
PYH2_k127_7190797_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000386 237.0
PYH2_k127_7190797_7 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000434 224.0
PYH2_k127_7190797_8 competence protein - - - 0.000000000000000000000000000000000000000000000021 178.0
PYH2_k127_7190797_9 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000392 136.0
PYH2_k127_7203358_0 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
PYH2_k127_7203358_1 PFAM ABC transporter related K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000006658 216.0
PYH2_k127_7203358_2 ABC transporter - - - 0.000000000000000000000000000002805 122.0
PYH2_k127_7216440_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 533.0
PYH2_k127_7216440_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 504.0
PYH2_k127_7216440_10 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.000000000000000000000000000000000000000000000000000000000000000004446 233.0
PYH2_k127_7216440_11 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000005168 198.0
PYH2_k127_7216440_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 456.0
PYH2_k127_7216440_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 443.0
PYH2_k127_7216440_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
PYH2_k127_7216440_5 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 351.0
PYH2_k127_7216440_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02407,K02492,K10714,K15671 GO:0005575,GO:0005623,GO:0008150,GO:0009288,GO:0040007,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 314.0
PYH2_k127_7216440_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 295.0
PYH2_k127_7216440_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008066 284.0
PYH2_k127_7216440_9 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000167 253.0
PYH2_k127_7249506_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 336.0
PYH2_k127_7249506_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 278.0
PYH2_k127_7249506_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000001443 203.0
PYH2_k127_7266512_0 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 577.0
PYH2_k127_7266512_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 467.0
PYH2_k127_7266512_2 NMT1-like family - - - 0.000000000000000000000000000000000000000001532 169.0
PYH2_k127_7266512_3 Histidine phosphatase superfamily (branch 1) K01834 - 5.4.2.11 0.0000000000000000000000000000000000000001175 159.0
PYH2_k127_7266512_5 NMT1-like family - - - 0.00000000000000000000000000000001873 139.0
PYH2_k127_7266512_6 amine dehydrogenase activity - - - 0.000000000000009564 86.0
PYH2_k127_7266512_7 PFAM regulatory protein LuxR - - - 0.0000006073 56.0
PYH2_k127_7266512_8 - - - - 0.0001508 50.0
PYH2_k127_7266512_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0009234 48.0
PYH2_k127_7266962_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 509.0
PYH2_k127_7266962_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 288.0
PYH2_k127_7266962_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001496 256.0
PYH2_k127_7266962_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000004908 245.0
PYH2_k127_7266962_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000000000000000000000000004065 150.0
PYH2_k127_7278572_0 amine dehydrogenase activity K08282,K08884 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000001062 94.0
PYH2_k127_7278572_1 PFAM purine or other phosphorylase family 1 - - - 0.000000000001367 74.0
PYH2_k127_7278572_2 TPR repeat - - - 0.000000000007073 77.0
PYH2_k127_7320244_0 Lactonase, 7-bladed beta-propeller - - - 7.262e-263 833.0
PYH2_k127_7320244_1 intracellular signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 528.0
PYH2_k127_7320244_10 PFAM nucleic acid binding, OB-fold, tRNA K01174 - 3.1.31.1 0.00000000000000002447 89.0
PYH2_k127_7320244_11 - - - - 0.0009007 49.0
PYH2_k127_7320244_2 DNA packaging K06909 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 454.0
PYH2_k127_7320244_3 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
PYH2_k127_7320244_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
PYH2_k127_7320244_5 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000001446 181.0
PYH2_k127_7320244_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000000002095 184.0
PYH2_k127_7320244_7 - - - - 0.000000000000000000000000000002587 123.0
PYH2_k127_7320244_8 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000004065 117.0
PYH2_k127_7320244_9 SCP-2 sterol transfer family - - - 0.0000000000000000000000001105 118.0
PYH2_k127_7331877_0 sh3 domain protein - - - 0.000006393 59.0
PYH2_k127_7348637_0 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 473.0
PYH2_k127_7348637_1 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 307.0
PYH2_k127_7348637_2 Protein of unknown function (DUF1722) K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009843 267.0
PYH2_k127_7348637_3 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000004867 105.0
PYH2_k127_7357206_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 317.0
PYH2_k127_7357206_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000004646 115.0
PYH2_k127_7372030_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 522.0
PYH2_k127_7406088_0 Probable transposase K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 297.0
PYH2_k127_7406088_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000001366 210.0
PYH2_k127_7406088_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000001017 166.0
PYH2_k127_7406088_3 Methyltransferase domain K06987 - - 0.0000000000000000000000000000000002137 139.0
PYH2_k127_7406088_4 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000003708 119.0
PYH2_k127_7406088_5 - - - - 0.0001746 54.0
PYH2_k127_7407112_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 595.0
PYH2_k127_7407112_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 458.0
PYH2_k127_7407112_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 373.0
PYH2_k127_7407112_4 PFAM Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000001621 195.0
PYH2_k127_7407112_5 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000006862 160.0
PYH2_k127_7407112_6 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000001347 128.0
PYH2_k127_7407112_7 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000319 120.0
PYH2_k127_7407112_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000001151 108.0
PYH2_k127_7407112_9 Domain of unknown function (DUF4870) - - - 0.0000006494 56.0
PYH2_k127_7458064_0 spore germination - - - 0.000000000000000000000000000000000000000538 154.0
PYH2_k127_7470703_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 454.0
PYH2_k127_7470703_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 349.0
PYH2_k127_7470703_10 4fe-4S ferredoxin, iron-sulfur binding domain protein K18930 - - 0.00000000000000000002381 104.0
PYH2_k127_7470703_12 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.00000000000002013 76.0
PYH2_k127_7470703_13 Tfp pilus assembly protein FimV - - - 0.000023 57.0
PYH2_k127_7470703_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 309.0
PYH2_k127_7470703_3 Nickel ABC transporter permease K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 297.0
PYH2_k127_7470703_4 Similarity to COG0437 Fe-S-cluster-containing hydrogenase components 1(Evalue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 289.0
PYH2_k127_7470703_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000001026 226.0
PYH2_k127_7470703_6 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001879 217.0
PYH2_k127_7470703_7 Nitrate reductase delta subunit K03533 - - 0.00000000000000000000000000000000002956 139.0
PYH2_k127_7470703_8 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000228 134.0
PYH2_k127_7470703_9 belongs to the sigma-70 factor family, ECF subfamily - - - 0.0000000000000000000000000001229 125.0
PYH2_k127_747889_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 522.0
PYH2_k127_747889_1 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 412.0
PYH2_k127_747889_2 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 376.0
PYH2_k127_747889_3 Major facilitator Superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 364.0
PYH2_k127_747889_4 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 351.0
PYH2_k127_747889_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
PYH2_k127_7495919_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 486.0
PYH2_k127_7495919_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 340.0
PYH2_k127_7495919_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000009917 141.0
PYH2_k127_7495919_3 Protein of unknown function (DUF1343) - - - 0.00000000000000718 76.0
PYH2_k127_7514722_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 4.752e-205 648.0
PYH2_k127_7514722_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 610.0
PYH2_k127_7514722_10 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000009103 85.0
PYH2_k127_7514722_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000002698 65.0
PYH2_k127_7514722_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K00216 - 1.1.1.100,1.3.1.28 0.00000000424 64.0
PYH2_k127_7514722_13 2-haloalkanoic acid dehalogenase K01560,K07025 - 3.8.1.2 0.0000002 52.0
PYH2_k127_7514722_14 acyl-CoA transferases carnitine dehydratase - - - 0.000006934 53.0
PYH2_k127_7514722_15 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00001242 49.0
PYH2_k127_7514722_16 enoyl-CoA hydratase K15866 - 5.3.3.18 0.0004874 46.0
PYH2_k127_7514722_17 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000842 46.0
PYH2_k127_7514722_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 458.0
PYH2_k127_7514722_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
PYH2_k127_7514722_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 391.0
PYH2_k127_7514722_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003446 219.0
PYH2_k127_7514722_6 Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000001378 188.0
PYH2_k127_7514722_7 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000004492 138.0
PYH2_k127_7514722_8 KR domain K00059 - 1.1.1.100 0.00000000000000000000002744 102.0
PYH2_k127_7514722_9 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000022 89.0
PYH2_k127_7519930_0 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 620.0
PYH2_k127_7519930_1 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 610.0
PYH2_k127_7519930_10 Protein of unknown function (DUF971) K03593 - - 0.00000000000000004452 85.0
PYH2_k127_7519930_11 - - - - 0.0000000000003238 79.0
PYH2_k127_7519930_13 PFAM Pyridoxamine 5'-phosphate - - - 0.000001477 56.0
PYH2_k127_7519930_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 413.0
PYH2_k127_7519930_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 286.0
