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Overview

ID MAG03186
Name PYH2_bin.30
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus Sulfuricurvum
Species
Assembly information
Completeness (%) 78.36
Contamination (%) 0.4
GC content (%) 45.0
N50 (bp) 9,524
Genome size (bp) 1,577,129

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1677

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1000127_0 Multicopper oxidase K22348 - 1.16.3.3 1.07e-268 829.0
PYH2_k127_1000127_1 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 550.0
PYH2_k127_1000127_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 497.0
PYH2_k127_1000127_3 Outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000000000000000000000000003437 208.0
PYH2_k127_1000127_4 Membrane K08984 - - 0.000000000000000000000000000000000000000001632 158.0
PYH2_k127_1001163_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.095e-318 977.0
PYH2_k127_1001163_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.006e-317 980.0
PYH2_k127_1001163_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 344.0
PYH2_k127_1001163_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 293.0
PYH2_k127_1001163_12 membrane - - - 0.0000000000000000000000000000000000000000000004327 168.0
PYH2_k127_1001163_2 outer membrane porin, OprD family - - - 6.081e-210 659.0
PYH2_k127_1001163_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 2.048e-194 611.0
PYH2_k127_1001163_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 581.0
PYH2_k127_1001163_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 526.0
PYH2_k127_1001163_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 474.0
PYH2_k127_1001163_7 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 445.0
PYH2_k127_1001163_8 dna polymerase iii K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 365.0
PYH2_k127_1001163_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 361.0
PYH2_k127_1001825_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1061.0
PYH2_k127_1001825_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 1.29e-199 625.0
PYH2_k127_1001825_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 422.0
PYH2_k127_1001825_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 407.0
PYH2_k127_1001825_4 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
PYH2_k127_1001825_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002303 265.0
PYH2_k127_1001825_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000001385 217.0
PYH2_k127_1024997_0 Belongs to the SEDS family K05837 - - 4.322e-197 621.0
PYH2_k127_1024997_1 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 594.0
PYH2_k127_1024997_2 Fibronectin type 3 domain-containing protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 580.0
PYH2_k127_1024997_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 554.0
PYH2_k127_1024997_4 Cell division protein FtsX K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 403.0
PYH2_k127_1024997_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 305.0
PYH2_k127_1024997_6 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
PYH2_k127_1024997_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000002271 102.0
PYH2_k127_1040067_0 Belongs to the UPF0061 (SELO) family - - - 6.392e-239 745.0
PYH2_k127_1040067_1 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000003922 193.0
PYH2_k127_1040067_2 PFAM CheW domain protein - - - 0.00000000000000000000000000000000000000002732 153.0
PYH2_k127_1046827_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 380.0
PYH2_k127_1046827_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 347.0
PYH2_k127_1046827_2 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 282.0
PYH2_k127_1046827_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000005322 163.0
PYH2_k127_1084518_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1323.0
PYH2_k127_1084518_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 522.0
PYH2_k127_1084518_2 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
PYH2_k127_1084518_3 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 297.0
PYH2_k127_1084518_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000001197 200.0
PYH2_k127_1084518_5 - - - - 0.000000000000000000000000000000002318 133.0
PYH2_k127_1084518_6 AMMECR1 K06990 - - 0.00004552 50.0
PYH2_k127_114555_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.067e-211 663.0
PYH2_k127_114555_1 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 546.0
PYH2_k127_114555_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 442.0
PYH2_k127_114555_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 333.0
PYH2_k127_114555_4 thioesterase K02614 - - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
PYH2_k127_114555_5 Cytochrome c family protein - - - 0.000000000000000000000000000000000000001233 154.0
PYH2_k127_114555_6 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000002601 61.0
PYH2_k127_1173370_0 Heat shock 70 kDa protein K04043 - - 1.754e-277 864.0
PYH2_k127_1173370_1 AAA domain - - - 6.722e-237 758.0
PYH2_k127_1173370_2 Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 350.0
PYH2_k127_1173370_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
PYH2_k127_1173370_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000003806 230.0
PYH2_k127_1173370_5 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000000000000000006752 204.0
PYH2_k127_1207840_0 COG3893 inactivated superfamily I helicase - - - 2.82e-284 893.0
PYH2_k127_1207840_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 313.0
PYH2_k127_1207840_2 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 301.0
PYH2_k127_1207840_3 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005603 258.0
PYH2_k127_1207840_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 255.0
PYH2_k127_1207840_5 Family of unknown function (DUF4006) - - - 0.0000000000000001181 85.0
PYH2_k127_12159_0 Cytochrome c biogenesis protein - - - 0.0 1141.0
PYH2_k127_12159_1 Putative glycosyl hydrolase domain - - - 3.203e-218 683.0
PYH2_k127_12159_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.751e-214 668.0
PYH2_k127_12159_3 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 7.565e-205 645.0
PYH2_k127_12159_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 349.0
PYH2_k127_12159_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 314.0
PYH2_k127_1227959_0 Major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 502.0
PYH2_k127_1227959_1 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 354.0
PYH2_k127_1227959_2 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 344.0
PYH2_k127_1227959_3 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000001001 225.0
PYH2_k127_1227959_4 Flagellar hook protein flgE K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.0000000000000000000000000000000000000000000000000008578 183.0
PYH2_k127_1227959_5 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000002014 134.0
PYH2_k127_1227959_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000007858 103.0
PYH2_k127_1246966_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 3.05e-294 907.0
PYH2_k127_1246966_1 general secretion pathway protein K02247,K02456,K02679,K12285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002927 252.0
PYH2_k127_1247879_0 flagellar - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 397.0
PYH2_k127_1247879_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 302.0
PYH2_k127_1247879_2 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000326 237.0
PYH2_k127_1247879_3 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 K10799 GO:0000209,GO:0000228,GO:0000242,GO:0000723,GO:0000781,GO:0000784,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0012505,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0016757,GO:0016763,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043412,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0045732,GO:0045862,GO:0045934,GO:0045935,GO:0046483,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051246,GO:0051247,GO:0051276,GO:0051641,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0071704,GO:0071840,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0098687,GO:1901360,GO:1901564,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001251,GO:2001252 2.4.2.30 0.00000000002568 74.0
PYH2_k127_1247967_0 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1241.0
PYH2_k127_1247967_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K14086 - - 1.836e-238 750.0
PYH2_k127_1247967_10 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000003742 231.0
PYH2_k127_1247967_11 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000666 193.0
PYH2_k127_1247967_12 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 0.0000000000000000000000000000000000000000000000004545 178.0
PYH2_k127_1247967_13 Uncharacterized lipoprotein K07286 - - 0.000000000000000000000000000000008412 132.0
PYH2_k127_1247967_14 Membrane - - - 0.000000000000000000000000003668 112.0
PYH2_k127_1247967_15 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000005605 104.0
PYH2_k127_1247967_2 Hydrogenase-4, component G K14090 - - 1.798e-212 662.0
PYH2_k127_1247967_3 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 518.0
PYH2_k127_1247967_4 NADH dehydrogenase K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 446.0
PYH2_k127_1247967_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 334.0
PYH2_k127_1247967_6 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 331.0
PYH2_k127_1247967_7 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 307.0
PYH2_k127_1247967_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K14091 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000003197 246.0
PYH2_k127_1247967_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
PYH2_k127_12887_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 3.111e-227 707.0
PYH2_k127_12887_1 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 500.0
PYH2_k127_12887_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 445.0
PYH2_k127_12887_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 335.0
PYH2_k127_12887_4 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 319.0
PYH2_k127_12887_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000001457 236.0
PYH2_k127_1337659_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1051.0
PYH2_k127_1337659_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.284e-293 905.0
PYH2_k127_1337659_10 Transcriptional regulator K13640 - - 0.0000000000000000000000000000000000000000000000000000000000000002673 221.0
PYH2_k127_1337659_11 nucleoside-diphosphate sugar epimerase K07071 - - 0.00000000000000000000000000000000000000000000000003188 190.0
PYH2_k127_1337659_12 - - - - 0.00000000000000000000000000000000000000000000000366 174.0
PYH2_k127_1337659_13 - - - - 0.0000000000000000000000000000000000000000000000189 172.0
PYH2_k127_1337659_14 transport system auxiliary component K18480 - - 0.000000000000000000000000000000000000000000005048 171.0
PYH2_k127_1337659_15 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000002818 160.0
PYH2_k127_1337659_16 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000579 68.0
PYH2_k127_1337659_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 557.0
PYH2_k127_1337659_3 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
PYH2_k127_1337659_4 Co-chaperone-curved DNA binding protein A K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
PYH2_k127_1337659_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 473.0
PYH2_k127_1337659_6 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
PYH2_k127_1337659_7 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
PYH2_k127_1337659_8 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 332.0
PYH2_k127_1337659_9 G T U mismatch-specific DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 236.0
PYH2_k127_136220_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.502e-267 825.0
PYH2_k127_136220_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 485.0
PYH2_k127_136220_2 lytic murein transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 389.0
PYH2_k127_136220_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 286.0
PYH2_k127_136220_4 - - - - 0.000000000000000004814 85.0
PYH2_k127_136220_5 - - - - 0.000002413 56.0
PYH2_k127_139550_0 acetolactate synthase K01652 - 2.2.1.6 7.087e-319 978.0
PYH2_k127_139550_1 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 396.0
PYH2_k127_139550_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001784 188.0
PYH2_k127_139550_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000001446 83.0
PYH2_k127_1414641_0 ATP citrate synthase K15230 - 2.3.3.8 0.0 1161.0
PYH2_k127_1414641_1 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 1.125e-285 878.0
PYH2_k127_1414641_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003109 254.0
PYH2_k127_1423308_0 growth of symbiont in host cell K07003 - - 3.338e-261 822.0
PYH2_k127_1423308_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 496.0
PYH2_k127_1423308_2 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000001519 220.0
PYH2_k127_1423308_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000004843 173.0
PYH2_k127_1423308_4 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000003767 183.0
PYH2_k127_1423308_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000001485 164.0
PYH2_k127_1423308_6 - - - - 0.00000000000000000004235 94.0
PYH2_k127_1476885_0 TonB dependent receptor K16092 - - 8.226e-199 636.0
PYH2_k127_1476885_1 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 333.0
PYH2_k127_151750_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 476.0
PYH2_k127_151750_1 Major facilitator superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000002509 219.0
PYH2_k127_151750_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000006209 208.0
PYH2_k127_151750_3 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000004084 134.0
PYH2_k127_1607685_0 B-1 B cell differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 443.0
PYH2_k127_1607685_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001021 282.0
PYH2_k127_1607685_2 Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000001721 231.0
PYH2_k127_1607685_3 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000000000000006516 186.0
PYH2_k127_1607685_4 - - - - 0.00000000000000000000000000000000001426 143.0
PYH2_k127_1660405_0 penicillin-binding protein K05515 - 3.4.16.4 5.215e-311 961.0
PYH2_k127_1660405_1 May be involved in recombinational repair of damaged DNA K03631 - - 4.926e-221 695.0
PYH2_k127_1660405_10 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
PYH2_k127_1660405_11 hmm pf01863 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
PYH2_k127_1660405_12 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
PYH2_k127_1660405_13 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000001803 227.0
PYH2_k127_1660405_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000001115 207.0
PYH2_k127_1660405_15 - - - - 0.000000000000000000000000000000000000000000000000003472 186.0
PYH2_k127_1660405_16 - - - - 0.00000000000000000000000000000002034 131.0
PYH2_k127_1660405_17 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000006914 118.0
PYH2_k127_1660405_2 lytic murein transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 560.0
PYH2_k127_1660405_3 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 550.0
PYH2_k127_1660405_4 hydrolase, TatD K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 433.0
PYH2_k127_1660405_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 411.0
PYH2_k127_1660405_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 373.0
PYH2_k127_1660405_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 366.0
PYH2_k127_1660405_8 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 328.0
PYH2_k127_1660405_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
PYH2_k127_1709939_0 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 5.749e-266 827.0
PYH2_k127_1709939_1 COG2223 Nitrate nitrite transporter K02575 - - 5.722e-242 758.0
PYH2_k127_1709939_2 RNA binding S1 domain protein K06959 - - 0.000000000000000000000000000000001451 129.0
PYH2_k127_17376_0 Phosphoesterase family K01114 - 3.1.4.3 1.045e-219 689.0
PYH2_k127_17376_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 428.0
PYH2_k127_17376_2 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
PYH2_k127_17376_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 373.0
PYH2_k127_17376_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 285.0
PYH2_k127_17376_5 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003126 299.0
PYH2_k127_17376_6 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000000000004948 201.0
PYH2_k127_17376_7 of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000000000000000000022 138.0
PYH2_k127_17376_8 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000001312 102.0
PYH2_k127_17376_9 Rubredoxin - - - 0.00000000000000000001751 92.0
PYH2_k127_178570_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000002055 250.0
PYH2_k127_178570_1 PAS domain - - - 0.0000000000000000000000000003092 127.0
PYH2_k127_178570_2 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000001707 109.0
PYH2_k127_178570_3 response regulator K03413 - - 0.0000000000000000004599 102.0
PYH2_k127_183483_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 7.623e-321 985.0
PYH2_k127_183483_1 - - - - 0.00000000000000000000175 94.0
PYH2_k127_1875716_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 4.493e-255 797.0
PYH2_k127_1875716_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 557.0
PYH2_k127_1875716_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 560.0
PYH2_k127_193703_0 arginine decarboxylase K01585 - 4.1.1.19 0.0 1166.0
PYH2_k127_193703_1 COGs COG0069 Glutamate synthase domain 2 - - - 3.751e-238 749.0
PYH2_k127_193703_2 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 424.0
PYH2_k127_193703_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000001409 64.0
