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Overview

ID MAG03188
Name PYH2_bin.38
Sample SMP0074
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order 40CM-2-53-6
Family 40CM-2-53-6
Genus
Species
Assembly information
Completeness (%) 86.91
Contamination (%) 5.97
GC content (%) 53.0
N50 (bp) 13,350
Genome size (bp) 2,042,452

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1916

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1025109_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000001742 245.0
PYH2_k127_1025109_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000003191 234.0
PYH2_k127_1025109_2 zinc finger - - - 0.0000000000000000000000000000000000000000000000002298 186.0
PYH2_k127_1025109_3 NhaP-type Na H and K H K03316 - - 0.0000000000000000000000000000000000000000000008171 181.0
PYH2_k127_1025109_4 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000001424 59.0
PYH2_k127_103480_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 362.0
PYH2_k127_103480_1 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 301.0
PYH2_k127_103480_10 - - - - 0.0000003604 57.0
PYH2_k127_103480_11 Putative adhesin - - - 0.00001739 54.0
PYH2_k127_103480_12 Protein of unknown function (DUF3796) - - - 0.000019 51.0
PYH2_k127_103480_13 GH3 auxin-responsive promoter - - - 0.00006392 55.0
PYH2_k127_103480_2 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009603 274.0
PYH2_k127_103480_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
PYH2_k127_103480_4 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000002715 207.0
PYH2_k127_103480_5 - - - - 0.000000000000000000000000000000000000000000000000000002268 204.0
PYH2_k127_103480_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000001269 85.0
PYH2_k127_103480_7 Rubrerythrin - - - 0.000000000000009449 80.0
PYH2_k127_103480_8 Transcriptional regulator K07729 - - 0.00000000000003759 74.0
PYH2_k127_103480_9 Bacterial transcription activator, effector binding domain - - - 0.000000006353 64.0
PYH2_k127_1063658_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 578.0
PYH2_k127_1063658_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 530.0
PYH2_k127_1063658_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
PYH2_k127_1063658_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000368 243.0
PYH2_k127_1063658_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
PYH2_k127_1063658_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000001967 206.0
PYH2_k127_1063658_14 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000005604 199.0
PYH2_k127_1063658_15 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000005135 188.0
PYH2_k127_1063658_16 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000001805 187.0
PYH2_k127_1063658_17 membrane K08979 - - 0.000000000000000000000000000000000000000000003623 185.0
PYH2_k127_1063658_18 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000003731 173.0
PYH2_k127_1063658_19 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000001875 154.0
PYH2_k127_1063658_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 467.0
PYH2_k127_1063658_20 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000003295 143.0
PYH2_k127_1063658_21 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.00000000000000000002575 94.0
PYH2_k127_1063658_22 Ferric reductase like transmembrane component - - - 0.000000000000000007908 96.0
PYH2_k127_1063658_23 AraC-like ligand binding domain - - - 0.000000000000005314 79.0
PYH2_k127_1063658_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000004342 71.0
PYH2_k127_1063658_25 Thiamine pyrophosphate enzyme, central domain K01652,K16787 - 2.2.1.6 0.00000000001044 67.0
PYH2_k127_1063658_26 CBS domain - - - 0.000000001361 70.0
PYH2_k127_1063658_27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000001715 53.0
PYH2_k127_1063658_28 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.0000003196 57.0
PYH2_k127_1063658_29 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000004155 54.0
PYH2_k127_1063658_3 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 383.0
PYH2_k127_1063658_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 362.0
PYH2_k127_1063658_5 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
PYH2_k127_1063658_6 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 324.0
PYH2_k127_1063658_7 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
PYH2_k127_1063658_8 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 295.0
PYH2_k127_1063658_9 GHMP kinases C terminal K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
PYH2_k127_1085139_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 477.0
PYH2_k127_1170823_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000001014 202.0
PYH2_k127_1170823_1 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000001886 152.0
PYH2_k127_1217030_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 374.0
PYH2_k127_1217030_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 359.0
PYH2_k127_1217030_10 PEP-utilising enzyme, mobile domain - - - 0.0000000000000001258 84.0
PYH2_k127_1217030_11 PFAM Radical SAM domain protein - - - 0.00000000000005657 79.0
PYH2_k127_1217030_12 Protein of unknown function DUF47 K07220 - - 0.00000000007459 71.0
PYH2_k127_1217030_13 PFAM 4Fe-4S ferredoxin - - - 0.000000001351 61.0
PYH2_k127_1217030_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000001712 53.0
PYH2_k127_1217030_2 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
PYH2_k127_1217030_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
PYH2_k127_1217030_4 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361 282.0
PYH2_k127_1217030_5 ATPases associated with a variety of cellular activities K10112,K17240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003278 268.0
PYH2_k127_1217030_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000000000000000000000000000002002 239.0
PYH2_k127_1217030_7 - - - - 0.0000000000000000000000000000005878 134.0
PYH2_k127_1217030_8 PEP-utilising enzyme, mobile domain - - - 0.00000000000000000001524 104.0
PYH2_k127_1217030_9 GIY-YIG catalytic domain K07461 - - 0.00000000000000006382 83.0
PYH2_k127_1223890_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001048 246.0
PYH2_k127_1223890_1 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000002637 241.0
PYH2_k127_1223890_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
PYH2_k127_1223890_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000001024 204.0
PYH2_k127_1223890_4 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000007452 186.0
PYH2_k127_1223890_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000007007 158.0
PYH2_k127_1223890_6 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000703 124.0
PYH2_k127_123067_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 306.0
PYH2_k127_123067_1 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000001566 177.0
PYH2_k127_123067_2 - - - - 0.00000008592 59.0
PYH2_k127_1243199_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 522.0
PYH2_k127_1243199_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 355.0
PYH2_k127_1243199_2 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 342.0
PYH2_k127_1243199_3 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000001407 106.0
PYH2_k127_1243199_4 Transcriptional regulator K11924 - - 0.000000000000005276 80.0
PYH2_k127_1243199_5 Lrp/AsnC ligand binding domain - - - 0.00000294 52.0
PYH2_k127_1243199_6 Lrp/AsnC ligand binding domain - - - 0.00002144 51.0
PYH2_k127_1243199_7 - - - - 0.0002017 51.0
PYH2_k127_1243199_8 Protein of unknown function (DUF2721) - - - 0.0003206 49.0
PYH2_k127_1278003_0 Sulfate permease K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 472.0
PYH2_k127_1278003_1 Transposase - - - 0.0000000000003178 79.0
PYH2_k127_1278003_2 Major facilitator superfamily - - - 0.000001986 60.0
PYH2_k127_1278003_3 Phage integrase family - - - 0.0002392 47.0
PYH2_k127_129189_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 391.0
PYH2_k127_129189_1 VIT family - - - 0.000000000000000000000000000000000000003137 159.0
PYH2_k127_129189_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.000000000392 69.0
PYH2_k127_129189_3 - - - - 0.00000004266 58.0
PYH2_k127_1293226_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000001219 228.0
PYH2_k127_1293226_1 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000739 218.0
PYH2_k127_1293226_2 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000001925 202.0
PYH2_k127_1293226_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000001003 181.0
PYH2_k127_1293226_4 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000004966 129.0
PYH2_k127_1349019_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 614.0
PYH2_k127_1349019_1 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 400.0
PYH2_k127_1349019_2 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
PYH2_k127_1349019_3 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007485 280.0
PYH2_k127_1349019_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000008507 274.0
PYH2_k127_1349019_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000005745 126.0
PYH2_k127_1349019_6 - K02339 - 2.7.7.7 0.00000000000003361 81.0
PYH2_k127_1397968_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000002286 221.0
PYH2_k127_1449701_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 596.0
PYH2_k127_1449701_1 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 558.0
PYH2_k127_1449701_10 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
PYH2_k127_1449701_11 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000116 233.0
PYH2_k127_1449701_12 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000003128 228.0
PYH2_k127_1449701_13 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000000000001091 202.0
PYH2_k127_1449701_14 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000298 175.0
PYH2_k127_1449701_15 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000002365 186.0
PYH2_k127_1449701_16 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000000001569 176.0
PYH2_k127_1449701_17 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000001815 150.0
PYH2_k127_1449701_18 VIT family - - - 0.00000000000000000000000000000002543 136.0
PYH2_k127_1449701_19 PGAP1-like protein - - - 0.00000000000000000000000000000004846 127.0
PYH2_k127_1449701_2 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 445.0
PYH2_k127_1449701_20 4Fe-4S binding domain - - - 0.000000000000000000000000001426 124.0
PYH2_k127_1449701_21 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.00000000000000000000001008 102.0
PYH2_k127_1449701_22 UPF0056 membrane protein K05595 - - 0.000000000000000000001474 103.0
PYH2_k127_1449701_23 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000001623 102.0
PYH2_k127_1449701_24 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.00000000000000000007464 92.0
PYH2_k127_1449701_25 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.0000000000000001417 84.0
PYH2_k127_1449701_26 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.0000000000007908 73.0
PYH2_k127_1449701_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000005662 74.0
PYH2_k127_1449701_28 - - - - 0.00000000002457 74.0
PYH2_k127_1449701_29 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00007329 54.0
PYH2_k127_1449701_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 443.0
PYH2_k127_1449701_4 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 412.0
PYH2_k127_1449701_5 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 393.0
PYH2_k127_1449701_6 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 346.0
PYH2_k127_1449701_7 UbiA prenyltransferase family K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 296.0
PYH2_k127_1449701_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000706 278.0
PYH2_k127_1449701_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001725 276.0
PYH2_k127_1480727_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 2.704e-299 955.0
PYH2_k127_1480727_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 551.0
PYH2_k127_1480727_10 PFAM Transcription elongation factor Elf1 like - - - 0.000000000003115 70.0
PYH2_k127_1480727_12 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0004335 47.0
PYH2_k127_1480727_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 469.0
PYH2_k127_1480727_3 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
PYH2_k127_1480727_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 301.0
PYH2_k127_1480727_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000001301 213.0
PYH2_k127_1480727_6 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000002358 178.0
PYH2_k127_1480727_7 COG0778 Nitroreductase K10678,K19285 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016657,GO:0032553,GO:0034567,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.38 0.000000000000000000000000000000008194 137.0
PYH2_k127_1480727_8 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000006189 124.0
PYH2_k127_1480727_9 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000008442 98.0
PYH2_k127_149158_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.44e-206 663.0
PYH2_k127_149158_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 440.0
PYH2_k127_149158_10 - - - - 0.0001645 51.0
PYH2_k127_149158_11 C-terminal domain of CHU protein family - - - 0.0009632 52.0
PYH2_k127_149158_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
PYH2_k127_149158_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 348.0
PYH2_k127_149158_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
PYH2_k127_149158_5 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004793 268.0
PYH2_k127_149158_6 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000002323 184.0
PYH2_k127_149158_7 - - - - 0.00000000000000000000000000000000008799 140.0
PYH2_k127_149158_8 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000009049 111.0
PYH2_k127_1512204_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 490.0
PYH2_k127_1512204_1 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000002232 211.0
PYH2_k127_1512204_2 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.00000000000000000000000000000000000001414 149.0
PYH2_k127_1512204_3 - - - - 0.0000002657 57.0
PYH2_k127_1512204_5 MarR family - - - 0.00001921 53.0
PYH2_k127_1549097_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 369.0
PYH2_k127_1549097_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 366.0
PYH2_k127_1549097_10 helix_turn_helix ASNC type K03719 - - 0.0000000000000000002769 93.0
PYH2_k127_1549097_11 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide K01574 - 4.1.1.4 0.00000000002344 73.0
PYH2_k127_1549097_2 PFAM Metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 314.0
PYH2_k127_1549097_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 297.0
PYH2_k127_1549097_4 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001434 291.0
PYH2_k127_1549097_5 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
PYH2_k127_1549097_6 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000003993 222.0
PYH2_k127_1549097_7 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000001649 213.0
PYH2_k127_1549097_8 - - - - 0.000000000000000000000000000000000000000000001483 174.0
PYH2_k127_1549097_9 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.00000000000000000000000000000001535 142.0
PYH2_k127_1561272_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.523e-196 622.0
PYH2_k127_1561272_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 537.0
PYH2_k127_1561272_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000007801 238.0
PYH2_k127_1561272_3 ATPases associated with a variety of cellular activities K02017,K15497 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000007177 235.0
PYH2_k127_1561272_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000006011 218.0
PYH2_k127_1561272_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000006078 213.0
PYH2_k127_1562091_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1036.0
PYH2_k127_1562091_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 8.91e-248 796.0
PYH2_k127_1562091_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0002224 46.0
PYH2_k127_1562091_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 305.0
PYH2_k127_1562091_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000001847 217.0
PYH2_k127_1562091_4 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001019 208.0
PYH2_k127_1562091_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000001387 179.0
PYH2_k127_1562091_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000003743 107.0
PYH2_k127_1562091_7 Transcription elongation factor Spt5 K02601 - - 0.0000000000004962 72.0
PYH2_k127_1562091_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000009053 74.0
PYH2_k127_1562091_9 PFAM Ribosomal L18ae LX protein domain K02944 - - 0.00000006724 56.0
PYH2_k127_159348_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 532.0
PYH2_k127_159348_1 converts alpha-aldose to the beta-anomer - - - 0.000002774 52.0
PYH2_k127_166488_0 COGs COG1024 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
PYH2_k127_166488_1 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000009995 187.0
PYH2_k127_166488_10 - - - - 0.00002959 55.0
PYH2_k127_166488_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000001063 173.0
PYH2_k127_166488_3 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000000000000001611 166.0
PYH2_k127_166488_4 Psort location Cytoplasmic, score K09707 - - 0.00000000000000000000000000000000000005338 145.0
PYH2_k127_166488_5 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.0000000000000000000000006509 108.0
PYH2_k127_166488_6 - - - - 0.0000000008792 68.0
PYH2_k127_166488_7 Integron-associated effector binding protein - - - 0.000000006475 63.0
PYH2_k127_166488_8 Belongs to the ParB family K03497 - - 0.000000188 61.0
PYH2_k127_166488_9 Cupin - - - 0.000001146 57.0
PYH2_k127_166841_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 514.0
PYH2_k127_166841_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 477.0
PYH2_k127_166841_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 370.0
PYH2_k127_166841_3 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000001302 201.0
PYH2_k127_166841_4 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.0000000000000000000000000000000000000000000000002195 185.0
PYH2_k127_166841_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.0000000000000000000000000000004811 127.0
PYH2_k127_166841_6 PFAM Mov34 MPN PAD-1 family - - - 0.000000000000002292 82.0
PYH2_k127_166841_7 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00001479 50.0
PYH2_k127_166841_8 - - - - 0.0000417 51.0
PYH2_k127_17088_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 483.0
PYH2_k127_17088_1 PFAM hydrogenase formation HypD protein K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 451.0
PYH2_k127_17088_2 Predicted Permease Membrane Region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 398.0
PYH2_k127_17088_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 347.0
PYH2_k127_17088_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 306.0
PYH2_k127_17088_5 PFAM SpoVT AbrB - - - 0.000000000000000000000000000000000000000000004298 177.0
PYH2_k127_17088_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000001277 100.0
PYH2_k127_17088_7 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.0000000000000000000003996 103.0
PYH2_k127_1828257_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.285e-204 652.0
PYH2_k127_1828257_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 543.0
PYH2_k127_1828257_10 Thiamine biosynthesis protein (ThiI) K06920 - 6.3.4.20 0.00000000000000000000000000000000002389 143.0
PYH2_k127_1828257_11 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000007207 108.0
PYH2_k127_1828257_12 - - - - 0.00000000000000000007389 97.0
PYH2_k127_1828257_13 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000001434 78.0
PYH2_k127_1828257_14 Phosphate transport regulator K07220 - - 0.000000000003326 77.0
PYH2_k127_1828257_15 DNA polymerase beta domain protein region - - - 0.000000561 59.0
PYH2_k127_1828257_2 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 445.0
PYH2_k127_1828257_3 DUF72 domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003854 241.0
PYH2_k127_1828257_4 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005646 227.0
PYH2_k127_1828257_5 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000006654 166.0
PYH2_k127_1828257_6 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000004118 162.0
PYH2_k127_1828257_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000013 151.0
PYH2_k127_1828257_8 nUDIX hydrolase K01515,K01518,K01814 - 3.6.1.13,3.6.1.17,5.3.1.16 0.000000000000000000000000000000000004008 143.0
PYH2_k127_1828257_9 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000001768 147.0
PYH2_k127_185202_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 4.888e-217 677.0
PYH2_k127_185202_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 3.923e-211 684.0
PYH2_k127_185202_2 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 446.0
PYH2_k127_185202_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
PYH2_k127_185202_4 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 364.0
PYH2_k127_185202_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000002724 195.0
PYH2_k127_185202_6 Dimerisation domain of Zinc Transporter - - - 0.00007871 53.0
PYH2_k127_1879329_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 434.0
