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Overview

ID MAG03190
Name PYH2_bin.40
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Fen-1058
Family Fen-1058
Genus
Species
Assembly information
Completeness (%) 92.45
Contamination (%) 3.48
GC content (%) 64.0
N50 (bp) 10,863
Genome size (bp) 4,234,452

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3774

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1022391_0 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 563.0
PYH2_k127_1022391_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 515.0
PYH2_k127_1022391_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 483.0
PYH2_k127_1022391_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002573 244.0
PYH2_k127_1022391_4 YceI-like domain - - - 0.0000000000000000000000000000000000001505 144.0
PYH2_k127_1028296_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004343 259.0
PYH2_k127_1042965_0 pilus organization K02674,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 488.0
PYH2_k127_1042965_1 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 386.0
PYH2_k127_1054979_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1086.0
PYH2_k127_1054979_1 PFAM glycosyl transferase, family 51 - - - 1.483e-232 746.0
PYH2_k127_1054979_10 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006302 271.0
PYH2_k127_1054979_11 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000001395 265.0
PYH2_k127_1054979_12 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000002297 255.0
PYH2_k127_1054979_13 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000000000000000000000000000000000000000000000000000002473 228.0
PYH2_k127_1054979_14 PTS system sorbose-specific iic component K02795 - - 0.00000000000000000000000000000000000000000000000000000000000005297 224.0
PYH2_k127_1054979_15 2-dehydro-3-deoxy-phosphogluconate aldolase activity K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000003148 197.0
PYH2_k127_1054979_16 SIS domain - - - 0.00000000000000000000000000000000000000000000000000111 192.0
PYH2_k127_1054979_17 3-hexulose-6-phosphate synthase K08093 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 0.0000000000000000000000000000000000000000000000001036 184.0
PYH2_k127_1054979_18 protein containing SIS (Sugar isomerase) phosphosugar binding domain - - - 0.0000000000000000000000000000000000000000000000009629 184.0
PYH2_k127_1054979_19 UTRA K03710 - - 0.000000000000000000000000000000000000000000000002248 183.0
PYH2_k127_1054979_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.014e-197 631.0
PYH2_k127_1054979_20 glucose-6-phosphate isomerase K06859 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.00000000000000000000000000000000000000000002698 167.0
PYH2_k127_1054979_21 sugar phosphate isomerase involved in capsule formation - - - 0.00000000000000000000000000000000000000000177 164.0
PYH2_k127_1054979_22 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000001814 158.0
PYH2_k127_1054979_23 TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily - - - 0.00000000000000000000000000000000000001294 156.0
PYH2_k127_1054979_24 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000005501 143.0
PYH2_k127_1054979_25 - - - - 0.000000000000000000000000000000000007099 147.0
PYH2_k127_1054979_26 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000001056 150.0
PYH2_k127_1054979_27 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000008332 121.0
PYH2_k127_1054979_28 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000009198 112.0
PYH2_k127_1054979_29 system, fructose subfamily, IIA component K02793 - 2.7.1.191 0.000000000000000000000002566 107.0
PYH2_k127_1054979_3 succinate dehydrogenase K00244 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 503.0
PYH2_k127_1054979_30 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000009774 110.0
PYH2_k127_1054979_31 - - - - 0.00000000000000000000521 103.0
PYH2_k127_1054979_32 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000001382 83.0
PYH2_k127_1054979_33 toxin-antitoxin pair type II binding - - - 0.000000000001428 70.0
PYH2_k127_1054979_34 - - - - 0.00000000000975 75.0
PYH2_k127_1054979_4 cell wall glycoprotein biosynthetic process K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 428.0
PYH2_k127_1054979_5 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 377.0
PYH2_k127_1054979_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
PYH2_k127_1054979_7 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 295.0
PYH2_k127_1054979_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 286.0
PYH2_k127_1054979_9 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005126 281.0
PYH2_k127_1062800_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000005023 197.0
PYH2_k127_1067103_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 322.0
PYH2_k127_1067103_1 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000002423 188.0
PYH2_k127_1068833_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 439.0
PYH2_k127_1068833_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 318.0
PYH2_k127_1068833_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 315.0
PYH2_k127_1068833_3 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000006955 214.0
PYH2_k127_1068833_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000004392 184.0
PYH2_k127_1068833_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000004052 134.0
PYH2_k127_1068833_6 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000001774 126.0
PYH2_k127_1068833_7 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000003214 121.0
PYH2_k127_1068833_8 DinB superfamily - - - 0.00000004259 63.0
PYH2_k127_1068833_9 DinB superfamily - - - 0.000752 48.0
PYH2_k127_1069788_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 332.0
PYH2_k127_1069788_1 lipid binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004351 244.0
PYH2_k127_1069788_2 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000154 176.0
PYH2_k127_1069788_3 Domain of unknown function (DUF4342) - - - 0.000000000000002742 78.0
PYH2_k127_1071334_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 5.944e-246 785.0
PYH2_k127_1071334_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 562.0
PYH2_k127_1071334_10 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000004945 223.0
PYH2_k127_1071334_11 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000001192 199.0
PYH2_k127_1071334_12 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001877 187.0
PYH2_k127_1071334_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000001938 185.0
PYH2_k127_1071334_14 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000005894 175.0
PYH2_k127_1071334_15 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000004573 154.0
PYH2_k127_1071334_16 - - - - 0.00000000000000000000000000000001405 132.0
PYH2_k127_1071334_17 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000004471 105.0
PYH2_k127_1071334_18 Histidine kinase K07673 - 2.7.13.3 0.0000000000000002452 94.0
PYH2_k127_1071334_19 Transposase K07491 - - 0.000000000000004123 78.0
PYH2_k127_1071334_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 542.0
PYH2_k127_1071334_20 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.00000000000001566 88.0
PYH2_k127_1071334_21 FR47-like protein - - - 0.0000000000001072 77.0
PYH2_k127_1071334_23 YwiC-like protein - - - 0.00000000000875 76.0
PYH2_k127_1071334_24 iron dependent repressor K03709 - - 0.0000000006438 64.0
PYH2_k127_1071334_26 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000006903 66.0
PYH2_k127_1071334_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 495.0
PYH2_k127_1071334_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 475.0
PYH2_k127_1071334_5 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 417.0
PYH2_k127_1071334_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 370.0
PYH2_k127_1071334_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002722 271.0
PYH2_k127_1071334_8 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000003807 242.0
PYH2_k127_1071334_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
PYH2_k127_1078984_0 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000004455 185.0
PYH2_k127_1078984_1 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000002675 153.0
PYH2_k127_1078984_2 - - - - 0.00000000000000000002333 96.0
PYH2_k127_1080502_0 Integrase, catalytic region - - - 2.074e-201 631.0
PYH2_k127_1080502_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 290.0
PYH2_k127_1103789_0 ATPases associated with a variety of cellular activities K02028,K02030,K09972 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 405.0
PYH2_k127_1103789_1 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 403.0
PYH2_k127_1103789_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 376.0
PYH2_k127_1103789_3 Binding-protein-dependent transport system inner membrane component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 348.0
PYH2_k127_1103789_4 Belongs to the bacterial solute-binding protein 3 family K02030,K09969,K10039 - - 0.00000000000000000000000000000000000000000000002091 185.0
PYH2_k127_1111326_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 553.0
PYH2_k127_1111326_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000003453 258.0
PYH2_k127_1111326_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
PYH2_k127_1111326_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
PYH2_k127_1111326_4 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000002534 230.0
PYH2_k127_1111326_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000001426 189.0
PYH2_k127_1111326_6 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000001242 132.0
PYH2_k127_1111326_7 Membrane - - - 0.0000000000000000000000000000001785 140.0
PYH2_k127_1112883_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.532e-276 854.0
PYH2_k127_1112883_1 polysaccharide catabolic process K05991 - 3.2.1.123 1.328e-238 752.0
PYH2_k127_1112883_10 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 342.0
PYH2_k127_1112883_11 TIGRFAM dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001443 282.0
PYH2_k127_1112883_12 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000001019 262.0
PYH2_k127_1112883_13 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
PYH2_k127_1112883_14 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000002869 209.0
PYH2_k127_1112883_15 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000008939 178.0
PYH2_k127_1112883_16 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 - 2.1.1.182,2.1.1.184 0.0000000000000000000000000000000000000000000003981 174.0
PYH2_k127_1112883_17 PFAM nitrogen-fixing NifU domain protein K04488 - - 0.00000000000000000000000000004536 123.0
PYH2_k127_1112883_18 of nitrite reductase and ring-hydroxylating K05710 - - 0.0000000000000000000000000006391 116.0
PYH2_k127_1112883_19 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000004061 102.0
PYH2_k127_1112883_2 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 2.227e-238 745.0
PYH2_k127_1112883_20 succinate dehydrogenase K00241,K00247 - - 0.00000000000000000003604 99.0
PYH2_k127_1112883_21 DeoR-like helix-turn-helix domain - - - 0.0000000000000000009859 94.0
PYH2_k127_1112883_22 Pfam:DUF59 - - - 0.00000000000000001068 91.0
PYH2_k127_1112883_23 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00001217 53.0
PYH2_k127_1112883_3 Belongs to the PEP-utilizing enzyme family K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 3.882e-216 699.0
PYH2_k127_1112883_4 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 572.0
PYH2_k127_1112883_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 552.0
PYH2_k127_1112883_6 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 555.0
PYH2_k127_1112883_7 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
PYH2_k127_1112883_8 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 418.0
PYH2_k127_1112883_9 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 341.0
PYH2_k127_1122970_0 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 318.0
PYH2_k127_1122970_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000002377 108.0
PYH2_k127_1136363_0 NACHT domain - - - 0.000000000003979 79.0
PYH2_k127_1136363_1 C4-type zinc ribbon domain K07164 - - 0.0007442 43.0
PYH2_k127_1152413_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000003852 180.0
PYH2_k127_1156738_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 595.0
PYH2_k127_1156738_1 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000122 237.0
PYH2_k127_1177735_0 Molecular chaperone. Has ATPase activity K04079 - - 9.915e-215 683.0
PYH2_k127_1177735_1 Selenocysteine-specific translation elongation factor K03833 - - 2.14e-204 653.0
PYH2_k127_1177735_2 Tocopherol cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 327.0
PYH2_k127_1177735_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 304.0
PYH2_k127_1177735_4 peptidase - - - 0.00000000000000000000000000000000000000000002883 177.0
PYH2_k127_1177735_5 PFAM glycosyl transferase group 1 - - - 0.0000000000007863 71.0
PYH2_k127_1197354_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 447.0
PYH2_k127_1197354_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000001347 57.0
PYH2_k127_1197458_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 510.0
PYH2_k127_1197458_1 - - - - 0.0000000000000000000000000000000000000000101 158.0
PYH2_k127_1197458_2 nucleotidyltransferase activity - - - 0.0000005163 55.0
PYH2_k127_1213989_0 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 303.0
PYH2_k127_1213989_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000001979 62.0
PYH2_k127_1213989_2 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000377 49.0
PYH2_k127_1213989_3 OB-fold nucleic acid binding domain - - - 0.0001693 51.0
PYH2_k127_1240578_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 318.0
PYH2_k127_1240578_1 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000461 263.0
PYH2_k127_1240578_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000003982 237.0
PYH2_k127_1240578_3 response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000001053 240.0
PYH2_k127_1240578_4 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000004481 228.0
PYH2_k127_1240578_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000001946 61.0
PYH2_k127_1276599_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000002702 123.0
PYH2_k127_1276599_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000003156 66.0
PYH2_k127_1279883_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 341.0
PYH2_k127_1279883_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007147 272.0
PYH2_k127_1279883_2 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000007828 213.0
PYH2_k127_1279883_4 PIN domain - - - 0.0000000000003054 78.0
PYH2_k127_1279883_5 transposase activity - - - 0.0000000001219 64.0
PYH2_k127_1279883_6 Carboxypeptidase regulatory-like domain - - - 0.0000001151 65.0
PYH2_k127_1279883_7 - - - - 0.0000006305 55.0
PYH2_k127_1279883_8 PFAM transposase, IS4 family protein - - - 0.00002315 47.0
PYH2_k127_1289808_0 Nitrous oxide reductase K00376 - 1.7.2.4 5.338e-297 921.0
PYH2_k127_1289808_1 alginic acid biosynthetic process K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 375.0
PYH2_k127_1289808_2 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000000000000000000000004681 221.0
PYH2_k127_1295956_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 516.0
PYH2_k127_1295956_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 421.0
PYH2_k127_1295956_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000003116 108.0
PYH2_k127_1295956_3 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.00000008619 54.0
PYH2_k127_1357244_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 426.0
PYH2_k127_1357244_1 Thermolysin metallopeptidase, catalytic domain K01400,K08777 GO:0005575,GO:0005576 3.4.24.28 0.000000000000000000000000000000000000000000005777 189.0
PYH2_k127_1357244_2 Thrombospondin K04659,K16857 GO:0000187,GO:0000302,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001786,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001937,GO:0001944,GO:0001952,GO:0001953,GO:0001968,GO:0002040,GO:0002376,GO:0002544,GO:0002576,GO:0002577,GO:0002578,GO:0002580,GO:0002581,GO:0002604,GO:0002605,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003007,GO:0003151,GO:0003197,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005543,GO:0005575,GO:0005576,GO:0005577,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006417,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006911,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007049,GO:0007050,GO:0007155,GO:0007162,GO:0007275,GO:0007507,GO:0007610,GO:0008150,GO:0008152,GO:0008201,GO:0008284,GO:0008285,GO:0008289,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010324,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010596,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010746,GO:0010748,GO:0010749,GO:0010751,GO:0010752,GO:0010754,GO:0010755,GO:0010757,GO:0010758,GO:0010759,GO:0010762,GO:0010763,GO:0010810,GO:0010811,GO:0010812,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0017015,GO:0017134,GO:0018149,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0022402,GO:0022603,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030155,GO:0030162,GO:0030169,GO:0030193,GO:0030194,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030511,GO:0031012,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032026,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032570,GO:0032655,GO:0032680,GO:0032695,GO:0032760,GO:0032879,GO:0032890,GO:0032891,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033554,GO:0033555,GO:0033674,GO:0033993,GO:0034248,GO:0034250,GO:0034284,GO:0034599,GO:0034605,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0034774,GO:0034976,GO:0035239,GO:0035265,GO:0035295,GO:0035690,GO:0036211,GO:0036293,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040036,GO:0040037,GO:0042035,GO:0042108,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042534,GO:0042535,GO:0042802,GO:0042981,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043236,GO:0043269,GO:0043271,GO:0043277,GO:0043281,GO:0043394,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043535,GO:0043536,GO:0043537,GO:0043549,GO:0043652,GO:0044070,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045765,GO:0045766,GO:0045785,GO:0045786,GO:0045859,GO:0045860,GO:0045861,GO:0045937,GO:0046872,GO:0046903,GO:0048265,GO:0048266,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048660,GO:0048661,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050818,GO:0050820,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051049,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051592,GO:0051674,GO:0051716,GO:0051726,GO:0051893,GO:0051895,GO:0051896,GO:0051897,GO:0051917,GO:0051918,GO:0051960,GO:0051962,GO:0051963,GO:0051965,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0060548,GO:0061024,GO:0061041,GO:0061448,GO:0062023,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070051,GO:0070052,GO:0070482,GO:0070613,GO:0070887,GO:0071241,GO:0071622,GO:0071634,GO:0071636,GO:0071675,GO:0071704,GO:0071731,GO:0071732,GO:0071813,GO:0071814,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072341,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090109,GO:0090287,GO:0090288,GO:0090303,GO:0097366,GO:0097367,GO:0097708,GO:0098552,GO:0098657,GO:0098868,GO:0099024,GO:0099503,GO:1900046,GO:1900048,GO:1901342,GO:1901343,GO:1901564,GO:1901654,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1902041,GO:1902043,GO:1902170,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903317,GO:1903318,GO:1903391,GO:1903392,GO:1903555,GO:1903557,GO:1903587,GO:1903588,GO:1903670,GO:1903671,GO:1903706,GO:1903792,GO:1903844,GO:1903846,GO:1903959,GO:1903960,GO:1904018,GO:1904035,GO:1904037,GO:1905521,GO:1905523,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000191,GO:2000192,GO:2000351,GO:2000353,GO:2000377,GO:2000379,GO:2001026,GO:2001027,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238 - 0.00000000000000000000000000000000000000994 169.0
PYH2_k127_1357244_3 O-methyltransferase, family 2 - - - 0.000000000000000000002097 106.0
PYH2_k127_1357244_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000004536 85.0
PYH2_k127_1357244_5 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000001397 64.0
PYH2_k127_1357244_7 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0000006807 54.0
PYH2_k127_136058_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1356.0
PYH2_k127_136058_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 8.786e-307 957.0
PYH2_k127_136058_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001926 80.0
PYH2_k127_136058_11 DNA alkylation repair enzyme - - - 0.0001013 53.0
PYH2_k127_136058_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.613e-260 820.0
PYH2_k127_136058_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000002723 232.0
PYH2_k127_136058_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002166 197.0
PYH2_k127_136058_5 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000001238 199.0
PYH2_k127_136058_6 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000001083 186.0
PYH2_k127_136058_7 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000008541 173.0
PYH2_k127_136058_9 serine threonine protein kinase - - - 0.00000000000000003862 89.0
PYH2_k127_1367082_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 561.0
PYH2_k127_1367082_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 421.0
PYH2_k127_1367082_11 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000000004888 91.0
PYH2_k127_1367082_12 PFAM Forkhead-associated protein - - - 0.000000000000000197 86.0
PYH2_k127_1367082_14 toxin-antitoxin pair type II binding - - - 0.0000000000005755 71.0
PYH2_k127_1367082_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 412.0
PYH2_k127_1367082_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
PYH2_k127_1367082_4 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 295.0
PYH2_k127_1367082_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002529 276.0
PYH2_k127_1367082_6 transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000811 264.0
PYH2_k127_1367082_7 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000003911 241.0
PYH2_k127_1367082_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000003375 123.0
PYH2_k127_1367082_9 PFAM PHA accumulation regulator DNA-binding protein - - - 0.00000000000000000000000000006869 127.0
PYH2_k127_1385686_0 Sulfate permease K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 439.0
PYH2_k127_1385686_1 - K09712,K14475 - - 0.000000000000000000000000000003812 136.0
PYH2_k127_1385686_2 response to heat K03668,K09914 - - 0.00000000000000535 88.0
PYH2_k127_1400243_0 elongation factor Tu domain 2 protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 520.0
PYH2_k127_1400243_1 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 450.0
PYH2_k127_1400243_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0000000000000000000005069 97.0
PYH2_k127_1409428_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 481.0
PYH2_k127_1409428_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 429.0
PYH2_k127_1409428_2 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002995 280.0
PYH2_k127_1409428_3 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000001426 207.0
PYH2_k127_1409428_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000004759 178.0
PYH2_k127_1409428_5 Histidine kinase K20976 - - 0.00000000000000000003176 94.0
PYH2_k127_1457623_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 3.808e-202 638.0
PYH2_k127_1457623_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 556.0
PYH2_k127_1457623_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 553.0
PYH2_k127_1457623_3 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 406.0
PYH2_k127_1457623_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 325.0
PYH2_k127_1457623_5 Maltose acetyltransferase K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 304.0
PYH2_k127_1457623_6 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001636 245.0
PYH2_k127_1457623_7 Transglutaminase-like superfamily - - - 0.0000000000000135 79.0
PYH2_k127_1457623_8 PBS lyase HEAT-like repeat - - - 0.0000000000006216 81.0
PYH2_k127_1457623_9 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.00000000002195 70.0
PYH2_k127_1465543_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1189.0
PYH2_k127_1465543_1 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 345.0
PYH2_k127_1465543_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 340.0
PYH2_k127_1465543_3 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009904 276.0
PYH2_k127_1465543_4 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000005501 210.0
PYH2_k127_1465543_5 phosphatase K04459,K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000000000000000000000000000005672 173.0
PYH2_k127_1465543_6 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000107 108.0
PYH2_k127_1465543_7 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000002679 85.0
PYH2_k127_1466557_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 545.0
PYH2_k127_1466557_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000004533 230.0
PYH2_k127_1466557_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000006383 188.0
PYH2_k127_1466557_3 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000008713 155.0
PYH2_k127_1466557_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000002673 124.0
PYH2_k127_1473527_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 451.0
PYH2_k127_1473527_1 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 449.0
PYH2_k127_1473527_10 sh3 domain protein K01227,K03642 - 3.2.1.96 0.000000000000000000000000000000000002728 150.0
PYH2_k127_1473527_11 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000001296 98.0
PYH2_k127_1473527_2 PFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 275.0
PYH2_k127_1473527_3 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.0000000000000000000000000000000000000000000000000000000000000000002508 242.0
PYH2_k127_1473527_4 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000002638 220.0
PYH2_k127_1473527_5 - - - - 0.00000000000000000000000000000000000000000000000000004409 205.0
PYH2_k127_1473527_6 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000008631 170.0
PYH2_k127_1473527_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000002511 167.0
PYH2_k127_1473527_8 exodeoxyribonuclease I activity - - - 0.000000000000000000000000000000000000000000004188 169.0
PYH2_k127_1473527_9 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000001271 158.0
PYH2_k127_1498274_0 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 393.0
PYH2_k127_1498274_1 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 378.0
PYH2_k127_1498274_2 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 313.0
PYH2_k127_1498274_3 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 302.0
PYH2_k127_1498274_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004181 283.0
PYH2_k127_1504285_0 ankyrin repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000253 236.0
PYH2_k127_1504285_1 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000000000000000000000008714 223.0
PYH2_k127_1504285_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000005555 179.0
PYH2_k127_1504285_3 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000001769 140.0
PYH2_k127_1504285_4 viral genome integration into host DNA - - - 0.0000879 45.0
PYH2_k127_1531928_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1040.0
PYH2_k127_1531928_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.588e-205 651.0
PYH2_k127_1531928_2 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
PYH2_k127_1531928_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000006077 186.0
PYH2_k127_1531928_4 acetyltransferase K00950,K03789,K03823 - 2.3.1.128,2.3.1.183,2.7.6.3 0.000000000000000000000000000000000000002716 163.0
PYH2_k127_1531928_5 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000004483 108.0
PYH2_k127_1552074_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000001839 240.0
PYH2_k127_1552074_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000007429 207.0
PYH2_k127_1552074_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000005553 142.0
PYH2_k127_1552074_3 - - - - 0.000000000000002805 82.0
PYH2_k127_1552074_4 extracellular solute-binding protein, family 3 K02030 - - 0.000000000002419 70.0
PYH2_k127_1552074_5 histidine kinase HAMP region domain protein - - - 0.0000000004453 61.0
PYH2_k127_1556737_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.962e-211 667.0