PYH2_k127_7519930_4 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001659 256.0
PYH2_k127_7519930_5 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000576 256.0
PYH2_k127_7519930_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002071 246.0
PYH2_k127_7519930_7 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000000000000000000000000000000000000000002419 172.0
PYH2_k127_7519930_8 methyltransferase - - - 0.000000000000000000000000000000002932 135.0
PYH2_k127_7531280_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 536.0
PYH2_k127_7531280_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 306.0
PYH2_k127_7531280_2 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 307.0
PYH2_k127_7531280_3 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 306.0
PYH2_k127_7531280_4 Permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 300.0
PYH2_k127_7531280_5 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000006075 204.0
PYH2_k127_7531280_6 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000003134 136.0
PYH2_k127_7531280_7 GNAT acetyltransferase - - - 0.000004306 55.0
PYH2_k127_7557525_0 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 458.0
PYH2_k127_7557525_1 Pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 301.0
PYH2_k127_7557525_11 - - - - 0.00000000000000000000000000000001504 129.0
PYH2_k127_7557525_12 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000001499 91.0
PYH2_k127_7557525_13 Pfam:DUF385 - - - 0.00000004438 62.0
PYH2_k127_7557525_14 - - - - 0.0002886 50.0
PYH2_k127_7557525_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000003012 233.0
PYH2_k127_7557525_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000001147 195.0
PYH2_k127_7557525_4 transcription activator, effector binding - - - 0.0000000000000000000000000000000000000000000000000003061 191.0
PYH2_k127_7557525_5 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000007177 178.0
PYH2_k127_7557525_6 PFAM FAD dependent oxidoreductase K09835 - 5.2.1.13 0.00000000000000000000000000000000000000000000004982 177.0
PYH2_k127_7557525_7 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000000000000000000000000003863 171.0
PYH2_k127_7557525_8 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000002025 170.0
PYH2_k127_7557525_9 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000004466 141.0
PYH2_k127_7558922_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 535.0
PYH2_k127_7558922_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000001939 176.0
PYH2_k127_7558922_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000007411 49.0
PYH2_k127_7560010_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 524.0
PYH2_k127_7560010_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001241 289.0
PYH2_k127_7560010_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000005063 169.0
PYH2_k127_7560010_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000003601 99.0
PYH2_k127_7560010_4 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K01802,K07533 - 5.2.1.8 0.00000000000000000000117 108.0
PYH2_k127_7560010_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000001008 91.0
PYH2_k127_7560010_6 Peptidase family M23 - - - 0.000000000000003283 90.0
PYH2_k127_7560010_7 RHS Repeat - - - 0.000000002364 64.0
PYH2_k127_7584740_0 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 418.0
PYH2_k127_7584740_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 407.0
PYH2_k127_7584740_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 402.0
PYH2_k127_7584740_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 323.0
PYH2_k127_7584740_4 3-hexulose-6-phosphate synthase K08093 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000213 254.0
PYH2_k127_7584740_5 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000005618 231.0
PYH2_k127_7584740_6 - - - - 0.000000000000000000000002253 115.0
PYH2_k127_7584740_7 Protein of unknown function (DUF3887) K06889 - - 0.000000000000000001655 91.0
PYH2_k127_7584740_8 response to heat - - - 0.000000000006502 76.0
PYH2_k127_7589562_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 359.0
PYH2_k127_7589562_1 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 292.0
PYH2_k127_7589562_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000008534 211.0
PYH2_k127_7589562_3 glycosyl transferase group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000005902 192.0
PYH2_k127_7589562_4 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000004603 178.0
PYH2_k127_7589562_5 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000008394 176.0
PYH2_k127_7595256_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007083 278.0
PYH2_k127_7595256_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000005308 235.0
PYH2_k127_7638302_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 466.0
PYH2_k127_7638302_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 481.0
PYH2_k127_7638302_10 Hydrolase, NUDIX family K03574,K17816 - 3.6.1.55,3.6.1.56 0.000000000000000000000000000000000000000000001968 170.0
PYH2_k127_7638302_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000191 135.0
PYH2_k127_7638302_12 GtrA-like protein - - - 0.00000000000000000000000003542 113.0
PYH2_k127_7638302_13 - - - - 0.0000000000000002594 81.0
PYH2_k127_7638302_14 Putative esterase - - - 0.0000000000001549 70.0
PYH2_k127_7638302_15 Putative esterase - - - 0.000000000001636 70.0
PYH2_k127_7638302_16 shape-determining protein MreD K03571 - - 0.00000004521 61.0
PYH2_k127_7638302_17 phosphatidylinositol metabolic process - - - 0.00006727 56.0
PYH2_k127_7638302_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 454.0
PYH2_k127_7638302_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 314.0
PYH2_k127_7638302_4 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 280.0
PYH2_k127_7638302_5 -O-antigen K05350,K21000 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005774 303.0
PYH2_k127_7638302_6 pathogenesis K21471,K21687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008311 283.0
PYH2_k127_7638302_7 PFAM O-antigen polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001567 246.0
PYH2_k127_7638302_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000001922 207.0
PYH2_k127_7638302_9 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000003848 181.0
PYH2_k127_7661891_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 433.0
PYH2_k127_7661891_1 N-terminal 7TM region of histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 445.0
PYH2_k127_7661891_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 423.0
PYH2_k127_7661891_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 319.0
PYH2_k127_7661891_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 299.0
PYH2_k127_7661891_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
PYH2_k127_7661891_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000009255 235.0
PYH2_k127_7661891_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000001965 219.0
PYH2_k127_7661891_8 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000006767 214.0
PYH2_k127_7661891_9 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000001296 160.0
PYH2_k127_7661925_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 375.0
PYH2_k127_7661925_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000002636 216.0
PYH2_k127_7691147_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.917e-234 746.0
PYH2_k127_7691147_1 Pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 1.7e-205 659.0
PYH2_k127_7691147_10 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000000000000001411 159.0
PYH2_k127_7691147_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001085 148.0
PYH2_k127_7691147_12 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000497 125.0
PYH2_k127_7691147_13 Transcriptional regulator K03724 - - 0.000000000000000004884 90.0
PYH2_k127_7691147_14 Peptidoglycan-binding lysin domain - - - 0.000000000000001327 87.0
PYH2_k127_7691147_15 Peptidase family M23 - - - 0.000000000001031 79.0
PYH2_k127_7691147_16 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000009657 66.0
PYH2_k127_7691147_18 adenosylcobinamide amidohydrolase - - - 0.0000005268 55.0
PYH2_k127_7691147_2 intracellular signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 537.0
PYH2_k127_7691147_20 NUDIX domain K03574 - 3.6.1.55 0.0002242 50.0
PYH2_k127_7691147_3 Streptomycin adenylyltransferase K05593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
PYH2_k127_7691147_4 4Fe-4S binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 306.0
PYH2_k127_7691147_5 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 278.0
PYH2_k127_7691147_6 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002428 266.0
PYH2_k127_7691147_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004273 229.0
PYH2_k127_7691147_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000002389 196.0
PYH2_k127_7691147_9 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000001667 185.0
PYH2_k127_7724049_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.248e-253 797.0
PYH2_k127_7724049_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 5.861e-231 723.0
PYH2_k127_7724049_10 spore germination K03605 - - 0.00000000000000000002665 98.0
PYH2_k127_7724049_11 Histidine kinase - - - 0.000000000004861 68.0
PYH2_k127_7724049_2 Cysteine-rich domain K21834 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 508.0
PYH2_k127_7724049_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 383.0
PYH2_k127_7724049_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 382.0
PYH2_k127_7724049_5 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008641 271.0
PYH2_k127_7724049_6 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000002477 220.0
PYH2_k127_7724049_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000004761 210.0
PYH2_k127_7724049_8 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000005277 194.0
PYH2_k127_7724049_9 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000004666 187.0
PYH2_k127_7726161_0 Transcriptional regulator - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 496.0
PYH2_k127_7726161_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 324.0
PYH2_k127_7726161_2 Protein of unknown function (DUF4242) - - - 0.0007843 43.0
PYH2_k127_7735457_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 499.0
PYH2_k127_7735457_1 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 446.0
PYH2_k127_7735457_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 396.0
PYH2_k127_7735457_3 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 360.0
PYH2_k127_7747347_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 571.0
PYH2_k127_7747347_1 PFAM aminotransferase class V K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 424.0
PYH2_k127_7747347_2 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