PYH2_k127_1879329_1 transferase hexapeptide repeat - - - 0.00000000000000000000000000000000000000000007189 169.0
PYH2_k127_1879329_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000004594 71.0
PYH2_k127_1884418_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1043.0
PYH2_k127_1884418_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 464.0
PYH2_k127_1884418_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000005268 187.0
PYH2_k127_1884418_11 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000003405 173.0
PYH2_k127_1884418_12 Major Facilitator K08177 - - 0.000000000000000000000002771 109.0
PYH2_k127_1884418_13 TOBE domain - - - 0.000000000000000000002311 94.0
PYH2_k127_1884418_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000427 104.0
PYH2_k127_1884418_16 - - - - 0.000000000000001624 80.0
PYH2_k127_1884418_17 - - - - 0.000003124 58.0
PYH2_k127_1884418_2 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 379.0
PYH2_k127_1884418_3 l-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 385.0
PYH2_k127_1884418_4 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 327.0
PYH2_k127_1884418_5 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 265.0
PYH2_k127_1884418_6 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000007491 219.0
PYH2_k127_1884418_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000001693 216.0
PYH2_k127_1884418_8 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
PYH2_k127_1884418_9 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000009666 206.0
PYH2_k127_1884725_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 296.0
PYH2_k127_1884725_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000001637 219.0
PYH2_k127_1884725_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000001083 162.0
PYH2_k127_1884725_3 Belongs to the phosphohexose mutase family K22199 - 5.4.2.7 0.000000000000000000000000000000008121 133.0
PYH2_k127_1903678_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002219 282.0
PYH2_k127_1903678_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000007441 226.0
PYH2_k127_1903678_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000344 171.0
PYH2_k127_1909157_0 PFAM aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 567.0
PYH2_k127_1909157_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
PYH2_k127_1922208_0 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001336 230.0
PYH2_k127_1922208_1 ferredoxin-NADP+ reductase activity K00384 - 1.8.1.9 0.000000000000000000000000000001084 133.0
PYH2_k127_1940633_0 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007626 273.0
PYH2_k127_1940633_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH2_k127_1940633_2 - - - - 0.00000000000000000000000000000000000000000000001314 180.0
PYH2_k127_1940633_3 amino acid - - - 0.00000000000000000000000000000000002162 151.0
PYH2_k127_1940633_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000001042 119.0
PYH2_k127_1948914_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 475.0
PYH2_k127_1948914_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000001328 64.0
PYH2_k127_1980679_0 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 340.0
PYH2_k127_1980679_2 metal-dependent membrane protease K07052 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000001742 202.0
PYH2_k127_1980679_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000000003168 214.0
PYH2_k127_1980679_4 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000003659 126.0
PYH2_k127_1980679_5 Protein of unknown function (DUF998) - - - 0.0000000000000000000001277 100.0
PYH2_k127_1980679_6 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000004259 89.0
PYH2_k127_1980679_7 PFAM Metallophosphoesterase K03547 - - 0.000000000000001679 89.0
PYH2_k127_1980679_8 Protein of unknown function (DUF998) - - - 0.0000008284 57.0
PYH2_k127_1980679_9 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00003019 51.0
PYH2_k127_1986475_0 Dihydroxyacetone kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 348.0
PYH2_k127_1986475_1 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004606 277.0
PYH2_k127_1986475_2 dihydroxyacetone kinase K05879 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 0.0000000162 59.0
PYH2_k127_1996024_0 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 468.0
PYH2_k127_1996024_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 338.0
PYH2_k127_1996024_10 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000002236 112.0
PYH2_k127_1996024_11 Transcriptional regulator K11924 - - 0.00000001304 59.0
PYH2_k127_1996024_13 - - - - 0.00003883 50.0
PYH2_k127_1996024_2 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 304.0
PYH2_k127_1996024_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
PYH2_k127_1996024_4 ABC transporter (ATP-binding protein)-putative sodium extrusion ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
PYH2_k127_1996024_5 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000003758 239.0
PYH2_k127_1996024_6 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000005175 205.0
PYH2_k127_1996024_7 PFAM ABC-2 type transporter K09696 - - 0.000000000000000000000000000000000000000005579 169.0
PYH2_k127_1996024_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000183 146.0
PYH2_k127_1996024_9 DHHA1 domain K07463 - - 0.000000000000000000000000000000004084 141.0
PYH2_k127_2033447_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
PYH2_k127_2033447_1 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000001069 134.0
PYH2_k127_2033447_2 transcription regulator, ArsR family - - - 0.000000003845 63.0
PYH2_k127_2042268_0 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 457.0
PYH2_k127_2042268_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 321.0
PYH2_k127_2042268_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 299.0
PYH2_k127_2042268_3 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007873 276.0
PYH2_k127_2042268_4 PFAM Basic membrane lipoprotein K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004112 258.0
PYH2_k127_2042268_5 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
PYH2_k127_2042268_6 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000006185 221.0
PYH2_k127_2042268_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000009031 151.0
PYH2_k127_2042268_8 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000001056 85.0
PYH2_k127_2042268_9 Belongs to the UPF0235 family K09131 - - 0.00000000185 63.0
PYH2_k127_2045740_0 cobalamin binding K21089,K21972,K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 319.0
PYH2_k127_2045740_1 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 289.0
PYH2_k127_2045740_2 Cytochrome c - - - 0.000000000000000000000000000000000000001363 156.0
PYH2_k127_2045740_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000007397 100.0
PYH2_k127_2045740_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000006819 90.0
PYH2_k127_2064003_0 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000004804 57.0
PYH2_k127_210918_0 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 2.755e-209 675.0
PYH2_k127_210918_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 588.0
PYH2_k127_210918_10 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000003627 208.0
PYH2_k127_210918_11 Peptidase M28 - - - 0.00000000000000000000000000000000000000003058 171.0
PYH2_k127_210918_12 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000005061 149.0
PYH2_k127_210918_13 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000006498 159.0
PYH2_k127_210918_14 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000009999 147.0
PYH2_k127_210918_15 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000008514 103.0
PYH2_k127_210918_16 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.000000008726 57.0
PYH2_k127_210918_17 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.0000002051 59.0
PYH2_k127_210918_18 - - - - 0.00008333 51.0
PYH2_k127_210918_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 434.0
PYH2_k127_210918_3 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 308.0
PYH2_k127_210918_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006899 263.0
PYH2_k127_210918_5 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002098 257.0
PYH2_k127_210918_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
PYH2_k127_210918_7 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000005025 219.0
PYH2_k127_210918_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000883 205.0
PYH2_k127_210918_9 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001784 199.0
PYH2_k127_2120677_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 334.0
PYH2_k127_2120677_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 313.0
PYH2_k127_2120677_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.0000000000000000000000000000000000000000000000000005509 192.0
PYH2_k127_2120677_3 Domain of unknown function (DUF4915) - - - 0.0000000000000000000000000000000000002635 155.0
PYH2_k127_2132822_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000001127 185.0
PYH2_k127_2132822_1 Nitroreductase family - - - 0.000000000000000000000000000000000000001044 155.0
PYH2_k127_2132822_2 - - - - 0.000000000001423 71.0
PYH2_k127_2173909_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 522.0
PYH2_k127_2173909_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 480.0
PYH2_k127_2173909_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000585 267.0
PYH2_k127_2173909_3 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000001857 155.0
PYH2_k127_2173909_4 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000001388 76.0
PYH2_k127_2176331_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000003817 218.0
PYH2_k127_225050_0 Psort location Cytoplasmic, score 8.87 K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 331.0
PYH2_k127_225050_1 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 326.0
PYH2_k127_225050_10 - - - - 0.000000000000000001109 90.0
PYH2_k127_225050_11 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001093 80.0
PYH2_k127_225050_12 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000008631 57.0
PYH2_k127_225050_13 transferase activity, transferring glycosyl groups - - - 0.000000009802 61.0
PYH2_k127_225050_14 RNA-binding protein K07574 - - 0.0000002204 58.0
PYH2_k127_225050_2 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000000000000000000002709 226.0
PYH2_k127_225050_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008811 202.0
PYH2_k127_225050_4 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000006058 176.0
PYH2_k127_225050_5 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000000008243 179.0
PYH2_k127_225050_6 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000009925 161.0
PYH2_k127_225050_7 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000001981 130.0
PYH2_k127_225050_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000002788 100.0
PYH2_k127_225050_9 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000002015 98.0
PYH2_k127_2278651_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 316.0
PYH2_k127_2278651_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000539 247.0
PYH2_k127_2288277_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.619e-194 616.0
PYH2_k127_2288277_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 485.0
PYH2_k127_2288277_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000005535 171.0
PYH2_k127_2288277_11 DNA polymerase Ligase (LigD) - - - 0.00000000000000000000000000000000000000000000374 166.0
PYH2_k127_2288277_12 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000001157 137.0
PYH2_k127_2288277_13 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K20203 - 1.8.1.19 0.00000000000000000000000000000004806 127.0
PYH2_k127_2288277_14 - - - - 0.000000000000000000000000000006561 126.0
PYH2_k127_2288277_15 Flavodoxin - - - 0.000000000000000000004484 100.0
PYH2_k127_2288277_16 Acyltransferase family - - - 0.0000000000013 70.0
PYH2_k127_2288277_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000001619 63.0
PYH2_k127_2288277_18 Hsp20/alpha crystallin family K13993 - - 0.00000002877 61.0
PYH2_k127_2288277_2 small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
PYH2_k127_2288277_3 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 363.0
PYH2_k127_2288277_4 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 366.0
PYH2_k127_2288277_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 348.0
PYH2_k127_2288277_6 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 343.0
PYH2_k127_2288277_7 peptidase activity K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 320.0
PYH2_k127_2288277_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000001043 246.0
PYH2_k127_2288277_9 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000003562 185.0
PYH2_k127_2289043_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.228e-287 898.0
PYH2_k127_2289043_1 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 2.75e-198 630.0
PYH2_k127_2289043_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000005049 240.0
PYH2_k127_2289043_11 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000001 210.0
PYH2_k127_2289043_12 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000002579 211.0
PYH2_k127_2289043_13 COG1290 Cytochrome b subunit of the bc complex - - - 0.00000000000000000000000000000000000000000000000000000905 208.0
PYH2_k127_2289043_14 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000001087 205.0
PYH2_k127_2289043_15 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000005833 169.0
PYH2_k127_2289043_16 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000001607 167.0
PYH2_k127_2289043_17 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000009512 139.0
PYH2_k127_2289043_18 - - - - 0.0000000000000000000000000000000078 133.0
PYH2_k127_2289043_19 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000002926 121.0
PYH2_k127_2289043_2 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 427.0
PYH2_k127_2289043_20 Transcription elongation factor - - - 0.00000000000000000001636 97.0
PYH2_k127_2289043_21 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000001014 89.0
PYH2_k127_2289043_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000556 84.0
PYH2_k127_2289043_23 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000009308 76.0
PYH2_k127_2289043_24 - - - - 0.00000009385 57.0
PYH2_k127_2289043_25 - - - - 0.000001851 52.0
PYH2_k127_2289043_3 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 431.0
PYH2_k127_2289043_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 399.0
PYH2_k127_2289043_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 316.0
PYH2_k127_2289043_6 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001864 287.0
PYH2_k127_2289043_7 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 272.0
PYH2_k127_2289043_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001033 264.0
PYH2_k127_2289043_9 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000194 248.0
PYH2_k127_2331674_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 412.0
PYH2_k127_2331674_1 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 312.0
PYH2_k127_2331674_2 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002426 265.0
PYH2_k127_2331674_3 - - - - 0.00000000000000000000000000000000000000000000000000102 192.0
PYH2_k127_2331674_4 amino acid - - - 0.00000000000000000000000000000000000001603 162.0
PYH2_k127_2331674_5 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000009206 75.0
PYH2_k127_2331674_6 converts alpha-aldose to the beta-anomer - - - 0.0000000002502 65.0
PYH2_k127_235871_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 577.0
PYH2_k127_235871_1 arginine decarboxylase activity K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000292 248.0
PYH2_k127_235871_2 PFAM Threonyl alanyl tRNA synthetase, SAD K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000004147 229.0
PYH2_k127_235871_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000008669 222.0
PYH2_k127_235871_4 cellular alkane metabolic process K16176 - 2.1.1.248 0.000000000000000000000000000000000000000000000000000000000001961 229.0
PYH2_k127_235871_5 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000158 181.0
PYH2_k127_235871_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000138 174.0
PYH2_k127_235871_7 Sugar (and other) transporter - - - 0.0000000000000000000000001388 120.0
PYH2_k127_235871_8 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000004363 77.0
PYH2_k127_235871_9 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000002625 74.0
PYH2_k127_2432121_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.0 1262.0
PYH2_k127_2432121_1 PFAM amino acid permease-associated region K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 559.0
PYH2_k127_2432121_10 Putative tRNA binding domain - - - 0.000000000000008515 75.0
PYH2_k127_2432121_11 AsnC family - - - 0.0002582 46.0
PYH2_k127_2432121_2 PFAM photosystem I assembly BtpA K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 376.0
PYH2_k127_2432121_3 ABC-type transport system, involved in lipoprotein release, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000403 274.0
PYH2_k127_2432121_4 PFAM ABC transporter K02003,K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
PYH2_k127_2432121_5 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 273.0
PYH2_k127_2432121_6 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000007152 211.0
PYH2_k127_2432121_7 Domain of unknown function (DUF4872) - - - 0.0000000000000000000000000000000000000000000000000007953 197.0
PYH2_k127_2432121_8 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000178 208.0
PYH2_k127_2432121_9 pfkB family carbohydrate kinase - - - 0.00000000000000000001169 102.0
PYH2_k127_2445821_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.343e-218 691.0
PYH2_k127_2445821_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 407.0
PYH2_k127_2445821_10 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000002265 186.0
PYH2_k127_2445821_11 PFAM Pyruvate K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000009436 181.0
PYH2_k127_2445821_12 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000009602 176.0
PYH2_k127_2445821_13 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000001781 79.0
PYH2_k127_2445821_14 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000005081 79.0
PYH2_k127_2445821_15 HNH nucleases - - - 0.000003976 53.0
PYH2_k127_2445821_16 ThiS family K03636 - - 0.000007211 52.0
PYH2_k127_2445821_17 Limonene-1,2-epoxide hydrolase - - - 0.00001613 53.0
PYH2_k127_2445821_18 - - - - 0.00002357 51.0
PYH2_k127_2445821_2 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 384.0
PYH2_k127_2445821_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
PYH2_k127_2445821_4 ferredoxin oxidoreductase, subunit beta K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 335.0
PYH2_k127_2445821_5 tripeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 317.0
PYH2_k127_2445821_6 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003131 276.0
PYH2_k127_2445821_7 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000001103 260.0
PYH2_k127_2445821_8 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000001638 233.0
PYH2_k127_2445821_9 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000004103 207.0
PYH2_k127_2699239_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 368.0
PYH2_k127_2699239_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 361.0
PYH2_k127_2699239_2 Histidine kinase - - - 0.0000002878 63.0
PYH2_k127_2711677_0 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 522.0
PYH2_k127_2711677_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 432.0
PYH2_k127_2711677_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 328.0
PYH2_k127_2711677_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 299.0
PYH2_k127_2711677_4 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.000000000000000000000000000000000000000000001972 173.0
PYH2_k127_2711677_5 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000008007 108.0
PYH2_k127_2763067_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 1.209e-222 699.0
PYH2_k127_2763067_1 Coenzyme F420-reducing hydrogenase, gamma subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000003268 243.0
PYH2_k127_2764283_0 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
PYH2_k127_2764283_1 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 397.0
PYH2_k127_2764283_10 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000006967 200.0
PYH2_k127_2764283_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH2_k127_2764283_12 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000001416 186.0
PYH2_k127_2764283_13 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000085 171.0
PYH2_k127_2764283_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001061 174.0
PYH2_k127_2764283_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000001289 170.0
PYH2_k127_2764283_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000004072 146.0
PYH2_k127_2764283_17 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000001973 144.0
PYH2_k127_2764283_18 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000005464 141.0
PYH2_k127_2764283_19 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000296 128.0
PYH2_k127_2764283_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 404.0
PYH2_k127_2764283_20 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001726 117.0
PYH2_k127_2764283_21 ribosomal protein K02912 - - 0.00000000000000000000000006229 113.0