PYH2_k127_1556737_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
PYH2_k127_1556737_2 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000002047 209.0
PYH2_k127_1556737_3 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000003767 203.0
PYH2_k127_1556737_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000001022 141.0
PYH2_k127_1556737_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001341 136.0
PYH2_k127_1556737_6 Two component transcriptional regulator, winged helix family - - - 0.00000000009135 65.0
PYH2_k127_1559796_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 510.0
PYH2_k127_1559796_1 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000006914 236.0
PYH2_k127_1559796_2 Pterin binding enzyme K15023 - 2.1.1.258 0.000008774 49.0
PYH2_k127_1575858_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 4.939e-224 728.0
PYH2_k127_1575858_1 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 311.0
PYH2_k127_1575858_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000005713 229.0
PYH2_k127_1575858_3 - - - - 0.0000000000000000000000000000000000009704 152.0
PYH2_k127_1591588_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 517.0
PYH2_k127_1591588_1 pilus organization K02674,K07004 - - 0.00000000000000000000000000002692 121.0
PYH2_k127_1632985_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
PYH2_k127_1632985_1 cystathionine K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001686 281.0
PYH2_k127_1632985_2 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000006201 207.0
PYH2_k127_1632985_3 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000006704 158.0
PYH2_k127_1632985_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000251 162.0
PYH2_k127_1632985_5 Nudix hydrolase - - - 0.000000000000000000000000000000000000034 151.0
PYH2_k127_1632985_6 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000001532 137.0
PYH2_k127_1632985_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000003652 91.0
PYH2_k127_1634206_0 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 293.0
PYH2_k127_1634206_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000003463 247.0
PYH2_k127_1634206_2 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000004503 200.0
PYH2_k127_1634206_3 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000005071 181.0
PYH2_k127_1634206_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000004976 78.0
PYH2_k127_1634206_5 - - - - 0.0000000006575 67.0
PYH2_k127_1634206_7 PFAM Transposase, IS66 K07484 - - 0.00001565 51.0
PYH2_k127_1634935_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 486.0
PYH2_k127_1634935_1 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 372.0
PYH2_k127_1634935_10 - - - - 0.000000000000000000000003804 111.0
PYH2_k127_1634935_11 - - - - 0.000000000002463 75.0
PYH2_k127_1634935_12 PFAM Forkhead-associated protein - - - 0.00000000218 71.0
PYH2_k127_1634935_2 MutL protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 329.0
PYH2_k127_1634935_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 296.0
PYH2_k127_1634935_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000762 253.0
PYH2_k127_1634935_5 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002321 229.0
PYH2_k127_1634935_6 - - - - 0.0000000000000000000000000000000000000000006018 169.0
PYH2_k127_1634935_7 Protein of unknown function (DUF2723) K14340 - - 0.00000000000000000000000000000000008816 154.0
PYH2_k127_1634935_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000128 143.0
PYH2_k127_1634935_9 - - - - 0.0000000000000000000000006979 115.0
PYH2_k127_1641817_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 5.8e-249 782.0
PYH2_k127_1641817_1 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 451.0
PYH2_k127_1641817_2 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 333.0
PYH2_k127_1641817_3 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 265.0
PYH2_k127_1641817_4 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000002248 191.0
PYH2_k127_1641817_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000009217 187.0
PYH2_k127_1641817_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000165 178.0
PYH2_k127_1641817_7 Glutamate synthase - - - 0.00000000000000000000000000000001023 139.0
PYH2_k127_1641817_8 PFAM chemotaxis K03406,K07216 - - 0.00000000174 70.0
PYH2_k127_1641817_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000002565 64.0
PYH2_k127_1642954_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 2.137e-247 784.0
PYH2_k127_1642954_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 332.0
PYH2_k127_1642954_2 - - - - 0.0009359 48.0
PYH2_k127_1658476_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1043.0
PYH2_k127_1658476_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000008137 216.0
PYH2_k127_1658476_2 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000000000005819 133.0
PYH2_k127_1658476_3 PFAM Acetyltransferase (GNAT) family K03824 - - 0.00000419 49.0
PYH2_k127_1658476_4 AntiSigma factor - - - 0.00005363 51.0
PYH2_k127_1660763_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 337.0
PYH2_k127_1660763_1 PFAM glycosyl transferase group 1 K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 312.0
PYH2_k127_1660763_2 Membrane - - - 0.0000000000000001424 94.0
PYH2_k127_1660763_3 Uncharacterised nucleotidyltransferase - - - 0.00000002103 66.0
PYH2_k127_1660763_4 - - - - 0.00001683 57.0
PYH2_k127_168177_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 5.044e-194 610.0
PYH2_k127_168177_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000003453 194.0
PYH2_k127_168177_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000001409 155.0
PYH2_k127_168177_3 PFAM PilT protein domain protein - - - 0.00000000000000000000000002129 110.0
PYH2_k127_168177_4 - - - - 0.0000000000000005399 82.0
PYH2_k127_168177_5 DNA-binding transcription factor activity K03892 - - 0.0000000000001147 75.0
PYH2_k127_1682381_0 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 534.0
PYH2_k127_1682381_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000003684 193.0
PYH2_k127_1682381_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000003014 98.0
PYH2_k127_1682933_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 8.303e-223 743.0
PYH2_k127_1682933_1 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K02293 - 1.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 587.0
PYH2_k127_1682933_10 - - - - 0.000000000000003695 76.0
PYH2_k127_1682933_11 UbiA prenyltransferase family K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000223 83.0
PYH2_k127_1682933_12 - - - - 0.000000000003247 70.0
PYH2_k127_1682933_13 - - - - 0.000000000006031 66.0
PYH2_k127_1682933_14 COG NOG15344 non supervised orthologous group - - - 0.00000000002421 65.0
PYH2_k127_1682933_16 - - - - 0.00000000003951 64.0
PYH2_k127_1682933_19 non supervised orthologous group - - - 0.000000006946 63.0
PYH2_k127_1682933_2 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000001452 171.0
PYH2_k127_1682933_20 Unextendable partial coding region - - - 0.0000002615 54.0
PYH2_k127_1682933_22 Uncharacterised protein, DegV family COG1307 - - - 0.00000269 55.0
PYH2_k127_1682933_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00001535 53.0
PYH2_k127_1682933_3 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000000000000000001646 149.0
PYH2_k127_1682933_4 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000000000000003009 139.0
PYH2_k127_1682933_5 - - - - 0.000000000000000000000000000000004391 129.0
PYH2_k127_1682933_6 - - - - 0.00000000000000000000000000000002249 129.0
PYH2_k127_1682933_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000008787 126.0
PYH2_k127_1682933_8 - - - - 0.00000000000000006673 83.0
PYH2_k127_1702964_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 515.0
PYH2_k127_1702964_1 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 344.0
PYH2_k127_1702964_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000006685 152.0
PYH2_k127_1702964_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000004528 134.0
PYH2_k127_1702964_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001311 129.0
PYH2_k127_1702964_5 Belongs to the UPF0109 family K06960 - - 0.000000000000000001915 93.0
PYH2_k127_1716651_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 312.0
PYH2_k127_1716651_1 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000001663 226.0
PYH2_k127_1724211_0 Cytochrome D1 heme domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 294.0
PYH2_k127_1724211_1 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005641 267.0
PYH2_k127_1724211_2 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000007186 166.0
PYH2_k127_1724211_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000006007 149.0
PYH2_k127_1724211_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.000000000000000000000000004351 119.0
PYH2_k127_1729466_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 550.0
PYH2_k127_1729466_1 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.000000000000000000000000000000000000008798 151.0
PYH2_k127_1761086_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 331.0
PYH2_k127_1761086_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000002181 219.0
PYH2_k127_1761086_2 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000003096 205.0
PYH2_k127_1761086_3 nucleic-acid-binding protein contains PIN domain - - - 0.0005913 44.0
PYH2_k127_1778221_0 Membrane - - - 0.000000000009897 79.0
PYH2_k127_1778221_1 Membrane - - - 0.000000000068 68.0
PYH2_k127_1778221_2 Bacterial membrane protein, YfhO - - - 0.0006232 53.0
PYH2_k127_1787776_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 582.0
PYH2_k127_1787776_1 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 392.0
PYH2_k127_1787776_2 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 378.0
PYH2_k127_1787776_3 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000009271 149.0
PYH2_k127_1787776_4 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000006194 141.0
PYH2_k127_1787776_5 Belongs to the P(II) protein family - - - 0.00000000000000003757 87.0
PYH2_k127_180429_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 333.0
PYH2_k127_180429_1 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 330.0
PYH2_k127_180429_2 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 293.0
PYH2_k127_180429_3 reverse transcriptase K00986 - 2.7.7.49 0.00000000000001168 76.0
PYH2_k127_180429_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000003301 74.0
PYH2_k127_1804919_0 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
PYH2_k127_1804919_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 498.0
PYH2_k127_1804919_10 protein with SCP PR1 domains - - - 0.00000000000000000000003646 106.0
PYH2_k127_1804919_11 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000003583 49.0
PYH2_k127_1804919_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 423.0
PYH2_k127_1804919_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 366.0
PYH2_k127_1804919_4 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 314.0
PYH2_k127_1804919_5 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 314.0
PYH2_k127_1804919_6 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000004115 231.0
PYH2_k127_1804919_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000259 218.0
PYH2_k127_1804919_8 Periplasmic binding protein domain K10546 - - 0.0000000000000000000000000000000001437 135.0
PYH2_k127_1804919_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000006912 102.0
PYH2_k127_1828546_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 526.0
PYH2_k127_1828546_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 361.0
PYH2_k127_1828546_10 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000004061 129.0
PYH2_k127_1828546_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000003805 124.0
PYH2_k127_1828546_12 subunit of a heme lyase K02200 - - 0.00000000000000000000000000004442 122.0
PYH2_k127_1828546_13 PFAM YhhN family protein - - - 0.0000000000000000000000000002337 126.0
PYH2_k127_1828546_14 CoA binding domain - - - 0.0000000000000000000000001453 114.0
PYH2_k127_1828546_15 Bacterial regulatory proteins, crp family K10914 - - 0.000000000000000002591 91.0
PYH2_k127_1828546_16 zinc-ribbon domain - - - 0.00000002131 62.0
PYH2_k127_1828546_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000103 60.0
PYH2_k127_1828546_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 315.0
PYH2_k127_1828546_3 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000002021 246.0
PYH2_k127_1828546_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000002868 248.0
PYH2_k127_1828546_5 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000003915 224.0
PYH2_k127_1828546_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000002937 210.0
PYH2_k127_1828546_7 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000003889 206.0
PYH2_k127_1828546_8 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000003911 202.0
PYH2_k127_1828546_9 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000006874 147.0
PYH2_k127_1841570_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 9.95e-198 631.0
PYH2_k127_1841570_1 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 353.0
PYH2_k127_1841570_10 Transposase IS200 like - - - 0.00000000000000001289 89.0
PYH2_k127_1841570_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000001286 84.0
PYH2_k127_1841570_12 Protein of unknown function (DUF1232) - - - 0.00000006533 59.0
PYH2_k127_1841570_13 Protein of unknown function (DUF1232) - - - 0.0000002914 59.0
PYH2_k127_1841570_14 PFAM GCN5-related N-acetyltransferase - - - 0.00001355 51.0
PYH2_k127_1841570_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03546,K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 336.0
PYH2_k127_1841570_3 fructosamine-3-kinase activity - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 295.0
PYH2_k127_1841570_4 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000002016 263.0
PYH2_k127_1841570_5 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006628 238.0
PYH2_k127_1841570_6 Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000051 241.0
PYH2_k127_1841570_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000001121 212.0
PYH2_k127_1841570_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000004121 164.0
PYH2_k127_1841570_9 3-hydroxybutyryl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000007748 153.0
PYH2_k127_18463_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 621.0
PYH2_k127_1848320_0 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 451.0
PYH2_k127_1848320_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 441.0
PYH2_k127_1848320_10 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007002 258.0
PYH2_k127_1848320_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001271 257.0
PYH2_k127_1848320_12 nodulation - - - 0.000000000000000000000000000000000000000000000000000000000000009328 231.0
PYH2_k127_1848320_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000007638 210.0
PYH2_k127_1848320_14 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000001187 207.0
PYH2_k127_1848320_15 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000246 204.0
PYH2_k127_1848320_16 lyase activity - - - 0.00000000000000000000000000000000000000000000000005996 184.0
PYH2_k127_1848320_17 SPTR NmrA family protein - - - 0.000000000000000000000000000000000000000000000001167 185.0
PYH2_k127_1848320_18 Methyltransferase domain K06987 - - 0.00000000000000000000000000000000000000000000001259 181.0
PYH2_k127_1848320_19 Methyltransferase - - - 0.000000000000000000000000000000000000000000003553 172.0
PYH2_k127_1848320_2 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 442.0
PYH2_k127_1848320_20 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000003798 153.0
PYH2_k127_1848320_21 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000000885 148.0
PYH2_k127_1848320_23 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000005303 125.0
PYH2_k127_1848320_24 Cytochrome c K00406 - - 0.00000000000000000000000003584 117.0
PYH2_k127_1848320_25 - - - - 0.0000000000000001474 84.0
PYH2_k127_1848320_26 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000001506 89.0
PYH2_k127_1848320_27 PFAM alpha beta hydrolase fold - - - 0.00000000000004053 77.0
PYH2_k127_1848320_28 GNAT acetyltransferase - - - 0.000000000005479 70.0
PYH2_k127_1848320_29 ATPases associated with a variety of cellular activities K01990 - - 0.00000000002646 71.0
PYH2_k127_1848320_3 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 351.0
PYH2_k127_1848320_30 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000004472 65.0
PYH2_k127_1848320_31 Peptidase, M28 - - - 0.00000000522 70.0
PYH2_k127_1848320_32 Tricorn protease C1 domain K03797 - 3.4.21.102 0.00000006016 57.0
PYH2_k127_1848320_33 carboxylic ester hydrolase activity - - - 0.0000006388 61.0
PYH2_k127_1848320_34 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000001053 54.0
PYH2_k127_1848320_35 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000001716 55.0
PYH2_k127_1848320_36 Putative auto-transporter adhesin, head GIN domain - - - 0.00000221 58.0
PYH2_k127_1848320_37 DinB superfamily - - - 0.000002243 56.0
PYH2_k127_1848320_38 periplasmic lipoprotein involved in iron transport K07224 - - 0.000003938 55.0
PYH2_k127_1848320_39 Beta-lactamase - - - 0.00000606 50.0
PYH2_k127_1848320_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 330.0
PYH2_k127_1848320_40 PFAM alpha beta hydrolase fold - - - 0.0002263 45.0
PYH2_k127_1848320_41 KR domain - - - 0.0005953 46.0
PYH2_k127_1848320_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 307.0
PYH2_k127_1848320_6 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 315.0
PYH2_k127_1848320_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
PYH2_k127_1848320_8 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 291.0
PYH2_k127_1848320_9 Pyruvate phosphate dikinase, PEP pyruvate binding K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000341 269.0
PYH2_k127_1868467_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 565.0
PYH2_k127_1868467_1 Haloacid dehalogenase-like hydrolase K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000006108 241.0
PYH2_k127_1868467_2 PFAM SMC domain protein K03546 - - 0.00000000000000000000000000000000000000000000000000000000003877 222.0
PYH2_k127_1870301_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.296e-286 902.0
PYH2_k127_1870301_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000003134 244.0
PYH2_k127_1870301_2 membrane - - - 0.000000000000000000000000008669 122.0
PYH2_k127_1870301_3 membrane K11622 - - 0.000000000000000002021 96.0
PYH2_k127_1876547_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 5.191e-272 857.0
PYH2_k127_1876547_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 7.446e-232 736.0
PYH2_k127_1876547_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 429.0
PYH2_k127_1876547_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 378.0
PYH2_k127_1876547_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
PYH2_k127_1876547_5 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 321.0
PYH2_k127_1876547_6 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000001905 183.0
PYH2_k127_1876547_7 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000003095 138.0
PYH2_k127_1876547_8 Succinyl-CoA ligase like flavodoxin domain - - - 0.00001502 48.0
PYH2_k127_1910537_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 379.0
PYH2_k127_1910537_1 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 361.0
PYH2_k127_1910537_2 PFAM AMP-dependent synthetase and ligase K00666,K01897,K18661 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 372.0
PYH2_k127_1910537_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000009823 237.0
PYH2_k127_1913407_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 481.0
PYH2_k127_1913407_1 - - - - 0.0000000000000000000000000000000009572 133.0
PYH2_k127_1939532_0 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 561.0
PYH2_k127_1939532_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 450.0
PYH2_k127_1939532_2 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000664 102.0
PYH2_k127_1942857_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 596.0
PYH2_k127_1942857_1 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 388.0
PYH2_k127_1942857_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 375.0
PYH2_k127_1942857_3 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001168 249.0
PYH2_k127_1942857_4 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000001028 175.0
PYH2_k127_1942857_5 Rieske [2Fe-2S] domain K03886 - - 0.000000000000000000000000001305 117.0
PYH2_k127_1942857_6 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.000000000000000000000000005675 128.0
PYH2_k127_1942857_7 Cytochrome C oxidase, cbb3-type, subunit III K00406,K03889 - - 0.00000000000000001241 98.0
PYH2_k127_1942857_8 helix_turn_helix, Lux Regulon K02479,K07675,K11623 - 2.7.13.3 0.00000000000000001277 84.0
PYH2_k127_1942857_9 Cytochrome c - - - 0.00000006887 65.0
PYH2_k127_1952021_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 377.0
PYH2_k127_1952021_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000004869 214.0
PYH2_k127_1952021_2 ABC transporter substrate binding protein K01989 - - 0.00000000000007755 71.0
PYH2_k127_1988115_0 Aminotransferase class-V K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 565.0
PYH2_k127_1988115_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 437.0
PYH2_k127_1988115_10 Ligated ion channel L-glutamate- and glycine-binding site K02030 - - 0.0001273 45.0
PYH2_k127_1988115_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 377.0
PYH2_k127_1988115_3 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 341.0
PYH2_k127_1988115_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 344.0
PYH2_k127_1988115_5 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001513 247.0
PYH2_k127_1988115_6 Binding-protein-dependent transport system inner membrane component K01284,K02029 - 3.4.15.5 0.00000000000000000000000000000000000000000000000000000000000000000055 240.0
PYH2_k127_1988115_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004499 229.0
PYH2_k127_1988115_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000866 163.0
PYH2_k127_1988115_9 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000003586 128.0
PYH2_k127_1990728_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1064.0
PYH2_k127_1990728_1 Putative cyclase - - - 2.96e-322 992.0
PYH2_k127_1990728_10 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 390.0
PYH2_k127_1990728_11 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 383.0
PYH2_k127_1990728_12 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 379.0
PYH2_k127_1990728_13 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 366.0
PYH2_k127_1990728_14 xanthine dehydrogenase activity K03519,K19818 - 1.2.5.3,1.5.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 354.0
PYH2_k127_1990728_15 PFAM NmrA family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007935 273.0
PYH2_k127_1990728_16 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007899 251.0
PYH2_k127_1990728_17 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000000000000000000000000000000000002086 232.0
PYH2_k127_1990728_18 CoA carboxylase activity K01615,K01965,K02160,K17490 - 2.1.3.1,4.1.1.70,6.4.1.3 0.0000000000000000000000000000000001045 139.0
PYH2_k127_1990728_19 Protein of unknown function (DUF1572) - - - 0.0000000000000000004196 94.0
PYH2_k127_1990728_2 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.664e-245 781.0
PYH2_k127_1990728_3 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 5.316e-200 637.0
PYH2_k127_1990728_4 CoA-ligase K02381 - - 2.465e-194 617.0
PYH2_k127_1990728_5 Protein of unknown function (DUF1116) - - - 2.558e-194 613.0
PYH2_k127_1990728_6 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 577.0
PYH2_k127_1990728_7 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 542.0
PYH2_k127_1990728_8 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 540.0
PYH2_k127_1990728_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 516.0
PYH2_k127_1993139_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.928e-249 780.0
PYH2_k127_1993139_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 473.0
PYH2_k127_1993139_2 SLBB domain K02237 - - 0.00000000000000000000000000000000004425 144.0
PYH2_k127_1993139_3 Putative heavy-metal-binding - - - 0.0000001062 57.0
PYH2_k127_1996203_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
PYH2_k127_1996203_1 Flavin reductase like domain - - - 0.000000000000000000000000000000000006603 142.0
PYH2_k127_1996203_2 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000000001809 109.0
PYH2_k127_1996203_3 helix-turn-helix domain protein - - - 0.0000000000000000003806 91.0
PYH2_k127_1996203_4 PFAM PspC domain K03973 - - 0.000000000000000001861 89.0
PYH2_k127_2002027_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 551.0
PYH2_k127_2002027_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 447.0
PYH2_k127_2002027_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 357.0
PYH2_k127_2002027_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000003013 237.0
PYH2_k127_2002027_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001769 228.0
PYH2_k127_2002027_5 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000003859 176.0
PYH2_k127_2002027_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000006774 101.0
PYH2_k127_2002027_7 histidine kinase A domain protein - - - 0.00000000000001054 88.0
PYH2_k127_2002027_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000009912 75.0
PYH2_k127_2002027_9 Redoxin K03564 - 1.11.1.15 0.00001132 51.0
PYH2_k127_2011015_0 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000000000000001929 228.0
PYH2_k127_2011015_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000021 143.0
PYH2_k127_2024197_0 Mannosyl oligosaccharide glucosidase - - - 0.0 1271.0
PYH2_k127_2024197_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.025e-198 625.0
PYH2_k127_2024197_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 457.0
PYH2_k127_2024197_3 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 314.0
PYH2_k127_2024197_4 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001587 244.0
PYH2_k127_2024197_5 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.000000000000000000000000000000002558 132.0
PYH2_k127_2024197_6 Transmembrane anti-sigma factor - - - 0.0000000000000000006834 89.0
PYH2_k127_2024197_7 ATPase P-type (Transporting), HAD superfamily, subfamily IC K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 0.00001271 50.0
PYH2_k127_2059692_0 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 491.0
PYH2_k127_2059692_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006786 268.0
PYH2_k127_2059692_2 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002981 266.0
PYH2_k127_2059692_3 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000004101 156.0
PYH2_k127_2059692_4 bacterial-type flagellum-dependent cell motility - - - 0.000005759 57.0
PYH2_k127_2061948_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.306e-231 726.0
PYH2_k127_2061948_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 565.0
PYH2_k127_2061948_2 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000002869 74.0
PYH2_k127_2069504_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 439.0
PYH2_k127_2069504_1 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 317.0
PYH2_k127_2069504_2 pilus organization K02674,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000001306 244.0
PYH2_k127_2069504_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000002987 169.0
PYH2_k127_2069504_4 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001303 151.0
PYH2_k127_2069504_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000001434 139.0
PYH2_k127_2069504_7 Dehydrogenase K00087,K03518 - 1.17.1.4,1.2.5.3 0.00000000000000001309 85.0
PYH2_k127_2069504_8 Transcriptional regulator - - - 0.0000000003501 66.0
PYH2_k127_2069504_9 Flavodoxin domain K00230 - 1.3.5.3 0.00000003262 63.0
PYH2_k127_2091602_0 secondary active sulfate transmembrane transporter activity K03321 - - 3.097e-213 685.0
PYH2_k127_2091602_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 475.0
PYH2_k127_2091602_2 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 390.0
PYH2_k127_2091602_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000145 153.0
PYH2_k127_2091602_4 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000001429 136.0
PYH2_k127_2091602_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000009894 69.0
PYH2_k127_2091602_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000003201 70.0