PYH2_k127_7747347_3 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000001622 250.0
PYH2_k127_7747347_4 Peptidase M50 - - - 0.00000000000000000000000000000000000002271 152.0
PYH2_k127_7747347_5 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.0000000000000000000000000000000003493 137.0
PYH2_k127_7747347_6 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000004045 115.0
PYH2_k127_7747347_7 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000002914 86.0
PYH2_k127_7769453_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.526e-241 756.0
PYH2_k127_7769453_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 5.544e-200 630.0
PYH2_k127_7769453_2 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 519.0
PYH2_k127_7769453_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 424.0
PYH2_k127_7769453_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000158 239.0
PYH2_k127_7769453_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000004147 173.0
PYH2_k127_7769453_6 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000002337 131.0
PYH2_k127_7769453_7 NACHT domain K12132 - 2.7.11.1 0.00000000000000127 80.0
PYH2_k127_7769453_8 Parallel beta-helix repeats - - - 0.00000000001698 77.0
PYH2_k127_7769453_9 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.00004144 52.0
PYH2_k127_7806686_0 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 501.0
PYH2_k127_7806686_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 439.0
PYH2_k127_7806686_2 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 420.0
PYH2_k127_7806686_3 Amb_all K01728 - 4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 416.0
PYH2_k127_7806686_4 PFAM Bacterial extracellular solute-binding K17318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 408.0
PYH2_k127_7806686_5 pectinesterase activity K01051,K10297 GO:0005575,GO:0005576 3.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 347.0
PYH2_k127_7806686_6 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 340.0
PYH2_k127_7806686_7 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 336.0
PYH2_k127_7806686_8 Aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 296.0
PYH2_k127_7806686_9 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000686 281.0
PYH2_k127_7816380_0 helix_turn_helix, Lux Regulon K03556 - - 6.092e-197 645.0
PYH2_k127_7816380_1 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 391.0
PYH2_k127_7816380_2 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000009821 162.0
PYH2_k127_7816380_3 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000002782 83.0
PYH2_k127_7816380_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000562 77.0
PYH2_k127_7816380_5 - - - - 0.000001239 52.0
PYH2_k127_7830023_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000004418 254.0
PYH2_k127_7830023_1 PFAM regulatory protein LuxR - - - 0.000000003859 69.0
PYH2_k127_7830023_2 transposition, DNA-mediated - - - 0.00001126 49.0
PYH2_k127_7842611_0 uridine kinase K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 606.0
PYH2_k127_7842611_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 284.0
PYH2_k127_7842611_10 antisigma factor binding K04749 - - 0.00004167 49.0
PYH2_k127_7842611_2 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002268 258.0
PYH2_k127_7842611_3 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000006376 236.0
PYH2_k127_7842611_4 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.00000000000000000000000000000000000000000000000000000000000001083 218.0
PYH2_k127_7842611_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000002023 215.0
PYH2_k127_7842611_6 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000006926 191.0
PYH2_k127_7842611_7 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000897 155.0
PYH2_k127_7842611_8 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000001761 95.0
PYH2_k127_7842611_9 Transcriptional activator domain - - - 0.00000000001282 70.0
PYH2_k127_7855241_3 PFAM Transposase, IS204 IS1001 IS1096 IS1165 - - - 0.00001303 50.0
PYH2_k127_7877882_0 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 470.0
PYH2_k127_7877882_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 434.0
PYH2_k127_7877882_2 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 318.0
PYH2_k127_7877882_3 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000005816 206.0
PYH2_k127_7877882_4 HIT domain - - - 0.0000000000000000000000000000000000000000000000000000004627 197.0
PYH2_k127_7877882_5 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.0000000000000000000000000000000000001373 148.0
PYH2_k127_7877882_6 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.00000000000000000000000000000000007861 137.0
PYH2_k127_7877882_7 Yqey-like protein K09117 - - 0.0000000000000000000000000000008066 128.0
PYH2_k127_7877882_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000008162 114.0
PYH2_k127_7887982_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.393e-208 666.0
PYH2_k127_7887982_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 599.0
PYH2_k127_7887982_10 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002167 279.0
PYH2_k127_7887982_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 533.0
PYH2_k127_7887982_3 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 430.0
PYH2_k127_7887982_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 376.0
PYH2_k127_7887982_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 370.0
PYH2_k127_7887982_6 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
PYH2_k127_7887982_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 312.0
PYH2_k127_7887982_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 318.0
PYH2_k127_7887982_9 PFAM purine or other phosphorylase family 1 K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
PYH2_k127_7899731_0 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000009221 230.0
PYH2_k127_7899731_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000003904 182.0
PYH2_k127_7904040_0 helicase activity K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 445.0
PYH2_k127_7904040_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 318.0
PYH2_k127_7904040_2 3'-5' exonuclease activity K03546,K03547 - - 0.000000000000000000000000000000000000000000000000000000000000004421 231.0
PYH2_k127_7904040_3 Glyoxalase-like domain K07032 - - 0.00000000000000000000000000000000000000000000000000000000002607 208.0
PYH2_k127_7904040_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000892 200.0
PYH2_k127_7904040_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000009582 179.0
PYH2_k127_7904040_6 - - - - 0.000000000000000000000000000000000000000000001846 170.0
PYH2_k127_7904040_7 - - - - 0.0000000000000000000000000000015 126.0
PYH2_k127_7904040_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000001584 109.0
PYH2_k127_7904040_9 Acetyltransferase (GNAT) family - - - 0.000001419 58.0
PYH2_k127_7916142_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 406.0
PYH2_k127_7916142_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 336.0
PYH2_k127_7916142_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 295.0
PYH2_k127_7916142_3 proline dipeptidase activity K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000003743 222.0
PYH2_k127_795323_0 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 364.0
PYH2_k127_795323_1 Cell cycle protein K03588,K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008165 283.0
PYH2_k127_795323_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000002543 158.0
PYH2_k127_795323_3 Peptidase_C39 like family - - - 0.000000000000000000003037 104.0
PYH2_k127_795323_4 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000003489 76.0
PYH2_k127_795323_5 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000009154 69.0
PYH2_k127_7967529_0 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000001229 113.0
PYH2_k127_7967529_1 Belongs to the peptidase S8 family - - - 0.0000000000131 78.0
PYH2_k127_7967529_2 Carbohydrate binding module (family 6) - - - 0.00000000003591 69.0
PYH2_k127_797919_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 527.0
PYH2_k127_797919_1 PFAM D-galactarate dehydratase Altronate hydrolase K16846 - 4.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 515.0
PYH2_k127_797919_10 Protein of unknown function (DUF692) - - - 0.0000000000000008517 81.0
PYH2_k127_797919_11 membrane K08978,K12962 - - 0.000000000000001561 82.0
PYH2_k127_797919_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000007249 67.0
PYH2_k127_797919_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 376.0
PYH2_k127_797919_3 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 364.0
PYH2_k127_797919_4 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
PYH2_k127_797919_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007083 278.0
PYH2_k127_797919_6 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000003222 176.0
PYH2_k127_797919_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000001524 143.0
PYH2_k127_797919_8 sulfolactate sulfo-lyase activity K01685,K16845 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7,4.4.1.24 0.000000000000000000000000121 109.0
PYH2_k127_797919_9 Protein of unknown function (DUF692) - - - 0.0000000000000000000006033 102.0
PYH2_k127_7986729_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.757e-220 693.0
PYH2_k127_7986729_1 transcriptional regulator K07736 - - 0.000009139 55.0
PYH2_k127_7992215_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 1.753e-307 962.0
PYH2_k127_7992215_1 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 7.193e-219 687.0
PYH2_k127_7992215_10 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000006379 208.0
PYH2_k127_7992215_11 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000001078 164.0
PYH2_k127_7992215_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 448.0
PYH2_k127_7992215_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 425.0
PYH2_k127_7992215_4 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 349.0
PYH2_k127_7992215_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 295.0
PYH2_k127_7992215_6 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 288.0
PYH2_k127_7992215_7 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003359 295.0
PYH2_k127_7992215_8 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005715 267.0
PYH2_k127_7992215_9 phosphatase activity K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000003865 268.0
PYH2_k127_7995015_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 612.0
PYH2_k127_7995015_1 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 422.0
PYH2_k127_7995015_10 PFAM Fibronectin type III domain - - - 0.0004192 53.0
PYH2_k127_7995015_2 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 395.0