PYH2_k127_193703_4 LPP20 lipoprotein - - - 0.0000001336 62.0
PYH2_k127_2003922_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 - 2.7.7.6 0.0 2821.0
PYH2_k127_2003922_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2072.0
PYH2_k127_2003922_10 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 513.0
PYH2_k127_2003922_11 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 459.0
PYH2_k127_2003922_12 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 439.0
PYH2_k127_2003922_13 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 424.0
PYH2_k127_2003922_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 423.0
PYH2_k127_2003922_15 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 420.0
PYH2_k127_2003922_16 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 418.0
PYH2_k127_2003922_17 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 340.0
PYH2_k127_2003922_18 Belongs to the UPF0246 family K09861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 331.0
PYH2_k127_2003922_19 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 296.0
PYH2_k127_2003922_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1356.0
PYH2_k127_2003922_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 291.0
PYH2_k127_2003922_21 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004976 273.0
PYH2_k127_2003922_22 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 272.0
PYH2_k127_2003922_23 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000209 243.0
PYH2_k127_2003922_24 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 242.0
PYH2_k127_2003922_25 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000007741 225.0
PYH2_k127_2003922_26 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
PYH2_k127_2003922_27 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000000000005666 211.0
PYH2_k127_2003922_29 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000000000000000006687 161.0
PYH2_k127_2003922_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1170.0
PYH2_k127_2003922_30 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000173 102.0
PYH2_k127_2003922_31 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000004427 91.0
PYH2_k127_2003922_32 Thioredoxin - - - 0.00000000000000000006786 95.0
PYH2_k127_2003922_4 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0 1015.0
PYH2_k127_2003922_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.4e-248 769.0
PYH2_k127_2003922_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 6.437e-213 670.0
PYH2_k127_2003922_7 Belongs to the SEDS family K03588 - - 1.373e-200 632.0
PYH2_k127_2003922_8 Sodium calcium exchanger membrane K07300 - - 2.636e-197 619.0
PYH2_k127_2003922_9 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 550.0
PYH2_k127_2020302_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 4.408e-227 721.0
PYH2_k127_2020302_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 547.0
PYH2_k127_2020302_10 Paralysed flagella protein - - - 0.000000000000003177 76.0
PYH2_k127_2020302_2 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 441.0
PYH2_k127_2020302_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 371.0
PYH2_k127_2020302_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 338.0
PYH2_k127_2020302_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
PYH2_k127_2020302_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001744 233.0
PYH2_k127_2020302_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH2_k127_2020302_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
PYH2_k127_2020302_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000003518 193.0
PYH2_k127_2022172_0 Heat shock 70 kDa protein K04043 - - 1.996e-283 872.0
PYH2_k127_2022172_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 317.0
PYH2_k127_2022172_2 COG0471 Di- and tricarboxylate K03319 - - 0.000000000000000000000000000000000000000004454 157.0
PYH2_k127_2028542_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 425.0
PYH2_k127_2028542_1 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 378.0
PYH2_k127_2028542_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000002896 231.0
PYH2_k127_2028542_3 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000000000000000000000004796 219.0
PYH2_k127_2028542_4 endonuclease containing a URI domain K07461 - - 0.000000000000000000000001518 105.0
PYH2_k127_2028542_5 Protein of unknown function (DUF3108) - - - 0.00000000000000007487 80.0
PYH2_k127_2028542_6 His Kinase A (phosphoacceptor) domain - - - 0.0000663 50.0
PYH2_k127_2039391_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 5.174e-308 947.0
PYH2_k127_2039391_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.858e-276 851.0
PYH2_k127_2039391_10 Flagellar biosynthetic protein fliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 411.0
PYH2_k127_2039391_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 346.0
PYH2_k127_2039391_12 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
PYH2_k127_2039391_13 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 292.0
PYH2_k127_2039391_14 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001615 276.0
PYH2_k127_2039391_15 RESPONSE REGULATOR receiver K07288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006463 291.0
PYH2_k127_2039391_16 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
PYH2_k127_2039391_17 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000006186 240.0
PYH2_k127_2039391_18 Hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000002056 201.0
PYH2_k127_2039391_19 Protein of unknown function (DUF2393) - - - 0.00000000000000000000000000000000000000000000000009673 182.0
PYH2_k127_2039391_2 Belongs to the aldehyde dehydrogenase family - - - 2.146e-257 798.0
PYH2_k127_2039391_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000001151 104.0
PYH2_k127_2039391_21 Protein of unknown function (DUF2393) - - - 0.00000000000004046 79.0
PYH2_k127_2039391_3 Protein of unknown function (DUF3373) - - - 1.814e-237 743.0
PYH2_k127_2039391_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 8.387e-197 617.0
PYH2_k127_2039391_5 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 590.0
PYH2_k127_2039391_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 587.0
PYH2_k127_2039391_7 Radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 556.0
PYH2_k127_2039391_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 459.0
PYH2_k127_2039391_9 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 417.0
PYH2_k127_20704_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 599.0
PYH2_k127_20704_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 501.0
PYH2_k127_20704_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 332.0
PYH2_k127_20704_3 GAF domain - - - 0.000000004072 68.0
PYH2_k127_20704_4 FecR protein - - - 0.0002055 51.0
PYH2_k127_208469_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.678e-228 712.0
PYH2_k127_208469_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
PYH2_k127_208469_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 380.0
PYH2_k127_208469_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 350.0
PYH2_k127_208469_4 ATP synthase K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 288.0
PYH2_k127_208469_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000003132 147.0
PYH2_k127_209561_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1318.0
PYH2_k127_209561_1 ABC transporter, ATP-binding protein K15738 - - 0.0 1114.0
PYH2_k127_209561_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 347.0
PYH2_k127_209561_11 Superoxide dismutase K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
PYH2_k127_209561_12 COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain) K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 287.0
PYH2_k127_209561_13 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001868 265.0
PYH2_k127_209561_14 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
PYH2_k127_209561_15 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
PYH2_k127_209561_16 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000001149 214.0
PYH2_k127_209561_19 Stress responsive A B Barrel Domain - - - 0.000000000000000000000000000000000000002075 148.0
PYH2_k127_209561_2 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 5.741e-301 934.0
PYH2_k127_209561_3 4Fe-4S dicluster domain K07307 - - 4.42e-285 881.0
PYH2_k127_209561_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.426e-271 839.0
PYH2_k127_209561_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.366e-264 840.0
PYH2_k127_209561_6 potassium channel protein K10716 - - 3.418e-203 644.0
PYH2_k127_209561_7 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 503.0
PYH2_k127_209561_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 413.0
PYH2_k127_209561_9 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 419.0
PYH2_k127_2125984_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 3.148e-221 692.0
PYH2_k127_2125984_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 527.0
PYH2_k127_2125984_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 338.0
PYH2_k127_2125984_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
PYH2_k127_2125984_4 Jag_N K06346 - - 0.000000000000000000000000000000000000000000000003071 183.0
PYH2_k127_214754_0 Aminotransferase K00812 - 2.6.1.1 6.576e-226 702.0
PYH2_k127_214754_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 486.0
PYH2_k127_214754_2 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008898 276.0
PYH2_k127_214754_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004569 267.0
PYH2_k127_214754_4 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000004125 192.0
PYH2_k127_214754_5 acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000273 184.0
PYH2_k127_214754_6 - - - - 0.00000000000000000000000000000003158 126.0
PYH2_k127_2176746_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 4.645e-244 755.0
PYH2_k127_2176746_1 glutamine synthetase K01915 - 6.3.1.2 1.167e-205 640.0
PYH2_k127_2183763_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1137.0
PYH2_k127_2183763_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.537e-269 835.0
PYH2_k127_2183763_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 414.0
PYH2_k127_2183763_11 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 380.0
PYH2_k127_2183763_12 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 361.0
PYH2_k127_2183763_13 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 319.0
PYH2_k127_2183763_14 transformation system protein K02242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 309.0
PYH2_k127_2183763_15 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
PYH2_k127_2183763_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001366 136.0
PYH2_k127_2183763_17 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000001871 118.0
PYH2_k127_2183763_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.202e-248 769.0
PYH2_k127_2183763_3 Chemotaxis phosphatase CheX - - - 2.113e-236 737.0
PYH2_k127_2183763_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 2.483e-235 732.0
PYH2_k127_2183763_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 1.17e-222 694.0
PYH2_k127_2183763_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.548e-201 630.0
PYH2_k127_2183763_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 572.0
PYH2_k127_2183763_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 571.0
PYH2_k127_2183763_9 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 432.0
PYH2_k127_2321976_0 diguanylate cyclase - - - 1.759e-206 660.0
PYH2_k127_2321976_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 346.0
PYH2_k127_2321976_2 chain release factor K15034 - - 0.00000000000000000006451 89.0
PYH2_k127_2321976_3 diguanylate cyclase - - - 0.0000000000001313 78.0
PYH2_k127_2371035_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1394.0
PYH2_k127_2371035_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0 1030.0
PYH2_k127_2371035_2 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 2.689e-290 896.0
PYH2_k127_2371035_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.995e-277 856.0
PYH2_k127_2371035_4 Paralysed flagella protein - - - 1.763e-267 844.0
PYH2_k127_2371035_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 5.484e-196 614.0
PYH2_k127_2371035_6 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 475.0
PYH2_k127_2371035_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 400.0
PYH2_k127_2371035_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 283.0
PYH2_k127_2371035_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000007322 173.0
PYH2_k127_240324_0 DNA helicase K03657 - 3.6.4.12 0.0 1197.0
PYH2_k127_240324_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 531.0
PYH2_k127_240324_10 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000000003873 149.0
PYH2_k127_240324_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000006669 130.0
PYH2_k127_240324_12 Global regulator protein family - - - 0.00001145 50.0
PYH2_k127_240324_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 445.0
PYH2_k127_240324_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 424.0
PYH2_k127_240324_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 417.0
PYH2_k127_240324_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000844 279.0
PYH2_k127_240324_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001706 272.0
PYH2_k127_240324_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 252.0
PYH2_k127_240324_8 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000003492 245.0
PYH2_k127_240324_9 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000005173 209.0
PYH2_k127_2414105_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 1.296e-309 952.0
PYH2_k127_2414105_1 Type II secretion system K02455,K12278 - - 1.848e-212 665.0
PYH2_k127_2414105_2 DNA helicase K03657 - 3.6.4.12 0.00000000002526 64.0
PYH2_k127_2453531_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.443e-288 889.0
PYH2_k127_2453531_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.772e-256 790.0
PYH2_k127_2453531_10 Flagellar FliJ protein - - - 0.000000000000000000000000000001237 126.0
PYH2_k127_2453531_11 cytochrome c oxidase K00407 - - 0.00000000000000000000000005675 108.0
PYH2_k127_2453531_2 Belongs to the CarA family K01956 - 6.3.5.5 1.793e-216 675.0
PYH2_k127_2453531_3 Aminotransferase - - - 2.873e-202 634.0
PYH2_k127_2453531_4 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 450.0
PYH2_k127_2453531_5 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 414.0
PYH2_k127_2453531_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 381.0
PYH2_k127_2453531_7 protein conserved in bacteria K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 297.0
PYH2_k127_2453531_8 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000173 232.0
PYH2_k127_2453531_9 PDP protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005118 229.0
PYH2_k127_25000_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 318.0
PYH2_k127_25000_1 Phytochrome central region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000324 226.0
PYH2_k127_25000_2 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000001973 218.0
PYH2_k127_25000_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000000005164 109.0
PYH2_k127_25000_4 Heme oxygenase - - - 0.0000000003782 68.0
PYH2_k127_263827_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1760.0
PYH2_k127_263827_1 RND efflux system, outer membrane lipoprotein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 475.0
PYH2_k127_263827_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000002918 227.0
PYH2_k127_263827_3 HlyD family secretion protein K03543 - - 0.000000000000000000000000000000006948 137.0
PYH2_k127_2716060_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1150.0
PYH2_k127_2716060_1 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 2.475e-217 683.0
PYH2_k127_2716060_2 Histidine kinase K02484 - 2.7.13.3 4.187e-213 668.0
PYH2_k127_2716060_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 441.0
PYH2_k127_2716060_4 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 418.0
PYH2_k127_2716060_5 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 335.0
PYH2_k127_2716060_6 Ferredoxin K05337 - - 0.000000000000000000000000000000000000000000003047 164.0
PYH2_k127_2716060_7 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000003239 134.0
PYH2_k127_2716060_8 - - - - 0.000000000000000000000000003764 115.0
PYH2_k127_2716060_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000008041 94.0
PYH2_k127_2722867_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.361e-240 746.0
PYH2_k127_2722867_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 452.0
PYH2_k127_2722867_2 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 435.0
PYH2_k127_2722867_3 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 387.0
PYH2_k127_2722867_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
PYH2_k127_2722867_5 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000002222 79.0
PYH2_k127_2803189_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1021.0
PYH2_k127_2803189_1 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 4.188e-270 838.0
PYH2_k127_2803189_10 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 386.0
PYH2_k127_2803189_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 360.0
PYH2_k127_2803189_12 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 344.0
PYH2_k127_2803189_13 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 310.0
PYH2_k127_2803189_14 - - - - 0.0000000000000000000000000000000000000000000000000000000132 201.0
PYH2_k127_2803189_15 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000000000000000000000000000001065 175.0
PYH2_k127_2803189_16 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000412 166.0
PYH2_k127_2803189_18 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000002047 120.0
PYH2_k127_2803189_19 - - - - 0.000000000000004737 76.0