PYH2_k127_2093094_0 Fungalysin/Thermolysin Propeptide Motif K08603 - 3.4.24.27 1.774e-319 1000.0
PYH2_k127_2093094_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 527.0
PYH2_k127_2093094_10 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005123 261.0
PYH2_k127_2093094_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004096 253.0
PYH2_k127_2093094_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
PYH2_k127_2093094_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000006431 204.0
PYH2_k127_2093094_14 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000007005 148.0
PYH2_k127_2093094_15 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000001233 103.0
PYH2_k127_2093094_16 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000008694 91.0
PYH2_k127_2093094_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000007778 68.0
PYH2_k127_2093094_18 PFAM CBS domain containing protein K04767 - - 0.000000003029 62.0
PYH2_k127_2093094_19 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00001492 55.0
PYH2_k127_2093094_2 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 533.0
PYH2_k127_2093094_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 430.0
PYH2_k127_2093094_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 409.0
PYH2_k127_2093094_5 PFAM peptidase S58, DmpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 398.0
PYH2_k127_2093094_6 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 377.0
PYH2_k127_2093094_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 327.0
PYH2_k127_2093094_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 315.0
PYH2_k127_2093094_9 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 300.0
PYH2_k127_2109847_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 9.984e-265 840.0
PYH2_k127_2109847_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.645e-200 629.0
PYH2_k127_2109847_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001171 245.0
PYH2_k127_2109847_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
PYH2_k127_2109847_12 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000001518 234.0
PYH2_k127_2109847_13 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000000000102 192.0
PYH2_k127_2109847_14 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000925 188.0
PYH2_k127_2109847_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 601.0
PYH2_k127_2109847_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 494.0
PYH2_k127_2109847_4 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 439.0
PYH2_k127_2109847_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 432.0
PYH2_k127_2109847_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 350.0
PYH2_k127_2109847_7 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 327.0
PYH2_k127_2109847_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 310.0
PYH2_k127_2109847_9 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008261 269.0
PYH2_k127_2149277_0 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 466.0
PYH2_k127_2149277_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 376.0
PYH2_k127_2149277_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 355.0
PYH2_k127_2149277_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001083 265.0
PYH2_k127_2149277_4 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000001374 122.0
PYH2_k127_2149277_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000002375 108.0
PYH2_k127_2149277_6 - - - - 0.000000000000000000000001154 106.0
PYH2_k127_2149277_7 Large extracellular alpha-helical protein - - - 0.0000000002498 74.0
PYH2_k127_2156402_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 4.48e-209 673.0
PYH2_k127_2156402_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
PYH2_k127_2156402_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000001947 186.0
PYH2_k127_2156402_3 AAA domain K02282 - - 0.0000000000000000000000000000000000000000003998 172.0
PYH2_k127_2156402_5 amine dehydrogenase activity - - - 0.0000000000000002119 94.0
PYH2_k127_2156402_6 terpene metabolic process K16218 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0009987,GO:0010333,GO:0016829,GO:0016835,GO:0016838,GO:0042214,GO:0044237,GO:0044238,GO:0044255,GO:0071704 4.2.3.118 0.0007876 47.0
PYH2_k127_2169258_0 Psort location CytoplasmicMembrane, score K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000001016 171.0
PYH2_k127_2169258_1 beta-galactosidase activity - - - 0.0005388 52.0
PYH2_k127_2179263_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1058.0
PYH2_k127_2179263_1 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 555.0
PYH2_k127_2179263_10 GtrA-like protein - - - 0.00000000000000000000002322 106.0
PYH2_k127_2179263_11 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000001209 81.0
PYH2_k127_2179263_12 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000001646 71.0
PYH2_k127_2179263_2 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 513.0
PYH2_k127_2179263_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 331.0
PYH2_k127_2179263_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002023 270.0
PYH2_k127_2179263_5 PFAM O-antigen polymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003187 256.0
PYH2_k127_2179263_6 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000904 201.0
PYH2_k127_2179263_7 Baseplate J-like protein K01218 - 3.2.1.78 0.00000000000000000000000000000000000001374 166.0
PYH2_k127_2179263_8 GtrA-like protein - - - 0.000000000000000000000000000000001765 136.0
PYH2_k127_2179263_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000002777 117.0
PYH2_k127_218847_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 415.0
PYH2_k127_218847_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000459 149.0
PYH2_k127_218847_2 GIY-YIG catalytic domain protein K07461 - - 0.000000000000000000000005104 103.0
PYH2_k127_218847_3 Histidine kinase - - - 0.00000000000000000006548 91.0
PYH2_k127_218847_4 mRNA catabolic process - - - 0.000000000002212 78.0
PYH2_k127_2205367_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 442.0
PYH2_k127_2205367_1 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 282.0
PYH2_k127_2205367_2 Histidine phosphatase superfamily (branch 1) K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000001901 178.0
PYH2_k127_2205710_0 Glycosyl hydrolase family 66 K05988 - 3.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 313.0
PYH2_k127_2205710_1 ABC transporter (Permease) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 308.0
PYH2_k127_2205710_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 299.0
PYH2_k127_2205710_3 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004925 277.0
PYH2_k127_2205710_4 transmembrane transport K02025,K05814,K10109,K10118,K15771,K17242,K17245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001046 256.0
PYH2_k127_2254740_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.722e-208 663.0
PYH2_k127_2254740_1 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 553.0
PYH2_k127_2254740_10 Domain of unknown function (DUF4340) - - - 0.00000005281 63.0
PYH2_k127_2254740_11 Protein of unknown function (DUF2283) - - - 0.000000566 54.0
PYH2_k127_2254740_12 - - - - 0.000003126 53.0
PYH2_k127_2254740_13 - - - - 0.000174 53.0
PYH2_k127_2254740_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 498.0
PYH2_k127_2254740_3 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 411.0
PYH2_k127_2254740_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 376.0
PYH2_k127_2254740_5 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 364.0
PYH2_k127_2254740_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006251 271.0
PYH2_k127_2254740_7 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001312 273.0
PYH2_k127_2254740_8 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000001408 177.0
PYH2_k127_2254740_9 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000001787 87.0
PYH2_k127_2268705_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 350.0
PYH2_k127_2268705_1 PIN domain - - - 0.00000000000000002706 86.0
PYH2_k127_2287529_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1100.0
PYH2_k127_2287529_1 competence protein COMEC K02238 - - 5.036e-194 625.0
PYH2_k127_2287529_10 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000001615 175.0
PYH2_k127_2287529_11 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000001005 154.0
PYH2_k127_2287529_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000293 162.0
PYH2_k127_2287529_13 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000615 142.0
PYH2_k127_2287529_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000006165 150.0
PYH2_k127_2287529_15 chain length determinant protein - - - 0.00000000000000474 87.0
PYH2_k127_2287529_16 nucleotidyltransferase activity - - - 0.00003049 54.0
PYH2_k127_2287529_17 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00006142 47.0
PYH2_k127_2287529_2 PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 540.0
PYH2_k127_2287529_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 447.0
PYH2_k127_2287529_4 PFAM NAD dependent epimerase dehydratase family K01784,K08678 - 4.1.1.35,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 390.0
PYH2_k127_2287529_5 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 349.0
PYH2_k127_2287529_6 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004658 281.0
PYH2_k127_2287529_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000435 264.0
PYH2_k127_2287529_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 247.0
PYH2_k127_2287529_9 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000005599 193.0
PYH2_k127_2295410_0 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 504.0
PYH2_k127_2295410_1 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 459.0
PYH2_k127_2295410_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 474.0
PYH2_k127_2295410_3 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 371.0
PYH2_k127_2295410_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003166 242.0
PYH2_k127_2295410_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000006322 247.0
PYH2_k127_2295410_6 - - - - 0.0000000000004529 75.0
PYH2_k127_2295410_7 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000009615 68.0
PYH2_k127_2322040_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 329.0
PYH2_k127_2322040_1 - - - - 0.00000000000000237 78.0
PYH2_k127_2322040_2 - - - - 0.0000001081 59.0
PYH2_k127_2328935_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 464.0
PYH2_k127_2328935_1 PFAM BMC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 314.0
PYH2_k127_2328935_10 BMC K04027 - - 0.0000000000000000000000000000000000000777 143.0
PYH2_k127_2328935_11 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000003326 109.0
PYH2_k127_2328935_12 BMC - - - 0.000000000000004312 79.0
PYH2_k127_2328935_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003972 268.0
PYH2_k127_2328935_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000005274 224.0
PYH2_k127_2328935_4 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000001636 234.0
PYH2_k127_2328935_5 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000008731 216.0
PYH2_k127_2328935_6 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000000000000000000000000002632 193.0
PYH2_k127_2328935_7 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000682 185.0
PYH2_k127_2328935_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000002274 157.0
PYH2_k127_2328935_9 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.000000000000000000000000000000000000003832 156.0
PYH2_k127_2330484_0 Glycosyltransferase like family 2 - - - 0.0 1064.0
PYH2_k127_2330484_1 ABC-type multidrug transport system ATPase and permease K06147 - - 1.925e-223 707.0
PYH2_k127_2330484_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 341.0
PYH2_k127_2330484_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000351 228.0
PYH2_k127_2330484_4 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000003184 169.0
PYH2_k127_2330484_5 Phosphotransferase enzyme family - - - 0.00004179 55.0
PYH2_k127_2331299_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000001278 194.0
PYH2_k127_2331299_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000001836 95.0
PYH2_k127_2351308_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.154e-212 674.0
PYH2_k127_2357846_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 545.0
PYH2_k127_2357846_1 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 298.0
PYH2_k127_2357846_2 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004285 272.0
PYH2_k127_2357846_3 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001517 265.0
PYH2_k127_2357846_4 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006033 261.0
PYH2_k127_2357846_5 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000001915 115.0
PYH2_k127_2357846_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000002419 68.0
PYH2_k127_2357846_7 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000002754 69.0
PYH2_k127_2357846_8 Regulatory protein, FmdB family - - - 0.000000003769 61.0
PYH2_k127_2383552_0 ABC transporter transmembrane region K06147 - - 3.19e-267 834.0
PYH2_k127_2383552_1 ABC transporter transmembrane region K06147 - - 1.337e-250 787.0
PYH2_k127_2383552_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 297.0
PYH2_k127_2383552_3 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.00000000000000000000000000000000000000000000000000004174 193.0
PYH2_k127_2383552_4 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000000000000000000000000009194 151.0
PYH2_k127_2383552_6 - - - - 0.000000000000001834 83.0
PYH2_k127_2383552_7 alpha-L-arabinofuranosidase - - - 0.000122 53.0
PYH2_k127_2410812_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 399.0
PYH2_k127_2410812_1 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 364.0
PYH2_k127_2410812_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 293.0
PYH2_k127_2410812_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002113 203.0
PYH2_k127_2410812_4 response regulator K07667 - - 0.0000000000000000000000000000000000000000000000000001349 206.0
PYH2_k127_2425316_0 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 349.0
PYH2_k127_2425316_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002986 287.0
PYH2_k127_2425316_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000008443 184.0
PYH2_k127_2425316_3 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000109 154.0
PYH2_k127_2425316_4 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000005622 55.0
PYH2_k127_2465410_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 418.0
PYH2_k127_2465410_1 SMART AAA ATPase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 349.0
PYH2_k127_2465410_3 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000001382 179.0
PYH2_k127_2465410_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000001518 105.0
PYH2_k127_2465410_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000001405 77.0
PYH2_k127_2490203_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 1.486e-289 908.0
PYH2_k127_2490203_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.133e-206 651.0
PYH2_k127_2490203_2 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 389.0
PYH2_k127_2490203_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 300.0
PYH2_k127_2490203_4 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000003754 187.0
PYH2_k127_2490203_5 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000001982 139.0
PYH2_k127_2490203_6 histone deacetylase - - - 0.000000000000000007208 85.0
PYH2_k127_2495564_0 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003366 265.0
PYH2_k127_2495564_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000005614 243.0
PYH2_k127_2495564_2 Protein of unknown function DUF86 - - - 0.000000000000002994 78.0
PYH2_k127_2498511_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 3.049e-249 782.0
PYH2_k127_2498511_1 radical SAM domain protein - - - 1.035e-232 727.0
PYH2_k127_2498511_10 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.000000000000000000000000000000000000106 146.0
PYH2_k127_2498511_11 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000004254 143.0
PYH2_k127_2498511_12 sequence-specific DNA binding - - - 0.00000000000000000000000000000000959 139.0
PYH2_k127_2498511_13 Phosphotransferase enzyme family K18844 - - 0.0000000000000000000000001516 108.0
PYH2_k127_2498511_15 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000005628 76.0
PYH2_k127_2498511_16 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000008603 70.0
PYH2_k127_2498511_17 peptidyl-tyrosine sulfation - - - 0.000003743 58.0
PYH2_k127_2498511_18 - - - - 0.0005513 51.0
PYH2_k127_2498511_2 Elongation factor Tu domain 2 K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 588.0
PYH2_k127_2498511_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 392.0
PYH2_k127_2498511_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 315.0
PYH2_k127_2498511_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005323 255.0
PYH2_k127_2498511_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002566 240.0
PYH2_k127_2498511_7 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001458 232.0
PYH2_k127_2498511_8 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000000000000002297 154.0
PYH2_k127_2498511_9 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001711 148.0
PYH2_k127_2500057_0 Belongs to the peptidase S8 family - - - 1.794e-224 731.0
PYH2_k127_2500057_1 TIGRFAM MazG family protein K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 467.0
PYH2_k127_2500057_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000003122 226.0
PYH2_k127_2500057_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001171 226.0
PYH2_k127_2500057_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000003592 205.0
PYH2_k127_2500057_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002486 202.0
PYH2_k127_2500057_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002686 199.0
PYH2_k127_2500057_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001554 196.0
PYH2_k127_2500057_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003427 192.0
PYH2_k127_2500057_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000008899 171.0
PYH2_k127_2500057_18 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000002391 167.0
PYH2_k127_2500057_19 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000003646 161.0
PYH2_k127_2500057_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 429.0
PYH2_k127_2500057_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000371 154.0
PYH2_k127_2500057_21 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000001464 151.0
PYH2_k127_2500057_22 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001251 132.0
PYH2_k127_2500057_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000008355 119.0
PYH2_k127_2500057_24 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000009426 112.0
PYH2_k127_2500057_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000007785 104.0
PYH2_k127_2500057_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000001154 106.0
PYH2_k127_2500057_27 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002364 91.0
PYH2_k127_2500057_28 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002943 76.0
PYH2_k127_2500057_29 ATP-dependent transcriptional regulator K03556 - - 0.00000000005993 64.0
PYH2_k127_2500057_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 399.0
PYH2_k127_2500057_30 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000006757 65.0
PYH2_k127_2500057_31 structural constituent of ribosome - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000000001709 61.0
PYH2_k127_2500057_32 Bacterial SH3 domain - - - 0.00000005374 61.0
PYH2_k127_2500057_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 310.0
PYH2_k127_2500057_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007905 264.0
PYH2_k127_2500057_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009933 259.0
PYH2_k127_2500057_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH2_k127_2500057_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000009175 244.0
PYH2_k127_2500057_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000002946 228.0
PYH2_k127_2522646_0 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 619.0
PYH2_k127_2522646_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 343.0
PYH2_k127_2522646_2 Product type r regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004293 263.0
PYH2_k127_2522646_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002062 213.0
PYH2_k127_2522646_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000001588 127.0
PYH2_k127_2522646_5 SMART Parallel beta-helix repeat - - - 0.00000000000000000009441 105.0
PYH2_k127_2522646_6 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.00000000000006029 77.0
PYH2_k127_2522646_7 Cysteine-rich secretory protein family - - - 0.00000008399 66.0
PYH2_k127_2522646_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000008943 55.0
PYH2_k127_2531910_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 546.0
PYH2_k127_2531910_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 380.0
PYH2_k127_2531910_10 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000158 114.0
PYH2_k127_2531910_11 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000806 95.0
PYH2_k127_2531910_12 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001319 82.0
PYH2_k127_2531910_14 Domain of unknown function DUF11 - - - 0.0000005288 60.0
PYH2_k127_2531910_2 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000393 286.0
PYH2_k127_2531910_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000007786 244.0
PYH2_k127_2531910_4 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.00000000000000000000000000000000000000000000000000000000001682 213.0
PYH2_k127_2531910_5 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000002595 184.0
PYH2_k127_2531910_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000001762 178.0
PYH2_k127_2531910_7 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000001438 144.0
PYH2_k127_2531910_8 GTP binding - - - 0.0000000000000000000000000000000008864 135.0
PYH2_k127_2531910_9 transposase activity - - - 0.000000000000000000000000000002244 122.0
PYH2_k127_2539023_0 PFAM Cys Met metabolism K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 475.0
PYH2_k127_2539023_1 Double zinc ribbon - - - 0.0000000000000000000000000000000000000000000000000000000000007662 218.0
PYH2_k127_2539023_2 - - - - 0.00000000000000000007487 98.0
PYH2_k127_2539023_3 protein homolog of Cu resistance protein CopC K07156 - - 0.000000000000001863 82.0
PYH2_k127_2539923_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.812e-302 963.0
PYH2_k127_2539923_1 BON domain - - - 0.00000005925 64.0
PYH2_k127_2539923_2 - - - - 0.00004337 55.0
PYH2_k127_2543269_0 CpXC protein - - - 4.463e-237 780.0
PYH2_k127_2543269_1 contains PIN domain - - - 0.0000000000000000000004279 103.0
PYH2_k127_2543269_2 PFAM Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000004842 90.0
PYH2_k127_255032_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 374.0
PYH2_k127_255032_1 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000007073 226.0
PYH2_k127_255032_2 Transposase K07494 - - 0.0000000000000000000000000000000001312 135.0
PYH2_k127_2639737_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 602.0
PYH2_k127_2639737_1 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 481.0
PYH2_k127_2639737_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 371.0
PYH2_k127_2639737_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 319.0
PYH2_k127_2639737_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001672 241.0
PYH2_k127_2639737_5 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.000000000000000000000000000000000000000000000000000006408 196.0
PYH2_k127_2639737_6 Protein of unknown function (DUF1706) - - - 0.000000000000000000006892 99.0
PYH2_k127_2639737_7 - - - - 0.00001355 48.0
PYH2_k127_2646937_0 Ethyl tert-butyl ether degradation - - - 0.000000000000000000000000000000001001 133.0
PYH2_k127_2646937_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000002511 99.0
PYH2_k127_2646937_2 Sh3 type 3 domain protein K01256,K01361 - 3.4.11.2,3.4.21.96 0.000008487 59.0
PYH2_k127_2661148_0 Penicillin amidase K01434 - 3.5.1.11 3.542e-217 702.0
PYH2_k127_2661148_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 632.0
PYH2_k127_2661148_11 Pectate lyase K01728 - 4.2.2.2 0.0007192 51.0
PYH2_k127_2661148_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 396.0
PYH2_k127_2661148_3 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 332.0
PYH2_k127_2661148_4 Domain present in PSD-95, Dlg, and ZO-1/2. K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 304.0
PYH2_k127_2661148_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000116 264.0
PYH2_k127_2661148_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000004853 232.0
PYH2_k127_2661148_7 Peptidoglycan-binding lysin domain - - - 0.00000000000000004933 94.0
PYH2_k127_2661148_8 chitin deacetylase K22278 - 3.5.1.104 0.00000002417 65.0
PYH2_k127_2661148_9 Belongs to the peptidase S8 family K01361,K08652 - 3.4.21.110,3.4.21.96 0.0001524 53.0
PYH2_k127_2708972_0 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 428.0
PYH2_k127_2749972_0 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 370.0
PYH2_k127_2749972_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 329.0
PYH2_k127_2749972_2 Histidine phosphatase superfamily (branch 1) K01834 - 5.4.2.11 0.0000000000000000000000000002969 117.0
PYH2_k127_2772422_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 526.0
PYH2_k127_2772422_1 TIGRFAM dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 315.0
PYH2_k127_2772422_2 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 295.0
PYH2_k127_2806722_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.299e-264 822.0
PYH2_k127_2806722_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 5.465e-251 785.0
PYH2_k127_2806722_10 HEPN domain - - - 0.0000000000000000006438 91.0
PYH2_k127_2806722_11 YacP-like NYN domain K06962 - - 0.00000000002165 66.0
PYH2_k127_2806722_12 PFAM coagulation factor 5 8 type domain protein - - - 0.00009746 55.0
PYH2_k127_2806722_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 2.673e-207 682.0
PYH2_k127_2806722_3 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 565.0
PYH2_k127_2806722_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 313.0
PYH2_k127_2806722_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 312.0
PYH2_k127_2806722_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000008723 173.0
PYH2_k127_2806722_7 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000000000000000000003774 133.0
PYH2_k127_2806722_8 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000000003443 130.0
PYH2_k127_2806722_9 nucleotidyltransferase activity K07076 - - 0.0000000000000000000000007207 108.0
PYH2_k127_2816638_0 PFAM extracellular solute-binding protein family 1 K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 563.0
PYH2_k127_2816638_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 445.0
PYH2_k127_2816638_10 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.000000000000000000000000000000000000149 152.0
PYH2_k127_2816638_11 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000109 120.0
PYH2_k127_2816638_2 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 421.0
PYH2_k127_2816638_3 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 387.0
PYH2_k127_2816638_4 PFAM major facilitator superfamily MFS_1 K08162 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 388.0
PYH2_k127_2816638_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
PYH2_k127_2816638_6 ABC-3 protein K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
PYH2_k127_2816638_7 Zinc-uptake complex component A periplasmic K02077,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004511 265.0
PYH2_k127_2816638_8 PFAM ABC transporter related K09820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
PYH2_k127_2816638_9 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002408 254.0
PYH2_k127_2817022_0 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 420.0
PYH2_k127_2817022_1 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000001899 198.0
PYH2_k127_2817022_2 COG4313 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000009412 129.0
PYH2_k127_2819112_0 Glycosyl hydrolase family 53 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001366 249.0
PYH2_k127_2819112_1 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.0000000000000000000000000000000000007513 151.0
PYH2_k127_2819112_2 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.000000000001076 81.0