PYH2_k127_7995015_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 388.0
PYH2_k127_7995015_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 381.0
PYH2_k127_7995015_5 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007134 283.0
PYH2_k127_7995015_6 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000001141 223.0
PYH2_k127_7995015_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000026 162.0
PYH2_k127_7995015_8 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000001344 89.0
PYH2_k127_7995015_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000001127 74.0
PYH2_k127_8000304_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 603.0
PYH2_k127_8000304_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 532.0
PYH2_k127_8000304_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 378.0
PYH2_k127_8000304_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001555 219.0
PYH2_k127_8000304_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000003432 164.0
PYH2_k127_8000304_5 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000004177 153.0
PYH2_k127_8000304_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000005578 144.0
PYH2_k127_8000304_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000004528 134.0
PYH2_k127_8000304_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000001145 123.0
PYH2_k127_802486_0 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 306.0
PYH2_k127_802486_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 283.0
PYH2_k127_802486_2 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000004812 221.0
PYH2_k127_802486_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000001118 190.0
PYH2_k127_802486_4 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000001592 182.0
PYH2_k127_802486_5 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000001977 163.0
PYH2_k127_802486_6 - - - - 0.00000000000000000000000000000000000687 140.0
PYH2_k127_802486_7 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000001566 104.0
PYH2_k127_8026278_0 helix_turn_helix, Lux Regulon K03556 - - 3.169e-211 687.0
PYH2_k127_8026278_1 CAAX protease self-immunity K07052 - - 0.00001434 48.0
PYH2_k127_8078758_0 fructose-bisphosphate aldolase activity K01622 - 3.1.3.11,4.1.2.13 3.309e-197 620.0
PYH2_k127_8078758_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 341.0
PYH2_k127_8078758_10 uncharacterised conserved protein UCP017998 - - - 0.00000008962 62.0
PYH2_k127_8078758_11 Putative zinc-finger - - - 0.0005137 51.0
PYH2_k127_8078758_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000005719 252.0
PYH2_k127_8078758_3 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000008438 201.0
PYH2_k127_8078758_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000001149 189.0
PYH2_k127_8078758_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000009767 122.0
PYH2_k127_8078758_6 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000000000000001953 108.0
PYH2_k127_8078758_7 Peptidase MA superfamily - - - 0.0000000000000000000003913 108.0
PYH2_k127_8078758_9 Crp Fnr family transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000003556 67.0
PYH2_k127_8094264_0 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 330.0
PYH2_k127_8094264_1 Peptidase family C25 - - - 0.0000000000000000001192 103.0
PYH2_k127_8094264_2 Cna B domain protein - - - 0.0001577 53.0
PYH2_k127_8105657_0 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000000002918 220.0
PYH2_k127_8105657_1 filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000000004635 183.0
PYH2_k127_8105657_2 O-Antigen ligase - - - 0.0000000000000001517 94.0
PYH2_k127_8105657_3 - - - - 0.00000000002465 74.0
PYH2_k127_8105657_4 - - - - 0.000786 45.0
PYH2_k127_8133892_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 428.0
PYH2_k127_8133892_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000001925 134.0
PYH2_k127_8133892_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000004014 119.0
PYH2_k127_8133892_3 LysM domain - - - 0.000000000000004472 77.0
PYH2_k127_8136893_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 589.0
PYH2_k127_8136893_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 504.0
PYH2_k127_8136893_10 nucleotidyltransferase activity - - - 0.0000000000000000000000005388 108.0
PYH2_k127_8136893_11 nucleotidyltransferase activity - - - 0.000000000004491 70.0
PYH2_k127_8136893_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 310.0
PYH2_k127_8136893_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005551 260.0
PYH2_k127_8136893_4 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 254.0
PYH2_k127_8136893_5 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000625 243.0
PYH2_k127_8136893_6 glycosyl transferase group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000194 212.0
PYH2_k127_8136893_7 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000000000000000002006 165.0
PYH2_k127_8136893_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000002534 151.0
PYH2_k127_8136893_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000005335 123.0
PYH2_k127_8179975_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.0 1022.0
PYH2_k127_8179975_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0 1015.0
PYH2_k127_8179975_10 Cupin 2, conserved barrel domain protein - - - 0.0000000002565 67.0
PYH2_k127_8179975_11 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0000002846 61.0
PYH2_k127_8179975_12 - - - - 0.0000005753 52.0
PYH2_k127_8179975_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.088e-229 732.0
PYH2_k127_8179975_3 Sugar (and other) transporter - - - 6.448e-229 718.0
PYH2_k127_8179975_4 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 565.0
PYH2_k127_8179975_5 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 436.0
PYH2_k127_8179975_6 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 316.0
PYH2_k127_8179975_7 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 289.0
PYH2_k127_8179975_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000000000000000000000004969 188.0
PYH2_k127_8179975_9 Universal stress protein family - - - 0.00000000000000000000000000002257 122.0
PYH2_k127_8184578_0 - - - - 0.00000000000000000000000000000000000000000008376 173.0
PYH2_k127_8184578_1 O-methyltransferase activity - - - 0.0000000000000000000000000008086 123.0
PYH2_k127_8184578_2 membrane - - - 0.00000000000000000000007045 105.0
PYH2_k127_8220012_0 COG0433 Predicted ATPase - - - 0.0000000000000000000001169 98.0
PYH2_k127_8220012_1 COG0433 Predicted ATPase - - - 0.000000002436 59.0
PYH2_k127_82330_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.163e-290 915.0
PYH2_k127_82330_1 Aminotransferase K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 561.0
PYH2_k127_82330_10 Cupin domain - - - 0.000000000000000000000000000000000042 136.0
PYH2_k127_82330_11 - - - - 0.0000000000000000000000000000000002197 147.0
PYH2_k127_82330_12 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000000000147 134.0
PYH2_k127_82330_13 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000001512 126.0
PYH2_k127_82330_14 Ras-related protein K07904 - - 0.000000000000000000000000002146 123.0
PYH2_k127_82330_15 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000002105 117.0
PYH2_k127_82330_16 - - - - 0.0000000000000000000000002155 111.0
PYH2_k127_82330_17 lipolytic protein G-D-S-L family - - - 0.00000000000005541 75.0
PYH2_k127_82330_18 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000007276 64.0
PYH2_k127_82330_19 lipolytic protein G-D-S-L family - - - 0.0000000001276 67.0
PYH2_k127_82330_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 542.0
PYH2_k127_82330_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 541.0
PYH2_k127_82330_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 514.0
PYH2_k127_82330_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 307.0
PYH2_k127_82330_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
PYH2_k127_82330_7 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000003165 217.0
PYH2_k127_82330_8 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000002654 211.0
PYH2_k127_82330_9 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000007047 202.0
PYH2_k127_82620_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 364.0
PYH2_k127_82620_1 Histidine kinase - - - 0.00000000000009721 85.0
PYH2_k127_8302296_0 oxidation-reduction process - - - 7.803e-308 972.0
PYH2_k127_8302296_1 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 466.0
PYH2_k127_8302296_10 - - - - 0.0000000000000001045 81.0
PYH2_k127_8302296_11 Serine aminopeptidase, S33 - - - 0.0000000003064 61.0
PYH2_k127_8302296_12 - - - - 0.0000007411 62.0
PYH2_k127_8302296_2 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 332.0
PYH2_k127_8302296_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 312.0
PYH2_k127_8302296_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003261 261.0
PYH2_k127_8302296_5 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
PYH2_k127_8302296_6 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000169 195.0
PYH2_k127_8302296_7 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000853 185.0
PYH2_k127_8302296_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000005079 96.0
PYH2_k127_8302296_9 RNA-DNA hybrid ribonuclease activity K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000002669 90.0
PYH2_k127_8330987_0 PFAM Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 590.0
PYH2_k127_8330987_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001596 276.0
PYH2_k127_8330987_2 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000001948 146.0
PYH2_k127_8330987_3 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000002222 115.0
PYH2_k127_8330987_4 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000111 100.0
PYH2_k127_8330987_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000001557 97.0
PYH2_k127_8360849_0 M6 family metalloprotease domain protein - - - 3.006e-208 659.0
PYH2_k127_8360849_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002475 232.0
PYH2_k127_8360849_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000001537 200.0
PYH2_k127_8360849_3 - - - - 0.0000000000000000000000000000000000000000000007574 187.0
PYH2_k127_8360849_4 Endonuclease containing a URI domain K07461 - - 0.000000000000000000000000000000001503 132.0
PYH2_k127_8360849_5 Histidine kinase - - - 0.0000000000000000002815 99.0
PYH2_k127_8360849_6 - - - - 0.0000001105 59.0
PYH2_k127_8373325_0 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 515.0
PYH2_k127_8373325_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 395.0
PYH2_k127_8373325_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 365.0
PYH2_k127_8373325_3 PFAM Bacterial regulatory proteins, lacI family K02529,K03484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001477 268.0