PYH2_k127_2803189_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.534e-235 738.0
PYH2_k127_2803189_20 - - - - 0.000002525 49.0
PYH2_k127_2803189_3 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 1.794e-233 729.0
PYH2_k127_2803189_4 COG4886 Leucine-rich repeat (LRR) protein - - - 1.658e-210 660.0
PYH2_k127_2803189_5 FAD binding domain K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 605.0
PYH2_k127_2803189_6 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 472.0
PYH2_k127_2803189_7 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 428.0
PYH2_k127_2803189_8 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 408.0
PYH2_k127_2803189_9 Abc transporter K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 393.0
PYH2_k127_2853917_0 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 455.0
PYH2_k127_2853917_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000002009 212.0
PYH2_k127_2853917_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000001103 175.0
PYH2_k127_2865550_0 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 552.0
PYH2_k127_2865550_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 547.0
PYH2_k127_2865550_2 dehydrogenase K00076 - 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 500.0
PYH2_k127_2865550_3 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 499.0
PYH2_k127_2865550_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
PYH2_k127_2865550_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 296.0
PYH2_k127_286859_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1499.0
PYH2_k127_286859_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 3.964e-241 750.0
PYH2_k127_286859_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 626.0
PYH2_k127_286859_3 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 548.0
PYH2_k127_286859_4 protein-glutamate methylesterase activity K00575,K03412,K03413 - 2.1.1.80,3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 370.0
PYH2_k127_286859_5 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 297.0
PYH2_k127_286859_6 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000005392 212.0
PYH2_k127_286859_7 Signal transduction protein - - - 0.0000000000000000000000001438 107.0
PYH2_k127_2872712_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 3.987e-265 824.0
PYH2_k127_2872712_1 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 611.0
PYH2_k127_2872712_2 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 556.0
PYH2_k127_2872712_3 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 388.0
PYH2_k127_2872712_4 Chaperone for flagella basal body P-ring formation K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 289.0
PYH2_k127_2872712_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000003675 231.0
PYH2_k127_2872712_6 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000002067 211.0
PYH2_k127_2873262_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0 1136.0
PYH2_k127_2873262_1 ribosomal protein S1 K02945 - - 5e-324 996.0
PYH2_k127_2873262_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000005925 72.0
PYH2_k127_2873262_2 argininosuccinate lyase K01755 - 4.3.2.1 3.685e-259 802.0
PYH2_k127_2873262_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 3.137e-235 734.0
PYH2_k127_2873262_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 3.751e-206 643.0
PYH2_k127_2873262_5 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 492.0
PYH2_k127_2873262_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 471.0
PYH2_k127_2873262_7 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 293.0
PYH2_k127_2873262_8 Hit family K02503 - - 0.00000000000000000000000000000000000000000000000000000000000000004545 224.0
PYH2_k127_2873262_9 - - - - 0.000000000000000000000000000000000000000002122 160.0
PYH2_k127_2892085_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 456.0
PYH2_k127_2892085_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 439.0
PYH2_k127_2892085_2 chemotaxis protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 424.0
PYH2_k127_2892085_3 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004773 248.0
PYH2_k127_2892085_4 PFAM response regulator receiver K03407,K03413 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000005445 206.0
PYH2_k127_2892085_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000001656 211.0
PYH2_k127_2892085_6 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000003599 183.0
PYH2_k127_2895354_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1178.0
PYH2_k127_2895354_1 Abc transporter K06158 - - 0.0 1075.0
PYH2_k127_2895354_2 phosphohydrolase (DHH superfamily) K07097 - - 8.465e-210 654.0
PYH2_k127_2895354_3 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 550.0
PYH2_k127_2895354_4 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 383.0
PYH2_k127_2895354_5 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 289.0
PYH2_k127_2895354_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
PYH2_k127_2895354_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000003457 153.0
PYH2_k127_28996_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 508.0
PYH2_k127_28996_1 component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 452.0
PYH2_k127_28996_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 282.0
PYH2_k127_28996_3 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000001207 112.0
PYH2_k127_28996_4 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000001735 91.0
PYH2_k127_290122_0 Thiol disulfide interchange protein K04084 - 1.8.1.8 1.746e-261 817.0
PYH2_k127_290122_1 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000000000000001579 228.0
PYH2_k127_290122_2 Pentapeptide repeat protein - - - 0.00000000000000000000000000000000000000000000000004183 181.0
PYH2_k127_290122_3 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000008892 177.0
PYH2_k127_290122_4 PFAM DsrE family protein K06039 - - 0.00000000000004296 71.0
PYH2_k127_2908266_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 2.231e-199 625.0
PYH2_k127_2908266_1 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 414.0
PYH2_k127_2947020_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.137e-246 764.0
PYH2_k127_2947020_1 lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 496.0
PYH2_k127_2947020_2 PFAM Type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 323.0
PYH2_k127_2947020_3 YGGT family K02221 - - 0.000000000000000000000000000000000000000001135 158.0
PYH2_k127_3000967_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 589.0
PYH2_k127_3000967_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 561.0
PYH2_k127_3000967_2 Peptidase s1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 533.0
PYH2_k127_3000967_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 430.0
PYH2_k127_3000967_4 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 316.0
PYH2_k127_3000967_5 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000001652 124.0
PYH2_k127_3000967_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000003608 117.0
PYH2_k127_3088199_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.234e-229 714.0
PYH2_k127_3088199_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 291.0
PYH2_k127_3088199_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000007166 107.0
PYH2_k127_310735_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K17050 - - 0.0 1857.0
PYH2_k127_310735_1 4Fe-4S dicluster domain K17051 - - 4.298e-241 745.0
PYH2_k127_310735_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 3.953e-197 621.0
PYH2_k127_310735_3 Cytochrome c-552 DMSO reductase-like, heme-binding domain K17052 - - 2.865e-196 617.0
PYH2_k127_310735_4 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 329.0
PYH2_k127_310735_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
PYH2_k127_3147804_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 606.0
PYH2_k127_3147804_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 383.0
PYH2_k127_3147804_2 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000002179 143.0
PYH2_k127_3147804_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0002543 44.0
PYH2_k127_3170_0 Ribonuclease K12573 - - 0.0 1085.0
PYH2_k127_3170_1 DNA polymerase III K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 539.0
PYH2_k127_3170_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 358.0
PYH2_k127_3170_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 304.0
PYH2_k127_3170_4 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
PYH2_k127_3170_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 294.0
PYH2_k127_3170_6 - - - - 0.0000000000000000000000000000000000000000000000009858 175.0
PYH2_k127_3201136_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.5e-323 994.0
PYH2_k127_3201136_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000001027 202.0
PYH2_k127_3201136_2 - - - - 0.00000000000000000000000000000000000000000000009327 172.0
PYH2_k127_3201136_3 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000004312 93.0
PYH2_k127_3201136_4 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000001392 55.0
PYH2_k127_3213047_0 silver ion transport K07787,K15726 - - 0.0 1071.0
PYH2_k127_3213047_1 Belongs to the heme-copper respiratory oxidase family - - - 2.564e-223 702.0
PYH2_k127_3213047_11 - - - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
PYH2_k127_3213047_12 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000001476 158.0
PYH2_k127_3213047_13 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.000000000002406 78.0
PYH2_k127_3213047_14 Belongs to the UPF0312 family - - - 0.000002842 56.0
PYH2_k127_3213047_2 - - - - 1.208e-195 616.0
PYH2_k127_3213047_3 ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 536.0
PYH2_k127_3213047_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 463.0
PYH2_k127_3213047_6 - K21817 - 1.13.11.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 405.0
PYH2_k127_3213047_7 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 267.0
PYH2_k127_3213047_8 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005954 256.0
PYH2_k127_3213047_9 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006529 252.0
PYH2_k127_3390738_0 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 410.0
PYH2_k127_3390738_1 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
PYH2_k127_3390738_2 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000001893 179.0
PYH2_k127_3390738_3 alanine dehydrogenase K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000001057 168.0
PYH2_k127_3414461_0 Oxidoreductase K00174 - 1.2.7.11,1.2.7.3 3.575e-196 616.0
PYH2_k127_3414461_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 541.0
PYH2_k127_3414461_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 537.0
PYH2_k127_3414461_3 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 515.0
PYH2_k127_3414461_4 oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 312.0
PYH2_k127_3414461_5 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000003942 190.0
PYH2_k127_3414461_6 2-oxoglutarate acceptor oxidoreductase K00176 - 1.2.7.3 0.000000000000000000000000000000000000000000004704 164.0
PYH2_k127_3414461_7 Heavy-metal-associated domain - - - 0.000000000000000000000000000000001502 132.0
PYH2_k127_3414461_9 - - - - 0.0000004489 52.0
PYH2_k127_3440559_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 372.0
PYH2_k127_3440559_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000000000000000000000006865 194.0
PYH2_k127_3440559_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000006909 126.0
PYH2_k127_3440559_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000004169 86.0
PYH2_k127_347756_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.429e-232 722.0
PYH2_k127_347756_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 6.21e-197 619.0
PYH2_k127_347756_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 532.0
PYH2_k127_347756_3 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 476.0
PYH2_k127_347756_4 - K12065 - - 0.00000000000000000000000000000000000000000000000000007818 200.0
PYH2_k127_347756_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000000004848 136.0
PYH2_k127_347756_6 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000002294 75.0
PYH2_k127_3774071_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1186.0
PYH2_k127_3774071_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1148.0
PYH2_k127_3774071_10 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 439.0
PYH2_k127_3774071_11 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 423.0
PYH2_k127_3774071_12 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 411.0
PYH2_k127_3774071_13 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 389.0
PYH2_k127_3774071_14 Histidine kinase A domain protein K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 402.0
PYH2_k127_3774071_15 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 372.0
PYH2_k127_3774071_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 371.0
PYH2_k127_3774071_17 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 322.0
PYH2_k127_3774071_18 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 320.0
PYH2_k127_3774071_19 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 329.0
PYH2_k127_3774071_2 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.0 1135.0
PYH2_k127_3774071_20 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 315.0
PYH2_k127_3774071_21 Abc transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 317.0
PYH2_k127_3774071_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 312.0
PYH2_k127_3774071_23 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 304.0
PYH2_k127_3774071_24 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 292.0
PYH2_k127_3774071_25 Histidine kinase K07678 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000753 311.0
PYH2_k127_3774071_26 COGs COG3786 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 267.0
PYH2_k127_3774071_27 Protein of unknown function (DUF3972) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002111 246.0
PYH2_k127_3774071_28 translation initiation factor activity K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001649 247.0
PYH2_k127_3774071_29 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001701 246.0
PYH2_k127_3774071_3 cobalamin-transporting ATPase activity K02014 - - 0.0 1086.0
PYH2_k127_3774071_30 Transcriptional regulator K15973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003291 240.0
PYH2_k127_3774071_31 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005703 245.0
PYH2_k127_3774071_32 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000001527 217.0
PYH2_k127_3774071_35 - - - - 0.0000000000000000000000001704 106.0
PYH2_k127_3774071_4 K+ potassium transporter K03549 - - 4.55e-320 988.0
PYH2_k127_3774071_5 peptidase U32 family K08303 - - 5.642e-262 810.0
PYH2_k127_3774071_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 592.0
PYH2_k127_3774071_7 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 591.0
PYH2_k127_3774071_8 Cytochrome K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 549.0
PYH2_k127_3774071_9 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 526.0
PYH2_k127_3799047_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1740.0
PYH2_k127_3799047_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.499e-288 887.0
PYH2_k127_3799047_10 Membrane K08984 - - 0.000000000000000000000000000000000000000000000000000005082 193.0
PYH2_k127_3799047_11 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000001711 100.0
PYH2_k127_3799047_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.148e-265 820.0
PYH2_k127_3799047_3 o-acetylhomoserine K01740 - 2.5.1.49 6.923e-240 745.0
PYH2_k127_3799047_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.338e-220 686.0
PYH2_k127_3799047_5 Belongs to the CinA family K03743 - 3.5.1.42 2.054e-194 612.0
PYH2_k127_3799047_6 hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 465.0
PYH2_k127_3799047_7 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 386.0
PYH2_k127_3799047_8 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 360.0
PYH2_k127_3799047_9 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 301.0
PYH2_k127_3806231_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 444.0
PYH2_k127_3806231_1 TIGRFAM diguanylate cyclase (GGDEF) domain K13069,K13590,K18967 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 424.0
PYH2_k127_3806231_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004693 246.0
PYH2_k127_3892527_0 Sulfatase - - - 0.0 1011.0
PYH2_k127_3892527_1 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 2.526e-229 724.0
PYH2_k127_3892527_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007017 256.0
PYH2_k127_3892527_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000002256 233.0
PYH2_k127_3901457_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1285.0
PYH2_k127_3901457_1 Signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 392.0
PYH2_k127_3919972_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1825.0
PYH2_k127_3919972_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.386e-230 718.0
PYH2_k127_3919972_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000002441 231.0
PYH2_k127_3919972_11 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000006466 228.0
PYH2_k127_3919972_12 Diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000007969 206.0
PYH2_k127_3919972_13 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000001602 139.0
PYH2_k127_3919972_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 1.302e-218 683.0
PYH2_k127_3919972_3 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 545.0
PYH2_k127_3919972_4 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 445.0
PYH2_k127_3919972_5 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 398.0
PYH2_k127_3919972_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 362.0
PYH2_k127_3919972_7 RecO N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 331.0