PYH2_k127_2830222_0 family 4 K01222 - 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 349.0
PYH2_k127_2830222_1 Carbohydrate kinase - - - 0.000000000000000015 85.0
PYH2_k127_2841556_0 pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 6.387e-215 695.0
PYH2_k127_2841556_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 574.0
PYH2_k127_2841556_2 - - - - 0.0000000000000000387 84.0
PYH2_k127_2850429_0 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000002515 220.0
PYH2_k127_2850429_1 PFAM VanW family protein - - - 0.00000000000000000000000000000000000000000000001198 185.0
PYH2_k127_2850429_2 Activator of Hsp90 ATPase - - - 0.00000001038 62.0
PYH2_k127_2857726_0 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000009066 186.0
PYH2_k127_2857726_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000001421 117.0
PYH2_k127_2865765_0 PhoQ Sensor - - - 1.9e-207 661.0
PYH2_k127_2872049_0 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 543.0
PYH2_k127_2872049_1 - - - - 0.000778 46.0
PYH2_k127_2885292_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000002226 238.0
PYH2_k127_2890722_0 Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000001669 134.0
PYH2_k127_2890722_1 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000001965 128.0
PYH2_k127_2890722_2 - - - - 0.00000000000000008393 90.0
PYH2_k127_2890722_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000001096 68.0
PYH2_k127_2900363_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 563.0
PYH2_k127_2900363_1 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000003071 144.0
PYH2_k127_2916277_0 PFAM O-antigen polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 391.0
PYH2_k127_2916277_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 330.0
PYH2_k127_2916277_10 - - - - 0.0000000005356 73.0
PYH2_k127_2916277_11 STAS domain - - - 0.00000005765 59.0
PYH2_k127_2916277_2 - - - - 0.00000000000000000000000000000000000000000000000000000000002124 229.0
PYH2_k127_2916277_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000002792 165.0
PYH2_k127_2916277_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001178 151.0
PYH2_k127_2916277_5 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000000000000000004427 130.0
PYH2_k127_2916277_6 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000003073 88.0
PYH2_k127_2916277_7 - - - - 0.000000000000002268 91.0
PYH2_k127_2916277_8 Bacterial membrane protein, YfhO - - - 0.000000000000004011 85.0
PYH2_k127_2916277_9 Psort location CytoplasmicMembrane, score - - - 0.0000000000001781 85.0
PYH2_k127_2929160_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.885e-206 659.0
PYH2_k127_2929160_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 561.0
PYH2_k127_2929160_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 532.0
PYH2_k127_2929160_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 437.0
PYH2_k127_2929160_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 391.0
PYH2_k127_2929160_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 369.0
PYH2_k127_2929160_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 342.0
PYH2_k127_2929160_7 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 306.0
PYH2_k127_2929160_8 ABC transporter substrate-binding protein PnrA-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 298.0
PYH2_k127_2929160_9 Deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001917 265.0
PYH2_k127_2964408_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 3.268e-231 728.0
PYH2_k127_2964408_1 PFAM Nickel-dependent hydrogenase, large subunit - - - 6.404e-194 618.0
PYH2_k127_2964408_10 4Fe-4S binding domain K14091 - - 0.000000000000000000000000000000000000000000000000000005392 198.0
PYH2_k127_2964408_11 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000000001298 194.0
PYH2_k127_2964408_12 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000002101 172.0
PYH2_k127_2964408_13 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000002428 167.0
PYH2_k127_2964408_14 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000007006 148.0
PYH2_k127_2964408_16 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000008119 143.0
PYH2_k127_2964408_17 phosphorelay signal transduction system - - - 0.0000000000000000000000000000005474 126.0
PYH2_k127_2964408_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332,K13378 - 1.6.5.3 0.00000000000000000000000006192 121.0
PYH2_k127_2964408_19 hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000008817 98.0
PYH2_k127_2964408_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 607.0
PYH2_k127_2964408_21 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000001983 96.0
PYH2_k127_2964408_22 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.000000000000000003776 89.0
PYH2_k127_2964408_3 ATP synthesis coupled electron transport K00342,K00343,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 529.0
PYH2_k127_2964408_4 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 416.0
PYH2_k127_2964408_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 390.0
PYH2_k127_2964408_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 387.0
PYH2_k127_2964408_7 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 342.0
PYH2_k127_2964408_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000168 265.0
PYH2_k127_2964408_9 PFAM glutamine amidotransferase class-I K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000002759 231.0
PYH2_k127_3002844_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 1.838e-230 741.0
PYH2_k127_3002844_1 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0005006 48.0
PYH2_k127_3003916_0 Major facilitator Superfamily K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 457.0
PYH2_k127_3003916_1 PFAM Periplasmic binding protein LacI transcriptional regulator K02529,K03604 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001216,GO:0001217,GO:0002054,GO:0002057,GO:0002060,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006140,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019220,GO:0019222,GO:0030808,GO:0030809,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0036094,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045980,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 314.0
PYH2_k127_3003916_10 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000001347 104.0
PYH2_k127_3003916_11 - - - - 0.0000000000000000000005589 109.0
PYH2_k127_3003916_12 - - - - 0.00000000000000000001713 95.0
PYH2_k127_3003916_14 - - - - 0.00000156 61.0
PYH2_k127_3003916_2 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000006569 193.0
PYH2_k127_3003916_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000006945 152.0
PYH2_k127_3003916_4 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00917 - 2.7.1.144 0.000000000000000000000000000000000001313 151.0
PYH2_k127_3003916_5 - - - - 0.00000000000000000000000000000002607 131.0
PYH2_k127_3003916_6 oxalate decarboxylase activity K06859 - 5.3.1.9 0.000000000000000000000000000004346 129.0
PYH2_k127_3003916_7 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000005512 117.0
PYH2_k127_3003916_8 Class ii aldolase K01628,K01629,K03077 - 4.1.2.17,4.1.2.19,5.1.3.4 0.0000000000000000000000000189 116.0
PYH2_k127_3003916_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000003239 123.0
PYH2_k127_3013427_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.172e-202 636.0
PYH2_k127_3013427_1 - - - - 1.864e-195 617.0
PYH2_k127_3013427_10 Protein conserved in bacteria - - - 0.0000000002698 65.0
PYH2_k127_3013427_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 404.0
PYH2_k127_3013427_3 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 334.0
PYH2_k127_3013427_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 329.0
PYH2_k127_3013427_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 301.0
PYH2_k127_3013427_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000003038 198.0
PYH2_k127_3013427_7 lipid binding - - - 0.0000000000000000000000000000000000000000000000000303 189.0
PYH2_k127_3013427_8 TIGRFAM phosphoesterase, MJ0936 family - - - 0.00000000000000000000000000000000000000005621 162.0
PYH2_k127_3016405_0 PFAM type II secretion system protein E K02283 - - 1.078e-203 644.0
PYH2_k127_3016405_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 338.0
PYH2_k127_3016405_2 PFAM type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
PYH2_k127_3016405_3 PFAM type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005169 274.0
PYH2_k127_3016405_4 phosphoribosyltransferase - - - 0.0001409 46.0
PYH2_k127_3035131_0 helix_turn_helix, Lux Regulon K03556 - - 1.371e-201 658.0
PYH2_k127_3035131_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 360.0
PYH2_k127_3035131_10 SMART Nucleotide binding protein, PINc K07063 - - 0.0002677 46.0
PYH2_k127_3035131_2 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000001251 193.0
PYH2_k127_3035131_3 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000001685 167.0
PYH2_k127_3035131_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000002519 133.0
PYH2_k127_3035131_5 Transport permease protein K01992 - - 0.000000000000000000000000000001231 138.0
PYH2_k127_3035131_6 - - - - 0.000000000000000000000006548 109.0
PYH2_k127_3035131_7 - - - - 0.0000000000003125 73.0
PYH2_k127_3035131_8 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000008918 61.0
PYH2_k127_3035131_9 Alpha/beta hydrolase family - - - 0.00000008406 56.0
PYH2_k127_3036422_0 - - - - 0.0000000000000000000000000000000004021 135.0
PYH2_k127_3036422_1 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000000001675 93.0
PYH2_k127_3036422_2 STAS domain - - - 0.00000000000000851 79.0
PYH2_k127_3036422_3 iron ion binding - - - 0.0000000000001547 70.0
PYH2_k127_3036422_4 Bacterial transcriptional activator domain - - - 0.0000008214 53.0
PYH2_k127_3094209_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 496.0
PYH2_k127_3094209_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 468.0
PYH2_k127_3094209_2 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 325.0
PYH2_k127_3094209_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000018 291.0
PYH2_k127_3094209_4 phosphatase (DUF442) - - - 0.0000000000000000000000000000000000000000000008827 169.0
PYH2_k127_3094209_5 DinB family - - - 0.0000000000000000000000000000000000003086 144.0
PYH2_k127_3094209_6 Dodecin K09165 - - 0.00000000000000000000000003667 108.0
PYH2_k127_3094209_7 - - - - 0.000000000001579 78.0
PYH2_k127_3094209_8 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.000134 47.0
PYH2_k127_3107325_0 cellulase activity K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 365.0
PYH2_k127_3107325_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004998 282.0
PYH2_k127_3107325_2 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000005422 126.0
PYH2_k127_3107325_3 Endonuclease Exonuclease Phosphatase K07004 - - 0.00002237 58.0
PYH2_k127_3110509_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 289.0
PYH2_k127_3120491_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 424.0
PYH2_k127_3120491_1 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 294.0
PYH2_k127_3120491_2 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001054 281.0
PYH2_k127_3120491_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005858 273.0
PYH2_k127_3120491_4 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000001933 237.0
PYH2_k127_3120491_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000002265 203.0
PYH2_k127_3120491_6 Response regulator, receiver - - - 0.0000000000000000000000008135 115.0
PYH2_k127_3120491_7 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000000000006961 97.0
PYH2_k127_3120491_8 - - - - 0.0000000000000003845 86.0
PYH2_k127_3120491_9 - - - - 0.0000000000001909 80.0
PYH2_k127_3134023_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 5.011e-299 931.0
PYH2_k127_3134023_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 331.0
PYH2_k127_3134023_2 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000005566 108.0
PYH2_k127_3134023_3 - - - - 0.000000000000000000000003498 106.0
PYH2_k127_3134023_5 Protein of unknown function (DUF998) - - - 0.0000002608 61.0
PYH2_k127_3137402_0 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001892 285.0
PYH2_k127_3137402_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000002219 72.0
PYH2_k127_3137402_2 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000002078 71.0
PYH2_k127_3137402_3 Transposase (IS116 IS110 IS902 family) - - - 0.00002449 54.0
PYH2_k127_3142499_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 336.0
PYH2_k127_3142499_1 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000004817 216.0
PYH2_k127_3148893_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.197e-216 682.0
PYH2_k127_3148893_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002359 247.0
PYH2_k127_3148893_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001478 200.0
PYH2_k127_3148893_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000003387 113.0
PYH2_k127_3151761_0 PFAM ABC-1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 389.0
PYH2_k127_3151761_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000002165 263.0
PYH2_k127_3151761_10 Ig-like domain from next to BRCA1 gene K17987 - - 0.000000001562 72.0
PYH2_k127_3151761_11 chitin binding - - - 0.000000006194 70.0
PYH2_k127_3151761_12 Glyco_18 - - - 0.000001932 62.0
PYH2_k127_3151761_2 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000008028 265.0
PYH2_k127_3151761_3 regulation of circadian rhythm K08482 - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
PYH2_k127_3151761_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000683 178.0
PYH2_k127_3151761_5 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000001183 132.0
PYH2_k127_3151761_7 Ig-like domain from next to BRCA1 gene - - - 0.00000000000001396 89.0
PYH2_k127_3151761_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000005188 74.0
PYH2_k127_3160290_0 FAD dependent oxidoreductase - - - 5.762e-208 660.0
PYH2_k127_3160290_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 441.0
PYH2_k127_3160290_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000002382 192.0
PYH2_k127_3160290_3 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000005361 154.0
PYH2_k127_3160290_4 NB-ARC domain - - - 0.0000002008 63.0
PYH2_k127_3163180_0 Heat shock 70 kDa protein K04043 - - 1.68e-271 847.0
PYH2_k127_3163180_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 615.0
PYH2_k127_3163180_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 336.0
PYH2_k127_3163180_3 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000005778 222.0
PYH2_k127_3163180_4 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000006332 207.0
PYH2_k127_3163180_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000002949 148.0
PYH2_k127_3163180_6 Belongs to the Fur family K03711 - - 0.000000000000000000003748 102.0
PYH2_k127_3163180_7 FeoA K04758 - - 0.000000005478 61.0
PYH2_k127_3184809_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 325.0
PYH2_k127_3184809_1 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 310.0
PYH2_k127_3184809_2 PFAM Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000008619 246.0
PYH2_k127_3184809_3 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000481 135.0
PYH2_k127_3189509_0 ABC transporter K06147 - - 1.141e-235 747.0
PYH2_k127_3189509_1 DUF3160 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 413.0
PYH2_k127_3189509_10 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.000000000000000000000000000000000000001316 156.0
PYH2_k127_3189509_11 DinB family - - - 0.0000000000000000000000000000006304 136.0
PYH2_k127_3189509_12 thiolester hydrolase activity K01181,K06889 - 3.2.1.8 0.00000000000000000000000007768 112.0
PYH2_k127_3189509_13 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.00000000000000000000003179 109.0
PYH2_k127_3189509_14 Protein of unknown function (DUF1572) - - - 0.0000000000000000000006825 100.0
PYH2_k127_3189509_15 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.000000000000000000001076 104.0
PYH2_k127_3189509_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000002401 90.0
PYH2_k127_3189509_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 312.0
PYH2_k127_3189509_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 291.0
PYH2_k127_3189509_4 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001409 288.0
PYH2_k127_3189509_5 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003168 257.0
PYH2_k127_3189509_6 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
PYH2_k127_3189509_7 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000006334 244.0
PYH2_k127_3189509_8 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000006566 245.0
PYH2_k127_3189509_9 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000001377 184.0
PYH2_k127_3202450_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 481.0
PYH2_k127_3211282_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002482 245.0
PYH2_k127_3211282_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000004027 231.0
PYH2_k127_3211282_2 FAD linked K00803 - 2.5.1.26 0.0000000005485 61.0
PYH2_k127_3220095_0 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007263 597.0
PYH2_k127_3220095_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 346.0
PYH2_k127_3220095_2 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000004836 207.0
PYH2_k127_3220095_3 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000006536 202.0
PYH2_k127_3220095_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000006718 111.0
PYH2_k127_3220095_5 ethanolamine kinase activity K07251,K18844 - 2.7.1.89 0.00000000000000000001306 104.0
PYH2_k127_3220095_6 Response regulator receiver domain K11443 - - 0.0000000000001087 77.0
PYH2_k127_3220095_7 peptidase - - - 0.00000000000135 80.0
PYH2_k127_3223051_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000001904 264.0
PYH2_k127_3223051_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006798 263.0
PYH2_k127_3223051_2 - - - - 0.00003313 52.0
PYH2_k127_3228191_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 456.0
PYH2_k127_3228191_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 362.0
PYH2_k127_3228191_2 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
PYH2_k127_3228191_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000007236 159.0
PYH2_k127_3228191_4 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000000000000000000000002463 115.0
PYH2_k127_3231267_0 PFAM fumarate lyase K01679 - 4.2.1.2 8.972e-202 642.0
PYH2_k127_3231267_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 304.0
PYH2_k127_3231267_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000002393 175.0
PYH2_k127_3231267_3 DNA methylase K07316 - 2.1.1.72 0.000001625 53.0
PYH2_k127_3293927_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
PYH2_k127_3293927_1 HD domain K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000197 229.0
PYH2_k127_3293927_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000003174 197.0
PYH2_k127_3293927_3 PFAM major facilitator superfamily MFS_1 K06902 - - 0.0000000000000000003362 88.0
PYH2_k127_3336447_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 360.0
PYH2_k127_3336447_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 297.0
PYH2_k127_3336447_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000007801 175.0
PYH2_k127_3336447_3 cytochrome K08738 - - 0.00000000003654 73.0
PYH2_k127_3341876_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 621.0
PYH2_k127_3341876_1 PHP domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 531.0
PYH2_k127_3341876_10 hydrolase K19224,K21471 - - 0.000579 49.0
PYH2_k127_3341876_2 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 455.0
PYH2_k127_3341876_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 411.0
PYH2_k127_3341876_4 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 359.0
PYH2_k127_3341876_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000006285 266.0
PYH2_k127_3341876_6 Bacterial SH3 domain - - - 0.000000000000000001373 93.0
PYH2_k127_3341876_7 NUDIX domain - - - 0.00000000001248 69.0
PYH2_k127_3341876_8 Pro-kumamolisin, activation domain - - - 0.00000005561 67.0
PYH2_k127_3341876_9 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.00007828 46.0
PYH2_k127_3349205_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000954 273.0
PYH2_k127_3349205_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000004327 218.0
PYH2_k127_3349205_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000001107 229.0
PYH2_k127_3402561_0 nitrite transmembrane transporter activity K02532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 593.0
PYH2_k127_3402561_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 554.0
PYH2_k127_3402561_2 metallopeptidase activity K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 503.0
PYH2_k127_3402561_3 PFAM O-methyltransferase, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000009944 228.0
PYH2_k127_3402561_4 Sh3 type 3 domain protein K01448,K07448 - 3.5.1.28 0.0000000000000000001064 104.0
PYH2_k127_3402561_5 Copper resistance protein CopC K14166 - - 0.000000000001611 74.0
PYH2_k127_3402561_6 Peptidase, M23 family K21471 - - 0.00000007804 65.0
PYH2_k127_3410871_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1191.0
PYH2_k127_3410871_1 Dual specificity phosphatase, catalytic domain - - - 2.436e-260 824.0
PYH2_k127_3410871_10 DinB family - - - 0.00000000000007088 79.0
PYH2_k127_3410871_11 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00007494 46.0
PYH2_k127_3410871_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 476.0
PYH2_k127_3410871_3 PFAM deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 293.0
PYH2_k127_3410871_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 289.0
PYH2_k127_3410871_5 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002101 264.0
PYH2_k127_3410871_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001362 267.0
PYH2_k127_3410871_7 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001419 258.0
PYH2_k127_3410871_8 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000002469 147.0
PYH2_k127_3410871_9 DUF218 domain - - - 0.000000000000000000000000000000009569 135.0
PYH2_k127_3421039_0 HemN C-terminal domain - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
PYH2_k127_3421039_1 Protein of unknown function (DUF1566) - - - 0.0000000000000003693 93.0
PYH2_k127_342235_0 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 518.0
PYH2_k127_3506121_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 468.0
PYH2_k127_3506121_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 340.0
PYH2_k127_3506121_10 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000004891 118.0
PYH2_k127_3506121_11 PFAM cyclic nucleotide-binding - - - 0.0000000000000000000000002923 111.0
PYH2_k127_3506121_12 Tetratricopeptide repeat - - - 0.000000000000000000001244 108.0
PYH2_k127_3506121_13 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000002219 91.0
PYH2_k127_3506121_14 Cyclic-di-AMP receptor - - - 0.000000000000000009738 87.0
PYH2_k127_3506121_15 PFAM Forkhead-associated protein - - - 0.00000000000004117 79.0
PYH2_k127_3506121_16 - - - - 0.0005426 49.0
PYH2_k127_3506121_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 304.0
PYH2_k127_3506121_3 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 297.0
PYH2_k127_3506121_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000006672 253.0
PYH2_k127_3506121_5 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000001334 246.0
PYH2_k127_3506121_6 glycosyl transferase group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000002853 243.0
PYH2_k127_3506121_7 Kelch repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000002113 235.0
PYH2_k127_3506121_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000009626 171.0
PYH2_k127_3506121_9 phosphatase activity K07025,K08723,K20862 - 3.1.3.102,3.1.3.104,3.1.3.5 0.000000000000000000000000000000008874 136.0
PYH2_k127_359012_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1300.0
PYH2_k127_359012_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 1.907e-196 619.0
PYH2_k127_359012_2 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 419.0
PYH2_k127_359012_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 369.0
PYH2_k127_359012_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 310.0
PYH2_k127_359012_5 - - - - 0.0000000000005257 75.0
PYH2_k127_359040_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.239e-256 851.0
PYH2_k127_359040_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 365.0
PYH2_k127_359040_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 312.0
PYH2_k127_359040_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000001395 134.0
PYH2_k127_359040_4 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K01126,K10716 - 3.1.4.46 0.0001677 48.0
PYH2_k127_3600047_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 5.54e-214 687.0
PYH2_k127_3600047_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 370.0
PYH2_k127_3600047_10 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000005593 55.0
PYH2_k127_3600047_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 301.0
PYH2_k127_3600047_3 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000009273 208.0
PYH2_k127_3600047_4 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000107 158.0
PYH2_k127_3600047_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000001608 145.0
PYH2_k127_3600047_6 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000006069 144.0
PYH2_k127_3600047_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000004735 141.0
PYH2_k127_3600047_8 - - - - 0.00000000000000000000000000001716 123.0
PYH2_k127_3600047_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000005236 103.0
PYH2_k127_360075_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 481.0
PYH2_k127_360075_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 345.0
PYH2_k127_360075_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000003288 229.0
PYH2_k127_360075_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000002505 201.0
PYH2_k127_360075_4 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000001804 116.0
PYH2_k127_360075_5 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000005958 109.0
PYH2_k127_360075_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000001638 65.0
PYH2_k127_361424_0 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 406.0
PYH2_k127_361424_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 395.0
PYH2_k127_361424_10 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000157 136.0
PYH2_k127_361424_11 metal cluster binding K06940,K18475 - - 0.0000000000000000000000000004615 121.0
PYH2_k127_361424_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000325 109.0
PYH2_k127_361424_14 helix_turn_helix, Lux Regulon - - - 0.000000000004053 68.0
PYH2_k127_361424_15 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00007875 48.0
PYH2_k127_361424_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 384.0
PYH2_k127_361424_3 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 352.0
PYH2_k127_361424_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 344.0
PYH2_k127_361424_5 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 351.0
PYH2_k127_361424_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 332.0
PYH2_k127_361424_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 319.0
PYH2_k127_361424_8 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 287.0
PYH2_k127_361424_9 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008079 282.0
PYH2_k127_361559_0 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 393.0
PYH2_k127_361559_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 350.0
PYH2_k127_361559_2 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006623 265.0
PYH2_k127_361559_3 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000001294 199.0
PYH2_k127_361559_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000007214 150.0
PYH2_k127_361559_5 Flagellar filament outer layer protein Flaa - - - 0.000000000000000109 94.0
PYH2_k127_361559_6 PFAM cell divisionFtsK SpoIIIE K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0003521 45.0
PYH2_k127_362978_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 5.37e-218 687.0
PYH2_k127_362978_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 464.0
PYH2_k127_362978_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 454.0
PYH2_k127_362978_3 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 282.0
PYH2_k127_362978_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000124 177.0
PYH2_k127_362978_5 - - - - 0.000000000000000000000000000000000001255 139.0