PYH2_k127_2764283_22 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005618 108.0
PYH2_k127_2764283_23 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002283 98.0
PYH2_k127_2764283_24 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000003419 99.0
PYH2_k127_2764283_25 - - - - 0.00000000000000000000344 101.0
PYH2_k127_2764283_26 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002769 93.0
PYH2_k127_2764283_27 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000006558 88.0
PYH2_k127_2764283_28 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000000001592 83.0
PYH2_k127_2764283_29 DKCLD (NUC011) domain K03177,K11131 - 5.4.99.25 0.0000000000000001886 82.0
PYH2_k127_2764283_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 312.0
PYH2_k127_2764283_30 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.0000000000000007126 89.0
PYH2_k127_2764283_31 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000007745 74.0
PYH2_k127_2764283_32 COG1522 Transcriptional regulators - - - 0.0000000000003451 73.0
PYH2_k127_2764283_33 Integral membrane protein DUF106 - - - 0.00000002113 62.0
PYH2_k127_2764283_4 Belongs to the peptidase M50B family - GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 307.0
PYH2_k127_2764283_5 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001102 278.0
PYH2_k127_2764283_6 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 270.0
PYH2_k127_2764283_7 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007789 259.0
PYH2_k127_2764283_8 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004585 254.0
PYH2_k127_2764283_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002664 201.0
PYH2_k127_2788973_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 2.448e-209 664.0
PYH2_k127_2788973_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 512.0
PYH2_k127_2788973_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
PYH2_k127_2788973_3 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000112 73.0
PYH2_k127_2788973_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000002318 72.0
PYH2_k127_2788973_5 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0008835 45.0
PYH2_k127_2826045_0 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 389.0
PYH2_k127_2826045_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 372.0
PYH2_k127_2826045_11 PFAM Dak phosphatase K05879 - 2.7.1.121 0.00000000001157 74.0
PYH2_k127_2826045_12 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000001312 70.0
PYH2_k127_2826045_13 Maintenance of mitochondrial structure and function K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000001864 67.0
PYH2_k127_2826045_14 Belongs to the UPF0200 family - - - 0.00000006263 54.0
PYH2_k127_2826045_15 Flavodoxin - - - 0.00001405 51.0
PYH2_k127_2826045_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 338.0
PYH2_k127_2826045_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 325.0
PYH2_k127_2826045_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 322.0
PYH2_k127_2826045_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000001415 200.0
PYH2_k127_2826045_6 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000002547 190.0
PYH2_k127_2826045_7 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000003218 175.0
PYH2_k127_2826045_8 Penicillin V acylase and related amidases K01442 - 3.5.1.24 0.000000000000000000000000000000000000000001434 161.0
PYH2_k127_2826045_9 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000001808 93.0
PYH2_k127_2844830_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 580.0
PYH2_k127_2844830_1 alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 533.0
PYH2_k127_2844830_10 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
PYH2_k127_2844830_11 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000001908 237.0
PYH2_k127_2844830_12 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005058 231.0
PYH2_k127_2844830_13 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
PYH2_k127_2844830_14 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000001422 221.0
PYH2_k127_2844830_15 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000006857 213.0
PYH2_k127_2844830_16 - - - - 0.000000000000000000000000000000000000000000000000000015 198.0
PYH2_k127_2844830_17 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000001061 194.0
PYH2_k127_2844830_18 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000002713 199.0
PYH2_k127_2844830_19 - - - - 0.000000000000000000000000000000000000000000000000009014 190.0
PYH2_k127_2844830_2 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 398.0
PYH2_k127_2844830_20 amino acid - - - 0.0000000000000000000000000000000000000000000000009862 196.0
PYH2_k127_2844830_21 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.00000000000000000000000000000000000000004094 164.0
PYH2_k127_2844830_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000000000009018 140.0
PYH2_k127_2844830_23 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000001193 134.0
PYH2_k127_2844830_24 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000002256 130.0
PYH2_k127_2844830_25 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000004943 110.0
PYH2_k127_2844830_26 PFAM NurA domain - - - 0.0000000000000000002249 100.0
PYH2_k127_2844830_27 PFAM Radical SAM domain protein - - - 0.0000000000000000002499 99.0
PYH2_k127_2844830_29 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000001139 87.0
PYH2_k127_2844830_3 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 390.0
PYH2_k127_2844830_30 RNA binding K07581 - - 0.000000000009621 72.0
PYH2_k127_2844830_31 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000001629 70.0
PYH2_k127_2844830_32 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000006051 66.0
PYH2_k127_2844830_33 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000002049 64.0
PYH2_k127_2844830_34 PFAM Major Facilitator Superfamily - - - 0.00000003381 65.0
PYH2_k127_2844830_35 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00007813 49.0
PYH2_k127_2844830_36 Transposase IS116/IS110/IS902 family - - - 0.00009176 48.0
PYH2_k127_2844830_4 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 327.0
PYH2_k127_2844830_5 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 321.0
PYH2_k127_2844830_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 298.0
PYH2_k127_2844830_7 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005637 246.0
PYH2_k127_2844830_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000002503 245.0
PYH2_k127_2844830_9 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005565 243.0
PYH2_k127_2853212_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 444.0
PYH2_k127_2853212_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 335.0
PYH2_k127_2853212_2 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 327.0
PYH2_k127_2853212_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000002149 242.0
PYH2_k127_2853212_4 NhaP-type Na H and K H K03316 - - 0.000000000000000000000000000000000000000000000000008617 195.0
PYH2_k127_2853212_5 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000001791 132.0
PYH2_k127_2853212_6 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000008066 91.0
PYH2_k127_2853212_7 amino acid - - - 0.0000000000000000009686 93.0
PYH2_k127_2853212_8 phosphoesterase RecJ domain protein K00970,K00974,K06881 - 2.7.7.19,2.7.7.72,3.1.13.3,3.1.3.7 0.00000000000000001889 88.0
PYH2_k127_2853212_9 Protein of unknown function DUF131 - - - 0.000000003532 62.0
PYH2_k127_2870659_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 9.577e-241 756.0
PYH2_k127_2870659_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 5.433e-213 677.0
PYH2_k127_2870659_10 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000003256 91.0
PYH2_k127_2870659_11 HTH DNA binding domain - - - 0.00000001863 59.0
PYH2_k127_2870659_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.073e-208 661.0
PYH2_k127_2870659_3 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 381.0
PYH2_k127_2870659_4 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 373.0
PYH2_k127_2870659_5 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000292 269.0
PYH2_k127_2870659_6 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000001674 190.0
PYH2_k127_2870659_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000004422 143.0
PYH2_k127_2870659_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000002619 125.0
PYH2_k127_2870659_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000002805 124.0
PYH2_k127_2876021_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.847e-200 646.0
PYH2_k127_2876021_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 597.0
PYH2_k127_2876021_10 AAA family ATPase, CDC48 subfamily K13525 - - 0.0000000000000000000000000000000000003736 162.0
PYH2_k127_2876021_11 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000235 122.0
PYH2_k127_2876021_12 PGAP1-like protein - - - 0.000000000000000000000000007244 111.0
PYH2_k127_2876021_13 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07005 - - 0.0000000000000000000003473 102.0
PYH2_k127_2876021_14 - - - - 0.00000000000001803 78.0
PYH2_k127_2876021_15 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000001237 72.0
PYH2_k127_2876021_16 Subtilase family - - - 0.00000000001343 78.0
PYH2_k127_2876021_17 - - - - 0.000000000121 64.0
PYH2_k127_2876021_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000002929 60.0
PYH2_k127_2876021_19 HNH nucleases - - - 0.00000009256 58.0
PYH2_k127_2876021_2 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 360.0
PYH2_k127_2876021_20 DNA methylase K07316 - 2.1.1.72 0.00009384 47.0
PYH2_k127_2876021_21 Protein of unknown function DUF47 K07220 - - 0.0007093 49.0
PYH2_k127_2876021_3 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 312.0
PYH2_k127_2876021_4 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 282.0
PYH2_k127_2876021_5 PFAM zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000001342 198.0
PYH2_k127_2876021_6 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000002253 195.0
PYH2_k127_2876021_7 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000212 199.0
PYH2_k127_2876021_8 - - - - 0.00000000000000000000000000000000000000006084 168.0
PYH2_k127_2876021_9 Nitroreductase family - - - 0.0000000000000000000000000000000000000001265 159.0
PYH2_k127_2886528_0 Radical SAM domain protein K06937 - - 1.104e-217 687.0
PYH2_k127_2886528_1 Large family of predicted nucleotide-binding domains K06865 - - 3.57e-215 681.0
PYH2_k127_2886528_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
PYH2_k127_2886528_3 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000003928 177.0
PYH2_k127_2886528_4 Protease prsW family - - - 0.0000000000000000000000000000000002154 142.0
PYH2_k127_2886528_5 PFAM Trm112p-like protein - - - 0.0000000000000000000000004908 107.0
PYH2_k127_2886528_6 Dodecin K09165 - - 0.00000000000000003544 83.0
PYH2_k127_2886528_7 PFAM thioesterase superfamily K07107 - - 0.0000000000000001981 84.0
PYH2_k127_2892187_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K18020 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0043546,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363 1.2.5.3,1.2.99.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 535.0
PYH2_k127_2892187_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000003268 257.0
PYH2_k127_2892187_2 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000001478 239.0
PYH2_k127_2892187_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000001892 201.0
PYH2_k127_2892187_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000004231 110.0
PYH2_k127_2892187_5 - - - - 0.00000000000000003571 89.0
PYH2_k127_2892187_6 Membrane complex biogenesis protein, BtpA family K06971 - - 0.000000000008874 66.0
PYH2_k127_2892187_7 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0001101,GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006970,GO:0008150,GO:0009414,GO:0009415,GO:0009628,GO:0009651,GO:0010035,GO:0019904,GO:0042221,GO:0050896,GO:1901700 4.4.1.5 0.00000006143 59.0
PYH2_k127_2892187_8 spore germination - - - 0.000004657 58.0
PYH2_k127_2904205_0 Zinc-binding dehydrogenase K12957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 307.0
PYH2_k127_2904205_1 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000001129 198.0
PYH2_k127_2904205_2 lyase activity - - - 0.00000000000000000000000000000034 128.0
PYH2_k127_2949627_0 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000006745 109.0
PYH2_k127_298105_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 364.0
PYH2_k127_298105_1 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004001 275.0
PYH2_k127_298105_10 Cobalt transport protein K16785 - - 0.0000000000000000000000000001017 125.0
PYH2_k127_298105_11 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000002725 120.0
PYH2_k127_298105_12 COG1522 Transcriptional regulators - - - 0.00000000000000000000011 106.0
PYH2_k127_298105_13 membrane - - - 0.000000000003654 74.0
PYH2_k127_298105_14 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.00000007661 55.0
PYH2_k127_298105_15 - - - - 0.0000178 55.0
PYH2_k127_298105_2 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002003 259.0
PYH2_k127_298105_3 ABC-type cobalt transport system ATPase component K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
PYH2_k127_298105_4 ATP-binding protein K16786 - - 0.0000000000000000000000000000000000000000000000000000000000000005173 230.0
PYH2_k127_298105_5 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000002572 218.0
PYH2_k127_298105_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000007291 179.0
PYH2_k127_298105_8 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000001594 149.0
PYH2_k127_298105_9 Psort location CytoplasmicMembrane, score K16923 - - 0.000000000000000000000000000000001495 136.0
PYH2_k127_3046442_0 TPP binding domain K01652 - 2.2.1.6 7.553e-194 617.0
PYH2_k127_3046442_1 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 506.0
PYH2_k127_3046442_2 PFAM iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 350.0
PYH2_k127_3046442_3 NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000000000000007388 198.0
PYH2_k127_3046442_4 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000009081 152.0
PYH2_k127_3087394_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 474.0
PYH2_k127_3087394_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 300.0
PYH2_k127_3087394_2 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 - 2.1.1.14 0.00000000000000000000000000000000000001775 156.0
PYH2_k127_3087394_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000003698 138.0
PYH2_k127_3092998_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 9.323e-203 641.0
PYH2_k127_3092998_1 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 457.0
PYH2_k127_3092998_2 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
PYH2_k127_3092998_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004962 275.0
PYH2_k127_3092998_4 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000009329 198.0
PYH2_k127_3092998_5 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.00000000000000000000000000000000000003761 150.0
PYH2_k127_3092998_6 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000007026 109.0
PYH2_k127_3127199_0 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 384.0
PYH2_k127_3127199_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
PYH2_k127_3127199_2 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 308.0
PYH2_k127_3127199_3 Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
PYH2_k127_3127199_4 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001725 261.0
PYH2_k127_3127199_5 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000005116 145.0
PYH2_k127_3127199_6 binding-protein-dependent transport systems inner membrane component - - - 0.000000000000000000000002006 113.0
PYH2_k127_3127199_7 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000002174 90.0
PYH2_k127_3134138_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1206.0
PYH2_k127_3134138_1 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 419.0
PYH2_k127_3134138_10 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000006282 222.0
PYH2_k127_3134138_11 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
PYH2_k127_3134138_12 Alcohol dehydrogenase GroES domain protein K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000009226 194.0
PYH2_k127_3134138_13 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000195 165.0
PYH2_k127_3134138_14 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000789 155.0
PYH2_k127_3134138_15 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.000000000000000000000000000000000005328 139.0
PYH2_k127_3134138_16 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000001882 143.0
PYH2_k127_3134138_17 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000001884 130.0
PYH2_k127_3134138_18 - - - - 0.00000000000000000000000278 108.0
PYH2_k127_3134138_19 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000007784 104.0
PYH2_k127_3134138_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 422.0
PYH2_k127_3134138_20 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000000000004105 101.0
PYH2_k127_3134138_21 Universal stress protein - - - 0.0000000000000000002224 93.0
PYH2_k127_3134138_22 Leucyl aminopeptidase (Aminopeptidase t) K19689 - - 0.000000000000000002467 97.0
PYH2_k127_3134138_23 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000002755 94.0
PYH2_k127_3134138_25 WD-40 repeat - - - 0.000001877 61.0
PYH2_k127_3134138_26 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.000004436 49.0
PYH2_k127_3134138_27 - - - - 0.00005384 51.0
PYH2_k127_3134138_28 PRC-barrel domain - - - 0.00005738 49.0
PYH2_k127_3134138_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 392.0
PYH2_k127_3134138_4 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
PYH2_k127_3134138_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006388 277.0
PYH2_k127_3134138_6 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003503 278.0
PYH2_k127_3134138_7 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008052 267.0
PYH2_k127_3134138_8 UV damage endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 252.0
PYH2_k127_3134138_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000001127 231.0
PYH2_k127_3146171_0 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 438.0
PYH2_k127_3146171_1 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000001712 164.0
PYH2_k127_3146171_2 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.00000000000000000000002171 109.0
PYH2_k127_3146171_3 PFAM beta-lactamase domain protein - - - 0.000000000005141 66.0
PYH2_k127_3146171_4 PFAM YHS domain - - - 0.00000000001548 65.0
PYH2_k127_3146171_5 transcriptional regulator K13652 - - 0.00000000008634 68.0
PYH2_k127_3146171_6 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000006053 55.0
PYH2_k127_3146171_7 - - - - 0.000004834 56.0
PYH2_k127_3146171_8 Glutaredoxin-like domain (DUF836) - - - 0.0001609 47.0
PYH2_k127_3146171_9 Copper-transporting ATPase 2 K17686 GO:0000041,GO:0000139,GO:0000166,GO:0002164,GO:0003674,GO:0003824,GO:0004008,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005783,GO:0005794,GO:0005802,GO:0005886,GO:0005887,GO:0005911,GO:0005923,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006874,GO:0006875,GO:0006878,GO:0006882,GO:0007275,GO:0007589,GO:0007591,GO:0007593,GO:0007595,GO:0007623,GO:0008144,GO:0008150,GO:0008270,GO:0008324,GO:0009719,GO:0009725,GO:0009791,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010043,GO:0010243,GO:0012505,GO:0014070,GO:0014074,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015677,GO:0015680,GO:0016020,GO:0016021,GO:0016323,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019725,GO:0019829,GO:0021700,GO:0022404,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030054,GO:0030554,GO:0030879,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0031984,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032588,GO:0034220,GO:0035434,GO:0035639,GO:0036094,GO:0042221,GO:0042303,GO:0042335,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043296,GO:0043434,GO:0043473,GO:0043492,GO:0043682,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045177,GO:0046683,GO:0046688,GO:0046872,GO:0046873,GO:0046903,GO:0046907,GO:0046914,GO:0046915,GO:0046916,GO:0048066,GO:0048067,GO:0048085,GO:0048471,GO:0048511,GO:0048513,GO:0048731,GO:0048732,GO:0048856,GO:0048878,GO:0050801,GO:0050878,GO:0050896,GO:0051179,GO:0051208,GO:0051234,GO:0051235,GO:0051591,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055069,GO:0055070,GO:0055074,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0065007,GO:0065008,GO:0070160,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071287,GO:0071944,GO:0072503,GO:0072507,GO:0090662,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098791,GO:0098805,GO:0099131,GO:0099132,GO:1901265,GO:1901363,GO:1901652,GO:1901698,GO:1901700,GO:1990637 3.6.3.54 0.0003134 46.0
PYH2_k127_3264050_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 515.0
PYH2_k127_3264050_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 460.0
PYH2_k127_3264050_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 367.0
PYH2_k127_3264050_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
PYH2_k127_3264050_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000003058 192.0
PYH2_k127_3264050_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.000000000000000000000000001253 118.0