PYH2_k127_3919972_8 Peptidase A24 K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
PYH2_k127_3919972_9 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 274.0
PYH2_k127_3972337_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.091e-319 989.0
PYH2_k127_3972337_1 Belongs to the GARS family K01945 - 6.3.4.13 4.615e-252 784.0
PYH2_k127_3972337_2 MlaD protein K02067 - - 6.127e-244 759.0
PYH2_k127_3972337_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 578.0
PYH2_k127_3972337_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 366.0
PYH2_k127_3972337_5 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000001502 230.0
PYH2_k127_3972337_6 RDD family - - - 0.000000000000000000000000005808 115.0
PYH2_k127_403778_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1128.0
PYH2_k127_403778_1 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004144 245.0
PYH2_k127_403778_2 4Fe-4S binding domain K02572 - - 0.00000000000000000000000000000000000000000000000000000000000000000002182 235.0
PYH2_k127_403778_3 nitrate reductase K02570 - - 0.0000000000000000000000000000000000000000000000000000000001381 204.0
PYH2_k127_403778_4 Diguanylate cyclase - - - 0.000000000000000000001888 97.0
PYH2_k127_4092652_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 6.239e-319 997.0
PYH2_k127_4092652_1 Two-component sensor histidine kinase response regulator - - - 3.54e-207 674.0
PYH2_k127_4092652_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 388.0
PYH2_k127_4092652_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000005612 194.0
PYH2_k127_4092652_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000001081 85.0
PYH2_k127_4092652_5 Outer membrane efflux protein K15725 - - 0.00000000000000000162 98.0
PYH2_k127_4139893_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 548.0
PYH2_k127_4139893_1 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 509.0
PYH2_k127_4139893_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 389.0
PYH2_k127_4139893_3 - - - - 0.0000000000001108 72.0
PYH2_k127_4154649_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1104.0
PYH2_k127_4154649_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000176 115.0
PYH2_k127_4154649_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000001526 81.0
PYH2_k127_4219567_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 8.274e-219 680.0
PYH2_k127_4219567_1 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 358.0
PYH2_k127_4219567_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
PYH2_k127_4263668_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 8.811e-297 920.0
PYH2_k127_4263668_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.458e-196 614.0
PYH2_k127_4263668_2 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000002222 99.0
PYH2_k127_4263668_3 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02456 - - 0.000000000000000000008151 95.0
PYH2_k127_4274256_0 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 307.0
PYH2_k127_4274256_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006922 270.0
PYH2_k127_4274256_3 - - - - 0.00000000000000000000000000000000000000000000000000000004204 201.0
PYH2_k127_4274256_4 - - - - 0.000000000000000000000000000000000000000000008311 164.0
PYH2_k127_4274256_5 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000002597 154.0
PYH2_k127_429146_0 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 451.0
PYH2_k127_429146_1 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 446.0
PYH2_k127_429146_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
PYH2_k127_429146_3 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
PYH2_k127_429146_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000007922 158.0
PYH2_k127_429146_5 Histidine kinase K07645 - 2.7.13.3 0.00000000000000000000000000000000000001504 160.0
PYH2_k127_4303305_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.16e-295 909.0
PYH2_k127_4303305_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.517e-272 846.0
PYH2_k127_4303305_2 apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 601.0
PYH2_k127_4303305_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 552.0
PYH2_k127_4303305_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 385.0
PYH2_k127_4303305_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000001964 135.0
PYH2_k127_4303305_6 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000006154 98.0
PYH2_k127_431447_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1996.0
PYH2_k127_431447_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1276.0
PYH2_k127_431447_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000481 219.0
PYH2_k127_431447_11 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000001412 213.0
PYH2_k127_431447_12 Histidine kinase - - - 0.000000000000000000001333 99.0
PYH2_k127_431447_13 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 0.000000000000007518 74.0
PYH2_k127_431447_14 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000002482 61.0
PYH2_k127_431447_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 564.0
PYH2_k127_431447_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 531.0
PYH2_k127_431447_4 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 528.0
PYH2_k127_431447_5 leucine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 371.0
PYH2_k127_431447_6 Four helix bundle sensory module for signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 347.0
PYH2_k127_431447_7 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 328.0
PYH2_k127_431447_8 Ferritin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 284.0
PYH2_k127_431447_9 Histidine kinase K03413,K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005894 274.0
PYH2_k127_4316256_0 Glycosyltransferase like family 2 K20444 - - 3.983e-237 762.0
PYH2_k127_4316256_1 Bacterial sugar transferase K00996 - 2.7.8.6 1.494e-205 647.0
PYH2_k127_4316256_10 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000702 160.0
PYH2_k127_4316256_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00001259 57.0
PYH2_k127_4316256_13 - - - - 0.0003438 43.0
PYH2_k127_4316256_2 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 468.0
PYH2_k127_4316256_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 435.0
PYH2_k127_4316256_4 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 432.0
PYH2_k127_4316256_5 Glycosyl transferase, family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 332.0
PYH2_k127_4316256_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006859 240.0
PYH2_k127_4316256_7 ABC-2 type transporter K09688,K09690,K09692 - - 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
PYH2_k127_4316256_8 group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
PYH2_k127_4316256_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000006222 219.0
PYH2_k127_44119_0 ATP-binding protein K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 436.0
PYH2_k127_44119_1 ABC transporter permease K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 366.0
PYH2_k127_44119_2 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000005278 187.0
PYH2_k127_44119_3 - - - - 0.00000000000000000000000000000004376 127.0
PYH2_k127_4482977_0 Methyltransferase, chemotaxis proteins K13924 - 2.1.1.80,3.1.1.61 8.239e-259 809.0
PYH2_k127_4482977_1 Small Multidrug Resistance protein K03297,K11741 - - 0.00000000000000000000000000000000000008653 144.0
PYH2_k127_4482977_2 PAS fold K03776 - - 0.0000000000000000000003512 100.0
PYH2_k127_4482977_3 Protein of unknown function (DUF2860) - - - 0.00006518 54.0
PYH2_k127_453721_0 Type I secretion system ATPase K12541 - - 0.0 1151.0
PYH2_k127_453721_1 Outer membrane efflux protein K12543 - - 1.836e-236 739.0
PYH2_k127_453721_2 HlyD membrane-fusion protein of T1SS K12542 - - 3.549e-229 715.0
PYH2_k127_453721_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000107 241.0
PYH2_k127_453721_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000002053 170.0
PYH2_k127_453721_5 Belongs to the ompA family K03286 - - 0.000000000000000000000000000001644 125.0
PYH2_k127_4676707_0 DNA helicase K03657 - 3.6.4.12 0.0 1258.0
PYH2_k127_4676707_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000003242 138.0
PYH2_k127_4708623_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1247.0
PYH2_k127_4708623_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1146.0
PYH2_k127_4708623_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 338.0
PYH2_k127_4708623_11 phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 318.0
PYH2_k127_4708623_12 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 298.0
PYH2_k127_4708623_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH2_k127_4708623_14 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000001863 150.0
PYH2_k127_4708623_15 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000001041 119.0
PYH2_k127_4708623_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.931e-211 659.0
PYH2_k127_4708623_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 588.0
PYH2_k127_4708623_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
PYH2_k127_4708623_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 458.0
PYH2_k127_4708623_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 377.0
PYH2_k127_4708623_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
PYH2_k127_4708623_8 Nucleoside-specific channel-forming protein, Tsx - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 353.0
PYH2_k127_4708623_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 328.0
PYH2_k127_4741088_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 0.0 1061.0
PYH2_k127_4741088_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.716e-267 832.0
PYH2_k127_4741088_10 - - - - 0.000000000000000000000000000000000000000000007667 169.0
PYH2_k127_4741088_11 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000001134 153.0
PYH2_k127_4741088_12 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000000000009529 141.0
PYH2_k127_4741088_13 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000009329 143.0
PYH2_k127_4741088_15 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000001144 129.0
PYH2_k127_4741088_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000001271 66.0
PYH2_k127_4741088_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 1.563e-203 635.0
PYH2_k127_4741088_3 Major Facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 553.0
PYH2_k127_4741088_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 544.0
PYH2_k127_4741088_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 511.0
PYH2_k127_4741088_6 Archaea bacterial proteins of unknown function K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 434.0
PYH2_k127_4741088_7 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 430.0
PYH2_k127_4741088_8 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
PYH2_k127_4741088_9 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
PYH2_k127_4788615_0 Abc transporter K02035 - - 1.383e-272 844.0
PYH2_k127_4788615_1 COG1070 Sugar (pentulose and hexulose) K11216 - 2.7.1.189 9.972e-262 812.0
PYH2_k127_4788615_10 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004899 270.0
PYH2_k127_4788615_11 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
PYH2_k127_4788615_12 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001595 244.0
PYH2_k127_4788615_13 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 230.0
PYH2_k127_4788615_14 - - - - 0.00000000000000000000000000000000000000000000000000006914 190.0
PYH2_k127_4788615_15 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000000004481 186.0
PYH2_k127_4788615_16 - - - - 0.000000000000000000000000000000000000000000001461 166.0
PYH2_k127_4788615_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 1.796e-235 732.0
PYH2_k127_4788615_3 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 5.7e-201 626.0
PYH2_k127_4788615_4 Class II Aldolase and Adducin N-terminal domain - - - 1.037e-198 624.0
PYH2_k127_4788615_5 carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 392.0
PYH2_k127_4788615_6 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 391.0
PYH2_k127_4788615_7 Sulfatase K03760 - 2.7.8.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 373.0
PYH2_k127_4788615_8 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 354.0
PYH2_k127_4788615_9 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 316.0
PYH2_k127_480176_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.069e-248 773.0
PYH2_k127_480176_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 5.026e-228 711.0
PYH2_k127_480176_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.571e-211 658.0
PYH2_k127_480176_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 567.0
PYH2_k127_480176_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 505.0
PYH2_k127_480176_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000008542 183.0
PYH2_k127_480176_6 - - - - 0.00000000000000000000000000000000000000000000000002917 182.0
PYH2_k127_480176_7 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000001561 154.0
PYH2_k127_4818377_0 Sugar (and other) transporter - - - 5.187e-202 635.0
PYH2_k127_4818377_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 507.0
PYH2_k127_4818377_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 404.0
PYH2_k127_4818377_3 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 304.0
PYH2_k127_4818377_4 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
PYH2_k127_4818377_5 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000009497 210.0
PYH2_k127_4818377_6 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000002511 148.0
PYH2_k127_4845941_0 Oligosaccharyl transferase, STT3 subunit K07151,K17251 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046872,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.99.18,2.4.99.19 1.345e-311 968.0
PYH2_k127_4845941_1 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 1.808e-242 762.0
PYH2_k127_4845941_2 Belongs to the DegT DnrJ EryC1 family K15910 - 2.6.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 600.0
PYH2_k127_4845941_3 hmm pf00534 K15914 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.290 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 550.0
PYH2_k127_4845941_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 349.0
PYH2_k127_4845941_5 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 334.0
PYH2_k127_4845941_6 Transferase K15915 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 292.0
PYH2_k127_4845941_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000003826 222.0
PYH2_k127_4845941_8 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K15913 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.3.1.203 0.0000000000000000000000000000000000000000000000000001085 193.0
PYH2_k127_4845941_9 Diguanylate cyclase - - - 0.00000000000000007997 82.0
PYH2_k127_4853638_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 6.579e-316 974.0
PYH2_k127_4853638_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.873e-276 852.0
PYH2_k127_4853638_10 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000003687 200.0
PYH2_k127_4853638_11 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000004451 137.0
PYH2_k127_4853638_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 387.0
PYH2_k127_4853638_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 379.0
PYH2_k127_4853638_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 355.0
PYH2_k127_4853638_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
PYH2_k127_4853638_6 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
PYH2_k127_4853638_7 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 251.0
PYH2_k127_4853638_8 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000177 246.0
PYH2_k127_4853638_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
PYH2_k127_4860166_0 Glycerol-3-phosphate dehydrogenase K11473 - - 1.922e-259 801.0
PYH2_k127_4860166_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 535.0
PYH2_k127_4860166_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 497.0
PYH2_k127_4860166_3 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000006467 205.0
PYH2_k127_4860166_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000006224 112.0
PYH2_k127_4860166_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000002053 106.0
PYH2_k127_4860469_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 537.0
PYH2_k127_4860469_1 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 460.0
PYH2_k127_4860469_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 378.0
PYH2_k127_4860469_3 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000000000000003397 203.0
PYH2_k127_4860469_4 beta-lactamase activity K01058,K07126,K12543 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000009025 194.0
PYH2_k127_4860469_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000002814 144.0
PYH2_k127_4875588_0 TonB-dependent receptor - - - 8.918e-259 815.0
PYH2_k127_4875588_1 Belongs to the DEAD box helicase family - - - 2.291e-211 663.0
PYH2_k127_4875588_2 EAL domain - - - 3.759e-197 621.0
PYH2_k127_4875588_3 DNA RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 355.0
PYH2_k127_4875588_4 modulator of drug activity K03923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 333.0
PYH2_k127_4875588_5 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 287.0
PYH2_k127_4875588_6 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
PYH2_k127_4875588_7 - - - - 0.000000000000000000000000000005924 120.0
PYH2_k127_4878196_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 4.635e-262 814.0
PYH2_k127_4878196_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.363e-241 755.0
PYH2_k127_4878196_2 COGs COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 368.0
PYH2_k127_4878196_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000281 272.0
PYH2_k127_4901744_0 ABC transporter K11085 - - 7.689e-287 889.0
PYH2_k127_4901744_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.184e-243 755.0