PYH2_k127_362978_6 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000005214 132.0
PYH2_k127_362978_7 - - - - 0.000000000000000000000000144 109.0
PYH2_k127_362978_8 - - - - 0.0000000000000000000001591 111.0
PYH2_k127_362978_9 - - - - 0.00000000004587 73.0
PYH2_k127_36555_0 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
PYH2_k127_36555_1 Ferritin-like - - - 0.00000000000000000000000000000000000000000000002144 175.0
PYH2_k127_36555_2 META domain - - - 0.000006539 57.0
PYH2_k127_3671922_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000003705 88.0
PYH2_k127_3671922_1 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.000000000001709 81.0
PYH2_k127_3707052_0 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 424.0
PYH2_k127_3707052_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000005978 242.0
PYH2_k127_3707052_2 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000001675 229.0
PYH2_k127_3707052_3 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000312 138.0
PYH2_k127_371302_0 PFAM binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 417.0
PYH2_k127_371302_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 389.0
PYH2_k127_371302_2 DNA import into cell involved in transformation K02053,K11070 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 325.0
PYH2_k127_371302_3 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000215 196.0
PYH2_k127_3729071_0 hydrogenase large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 587.0
PYH2_k127_3729071_1 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000001256 205.0
PYH2_k127_3729071_2 SMART helix-turn-helix domain protein K18831 - - 0.00000000000000000000000000000000000000000000001224 175.0
PYH2_k127_3729071_3 Hydrogenase maturation protease K00442 - - 0.000000000000000000000000000000000000000009893 159.0
PYH2_k127_3729071_4 PFAM Phosphoribosyltransferase - - - 0.0004827 43.0
PYH2_k127_3773264_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.765e-204 661.0
PYH2_k127_3773264_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 571.0
PYH2_k127_3773264_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 308.0
PYH2_k127_3773264_3 DNA helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002362 259.0
PYH2_k127_3773264_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000003441 236.0
PYH2_k127_3773264_5 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000001114 220.0
PYH2_k127_3773264_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000005197 179.0
PYH2_k127_3773264_7 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000003784 181.0
PYH2_k127_3773264_8 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000003583 164.0
PYH2_k127_3773264_9 NYN domain - - - 0.000000000000003742 86.0
PYH2_k127_3779673_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
PYH2_k127_3779673_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K02381 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 422.0
PYH2_k127_3779673_10 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000004768 207.0
PYH2_k127_3779673_11 Eco57I restriction-modification methylase - - - 0.0000000000000000000000000000000000000005541 154.0
PYH2_k127_3779673_12 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000009676 148.0
PYH2_k127_3779673_13 Cytochrome c554 and c-prime - - - 0.000000000000000000000008835 117.0
PYH2_k127_3779673_15 Bacterial transcriptional activator domain - - - 0.000000000000003392 87.0
PYH2_k127_3779673_16 Protein of unknown function (DUF1116) - - - 0.0000000001279 63.0
PYH2_k127_3779673_17 PFAM ComEC Rec2-related protein K02238 - - 0.0000000001708 67.0
PYH2_k127_3779673_2 Membrane protein FdrA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 403.0
PYH2_k127_3779673_20 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0007843 43.0
PYH2_k127_3779673_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 370.0
PYH2_k127_3779673_4 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 323.0
PYH2_k127_3779673_5 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 288.0
PYH2_k127_3779673_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006336 282.0
PYH2_k127_3779673_7 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007745 295.0
PYH2_k127_3779673_9 PFAM Basic membrane lipoprotein K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000004809 250.0
PYH2_k127_3785933_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 585.0
PYH2_k127_3785933_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 403.0
PYH2_k127_3785933_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 377.0
PYH2_k127_3785933_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009716 246.0
PYH2_k127_3785933_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000002744 206.0
PYH2_k127_3785933_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000616 134.0
PYH2_k127_3785933_6 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000007071 112.0
PYH2_k127_3785933_7 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000003111 104.0
PYH2_k127_3785933_8 PFAM S4 domain K14761 - - 0.0000000000000000009148 87.0
PYH2_k127_3785933_9 membrane - - - 0.00000003268 63.0
PYH2_k127_3791330_0 Glycosyltransferase Family 4 - - - 0.0 1304.0
PYH2_k127_3791330_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 550.0
PYH2_k127_3791330_10 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000001066 100.0
PYH2_k127_3791330_11 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000178 90.0
PYH2_k127_3791330_12 Histidine kinase - - - 0.00000000000000002375 98.0
PYH2_k127_3791330_13 CarD-like/TRCF domain K07736 - - 0.000000000002735 73.0
PYH2_k127_3791330_14 Cation transporter/ATPase, N-terminus K01531,K01535 - 3.6.3.2,3.6.3.6 0.00000000006104 66.0
PYH2_k127_3791330_15 - - - - 0.0000000007034 70.0
PYH2_k127_3791330_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000007909 74.0
PYH2_k127_3791330_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 446.0
PYH2_k127_3791330_3 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 324.0
PYH2_k127_3791330_4 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 316.0
PYH2_k127_3791330_5 Bacterial regulatory proteins, crp family K01420 - - 0.00000000000000000000000000000000000000000000000000000003653 203.0
PYH2_k127_3791330_6 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000002914 205.0
PYH2_k127_3791330_7 integral membrane protein - - - 0.0000000000000000000000000000000000000000000003928 182.0
PYH2_k127_3791330_8 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000004071 164.0
PYH2_k127_3791330_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.00000000000000000000000000024 120.0
PYH2_k127_3794363_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 373.0
PYH2_k127_3794363_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000004457 156.0
PYH2_k127_3794363_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000001093 141.0
PYH2_k127_3794363_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000001416 138.0
PYH2_k127_3794363_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000007097 115.0
PYH2_k127_3794363_5 Antibiotic biosynthesis monooxygenase - - - 0.0000000000006201 74.0
PYH2_k127_3794363_6 PFAM Polyketide cyclase dehydrase - - - 0.000000000001469 74.0
PYH2_k127_3794363_7 GYD domain - - - 0.0000002052 55.0
PYH2_k127_3794363_8 smart pdz dhr glgf K04771 - 3.4.21.107 0.00004403 55.0
PYH2_k127_3802297_0 Belongs to the carbamoyltransferase HypF family K04656 - - 4.824e-214 683.0
PYH2_k127_3802297_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 609.0
PYH2_k127_3802297_10 sequence-specific DNA binding - - - 0.000000009988 59.0
PYH2_k127_3802297_2 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 608.0
PYH2_k127_3802297_3 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 546.0
PYH2_k127_3802297_4 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
PYH2_k127_3802297_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 303.0
PYH2_k127_3802297_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000008424 220.0
PYH2_k127_3802297_7 - - - - 0.00000000000000000000000000000000000000000000000000003694 197.0
PYH2_k127_3802297_8 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000001186 121.0
PYH2_k127_3802297_9 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000105 83.0
PYH2_k127_3810042_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.797e-213 677.0
PYH2_k127_3810042_1 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 605.0
PYH2_k127_3810042_10 serine-type aminopeptidase activity K14475 - - 0.00000000000000000000006641 114.0
PYH2_k127_3810042_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000003204 97.0
PYH2_k127_3810042_12 - - - - 0.0000000000000000003167 92.0
PYH2_k127_3810042_13 Glutaredoxin-like domain (DUF836) - - - 0.000000000002177 70.0
PYH2_k127_3810042_15 Esterase-like activity of phytase - - - 0.00001003 59.0
PYH2_k127_3810042_16 LAO AO transport system ATPase K07588 - - 0.0003507 45.0
PYH2_k127_3810042_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 546.0
PYH2_k127_3810042_3 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 534.0
PYH2_k127_3810042_4 cellulase activity K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 441.0
PYH2_k127_3810042_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 401.0
PYH2_k127_3810042_6 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 359.0
PYH2_k127_3810042_7 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000003443 136.0
PYH2_k127_3810042_8 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000009198 117.0
PYH2_k127_3810042_9 response regulator receiver K02481 - - 0.00000000000000000000005482 111.0
PYH2_k127_3832747_0 Vitamin k epoxide reductase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 315.0
PYH2_k127_3832747_1 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 301.0
PYH2_k127_3832747_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000002488 178.0
PYH2_k127_3832747_3 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000001503 139.0
PYH2_k127_3832747_4 - K19341 - - 0.0000000000000000000000000000003612 127.0
PYH2_k127_3832747_5 NosL K19342 - - 0.00000000000000000000000000003221 122.0
PYH2_k127_3832747_6 Cytochrome c K03611 - - 0.000000000000000000000000000412 118.0
PYH2_k127_3832747_8 - - - - 0.0000003234 59.0
PYH2_k127_3845498_0 nitrogen compound transport K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 260.0
PYH2_k127_3845498_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000702 254.0
PYH2_k127_3851254_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 424.0
PYH2_k127_3851254_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000003855 106.0
PYH2_k127_3851254_2 PD-(D/E)XK nuclease superfamily - - - 0.0000000005422 59.0
PYH2_k127_385978_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
PYH2_k127_385978_1 extracellular polysaccharide biosynthetic process K13582 - - 0.000000000000000000000000000000001272 143.0
PYH2_k127_385978_2 Belongs to the ClpA ClpB family K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000001043 72.0
PYH2_k127_3866621_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 378.0
PYH2_k127_3866621_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000008223 237.0
PYH2_k127_3866621_2 metallopeptidase activity - - - 0.0000007966 63.0
PYH2_k127_3866621_3 Glycosyl transferase 4-like domain - - - 0.000002471 56.0
PYH2_k127_3866621_4 Glyco_18 K06306 - - 0.00009672 55.0
PYH2_k127_3873959_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 531.0
PYH2_k127_3873959_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 297.0
PYH2_k127_3873959_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000004349 162.0
PYH2_k127_3873959_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000008736 104.0
PYH2_k127_3873959_4 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000002563 98.0
PYH2_k127_3873959_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000006451 85.0
PYH2_k127_3875698_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 369.0
PYH2_k127_3875698_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057,K02564 - 3.1.1.31,3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002211 258.0
PYH2_k127_3875698_2 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000002285 108.0
PYH2_k127_3875698_3 - - - - 0.000000001814 62.0
PYH2_k127_3876023_0 Aminotransferase class-III - - - 2.05e-214 678.0
PYH2_k127_3876023_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 536.0
PYH2_k127_3876023_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 368.0
PYH2_k127_3876023_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002907 244.0
PYH2_k127_3876023_4 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000003639 178.0
PYH2_k127_3876023_5 nuclease K01174 - 3.1.31.1 0.000000000000000000000000000000000004867 143.0
PYH2_k127_3880376_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005598 263.0
PYH2_k127_3880376_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000004115 231.0
PYH2_k127_3880376_2 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000006829 168.0
PYH2_k127_3880376_3 NUDIX domain - - - 0.00000000000000953 79.0
PYH2_k127_3882171_0 ATPase AAA-2 domain protein K03696 - - 0.0 1065.0
PYH2_k127_3882171_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.212e-243 771.0
PYH2_k127_3882171_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 363.0
PYH2_k127_3882171_11 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 352.0
PYH2_k127_3882171_12 PFAM peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 349.0
PYH2_k127_3882171_13 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
PYH2_k127_3882171_14 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000008046 214.0
PYH2_k127_3882171_15 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000005271 150.0
PYH2_k127_3882171_16 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000009756 140.0
PYH2_k127_3882171_17 enterobactin catabolic process K07214 - - 0.00000000000000000000000000000002796 139.0
PYH2_k127_3882171_18 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000007594 98.0
PYH2_k127_3882171_19 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000003252 87.0
PYH2_k127_3882171_2 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 535.0
PYH2_k127_3882171_20 peptidase M24 K01271 - 3.4.13.9 0.00000000002621 68.0
PYH2_k127_3882171_21 gas vesicle protein - - - 0.0002036 47.0
PYH2_k127_3882171_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 522.0
PYH2_k127_3882171_4 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 483.0
PYH2_k127_3882171_5 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 407.0
PYH2_k127_3882171_6 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 392.0
PYH2_k127_3882171_7 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 383.0
PYH2_k127_3882171_8 Magnesium transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 372.0
PYH2_k127_3882171_9 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 374.0
PYH2_k127_3893151_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 360.0
PYH2_k127_3893151_1 PFAM Alpha amylase, catalytic domain K00690 - 2.4.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 313.0
PYH2_k127_3893151_2 PFAM CBS domain containing protein - - - 0.0005538 45.0
PYH2_k127_391830_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 599.0
PYH2_k127_391830_1 protein kinase activity K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 354.0
PYH2_k127_391830_2 Domain of unknown function (DUF697) K08990 - - 0.000000000000000000000000000000000000000000000000000001302 203.0
PYH2_k127_391830_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000001031 155.0
PYH2_k127_391830_4 - - - - 0.0000000000003432 75.0
PYH2_k127_391830_5 Restriction endonuclease K07448 - - 0.0002229 48.0
PYH2_k127_3932458_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.505e-302 948.0
PYH2_k127_3932458_1 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 359.0
PYH2_k127_3932458_2 Creatinase/Prolidase N-terminal domain K01262,K01271,K08326 GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 337.0
PYH2_k127_3932458_3 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 316.0
PYH2_k127_3932458_4 - - - - 0.0005528 49.0
PYH2_k127_3933847_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 467.0
PYH2_k127_3933847_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 387.0
PYH2_k127_3933847_2 Phenylacetic acid degradation operon negative regulatory protein PaaX K02616 - - 0.0000000000000000000000000000000000000000000000000000000000001603 222.0
PYH2_k127_3933847_3 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000009767 216.0
PYH2_k127_3933847_4 GAF domain K07673 - 2.7.13.3 0.0000000000000000000000004509 114.0
PYH2_k127_3955139_0 histidine kinase A domain protein - - - 6.697e-258 891.0
PYH2_k127_3955139_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 585.0
PYH2_k127_3955139_10 TIGRFAM small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 289.0
PYH2_k127_3955139_11 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000009024 239.0
PYH2_k127_3955139_12 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000008375 227.0
PYH2_k127_3955139_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000008084 213.0
PYH2_k127_3955139_14 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000003628 163.0
PYH2_k127_3955139_15 response regulator K07657 - - 0.0000000000000000000000000002188 136.0
PYH2_k127_3955139_16 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000009319 119.0
PYH2_k127_3955139_17 Belongs to the DapA family K18123 - 4.1.3.16 0.000000000000000000001015 96.0
PYH2_k127_3955139_18 - - - - 0.000000000000001328 78.0
PYH2_k127_3955139_19 DNA polymerase K02337,K14162 - 2.7.7.7 0.000000000001866 68.0
PYH2_k127_3955139_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 531.0
PYH2_k127_3955139_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 454.0
PYH2_k127_3955139_4 Shikimate quinate 5-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 386.0
PYH2_k127_3955139_5 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 377.0
PYH2_k127_3955139_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 371.0
PYH2_k127_3955139_7 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 363.0
PYH2_k127_3955139_8 'ABC-type branched-chain amino acid transport K01999,K11954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 338.0
PYH2_k127_3955139_9 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 292.0
PYH2_k127_3963795_0 Transposase Tn5 dimerisation domain - - - 9.943e-228 728.0
PYH2_k127_3963795_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003491 252.0
PYH2_k127_3963795_2 Cyclophilin-like K09143 - - 0.0009165 42.0
PYH2_k127_3967487_0 Helix-turn-helix type 11 domain protein K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 301.0
PYH2_k127_3967487_1 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000009461 188.0
PYH2_k127_3967487_2 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000004063 183.0
PYH2_k127_3967487_3 PFAM Carbohydrate-binding module 48 (Isoamylase N-terminal domain) - - - 0.00000000000000000000000001443 112.0
PYH2_k127_3970171_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 447.0
PYH2_k127_3970171_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
PYH2_k127_3970171_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 256.0
PYH2_k127_3970171_3 PFAM extracellular solute-binding protein family 1 K02040 - - 0.00000000000000000000000000000000007529 144.0
PYH2_k127_3970171_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000002874 107.0
PYH2_k127_3970171_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000005491 91.0
PYH2_k127_3970171_6 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000003157 85.0
PYH2_k127_3970171_7 HEAT repeats - - - 0.000001394 57.0
PYH2_k127_3975398_0 spore germination K03298 - - 0.0000000000000000000000000000000000000000000000000000000000004678 221.0
PYH2_k127_3975398_1 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000212 172.0
PYH2_k127_3975398_2 Transcriptional regulator K02019,K05772 - - 0.00000000000000000000000000697 113.0
PYH2_k127_3975398_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000005065 103.0
PYH2_k127_3978697_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000003135 208.0
PYH2_k127_3978697_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000001502 114.0
PYH2_k127_3978697_2 Domain of unknown function (DUF333) K14475 - - 0.000000000000003012 85.0
PYH2_k127_3978697_3 Domain of unknown function (DUF333) K14475 - - 0.0000000000009601 81.0
PYH2_k127_3984380_0 Tricorn protease homolog K08676 - - 0.0 1283.0
PYH2_k127_3984380_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 363.0
PYH2_k127_3984380_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 293.0
PYH2_k127_3984380_3 Intracellular protease K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000007872 243.0
PYH2_k127_3984380_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000009631 240.0
PYH2_k127_3984380_5 RNase_H superfamily - - - 0.0000000000000000000000000000000000000003035 162.0
PYH2_k127_3984380_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000009603 87.0
PYH2_k127_3984380_7 SCP-2 sterol transfer family - - - 0.000000000000000009336 88.0
PYH2_k127_3984380_8 Peptidase MA superfamily - - - 0.0000000000000005515 83.0
PYH2_k127_4025464_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 576.0
PYH2_k127_4025464_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004254 273.0
PYH2_k127_4025464_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000002152 149.0
PYH2_k127_4025464_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000002246 138.0
PYH2_k127_4034381_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1894.0
PYH2_k127_4043098_0 PFAM Dak phosphatase K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 498.0
PYH2_k127_4043098_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
PYH2_k127_4043098_2 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000001911 228.0
PYH2_k127_4043098_3 PFAM DegV family protein - - - 0.0000000000000000000000000000000000000000000000000002365 195.0
PYH2_k127_4043098_4 Asp23 family, cell envelope-related function - - - 0.000000000000000000000002424 110.0
PYH2_k127_4043098_5 Ribosomal L28 family K02902 - - 0.00000000002138 66.0
PYH2_k127_4043098_6 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00005057 53.0
PYH2_k127_4055421_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.243e-242 764.0
PYH2_k127_4055421_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000004254 143.0
PYH2_k127_4055421_2 TIGRFAM Addiction module toxin, RelE StbE - - - 0.0000000000000000000000000000001552 125.0
PYH2_k127_4055421_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000001509 80.0
PYH2_k127_4055421_4 - - - - 0.000000007581 59.0
PYH2_k127_4055551_0 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 361.0
PYH2_k127_4055551_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000115 279.0
PYH2_k127_4055551_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001657 246.0
PYH2_k127_4055551_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000008169 104.0
PYH2_k127_4071942_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1762.0
PYH2_k127_4071942_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.282e-247 790.0
PYH2_k127_4071942_10 Heat shock protein DnaJ domain protein - - - 0.00000000002909 74.0
PYH2_k127_4071942_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 442.0
PYH2_k127_4071942_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 398.0
PYH2_k127_4071942_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 329.0
PYH2_k127_4071942_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002603 256.0
PYH2_k127_4071942_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000003064 218.0
PYH2_k127_4071942_7 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001392 206.0
PYH2_k127_4071942_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000004825 191.0
PYH2_k127_4071942_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000002053 193.0
PYH2_k127_4080926_0 histidine kinase A domain protein - - - 3.208e-264 862.0
PYH2_k127_4080926_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 454.0
PYH2_k127_4080926_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 326.0
PYH2_k127_4080926_3 Cobalamin B12-binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000005091 204.0
PYH2_k127_4088723_0 GMC oxidoreductase - - - 7.745e-214 680.0
PYH2_k127_4088723_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 9.896e-211 668.0
PYH2_k127_4088723_2 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 338.0
PYH2_k127_4088723_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 316.0
PYH2_k127_4088723_4 COG0395 ABC-type sugar transport system, permease component K02026,K10242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 296.0
PYH2_k127_4088723_5 Bacterial extracellular solute-binding protein K02027,K10120 - - 0.000000000000000000000000000000000000000000000000000007216 206.0
PYH2_k127_4088723_6 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000009157 118.0
PYH2_k127_4088723_7 Luciferase-like monooxygenase - - - 0.00000009362 55.0
PYH2_k127_411322_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 589.0
PYH2_k127_411322_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 558.0
PYH2_k127_411322_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 407.0
PYH2_k127_411322_3 - - - - 0.000000000000000000000000000000000008165 140.0
PYH2_k127_411322_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000007585 124.0
PYH2_k127_411322_5 Allergen V5 Tpx-1 family protein - - - 0.0000000000000003279 93.0
PYH2_k127_411322_6 Fungalysin/Thermolysin Propeptide Motif - - - 0.000003091 61.0
PYH2_k127_411322_7 Belongs to the complex I subunit 6 family K05578 - 1.6.5.3 0.000004204 52.0
PYH2_k127_411322_8 Xanthine dehydrogenase K11177 - 1.17.1.4 0.00008505 48.0
PYH2_k127_4116145_0 Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 416.0
PYH2_k127_4116145_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 301.0
PYH2_k127_4142039_0 FAD dependent oxidoreductase - - - 1.41e-260 814.0
PYH2_k127_4142039_1 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 601.0
PYH2_k127_4142039_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 481.0
PYH2_k127_4142039_3 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002353 224.0
PYH2_k127_4142039_4 Transposase DDE domain - - - 0.000000000000000000000000000002122 120.0
PYH2_k127_4142039_5 SnoaL-like domain - - - 0.000000000000000002416 93.0
PYH2_k127_4142039_6 reverse transcriptase K00986 - 2.7.7.49 0.0001658 50.0
PYH2_k127_4145428_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.093e-243 757.0
PYH2_k127_4145428_1 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 400.0
PYH2_k127_4145428_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 287.0
PYH2_k127_4145428_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004962 246.0
PYH2_k127_4145428_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000003278 235.0
PYH2_k127_4145428_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000005149 151.0
PYH2_k127_4145428_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000001251 64.0
PYH2_k127_4146413_0 epimerase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 536.0
PYH2_k127_4146413_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 451.0
PYH2_k127_4146413_10 - - - - 0.000000000000000000000000000006951 124.0
PYH2_k127_4146413_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 423.0
PYH2_k127_4146413_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 349.0
PYH2_k127_4146413_4 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002065 277.0
PYH2_k127_4146413_5 LPXTG-motif cell wall anchor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007266 238.0
PYH2_k127_4146413_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
PYH2_k127_4146413_7 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002232 218.0
PYH2_k127_4146413_8 Redoxin - - - 0.0000000000000000000000000000000000001076 146.0
PYH2_k127_4146413_9 Staygreen protein - - - 0.000000000000000000000000000000000002249 146.0
PYH2_k127_4153508_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 337.0
PYH2_k127_4153508_1 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000001977 120.0
PYH2_k127_4153508_2 Glyoxalase-like domain - - - 0.000000004176 60.0
PYH2_k127_4153508_3 Acetyltransferase (GNAT) domain - - - 0.0002677 46.0
PYH2_k127_4155434_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 484.0
PYH2_k127_4155434_1 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 322.0
PYH2_k127_4155434_2 (Rhomboid) family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000001165 220.0
PYH2_k127_4155434_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000002426 94.0
PYH2_k127_4155434_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000001585 101.0
PYH2_k127_4155434_5 - - - - 0.000000000000001139 81.0