PYH2_k127_3264050_6 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.000000000000002548 81.0
PYH2_k127_3264050_7 - - - - 0.00001567 53.0
PYH2_k127_3267550_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 3.945e-205 651.0
PYH2_k127_3267550_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 340.0
PYH2_k127_3267550_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000001275 180.0
PYH2_k127_3267550_3 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.0000000000000000000000000000000000000003012 156.0
PYH2_k127_3267550_4 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.000000000000000000000000000000000000132 148.0
PYH2_k127_3267550_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014,K03055 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000002593 79.0
PYH2_k127_3267550_6 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000002865 67.0
PYH2_k127_3279064_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.286e-245 767.0
PYH2_k127_3279064_1 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 276.0
PYH2_k127_3279064_2 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001664 259.0
PYH2_k127_3279064_3 Zn-dependent hydrolase of the beta-lactamase - - - 0.0000000006684 64.0
PYH2_k127_3338771_0 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.292e-239 757.0
PYH2_k127_3338771_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 8.116e-220 694.0
PYH2_k127_3338771_10 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
PYH2_k127_3338771_11 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000001433 205.0
PYH2_k127_3338771_12 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000002163 195.0
PYH2_k127_3338771_13 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000004973 185.0
PYH2_k127_3338771_14 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000001727 171.0
PYH2_k127_3338771_15 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000004249 146.0
PYH2_k127_3338771_16 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000005251 133.0
PYH2_k127_3338771_17 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000001554 95.0
PYH2_k127_3338771_18 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000776 96.0
PYH2_k127_3338771_19 - - - - 0.00000000005372 66.0
PYH2_k127_3338771_2 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 462.0
PYH2_k127_3338771_20 transferase activity, transferring glycosyl groups - - - 0.000000001278 66.0
PYH2_k127_3338771_21 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0001006 46.0
PYH2_k127_3338771_3 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 362.0
PYH2_k127_3338771_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 355.0
PYH2_k127_3338771_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 336.0
PYH2_k127_3338771_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 306.0
PYH2_k127_3338771_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00175 - 1.2.7.1,1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
PYH2_k127_3338771_8 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001165 260.0
PYH2_k127_3338771_9 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002811 254.0
PYH2_k127_3342962_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
PYH2_k127_3342962_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 420.0
PYH2_k127_3342962_10 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.0000000000000000000000000000009434 123.0
PYH2_k127_3342962_11 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000003315 127.0
PYH2_k127_3342962_12 - - - - 0.00000000000000000000000000004399 126.0
PYH2_k127_3342962_13 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000001914 89.0
PYH2_k127_3342962_14 transporter K07238,K11021,K16267 - - 0.0000000000000002583 88.0
PYH2_k127_3342962_15 - - - - 0.0000000000001897 76.0
PYH2_k127_3342962_16 Domain of unknown function (DUF4382) - - - 0.0000007445 57.0
PYH2_k127_3342962_17 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000001545 57.0
PYH2_k127_3342962_18 - - - - 0.00005258 49.0
PYH2_k127_3342962_2 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 362.0
PYH2_k127_3342962_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
PYH2_k127_3342962_4 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
PYH2_k127_3342962_5 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000001963 182.0
PYH2_k127_3342962_6 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000144 153.0
PYH2_k127_3342962_7 - - - - 0.0000000000000000000000000000000000006795 147.0
PYH2_k127_3342962_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.000000000000000000000000000000004528 134.0
PYH2_k127_3342962_9 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000001459 138.0
PYH2_k127_3375214_0 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 403.0
PYH2_k127_3375214_1 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 360.0
PYH2_k127_3375214_10 methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000009649 190.0
PYH2_k127_3375214_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000001975 179.0
PYH2_k127_3375214_12 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000000007608 174.0
PYH2_k127_3375214_13 membrane - - - 0.0000000000000000000000000000001343 134.0
PYH2_k127_3375214_14 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000002437 133.0
PYH2_k127_3375214_15 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000008982 130.0
PYH2_k127_3375214_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000004394 123.0
PYH2_k127_3375214_17 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000001113 117.0
PYH2_k127_3375214_18 Peptidase C13 family - - - 0.000000000000000000001299 110.0
PYH2_k127_3375214_19 Belongs to the UPF0201 family K09736 - - 0.000000000000000001058 92.0
PYH2_k127_3375214_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 361.0
PYH2_k127_3375214_20 Glycosyltransferase family 87 - - - 0.0000000000000003022 91.0
PYH2_k127_3375214_21 Transcriptional regulator PadR-like family - - - 0.00000000000404 71.0
PYH2_k127_3375214_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001505 65.0
PYH2_k127_3375214_23 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000003555 64.0
PYH2_k127_3375214_24 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00008191 48.0
PYH2_k127_3375214_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000007669 275.0
PYH2_k127_3375214_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000003182 265.0
PYH2_k127_3375214_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009014 243.0
PYH2_k127_3375214_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
PYH2_k127_3375214_7 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003638 234.0
PYH2_k127_3375214_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000002943 219.0
PYH2_k127_3375214_9 Ser thr protein kinase K07176 - - 0.0000000000000000000000000000000000000000000000000000009966 201.0
PYH2_k127_3432256_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 420.0
PYH2_k127_3432256_1 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000002993 151.0
PYH2_k127_3432256_2 Conserved protein implicated in secretion - - - 0.000000000000000000000000000000007299 137.0
PYH2_k127_3432256_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000006912 124.0
PYH2_k127_3432256_4 - - - - 0.0000000000000000002157 97.0
PYH2_k127_3432256_5 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000003269 88.0
PYH2_k127_3432256_6 helix_turn_helix ASNC type - - - 0.00000000009958 71.0
PYH2_k127_3432308_0 Transketolase, central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 355.0
PYH2_k127_3432308_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 338.0
PYH2_k127_3432308_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 290.0
PYH2_k127_3432308_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000001794 253.0
PYH2_k127_3432308_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000334 256.0
PYH2_k127_3432308_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000126 189.0
PYH2_k127_3432308_6 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000006351 135.0
PYH2_k127_3432308_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000002038 59.0
PYH2_k127_3432308_8 Zinc-binding dehydrogenase - - - 0.000000003931 61.0
PYH2_k127_3512243_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 450.0
PYH2_k127_3512243_1 pyruvate decarboxylase activity K04103 - 4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 444.0
PYH2_k127_3512243_2 PFAM peptidase C45 acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000002249 205.0
PYH2_k127_3512243_3 transcriptional - - - 0.000000000000000000000000000003377 122.0
PYH2_k127_3512243_4 - - - - 0.000000004934 63.0
PYH2_k127_3512243_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.000000005257 60.0
PYH2_k127_3529954_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K18020 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0043546,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363 1.2.5.3,1.2.99.8 1.519e-199 646.0
PYH2_k127_3529954_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 493.0
PYH2_k127_3529954_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 452.0
PYH2_k127_3529954_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 409.0
PYH2_k127_3529954_4 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 389.0
PYH2_k127_3529954_5 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000009177 264.0
PYH2_k127_3529954_6 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000001083 213.0
PYH2_k127_3529954_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000002195 165.0
PYH2_k127_3529954_8 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000004241 93.0
PYH2_k127_3529954_9 - - - - 0.0000000000000163 81.0
PYH2_k127_3562202_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 298.0
PYH2_k127_3562202_1 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000369 141.0
PYH2_k127_3562202_2 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000008653 100.0
PYH2_k127_3632744_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000001812 142.0
PYH2_k127_3632744_1 Xylose isomerase-like TIM barrel - - - 0.000000000001039 75.0
PYH2_k127_3632744_2 PFAM Uncharacterised BCR, COG1649 - - - 0.000213 46.0
PYH2_k127_3654632_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 544.0
PYH2_k127_3673560_0 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 567.0
PYH2_k127_3673560_1 xylulokinase activity K11216 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009372,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0042710,GO:0044010,GO:0044237,GO:0044764,GO:0051704,GO:0071518 2.7.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 552.0
PYH2_k127_3673560_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 513.0
PYH2_k127_3673560_3 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 372.0
PYH2_k127_3673560_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
PYH2_k127_3673560_5 Pyridine nucleotide-disulphide oxidoreductase K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.000000000000000000000000000000000000000000000000001415 189.0
PYH2_k127_3673560_6 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.0000000000000000000000000000000001384 144.0
PYH2_k127_3673560_7 HAD-superfamily phosphatase, subfamily IIIC - - - 0.00000000000000000000000000000002809 134.0
PYH2_k127_3673560_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000004607 129.0
PYH2_k127_3673560_9 Transketolase, pyrimidine binding domain K21417 - - 0.0000001528 55.0
PYH2_k127_3676592_0 Thi4 family K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 431.0
PYH2_k127_3676592_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 366.0
PYH2_k127_3676592_2 PFAM MOFRL domain protein K11529 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008887,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0071704,GO:1901564 2.7.1.165 0.00000000000000000000000000000000000000001407 158.0
PYH2_k127_3676592_3 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.000000000000000000000000001634 113.0
PYH2_k127_3778717_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.598e-197 623.0
PYH2_k127_3778717_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 430.0
PYH2_k127_3778717_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
PYH2_k127_3778717_3 Domain of unknown function (DUF4432) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003817 244.0
PYH2_k127_3778717_4 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000006095 239.0
PYH2_k127_3778717_5 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000008163 131.0
PYH2_k127_3778717_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000001232 116.0
PYH2_k127_3778717_7 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00002855 51.0
PYH2_k127_3778717_8 SCP-2 sterol transfer family - - - 0.0004861 48.0
PYH2_k127_3803861_0 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 293.0
PYH2_k127_3803861_1 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000002433 179.0
PYH2_k127_3803861_2 Transketolase K00615 - 2.2.1.1 0.000000000000000008713 85.0
PYH2_k127_3803861_3 Universal stress protein family - - - 0.00000000000006527 74.0
PYH2_k127_3940119_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
PYH2_k127_3940119_1 Xylose isomerase-like TIM barrel K10709 - - 0.00000000000000000000000000000000000000000000006702 179.0
PYH2_k127_3940119_2 PFAM carbohydrate kinase K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.0000000000000000000000000000000000000000000007675 183.0
PYH2_k127_3940119_3 Radical SAM domain protein - - - 0.000000000000000000113 91.0
PYH2_k127_3959339_0 dihydrodipicolinate reductase K03340,K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.16,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
PYH2_k127_3959339_1 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003713 277.0
PYH2_k127_3959339_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000002123 223.0
PYH2_k127_3959339_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000001435 208.0
PYH2_k127_3959339_4 PFAM B12 binding domain - - - 0.00000000000000000000000000000000000000000000000001003 188.0
PYH2_k127_400203_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 503.0
PYH2_k127_400203_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 417.0
PYH2_k127_400203_2 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 361.0
PYH2_k127_400203_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000002293 167.0
PYH2_k127_400203_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000005576 144.0
PYH2_k127_400203_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000005519 115.0
PYH2_k127_4005375_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 497.0
PYH2_k127_4005375_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
PYH2_k127_4005375_3 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000001036 131.0
PYH2_k127_4005375_4 Transcriptional regulator K03524 - 6.3.4.15 0.0000000000000000000000000000003863 133.0
PYH2_k127_4005375_5 Flavodoxin - - - 0.00000000000000000000000000001948 123.0
PYH2_k127_4005375_6 AsnC family K03718 - - 0.00000001399 66.0
PYH2_k127_4025845_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000007814 258.0
PYH2_k127_4025845_1 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004576 207.0
PYH2_k127_4025845_2 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000003615 160.0
PYH2_k127_4025845_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000003417 107.0
PYH2_k127_4025845_4 protein conserved in archaea K09723 - - 0.000002617 57.0
PYH2_k127_4066913_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 428.0
PYH2_k127_4066913_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001516 264.0
PYH2_k127_4091826_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000001462 199.0
PYH2_k127_4091826_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001206 177.0
PYH2_k127_4091826_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000003801 147.0
PYH2_k127_4091826_3 Alcohol dehydrogenase GroES-like domain K00008,K08322 - 1.1.1.14,1.1.1.380 0.0000000000000001071 85.0
PYH2_k127_4152686_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 324.0
PYH2_k127_4152686_2 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000006285 158.0
PYH2_k127_4152686_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000001384 87.0
PYH2_k127_4159415_0 DNA polymerase K02319 - 2.7.7.7 1.633e-242 777.0
PYH2_k127_4159415_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000006315 259.0
PYH2_k127_4159415_10 PFAM CopG domain protein DNA-binding domain protein - - - 0.000000000002538 68.0
PYH2_k127_4159415_11 S25 ribosomal protein K02975 - - 0.00000001294 60.0
PYH2_k127_4159415_12 - - - - 0.000005058 57.0
PYH2_k127_4159415_2 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004897 245.0
PYH2_k127_4159415_3 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000005231 221.0
PYH2_k127_4159415_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH2_k127_4159415_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000007437 211.0
PYH2_k127_4159415_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000008831 194.0
PYH2_k127_4159415_7 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000001936 150.0
PYH2_k127_4159415_8 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000002477 113.0
PYH2_k127_4159415_9 - K09143 - - 0.000000000000000001065 90.0
PYH2_k127_4200834_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 316.0
PYH2_k127_4380180_0 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 434.0
PYH2_k127_4380180_1 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 365.0
PYH2_k127_4380180_10 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.000002134 56.0
PYH2_k127_4380180_2 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 325.0
PYH2_k127_4380180_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
PYH2_k127_4380180_4 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000000000000007731 203.0
PYH2_k127_4380180_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000001944 186.0
PYH2_k127_4380180_6 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000008221 181.0
PYH2_k127_4380180_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000183 162.0
PYH2_k127_4380180_8 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002244 160.0
PYH2_k127_4380180_9 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.000000000000000000000000000000000000001598 160.0
PYH2_k127_4410682_0 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000001211 213.0
PYH2_k127_4410682_1 - - - - 0.000000000000000000000000004251 121.0
PYH2_k127_4454520_0 aminopeptidase activity - - - 0.00000000000003436 81.0
PYH2_k127_4454520_1 Winged helix-turn-helix - - - 0.00002705 49.0
PYH2_k127_4455776_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 580.0
PYH2_k127_4455776_1 Glycine cleavage system P-protein K00281,K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 536.0
PYH2_k127_4455776_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000134 247.0
PYH2_k127_4455776_3 pyridoxamine 5-phosphate - - - 0.000000000000652 75.0
PYH2_k127_4455776_4 Staygreen protein - - - 0.0008326 44.0
PYH2_k127_4581782_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 461.0
PYH2_k127_4581782_1 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000005887 268.0
PYH2_k127_4581782_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000166 162.0
PYH2_k127_4581782_3 DGC domain - - - 0.00000000000000000000000000000000001085 139.0
PYH2_k127_4581782_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000009457 127.0
PYH2_k127_4581782_5 DGC domain - - - 0.000000000000000000000000001513 117.0
PYH2_k127_4581782_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000001837 119.0
PYH2_k127_4581782_7 regulatory protein, arsR K03892 - - 0.00000000000000003243 87.0
PYH2_k127_4584002_0 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 325.0
PYH2_k127_4584002_1 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000003347 188.0
PYH2_k127_4584002_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000767 173.0
PYH2_k127_4584002_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000001407 158.0
PYH2_k127_4584002_4 PFAM THUMP domain protein K06963 - - 0.000000000000000000000000000000000106 141.0
PYH2_k127_4584002_5 protein conserved in archaea - - - 0.000000000000000051 91.0
PYH2_k127_4584002_6 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000005045 77.0
PYH2_k127_4584002_7 KEOPS complex Cgi121-like subunit K09119 - - 0.000000003125 65.0
PYH2_k127_4640644_0 peptide catabolic process K13722 - - 4.359e-242 771.0
PYH2_k127_4640644_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 541.0
PYH2_k127_4640644_10 peptidase U32 - - - 0.00000000000000000006856 91.0
PYH2_k127_4640644_11 Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00002978 52.0
PYH2_k127_4640644_2 P COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 385.0
PYH2_k127_4640644_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 356.0
PYH2_k127_4640644_4 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 323.0
PYH2_k127_4640644_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001855 231.0
PYH2_k127_4640644_6 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000201 177.0
PYH2_k127_4640644_7 amino acid-binding ACT domain protein K07103 - - 0.0000000000000000000000000000000000002777 147.0
PYH2_k127_4640644_8 Fructose-1-6-bisphosphatase, N-terminal domain K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.00000000000000000000000000000000007478 143.0
PYH2_k127_4640644_9 signal transduction protein with CBS domains - - - 0.00000000000000000001379 98.0
PYH2_k127_46548_0 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 612.0