PYH2_k127_4901744_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 2.021e-205 642.0
PYH2_k127_4948234_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1288.0
PYH2_k127_4948234_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 9.989e-253 785.0
PYH2_k127_4948234_10 Cytochrome oxidase maturation protein - - - 0.000000000000000000000000002904 111.0
PYH2_k127_4948234_2 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 3.377e-199 622.0
PYH2_k127_4948234_3 heptosyltransferase ii K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 575.0
PYH2_k127_4948234_4 lipopolysaccharide core region biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 542.0
PYH2_k127_4948234_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 435.0
PYH2_k127_4948234_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 359.0
PYH2_k127_4948234_7 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008349 278.0
PYH2_k127_4948234_8 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000008119 162.0
PYH2_k127_4948234_9 Cytochrome c553 K08738 - - 0.000000000000000000000000000000000000000001202 158.0
PYH2_k127_4985506_0 Major facilitator superfamily K03762 - - 1.944e-199 629.0
PYH2_k127_4985506_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 7.251e-198 619.0
PYH2_k127_4985506_2 flagellar motor switch protein K02416 - - 3.074e-195 612.0
PYH2_k127_4985506_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 472.0
PYH2_k127_4985506_4 flagellar motor switch protein K02417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 409.0
PYH2_k127_4985506_5 penicillin-binding protein K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 406.0
PYH2_k127_4985506_6 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 379.0
PYH2_k127_4985506_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000001496 197.0
PYH2_k127_4985506_8 - - - - 0.0000000000000000000000000000000000000000003157 159.0
PYH2_k127_4985506_9 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000003225 126.0
PYH2_k127_501873_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.768e-196 614.0
PYH2_k127_501873_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 454.0
PYH2_k127_501873_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 344.0
PYH2_k127_501873_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003054 246.0
PYH2_k127_501873_4 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000175 100.0
PYH2_k127_5032647_0 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.0 1107.0
PYH2_k127_5032647_1 Response regulator receiver K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 529.0
PYH2_k127_5032647_2 molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 406.0
PYH2_k127_5032647_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 352.0
PYH2_k127_5032647_4 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 249.0
PYH2_k127_5032647_5 - - - - 0.000000000000000000000000000000000000000002836 156.0
PYH2_k127_5032647_6 - - - - 0.000000000000000000000000000000000000000261 155.0
PYH2_k127_5034876_0 MgtC family - - - 8.803e-207 651.0
PYH2_k127_5034876_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 597.0
PYH2_k127_5034876_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 480.0
PYH2_k127_5034876_3 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 404.0
PYH2_k127_5034876_4 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 347.0
PYH2_k127_5103942_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 1.037e-302 934.0
PYH2_k127_5103942_1 COG1450 Type II secretory pathway component PulD K02453 - - 8.129e-236 739.0
PYH2_k127_5103942_2 COG1459 Type II secretory pathway, component PulF K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 515.0
PYH2_k127_5103942_3 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 361.0
PYH2_k127_5103942_5 Pilus assembly protein - - - 0.000000000000000000000000000000000000000001119 158.0
PYH2_k127_5103942_7 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000003709 134.0
PYH2_k127_526477_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 1.521e-235 733.0
PYH2_k127_526477_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006195 249.0
PYH2_k127_526477_2 Transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000000000008905 169.0
PYH2_k127_526477_3 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000007834 168.0
PYH2_k127_526477_4 permease K07089 - - 0.00000000000000000000007406 98.0
PYH2_k127_536077_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1031.0
PYH2_k127_536077_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 471.0
PYH2_k127_536077_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003102 226.0
PYH2_k127_536077_3 peptidyl-prolyl K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000004629 165.0
PYH2_k127_5517343_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 601.0
PYH2_k127_5517343_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 435.0
PYH2_k127_5517343_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 419.0
PYH2_k127_5517343_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 355.0
PYH2_k127_5517343_4 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004751 230.0
PYH2_k127_5517343_6 Belongs to the 'phage' integrase family K14059 - - 0.000000000000000000000000006572 117.0
PYH2_k127_5618855_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.728e-240 772.0
PYH2_k127_5618855_1 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 5.859e-233 723.0
PYH2_k127_5618855_10 - - - - 0.000000000000000000000000000000000000000000000001602 188.0
PYH2_k127_5618855_11 - - - - 0.000000000000000000000000000005503 124.0
PYH2_k127_5618855_12 Helix-turn-helix domain - - - 0.00000000000000000000000000001179 122.0
PYH2_k127_5618855_13 MORN repeat variant - - - 0.0000006305 55.0
PYH2_k127_5618855_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 6.908e-211 658.0
PYH2_k127_5618855_3 Flagellar Assembly Protein A - - - 4.891e-210 668.0
PYH2_k127_5618855_4 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 606.0
PYH2_k127_5618855_5 PFAM HI0933 family protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 567.0
PYH2_k127_5618855_6 phosphorelay sensor kinase activity K01768,K07673,K07713 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 441.0
PYH2_k127_5618855_7 - catabolite gene activator and regulatory subunit of cAMP-dependent protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 294.0
PYH2_k127_5618855_8 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 302.0
PYH2_k127_5618855_9 GTP-binding protein K06207 - - 0.000000000000000000000000000000000000000000000000008851 180.0
PYH2_k127_5622882_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1210.0
PYH2_k127_5622882_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 606.0
PYH2_k127_5622882_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 374.0
PYH2_k127_5622882_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
PYH2_k127_5622882_4 - - - - 0.0000000000000000000000000000000000000000000000000000000001114 207.0
PYH2_k127_5629266_0 twitching motility protein K02669 - - 5.143e-217 677.0
PYH2_k127_5629266_1 Domain of unknown function (DUF4105) - - - 1.762e-207 651.0
PYH2_k127_5629266_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 501.0
PYH2_k127_5629266_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000197 246.0
PYH2_k127_5681872_0 HAMP domain - - - 6.706e-316 978.0
PYH2_k127_5681872_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 541.0
PYH2_k127_5681872_10 P-type atpase K17686 - 3.6.3.54 0.00000007109 57.0
PYH2_k127_5681872_2 Arginosuccinate synthase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 530.0
PYH2_k127_5681872_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
PYH2_k127_5681872_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 234.0
PYH2_k127_5681872_5 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001973 231.0
PYH2_k127_5681872_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000003903 194.0
PYH2_k127_5681872_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000003694 173.0
PYH2_k127_5681872_8 - - - - 0.0000000000000000000000000000000001147 136.0
PYH2_k127_5726691_0 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 606.0
PYH2_k127_5726691_1 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 326.0
PYH2_k127_5726691_2 MiaB-like tRNA modifying enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 296.0
PYH2_k127_5726691_3 outer membrane porin, OprD family - - - 0.000000000000002667 82.0
PYH2_k127_5734826_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1125.0
PYH2_k127_5734826_1 COG0457 FOG TPR repeat - - - 2.043e-314 980.0
PYH2_k127_5734826_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 361.0
PYH2_k127_5734826_11 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 301.0
PYH2_k127_5734826_12 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001389 245.0
PYH2_k127_5734826_13 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000773 196.0
PYH2_k127_5734826_14 - - - - 0.00000000000001139 73.0
PYH2_k127_5734826_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.083e-230 716.0
PYH2_k127_5734826_3 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 524.0
PYH2_k127_5734826_4 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 505.0
PYH2_k127_5734826_5 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 482.0
PYH2_k127_5734826_6 lipopolysaccharide heptosyltransferase K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 473.0
PYH2_k127_5734826_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 441.0
PYH2_k127_5734826_8 PFAM dUTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 398.0
PYH2_k127_5734826_9 lipid a biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 398.0
PYH2_k127_5857140_0 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 511.0
PYH2_k127_5857140_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
PYH2_k127_5857140_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000004835 164.0
PYH2_k127_5857140_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000904 77.0
PYH2_k127_5889014_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 8.914e-234 726.0
PYH2_k127_5889014_1 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 282.0
PYH2_k127_5889014_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001368 273.0
PYH2_k127_5889014_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000009247 73.0
PYH2_k127_5911961_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1356.0
PYH2_k127_5911961_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 460.0
PYH2_k127_5911961_2 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000000000000000000006612 220.0
PYH2_k127_6058487_0 abc transporter atp-binding protein K06147,K06148 - - 2.507e-296 917.0
PYH2_k127_6058487_1 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 387.0
PYH2_k127_6058487_2 acid membrane antigen A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 374.0
PYH2_k127_6058487_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001234 259.0
PYH2_k127_6058487_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000001187 145.0
PYH2_k127_60729_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.586e-251 779.0
PYH2_k127_60729_1 Participates in both transcription termination and antitermination K02600 - - 8.654e-205 641.0
PYH2_k127_60729_10 Receptor - - - 0.000000000000000000000000000001645 123.0
PYH2_k127_60729_2 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 534.0
PYH2_k127_60729_3 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
PYH2_k127_60729_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
PYH2_k127_60729_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 290.0
PYH2_k127_60729_6 protein conserved in bacteria K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 256.0
PYH2_k127_60729_7 PFAM Fimbrial assembly family protein - - - 0.00000000000000000000000000000000000000000000000000000000000007834 217.0
PYH2_k127_60729_8 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
PYH2_k127_60729_9 - - - - 0.0000000000000000000000000000000000000003977 149.0
PYH2_k127_6107450_0 chemotaxis protein - - - 1.196e-237 750.0
PYH2_k127_6107450_1 Sulfatase-modifying factor enzyme 1 - - - 2.566e-210 661.0
PYH2_k127_6107450_2 Aminotransferase, class I K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 561.0
PYH2_k127_6107450_3 cofactor binding K09979 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH2_k127_6107450_4 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000001872 181.0
PYH2_k127_6107450_5 - - - - 0.00000000000000002839 82.0
PYH2_k127_6119543_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 566.0
PYH2_k127_6119543_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 340.0
PYH2_k127_6119543_2 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000003762 186.0
PYH2_k127_6119543_4 flagellar - - - 0.0004132 44.0
PYH2_k127_6241280_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 3.631e-275 850.0
PYH2_k127_6241280_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.839e-210 655.0
PYH2_k127_6241280_2 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 571.0
PYH2_k127_6319894_0 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 490.0
PYH2_k127_6319894_1 Dtw domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 305.0
PYH2_k127_6319894_2 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000003635 184.0
PYH2_k127_6319894_3 diguanylate cyclase K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000008503 172.0
PYH2_k127_6319894_4 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000006463 113.0
PYH2_k127_6319894_6 Outer membrane protein beta-barrel family K02014 - - 0.0000007855 53.0
PYH2_k127_6363193_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1545.0
PYH2_k127_6363193_1 Ammonium Transporter K03320 - - 2.76e-231 721.0
PYH2_k127_6363193_2 Ammonium Transporter K03320 - - 9.056e-215 670.0
PYH2_k127_6363193_3 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 1.919e-204 639.0
PYH2_k127_6363193_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.816e-204 637.0
PYH2_k127_6363193_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 592.0
PYH2_k127_6363193_6 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009314 242.0
PYH2_k127_6363193_7 (Lipo)protein K09860 - - 0.0000000000000000000000000000000000000000000000000000000000002415 214.0
PYH2_k127_6363193_8 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000002955 212.0
PYH2_k127_65753_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 539.0
PYH2_k127_65753_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 402.0
PYH2_k127_65753_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 344.0
PYH2_k127_65753_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
PYH2_k127_65753_4 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 336.0
PYH2_k127_65753_5 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 287.0
PYH2_k127_65753_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004142 262.0
PYH2_k127_65753_7 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000846 122.0
PYH2_k127_65753_8 Endoribonuclease that initiates mRNA decay K18682 - - 0.000002384 55.0
PYH2_k127_6575581_0 Histidine kinase - - - 0.0 1213.0
PYH2_k127_6575581_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.017e-286 888.0
PYH2_k127_6575581_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 510.0
PYH2_k127_6575581_3 general secretion pathway protein K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 426.0
PYH2_k127_6575581_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
PYH2_k127_6575581_5 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000005943 211.0
PYH2_k127_6575581_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000002355 205.0
PYH2_k127_6575581_8 - - - - 0.00001653 53.0
PYH2_k127_6598622_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 330.0
PYH2_k127_6598622_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000847 205.0
PYH2_k127_6598622_2 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.00000000000000000000000000000000000000000000000000000008114 196.0
PYH2_k127_6598622_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000003461 173.0
PYH2_k127_6598622_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000000000001201 170.0
PYH2_k127_6598622_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000002036 85.0
PYH2_k127_6615161_0 anthranilate synthase component K01657 - 4.1.3.27 1.267e-239 747.0
PYH2_k127_6615161_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 389.0
PYH2_k127_6615161_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
PYH2_k127_6615161_3 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000001483 160.0
PYH2_k127_6635932_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.152e-260 805.0
PYH2_k127_6635932_1 Pilus assembly protein - - - 3.707e-244 762.0
PYH2_k127_6635932_10 flagellar protein FliS K02422 - - 0.000006792 48.0
PYH2_k127_6635932_2 C-terminal domain of metallo-carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 557.0
PYH2_k127_6635932_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 540.0
PYH2_k127_6635932_4 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 443.0
PYH2_k127_6635932_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 313.0
PYH2_k127_6635932_6 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 318.0
PYH2_k127_6635932_7 - - - - 0.00000000000000000000000000000000000000000000000003356 184.0
PYH2_k127_6635932_8 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000003713 157.0
PYH2_k127_6635932_9 - - - - 0.00000000000000000003041 93.0
PYH2_k127_6637824_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 525.0
PYH2_k127_6637824_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 524.0
PYH2_k127_6637824_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 359.0
PYH2_k127_6637824_3 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 284.0
PYH2_k127_6637824_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000002346 258.0
PYH2_k127_6637824_5 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000000000000000000000000005167 197.0
PYH2_k127_6644611_0 abc transporter atp-binding protein - - - 0.0 1006.0