PYH2_k127_415661_0 histidine kinase A domain protein K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 367.0
PYH2_k127_415661_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 335.0
PYH2_k127_415661_2 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 291.0
PYH2_k127_415661_3 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 288.0
PYH2_k127_415661_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000803 250.0
PYH2_k127_415661_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000003506 145.0
PYH2_k127_415661_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000007479 119.0
PYH2_k127_415661_7 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000000000001071 102.0
PYH2_k127_415661_8 domain protein - - - 0.0000002477 65.0
PYH2_k127_415661_9 - - - - 0.000297 51.0
PYH2_k127_4185681_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 316.0
PYH2_k127_4185681_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000158 288.0
PYH2_k127_4185681_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000006692 209.0
PYH2_k127_4185681_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000001007 153.0
PYH2_k127_4185681_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000005946 125.0
PYH2_k127_4185681_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000001685 82.0
PYH2_k127_4185681_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000002347 76.0
PYH2_k127_4185681_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000003026 59.0
PYH2_k127_4185728_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 334.0
PYH2_k127_4185728_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001972 265.0
PYH2_k127_4185728_2 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003875 214.0
PYH2_k127_4185728_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000003256 177.0
PYH2_k127_4185728_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002291 102.0
PYH2_k127_4185728_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000004435 75.0
PYH2_k127_4195820_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.42e-296 925.0
PYH2_k127_4195820_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.056e-255 797.0
PYH2_k127_4195820_10 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 340.0
PYH2_k127_4195820_11 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005703 301.0
PYH2_k127_4195820_12 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000319 276.0
PYH2_k127_4195820_13 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000003307 249.0
PYH2_k127_4195820_14 PFAM metalloenzyme domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003449 247.0
PYH2_k127_4195820_15 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000002052 244.0
PYH2_k127_4195820_16 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000009945 225.0
PYH2_k127_4195820_18 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000002259 208.0
PYH2_k127_4195820_19 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000002228 190.0
PYH2_k127_4195820_2 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 559.0
PYH2_k127_4195820_20 Glycosyl transferase family 21 K11936 - - 0.0000000000000000000000000000000000000000000000004704 190.0
PYH2_k127_4195820_21 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000001401 173.0
PYH2_k127_4195820_22 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000007489 185.0
PYH2_k127_4195820_23 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000004927 172.0
PYH2_k127_4195820_24 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000344 154.0
PYH2_k127_4195820_25 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.000000000000000000000000000000000002817 155.0
PYH2_k127_4195820_26 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000002322 144.0
PYH2_k127_4195820_27 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000001754 135.0
PYH2_k127_4195820_28 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000001325 127.0
PYH2_k127_4195820_29 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000005446 119.0
PYH2_k127_4195820_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 539.0
PYH2_k127_4195820_30 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000009284 85.0
PYH2_k127_4195820_31 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.00000000000009673 83.0
PYH2_k127_4195820_32 Uncharacterised nucleotidyltransferase - - - 0.000000000005214 78.0
PYH2_k127_4195820_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002543 61.0
PYH2_k127_4195820_4 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 514.0
PYH2_k127_4195820_5 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 489.0
PYH2_k127_4195820_6 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 493.0
PYH2_k127_4195820_7 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 392.0
PYH2_k127_4195820_8 PFAM Binding-protein-dependent transport system inner membrane component K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 374.0
PYH2_k127_4195820_9 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 351.0
PYH2_k127_4220867_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
PYH2_k127_4220867_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000003585 186.0
PYH2_k127_4220867_2 - - - - 0.0005736 49.0
PYH2_k127_422831_0 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 355.0
PYH2_k127_422831_1 the in vivo substrate is - - - 0.00000000000004272 80.0
PYH2_k127_4253280_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 1.6e-242 771.0
PYH2_k127_4253280_1 Predicted integral membrane protein (DUF2270) - - - 0.00000000000000000000000000000000000000000000000000000000004648 219.0
PYH2_k127_4253280_2 membrane - - - 0.000000000000001063 89.0
PYH2_k127_4261605_0 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 529.0
PYH2_k127_4261605_1 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000008896 150.0
PYH2_k127_4261605_2 ThiS family K03636 - - 0.000000000000000000000000000002805 122.0
PYH2_k127_4261605_3 photosynthesis - - - 0.00000000000001282 87.0
PYH2_k127_4261605_4 Glutaredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000001799 55.0
PYH2_k127_4340874_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 451.0
PYH2_k127_4341707_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 514.0
PYH2_k127_4341707_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000003859 217.0
PYH2_k127_4385998_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.906e-241 765.0
PYH2_k127_4385998_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 529.0
PYH2_k127_4385998_10 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0001609 47.0
PYH2_k127_4385998_2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009928 264.0
PYH2_k127_4385998_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins K03217 GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - 0.000000000000000000000000000000000000005839 154.0
PYH2_k127_4385998_4 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000495 136.0
PYH2_k127_4385998_5 Haemolytic - - - 0.000000000000000000000000000005313 122.0
PYH2_k127_4385998_6 HD domain K00951 - 2.7.6.5 0.0000000000000000000000000006252 113.0
PYH2_k127_4385998_8 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000003635 83.0
PYH2_k127_4385998_9 Ribosomal protein L34 K02914 - - 0.0000000004574 61.0
PYH2_k127_439267_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 351.0
PYH2_k127_439267_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 333.0
PYH2_k127_439267_2 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000000000000000000000000000001831 233.0
PYH2_k127_439267_3 - - - - 0.00000000000000000000000000000000000000000000000000001295 208.0
PYH2_k127_439267_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000006324 162.0
PYH2_k127_439267_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000001273 141.0
PYH2_k127_439267_6 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000002304 153.0
PYH2_k127_4416594_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 321.0
PYH2_k127_4416594_1 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 302.0
PYH2_k127_4416594_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 296.0
PYH2_k127_4416594_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002631 250.0
PYH2_k127_4416594_4 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000001761 190.0
PYH2_k127_4438521_0 Multicopper oxidase - - - 6.762e-316 988.0
PYH2_k127_4438521_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 296.0
PYH2_k127_4438521_10 ig-like, plexins, transcription factors - - - 0.00000000000000000000000000002917 137.0
PYH2_k127_4438521_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000006865 89.0
PYH2_k127_4438521_2 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006428 293.0
PYH2_k127_4438521_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001705 311.0
PYH2_k127_4438521_4 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000001555 217.0
PYH2_k127_4438521_5 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000001275 204.0
PYH2_k127_4438521_6 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000001324 186.0
PYH2_k127_4438521_7 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000005599 181.0
PYH2_k127_4438521_8 photoreceptor activity - - - 0.000000000000000000000000000000000000008167 170.0
PYH2_k127_4438521_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000000000000000000000000000002031 131.0
PYH2_k127_4467647_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 384.0
PYH2_k127_4467647_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 360.0
PYH2_k127_4467647_2 Protein of unknown function with PCYCGC motif - - - 0.000000000000000000000000001709 117.0
PYH2_k127_4467647_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000504 108.0
PYH2_k127_4467647_4 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.00000000000006301 83.0
PYH2_k127_4467647_5 Cytochrome c - - - 0.00000004277 65.0
PYH2_k127_4467647_6 PFAM NapC NirT cytochrome c family, N-terminal region K02569,K03532,K15876 - - 0.00000005056 62.0
PYH2_k127_4470828_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 1.726e-205 646.0
PYH2_k127_4470828_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 582.0
PYH2_k127_4470828_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 550.0
PYH2_k127_4470828_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000005261 213.0
PYH2_k127_4470828_4 periplasmic ligand-binding sensor domain - - - 0.00007617 54.0
PYH2_k127_4478558_0 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 505.0
PYH2_k127_4478558_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 458.0
PYH2_k127_4478558_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 455.0
PYH2_k127_4478558_3 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 360.0
PYH2_k127_4498574_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 6.314e-303 934.0
PYH2_k127_4498574_1 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 1.559e-208 669.0
PYH2_k127_4498574_10 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000003807 99.0
PYH2_k127_4498574_11 Roadblock/LC7 domain K07131 - - 0.000000000000003027 81.0
PYH2_k127_4498574_2 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 2.501e-203 651.0
PYH2_k127_4498574_3 sodium-dependent phosphate transmembrane transporter activity K03324,K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 315.0
PYH2_k127_4498574_4 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 295.0
PYH2_k127_4498574_5 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
PYH2_k127_4498574_6 TrkA-N domain K03499,K10716 - - 0.000000000000000000000000000000000000000000000000000005079 197.0
PYH2_k127_4498574_7 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000001326 176.0
PYH2_k127_4498574_8 GGDEF domain - - - 0.000000000000000000000000000158 128.0
PYH2_k127_4498574_9 AMP binding - - - 0.000000000000000000000000002619 122.0
PYH2_k127_451764_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 376.0
PYH2_k127_451764_1 TIGRFAM Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 309.0
PYH2_k127_4521159_0 ADP binding - - - 3.626e-218 707.0
PYH2_k127_4521159_1 ADP binding - - - 6.856e-209 681.0
PYH2_k127_4521159_10 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000005852 122.0
PYH2_k127_4521159_11 cellulase activity - - - 0.0000000000000000000005903 113.0
PYH2_k127_4521159_12 phosphoserine phosphatase activity K04757 - 2.7.11.1 0.000000000000000000003433 98.0
PYH2_k127_4521159_13 phosphorelay signal transduction system - - - 0.0000000007154 62.0
PYH2_k127_4521159_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 461.0
PYH2_k127_4521159_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 370.0
PYH2_k127_4521159_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 333.0
PYH2_k127_4521159_5 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
PYH2_k127_4521159_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000008291 221.0
PYH2_k127_4521159_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000001389 186.0
PYH2_k127_4521159_8 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000000000000000771 185.0
PYH2_k127_4521159_9 - - - - 0.000000000000000000000000000004183 126.0
PYH2_k127_452640_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1201.0
PYH2_k127_452640_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 488.0
PYH2_k127_452640_10 membrane - - - 0.0008326 44.0
PYH2_k127_452640_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 410.0
PYH2_k127_452640_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 353.0
PYH2_k127_452640_4 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 297.0
PYH2_k127_452640_5 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003681 293.0
PYH2_k127_452640_6 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001597 264.0
PYH2_k127_452640_7 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000129 238.0
PYH2_k127_452640_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000008752 228.0
PYH2_k127_4547764_0 PFAM AAA ATPase central domain protein K07478 - - 7.747e-208 660.0
PYH2_k127_4547764_1 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 391.0
PYH2_k127_4547764_10 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000426 116.0
PYH2_k127_4547764_11 Acetyltransferase (GNAT) domain - - - 0.000000000000003721 83.0
PYH2_k127_4547764_2 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 320.0
PYH2_k127_4547764_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001867 291.0
PYH2_k127_4547764_4 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009081 245.0
PYH2_k127_4547764_5 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000001271 234.0
PYH2_k127_4547764_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000005079 197.0
PYH2_k127_4547764_7 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000008424 173.0
PYH2_k127_4547764_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000198 153.0
PYH2_k127_4547764_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005275 157.0
PYH2_k127_4553771_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 4.787e-211 664.0
PYH2_k127_4553771_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 507.0
PYH2_k127_4553771_10 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000001687 250.0
PYH2_k127_4553771_11 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000005061 220.0
PYH2_k127_4553771_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000001193 220.0
PYH2_k127_4553771_13 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000002951 179.0
PYH2_k127_4553771_14 PFAM Bacterial protein of - - - 0.0000000000000000000000000000002899 132.0
PYH2_k127_4553771_2 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 353.0
PYH2_k127_4553771_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 356.0
PYH2_k127_4553771_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 334.0
PYH2_k127_4553771_5 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 318.0
PYH2_k127_4553771_6 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 323.0
PYH2_k127_4553771_7 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
PYH2_k127_4553771_8 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001701 268.0
PYH2_k127_4553771_9 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002566 267.0
PYH2_k127_4661259_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1323.0
PYH2_k127_4661259_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.646e-270 866.0
PYH2_k127_4661259_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000001012 179.0
PYH2_k127_4661259_3 - - - - 0.0000000000000000000201 97.0
PYH2_k127_4661259_4 glyoxalase III activity - - - 0.000000000002575 76.0
PYH2_k127_4661259_5 Peptidase family M28 - - - 0.00005068 54.0
PYH2_k127_4662379_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 466.0
PYH2_k127_4662379_1 -O-antigen K13009,K18814 - - 0.000000000000000000000006061 117.0
PYH2_k127_4662379_2 nucleotidyltransferase activity - - - 0.00000000000322 69.0
PYH2_k127_467124_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 546.0
PYH2_k127_467124_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 513.0
PYH2_k127_467124_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 442.0
PYH2_k127_467124_3 aminopeptidase activity K19701,K19702 - 3.4.11.10,3.4.11.24,3.4.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 409.0
PYH2_k127_467124_4 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 329.0
PYH2_k127_467124_5 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 299.0
PYH2_k127_467124_6 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 299.0
PYH2_k127_467124_7 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000004685 216.0
PYH2_k127_4680083_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 523.0
PYH2_k127_4695656_0 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 430.0
PYH2_k127_4695656_1 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000001095 115.0
PYH2_k127_4695656_2 PFAM copper amine oxidase domain protein - - - 0.0000000007971 71.0
PYH2_k127_4706423_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000003155 170.0
PYH2_k127_4706423_1 Pfam O-Antigen Polymerase - - - 0.000000000000000000000000000000002643 147.0
PYH2_k127_4731820_0 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000307 150.0
PYH2_k127_4731820_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000003528 145.0
PYH2_k127_4731820_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000001765 114.0
PYH2_k127_4731820_3 Haloacid dehalogenase-like hydrolase - - - 0.0006157 48.0
PYH2_k127_4734378_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 602.0
PYH2_k127_4734378_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 505.0
PYH2_k127_4734378_10 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000006062 203.0
PYH2_k127_4734378_11 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000001312 177.0
PYH2_k127_4734378_12 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000003154 160.0
PYH2_k127_4734378_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000000005958 139.0
PYH2_k127_4734378_14 TfoX N-terminal domain - - - 0.000000000000000000000000000000002639 133.0
PYH2_k127_4734378_15 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000001984 87.0
PYH2_k127_4734378_16 nucleotidyltransferase activity - - - 0.0009021 50.0
PYH2_k127_4734378_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 501.0
PYH2_k127_4734378_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 419.0
PYH2_k127_4734378_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 306.0
PYH2_k127_4734378_5 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 284.0
PYH2_k127_4734378_6 PFAM Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003907 298.0
PYH2_k127_4734378_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001548 242.0
PYH2_k127_4734378_8 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000006986 239.0
PYH2_k127_4734378_9 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000004842 206.0
PYH2_k127_4743968_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K02827 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009486,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015453,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0020037,GO:0022804,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1902600 1.10.3.10,1.10.3.12,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 592.0
PYH2_k127_4743968_1 Oligopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 572.0
PYH2_k127_4743968_10 Prokaryotic Cytochrome C oxidase subunit IV K02277,K02300 - 1.9.3.1 0.0002171 48.0
PYH2_k127_4743968_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 451.0
PYH2_k127_4743968_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006428 283.0
PYH2_k127_4743968_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000005846 243.0
PYH2_k127_4743968_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000002573 228.0
PYH2_k127_4743968_6 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000001133 203.0
PYH2_k127_4743968_7 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000001486 172.0
PYH2_k127_4743968_8 Protein of unknown function (DUF1706) - - - 0.00000000000001378 80.0
PYH2_k127_4743968_9 PFAM blue (type 1) copper domain protein - - - 0.0000000000005499 81.0
PYH2_k127_4760234_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1163.0
PYH2_k127_4760234_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 584.0
PYH2_k127_4760234_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 334.0
PYH2_k127_4760234_3 Domain of unknown function (DUF4380) - - - 0.000000000000000000000000000000000000000000000000000000000000000124 247.0
PYH2_k127_4760234_4 HNH endonuclease K07454 - - 0.00000000000002376 82.0
PYH2_k127_4760234_6 23S rRNA-intervening sequence protein - - - 0.0000000001624 67.0
PYH2_k127_4760234_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000003689 70.0
PYH2_k127_4760234_8 Ami_2 K11066 - 3.5.1.28 0.00001739 51.0
PYH2_k127_476476_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 498.0
PYH2_k127_476476_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000268 228.0
PYH2_k127_476476_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000001122 210.0
PYH2_k127_4770155_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 370.0
PYH2_k127_4770155_1 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
PYH2_k127_4770155_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000005274 112.0
PYH2_k127_4770155_3 Zeta toxin K07028 - - 0.00000000000000001297 84.0
PYH2_k127_4791807_0 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 304.0
PYH2_k127_4791807_1 Protein of unknown function (DUF4012) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005707 297.0
PYH2_k127_4791807_2 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000001026 229.0
PYH2_k127_4791807_3 PFAM Glycosyl transferase family 2 K07027 - - 0.000000003819 68.0
PYH2_k127_4791807_4 antibiotic catabolic process K18235 - - 0.0005437 49.0
PYH2_k127_4813131_0 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000002246 248.0
PYH2_k127_4813131_1 SdrD B-like domain - - - 0.000000000000000000000000000000000000000000000000000001112 218.0
PYH2_k127_4824606_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000007137 214.0
PYH2_k127_4824606_1 - - - - 0.000000000000000000003644 108.0
PYH2_k127_4824606_2 methyltransferase - - - 0.0000000000000001344 89.0
PYH2_k127_4824606_3 Glycosyltransferase family 87 - - - 0.00000000000009875 83.0
PYH2_k127_4824606_4 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.0000000000009888 81.0
PYH2_k127_4878592_0 PhoQ Sensor - - - 3.529e-259 832.0
PYH2_k127_4878592_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000007623 231.0
PYH2_k127_4878866_0 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000001503 126.0
PYH2_k127_4878866_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000000000003466 89.0
PYH2_k127_4878866_2 Glycosyl hydrolases family 15 - - - 0.0000000000000002021 80.0
PYH2_k127_4900549_0 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 387.0
PYH2_k127_4900549_1 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000003663 215.0
PYH2_k127_4928989_0 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001291 242.0
PYH2_k127_4928989_1 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000008382 229.0
PYH2_k127_4928989_2 4Fe-4S dicluster domain K00196 - - 0.00000217 51.0
PYH2_k127_4934497_0 ABC transporter K10441 - 3.6.3.17 1.215e-208 659.0
PYH2_k127_4934497_1 Periplasmic binding protein domain K10439 - - 1.901e-201 631.0
PYH2_k127_4934497_10 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 301.0
PYH2_k127_4934497_11 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000008637 164.0
PYH2_k127_4934497_12 GAF domain - - - 0.00000000000000000000000000000008909 137.0
PYH2_k127_4934497_13 NAD dependent epimerase/dehydratase family - - - 0.0000001628 60.0
PYH2_k127_4934497_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 582.0
PYH2_k127_4934497_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 524.0
PYH2_k127_4934497_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 464.0
PYH2_k127_4934497_5 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 443.0
PYH2_k127_4934497_6 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 415.0
PYH2_k127_4934497_7 PFAM ROK family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 352.0
PYH2_k127_4934497_8 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 344.0
PYH2_k127_4934497_9 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 303.0
PYH2_k127_4948185_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 436.0
PYH2_k127_4948185_1 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 316.0
PYH2_k127_4948185_2 LppX_LprAFG lipoprotein K14954 - - 0.0000000000000000000000000000000009147 140.0
PYH2_k127_4948185_3 Protein of unknown function (DUF433) - - - 0.0000000000000007621 82.0
PYH2_k127_4948185_4 Protein of unknown function (DUF3352) - - - 0.000000001476 70.0
PYH2_k127_4957024_0 PFAM extracellular solute-binding protein family 1 K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 490.0
PYH2_k127_4957024_1 PFAM Binding-protein-dependent transport system inner membrane component K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 401.0
PYH2_k127_4957024_2 glycerophosphodiester transmembrane transport K02026,K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 392.0
PYH2_k127_4957024_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 296.0
PYH2_k127_4957024_4 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000003341 175.0
PYH2_k127_4957024_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000002293 166.0
PYH2_k127_4987811_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000006875 82.0
PYH2_k127_4987811_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000002815 78.0
PYH2_k127_4987811_2 Ndr family - - - 0.000006207 58.0
PYH2_k127_4989588_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 548.0
PYH2_k127_4989588_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 377.0
PYH2_k127_4989588_2 Polysaccharide biosynthesis protein K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 302.0
PYH2_k127_4989588_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
PYH2_k127_4989588_4 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000002856 127.0
PYH2_k127_4989588_5 UbiA prenyltransferase family K20616 - - 0.0000000000000002375 90.0
PYH2_k127_4989588_6 Domain of unknown function (DUF4286) - - - 0.000000000000006875 79.0
PYH2_k127_4989588_7 PD-(D/E)XK nuclease superfamily - - - 0.0000008271 54.0
PYH2_k127_5012921_0 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000008414 202.0
PYH2_k127_5012921_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000001187 195.0
PYH2_k127_5012921_2 PFAM Auxin Efflux Carrier K07088 - - 0.00000000005943 69.0
PYH2_k127_503102_0 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
PYH2_k127_503102_1 Domain of unknown function (DUF4111) K00984 - 2.7.7.47 0.0000000000000000000000000000000000000000000000000000000000007483 222.0
PYH2_k127_503102_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002212 217.0
PYH2_k127_503102_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
PYH2_k127_503102_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000001343 196.0
PYH2_k127_503102_5 Carboxypeptidase regulatory-like domain K01365,K02030,K14475 - 3.4.22.15 0.00000000005293 64.0
PYH2_k127_503102_6 Sugar (and other) transporter - - - 0.0004972 46.0
PYH2_k127_5034000_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1798.0
PYH2_k127_5034000_1 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 481.0
PYH2_k127_5034000_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000001178 63.0
PYH2_k127_5034000_2 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 468.0
PYH2_k127_5034000_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 313.0
PYH2_k127_5034000_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003429 269.0