PYH2_k127_8373325_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000255 137.0
PYH2_k127_8373325_5 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000000000000000116 116.0
PYH2_k127_8373325_6 - - - - 0.000000000000000000000007357 107.0
PYH2_k127_8373325_7 Cupin 2, conserved barrel domain protein - - - 0.0000003407 57.0
PYH2_k127_8377693_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 616.0
PYH2_k127_8377693_1 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 514.0
PYH2_k127_8377693_10 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000005003 189.0
PYH2_k127_8377693_11 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000471 172.0
PYH2_k127_8377693_12 DNA-binding transcription factor activity K03892 - - 0.000000000000008807 78.0
PYH2_k127_8377693_13 - - - - 0.0000004241 55.0
PYH2_k127_8377693_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 479.0
PYH2_k127_8377693_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 414.0
PYH2_k127_8377693_4 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 416.0
PYH2_k127_8377693_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 324.0
PYH2_k127_8377693_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001317 281.0
PYH2_k127_8377693_7 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
PYH2_k127_8377693_8 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000001206 209.0
PYH2_k127_8377693_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000304 194.0
PYH2_k127_8382715_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 481.0
PYH2_k127_8382715_1 TIGRFAM MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
PYH2_k127_8382715_2 CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000776 226.0
PYH2_k127_8422525_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 487.0
PYH2_k127_8422525_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 444.0
PYH2_k127_8422525_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000008344 168.0
PYH2_k127_8422525_3 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000000000000000000004234 160.0
PYH2_k127_8422525_4 Protein of unknown function (DUF2723) K14340 - - 0.00000000000000000000000000000003534 146.0
PYH2_k127_8422525_5 Hydrolase - - - 0.0000000000000000000000000000001059 131.0
PYH2_k127_8422525_6 MOSC domain - - - 0.000000000000000000000000000003072 125.0
PYH2_k127_8422525_7 InterPro IPR007367 - - - 0.00000000000000000000000001899 109.0
PYH2_k127_8422525_8 phosphoserine phosphatase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000006341 98.0
PYH2_k127_8422525_9 - - - - 0.000000000002665 68.0
PYH2_k127_842374_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.604e-244 773.0
PYH2_k127_842374_1 - - - - 0.000000000000000000000000000000000000000000000000000004742 199.0
PYH2_k127_8459147_0 Fibronectin-binding protein A N-terminus (FbpA) K12341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 334.0
PYH2_k127_8459147_1 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000003888 226.0
PYH2_k127_8459147_2 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000005039 213.0
PYH2_k127_8459147_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000003873 193.0
PYH2_k127_8459147_4 - - - - 0.00000000000000000000000000000000000000000000000001105 194.0
PYH2_k127_8459147_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000003104 116.0
PYH2_k127_8459147_6 Lysin motif K06194 - - 0.000000002505 69.0
PYH2_k127_8482966_0 Molydopterin dinucleotide binding domain K00123,K00336 - 1.17.1.9,1.6.5.3 1.226e-239 769.0
PYH2_k127_8482966_1 radical SAM domain protein - - - 7.529e-222 697.0
PYH2_k127_8482966_11 4Fe-4S dicluster domain - - - 0.000000001124 63.0
PYH2_k127_8482966_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0004026 45.0
PYH2_k127_8482966_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 1.389e-198 630.0
PYH2_k127_8482966_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 537.0
PYH2_k127_8482966_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 514.0
PYH2_k127_8482966_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 512.0
PYH2_k127_8482966_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 483.0
PYH2_k127_8482966_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002233 252.0
PYH2_k127_8482966_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000004609 219.0
PYH2_k127_8482966_9 ester cyclase - - - 0.000000000000000000003443 95.0
PYH2_k127_8486348_0 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 483.0
PYH2_k127_8486348_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773,K18779 - 2.4.2.29,2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 408.0
PYH2_k127_8486348_2 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
PYH2_k127_8486348_3 Potential Queuosine, Q, salvage protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008731 279.0
PYH2_k127_8486348_4 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001622 270.0
PYH2_k127_8486348_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000002204 232.0
PYH2_k127_8486348_6 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000007438 172.0
PYH2_k127_8486348_7 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000002838 123.0
PYH2_k127_8486997_0 ABC transporter, transmembrane region K06147,K18890 - - 1.498e-224 711.0
PYH2_k127_8486997_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002961 261.0
PYH2_k127_8486997_2 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000004119 175.0
PYH2_k127_8486997_3 PFAM RibD C-terminal domain K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000009904 174.0
PYH2_k127_8486997_4 Transposase IS200 like - - - 0.000000000000000000000000000000008297 135.0
PYH2_k127_8486997_5 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000001172 131.0
PYH2_k127_8486997_6 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000008722 124.0
PYH2_k127_8486997_7 lactoylglutathione lyase activity - - - 0.000000000101 66.0
PYH2_k127_8486997_8 PFAM Protein kinase domain - - - 0.0000008828 58.0
PYH2_k127_8493676_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 378.0
PYH2_k127_8493676_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005334 292.0
PYH2_k127_8493676_10 Membrane - - - 0.00000004525 66.0
PYH2_k127_8493676_12 Tetratricopeptide repeat - - - 0.000000319 63.0
PYH2_k127_8493676_13 Domain of unknown function (DUF1735) - - - 0.0000007903 62.0
PYH2_k127_8493676_14 Membrane - - - 0.000002936 60.0
PYH2_k127_8493676_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000001523 207.0
PYH2_k127_8493676_3 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000002842 166.0
PYH2_k127_8493676_4 Membrane - - - 0.00000000000000000000000000000000005664 154.0
PYH2_k127_8493676_5 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000002034 131.0
PYH2_k127_8493676_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000001437 124.0
PYH2_k127_8493676_7 GIY-YIG catalytic domain protein K07461 - - 0.000000000000000000001665 98.0
PYH2_k127_8493676_8 PFAM glycosyl transferase family 39 - - - 0.000000000008351 79.0
PYH2_k127_8493676_9 Membrane - - - 0.000000001376 64.0
PYH2_k127_8498304_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 417.0
PYH2_k127_8498304_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 349.0
PYH2_k127_8498304_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000002631 235.0
PYH2_k127_8498304_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000001718 233.0
PYH2_k127_8498304_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000002644 207.0
PYH2_k127_8498304_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000002809 169.0
PYH2_k127_8498304_6 cytidine deaminase activity K01489 GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.5.4.5 0.00000000000000000000000000000000000003554 146.0
PYH2_k127_8505002_0 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 591.0
PYH2_k127_8505002_1 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 587.0
PYH2_k127_8505002_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 479.0
PYH2_k127_8505002_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 449.0
PYH2_k127_8505002_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 441.0
PYH2_k127_8505002_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 425.0
PYH2_k127_8505002_6 PFAM NmrA family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006935 253.0
PYH2_k127_8505002_7 Oligopeptidase F - - - 0.00000000000000000000005392 99.0
PYH2_k127_8505002_8 23S rRNA-intervening sequence protein - - - 0.0000000001455 62.0
PYH2_k127_8505002_9 Protein of unknown function (DUF2877) - - - 0.00000001115 65.0
PYH2_k127_8522617_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 544.0
PYH2_k127_8522617_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 399.0
PYH2_k127_8522617_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000006099 139.0
PYH2_k127_8522617_11 - - - - 0.000000000007916 74.0
PYH2_k127_8522617_12 Iron-binding zinc finger CDGSH type K06886 - - 0.0000000001164 64.0
PYH2_k127_8522617_13 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000263 61.0
PYH2_k127_8522617_14 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000001892 62.0
PYH2_k127_8522617_15 SnoaL-like polyketide cyclase - - - 0.000001419 58.0
PYH2_k127_8522617_2 PFAM TrkA-N domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 342.0
PYH2_k127_8522617_3 PFAM sodium calcium exchanger membrane region K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 330.0
PYH2_k127_8522617_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
PYH2_k127_8522617_5 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000001241 220.0
PYH2_k127_8522617_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000002819 194.0
PYH2_k127_8522617_7 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000003285 181.0
PYH2_k127_8522617_8 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000000000000000000000000000000000000000001388 173.0
PYH2_k127_8522617_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000001063 169.0
PYH2_k127_8524547_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 563.0
PYH2_k127_8524547_1 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 395.0
PYH2_k127_8524547_2 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 357.0
PYH2_k127_8524547_3 transcriptional - - - 0.00000000000000000000000000000000000001754 155.0
PYH2_k127_8580060_0 PFAM acyl-CoA dehydrogenase domain protein - - - 2.728e-202 640.0
PYH2_k127_8580060_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 569.0
PYH2_k127_8580060_10 Thioredoxin-like - - - 0.000186 48.0
PYH2_k127_8580060_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 429.0
PYH2_k127_8580060_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 362.0
PYH2_k127_8580060_4 response regulator receiver K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004862 267.0