PYH2_k127_6644611_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 5.121e-235 732.0
PYH2_k127_6644611_11 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000003376 193.0
PYH2_k127_6644611_13 RNA-binding protein - - - 0.000000000000000000000000000000000000000000000001298 174.0
PYH2_k127_6644611_14 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000006033 168.0
PYH2_k127_6644611_15 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000002529 147.0
PYH2_k127_6644611_16 S4 domain K14761 - - 0.0000000000000000000000006944 106.0
PYH2_k127_6644611_17 Protein of unknown function (DUF1653) - - - 0.0000000000000000000003444 97.0
PYH2_k127_6644611_2 Potassium uptake protein K03498 - - 2.177e-220 689.0
PYH2_k127_6644611_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 485.0
PYH2_k127_6644611_4 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
PYH2_k127_6644611_5 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 453.0
PYH2_k127_6644611_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 412.0
PYH2_k127_6644611_7 uptake protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 358.0
PYH2_k127_6644611_8 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 354.0
PYH2_k127_6644611_9 protein of Gammaproteobacteria UniRef RepID - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 298.0
PYH2_k127_6652617_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1090.0
PYH2_k127_6652617_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 6.355e-249 772.0
PYH2_k127_6652617_10 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005562 274.0
PYH2_k127_6652617_11 - - - - 0.000000000000000000000000000000000000000000000000008043 187.0
PYH2_k127_6652617_12 energy transducer activity K03832 - - 0.0000000000000000000000000000000000008689 147.0
PYH2_k127_6652617_13 - - - - 0.000000000000000000000000000000006358 131.0
PYH2_k127_6652617_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000001045 123.0
PYH2_k127_6652617_15 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000007858 108.0
PYH2_k127_6652617_16 - - - - 0.00000000000000000003779 92.0
PYH2_k127_6652617_17 COG0841 Cation multidrug efflux pump - - - 0.000000000000005082 76.0
PYH2_k127_6652617_18 Flagellar hook protein flgE - - - 0.00000013 53.0
PYH2_k127_6652617_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 9.551e-214 666.0
PYH2_k127_6652617_3 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 562.0
PYH2_k127_6652617_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 490.0
PYH2_k127_6652617_5 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 486.0
PYH2_k127_6652617_6 flagellar basal body K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 453.0
PYH2_k127_6652617_7 phage repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 415.0
PYH2_k127_6652617_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 367.0
PYH2_k127_6652617_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 308.0
PYH2_k127_6663495_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 5.746e-200 631.0
PYH2_k127_6663495_1 -Amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 567.0
PYH2_k127_6663495_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 539.0
PYH2_k127_6663495_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 498.0
PYH2_k127_6663495_4 Two-component sensor histidine kinase response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 462.0
PYH2_k127_6663495_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 305.0
PYH2_k127_6663495_6 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 299.0
PYH2_k127_6663495_9 Histidine kinase - - - 0.000003514 54.0
PYH2_k127_6667048_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 9.96e-258 796.0
PYH2_k127_6667048_1 Cytochrome c oxidase accessory protein - - - 9.42e-247 769.0
PYH2_k127_6667048_10 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 327.0
PYH2_k127_6667048_11 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 314.0
PYH2_k127_6667048_12 PFAM Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 286.0
PYH2_k127_6667048_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001227 263.0
PYH2_k127_6667048_14 Haem-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005014 251.0
PYH2_k127_6667048_15 AMIN domain - - - 0.0000000000000000000000000000000000000000000000000000001418 200.0
PYH2_k127_6667048_16 Flagellar biosynthetic protein FliQ K02420 - - 0.0000000000000000000000000000000000000000001609 159.0
PYH2_k127_6667048_17 - - - - 0.00000000000000000000002507 102.0
PYH2_k127_6667048_18 - - - - 0.0000000000000000002629 88.0
PYH2_k127_6667048_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 6.944e-203 634.0
PYH2_k127_6667048_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 9.561e-198 619.0
PYH2_k127_6667048_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 509.0
PYH2_k127_6667048_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 507.0
PYH2_k127_6667048_6 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 498.0
PYH2_k127_6667048_7 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 436.0
PYH2_k127_6667048_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 368.0
PYH2_k127_6667048_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 336.0
PYH2_k127_6667610_0 Histidine kinase K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 376.0
PYH2_k127_6667610_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 318.0
PYH2_k127_6676477_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 7.673e-242 756.0
PYH2_k127_6676477_1 RNA-binding protein homologous to eukaryotic snRNP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 556.0
PYH2_k127_6676477_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 413.0
PYH2_k127_6676477_3 - - - - 0.0000000000000000000000000000000002042 134.0
PYH2_k127_6676477_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000272 47.0
PYH2_k127_6679829_0 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 394.0
PYH2_k127_6679829_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 373.0
PYH2_k127_6679829_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 321.0
PYH2_k127_6679829_3 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 289.0
PYH2_k127_6679829_4 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000004262 142.0
PYH2_k127_6687302_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1456.0
PYH2_k127_6687302_1 Phospholipid glycerol acyltransferase - - - 1.471e-301 932.0
PYH2_k127_6687302_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 608.0
PYH2_k127_6687302_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 597.0
PYH2_k127_6687302_4 (EAL) domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 491.0
PYH2_k127_6687302_5 Pseudouridine synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 457.0
PYH2_k127_6687302_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 317.0
PYH2_k127_6687302_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 284.0
PYH2_k127_6687302_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000002666 101.0
PYH2_k127_6705552_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.671e-218 679.0
PYH2_k127_6705552_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 1.384e-211 659.0
PYH2_k127_6705552_10 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 445.0
PYH2_k127_6705552_11 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 388.0
PYH2_k127_6705552_12 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 363.0
PYH2_k127_6705552_13 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 364.0
PYH2_k127_6705552_14 PFAM O-Antigen K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 368.0
PYH2_k127_6705552_15 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000189 126.0
PYH2_k127_6705552_16 protein conserved in bacteria K09824 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 0.000000000000000000000000005088 119.0
PYH2_k127_6705552_17 - - - - 0.000000000005378 77.0
PYH2_k127_6705552_2 Alginate O-acetylation protein - - - 2.173e-207 655.0
PYH2_k127_6705552_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 574.0
PYH2_k127_6705552_4 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 543.0
PYH2_k127_6705552_5 Glycosyl transferases group 1 K17249 - 2.4.1.292 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 529.0
PYH2_k127_6705552_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 498.0
PYH2_k127_6705552_7 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 482.0
PYH2_k127_6705552_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 470.0
PYH2_k127_6705552_9 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 467.0
PYH2_k127_6716388_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 5.527e-230 715.0
PYH2_k127_6716388_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 359.0
PYH2_k127_6716388_2 ABC transporter, ATP-binding protein K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 290.0
PYH2_k127_6716388_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000001411 78.0
PYH2_k127_6748704_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 1.165e-283 876.0
PYH2_k127_6748704_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 313.0
PYH2_k127_6748704_2 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000002923 182.0
PYH2_k127_6778297_0 STAS domain K03321 - - 0.0 1065.0
PYH2_k127_6778297_1 Highly conserved protein containing a thioredoxin domain K06888 - - 8.53e-295 917.0
PYH2_k127_6778297_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
PYH2_k127_6778297_11 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
PYH2_k127_6778297_12 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005197 254.0
PYH2_k127_6778297_13 Helix-turn-helix domain K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000002606 235.0
PYH2_k127_6778297_14 - - - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
PYH2_k127_6778297_15 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000000000000000000000001221 190.0
PYH2_k127_6778297_16 Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000003981 162.0
PYH2_k127_6778297_17 Sulfur oxidation protein SoxY - - - 0.0000000000000000000000000000000000001878 148.0
PYH2_k127_6778297_18 cytochrome c class I - - - 0.000000000000000000000000000000006981 134.0
PYH2_k127_6778297_19 superoxide reductase activity K05919,K17227 - 1.15.1.2 0.000000000000000004298 87.0
PYH2_k127_6778297_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 9.771e-278 865.0
PYH2_k127_6778297_3 Pyridine nucleotide-disulphide oxidoreductase K17229 - 1.8.2.3 6.864e-271 838.0
PYH2_k127_6778297_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 606.0
PYH2_k127_6778297_5 threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 579.0
PYH2_k127_6778297_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 552.0
PYH2_k127_6778297_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 522.0
PYH2_k127_6778297_8 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 466.0
PYH2_k127_6778297_9 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 425.0
PYH2_k127_6783347_0 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1303.0
PYH2_k127_6783347_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 1.306e-258 801.0
PYH2_k127_6783347_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.308e-218 678.0
PYH2_k127_6783347_3 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.0000000000000000000000000000004607 123.0
PYH2_k127_6787974_0 Histidine kinase A domain protein K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 353.0
PYH2_k127_6787974_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000001071 84.0
PYH2_k127_6821373_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 3.424e-277 859.0
PYH2_k127_6821373_1 COG0842 ABC-type multidrug transport system, permease component K01992 - - 2.476e-200 629.0
PYH2_k127_6821373_10 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000003175 93.0
PYH2_k127_6821373_2 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 533.0
PYH2_k127_6821373_3 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 431.0
PYH2_k127_6821373_4 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
PYH2_k127_6821373_5 PFAM Polysaccharide deacetylase K14659,K22278 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
PYH2_k127_6821373_6 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 353.0
PYH2_k127_6821373_7 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 335.0
PYH2_k127_6821373_8 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 329.0
PYH2_k127_6821373_9 - - - - 0.000000000000000000001947 95.0
PYH2_k127_6837722_0 Domain of Unknown Function (DUF748) - - - 0.0 1180.0
PYH2_k127_6837722_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 8.217e-195 608.0
PYH2_k127_6837722_2 Belongs to the UPF0324 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 299.0
PYH2_k127_6856269_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 381.0
PYH2_k127_6856269_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 373.0
PYH2_k127_6856269_2 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 340.0
PYH2_k127_6863915_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 7.206e-247 767.0
PYH2_k127_6863915_1 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
PYH2_k127_6863915_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000003962 134.0
PYH2_k127_6869591_0 ATPase (AAA - - - 0.0 1047.0
PYH2_k127_6869591_1 COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 4.454e-206 645.0
PYH2_k127_6869591_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 9.508e-196 618.0
PYH2_k127_6869591_3 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 601.0
PYH2_k127_6869591_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 518.0
PYH2_k127_6869591_5 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 478.0
PYH2_k127_6869591_6 DnaJ domain protein K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 426.0
PYH2_k127_6869591_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002507 200.0
PYH2_k127_6869591_8 - - - - 0.00000000000000000000000000000000000001122 150.0
PYH2_k127_6885546_0 chemotaxis protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 554.0
PYH2_k127_6885546_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 363.0
PYH2_k127_6885546_2 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000003522 245.0
PYH2_k127_6885546_3 chemotaxis K03408 - - 0.00000000000000000000000000007331 121.0
PYH2_k127_6885546_5 chemotaxis K03408 - - 0.00000000000000000003784 95.0
PYH2_k127_6887453_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.271e-220 688.0
PYH2_k127_6887453_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 364.0
PYH2_k127_6887453_2 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 323.0
PYH2_k127_6887453_3 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000001621 218.0
PYH2_k127_6887453_4 TIGRFAM cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000003797 97.0
PYH2_k127_6941374_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 5.676e-237 737.0
PYH2_k127_6941374_1 chemotaxis protein K03406 - - 1.19e-228 718.0
PYH2_k127_6941374_2 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 451.0
PYH2_k127_6941374_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
PYH2_k127_6941374_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000008597 220.0
PYH2_k127_6941374_5 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000001623 183.0
PYH2_k127_6941374_6 Cupin domain K11312 - - 0.00000000000000001497 85.0
PYH2_k127_6965929_0 TonB dependent receptor K02014 - - 1.456e-312 970.0
PYH2_k127_6965929_1 Glycolate oxidase subunit K00104 - 1.1.3.15 7.947e-280 862.0
PYH2_k127_6965929_2 peptidase M23 - - - 6.381e-200 628.0
PYH2_k127_6965929_3 Belongs to the agmatine deiminase family - - - 5.599e-194 607.0
PYH2_k127_6965929_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 516.0
PYH2_k127_6965929_5 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 356.0
PYH2_k127_6965929_6 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 344.0
PYH2_k127_6988771_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.742e-237 736.0
PYH2_k127_6988771_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 558.0
PYH2_k127_6988771_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000003612 164.0
PYH2_k127_6988771_11 Rod binding protein - - - 0.000000000000000000000000000000000000000000006634 164.0
PYH2_k127_6988771_12 Anti-sigma-28 factor, FlgM - - - 0.0000000000000000000000000009203 113.0
PYH2_k127_6988771_2 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 348.0
PYH2_k127_6988771_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 316.0
PYH2_k127_6988771_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 310.0
PYH2_k127_6988771_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009182 276.0
PYH2_k127_6988771_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003848 233.0
PYH2_k127_6988771_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000000000003537 228.0
PYH2_k127_6988771_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000001593 214.0
PYH2_k127_6988771_9 flagellar hook-associated protein K02396 - - 0.0000000000000000000000000000000000000000000001339 171.0
PYH2_k127_7007176_0 ATP-dependent DNA helicase K03655 - 3.6.4.12 9.907e-295 914.0
PYH2_k127_7007176_1 Peptidase, M16 - - - 8.282e-209 655.0
PYH2_k127_7007176_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000007975 133.0
PYH2_k127_7007176_3 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000003964 81.0
PYH2_k127_7048567_0 Histidine kinase-like ATPases K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 548.0
PYH2_k127_7048567_1 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000001239 167.0
PYH2_k127_7048567_2 Diguanylate cyclase - - - 0.000000000000000000001289 94.0
PYH2_k127_7049610_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 3.12e-202 633.0
PYH2_k127_7049610_1 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000004726 256.0
PYH2_k127_7049610_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000001686 143.0
PYH2_k127_7050733_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 5.496e-252 779.0