PYH2_k127_5034000_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001504 259.0
PYH2_k127_5034000_6 PFAM KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000002114 194.0
PYH2_k127_5034000_7 PFAM secretion protein HlyD family protein - - - 0.0000000000000000000000000000000000000000000005276 182.0
PYH2_k127_5034000_8 - - - - 0.00000000003899 75.0
PYH2_k127_5034000_9 transposase activity - - - 0.000000007796 57.0
PYH2_k127_5047835_0 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 330.0
PYH2_k127_5047835_1 NlpC/P60 family K20742,K21471 - 3.4.14.13 0.00000000000000000000000000000000000000000000000000007471 209.0
PYH2_k127_5047835_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000004675 170.0
PYH2_k127_5047835_3 Protein of unknown function (DUF433) - - - 0.000000000000000000000005684 105.0
PYH2_k127_5047835_4 Alpha beta hydrolase fold - - - 0.00000000000000000000002108 116.0
PYH2_k127_5047835_5 - - - - 0.0000000000000000000758 90.0
PYH2_k127_5072442_0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 377.0
PYH2_k127_5072442_1 PFAM Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 328.0
PYH2_k127_5072442_2 IMG reference gene - - - 0.00000000000000002745 85.0
PYH2_k127_5072442_3 COG3209 Rhs family protein - - - 0.0000000003456 68.0
PYH2_k127_5108192_0 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 565.0
PYH2_k127_5108192_1 TOBE domain K02062,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000002609 158.0
PYH2_k127_5108192_2 PIN domain - - - 0.000000000000000000000000001205 118.0
PYH2_k127_5108192_3 Belongs to the 'phage' integrase family - - - 0.0000003622 52.0
PYH2_k127_5108192_4 LVIVD repeat - - - 0.0001344 46.0
PYH2_k127_5171556_0 Heat shock 70 kDa protein K04043 - - 7.371e-291 904.0
PYH2_k127_5171556_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 435.0
PYH2_k127_5171556_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 313.0
PYH2_k127_5171556_3 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
PYH2_k127_5171556_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000576 228.0
PYH2_k127_5171556_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000003384 147.0
PYH2_k127_5171556_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000005096 119.0
PYH2_k127_5178157_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000005782 232.0
PYH2_k127_5178157_1 DNA-templated transcription, initiation K03088,K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000001077 180.0
PYH2_k127_5178157_2 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000004052 80.0
PYH2_k127_5207879_0 heme binding K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 336.0
PYH2_k127_5207879_1 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 278.0
PYH2_k127_5207879_2 Cell Wall K01448 - 3.5.1.28 0.000000000000000000000006717 119.0
PYH2_k127_5207879_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000004534 96.0
PYH2_k127_5207879_4 SMART zinc finger, RanBP2-type - - - 0.0000007392 59.0
PYH2_k127_5207879_5 Sh3 type 3 domain protein K01448 - 3.5.1.28 0.0002667 54.0
PYH2_k127_5246720_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.294e-199 634.0
PYH2_k127_5246720_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 465.0
PYH2_k127_5246720_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 445.0
PYH2_k127_5246720_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 432.0
PYH2_k127_5246720_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 406.0
PYH2_k127_5246720_5 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000006038 222.0
PYH2_k127_5246720_6 SNF2 family N-terminal domain - - - 0.0001615 53.0
PYH2_k127_5246720_7 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0003277 47.0
PYH2_k127_5253765_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 466.0
PYH2_k127_5253765_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 375.0
PYH2_k127_5253765_2 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000001115 172.0
PYH2_k127_5253765_3 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000286 120.0
PYH2_k127_5259489_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
PYH2_k127_5259489_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000002187 178.0
PYH2_k127_5291540_0 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 367.0
PYH2_k127_5291540_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 344.0
PYH2_k127_5291540_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000012 215.0
PYH2_k127_5291540_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000001742 162.0
PYH2_k127_5291540_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000001092 144.0
PYH2_k127_5291540_5 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000001131 108.0
PYH2_k127_5291540_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000002234 52.0
PYH2_k127_5307402_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 441.0
PYH2_k127_5307402_1 of the major facilitator superfamily - - - 0.0000000001112 64.0
PYH2_k127_5307402_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0002999 44.0
PYH2_k127_5328746_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 524.0
PYH2_k127_5328746_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 317.0
PYH2_k127_5328746_11 signal-transduction protein containing cAMP-binding and CBS domains K00384 - 1.8.1.9 0.000000000000000000006716 102.0
PYH2_k127_5328746_12 translation initiation factor activity - - - 0.00000005281 59.0
PYH2_k127_5328746_13 Tetratricopeptide repeat - - - 0.000192 55.0
PYH2_k127_5328746_14 Fungalysin/Thermolysin Propeptide Motif K08603 - 3.4.24.27 0.0003663 51.0
PYH2_k127_5328746_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 324.0
PYH2_k127_5328746_3 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 261.0
PYH2_k127_5328746_4 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000002361 225.0
PYH2_k127_5328746_5 - - - - 0.00000000000000000000000000000000000000000000000000000001242 199.0
PYH2_k127_5328746_6 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000000716 203.0
PYH2_k127_5328746_7 - - - - 0.000000000000000000000000000000000000000000000000000003656 195.0
PYH2_k127_5328746_8 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000002161 198.0
PYH2_k127_5328746_9 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000001428 138.0
PYH2_k127_5347705_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.931e-294 914.0
PYH2_k127_5347705_1 Rubrerythrin K22336 - 1.16.3.1 0.000000000000000000000000000000000000000000005278 169.0
PYH2_k127_5347705_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000001209 156.0
PYH2_k127_5347705_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000005538 105.0
PYH2_k127_5354291_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 604.0
PYH2_k127_5354291_1 RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
PYH2_k127_5354291_2 Hep Hag repeat protein - - - 0.000000000000000000000000000000001672 146.0
PYH2_k127_5354291_3 - - - - 0.00000000002129 67.0
PYH2_k127_5365754_0 ATP-grasp domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 521.0
PYH2_k127_5365754_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001472 271.0
PYH2_k127_5365754_2 Bacterial Fe(2+) trafficking - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.0000000000000000000000000000000000000003017 151.0
PYH2_k127_5365754_4 3-beta hydroxysteroid dehydrogenase isomerase K00091 - 1.1.1.219 0.000003635 50.0
PYH2_k127_5398527_0 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 553.0
PYH2_k127_5398527_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 455.0
PYH2_k127_5398527_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 426.0
PYH2_k127_5398527_3 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000004619 164.0
PYH2_k127_5398527_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000004886 161.0
PYH2_k127_5398527_5 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000008841 151.0
PYH2_k127_5398527_6 NNMT/PNMT/TEMT family - - - 0.0000000000000000000000000000004087 132.0
PYH2_k127_5481074_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 4.511e-252 787.0
PYH2_k127_5481074_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.579e-214 676.0
PYH2_k127_5481074_10 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000001098 105.0
PYH2_k127_5481074_11 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000003744 102.0
PYH2_k127_5481074_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 533.0
PYH2_k127_5481074_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 485.0
PYH2_k127_5481074_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 439.0
PYH2_k127_5481074_5 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 287.0
PYH2_k127_5481074_6 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
PYH2_k127_5481074_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000005346 152.0
PYH2_k127_5481074_8 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000001884 115.0
PYH2_k127_5481074_9 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001852 109.0
PYH2_k127_54912_0 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 297.0
PYH2_k127_54912_1 domain, Protein - - - 0.00000002768 65.0
PYH2_k127_54912_2 carboxylic ester hydrolase activity K14205 - 2.3.2.3 0.0001499 45.0
PYH2_k127_5499359_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 403.0
PYH2_k127_5499359_1 MFS_1 like family K08151,K08153 - - 0.0000000000000000000000000000000000000000000000000000000000007955 222.0
PYH2_k127_5499359_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000007981 206.0
PYH2_k127_5499359_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000006052 185.0
PYH2_k127_5499359_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000009631 104.0
PYH2_k127_5548328_0 Cytochrome c - - - 0.000000002694 66.0
PYH2_k127_5548328_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000512 58.0
PYH2_k127_5564875_0 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 2.371e-232 722.0
PYH2_k127_5564875_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 358.0
PYH2_k127_5564875_2 fumarylacetoacetate (FAA) hydrolase K14259 - 4.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 346.0
PYH2_k127_5564875_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
PYH2_k127_5564875_4 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000008065 172.0
PYH2_k127_5564875_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000004584 111.0
PYH2_k127_5564875_6 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000000000000006036 112.0
PYH2_k127_5585256_0 PFAM pentapeptide repeat protein - - - 0.00000000000000000000000000000000000008814 149.0
PYH2_k127_5585256_1 PIN domain - - - 0.000000000000000003109 89.0
PYH2_k127_5585256_2 - - - - 0.0000000001013 64.0
PYH2_k127_5607438_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 1.427e-215 679.0
PYH2_k127_5607438_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000001806 156.0
PYH2_k127_5607438_2 Histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000004343 108.0
PYH2_k127_5642681_0 - - - - 0.0000000000000000000000000000000000001285 159.0
PYH2_k127_5642681_1 integral membrane protein - - - 0.000000000000000000000000000005544 138.0
PYH2_k127_5642681_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000001069 77.0
PYH2_k127_5645318_0 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 364.0
PYH2_k127_5645318_1 DNA primase activity K02316,K17680 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000262 214.0
PYH2_k127_5645318_2 PFAM Transposase IS3 IS911 K07483 - - 0.000000000000000000001334 97.0
PYH2_k127_5670968_0 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 538.0
PYH2_k127_5670968_1 PFAM Integrase, catalytic region - - - 0.000000000001625 69.0
PYH2_k127_5672301_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 5.932e-293 915.0
PYH2_k127_5672301_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.396e-249 781.0
PYH2_k127_5672301_2 CoA-transferase family III - - - 0.000000000000000000000000000007229 122.0
PYH2_k127_5672301_3 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.00000000000000000000000000002954 119.0
PYH2_k127_5672301_4 Thioesterase-like superfamily - - - 0.000000000000000000004848 99.0
PYH2_k127_5676909_0 in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 563.0
PYH2_k127_5676909_1 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 349.0
PYH2_k127_5676909_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000001081 59.0
PYH2_k127_5683485_0 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000000000001968 147.0
PYH2_k127_5683485_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000002365 134.0
PYH2_k127_5683485_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000008489 132.0
PYH2_k127_5683485_3 Flagellar filament outer layer protein Flaa - - - 0.00000000000000009326 96.0
PYH2_k127_5683485_4 PFAM glycosyl transferase family 39 - - - 0.00000000000002268 85.0
PYH2_k127_5685800_0 Alpha amylase, catalytic domain - - - 0.0 1444.0
PYH2_k127_5685800_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 601.0
PYH2_k127_5685800_10 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000000000000002274 156.0
PYH2_k127_5685800_11 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000138 150.0
PYH2_k127_5685800_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000005067 148.0
PYH2_k127_5685800_13 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000003533 102.0
PYH2_k127_5685800_14 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000007094 100.0
PYH2_k127_5685800_15 AmiS/UreI family transporter K03191 - - 0.000000000000004827 82.0
PYH2_k127_5685800_16 Nitrate reductase gamma subunit - - - 0.000000000000007018 85.0
PYH2_k127_5685800_17 Bacterial transcriptional activator domain K03556 - - 0.00000000000004945 85.0
PYH2_k127_5685800_18 component of anaerobic dehydrogenases - - - 0.0000000000002151 78.0
PYH2_k127_5685800_19 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000391 67.0
PYH2_k127_5685800_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 395.0
PYH2_k127_5685800_20 - - - - 0.0000000009526 71.0
PYH2_k127_5685800_21 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.00000001488 56.0
PYH2_k127_5685800_22 protein secretion K03116 - - 0.000007137 53.0
PYH2_k127_5685800_23 XdhC and CoxI family K07402 - - 0.0000478 49.0
PYH2_k127_5685800_3 molybdopterin cofactor binding K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 376.0
PYH2_k127_5685800_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 335.0
PYH2_k127_5685800_5 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001179 274.0
PYH2_k127_5685800_6 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000202 241.0
PYH2_k127_5685800_7 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000001181 223.0
PYH2_k127_5685800_8 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000004343 213.0
PYH2_k127_5685800_9 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000005604 167.0
PYH2_k127_5710163_0 membrane protein, terc K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 599.0
PYH2_k127_5710163_1 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 563.0
PYH2_k127_5710163_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000009652 163.0
PYH2_k127_5710163_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000018 162.0
PYH2_k127_5710163_4 - - - - 0.00000000000000000000000000000000000317 141.0
PYH2_k127_5710163_5 PFAM amidohydrolase 2 - - - 0.000000000000000000000000002796 118.0
PYH2_k127_5711168_0 transport systems ATPase components K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 426.0
PYH2_k127_5711168_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005486 292.0
PYH2_k127_5711168_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002421 274.0
PYH2_k127_5711168_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000535 236.0
PYH2_k127_5711168_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000009644 234.0
PYH2_k127_5711168_5 Sigma-70, region 4 type 2 - - - 0.000000000000000000000000000000000000000000000000000008222 198.0
PYH2_k127_5711168_6 Cache_2 K02480 - 2.7.13.3 0.00000000000000000000000000009287 132.0
PYH2_k127_5711168_7 competence protein COMEC - - - 0.000007097 54.0
PYH2_k127_5715555_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 408.0
PYH2_k127_5715555_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000007862 126.0
PYH2_k127_5715555_2 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.000000000006638 69.0
PYH2_k127_5715555_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000653 53.0
PYH2_k127_5723187_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 342.0
PYH2_k127_5723187_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 336.0
PYH2_k127_5723187_10 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000003756 214.0
PYH2_k127_5723187_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000232 168.0
PYH2_k127_5723187_12 integral membrane protein - - - 0.000000000000000000000000000000000000000001171 172.0
PYH2_k127_5723187_13 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000005276 152.0
PYH2_k127_5723187_14 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000004829 116.0
PYH2_k127_5723187_15 transposase activity - - - 0.00000000000000004771 82.0
PYH2_k127_5723187_16 Signal transduction protein with Nacht domain - - - 0.000000000005535 79.0
PYH2_k127_5723187_17 ATP hydrolysis coupled proton transport - - - 0.00000001733 60.0
PYH2_k127_5723187_18 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.0006088 53.0
PYH2_k127_5723187_2 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 304.0
PYH2_k127_5723187_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000256 259.0
PYH2_k127_5723187_5 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008394 253.0
PYH2_k127_5723187_6 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
PYH2_k127_5723187_7 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003228 243.0
PYH2_k127_5723187_8 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000005912 237.0
PYH2_k127_5723187_9 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000003331 201.0
PYH2_k127_5727385_0 Protein of unknown function (DUF3616) - - - 1.698e-229 714.0
PYH2_k127_5727385_1 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 531.0
PYH2_k127_5727385_2 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 400.0
PYH2_k127_5727385_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
PYH2_k127_5727385_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002831 245.0
PYH2_k127_5727385_5 Evidence 4 Homologs of previously reported genes of K09981 - - 0.00000000000000000000000000000000000000002141 153.0
PYH2_k127_5727385_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000009498 144.0
PYH2_k127_5727385_7 PFAM Transposase DDE domain - - - 0.000000146 55.0
PYH2_k127_5735187_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1310.0
PYH2_k127_5735187_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1188.0
PYH2_k127_5735187_10 - - - - 0.00000000000000000000000000000000000000000000002596 182.0
PYH2_k127_5735187_11 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000001926 186.0
PYH2_k127_5735187_12 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000005485 143.0
PYH2_k127_5735187_13 DNA-binding transcription factor activity - - - 0.00000000000000000000006577 105.0
PYH2_k127_5735187_14 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000002905 93.0
PYH2_k127_5735187_15 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000004475 69.0
PYH2_k127_5735187_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 542.0
PYH2_k127_5735187_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 515.0
PYH2_k127_5735187_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 479.0
PYH2_k127_5735187_5 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 413.0
PYH2_k127_5735187_6 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 340.0
PYH2_k127_5735187_7 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
PYH2_k127_5735187_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000001129 198.0
PYH2_k127_5735187_9 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000008765 192.0
PYH2_k127_5740116_0 Glycogen debranching enzyme - - - 2.799e-229 724.0
PYH2_k127_5740116_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.071e-195 619.0
PYH2_k127_5740116_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 463.0
PYH2_k127_5740116_3 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 289.0
PYH2_k127_5740116_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 275.0
PYH2_k127_5740116_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005445 260.0
PYH2_k127_5740116_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000005012 154.0
PYH2_k127_5740116_7 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000004492 138.0
PYH2_k127_5740116_9 Transcriptional regulator - - - 0.00002827 55.0
PYH2_k127_5741909_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 426.0
PYH2_k127_5741909_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 383.0
PYH2_k127_5741909_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000000000009321 164.0
PYH2_k127_5747963_0 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 335.0
PYH2_k127_5747963_1 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000002025 163.0
PYH2_k127_5747963_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000023 58.0
PYH2_k127_5779955_0 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 553.0
PYH2_k127_5779955_1 Periplasmic solute binding protein K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 451.0
PYH2_k127_5779955_2 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 406.0
PYH2_k127_5779955_3 ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 347.0
PYH2_k127_5779955_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
PYH2_k127_5779955_5 Sodium:dicarboxylate symporter family - - - 0.0000000002734 64.0
PYH2_k127_5783970_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1269.0
PYH2_k127_5783970_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 370.0
PYH2_k127_5783970_3 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000003201 188.0
PYH2_k127_5783970_4 Transposase IS200 like - - - 0.00000000000000000000001759 107.0
PYH2_k127_5794549_0 Protein of unknown function, DUF255 K06888 - - 9.083e-244 771.0
PYH2_k127_5794549_1 ABC transporter K10548 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 611.0
PYH2_k127_5794549_2 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 537.0
PYH2_k127_5794549_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 472.0
PYH2_k127_5794549_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000002437 245.0
PYH2_k127_5794549_5 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000007609 177.0
PYH2_k127_5794549_6 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000003325 123.0
PYH2_k127_5794549_7 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000001594 84.0
PYH2_k127_5794549_8 Periplasmic binding protein domain K10546 - - 0.00000000000002551 72.0
PYH2_k127_5796870_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 550.0
PYH2_k127_5796870_1 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000001222 224.0
PYH2_k127_5796870_2 LysM domain K01447,K12204 - 3.5.1.28 0.000000000000000003487 98.0
PYH2_k127_5815556_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 571.0
PYH2_k127_5815556_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 376.0
PYH2_k127_5815556_10 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001119 225.0
PYH2_k127_5815556_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000002162 204.0
PYH2_k127_5815556_12 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000007553 190.0
PYH2_k127_5815556_13 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000005693 181.0
PYH2_k127_5815556_14 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000395 183.0
PYH2_k127_5815556_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000002096 165.0
PYH2_k127_5815556_16 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000006408 173.0
PYH2_k127_5815556_17 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000003831 153.0
PYH2_k127_5815556_18 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000001542 107.0
PYH2_k127_5815556_19 Tetratricopeptide repeat - - - 0.0000000000000000000003366 100.0
PYH2_k127_5815556_2 Histidine kinase K02480 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 381.0
PYH2_k127_5815556_20 STAS domain K17763 - - 0.00000000000001151 88.0
PYH2_k127_5815556_21 Fibronectin type 3 domain - - - 0.0005521 52.0
PYH2_k127_5815556_3 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 318.0
PYH2_k127_5815556_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 326.0
PYH2_k127_5815556_5 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003193 298.0
PYH2_k127_5815556_6 PFAM tRNA rRNA methyltransferase (SpoU) K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009281 254.0
PYH2_k127_5815556_7 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000008583 273.0
PYH2_k127_5815556_8 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000003786 243.0
PYH2_k127_5815556_9 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000908 223.0
PYH2_k127_5815611_0 Alkyl hydroperoxide reductase K03387 - - 3.674e-237 747.0
PYH2_k127_5815611_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 359.0
PYH2_k127_5815611_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000002696 213.0
PYH2_k127_5815611_3 Acid phosphatase homologues - - - 0.000000000000000000000000000000000002132 151.0
PYH2_k127_5815611_4 ChrR Cupin-like domain K20148 - 1.13.11.50 0.00000000000000000001391 94.0
PYH2_k127_5817942_0 Integral membrane sensor signal transduction histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.000000000000000000000000001891 123.0
PYH2_k127_5820696_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 501.0
PYH2_k127_5820696_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 432.0
PYH2_k127_5820696_2 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 335.0
PYH2_k127_5820696_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 299.0
PYH2_k127_5820696_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH2_k127_5820696_5 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000002151 238.0
PYH2_k127_5820696_6 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000822 174.0
PYH2_k127_5820696_7 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000004614 171.0
PYH2_k127_5820696_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000002788 121.0
PYH2_k127_5828148_0 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 608.0
PYH2_k127_5828148_1 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.000000000000000000000000000000000000000000000000000000000000000000002283 258.0
PYH2_k127_5828148_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000001071 250.0
PYH2_k127_5828148_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000006658 230.0
PYH2_k127_5828148_4 Protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000003462 203.0
PYH2_k127_5828148_5 Zinc finger domain - - - 0.000000000000000001961 92.0
PYH2_k127_5828148_6 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000000001491 72.0
PYH2_k127_5837084_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 484.0
PYH2_k127_5837084_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 482.0
PYH2_k127_5837084_10 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000004611 168.0
PYH2_k127_5837084_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000006691 165.0
PYH2_k127_5837084_12 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000001562 161.0
PYH2_k127_5837084_13 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000001095 165.0
PYH2_k127_5837084_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000009249 145.0
PYH2_k127_5837084_15 Rhodanese Homology Domain - - - 0.00000000000000000000000001387 113.0
PYH2_k127_5837084_16 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000002473 96.0
PYH2_k127_5837084_17 Lysine exporter protein LysE YggA - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - 0.000000000000000003284 93.0
PYH2_k127_5837084_18 amidinotransferase K01482 - 3.5.3.18 0.000000000000006868 78.0
PYH2_k127_5837084_2 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 454.0
PYH2_k127_5837084_20 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000005417 74.0
PYH2_k127_5837084_21 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000808 55.0
PYH2_k127_5837084_22 Protein of unknown function (DUF2283) - - - 0.0001659 47.0
PYH2_k127_5837084_3 ABC transporter K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 296.0
PYH2_k127_5837084_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
PYH2_k127_5837084_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003748 235.0
PYH2_k127_5837084_6 ABC transporter, permease protein K02029,K02030,K09971,K17062 - - 0.0000000000000000000000000000000000000000000000000000000000000006126 229.0