PYH2_k127_8580060_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001957 268.0
PYH2_k127_8580060_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000006008 138.0
PYH2_k127_8580060_7 - - - - 0.00000000000000000000000001979 111.0
PYH2_k127_8580060_8 InterPro IPR007367 - - - 0.000000000000000000000001389 106.0
PYH2_k127_8580060_9 helix_turn_helix, arabinose operon control protein - - - 0.000006464 51.0
PYH2_k127_8597397_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 587.0
PYH2_k127_8597397_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 344.0
PYH2_k127_8597397_2 - - - - 0.000000000000000000000000002753 117.0
PYH2_k127_8597397_3 - - - - 0.000000000000000000000007736 103.0
PYH2_k127_8606021_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005434 296.0
PYH2_k127_8606021_1 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000004107 168.0
PYH2_k127_8606021_2 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000003877 143.0
PYH2_k127_8606021_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000001274 119.0
PYH2_k127_8606021_4 heat shock protein binding - - - 0.0002371 51.0
PYH2_k127_8710309_0 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 414.0
PYH2_k127_8710309_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 284.0
PYH2_k127_8710309_2 Chase2 domain K01768,K01769,K07315,K18967 - 2.7.7.65,3.1.3.3,4.6.1.1,4.6.1.2 0.0000000000000000000000000000000000000000000005178 187.0
PYH2_k127_8710309_3 - - - - 0.00000000000000000000000000000001165 139.0
PYH2_k127_8710309_4 - - - - 0.00000000000000000000001114 104.0
PYH2_k127_8710309_5 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000001886 106.0
PYH2_k127_8710309_6 - - - - 0.00000000004249 72.0
PYH2_k127_8710309_7 Bacterial Ig-like domain (group 3) - - - 0.000000567 61.0
PYH2_k127_8728085_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 2.193e-221 705.0
PYH2_k127_8728085_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000005206 93.0
PYH2_k127_8728085_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000007742 54.0
PYH2_k127_8752381_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 454.0
PYH2_k127_8752381_1 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 336.0
PYH2_k127_8752381_10 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000000000008142 98.0
PYH2_k127_8752381_11 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000000005062 92.0
PYH2_k127_8752381_12 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000002026 78.0
PYH2_k127_8752381_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000009148 62.0
PYH2_k127_8752381_14 Domain of unknown function (DUF1905) - - - 0.00002161 46.0
PYH2_k127_8752381_15 Domain of unknown function (DUF1905) - - - 0.00009764 46.0
PYH2_k127_8752381_16 Domain of unknown function (DUF1905) - - - 0.0004827 44.0
PYH2_k127_8752381_2 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 291.0
PYH2_k127_8752381_3 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000002509 242.0
PYH2_k127_8752381_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000007952 218.0
PYH2_k127_8752381_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000005067 213.0
PYH2_k127_8752381_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000001462 210.0
PYH2_k127_8752381_7 - - - - 0.000000000000000000000000000000000000000000000000000733 195.0
PYH2_k127_8752381_8 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000006665 142.0
PYH2_k127_8752381_9 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000000000000000001439 138.0
PYH2_k127_8794434_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001231 286.0
PYH2_k127_8794434_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003359 275.0
PYH2_k127_8794434_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003842 237.0
PYH2_k127_8794434_3 Ca2 -binding protein (EF-Hand superfamily - - - 0.000000000000000000000000000000000000000000000000000000001339 206.0
PYH2_k127_8794434_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000001826 131.0
PYH2_k127_8795687_0 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 309.0
PYH2_k127_8795687_1 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008099 279.0
PYH2_k127_8798174_0 Transposase K07492 - - 0.00000000000000000000000000004406 120.0
PYH2_k127_8798174_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000001805 89.0
PYH2_k127_8798174_2 domain, Protein - - - 0.00000000000001192 83.0
PYH2_k127_8798174_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00001367 58.0
PYH2_k127_8802236_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 507.0
PYH2_k127_8802236_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000007338 151.0
PYH2_k127_8815638_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.619e-241 759.0
PYH2_k127_8815638_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 541.0
PYH2_k127_8815638_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 377.0
PYH2_k127_8815638_3 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000000000000002044 130.0
PYH2_k127_8815638_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000001101 120.0
PYH2_k127_8815638_5 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0004156 47.0
PYH2_k127_8830687_0 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000009593 243.0
PYH2_k127_8830687_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001921 226.0
PYH2_k127_8830687_2 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000002455 186.0
PYH2_k127_8830687_3 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000000000009978 169.0
PYH2_k127_8830687_4 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000000000000102 148.0
PYH2_k127_8830687_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000002162 111.0
PYH2_k127_8830687_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000004682 79.0
PYH2_k127_8830687_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000261 68.0
PYH2_k127_8830700_0 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 553.0
PYH2_k127_8830700_1 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 485.0
PYH2_k127_8830700_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 469.0
PYH2_k127_8830700_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 345.0
PYH2_k127_8830700_4 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004934 278.0
PYH2_k127_8830700_5 Allophanate hydrolase subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002854 237.0
PYH2_k127_8830700_6 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
PYH2_k127_8830700_7 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000001704 163.0
PYH2_k127_8830700_8 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000004915 141.0
PYH2_k127_8833779_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 354.0
PYH2_k127_8833779_1 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 310.0
PYH2_k127_8833779_10 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000004531 199.0
PYH2_k127_8833779_11 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000007375 190.0
PYH2_k127_8833779_12 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000002023 164.0
PYH2_k127_8833779_13 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000007447 164.0
PYH2_k127_8833779_14 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000002515 131.0
PYH2_k127_8833779_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000004698 119.0
PYH2_k127_8833779_16 PFAM Glycosyl transferase, group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.0000000000000000000005154 109.0
PYH2_k127_8833779_17 - K14340 - - 0.000000005513 69.0
PYH2_k127_8833779_18 Methyltransferase required for the conversion of 2- phytyl-1,4-beta-naphthoquinol to phylloquinol K03183 - 2.1.1.163,2.1.1.201 0.0000003631 61.0
PYH2_k127_8833779_19 O-Antigen ligase K18814 - - 0.00001056 58.0
PYH2_k127_8833779_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 290.0
PYH2_k127_8833779_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009191 275.0
PYH2_k127_8833779_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000296 270.0
PYH2_k127_8833779_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000156 258.0
PYH2_k127_8833779_6 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
PYH2_k127_8833779_7 FemAB family - - - 0.00000000000000000000000000000000000000000000000000000001029 212.0
PYH2_k127_8833779_8 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000004925 198.0
PYH2_k127_8833779_9 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000009148 198.0
PYH2_k127_8880511_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 556.0
PYH2_k127_8880511_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 433.0
PYH2_k127_8887217_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1312.0
PYH2_k127_8887217_1 Serine carboxypeptidase - - - 4.035e-218 686.0
PYH2_k127_8887217_2 Belongs to the UPF0441 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002942 248.0
PYH2_k127_8887217_3 - - - - 0.00000000000000000000000000000000000000000000003988 180.0
PYH2_k127_8899652_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 399.0
PYH2_k127_8899652_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 293.0
PYH2_k127_8899652_2 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001148 284.0
PYH2_k127_8899652_3 ABC transporter, ATP-binding protein K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001159 282.0
PYH2_k127_8899652_4 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002027 273.0
PYH2_k127_8917271_0 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 601.0
PYH2_k127_8917271_1 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 543.0
PYH2_k127_8917271_10 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 299.0
PYH2_k127_8917271_11 COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001794 290.0
PYH2_k127_8917271_12 Xylose isomerase-like TIM barrel K22233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002659 248.0
PYH2_k127_8917271_13 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000001859 239.0
PYH2_k127_8917271_14 domain, Protein K01729,K09942 - 4.2.2.3 0.00000000000000000000000000000000000000000000000000000000001608 224.0
PYH2_k127_8917271_15 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000001587 213.0
PYH2_k127_8917271_16 - - - - 0.00000000000000000000000000000000000000000000000001144 189.0
PYH2_k127_8917271_17 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000008134 171.0
PYH2_k127_8917271_18 protein secretion K08651 - 3.4.21.66 0.0000000000001562 77.0
PYH2_k127_8917271_19 - - - - 0.0000682 52.0
PYH2_k127_8917271_2 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 475.0
PYH2_k127_8917271_3 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 427.0
PYH2_k127_8917271_4 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 404.0
PYH2_k127_8917271_5 thiamine transport K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 394.0