PYH2_k127_7050733_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 546.0
PYH2_k127_7050733_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 319.0
PYH2_k127_7050733_3 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000001949 203.0
PYH2_k127_7050733_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000000000000002018 180.0
PYH2_k127_7209334_0 Belongs to the TtcA family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 468.0
PYH2_k127_7209334_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 382.0
PYH2_k127_7209334_2 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 312.0
PYH2_k127_7209334_3 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 284.0
PYH2_k127_7209334_4 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000015 151.0
PYH2_k127_7384678_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.86e-234 727.0
PYH2_k127_7384678_1 UDP-N-acetylglucosamine 4,6-dehydratase K15894 - 4.2.1.115 2.604e-201 628.0
PYH2_k127_7384678_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 354.0
PYH2_k127_7384678_11 ribosomal protein L3 K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 355.0
PYH2_k127_7384678_12 pseudaminic acid biosynthesis-associated protein PseG K15897 - 3.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
PYH2_k127_7384678_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 303.0
PYH2_k127_7384678_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 305.0
PYH2_k127_7384678_15 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 288.0
PYH2_k127_7384678_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
PYH2_k127_7384678_17 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
PYH2_k127_7384678_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001046 243.0
PYH2_k127_7384678_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000007948 234.0
PYH2_k127_7384678_2 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 594.0
PYH2_k127_7384678_20 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000003082 221.0
PYH2_k127_7384678_21 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000004977 211.0
PYH2_k127_7384678_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000002185 204.0
PYH2_k127_7384678_23 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000009069 199.0
PYH2_k127_7384678_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000000001263 191.0
PYH2_k127_7384678_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000003432 191.0
PYH2_k127_7384678_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000002543 176.0
PYH2_k127_7384678_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000005731 154.0
PYH2_k127_7384678_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000003749 152.0
PYH2_k127_7384678_29 Pseudaminic acid biosynthesis N-acetyl transferase K15896 - 2.3.1.202 0.000000000000000000000000000000000000002986 151.0
PYH2_k127_7384678_3 ATPase (AAA K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 558.0
PYH2_k127_7384678_30 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000135 143.0
PYH2_k127_7384678_31 - - - - 0.000000000000000000000000000000000008605 137.0
PYH2_k127_7384678_32 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000002127 126.0
PYH2_k127_7384678_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 532.0
PYH2_k127_7384678_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 447.0
PYH2_k127_7384678_6 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 451.0
PYH2_k127_7384678_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 434.0
PYH2_k127_7384678_8 CMP-N-acetylneuraminic acid synthetase K00983,K15899 - 2.7.7.43,2.7.7.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 414.0
PYH2_k127_7384678_9 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 366.0
PYH2_k127_7494315_0 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 7.37e-248 778.0
PYH2_k127_7494315_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 507.0
PYH2_k127_7494315_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 431.0
PYH2_k127_7494315_3 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 321.0
PYH2_k127_7494315_4 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
PYH2_k127_7494315_5 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004796 258.0
PYH2_k127_7494315_6 - - - - 0.000000000000000000000000000000000000000000000000000002049 192.0
PYH2_k127_7534271_0 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 4.786e-210 656.0
PYH2_k127_7534271_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 404.0
PYH2_k127_7534271_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 254.0
PYH2_k127_7534271_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000001704 137.0
PYH2_k127_7542983_0 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 529.0
PYH2_k127_7542983_1 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 302.0
PYH2_k127_7542983_2 Chemotaxis protein CheW K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001324 267.0
PYH2_k127_7542983_3 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000001368 214.0
PYH2_k127_7542983_4 outer membrane porin, OprD family - - - 0.0000000000004334 80.0
PYH2_k127_7543360_0 permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 464.0
PYH2_k127_7543360_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 295.0
PYH2_k127_7543360_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000001298 192.0
PYH2_k127_7546633_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 9.583e-272 842.0
PYH2_k127_7546633_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.942e-238 738.0
PYH2_k127_7546633_10 (HIT) family - - - 0.00000000000000000000000000000000000000000000000000000000005445 206.0
PYH2_k127_7546633_11 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000001189 198.0
PYH2_k127_7546633_12 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.0000000000000000000000000000000000000000000000000004413 185.0
PYH2_k127_7546633_13 metal-binding, possibly nucleic acid-binding protein - - - 0.000000000000000000000000000000000000000000003255 166.0
PYH2_k127_7546633_14 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000001976 99.0
PYH2_k127_7546633_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 590.0
PYH2_k127_7546633_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 587.0
PYH2_k127_7546633_4 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 580.0
PYH2_k127_7546633_5 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001607 266.0
PYH2_k127_7546633_6 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002663 266.0
PYH2_k127_7546633_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001812 252.0
PYH2_k127_7546633_8 phosphoribosyltransferase K00769 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
PYH2_k127_7546633_9 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000004229 214.0
PYH2_k127_758568_0 Belongs to the CarB family K01955 - 6.3.5.5 4.188e-257 794.0
PYH2_k127_758568_1 rod shape-determining protein mreB K03569 - - 2.043e-209 652.0
PYH2_k127_758568_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002622 242.0
PYH2_k127_758568_3 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000002601 168.0
PYH2_k127_7593190_0 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 2.428e-297 919.0
PYH2_k127_7593190_1 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 572.0
PYH2_k127_7593190_2 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 556.0
PYH2_k127_7593190_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 500.0
PYH2_k127_7593190_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 494.0
PYH2_k127_7593190_5 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 494.0
PYH2_k127_7593190_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008763 252.0
PYH2_k127_7626137_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.167e-290 891.0
PYH2_k127_7626137_1 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 339.0
PYH2_k127_7626137_2 EamA-like transporter family - - - 0.0000000000000000000000000113 111.0
PYH2_k127_7636027_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 4.548e-211 665.0
PYH2_k127_7636027_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 490.0
PYH2_k127_7636027_2 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 396.0
PYH2_k127_7636027_3 DnaJ domain protein K05801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 358.0
PYH2_k127_7636027_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008661 274.0
PYH2_k127_7636027_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008135 256.0
PYH2_k127_7636027_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
PYH2_k127_7636027_7 Histidine kinase - - - 0.000000000000000000000000000006149 124.0
PYH2_k127_7636027_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000004587 111.0
PYH2_k127_7636027_9 lytic transglycosylase activity - - - 0.000000000003024 66.0
PYH2_k127_7640452_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 2.17e-279 862.0
PYH2_k127_7640452_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.69e-278 858.0
PYH2_k127_7640452_2 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 321.0
PYH2_k127_7688745_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 475.0
PYH2_k127_7688745_1 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
PYH2_k127_7695199_0 GAF domain K01768 - 4.6.1.1 0.0 1967.0
PYH2_k127_7695199_1 HD domain - - - 1.383e-253 789.0
PYH2_k127_7695199_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 381.0
PYH2_k127_7695199_11 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 304.0
PYH2_k127_7695199_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001018 253.0
PYH2_k127_7695199_13 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004753 240.0
PYH2_k127_7695199_14 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
PYH2_k127_7695199_15 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000003129 195.0
PYH2_k127_7695199_17 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000000001989 102.0
PYH2_k127_7695199_18 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000002752 69.0
PYH2_k127_7695199_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 4.887e-242 751.0
PYH2_k127_7695199_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 6.804e-224 697.0
PYH2_k127_7695199_4 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 5.574e-195 614.0
PYH2_k127_7695199_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 574.0
PYH2_k127_7695199_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 512.0
PYH2_k127_7695199_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 488.0
PYH2_k127_7695199_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 434.0
PYH2_k127_7695199_9 molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 428.0
PYH2_k127_7762881_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1156.0
PYH2_k127_7762881_1 Sigma factor PP2C-like phosphatases - - - 1.827e-296 915.0
PYH2_k127_7762881_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 446.0
PYH2_k127_7762881_11 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 442.0
PYH2_k127_7762881_12 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 391.0
PYH2_k127_7762881_13 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 387.0
PYH2_k127_7762881_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 317.0
PYH2_k127_7762881_15 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 301.0
PYH2_k127_7762881_16 chemotaxis protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 282.0
PYH2_k127_7762881_17 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 285.0
PYH2_k127_7762881_18 protein conserved in bacteria K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
PYH2_k127_7762881_19 Domain of unknown function (DUF1987) - - - 0.00000000000000000000000000000000000000000000000000000000000007874 214.0
PYH2_k127_7762881_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.021e-278 862.0
PYH2_k127_7762881_20 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002738 212.0
PYH2_k127_7762881_22 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000001346 196.0
PYH2_k127_7762881_23 Cupin - - - 0.00000000000000000000000000000000000000000000000000004414 191.0
PYH2_k127_7762881_24 SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000002905 184.0
PYH2_k127_7762881_25 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000003192 95.0
PYH2_k127_7762881_26 Fe2 transport system protein A K04758 - - 0.000000000000009717 77.0
PYH2_k127_7762881_3 chemotaxis protein K03407 - 2.7.13.3 1.019e-270 857.0
PYH2_k127_7762881_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.748e-268 827.0
PYH2_k127_7762881_5 PFAM EAL domain - - - 2.695e-259 813.0
PYH2_k127_7762881_6 DNA recombination protein K09760 - - 2.319e-222 696.0
PYH2_k127_7762881_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 595.0
PYH2_k127_7762881_8 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 543.0
PYH2_k127_7762881_9 chemotaxis protein K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 517.0
PYH2_k127_7786890_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1080.0
PYH2_k127_7786890_1 The M ring may be actively involved in energy transduction K02409 - - 4.403e-272 846.0
PYH2_k127_7786890_2 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 4.874e-210 658.0
PYH2_k127_7786890_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 2.155e-206 645.0
PYH2_k127_7786890_4 flagellar motor switch protein K02410 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 557.0
PYH2_k127_7786890_5 flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
PYH2_k127_7786890_6 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002613 259.0
PYH2_k127_7786890_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000004434 155.0
PYH2_k127_7861647_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0 1616.0
PYH2_k127_7861647_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 9.874e-304 935.0
PYH2_k127_7861647_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 474.0
PYH2_k127_7861647_11 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 397.0
PYH2_k127_7861647_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 381.0
PYH2_k127_7861647_13 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 385.0
PYH2_k127_7861647_14 Domain of unknown function (DUF1882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 334.0
PYH2_k127_7861647_15 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
PYH2_k127_7861647_16 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 290.0
PYH2_k127_7861647_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005773 225.0
PYH2_k127_7861647_18 17 kDa surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
PYH2_k127_7861647_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000006272 199.0
PYH2_k127_7861647_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.506e-277 855.0
PYH2_k127_7861647_20 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000006405 154.0
PYH2_k127_7861647_21 Histidine kinase - - - 0.0000000000000000000000000000000000003804 146.0
PYH2_k127_7861647_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000001024 140.0
PYH2_k127_7861647_23 Sporulation related domain K03591,K03749 - - 0.0000000000000000000000000000001653 124.0
PYH2_k127_7861647_24 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.0000000000000003303 78.0
PYH2_k127_7861647_3 Belongs to the FtsK SpoIIIE SftA family K03466 - - 1.623e-273 860.0
PYH2_k127_7861647_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 2.208e-255 789.0
PYH2_k127_7861647_5 twitching motility protein K02669 - - 6.887e-205 641.0
PYH2_k127_7861647_6 chemotaxis protein - - - 1.765e-199 631.0
PYH2_k127_7861647_7 Belongs to the GPI family K01810 - 5.3.1.9 5.587e-196 618.0
PYH2_k127_7861647_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 595.0
PYH2_k127_7861647_9 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 591.0
PYH2_k127_7861787_0 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 9.104e-202 631.0
PYH2_k127_7861787_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 554.0
PYH2_k127_7861787_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 385.0
PYH2_k127_7861787_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 332.0
PYH2_k127_7861787_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000000003641 179.0
PYH2_k127_7868053_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 4.236e-248 767.0
PYH2_k127_7868053_1 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 563.0
PYH2_k127_7868053_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000000112 196.0
PYH2_k127_7868053_3 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000001071 175.0
PYH2_k127_7871775_0 Aminotransferase K14261 - - 4.365e-258 796.0
PYH2_k127_7871775_1 homoserine dehydrogenase K00003 - 1.1.1.3 3.26e-220 689.0
PYH2_k127_7871775_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000407 246.0
PYH2_k127_7871775_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000002776 215.0
PYH2_k127_7871775_12 ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002383 209.0
PYH2_k127_7871775_14 Nitrogen fixation protein NifU - - - 0.000000000000000000000000000000000000003723 147.0
PYH2_k127_7871775_16 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000003794 129.0
PYH2_k127_7871775_17 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000005039 77.0
PYH2_k127_7871775_2 molybdopterin biosynthesis K03750 - 2.10.1.1 1.335e-206 648.0
PYH2_k127_7871775_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 605.0
PYH2_k127_7871775_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 451.0
PYH2_k127_7871775_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 402.0
PYH2_k127_7871775_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 391.0
PYH2_k127_7871775_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 314.0
PYH2_k127_7871775_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001983 250.0
PYH2_k127_7871775_9 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000002935 239.0
PYH2_k127_7874621_0 diguanylate cyclase - - - 0.0 1036.0
PYH2_k127_7874621_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.653e-289 889.0