PYH2_k127_46548_1 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 469.0
PYH2_k127_46548_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 337.0
PYH2_k127_46548_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 328.0
PYH2_k127_46548_12 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 319.0
PYH2_k127_46548_13 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 304.0
PYH2_k127_46548_14 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 312.0
PYH2_k127_46548_15 TIGRFAM 2-hydroxy-3-oxopropionate reductase K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 294.0
PYH2_k127_46548_16 Enoyl-(Acyl carrier protein) reductase K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 291.0
PYH2_k127_46548_17 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 299.0
PYH2_k127_46548_18 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001297 290.0
PYH2_k127_46548_19 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008246 264.0
PYH2_k127_46548_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 408.0
PYH2_k127_46548_20 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000005415 267.0
PYH2_k127_46548_21 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000002617 248.0
PYH2_k127_46548_22 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000004297 255.0
PYH2_k127_46548_23 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
PYH2_k127_46548_24 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000004454 238.0
PYH2_k127_46548_25 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000008869 217.0
PYH2_k127_46548_26 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000116 215.0
PYH2_k127_46548_27 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000002264 209.0
PYH2_k127_46548_28 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001003 195.0
PYH2_k127_46548_29 - - - - 0.000000000000000000000000000000000000000000000000000003502 199.0
PYH2_k127_46548_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 409.0
PYH2_k127_46548_30 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000002773 197.0
PYH2_k127_46548_31 - - - - 0.0000000000000000000000000000000000000000000000000004749 194.0
PYH2_k127_46548_32 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001999 192.0
PYH2_k127_46548_33 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K14084 - - 0.000000000000000000000000000000000000000000000000008542 188.0
PYH2_k127_46548_34 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000001709 186.0
PYH2_k127_46548_35 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000002098 171.0
PYH2_k127_46548_36 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000003548 152.0
PYH2_k127_46548_37 amino acid - - - 0.00000000000000000000000000000000000007546 161.0
PYH2_k127_46548_38 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000003624 130.0
PYH2_k127_46548_39 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000256 115.0
PYH2_k127_46548_4 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 396.0
PYH2_k127_46548_40 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000001976 91.0
PYH2_k127_46548_41 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000001832 80.0
PYH2_k127_46548_42 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000007913 76.0
PYH2_k127_46548_43 structural constituent of ribosome K02978 - - 0.0000000000003049 72.0
PYH2_k127_46548_44 PFAM Cupin - - - 0.00000009913 58.0
PYH2_k127_46548_45 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005777,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006089,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009507,GO:0009526,GO:0009536,GO:0009628,GO:0009651,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0019863,GO:0019865,GO:0031967,GO:0031975,GO:0032787,GO:0042180,GO:0042182,GO:0042221,GO:0042579,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046185,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0051596,GO:0061727,GO:0071704,GO:0071944,GO:1901575,GO:1901615 4.4.1.5 0.0000002186 59.0
PYH2_k127_46548_46 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.000002281 53.0
PYH2_k127_46548_47 - - - - 0.0001368 47.0
PYH2_k127_46548_48 Luciferase-like monooxygenase K14728 - - 0.0006633 47.0
PYH2_k127_46548_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 390.0
PYH2_k127_46548_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 362.0
PYH2_k127_46548_7 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 355.0
PYH2_k127_46548_8 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 338.0
PYH2_k127_46548_9 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
PYH2_k127_4680364_0 - - - - 0.0000000000000000000000001372 110.0
PYH2_k127_4680364_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000004136 87.0
PYH2_k127_4680364_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000002719 80.0
PYH2_k127_4680364_3 GlcNAc-PI de-N-acetylase - - - 0.00000001451 57.0
PYH2_k127_4726210_0 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 495.0
PYH2_k127_4726210_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 464.0
PYH2_k127_4726210_2 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000002608 174.0
PYH2_k127_4726210_3 Peptidase family M48 - - - 0.0000000000000000001118 100.0
PYH2_k127_4726210_4 4Fe-4S double cluster binding domain - - - 0.000000000007362 75.0
PYH2_k127_4759021_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 8.955e-194 618.0
PYH2_k127_4759021_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 367.0
PYH2_k127_4759021_10 Transcriptional regulators - - - 0.0000000005655 69.0
PYH2_k127_4759021_11 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000002909 51.0
PYH2_k127_4759021_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 364.0
PYH2_k127_4759021_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
PYH2_k127_4759021_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000004469 250.0
PYH2_k127_4759021_5 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000001742 217.0
PYH2_k127_4759021_6 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000004905 159.0
PYH2_k127_4759021_7 Universal stress protein - - - 0.000000000000000000000001799 108.0
PYH2_k127_4759021_8 ABC-2 type transporter - - - 0.000000000000000003588 94.0
PYH2_k127_4759021_9 glycolate biosynthetic process - - - 0.00000000000000003094 90.0
PYH2_k127_4775593_0 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000001525 102.0
PYH2_k127_4775593_1 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.0000000000000006957 84.0
PYH2_k127_4777262_0 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000001499 209.0
PYH2_k127_4777262_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000002173 136.0
PYH2_k127_4777262_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000569 114.0
PYH2_k127_4777262_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000003598 89.0
PYH2_k127_4777262_4 Hemerythrin HHE cation binding domain K16276 - - 0.0001674 47.0
PYH2_k127_4798958_0 selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005349 251.0
PYH2_k127_4846276_0 COG2015 Alkyl sulfatase and related hydrolases - - - 2.742e-292 909.0
PYH2_k127_4846276_1 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 351.0
PYH2_k127_4846276_2 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 313.0
PYH2_k127_4846276_3 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007346 284.0
PYH2_k127_4846276_4 YHS domain K00441 - 1.12.98.1 0.000000001316 64.0
PYH2_k127_4867799_0 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
PYH2_k127_4867799_1 Belongs to the RimK family K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000009789 226.0
PYH2_k127_4867799_2 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000001888 171.0
PYH2_k127_4867799_3 F420-0:Gamma-glutamyl ligase - - - 0.00000000000000000000000000000000000000008797 162.0
PYH2_k127_4867799_4 DNA polymerase beta domain protein region K09717 - - 0.0000000000000000000000000000000000000004095 164.0
PYH2_k127_4868671_0 Psort location CytoplasmicMembrane, score K17686 - 3.6.3.54 7.496e-207 664.0
PYH2_k127_4868671_1 Alpha beta hydrolase - - - 0.00000003653 58.0
PYH2_k127_4876583_0 Beta-Casp domain K07041 - - 2.726e-214 683.0
PYH2_k127_4876583_1 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 367.0
PYH2_k127_4876583_10 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004645 190.0
PYH2_k127_4876583_11 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000132 188.0
PYH2_k127_4876583_12 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000002678 181.0
PYH2_k127_4876583_13 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000001191 164.0
PYH2_k127_4876583_14 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000002137 136.0
PYH2_k127_4876583_15 PFAM Translin K07477 - - 0.00000000000000000000000002583 116.0
PYH2_k127_4876583_16 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.0000000000000000000000001064 114.0
PYH2_k127_4876583_17 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001657 100.0
PYH2_k127_4876583_18 snRNP Sm proteins K04796 - - 0.00000000000000000000002575 101.0
PYH2_k127_4876583_19 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000001216 104.0
PYH2_k127_4876583_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 363.0
PYH2_k127_4876583_20 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000006411 85.0
PYH2_k127_4876583_21 Pfam:DUF552 K09152 - - 0.0000000000000007111 81.0
PYH2_k127_4876583_22 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.000001625 53.0
PYH2_k127_4876583_23 Belongs to the UPF0248 family K09715 - - 0.0000168 51.0
PYH2_k127_4876583_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 349.0
PYH2_k127_4876583_4 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000001068 236.0
PYH2_k127_4876583_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
PYH2_k127_4876583_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH2_k127_4876583_7 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
PYH2_k127_4876583_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000002113 208.0
PYH2_k127_4876583_9 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
PYH2_k127_4889618_0 PFAM Prolyl oligopeptidase family - - - 1.173e-271 849.0
PYH2_k127_4889618_1 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 419.0
PYH2_k127_4889618_2 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 312.0
PYH2_k127_4889618_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
PYH2_k127_4889618_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000007318 188.0
PYH2_k127_4889618_5 - - - - 0.000000000000000000000000000000000000000000000001428 187.0
PYH2_k127_4889618_6 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000002647 166.0
PYH2_k127_4889618_7 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000003871 166.0
PYH2_k127_4895136_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 290.0
PYH2_k127_4895136_1 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000001318 170.0
PYH2_k127_4895136_2 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000009053 113.0
PYH2_k127_4895136_3 DJ-1/PfpI family - - - 0.00000000000000000000000004059 115.0
PYH2_k127_4895136_4 - - - - 0.00000000000003408 76.0
PYH2_k127_4994632_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000005301 236.0
PYH2_k127_4994632_1 - - - - 0.00000000000000000000000000000000000000000000000001212 190.0
PYH2_k127_4994632_2 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000148 184.0
PYH2_k127_4994632_3 PFAM Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000004587 132.0
PYH2_k127_4994632_4 cyclic nucleotide binding K09766,K10914 - - 0.000000000000000000000000224 110.0
PYH2_k127_4994632_5 - - - - 0.00000000000000000003473 93.0
PYH2_k127_4994632_6 F420-dependent - - - 0.0000000588 56.0
PYH2_k127_5058933_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 389.0
PYH2_k127_5058933_1 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 377.0
PYH2_k127_5058933_10 formylmethanofuran dehydrogenase, subunit E - - - 0.000000000000000001447 91.0
PYH2_k127_5058933_11 ECF-type riboflavin transporter, S component K16923 - - 0.0005426 49.0
PYH2_k127_5058933_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 371.0
PYH2_k127_5058933_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 341.0
PYH2_k127_5058933_4 acetamidase formamidase K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000103 291.0
PYH2_k127_5058933_5 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000009746 272.0
PYH2_k127_5058933_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000009202 205.0
PYH2_k127_5058933_7 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000001109 143.0
PYH2_k127_5058933_8 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000001019 136.0
PYH2_k127_5058933_9 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000001192 107.0
PYH2_k127_5185645_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 375.0
PYH2_k127_5185645_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000002391 71.0
PYH2_k127_5201811_0 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 571.0
PYH2_k127_5286741_0 Aldehyde ferredoxin K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 540.0
PYH2_k127_5286741_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 526.0
PYH2_k127_5286741_10 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000173 102.0
PYH2_k127_5286741_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000001933 98.0
PYH2_k127_5286741_12 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000009913 75.0
PYH2_k127_5286741_13 Psort location CytoplasmicMembrane, score K16927 - - 0.0000000004585 68.0
PYH2_k127_5286741_14 Belongs to the 5'(3')-deoxyribonucleotidase family K05967 - - 0.0000006313 59.0
PYH2_k127_5286741_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 383.0
PYH2_k127_5286741_3 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 335.0
PYH2_k127_5286741_4 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 299.0
PYH2_k127_5286741_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007077 288.0
PYH2_k127_5286741_6 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000138 252.0
PYH2_k127_5286741_7 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000006206 238.0
PYH2_k127_5286741_8 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
PYH2_k127_5286741_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000001175 157.0
PYH2_k127_5420716_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 1.157e-301 961.0
PYH2_k127_5420716_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 540.0
PYH2_k127_5420716_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 282.0
PYH2_k127_5420716_11 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003641 218.0
PYH2_k127_5420716_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000004204 213.0
PYH2_k127_5420716_13 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000005487 204.0
PYH2_k127_5420716_14 PFAM HhH-GPD family protein K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000001656 173.0
PYH2_k127_5420716_15 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000002439 164.0
PYH2_k127_5420716_16 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000002274 164.0
PYH2_k127_5420716_17 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000002126 153.0
PYH2_k127_5420716_18 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000004398 147.0
PYH2_k127_5420716_19 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000009157 104.0
PYH2_k127_5420716_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 462.0
PYH2_k127_5420716_20 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.0000000000000000000002154 102.0
PYH2_k127_5420716_21 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000002465 105.0
PYH2_k127_5420716_22 Protein of unknown function (DUF3795) - - - 0.000000000000000000001964 99.0
PYH2_k127_5420716_23 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000004335 96.0
PYH2_k127_5420716_24 Transcriptional regulator K11924 - - 0.0000000000000005093 84.0
PYH2_k127_5420716_25 - - - - 0.000000000000001444 77.0
PYH2_k127_5420716_26 - - - - 0.00000000000005045 77.0
PYH2_k127_5420716_27 Membrane protein-like protein - - - 0.0000000000453 72.0
PYH2_k127_5420716_28 PFAM Transcription elongation factor Elf1 like - - - 0.0000000001388 65.0
PYH2_k127_5420716_3 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 422.0
PYH2_k127_5420716_30 Sec61beta family - - - 0.0000000489 56.0
PYH2_k127_5420716_31 Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins. K06874 - - 0.00000006309 59.0
PYH2_k127_5420716_32 - - - - 0.00001286 55.0
PYH2_k127_5420716_33 Protein of unknown function (DUF2721) - - - 0.0001502 50.0
PYH2_k127_5420716_34 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0001727 48.0
PYH2_k127_5420716_4 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 406.0
PYH2_k127_5420716_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
PYH2_k127_5420716_6 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 344.0
PYH2_k127_5420716_7 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 342.0
PYH2_k127_5420716_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 328.0
PYH2_k127_5420716_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 293.0
PYH2_k127_5518687_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 2.184e-277 868.0
PYH2_k127_5518687_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000006764 201.0
PYH2_k127_5549789_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000005467 200.0
PYH2_k127_5549789_1 PUA domain containing protein K07398 - - 0.000000000000000000000000000000009162 133.0
PYH2_k127_5549789_2 - - - - 0.000000000000000000000000001436 115.0
PYH2_k127_5549789_3 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000001735 98.0
PYH2_k127_5549789_4 Transcriptional regulator K07332 - - 0.00000000000000000000754 101.0
PYH2_k127_5549789_5 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000001898 84.0
PYH2_k127_5549789_6 Sap, sulfolipid-1-addressing protein - - - 0.0000000000004742 77.0
PYH2_k127_5573676_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.656e-204 650.0
PYH2_k127_5573676_1 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000037 192.0
PYH2_k127_5573676_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000003948 192.0
PYH2_k127_5573676_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000003775 177.0
PYH2_k127_5573676_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000001869 101.0
PYH2_k127_5573676_5 Domain of unknown function (DUF1844) - - - 0.00000001108 62.0
PYH2_k127_5573676_6 FMN binding K03809 - 1.6.5.2 0.0000001174 59.0
PYH2_k127_5634001_0 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001609 239.0
PYH2_k127_5634001_1 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000003123 218.0
PYH2_k127_5634001_2 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000002298 99.0
PYH2_k127_5634001_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000002525 68.0
PYH2_k127_5639636_0 melibiose metabolic process K01222,K07406 - 3.2.1.22,3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 377.0
PYH2_k127_5639636_1 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000006131 254.0
PYH2_k127_5639636_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000001119 123.0
PYH2_k127_5639636_4 glucosylceramidase activity - - - 0.0009772 47.0
PYH2_k127_5675087_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K00087 - 1.17.1.4 1.245e-240 766.0
PYH2_k127_5675087_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000196 255.0
PYH2_k127_5675087_10 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000001097 66.0
PYH2_k127_5675087_11 PFAM thiamineS protein K03636 - - 0.00000007408 57.0
PYH2_k127_5675087_13 PFAM thiamineS protein - - - 0.00055 46.0
PYH2_k127_5675087_2 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K00087,K03519 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000002349 216.0
PYH2_k127_5675087_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000456 177.0
PYH2_k127_5675087_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000465 139.0
PYH2_k127_5675087_5 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000001504 135.0
PYH2_k127_5675087_6 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K18021 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.5.3,1.2.99.8 0.000000000000000000000000000000009484 136.0
PYH2_k127_5675087_7 - - - - 0.000000000000000000000000000086 122.0
PYH2_k127_5675087_8 PFAM regulatory protein TetR K03577,K18939 - - 0.0000000000000000000000008588 111.0
PYH2_k127_5675087_9 Transcriptional regulator K07729 - - 0.000000000000000000008504 94.0
PYH2_k127_5696659_0 DEAD DEAH box helicase domain protein K03724 - - 1.394e-247 796.0
PYH2_k127_5696659_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.487e-211 673.0
PYH2_k127_5696659_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000267 209.0
PYH2_k127_5696659_11 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000001333 198.0
PYH2_k127_5696659_12 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000121 156.0
PYH2_k127_5696659_13 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000005789 174.0
PYH2_k127_5696659_14 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000004775 121.0
PYH2_k127_5696659_15 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000004553 109.0
PYH2_k127_5696659_16 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000009713 101.0
PYH2_k127_5696659_17 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000002152 107.0
PYH2_k127_5696659_18 Belongs to the UPF0218 family K09735 - - 0.000000000000000000001788 104.0
PYH2_k127_5696659_19 binds to the 23S rRNA K02921 - - 0.000000000000000000002119 99.0