PYH2_k127_8917271_6 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 326.0
PYH2_k127_8917271_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 318.0
PYH2_k127_8917271_8 Belongs to the Pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
PYH2_k127_8917271_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 301.0
PYH2_k127_8923365_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 614.0
PYH2_k127_8923365_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 547.0
PYH2_k127_8923365_10 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000002061 187.0
PYH2_k127_8923365_11 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000004978 175.0
PYH2_k127_8923365_12 - - - - 0.00000000000000001542 98.0
PYH2_k127_8923365_13 Polysaccharide biosynthesis protein - - - 0.0000000000002442 84.0
PYH2_k127_8923365_14 nucleotidyltransferase activity - - - 0.000002895 52.0
PYH2_k127_8923365_15 O-antigen polymerase K18814 - - 0.000005356 59.0
PYH2_k127_8923365_2 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 388.0
PYH2_k127_8923365_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 362.0
PYH2_k127_8923365_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 346.0
PYH2_k127_8923365_5 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 292.0
PYH2_k127_8923365_6 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 293.0
PYH2_k127_8923365_7 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000008402 246.0
PYH2_k127_8923365_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000155 238.0
PYH2_k127_8923365_9 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000008382 203.0
PYH2_k127_8932142_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 403.0
PYH2_k127_8932142_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 306.0
PYH2_k127_8932142_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007691 259.0
PYH2_k127_8932142_3 tRNA pseudouridine synthase activity K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000006897 215.0
PYH2_k127_8932142_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000007446 179.0
PYH2_k127_8932142_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001072 174.0
PYH2_k127_8932142_6 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000003617 132.0
PYH2_k127_8932142_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000005565 125.0
PYH2_k127_8932142_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001069 71.0
PYH2_k127_8939502_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 460.0
PYH2_k127_8939502_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 395.0
PYH2_k127_8939502_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000006103 231.0
PYH2_k127_8939502_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
PYH2_k127_8939502_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000006324 180.0
PYH2_k127_8939502_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000002438 90.0
PYH2_k127_8974219_0 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 599.0
PYH2_k127_8974219_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 503.0
PYH2_k127_8974219_2 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000005704 239.0
PYH2_k127_8974219_3 Heparinase II/III-like protein K20525 - 4.2.2.26 0.00000000000000000000002634 109.0
PYH2_k127_8974219_4 - - - - 0.00000000000000001483 88.0
PYH2_k127_8978559_0 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004606 284.0
PYH2_k127_8978559_1 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 272.0
PYH2_k127_8978559_2 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001888 265.0
PYH2_k127_8978559_3 Peptidase family C25 - - - 0.0000000000000151 81.0
PYH2_k127_8978559_4 Methyltransferase domain protein - - - 0.00007705 51.0
PYH2_k127_8987243_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000008822 249.0
PYH2_k127_8987243_1 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000004474 158.0
PYH2_k127_8987243_2 Zinc-binding dehydrogenase K00055,K00121 - 1.1.1.1,1.1.1.284,1.1.1.90 0.000000000000000000000000000000000000001495 152.0
PYH2_k127_8987243_3 GGDEF domain K13069 - 2.7.7.65 0.000000000000000000000000000000000288 137.0
PYH2_k127_8993065_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 5.532e-302 937.0
PYH2_k127_8993065_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 449.0
PYH2_k127_8993065_2 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 447.0
PYH2_k127_8993065_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 363.0
PYH2_k127_8993065_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003686 290.0
PYH2_k127_8993065_5 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000003593 228.0
PYH2_k127_8993065_6 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000004686 177.0
PYH2_k127_8993065_7 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.0000000000000000000000000000000008951 130.0
PYH2_k127_9020130_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 584.0
PYH2_k127_9020130_1 'ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000001223 171.0
PYH2_k127_9020130_2 Alternative locus ID K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000006868 173.0
PYH2_k127_9021037_0 PLD-like domain - - - 5.039e-232 731.0
PYH2_k127_9021037_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 349.0
PYH2_k127_9021037_2 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000001094 141.0
PYH2_k127_9021037_3 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000001258 86.0
PYH2_k127_9021037_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000007705 84.0
PYH2_k127_9021037_5 Tetratricopeptide repeat - - - 0.0000000000005827 77.0
PYH2_k127_9021037_6 DNA-templated transcription, initiation K03088 - - 0.000007525 49.0
PYH2_k127_90475_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000005715 62.0
PYH2_k127_90475_1 PFAM GAF domain protein - - - 0.0002607 53.0
PYH2_k127_9062448_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.913e-293 929.0
PYH2_k127_9062448_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 294.0
PYH2_k127_9062448_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 253.0
PYH2_k127_9062448_3 HAD superfamily (Subfamily IA) hydrolase, TIGR02254 K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000001583 185.0
PYH2_k127_9062448_4 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000001646 159.0
PYH2_k127_9062448_5 HAD superfamily (Subfamily IA) hydrolase, TIGR02254 K01560 - 3.8.1.2 0.000004639 51.0
PYH2_k127_9079923_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 415.0
PYH2_k127_9079923_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 391.0
PYH2_k127_9079923_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 382.0
PYH2_k127_9079923_3 Histidine kinase K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 295.0
PYH2_k127_9079923_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004667 288.0
PYH2_k127_9079923_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000002465 170.0
PYH2_k127_9079923_6 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000001997 122.0
PYH2_k127_9079923_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000001066 116.0
PYH2_k127_9079923_8 transcriptional regulator K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00006424 50.0
PYH2_k127_9093224_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 9e-323 1007.0
PYH2_k127_9093224_1 metalloendopeptidase activity K08602 - - 2.5e-215 682.0
PYH2_k127_9093224_10 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
PYH2_k127_9093224_11 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000153 232.0
PYH2_k127_9093224_12 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000006573 194.0
PYH2_k127_9093224_13 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000001419 179.0
PYH2_k127_9093224_14 DinB superfamily - - - 0.0000000000000000000000000000000000000001918 161.0
PYH2_k127_9093224_15 acetyltransferase - - - 0.000000000000000000000000000000000004856 144.0
PYH2_k127_9093224_16 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000005238 150.0
PYH2_k127_9093224_17 CoA binding domain K06929 - - 0.0000000000000000000000000000000006742 136.0
PYH2_k127_9093224_18 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000015 122.0
PYH2_k127_9093224_19 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000002507 126.0
PYH2_k127_9093224_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 2.428e-209 663.0
PYH2_k127_9093224_20 - - - - 0.00000000000000000000002195 108.0
PYH2_k127_9093224_21 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000003616 109.0
PYH2_k127_9093224_22 Tetratricopeptide repeat - - - 0.00000000000000001123 97.0
PYH2_k127_9093224_23 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000005966 75.0
PYH2_k127_9093224_24 Family of unknown function (DUF5317) - - - 0.00000003472 64.0
PYH2_k127_9093224_25 Protein of unknown function (DUF1706) - - - 0.00000005758 61.0
PYH2_k127_9093224_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000001693 59.0
PYH2_k127_9093224_3 Response regulator receiver domain K00384 - 1.8.1.9 9.751e-199 633.0
PYH2_k127_9093224_4 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 442.0
PYH2_k127_9093224_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 416.0
PYH2_k127_9093224_6 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 423.0
PYH2_k127_9093224_7 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 366.0
PYH2_k127_9093224_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 323.0
PYH2_k127_9093224_9 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001807 282.0
PYH2_k127_9094372_0 PFAM PBS lyase HEAT-like repeat - - - 0.000000000002768 77.0
PYH2_k127_9094372_1 lytic transglycosylase activity K08307,K08309 - - 0.00008585 53.0
PYH2_k127_9097100_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 430.0
PYH2_k127_9097100_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005056 268.0
PYH2_k127_9097100_10 response regulator receiver K07696,K11624 - - 0.00000000000000000000000000000000000000000000000002768 187.0
PYH2_k127_9097100_11 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000004812 188.0
PYH2_k127_9097100_12 Histidine kinase K11617 - 2.7.13.3 0.000000000000000000000000000000000000000000000281 185.0
PYH2_k127_9097100_13 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000000002692 151.0
PYH2_k127_9097100_14 ATPase histidine kinase DNA gyrase B HSP90 domain protein K00936 - 2.7.13.3 0.0000000000000000000000000000000000006402 151.0
PYH2_k127_9097100_15 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000006459 147.0
PYH2_k127_9097100_16 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000001459 131.0
PYH2_k127_9097100_17 - - - - 0.00000000000000000000000632 113.0
PYH2_k127_9097100_18 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000627 87.0
PYH2_k127_9097100_19 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000009107 90.0