PYH2_k127_7874621_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002403 273.0
PYH2_k127_7874621_11 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000002332 247.0
PYH2_k127_7874621_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.000000000000000000000000000000000000000000000000000000000088 206.0
PYH2_k127_7874621_13 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000002286 175.0
PYH2_k127_7874621_14 response regulator - - - 0.00001194 56.0
PYH2_k127_7874621_2 GGDEF domain - - - 5.083e-260 813.0
PYH2_k127_7874621_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 2.902e-231 718.0
PYH2_k127_7874621_4 sulfate adenylyltransferase K00958 - 2.7.7.4 9.874e-219 683.0
PYH2_k127_7874621_5 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 579.0
PYH2_k127_7874621_6 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 571.0
PYH2_k127_7874621_7 4fe-4s ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 555.0
PYH2_k127_7874621_8 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 390.0
PYH2_k127_7874621_9 component of anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 350.0
PYH2_k127_7920713_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1142.0
PYH2_k127_7920713_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03212,K03215 - 2.1.1.189,2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 537.0
PYH2_k127_7920713_2 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 497.0
PYH2_k127_7920713_3 metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 470.0
PYH2_k127_7920713_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 261.0
PYH2_k127_7920713_5 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000006046 226.0
PYH2_k127_7920713_6 endonuclease III K07457 - - 0.00000000000000000000000000000000000002581 146.0
PYH2_k127_7934009_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 336.0
PYH2_k127_7934009_1 Sensory box GGDEF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 299.0
PYH2_k127_7934009_2 - - - - 0.00000000000000000000000001993 109.0
PYH2_k127_7958966_0 COG0642 Signal transduction histidine kinase - - - 2.411e-312 967.0
PYH2_k127_7958966_1 Histidine kinase K20972 - - 2.979e-290 902.0
PYH2_k127_7958966_10 flagellar motor K02557 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 366.0
PYH2_k127_7958966_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 347.0
PYH2_k127_7958966_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 310.0
PYH2_k127_7958966_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 306.0
PYH2_k127_7958966_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 318.0
PYH2_k127_7958966_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000005115 235.0
PYH2_k127_7958966_16 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000001104 223.0
PYH2_k127_7958966_17 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000009798 163.0
PYH2_k127_7958966_18 DNA-binding protein - - - 0.000000000000000000000000000000000001352 139.0
PYH2_k127_7958966_19 - - - - 0.0000000000000000000005141 97.0
PYH2_k127_7958966_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.848e-239 747.0
PYH2_k127_7958966_3 Na H antiporter - - - 2.623e-212 663.0
PYH2_k127_7958966_4 fructose-bisphosphate aldolase K01624 - 4.1.2.13 2.931e-207 647.0
PYH2_k127_7958966_5 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 438.0
PYH2_k127_7958966_6 forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 430.0
PYH2_k127_7958966_7 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 425.0
PYH2_k127_7958966_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 369.0
PYH2_k127_7958966_9 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 371.0
PYH2_k127_8138659_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1107.0
PYH2_k127_8138659_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.342e-262 809.0
PYH2_k127_8138659_2 TonB dependent receptor - - - 1.179e-246 779.0
PYH2_k127_8138659_3 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 492.0
PYH2_k127_8138659_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 417.0
PYH2_k127_8138659_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 336.0
PYH2_k127_8138659_6 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 304.0
PYH2_k127_8138659_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000004636 170.0
PYH2_k127_816831_0 flagellar biosynthesis K02404 - - 3.986e-242 752.0
PYH2_k127_816831_1 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 434.0
PYH2_k127_816831_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 301.0
PYH2_k127_816831_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000005352 229.0
PYH2_k127_8282401_0 Heterodisulfide reductase subunit B K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 576.0
PYH2_k127_8282401_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 578.0
PYH2_k127_8282401_10 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000005913 201.0
PYH2_k127_8282401_11 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000002256 159.0
PYH2_k127_8282401_12 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000008264 116.0
PYH2_k127_8282401_13 CHAD - - - 0.0000005852 60.0
PYH2_k127_8282401_2 chemotaxis protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 564.0
PYH2_k127_8282401_3 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 487.0
PYH2_k127_8282401_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 436.0
PYH2_k127_8282401_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 422.0
PYH2_k127_8282401_6 GGDEF domain - GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 424.0
PYH2_k127_8282401_7 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 312.0
PYH2_k127_8282401_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
PYH2_k127_8282401_9 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002075 277.0
PYH2_k127_8396343_0 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 355.0
PYH2_k127_8396343_1 riboflavin synthase alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 352.0
PYH2_k127_8396343_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 346.0
PYH2_k127_8396343_3 Pfam Transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
PYH2_k127_8396343_4 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 313.0
PYH2_k127_8396343_5 Histidine kinase K03406,K05875,K07647 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004275 272.0
PYH2_k127_8425157_0 mechanosensitive ion channel - - - 1.201e-246 771.0
PYH2_k127_8425157_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.878e-224 700.0
PYH2_k127_8425157_10 S4 domain protein - - - 0.00000000000000000000000000000000004278 135.0
PYH2_k127_8425157_2 domain protein K09944 - - 2.806e-220 691.0
PYH2_k127_8425157_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 591.0
PYH2_k127_8425157_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 539.0
PYH2_k127_8425157_5 MiaB-like tRNA modifying enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 445.0
PYH2_k127_8425157_6 ABC transporter, ATP-binding protein K01990,K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 438.0
PYH2_k127_8425157_7 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 424.0
PYH2_k127_8425157_8 tigr02757 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
PYH2_k127_8425157_9 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000000000000000000000000000000004989 224.0
PYH2_k127_8432967_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 359.0
PYH2_k127_8432967_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 297.0
PYH2_k127_8443929_0 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 421.0
PYH2_k127_8443929_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 368.0
PYH2_k127_8443929_2 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 318.0
PYH2_k127_8443929_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000466 301.0
PYH2_k127_8443929_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006788 273.0
PYH2_k127_8443929_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000009191 157.0
PYH2_k127_8443929_6 amino acid transport K02030,K10001 - - 0.00000000000000000000000000000000000833 147.0
PYH2_k127_8443929_7 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000104 65.0
PYH2_k127_8443929_9 regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.000002199 53.0
PYH2_k127_8474400_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1369.0
PYH2_k127_8474400_1 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1104.0
PYH2_k127_8474400_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 429.0
PYH2_k127_8474400_11 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 389.0
PYH2_k127_8474400_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 389.0
PYH2_k127_8474400_13 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 374.0
PYH2_k127_8474400_14 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 368.0
PYH2_k127_8474400_15 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 332.0
PYH2_k127_8474400_16 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 284.0
PYH2_k127_8474400_17 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002764 246.0
PYH2_k127_8474400_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000137 227.0
PYH2_k127_8474400_19 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000000002327 220.0
PYH2_k127_8474400_2 peptidase M23 - - - 1.533e-245 764.0
PYH2_k127_8474400_20 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000009612 198.0
PYH2_k127_8474400_21 oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000000000000108 187.0
PYH2_k127_8474400_22 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000005509 179.0
PYH2_k127_8474400_23 COG1214 Inactive homolog of metal-dependent proteases - - - 0.000000000000000000000000000000000000000000007607 167.0
PYH2_k127_8474400_24 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000001011 159.0
PYH2_k127_8474400_25 nucleic-acid-binding protein implicated in transcription termination - - - 0.0000000000002662 72.0
PYH2_k127_8474400_3 Receptor - - - 2.235e-211 667.0
PYH2_k127_8474400_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 601.0
PYH2_k127_8474400_5 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 584.0
PYH2_k127_8474400_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 548.0
PYH2_k127_8474400_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 510.0
PYH2_k127_8474400_8 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 505.0
PYH2_k127_8474400_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 442.0
PYH2_k127_8520601_0 AsmA-like C-terminal region - - - 5.747e-282 897.0
PYH2_k127_8520601_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.549e-198 623.0
PYH2_k127_8520601_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006262 274.0
PYH2_k127_8522908_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 6.966e-226 701.0
PYH2_k127_8522908_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 495.0
PYH2_k127_8522908_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 478.0
PYH2_k127_8522908_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 451.0
PYH2_k127_8522908_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 312.0
PYH2_k127_8522908_5 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008895 275.0
PYH2_k127_8522908_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003435 259.0
PYH2_k127_8522908_7 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000001732 196.0
PYH2_k127_8522908_8 - - - - 0.0000000000000000000000000000000000000000000000000004545 185.0
PYH2_k127_8522908_9 Cytochrome c - - - 0.00000000000000000000000001189 113.0
PYH2_k127_8527328_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3.43e-318 998.0
PYH2_k127_8527328_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.156e-264 824.0
PYH2_k127_8527328_2 COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 1.453e-238 749.0
PYH2_k127_8527328_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 563.0
PYH2_k127_8527328_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 334.0
PYH2_k127_8527328_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
PYH2_k127_8527328_6 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000000000000000003508 253.0
PYH2_k127_8527328_7 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001686 210.0
PYH2_k127_8527328_8 alpha-ribazole phosphatase activity K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000152 173.0
PYH2_k127_8532406_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 606.0
PYH2_k127_8532406_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 364.0
PYH2_k127_8532406_2 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 327.0
PYH2_k127_8532406_3 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
PYH2_k127_8532406_4 biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000000000000000000006598 217.0
PYH2_k127_8532406_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000006556 176.0
PYH2_k127_8532406_6 DNA-binding protein - - - 0.00000004052 54.0
PYH2_k127_8597095_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 605.0
PYH2_k127_8597095_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 519.0
PYH2_k127_8597095_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 333.0
PYH2_k127_8597095_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
PYH2_k127_8597095_5 - - - - 0.000000000000000000000000000004205 119.0
PYH2_k127_8597095_6 Prokaryotic metallothionein K06950 - - 0.000000000000000000001377 96.0
PYH2_k127_8603_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1250.0
PYH2_k127_8603_1 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 367.0
PYH2_k127_8603_2 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000000005109 171.0
PYH2_k127_8603_3 PFAM DNA polymerase, beta domain protein region K07075 - - 0.0000000000401 68.0
PYH2_k127_8666775_0 Flagellar Assembly Protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 548.0
PYH2_k127_8666775_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 364.0
PYH2_k127_8666775_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 347.0
PYH2_k127_8666775_4 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000000000000000000000000000005628 128.0
PYH2_k127_8740763_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 484.0
PYH2_k127_8740763_1 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 490.0
PYH2_k127_8740763_2 GatB Yqey family protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000007507 221.0
PYH2_k127_8740763_3 Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000000000000003423 154.0
PYH2_k127_8950284_0 Glutathionylspermidine synthase - - - 2.221e-223 696.0
PYH2_k127_8950284_1 flagellar hook-associated protein K02396 - - 4.713e-206 652.0
PYH2_k127_8950284_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 432.0
PYH2_k127_8950284_3 - - - - 0.000000000000000000000000000000000000006579 147.0
PYH2_k127_9021414_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.405e-243 751.0
PYH2_k127_9021414_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 394.0
PYH2_k127_9021414_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 372.0
PYH2_k127_9021414_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003355 261.0
PYH2_k127_9021414_4 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
PYH2_k127_9021414_5 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.00000002786 55.0
PYH2_k127_9100700_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 561.0
PYH2_k127_9100700_1 HIT family - - - 0.000000000000000000000000000000000000002655 147.0
PYH2_k127_9100700_2 Belongs to the ompA family K03286 - - 0.0000000000000000000001206 98.0
PYH2_k127_9100700_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000009623 99.0
PYH2_k127_9100700_4 Tetratricopeptide repeat - - - 0.000001487 57.0
PYH2_k127_9100700_5 COG1413 FOG HEAT repeat - - - 0.0002839 53.0
PYH2_k127_9215889_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 529.0
PYH2_k127_9215889_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 437.0
PYH2_k127_9215889_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 428.0
PYH2_k127_9215889_3 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000001102 194.0
PYH2_k127_9215889_4 - - - - 0.000000000000000000000000000000000000001129 156.0
PYH2_k127_9225139_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1011.0
PYH2_k127_9225139_1 Diguanylate cyclase with PAS PAC sensor - - - 1.855e-209 662.0
PYH2_k127_9225139_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002038 281.0
PYH2_k127_9225139_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000001722 229.0
PYH2_k127_9225139_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000006466 155.0
PYH2_k127_9225139_5 Diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000008589 132.0
PYH2_k127_956875_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.008e-293 904.0
PYH2_k127_956875_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 4.828e-207 646.0
PYH2_k127_956875_10 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000002315 209.0
PYH2_k127_956875_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000000000002968 191.0
PYH2_k127_956875_12 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000005636 187.0
PYH2_k127_956875_13 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000001094 165.0
PYH2_k127_956875_14 peptidyl-prolyl K03775 - 5.2.1.8 0.000000000000000000000000000003395 121.0
PYH2_k127_956875_15 Protein of unknown function, DUF255 - - - 0.00000000000006467 77.0
PYH2_k127_956875_2 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 489.0
PYH2_k127_956875_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 448.0
PYH2_k127_956875_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 441.0
PYH2_k127_956875_5 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 428.0
PYH2_k127_956875_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 304.0
PYH2_k127_956875_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005802 252.0
PYH2_k127_956875_8 Belongs to the ATPase B chain family K02109 - - 0.000000000000000000000000000000000000000000000000000000000000006281 219.0
PYH2_k127_956875_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000001344 213.0