PYH2_k127_5696659_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 503.0
PYH2_k127_5696659_20 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000003749 82.0
PYH2_k127_5696659_21 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000403 82.0
PYH2_k127_5696659_22 Fcf1 K07158 - - 0.0000000000000008313 82.0
PYH2_k127_5696659_23 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000005784 74.0
PYH2_k127_5696659_24 KEOPS complex Pcc1-like subunit K09741 - - 0.0004688 46.0
PYH2_k127_5696659_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 492.0
PYH2_k127_5696659_4 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 489.0
PYH2_k127_5696659_5 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 307.0
PYH2_k127_5696659_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 286.0
PYH2_k127_5696659_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002809 252.0
PYH2_k127_5696659_8 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000002932 221.0
PYH2_k127_5696659_9 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000003094 213.0
PYH2_k127_5711264_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 428.0
PYH2_k127_5711264_1 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
PYH2_k127_5711264_2 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000001556 213.0
PYH2_k127_5711264_3 Subtilase family - - - 0.000000000000000004119 99.0
PYH2_k127_5711264_4 Terminase-like family - - - 0.00000001316 64.0
PYH2_k127_5711264_5 PFAM protein phosphatase 2C K01090 - 3.1.3.16 0.000004603 51.0
PYH2_k127_5711264_6 cAMP biosynthetic process K18672 - 2.7.7.85 0.0001173 54.0
PYH2_k127_5722713_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004426 281.0
PYH2_k127_5722713_2 Probable zinc-ribbon domain - - - 0.0002281 47.0
PYH2_k127_5774435_0 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 406.0
PYH2_k127_5774435_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 364.0
PYH2_k127_5774435_2 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 362.0
PYH2_k127_5774435_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 308.0
PYH2_k127_5774435_4 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004351 288.0
PYH2_k127_5774435_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 271.0
PYH2_k127_5774435_6 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000001146 263.0
PYH2_k127_5774435_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000001452 189.0
PYH2_k127_5774435_8 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000009534 65.0
PYH2_k127_5774435_9 lactoylglutathione lyase activity K08234 - - 0.000002591 56.0
PYH2_k127_5875826_0 Nickel-dependent hydrogenase - - - 8.969e-209 657.0
PYH2_k127_5875826_1 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 525.0
PYH2_k127_5875826_10 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000001684 146.0
PYH2_k127_5875826_11 OsmC-like protein - - - 0.0000000000000000000000000000000001087 138.0
PYH2_k127_5875826_12 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000000000000002122 141.0
PYH2_k127_5875826_13 Methyltransferase domain K02493 - 2.1.1.297 0.00000000000000000000000000046 121.0
PYH2_k127_5875826_14 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000006179 123.0
PYH2_k127_5875826_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 493.0
PYH2_k127_5875826_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 388.0
PYH2_k127_5875826_4 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 389.0
PYH2_k127_5875826_5 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 329.0
PYH2_k127_5875826_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
PYH2_k127_5875826_7 radical SAM domain protein K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000005469 238.0
PYH2_k127_5875826_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
PYH2_k127_5875826_9 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
PYH2_k127_5904862_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 504.0
PYH2_k127_5904862_1 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000002462 166.0
PYH2_k127_5904862_2 Belongs to the UPF0273 family - - - 0.0000000000000000000000000000000000001134 152.0
PYH2_k127_5904862_3 Transcriptional regulator, TrmB - - - 0.0000000000000000000000002675 115.0
PYH2_k127_5911235_0 Methyltransferase K07579 - - 0.00000000000000000000000000000000000000001582 160.0
PYH2_k127_5911235_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000001689 122.0
PYH2_k127_5911235_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000005787 106.0
PYH2_k127_5911235_3 Belongs to the UPF0215 family K09120 - - 0.000000000000000008302 91.0
PYH2_k127_5911235_4 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000003255 77.0
PYH2_k127_5911235_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000227 70.0
PYH2_k127_5911235_6 Diphthamide K07561 - 2.5.1.108 0.00000000001106 66.0
PYH2_k127_5911235_7 Ribonuclease III - - - 0.0000001146 59.0
PYH2_k127_5924439_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.446e-237 750.0
PYH2_k127_5924439_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 583.0
PYH2_k127_5924439_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 451.0
PYH2_k127_5924439_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane K08265,K16887 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 392.0
PYH2_k127_5924439_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 366.0
PYH2_k127_5924439_5 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 302.0
PYH2_k127_5924439_6 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000643 286.0
PYH2_k127_5924439_7 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000002009 217.0
PYH2_k127_5924439_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000009248 160.0
PYH2_k127_5924439_9 Thiamine biosynthesis protein ThiJ K18199 - 4.2.1.103 0.000000000000000000000000001345 120.0
PYH2_k127_5929353_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 332.0
PYH2_k127_5929353_1 methylmalonyl-CoA K01849 - 5.4.99.2 0.000000000000000000001022 97.0
PYH2_k127_6030232_0 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 472.0
PYH2_k127_6030232_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 399.0
PYH2_k127_6030232_2 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000001244 55.0
PYH2_k127_6055549_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 366.0
PYH2_k127_6055549_1 major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000003202 131.0
PYH2_k127_6055549_2 - - - - 0.000000000000000000000573 101.0
PYH2_k127_6055549_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000006456 106.0
PYH2_k127_6055549_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002391 71.0
PYH2_k127_6150493_0 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 384.0
PYH2_k127_6150493_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 332.0
PYH2_k127_6150493_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000002518 258.0
PYH2_k127_6150493_3 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000004904 66.0
PYH2_k127_6192788_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.725e-197 630.0
PYH2_k127_6192788_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 361.0
PYH2_k127_6192788_2 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000005194 202.0
PYH2_k127_6192788_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000008388 56.0
PYH2_k127_6300462_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000002866 219.0
PYH2_k127_6300462_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000009659 209.0
PYH2_k127_6300462_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000002234 190.0
PYH2_k127_6300462_3 Tellurite resistance protein TehB - - - 0.00000000000000003237 89.0
PYH2_k127_6300462_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000001253 68.0
PYH2_k127_6317276_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 380.0
PYH2_k127_6317276_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
PYH2_k127_6317276_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
PYH2_k127_6317276_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000006245 213.0
PYH2_k127_6317276_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000004171 179.0
PYH2_k127_6317276_5 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009181 126.0
PYH2_k127_6317276_6 Domain of unknown function (DUF2088) - - - 0.0000000000000000000009148 108.0
PYH2_k127_6317276_7 - - - - 0.0000000008061 72.0
PYH2_k127_6317276_8 Lrp/AsnC ligand binding domain - - - 0.0002307 51.0
PYH2_k127_6545061_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.811e-262 832.0
PYH2_k127_6545061_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 506.0
PYH2_k127_6545061_10 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000007138 89.0
PYH2_k127_6545061_11 metalloendopeptidase activity - - - 0.000001522 55.0
PYH2_k127_6545061_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 470.0
PYH2_k127_6545061_3 GTPase of unknown function C-terminal K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 458.0
PYH2_k127_6545061_4 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 446.0
PYH2_k127_6545061_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 430.0
PYH2_k127_6545061_6 Protein of unknown function (DUF1512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 321.0
PYH2_k127_6545061_7 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000003139 240.0
PYH2_k127_6545061_8 Helix-turn-helix domain - - - 0.00000000000000000000000000000003608 132.0
PYH2_k127_6545061_9 CAAX protease self-immunity - - - 0.00000000000000000000407 106.0
PYH2_k127_6549540_0 PFAM ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 481.0
PYH2_k127_6549540_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 444.0
PYH2_k127_6549540_2 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 365.0
PYH2_k127_6549540_3 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 323.0
PYH2_k127_6549540_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 298.0
PYH2_k127_6549540_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
PYH2_k127_6549540_6 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000002864 213.0
PYH2_k127_6550764_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 340.0
PYH2_k127_6550764_1 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000001506 105.0
PYH2_k127_6550764_2 SCO1/SenC K03619,K07152 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.00000006083 61.0
PYH2_k127_6550764_3 Glycosyl transferase, family 2 - - - 0.0002036 53.0
PYH2_k127_6576671_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 418.0
PYH2_k127_6576671_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 351.0
PYH2_k127_6576671_2 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001098 289.0
PYH2_k127_6576671_3 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000003367 209.0
PYH2_k127_6576671_4 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000002158 159.0
PYH2_k127_6576671_5 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000001323 156.0
PYH2_k127_6576671_6 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000004084 113.0
PYH2_k127_6588628_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
PYH2_k127_6588628_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000004395 203.0
PYH2_k127_6588628_2 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000006365 80.0
PYH2_k127_6588628_3 - - - - 0.000000000002818 69.0
PYH2_k127_6588628_4 - - - - 0.000000313 55.0
PYH2_k127_6588628_5 HNH nucleases - - - 0.00001749 48.0
PYH2_k127_6628088_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 602.0
PYH2_k127_6628088_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000002384 148.0
PYH2_k127_6628088_2 - K00960 - 2.7.7.6 0.00000000000000302 76.0
PYH2_k127_6628088_3 Sec61beta family - - - 0.00000001092 58.0
PYH2_k127_6628088_4 ZPR1-related zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000002613 56.0
PYH2_k127_6656008_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 454.0
PYH2_k127_6656008_1 Glycolate oxidase subunit (GlcD) K00104,K21836 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0036094,GO:0043167,GO:0043168,GO:0047809,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.3.15,1.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 417.0
PYH2_k127_6656008_10 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000001277 185.0
PYH2_k127_6656008_11 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000001094 177.0
PYH2_k127_6656008_12 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000006598 168.0
PYH2_k127_6656008_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000006442 150.0
PYH2_k127_6656008_14 GDP-mannose mannosyl hydrolase activity K03207,K12944 - - 0.00000000000000000000000000000000006252 138.0
PYH2_k127_6656008_15 PFAM amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000005235 143.0
PYH2_k127_6656008_16 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000003342 127.0
PYH2_k127_6656008_17 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002069 117.0
PYH2_k127_6656008_18 PAC2 family K07159 - - 0.00000000000000000003636 100.0
PYH2_k127_6656008_19 nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module K07060 - - 0.0000000000000000006123 94.0
PYH2_k127_6656008_2 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 369.0
PYH2_k127_6656008_20 - - - - 0.00000000001858 68.0
PYH2_k127_6656008_21 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000007948 67.0
PYH2_k127_6656008_22 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000003294 55.0
PYH2_k127_6656008_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00004824 51.0
PYH2_k127_6656008_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 313.0
PYH2_k127_6656008_4 FtsJ-like methyltransferase K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001269 287.0
PYH2_k127_6656008_5 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
PYH2_k127_6656008_6 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000008719 218.0
PYH2_k127_6656008_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000006289 210.0
PYH2_k127_6656008_8 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000001961 194.0
PYH2_k127_6656008_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000005527 196.0
PYH2_k127_6657571_0 Heat shock 70 kDa protein K04043 - - 2.488e-232 734.0
PYH2_k127_6657571_1 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 479.0
PYH2_k127_6657571_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 385.0
PYH2_k127_6657571_3 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001089 286.0
PYH2_k127_6657571_4 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000365 182.0
PYH2_k127_6657571_5 Thiamine transporter YuaJ K16789 - - 0.0000000000000000000000000000000000000000001431 166.0
PYH2_k127_6657571_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000003297 123.0
PYH2_k127_6668528_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1049.0
PYH2_k127_6668528_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000002089 184.0
PYH2_k127_6668528_2 Peptidase C13 family - - - 0.0000000005978 71.0
PYH2_k127_6672101_0 ERCC4 domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 615.0
PYH2_k127_6672101_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 265.0
PYH2_k127_6672101_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000005152 234.0
PYH2_k127_6672101_3 phosphoesterase RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000004443 184.0
PYH2_k127_6672101_4 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000002542 159.0
PYH2_k127_6672101_5 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000000005015 76.0
PYH2_k127_6672101_6 Iron-sulfur cluster-binding domain - - - 0.0007936 44.0
PYH2_k127_6682937_0 aspartate racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 310.0
PYH2_k127_6682937_1 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 293.0
PYH2_k127_6682937_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000002186 241.0
PYH2_k127_6682937_3 F420H(2)-dependent quinone reductase - - - 0.00000000000000003124 87.0
PYH2_k127_6682937_5 ABC-type transport system, involved in lipoprotein release, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00001158 48.0
PYH2_k127_6682937_6 Belongs to the peptidase S8 family K14645 - - 0.0004119 48.0
PYH2_k127_6684001_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008764 268.0
PYH2_k127_6684001_1 Cytochrome b(N-terminal)/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000002163 195.0
PYH2_k127_6684001_2 - - - - 0.0000000000000000000000000000000000000001844 162.0
PYH2_k127_6684001_3 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000006554 121.0
PYH2_k127_6684001_4 Rieske [2Fe-2S] domain K08355 - 1.20.2.1,1.20.9.1 0.00000000000000000000000003856 114.0
PYH2_k127_6684001_5 Cytochrome b subunit of the bc complex K00412,K15879 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000002481 111.0
PYH2_k127_6684001_6 - - - - 0.00000000000000001225 87.0
PYH2_k127_6688719_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 370.0
PYH2_k127_6688719_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 323.0
PYH2_k127_6688719_2 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000001602 193.0
PYH2_k127_6688719_3 deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000417 181.0
PYH2_k127_6727964_0 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 392.0
PYH2_k127_6727964_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 357.0
PYH2_k127_6727964_10 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000001937 196.0
PYH2_k127_6727964_11 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000004046 175.0
PYH2_k127_6727964_12 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000003975 164.0
PYH2_k127_6727964_13 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000005436 151.0
PYH2_k127_6727964_14 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000003521 138.0
PYH2_k127_6727964_15 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000008971 132.0
PYH2_k127_6727964_16 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000001449 131.0
PYH2_k127_6727964_18 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000002247 125.0
PYH2_k127_6727964_19 Tricorn protease homolog K08676 - - 0.000000000000003221 81.0
PYH2_k127_6727964_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 342.0
PYH2_k127_6727964_20 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768,K07151 - 2.4.99.18,5.2.1.8 0.000000000002298 81.0
PYH2_k127_6727964_21 - - - - 0.000000009094 61.0
PYH2_k127_6727964_22 - - - - 0.000000188 58.0
PYH2_k127_6727964_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 306.0
PYH2_k127_6727964_4 Spermidine putrescine-binding periplasmic protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000015 267.0
PYH2_k127_6727964_5 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007018 250.0
PYH2_k127_6727964_6 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 237.0
PYH2_k127_6727964_7 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000001176 229.0
PYH2_k127_6727964_8 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000004559 217.0
PYH2_k127_6727964_9 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000002793 195.0
PYH2_k127_6774858_0 DEAD DEAH box helicase domain protein K03724 - - 4.754e-201 660.0
PYH2_k127_6774858_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 373.0
PYH2_k127_6774858_10 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000001742 138.0
PYH2_k127_6774858_11 AAA domain K12614 GO:0000724,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0030915,GO:0032991,GO:0033554,GO:0033676,GO:0034641,GO:0035861,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050000,GO:0050896,GO:0051179,GO:0051304,GO:0051640,GO:0051641,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0090734,GO:0097159,GO:0097240,GO:0106068,GO:1901360,GO:1901363,GO:1902494,GO:1990234,GO:1990683 3.6.4.13 0.000000000000000001017 101.0
PYH2_k127_6774858_12 to Saccharomyces cerevisiae SMC5 (YOL034W) - GO:0000166,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022402,GO:0030554,GO:0030915,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051304,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0106068,GO:1901265,GO:1901360,GO:1901363,GO:1902494,GO:1990234 - 0.0000000000000006105 92.0
PYH2_k127_6774858_13 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.0000000000000103 79.0
PYH2_k127_6774858_14 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000696 55.0
PYH2_k127_6774858_15 H ACA RNA-protein complex K07569 - - 0.000001689 53.0
PYH2_k127_6774858_16 COG1361 S-layer domain - - - 0.000007386 57.0
PYH2_k127_6774858_2 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 377.0
PYH2_k127_6774858_3 ABC-type cobalt transport system ATPase component K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003169 281.0
PYH2_k127_6774858_4 ATP-binding protein K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001342 255.0
PYH2_k127_6774858_5 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000001629 232.0
PYH2_k127_6774858_6 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000389 218.0
PYH2_k127_6774858_7 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000008932 189.0
PYH2_k127_6774858_8 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000004001 188.0
PYH2_k127_6774858_9 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000001803 151.0
PYH2_k127_678949_0 in RNase L inhibitor, RLI K06174 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 617.0
PYH2_k127_678949_1 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 550.0
PYH2_k127_678949_10 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000001272 129.0
PYH2_k127_678949_11 signal transduction protein with CBS domains - - - 0.000000000000000000000000000009395 123.0