PYH2_k127_9097100_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006841 276.0
PYH2_k127_9097100_20 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.00001222 57.0
PYH2_k127_9097100_22 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0002477 48.0
PYH2_k127_9097100_23 response regulator - - - 0.0004584 47.0
PYH2_k127_9097100_24 anaerobic respiration K02568 - - 0.0005027 53.0
PYH2_k127_9097100_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002632 249.0
PYH2_k127_9097100_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000721 234.0
PYH2_k127_9097100_5 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
PYH2_k127_9097100_6 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000009913 238.0
PYH2_k127_9097100_7 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000000006747 204.0
PYH2_k127_9097100_8 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001029 205.0
PYH2_k127_9097100_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000001713 197.0
PYH2_k127_910329_0 ABC transporter substrate-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 442.0
PYH2_k127_910329_1 ABC transporter permease K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000312 260.0
PYH2_k127_9139126_0 Dienelactone hydrolase family - - - 0.00000006681 64.0
PYH2_k127_9162433_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.0 1098.0
PYH2_k127_9162433_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 4.458e-216 683.0
PYH2_k127_9162433_2 Domain of unknown function (DUF4070) - - - 1.639e-212 671.0
PYH2_k127_9162433_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 455.0
PYH2_k127_9162433_4 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 333.0
PYH2_k127_9162433_5 - - - - 0.0000000000000000000000000000000000000126 147.0
PYH2_k127_9162433_6 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000009111 143.0
PYH2_k127_9162433_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000001002 127.0
PYH2_k127_9169844_0 tryptophan synthase activity K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 610.0
PYH2_k127_9169844_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 608.0
PYH2_k127_9169844_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 474.0
PYH2_k127_9169844_3 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 362.0
PYH2_k127_9169844_4 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000206 158.0
PYH2_k127_9169844_5 GYD domain - - - 0.0000000000000000000000000000000000003679 144.0
PYH2_k127_9169844_6 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000002227 136.0
PYH2_k127_9225761_0 Thiamine pyrophosphate enzyme, central domain - - - 9.404e-224 707.0
PYH2_k127_9225761_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 551.0
PYH2_k127_9225761_11 Auxin binding protein - - - 0.00000000000000000000000000000000000000000000000000000002601 205.0
PYH2_k127_9225761_12 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000002546 178.0
PYH2_k127_9225761_13 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000006187 163.0
PYH2_k127_9225761_14 Pfam:Pyridox_oxidase K09979 - - 0.0000000000000000000000000000493 121.0
PYH2_k127_9225761_15 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000005333 78.0
PYH2_k127_9225761_16 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.00000004434 59.0
PYH2_k127_9225761_17 amine dehydrogenase activity - - - 0.0000004038 60.0
PYH2_k127_9225761_2 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 449.0
PYH2_k127_9225761_3 thiamine-containing compound biosynthetic process K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 389.0
PYH2_k127_9225761_4 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 371.0
PYH2_k127_9225761_5 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 372.0
PYH2_k127_9225761_6 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 314.0
PYH2_k127_9225761_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002857 273.0
PYH2_k127_9225761_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 257.0
PYH2_k127_9225761_9 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006539 224.0
PYH2_k127_9236134_0 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 356.0
PYH2_k127_9236134_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004735 277.0
PYH2_k127_9236134_2 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000001265 245.0
PYH2_k127_9236134_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
PYH2_k127_9236134_4 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.00000000000000000000000000000000000006805 152.0
PYH2_k127_9236134_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000073 111.0
PYH2_k127_9236134_6 - - - - 0.000537 52.0
PYH2_k127_9288058_0 Carbamoyltransferase C-terminus K00612 - - 2.014e-250 785.0
PYH2_k127_9288058_1 NAD(P)H-binding K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 412.0
PYH2_k127_9288058_10 - - - - 0.000001347 53.0
PYH2_k127_9288058_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 385.0
PYH2_k127_9288058_3 PFAM GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 320.0
PYH2_k127_9288058_4 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002328 270.0
PYH2_k127_9288058_5 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001146 234.0
PYH2_k127_9288058_6 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000003406 222.0
PYH2_k127_9288058_7 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000007854 175.0
PYH2_k127_9288058_8 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000003188 170.0
PYH2_k127_9288058_9 - - - - 0.0000000003163 63.0
PYH2_k127_9297584_0 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 503.0
PYH2_k127_9297584_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002545 242.0
PYH2_k127_9299279_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 436.0
PYH2_k127_9299279_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 409.0
PYH2_k127_9299279_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 376.0
PYH2_k127_9299279_3 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
PYH2_k127_9299279_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000003016 244.0
PYH2_k127_9299279_5 PFAM CBS domain containing protein - - - 0.0000000000000000000000000005992 122.0
PYH2_k127_9299279_6 - - - - 0.000009414 53.0
PYH2_k127_9302059_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000007275 222.0
PYH2_k127_9302059_1 Resolvase, N terminal domain K06400 - - 0.000000000000000000000000000000000000002161 166.0
PYH2_k127_957016_0 intracellular signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 447.0
PYH2_k127_957016_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00002192 52.0
PYH2_k127_957016_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0001273 45.0
PYH2_k127_958917_0 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 2.379e-197 631.0
PYH2_k127_958917_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 561.0
PYH2_k127_958917_10 Glycogen debranching enzyme - - - 0.00000000000000000000000000000005643 126.0
PYH2_k127_958917_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 458.0
PYH2_k127_958917_3 Melibiase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 457.0
PYH2_k127_958917_4 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 451.0
PYH2_k127_958917_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 395.0
PYH2_k127_958917_6 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 350.0
PYH2_k127_958917_7 Melibiase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 281.0
PYH2_k127_958917_8 PaaX-like protein K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002422 259.0
PYH2_k127_958917_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000003622 192.0
PYH2_k127_972203_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 581.0
PYH2_k127_972203_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 549.0
PYH2_k127_972203_10 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007371 286.0
PYH2_k127_972203_11 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000004894 239.0
PYH2_k127_972203_12 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000009044 241.0
PYH2_k127_972203_13 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000002023 219.0
PYH2_k127_972203_14 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000003925 161.0
PYH2_k127_972203_15 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000001982 158.0
PYH2_k127_972203_16 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000002404 131.0
PYH2_k127_972203_17 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000143 114.0
PYH2_k127_972203_18 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000005152 103.0
PYH2_k127_972203_19 Protein of unknown function (DUF2283) - - - 0.00000000000000001406 84.0
PYH2_k127_972203_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 515.0
PYH2_k127_972203_20 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00001331 56.0
PYH2_k127_972203_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 365.0
PYH2_k127_972203_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 349.0
PYH2_k127_972203_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 342.0
PYH2_k127_972203_6 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 323.0
PYH2_k127_972203_7 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 316.0
PYH2_k127_972203_8 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 306.0
PYH2_k127_972203_9 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 304.0
PYH2_k127_972877_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1126.0
PYH2_k127_972877_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 380.0
PYH2_k127_972877_2 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 302.0
PYH2_k127_972877_3 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000002381 225.0
PYH2_k127_972877_4 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000009743 173.0
PYH2_k127_972877_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000001303 140.0
PYH2_k127_972877_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000005745 126.0
PYH2_k127_972877_7 PFAM MerR family regulatory protein K13640 - - 0.00000000000000000000000000007381 120.0
PYH2_k127_972877_8 - - - - 0.000000000000000000000000002134 118.0
PYH2_k127_979994_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000003263 188.0
PYH2_k127_999648_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 575.0
PYH2_k127_999648_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 330.0
PYH2_k127_999648_2 elongation factor Tu domain 2 protein K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000009572 225.0
PYH2_k127_999648_3 SMART Excinuclease ABC C subunit domain protein - - - 0.00000000000000000000008068 106.0
PYH2_k127_999648_4 Integrase core domain protein - - - 0.0000000000000000001136 98.0
PYH2_k127_999648_5 Uncharacterised protein family (UPF0158) - - - 0.0000000001063 68.0
PYH2_k127_999648_6 SnoaL-like polyketide cyclase - - - 0.00001273 54.0