PYH2_k127_678949_12 TraB family - - - 0.00000000000000000000000001192 119.0
PYH2_k127_678949_13 - - - - 0.00000000000000000000006807 105.0
PYH2_k127_678949_14 - - - - 0.00000000000003301 74.0
PYH2_k127_678949_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000002749 73.0
PYH2_k127_678949_16 - - - - 0.00000005622 57.0
PYH2_k127_678949_17 Domain of unknown function (DUF4443) - - - 0.000001075 57.0
PYH2_k127_678949_18 archaeal coiled-coil protein - - - 0.000198 53.0
PYH2_k127_678949_19 chromosome segregation and condensation protein ScpA K05896 - - 0.0007687 49.0
PYH2_k127_678949_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 473.0
PYH2_k127_678949_3 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 306.0
PYH2_k127_678949_4 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002356 242.0
PYH2_k127_678949_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000257 244.0
PYH2_k127_678949_6 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000007729 227.0
PYH2_k127_678949_7 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000001625 212.0
PYH2_k127_678949_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000007046 149.0
PYH2_k127_678949_9 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000002242 131.0
PYH2_k127_6794346_0 aldo keto reductase K18471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 419.0
PYH2_k127_6794346_1 Transketolase, central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 384.0
PYH2_k127_6794346_10 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000000000000000000000000000000000006603 142.0
PYH2_k127_6794346_11 Haem-degrading - - - 0.0000000000000000000000000000000001682 136.0
PYH2_k127_6794346_12 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000001051 139.0
PYH2_k127_6794346_13 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000003249 113.0
PYH2_k127_6794346_14 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.0000000000001226 79.0
PYH2_k127_6794346_15 PFAM Cobalt transport protein K16785 - - 0.000000000103 72.0
PYH2_k127_6794346_2 ATPase component of various ABC-type transport systems with duplicated ATPase domain K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 383.0
PYH2_k127_6794346_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 310.0
PYH2_k127_6794346_4 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 301.0
PYH2_k127_6794346_5 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008682 293.0
PYH2_k127_6794346_6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005289 286.0
PYH2_k127_6794346_7 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000002561 253.0
PYH2_k127_6794346_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000133 199.0
PYH2_k127_6794346_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000006601 184.0
PYH2_k127_6804158_0 Protein of unknown function (DUF4013) - - - 0.0000000000000000000000000000000000000000001513 169.0
PYH2_k127_6804158_1 membrane protein domain - - - 0.000000000000000000001944 101.0
PYH2_k127_6804158_2 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000132 70.0
PYH2_k127_6827246_0 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000001405 174.0
PYH2_k127_6827246_1 lyase activity - - - 0.0000000000000000000000000000000000000000001322 166.0
PYH2_k127_6827246_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.000000000000000000000000000000000000000004485 158.0
PYH2_k127_6827246_3 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000004026 126.0
PYH2_k127_6827246_4 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000000702 99.0
PYH2_k127_6827246_5 Aminopeptidase Iap family-like protein - - - 0.00000000000716 72.0
PYH2_k127_6838389_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 471.0
PYH2_k127_6838389_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 363.0
PYH2_k127_6838389_2 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000003025 172.0
PYH2_k127_6838389_3 - - - - 0.00000005589 60.0
PYH2_k127_6877687_0 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 482.0
PYH2_k127_6877687_1 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 380.0
PYH2_k127_6877687_2 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 343.0
PYH2_k127_6877687_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
PYH2_k127_6877687_4 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000004513 162.0
PYH2_k127_6877687_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.000000000000000000000001262 105.0
PYH2_k127_6877687_7 Fibronectin type III domain K03933 - - 0.00000000000584 76.0
PYH2_k127_6979417_0 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 413.0
PYH2_k127_6979417_1 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000005286 217.0
PYH2_k127_6979417_2 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.000000000000000000000000000000008024 134.0
PYH2_k127_7004085_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 340.0
PYH2_k127_7004085_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 318.0
PYH2_k127_7004085_10 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000131 83.0
PYH2_k127_7004085_12 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000002759 59.0
PYH2_k127_7004085_13 Bacterial extracellular solute-binding protein - - - 0.0000001906 63.0
PYH2_k127_7004085_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052,K11072 - 3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 298.0
PYH2_k127_7004085_3 COG4608 ABC-type oligopeptide transport system, ATPase component K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 296.0
PYH2_k127_7004085_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000119 263.0
PYH2_k127_7004085_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000003889 246.0
PYH2_k127_7004085_6 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000005564 150.0
PYH2_k127_7004085_7 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000001011 112.0
PYH2_k127_7004085_8 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000009795 102.0
PYH2_k127_7004085_9 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000002422 94.0
PYH2_k127_7046861_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 303.0
PYH2_k127_7046861_1 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
PYH2_k127_7046861_10 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000006696 52.0
PYH2_k127_7046861_2 - - - - 0.00000000000000000000000000000000000000000000000000000002586 204.0
PYH2_k127_7046861_3 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000001447 170.0
PYH2_k127_7046861_4 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.00000000000000000000000000000000000000007329 154.0
PYH2_k127_7046861_5 ECF-type riboflavin transporter, S component - - - 0.0000000000000000000000000000000000004332 145.0
PYH2_k127_7046861_6 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000002714 134.0
PYH2_k127_7046861_7 HIT domain K02503 - - 0.0000000000000000000000001152 111.0
PYH2_k127_7046861_8 - - - - 0.00000000000000000000003646 106.0
PYH2_k127_7046861_9 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.0000000000000007366 79.0
PYH2_k127_7052008_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1022.0
PYH2_k127_7052008_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 487.0
PYH2_k127_7052008_2 Belongs to the phosphohexose mutase family K22199 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000002744 254.0
PYH2_k127_7107272_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001351 226.0
PYH2_k127_7107272_1 - - - - 0.000000000000000000000004343 111.0
PYH2_k127_7107272_2 PFAM cyclic nucleotide-binding K16922 - - 0.000000000000000000000007911 115.0
PYH2_k127_7107272_3 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000000000000002689 94.0
PYH2_k127_7251075_0 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001195 149.0
PYH2_k127_7251075_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000008466 142.0
PYH2_k127_7251075_2 PFAM Molybdopterin guanine dinucleotide synthesis protein B K06947 - - 0.00000000000000000000000000000000002701 149.0
PYH2_k127_7251075_3 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000002919 105.0
PYH2_k127_7284132_0 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 306.0
PYH2_k127_7284132_1 - - - - 0.000000000000000000000000000000000000000000000007064 183.0
PYH2_k127_7284132_2 Putative serine dehydratase domain - - - 0.0000000000000003113 83.0
PYH2_k127_73968_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.133e-233 735.0
PYH2_k127_73968_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 588.0
PYH2_k127_73968_10 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 304.0
PYH2_k127_73968_11 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000002682 262.0
PYH2_k127_73968_12 Chorismate mutase type II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000281 258.0
PYH2_k127_73968_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000008126 182.0
PYH2_k127_73968_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000001209 177.0
PYH2_k127_73968_15 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000002222 153.0
PYH2_k127_73968_16 Methyltransferase domain K06987 - - 0.00000000000000000000000000000007955 133.0
PYH2_k127_73968_17 prephenate dehydrogenase K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.0000000000000000000000000004422 124.0
PYH2_k127_73968_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 574.0
PYH2_k127_73968_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 494.0
PYH2_k127_73968_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 454.0
PYH2_k127_73968_5 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 367.0
PYH2_k127_73968_6 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 331.0
PYH2_k127_73968_7 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 332.0
PYH2_k127_73968_8 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
PYH2_k127_73968_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 310.0
PYH2_k127_7483414_0 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 392.0
PYH2_k127_7483414_1 PFAM NmrA family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002162 285.0
PYH2_k127_7483414_10 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000006062 153.0
PYH2_k127_7483414_11 extracellular matrix structural constituent - - - 0.00000000000000000000004693 113.0
PYH2_k127_7483414_12 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000005024 99.0
PYH2_k127_7483414_13 PFAM ABC-2 type transporter K01992 - - 0.0000000000000001418 92.0
PYH2_k127_7483414_14 Major facilitator superfamily - - - 0.000000001633 70.0
PYH2_k127_7483414_15 ABC-2 family transporter protein K01992 - - 0.00000004616 65.0
PYH2_k127_7483414_16 dipeptidase activity - - - 0.0003314 43.0
PYH2_k127_7483414_2 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 271.0
PYH2_k127_7483414_3 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002386 255.0
PYH2_k127_7483414_4 spore germination K07790 - - 0.00000000000000000000000000000000000000000000000001634 192.0
PYH2_k127_7483414_5 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000003521 188.0
PYH2_k127_7483414_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000001878 174.0
PYH2_k127_7483414_7 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000008701 173.0
PYH2_k127_7483414_8 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000006147 170.0
PYH2_k127_7483414_9 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.000000000000000000000000000000000000000000981 167.0
PYH2_k127_7489699_0 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 372.0
PYH2_k127_7489699_1 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000775 210.0
PYH2_k127_7489699_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000002904 184.0
PYH2_k127_7563350_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 2.033e-218 691.0
PYH2_k127_7563350_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 4.44e-214 685.0
PYH2_k127_7563350_10 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 396.0
PYH2_k127_7563350_11 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 389.0
PYH2_k127_7563350_12 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 383.0
PYH2_k127_7563350_13 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 381.0
PYH2_k127_7563350_14 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 383.0
PYH2_k127_7563350_15 oligopeptide dipeptide ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 373.0
PYH2_k127_7563350_16 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 364.0
PYH2_k127_7563350_17 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 356.0
PYH2_k127_7563350_18 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
PYH2_k127_7563350_19 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
PYH2_k127_7563350_2 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 5.303e-209 663.0
PYH2_k127_7563350_20 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 326.0
PYH2_k127_7563350_21 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009794 278.0
PYH2_k127_7563350_22 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001535 270.0
PYH2_k127_7563350_23 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001338 263.0
PYH2_k127_7563350_24 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000001191 246.0
PYH2_k127_7563350_25 Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000000000000000001014 223.0
PYH2_k127_7563350_26 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000001456 226.0
PYH2_k127_7563350_27 - - - - 0.00000000000000000000000000000000000000000000000002249 188.0
PYH2_k127_7563350_28 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000000000000000000000000000000000000004492 183.0
PYH2_k127_7563350_29 PFAM ParB domain protein nuclease - - - 0.0000000000000000000000000000000000000001413 163.0
PYH2_k127_7563350_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 565.0
PYH2_k127_7563350_30 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000004169 136.0
PYH2_k127_7563350_31 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000000000000000001118 124.0
PYH2_k127_7563350_32 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000001013 117.0
PYH2_k127_7563350_33 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000000006644 112.0
PYH2_k127_7563350_34 PFAM PAC2 family K06869 - - 0.0000000000000000000000002026 115.0
PYH2_k127_7563350_35 PFAM Transcription factor CBF NF-Y histone domain protein - - - 0.00000000000001273 76.0
PYH2_k127_7563350_36 PFAM Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000711 75.0
PYH2_k127_7563350_37 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000002421 76.0
PYH2_k127_7563350_38 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000003312 75.0
PYH2_k127_7563350_39 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000005499 77.0
PYH2_k127_7563350_4 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 495.0
PYH2_k127_7563350_40 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.00000000001071 69.0
PYH2_k127_7563350_41 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.00000000002421 65.0
PYH2_k127_7563350_42 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000002144 72.0
PYH2_k127_7563350_43 TIGRFAM MoaD family protein K03636 - - 0.00000001162 60.0
PYH2_k127_7563350_44 Thioredoxin K03671 - - 0.00000033 57.0
PYH2_k127_7563350_45 - - - - 0.000003296 50.0
PYH2_k127_7563350_46 - - - - 0.0000168 55.0
PYH2_k127_7563350_5 Penicillin amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 492.0
PYH2_k127_7563350_6 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 456.0
PYH2_k127_7563350_7 actin actin family protein K18641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 442.0
PYH2_k127_7563350_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 404.0
PYH2_k127_7563350_9 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K10824,K12372,K13892 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 396.0
PYH2_k127_7566777_0 Ribosome biogenesis protein, C-terminal K09140 - - 0.00000000000000000000000000000000000006442 150.0
PYH2_k127_7566777_1 - - - - 0.0000000000003223 70.0
PYH2_k127_7566777_2 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.000000000008246 75.0
PYH2_k127_7568575_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 538.0
PYH2_k127_7568575_1 E3 Ubiquitin ligase - - - 0.0000000000000006023 91.0
PYH2_k127_7568575_2 LemA family K03744 - - 0.0000000000000775 76.0
PYH2_k127_7583877_0 PFAM Prolyl oligopeptidase family - - - 1.05e-263 826.0
PYH2_k127_7583877_1 AAA-like domain - - - 9.01e-255 810.0
PYH2_k127_7583877_10 ectoine utilization protein EutD - - - 0.0000000000000000000000000000000000000000000000000000000000002966 228.0
PYH2_k127_7583877_11 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000000000000003805 205.0
PYH2_k127_7583877_12 PFAM Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000003061 191.0
PYH2_k127_7583877_13 membrane - - - 0.00000000000000000000000000000000000000000000000002358 185.0
PYH2_k127_7583877_14 oxidase, subunit K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000005862 182.0
PYH2_k127_7583877_15 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000003021 176.0
PYH2_k127_7583877_16 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000005158 165.0
PYH2_k127_7583877_17 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000002636 156.0
PYH2_k127_7583877_18 VIT family - - - 0.00000000000000000000000000000003058 136.0
PYH2_k127_7583877_19 Trypsin-like serine protease - - - 0.0000000000000000000000000002526 126.0
PYH2_k127_7583877_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.098e-241 775.0
PYH2_k127_7583877_20 Peptidyl-prolyl cis-trans isomerase K01802,K03769 - 5.2.1.8 0.00000000000000000000000001732 111.0
PYH2_k127_7583877_21 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000008901 108.0
PYH2_k127_7583877_22 Cytochrome bd-type quinol oxidase, subunit K00425 - 1.10.3.14 0.000000000000000000001046 108.0
PYH2_k127_7583877_23 Rubredoxin - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000059 91.0
PYH2_k127_7583877_24 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000001111 96.0
PYH2_k127_7583877_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000006158 86.0
PYH2_k127_7583877_26 Domain of unknown function (DUF1508) K09946 - - 0.000000000000135 72.0
PYH2_k127_7583877_27 DinB family - - - 0.00000000004086 69.0
PYH2_k127_7583877_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0002151 49.0
PYH2_k127_7583877_3 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 421.0
PYH2_k127_7583877_4 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 347.0
PYH2_k127_7583877_5 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 332.0
PYH2_k127_7583877_6 TIGRFAM MIP family channel K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 318.0
PYH2_k127_7583877_7 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 313.0
PYH2_k127_7583877_8 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000003166 242.0
PYH2_k127_7583877_9 of the drug metabolite transporter (DMT) superfamily - GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000005262 225.0
PYH2_k127_7623758_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 2.002e-223 730.0
PYH2_k127_7623758_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 601.0
PYH2_k127_7623758_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 419.0
PYH2_k127_7623758_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 379.0
PYH2_k127_7623758_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 317.0
PYH2_k127_7623758_5 GINS complex protein K09723 - - 0.00000000000003012 79.0
PYH2_k127_7633864_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 566.0
PYH2_k127_7633864_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 520.0
PYH2_k127_7633864_10 ATP-binding domain-containing protein - - - 0.000000003527 61.0
PYH2_k127_7633864_11 Domain of unknown function (DUF4129) - - - 0.0002199 52.0
PYH2_k127_7633864_2 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 385.0
PYH2_k127_7633864_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001694 154.0
PYH2_k127_7633864_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000002037 159.0
PYH2_k127_7633864_5 Belongs to the MCM family K02212 GO:0000003,GO:0000228,GO:0000278,GO:0000724,GO:0000725,GO:0000727,GO:0000785,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003688,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005656,GO:0005657,GO:0005694,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006267,GO:0006268,GO:0006270,GO:0006271,GO:0006275,GO:0006279,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022607,GO:0022616,GO:0030874,GO:0030875,GO:0031261,GO:0031298,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032780,GO:0032991,GO:0032993,GO:0033043,GO:0033044,GO:0033260,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0036387,GO:0036388,GO:0042555,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043462,GO:0043565,GO:0043596,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044454,GO:0044464,GO:0044786,GO:0045005,GO:0045934,GO:0046483,GO:0048478,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051095,GO:0051097,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051321,GO:0051336,GO:0051346,GO:0051716,GO:0060255,GO:0065003,GO:0065004,GO:0065007,GO:0065009,GO:0070013,GO:0071103,GO:0071162,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097373,GO:1901360,GO:1901363,GO:1901576,GO:1902292,GO:1902299,GO:1902315,GO:1902449,GO:1902450,GO:1902969,GO:1902975,GO:1903046,GO:1903047,GO:1905462,GO:1905463,GO:1905774,GO:1905775,GO:1990837,GO:2000104,GO:2000112,GO:2000113,GO:2001251 3.6.4.12 0.000000000000000000001159 107.0
PYH2_k127_7633864_6 phosphatase activity K05967 - - 0.0000000000000003548 86.0
PYH2_k127_7633864_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000002084 86.0
PYH2_k127_7633864_8 serine threonine protein kinase K08884 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000001099 82.0
PYH2_k127_7633864_9 Psort location CytoplasmicMembrane, score K16927 - - 0.00000000005983 72.0
PYH2_k127_7658023_0 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 442.0
PYH2_k127_7658023_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 377.0
PYH2_k127_7658023_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 338.0
PYH2_k127_7658023_3 Belongs to the UPF0292 family - - - 0.000000000000004097 80.0
PYH2_k127_7658023_4 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000001016 66.0
PYH2_k127_7685693_0 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000000000000000000000000001218 186.0
PYH2_k127_7685693_1 - - - - 0.00000000000000000000000000000000000000000505 168.0
PYH2_k127_7685693_2 - - - - 0.00000000000000000000000000000000000000002797 156.0
PYH2_k127_7685693_3 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000001414 129.0
PYH2_k127_7685693_4 phosphatidylinositol metabolic process - - - 0.00000000000000000000000000408 125.0
PYH2_k127_7685693_5 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000003558 108.0
PYH2_k127_7685693_6 Peptidase C13 family - - - 0.000000000007428 79.0
PYH2_k127_7685693_7 Parallel beta-helix repeats - - - 0.0000001155 66.0
PYH2_k127_7685693_8 - - - - 0.00002879 53.0
PYH2_k127_7769410_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 456.0
PYH2_k127_7769410_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
PYH2_k127_7769410_10 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000006112 116.0
PYH2_k127_7769410_11 Protein of unknown function (DUF424) K09148 - - 0.0000000000000001246 83.0
PYH2_k127_7769410_12 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.0001491 49.0
PYH2_k127_7769410_2 Serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000006295 220.0
PYH2_k127_7769410_3 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000003323 186.0
PYH2_k127_7769410_4 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000001441 179.0
PYH2_k127_7769410_5 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000001092 176.0
PYH2_k127_7769410_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000001506 141.0
PYH2_k127_7769410_7 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000001147 121.0
PYH2_k127_7769410_8 Flavin reductase-like protein - - - 0.0000000000000000000000000000849 122.0
PYH2_k127_7769410_9 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000001185 130.0
PYH2_k127_7898383_0 formate C-acetyltransferase glycine radical - - - 5.233e-224 719.0
PYH2_k127_7898383_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
PYH2_k127_7898383_2 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009399 267.0
PYH2_k127_7898383_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000002872 145.0
PYH2_k127_7898383_4 protein secretion by the type IV secretion system - - - 0.0000000000000000000000000000000008671 151.0
PYH2_k127_7898383_5 RNA-binding protein contains TRAM domain - - - 0.000000000000000003419 85.0
PYH2_k127_7898383_6 antibiotic catabolic process K13277,K20276 - - 0.000005813 60.0
PYH2_k127_7898383_7 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.0006003 48.0
PYH2_k127_7931582_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 294.0
PYH2_k127_7931582_1 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.0000000000000000000000000000000000000000000000000000000000000000001549 243.0
PYH2_k127_7931582_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K01090 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000004335 224.0
PYH2_k127_7931582_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000001928 94.0
PYH2_k127_7931582_4 SAM-dependent methyltransferase - - - 0.000000000004582 76.0
PYH2_k127_801706_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 387.0
PYH2_k127_801706_1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 329.0
PYH2_k127_801706_2 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002427 214.0
PYH2_k127_801706_3 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000001158 99.0
PYH2_k127_801706_4 Peptidase M1 membrane alanine aminopeptidase - - - 0.0000000000000000000008029 108.0
PYH2_k127_801706_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000004116 97.0
PYH2_k127_8051173_0 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000001881 138.0
PYH2_k127_8051173_1 - - - - 0.0000009142 56.0
PYH2_k127_8091005_0 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 409.0
PYH2_k127_8091005_1 ERCC4 domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000007668 230.0
PYH2_k127_8096195_0 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 442.0
PYH2_k127_8096195_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000003634 181.0
PYH2_k127_8096195_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000007529 169.0
PYH2_k127_8096195_3 EamA-like transporter family - - - 0.000000000000000000000003565 113.0
PYH2_k127_8096195_4 COG1522 Transcriptional regulators - - - 0.00000000000000001369 85.0
PYH2_k127_8123806_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 402.0
PYH2_k127_8123806_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 374.0
PYH2_k127_8123806_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 349.0
PYH2_k127_8123806_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 323.0
PYH2_k127_8123806_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000001836 153.0
PYH2_k127_81529_0 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000009513 238.0
PYH2_k127_81529_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000001874 217.0
PYH2_k127_81529_2 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000006298 130.0
PYH2_k127_81529_3 Parallel beta-helix repeats - - - 0.0000000000000000000000003466 121.0
PYH2_k127_81529_4 Belongs to the ubiquitin-conjugating enzyme family K04649 GO:0000209,GO:0000502,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0016043,GO:0016050,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0030433,GO:0031625,GO:0032446,GO:0032991,GO:0033554,GO:0034976,GO:0036211,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0051716,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070647,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1902494,GO:1905368,GO:1905369 2.3.2.23 0.000000009939 64.0
PYH2_k127_81529_5 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.000001895 61.0
PYH2_k127_81529_6 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00003749 48.0
PYH2_k127_81529_7 - - - - 0.0002456 48.0
PYH2_k127_8165181_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.513e-240 757.0
PYH2_k127_8165181_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 450.0
PYH2_k127_8165181_2 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001308 277.0
PYH2_k127_8165181_3 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000002826 124.0
PYH2_k127_8165181_4 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000166 108.0
PYH2_k127_8165181_5 HD domain K07023 - - 0.00000000000008147 82.0
PYH2_k127_8165181_6 Maintenance of mitochondrial structure and function K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000001097 64.0
PYH2_k127_8187490_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 8.236e-195 626.0
PYH2_k127_8187490_1 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 497.0
PYH2_k127_8187490_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 413.0
PYH2_k127_8187490_3 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 415.0
PYH2_k127_8187490_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
PYH2_k127_8187490_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000001809 237.0
PYH2_k127_8187490_6 Major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000000000000003378 159.0
PYH2_k127_8187490_7 snRNP Sm proteins K04796 - - 0.000000000003366 69.0
PYH2_k127_8187490_8 - - - - 0.000000001336 62.0
PYH2_k127_8187490_9 Helix-turn-helix domain - - - 0.000009544 57.0
PYH2_k127_8299168_0 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
PYH2_k127_8299168_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000002135 83.0
PYH2_k127_8316637_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 383.0
PYH2_k127_8316637_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002057 292.0
PYH2_k127_8316637_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002451 283.0
PYH2_k127_8316637_3 TIGRFAM Shikimate kinase K00891 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.71 0.000000000000000000000000000000000000000000000000000000001095 211.0
PYH2_k127_8316637_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000009178 84.0
PYH2_k127_8370194_0 Acetamidase formamidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
PYH2_k127_8370194_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001733 232.0
PYH2_k127_8370194_2 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH2_k127_8370194_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000003249 179.0
PYH2_k127_8370194_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000004662 164.0
PYH2_k127_8370194_5 amino acid - - - 0.000000000000000149 87.0
PYH2_k127_8410784_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001051 258.0
PYH2_k127_8410784_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
PYH2_k127_8410784_2 Branched-chain amino acid transport system / permease component K02057 - - 0.0007936 44.0
PYH2_k127_8486236_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003791 260.0
PYH2_k127_8486236_1 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000002224 145.0
PYH2_k127_8486236_2 Transcriptional regulator - - - 0.00000000000000000000000003754 117.0
PYH2_k127_8486236_3 Major Facilitator Superfamily - - - 0.000001804 60.0
PYH2_k127_8499196_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 589.0
PYH2_k127_8499196_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 496.0
PYH2_k127_8499196_10 Putative zinc- or iron-chelating domain - - - 0.0000000006438 64.0
PYH2_k127_8499196_11 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.00000000255 61.0
PYH2_k127_8499196_12 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22 0.000001794 59.0
PYH2_k127_8499196_13 - - - - 0.00004611 49.0
PYH2_k127_8499196_14 - - - - 0.0004618 50.0
PYH2_k127_8499196_2 SMART zinc finger, RanBP2-type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 377.0
PYH2_k127_8499196_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 333.0
PYH2_k127_8499196_4 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000006747 204.0
PYH2_k127_8499196_5 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000001056 169.0
PYH2_k127_8499196_6 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000005474 126.0
PYH2_k127_8499196_8 - - - - 0.000000000000006455 79.0
PYH2_k127_8499196_9 Domain of unknown function (DUF4342) - - - 0.00000000000005626 76.0
PYH2_k127_8625835_0 glycosyl transferase family K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000000001148 201.0
PYH2_k127_8625835_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000004401 112.0
PYH2_k127_8639486_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 442.0
PYH2_k127_8639486_1 Molybdopterin dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000003021 130.0
PYH2_k127_8643785_0 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000001328 78.0
PYH2_k127_8821428_0 PFAM DNA polymerase, beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000002077 178.0
PYH2_k127_8821428_1 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.000000000000000000000000000002328 132.0
PYH2_k127_8821428_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000007695 109.0
PYH2_k127_8821428_3 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.000000000000000368 87.0
PYH2_k127_8821428_4 - - - - 0.00001942 55.0
PYH2_k127_8898412_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 587.0
PYH2_k127_8898412_1 Domain of unknown function (DUF5050) - - - 0.0005068 49.0
PYH2_k127_8939744_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 328.0
PYH2_k127_8939744_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008941 287.0
PYH2_k127_8939744_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
PYH2_k127_8939744_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000131 187.0
PYH2_k127_8939744_4 amino acid K03294 - - 0.0000000000000000000000000000000000000000001162 178.0
PYH2_k127_8939744_5 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000007883 152.0
PYH2_k127_8939744_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000006193 99.0
PYH2_k127_8984637_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 493.0
PYH2_k127_8984637_1 Protein of unknown function (DUF1116) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 482.0
PYH2_k127_8984637_10 Membrane - - - 0.0000000000000855 74.0
PYH2_k127_8984637_11 thiolester hydrolase activity K00627,K06889 - 2.3.1.12 0.0000000000002277 73.0
PYH2_k127_8984637_12 Protein of unknown function (DUF2877) - - - 0.00000007528 64.0
PYH2_k127_8984637_2 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 376.0
PYH2_k127_8984637_3 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002281 260.0
PYH2_k127_8984637_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000008283 241.0
PYH2_k127_8984637_5 - - - - 0.0000000000000000000000000000000000000000000000000000003604 201.0
PYH2_k127_8984637_6 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000007037 167.0
PYH2_k127_8984637_7 2Fe-2S -binding domain K03518,K18022 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114 1.2.5.3,1.2.99.8 0.0000000000000000000000003624 106.0
PYH2_k127_8984637_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000002218 90.0
PYH2_k127_8984637_9 Domain of unknown function (DUF1893) - - - 0.00000000000002355 78.0
PYH2_k127_9003388_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1306.0
PYH2_k127_9003388_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03006 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016591,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 9.444e-273 882.0
PYH2_k127_9003388_10 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000003172 198.0
PYH2_k127_9003388_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000003025 196.0
PYH2_k127_9003388_12 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000005027 147.0
PYH2_k127_9003388_13 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000002622 136.0
PYH2_k127_9003388_14 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000002189 133.0
PYH2_k127_9003388_15 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K00332 - 1.6.5.3 0.00000000000000000000000000000009247 131.0
PYH2_k127_9003388_16 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000001799 112.0
PYH2_k127_9003388_17 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000000000003781 108.0
PYH2_k127_9003388_18 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000001378 106.0
PYH2_k127_9003388_19 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000007737 96.0
PYH2_k127_9003388_2 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 529.0
PYH2_k127_9003388_20 DUF72 domain containing protein - - - 0.00000000000000002848 90.0
PYH2_k127_9003388_21 Thiamine-phosphate synthase K22206 - - 0.000000006541 62.0
PYH2_k127_9003388_23 Stage II sporulation protein M - - - 0.000467 52.0
PYH2_k127_9003388_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 509.0
PYH2_k127_9003388_4 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 473.0
PYH2_k127_9003388_5 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 360.0
PYH2_k127_9003388_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 313.0
PYH2_k127_9003388_7 PFAM inner-membrane translocator K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 299.0
PYH2_k127_9003388_8 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000008198 236.0
PYH2_k127_9003388_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
PYH2_k127_9091718_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 503.0
PYH2_k127_9091718_1 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
PYH2_k127_9091718_2 ribosomal protein K02976 - - 0.000000000000000000000000001307 114.0
PYH2_k127_9091718_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000004461 105.0
PYH2_k127_9163560_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.036e-239 767.0
PYH2_k127_9163560_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 395.0
PYH2_k127_9163560_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 373.0
PYH2_k127_9163560_3 Carboxyl transferase domain K19312 GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885 2.1.3.15,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 366.0
PYH2_k127_9163560_4 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000283 241.0
PYH2_k127_9163560_5 PFAM BioY family K03523 - - 0.00000000000000000000000000000000000000000002621 168.0
PYH2_k127_9163560_6 carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000001285 99.0
PYH2_k127_9163560_7 Universal stress protein - - - 0.0000000000000000002128 93.0
PYH2_k127_9163560_8 PFAM biotin lipoyl attachment domain-containing protein - - - 0.000000000000000005158 88.0
PYH2_k127_9163560_9 Mo-molybdopterin cofactor metabolic process K00366,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,2.7.7.80,2.8.1.11 0.000000628 56.0
PYH2_k127_9193321_0 formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 392.0
PYH2_k127_9193321_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 323.0
PYH2_k127_9193321_2 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000003942 179.0
PYH2_k127_9193321_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000001708 145.0
PYH2_k127_9222712_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
PYH2_k127_9222712_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 363.0
PYH2_k127_9222712_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 355.0
PYH2_k127_9222712_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
PYH2_k127_9222712_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 291.0
PYH2_k127_9222712_5 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 285.0
PYH2_k127_9222712_6 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000001013 186.0
PYH2_k127_9222712_7 MFS_1 like family - - - 0.0000000000000000000000000000000000655 148.0
PYH2_k127_9222712_8 - - - - 0.0000000000000000000000000000000002137 145.0
PYH2_k127_9250360_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 336.0
PYH2_k127_9250360_1 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000007721 254.0
PYH2_k127_9250360_10 - - - - 0.0000000000000168 76.0
PYH2_k127_9250360_11 Domain of unknown function (DUF1508) K09946 - - 0.0000000000005972 70.0
PYH2_k127_9250360_12 Lipocalin-like domain - - - 0.0000000001461 66.0
PYH2_k127_9250360_13 Glycosyltransferase, group 2 family protein - - - 0.00001786 56.0
PYH2_k127_9250360_14 Lipocalin-like domain - - - 0.00005153 47.0
PYH2_k127_9250360_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000002099 211.0
PYH2_k127_9250360_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000002024 208.0
PYH2_k127_9250360_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000001796 205.0
PYH2_k127_9250360_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000447 161.0
PYH2_k127_9250360_6 BadF BadG BcrA BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000008639 158.0
PYH2_k127_9250360_7 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000006281 142.0
PYH2_k127_9250360_8 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.00000000000000000000000000000003121 134.0
PYH2_k127_9250360_9 RNA-binding protein contains TRAM domain - - - 0.0000000000000000004713 88.0
PYH2_k127_9289947_0 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000001822 210.0
PYH2_k127_9289947_1 ABC transporter permease K19976 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000002694 128.0
PYH2_k127_9289947_2 Spore germination protein K03294 - - 0.000000000000000000000003274 105.0
PYH2_k127_9289947_3 ubiquitin protein ligase activity K16276 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0019941,GO:0030003,GO:0030163,GO:0031667,GO:0031668,GO:0031669,GO:0032446,GO:0032501,GO:0033554,GO:0036211,GO:0042592,GO:0042594,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048871,GO:0048878,GO:0050801,GO:0050896,GO:0051603,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060586,GO:0061630,GO:0061659,GO:0065007,GO:0065008,GO:0070647,GO:0071496,GO:0071704,GO:0098771,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000132 48.0
PYH2_k127_937654_0 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 517.0
PYH2_k127_937654_1 Cupin domain - - - 0.0000000000000000000000000000000000000000002061 171.0
PYH2_k127_944143_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 5.419e-212 678.0
PYH2_k127_944143_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.458e-195 621.0
PYH2_k127_944143_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000002811 149.0
PYH2_k127_944143_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000007381 132.0
PYH2_k127_944143_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000003558 116.0
PYH2_k127_944143_5 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000001187 66.0
PYH2_k127_944143_6 TIGRFAM MoaD family protein K03636 - - 0.00000000004264 67.0
PYH2_k127_996353_0 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 328.0
PYH2_k127_996353_1 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000007303 98.0
PYH2_k127_996353_2 Cupin 2, conserved barrel domain protein - - - 0.0001951 44.0