PYH2_k127_5837084_7 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000000000000000000004142 229.0
PYH2_k127_5837084_8 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000000000000000000000000001451 194.0
PYH2_k127_5837084_9 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000004173 175.0
PYH2_k127_5854193_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 334.0
PYH2_k127_5854193_1 - - - - 0.0000000000000002035 79.0
PYH2_k127_5873115_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1008.0
PYH2_k127_5873115_1 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
PYH2_k127_5873115_2 transporter K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 344.0
PYH2_k127_5873115_3 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000111 178.0
PYH2_k127_5873115_4 - - - - 0.0000000000000000000156 106.0
PYH2_k127_5873115_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000001491 88.0
PYH2_k127_5873115_6 XdhC Rossmann domain K07402 - - 0.0000000004449 60.0
PYH2_k127_5906617_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 464.0
PYH2_k127_5906617_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 327.0
PYH2_k127_5906617_2 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000208 243.0
PYH2_k127_5906617_3 transmembrane transport K22044 GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - 0.00000000000000000000000000000000000000000000006214 179.0
PYH2_k127_5906617_4 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000324 163.0
PYH2_k127_5916515_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 483.0
PYH2_k127_5916515_1 heat shock protein 70 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 336.0
PYH2_k127_5937444_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 585.0
PYH2_k127_5937444_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000003225 154.0
PYH2_k127_5937444_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000003378 141.0
PYH2_k127_5937444_3 serine-type aminopeptidase activity K14475 - - 0.00000000005176 72.0
PYH2_k127_5947079_0 Tetratricopeptide TPR_2 repeat protein - - - 5.085e-294 962.0
PYH2_k127_5947079_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 637.0
PYH2_k127_5947079_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004183 56.0
PYH2_k127_5947079_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 502.0
PYH2_k127_5947079_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 504.0
PYH2_k127_5947079_4 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 494.0
PYH2_k127_5947079_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 391.0
PYH2_k127_5947079_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 286.0
PYH2_k127_5947079_7 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000004156 201.0
PYH2_k127_5947079_8 PFAM conserved K07027 - - 0.000000000000000000000000000000000001774 151.0
PYH2_k127_5947079_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000006753 63.0
PYH2_k127_5947577_0 Histidine kinase K07675,K11623 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000007648 205.0
PYH2_k127_5947577_1 exo-alpha-(2->6)-sialidase activity K20276 - - 0.00000000000000000000000000000002448 134.0
PYH2_k127_5950491_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 352.0
PYH2_k127_5959545_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000005138 205.0
PYH2_k127_5959545_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000003067 170.0
PYH2_k127_5959545_2 O-Antigen ligase - - - 0.00000000004111 75.0
PYH2_k127_5959545_3 Glycosyl transferases group 1 K12995 - 2.4.1.348 0.0000005439 53.0
PYH2_k127_6057146_0 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000001271 148.0
PYH2_k127_6057146_2 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000001249 57.0
PYH2_k127_6061423_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 618.0
PYH2_k127_6061423_1 transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000213 205.0
PYH2_k127_6061423_11 Pfam:DUF59 - - - 0.0001959 47.0
PYH2_k127_6061423_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000001115 172.0
PYH2_k127_6061423_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000001986 156.0
PYH2_k127_6061423_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.00000000000000000000000000000000000008352 145.0
PYH2_k127_6061423_6 Belongs to the UPF0342 family - - - 0.0000000241 61.0
PYH2_k127_6061423_7 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000008098 59.0
PYH2_k127_6061423_8 Hep Hag repeat protein - - - 0.000002175 60.0
PYH2_k127_6075218_0 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000001081 226.0
PYH2_k127_6075218_1 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000004646 219.0
PYH2_k127_6075218_10 Psort location CytoplasmicMembrane, score - - - 0.00007893 54.0
PYH2_k127_6075218_2 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000000000000000000000000000000003997 206.0
PYH2_k127_6075218_3 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000003965 139.0
PYH2_k127_6075218_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000001589 147.0
PYH2_k127_6075218_5 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000002371 136.0
PYH2_k127_6075218_7 PFAM TadE family protein - - - 0.00000000000005233 83.0
PYH2_k127_6075218_8 TadE-like protein - - - 0.0000000001167 68.0
PYH2_k127_6081297_0 PFAM Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
PYH2_k127_6081297_1 IMG reference gene - - - 0.00000000000000000000008836 101.0
PYH2_k127_6106779_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000001567 100.0
PYH2_k127_6106779_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00001405 48.0
PYH2_k127_6106832_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 355.0
PYH2_k127_6106832_1 - - - - 0.0000000000000000003344 89.0
PYH2_k127_6154443_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1045.0
PYH2_k127_6154443_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.819e-311 981.0
PYH2_k127_6154443_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001768 222.0
PYH2_k127_6154443_11 -O-antigen - - - 0.000000000000000000000000000000000000008899 164.0
PYH2_k127_6154443_12 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000006653 137.0
PYH2_k127_6154443_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001147 136.0
PYH2_k127_6154443_14 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000009415 136.0
PYH2_k127_6154443_15 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000001636 101.0
PYH2_k127_6154443_16 Chromatin associated protein KTI12 - - - 0.00000000000000000004083 102.0
PYH2_k127_6154443_17 Peptidoglycan-binding lysin domain - - - 0.000000000001646 79.0
PYH2_k127_6154443_18 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000009587 55.0
PYH2_k127_6154443_2 DNA polymerase K02337,K14162 - 2.7.7.7 1.88e-197 652.0
PYH2_k127_6154443_3 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
PYH2_k127_6154443_4 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 361.0
PYH2_k127_6154443_5 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 316.0
PYH2_k127_6154443_6 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 325.0
PYH2_k127_6154443_7 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001364 263.0
PYH2_k127_6154443_8 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000003016 254.0
PYH2_k127_6154443_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
PYH2_k127_6171947_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 573.0
PYH2_k127_6171947_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 405.0
PYH2_k127_6171947_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 334.0
PYH2_k127_6171947_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 280.0
PYH2_k127_6171947_4 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000661 216.0
PYH2_k127_6171947_5 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.000000000000000000000000000000000000004236 156.0
PYH2_k127_6171947_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000003246 110.0
PYH2_k127_6171947_7 serine-type endopeptidase activity - - - 0.00000000000000000000002307 106.0
PYH2_k127_6175077_0 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006735 307.0
PYH2_k127_6175077_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007252 284.0
PYH2_k127_6175077_2 LamG domain protein jellyroll fold domain protein - - - 0.0000000008255 70.0
PYH2_k127_6175077_3 - - - - 0.00000001358 59.0
PYH2_k127_6175077_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000009853 51.0
PYH2_k127_6175991_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000002718 195.0
PYH2_k127_6175991_1 MaoC like domain - - - 0.000000000000000000000000000000000000000001092 162.0
PYH2_k127_6178591_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000036 256.0
PYH2_k127_6178591_1 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000001898 132.0
PYH2_k127_6191524_0 Extracellular solute-binding protein K17321 - - 7e-323 997.0
PYH2_k127_6191524_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 608.0
PYH2_k127_6191524_2 Binding-protein-dependent transport system inner membrane component K17323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 482.0
PYH2_k127_6191524_3 Belongs to the ABC transporter superfamily K17325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 477.0
PYH2_k127_6191524_4 permease K17322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 460.0
PYH2_k127_6191524_5 Belongs to the ABC transporter superfamily K17324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 437.0
PYH2_k127_6191524_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
PYH2_k127_6191524_7 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 288.0
PYH2_k127_6191524_8 small integral membrane protein - - - 0.00000000000000000000000000000001196 130.0
PYH2_k127_6201048_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 393.0
PYH2_k127_6201048_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000008797 237.0
PYH2_k127_6201048_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000001242 199.0
PYH2_k127_6201048_3 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.000001477 56.0
PYH2_k127_6206125_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002521 283.0
PYH2_k127_6206125_1 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000000000001913 137.0
PYH2_k127_6206125_2 Nitroreductase family - - - 0.000000000000000000000000000003875 126.0
PYH2_k127_6206125_3 Arrestin (or S-antigen), C-terminal domain - GO:0003674,GO:0005488,GO:0005515 - 0.00000000004841 74.0
PYH2_k127_6206661_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.157e-200 639.0
PYH2_k127_6206661_1 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 555.0
PYH2_k127_6206661_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000147 259.0
PYH2_k127_6206661_11 ECF transporter, substrate-specific component K16927 - - 0.000000000000000000000000000000000000000000000000000000000001634 220.0
PYH2_k127_6206661_12 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000004567 211.0
PYH2_k127_6206661_13 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000003706 197.0
PYH2_k127_6206661_14 Prenyltransferase and squalene oxidase repeat - - - 0.00000000000000000000000000000000000000000000005428 184.0
PYH2_k127_6206661_15 Gtr1/RagA G protein conserved region K07874 GO:0000003,GO:0000139,GO:0000278,GO:0000280,GO:0000281,GO:0000910,GO:0002790,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005886,GO:0006810,GO:0006888,GO:0006928,GO:0006996,GO:0007017,GO:0007018,GO:0007030,GO:0007049,GO:0007112,GO:0007140,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0007276,GO:0007399,GO:0008088,GO:0008089,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0010256,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010817,GO:0010970,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030334,GO:0030705,GO:0031090,GO:0031344,GO:0031346,GO:0031982,GO:0031984,GO:0032024,GO:0032153,GO:0032154,GO:0032155,GO:0032482,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032940,GO:0033036,GO:0033206,GO:0033365,GO:0033500,GO:0034067,GO:0034613,GO:0035556,GO:0040012,GO:0042175,GO:0042592,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0046883,GO:0046887,GO:0046903,GO:0046907,GO:0048193,GO:0048232,GO:0048285,GO:0048518,GO:0048522,GO:0048609,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0048878,GO:0050708,GO:0050714,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050793,GO:0050794,GO:0050796,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051301,GO:0051321,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0060284,GO:0061640,GO:0065007,GO:0065008,GO:0070201,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0072741,GO:0090087,GO:0090276,GO:0090277,GO:0098588,GO:0098590,GO:0098791,GO:0098827,GO:0098930,GO:0099111,GO:0120035,GO:0140013,GO:1900006,GO:1903046,GO:1903047,GO:1903530,GO:1903532,GO:1904951,GO:1905345,GO:1990778,GO:2000026,GO:2000145 - 0.0000000000000000000000000000000000006054 148.0
PYH2_k127_6206661_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000003884 139.0
PYH2_k127_6206661_17 Yqey-like protein K09117 - - 0.000000000000000000000000000004047 125.0
PYH2_k127_6206661_18 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000004697 111.0
PYH2_k127_6206661_19 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000009032 115.0
PYH2_k127_6206661_2 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 506.0
PYH2_k127_6206661_20 CHRD domain - - - 0.00000000000000000000001749 106.0
PYH2_k127_6206661_21 Ribosome-binding factor A K02834 - - 0.000000000000000000001884 98.0
PYH2_k127_6206661_23 6-phospho-beta-galactosidase activity - - - 0.000000000000000005758 98.0
PYH2_k127_6206661_3 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 509.0
PYH2_k127_6206661_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 475.0
PYH2_k127_6206661_5 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 476.0
PYH2_k127_6206661_6 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 396.0
PYH2_k127_6206661_7 short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 340.0
PYH2_k127_6206661_8 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 336.0
PYH2_k127_6206661_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
PYH2_k127_6236858_0 peptidase activity, acting on L-amino acid peptides K01337,K01400,K20276 - 3.4.21.50,3.4.24.28 1.501e-224 725.0
PYH2_k127_6236858_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 589.0
PYH2_k127_6236858_2 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 417.0
PYH2_k127_6236858_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 346.0
PYH2_k127_6236858_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000006672 239.0
PYH2_k127_6247478_0 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 521.0
PYH2_k127_6247478_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 396.0
PYH2_k127_6247478_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 349.0
PYH2_k127_6247478_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
PYH2_k127_6247478_4 aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 313.0
PYH2_k127_6247478_5 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000003526 148.0
PYH2_k127_6247478_6 Bacterial PH domain - - - 0.000000000000000000000000001462 125.0
PYH2_k127_6260835_0 Sulfatase - - - 1.536e-209 664.0
PYH2_k127_6260835_1 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000000000408 146.0
PYH2_k127_6260835_2 - - - - 0.000000000000000000000000000001441 130.0
PYH2_k127_626247_0 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000003204 192.0
PYH2_k127_626247_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000002959 183.0
PYH2_k127_626247_2 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000006492 179.0
PYH2_k127_6270885_0 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 598.0
PYH2_k127_6270885_1 ISPsy14, transposition helper protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001035 250.0
PYH2_k127_6276828_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0 1743.0
PYH2_k127_6309725_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003458 282.0
PYH2_k127_6309725_1 ROK family K00845 - 2.7.1.2 0.0003507 45.0
PYH2_k127_6309763_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
PYH2_k127_6309763_1 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000001171 192.0
PYH2_k127_6309763_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000002526 86.0
PYH2_k127_6309763_3 COG1063 Threonine dehydrogenase and related Zn-dependent K00008,K00060 - 1.1.1.103,1.1.1.14 0.0001727 48.0
PYH2_k127_6319404_0 Belongs to the ClpA ClpB family K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1064.0
PYH2_k127_6319404_1 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1030.0
PYH2_k127_6319404_2 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 1.854e-293 914.0
PYH2_k127_6319404_3 PIN domain - - - 0.00000000000000000000000000000008121 129.0
PYH2_k127_6319404_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000003254 103.0
PYH2_k127_6319404_5 toxin-antitoxin pair type II binding - - - 0.00000000000000005824 83.0
PYH2_k127_6319404_6 Rho guanyl-nucleotide exchange factor activity K07532,K12331 GO:0000003,GO:0000902,GO:0000904,GO:0001505,GO:0001558,GO:0001664,GO:0001700,GO:0001703,GO:0002009,GO:0002064,GO:0002165,GO:0003006,GO:0003008,GO:0003012,GO:0003381,GO:0003382,GO:0003383,GO:0003384,GO:0003674,GO:0005085,GO:0005088,GO:0005089,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005826,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006355,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007163,GO:0007165,GO:0007186,GO:0007264,GO:0007265,GO:0007266,GO:0007275,GO:0007276,GO:0007277,GO:0007349,GO:0007369,GO:0007370,GO:0007374,GO:0007375,GO:0007377,GO:0007399,GO:0007424,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008360,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009826,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010004,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010769,GO:0010941,GO:0010942,GO:0010975,GO:0015629,GO:0016020,GO:0016043,GO:0016049,GO:0016324,GO:0016328,GO:0016331,GO:0016476,GO:0017016,GO:0017048,GO:0019219,GO:0019222,GO:0019899,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023056,GO:0030010,GO:0030029,GO:0030036,GO:0030048,GO:0030154,GO:0030478,GO:0030588,GO:0030589,GO:0030855,GO:0030863,GO:0030864,GO:0031267,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031532,GO:0032153,GO:0032155,GO:0032501,GO:0032502,GO:0032504,GO:0032956,GO:0032970,GO:0032989,GO:0033043,GO:0035023,GO:0035025,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035277,GO:0035295,GO:0035556,GO:0040007,GO:0040008,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043519,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045177,GO:0045178,GO:0045179,GO:0045595,GO:0045664,GO:0045893,GO:0045935,GO:0045995,GO:0046578,GO:0046579,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048589,GO:0048598,GO:0048609,GO:0048646,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0050767,GO:0050770,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051020,GO:0051056,GO:0051057,GO:0051128,GO:0051171,GO:0051173,GO:0051239,GO:0051252,GO:0051254,GO:0051493,GO:0051704,GO:0051716,GO:0051960,GO:0060255,GO:0060284,GO:0060429,GO:0060541,GO:0060560,GO:0060562,GO:0060571,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070938,GO:0071840,GO:0071944,GO:0080090,GO:0090254,GO:0097435,GO:0098590,GO:0098772,GO:0099568,GO:0099738,GO:0120035,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:2000026,GO:2000112,GO:2001141 - 0.0009201 45.0
PYH2_k127_6353808_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 587.0
PYH2_k127_6353808_1 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000001419 269.0
PYH2_k127_6353808_2 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004482 241.0
PYH2_k127_6353808_3 DDE superfamily endonuclease - - - 0.00000000000006973 72.0
PYH2_k127_6353808_4 CobW/HypB/UreG, nucleotide-binding domain - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0008715 51.0
PYH2_k127_6372370_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 525.0
PYH2_k127_6372370_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000003097 100.0
PYH2_k127_6378697_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 3.345e-213 712.0
PYH2_k127_6378697_1 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000002649 209.0
PYH2_k127_6378697_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000001619 128.0
PYH2_k127_6378697_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000001768 88.0
PYH2_k127_6393499_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 301.0
PYH2_k127_6393499_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000001988 189.0
PYH2_k127_6393499_2 positive regulation of growth K19687 - - 0.000000000000000000000000001293 122.0
PYH2_k127_6393499_3 - - - - 0.000000000000000000000341 108.0
PYH2_k127_6395972_0 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 458.0
PYH2_k127_6395972_1 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000009568 151.0
PYH2_k127_6395972_2 Methyltransferase domain - - - 0.0000000000000001544 83.0
PYH2_k127_6399039_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.402e-246 782.0
PYH2_k127_6399039_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.103e-227 716.0
PYH2_k127_6399039_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000003533 210.0
PYH2_k127_6399039_11 - - - - 0.000000000000000000000000000000000000001972 154.0
PYH2_k127_6399039_12 NUDIX domain - - - 0.0000000000000000000000000000000002682 138.0
PYH2_k127_6399039_13 MazG-like family - - - 0.00000000000000000000000000000001504 129.0
PYH2_k127_6399039_14 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000005237 126.0
PYH2_k127_6399039_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000005784 119.0
PYH2_k127_6399039_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.397e-223 702.0
PYH2_k127_6399039_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 9.662e-197 620.0
PYH2_k127_6399039_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 359.0
PYH2_k127_6399039_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 329.0
PYH2_k127_6399039_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 312.0
PYH2_k127_6399039_7 DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007136 256.0
PYH2_k127_6399039_8 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000000000000009712 234.0
PYH2_k127_6399039_9 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000001693 205.0
PYH2_k127_6400788_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 2.557e-206 655.0
PYH2_k127_6400788_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 507.0
PYH2_k127_6400788_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000001967 121.0
PYH2_k127_6400788_11 PFAM regulatory protein GntR HTH K07979 - - 0.000000000000000000000000000505 118.0
PYH2_k127_6400788_12 PFAM CBS domain K03699 - - 0.0000000000000000000001256 99.0
PYH2_k127_6400788_13 - - - - 0.00000000000000002964 89.0
PYH2_k127_6400788_14 - - - - 0.00000000000000009397 91.0
PYH2_k127_6400788_15 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0004207 45.0
PYH2_k127_6400788_2 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 413.0
PYH2_k127_6400788_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 346.0
PYH2_k127_6400788_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003 262.0
PYH2_k127_6400788_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000181 254.0
PYH2_k127_6400788_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000004103 243.0
PYH2_k127_6400788_7 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000002926 172.0
PYH2_k127_6400788_8 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000008147 172.0
PYH2_k127_6400788_9 Putative regulatory protein - - - 0.000000000000000000000000000004675 124.0
PYH2_k127_6415407_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 5.189e-304 951.0
PYH2_k127_6415407_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 508.0
PYH2_k127_6415407_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 335.0
PYH2_k127_6415407_3 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 310.0
PYH2_k127_6415407_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003683 228.0
PYH2_k127_6415407_5 belongs to the thioredoxin family K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000000001103 216.0
PYH2_k127_6415407_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000003484 56.0
PYH2_k127_6489092_0 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 542.0
PYH2_k127_6489092_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 535.0
PYH2_k127_6489092_10 Domain of unknown function (DUF4872) - - - 0.0000000000000000000000000000000008647 145.0
PYH2_k127_6489092_11 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000002125 128.0
PYH2_k127_6489092_12 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000575 119.0
PYH2_k127_6489092_13 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000001154 112.0
PYH2_k127_6489092_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000002206 113.0
PYH2_k127_6489092_15 - - - - 0.00000000006788 66.0
PYH2_k127_6489092_2 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 509.0
PYH2_k127_6489092_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000004719 251.0
PYH2_k127_6489092_4 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
PYH2_k127_6489092_5 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000003859 217.0
PYH2_k127_6489092_6 DinB family K18843 - - 0.000000000000000000000000000000000000000000000000000000001857 207.0
PYH2_k127_6489092_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000969 163.0
PYH2_k127_6489092_8 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.00000000000000000000000000000000000000676 157.0
PYH2_k127_6489092_9 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000000000000001324 150.0
PYH2_k127_6542102_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004881 295.0
PYH2_k127_6542102_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001024 211.0
PYH2_k127_6567718_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 381.0
PYH2_k127_6567718_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006644 276.0
PYH2_k127_6600456_0 PFAM Transketolase central region K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 451.0
PYH2_k127_6600456_1 catalytic domain of components of various dehydrogenase complexes K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 380.0
PYH2_k127_6600456_2 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000004812 171.0
PYH2_k127_6600456_3 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0001233 46.0
PYH2_k127_6601566_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 514.0
PYH2_k127_6601566_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 448.0
PYH2_k127_6601566_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 435.0
PYH2_k127_6601566_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 421.0
PYH2_k127_6601566_4 Belongs to the SEDS family K02563,K03588 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 296.0
PYH2_k127_6601566_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 291.0
PYH2_k127_6601566_6 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000006394 268.0
PYH2_k127_6601566_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000001219 197.0
PYH2_k127_6601566_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000001516 195.0
PYH2_k127_6601566_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000008635 87.0
PYH2_k127_6617716_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 316.0
PYH2_k127_6617716_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 313.0
PYH2_k127_6617716_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000004649 203.0
PYH2_k127_6617716_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000004465 145.0
PYH2_k127_6617716_4 PFAM HlyD family secretion protein K01993 - - 0.000001024 59.0
PYH2_k127_6650689_0 Tagatose 6 phosphate kinase K16371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 555.0
PYH2_k127_6650689_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000002784 184.0
PYH2_k127_6650689_2 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000018 167.0
PYH2_k127_6650689_3 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000005246 134.0
PYH2_k127_6650689_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000212 120.0
PYH2_k127_6650689_5 - - - - 0.000000002264 66.0
PYH2_k127_6676228_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 472.0
PYH2_k127_6676228_1 PFAM Cytochrome P450 - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 460.0
PYH2_k127_6676228_10 NAD-dependent epimerase dehydratase K07071 - - 0.0000004386 55.0
PYH2_k127_6676228_2 Lycopene cyclase protein K06443 - 5.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 432.0
PYH2_k127_6676228_3 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 426.0
PYH2_k127_6676228_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 377.0
PYH2_k127_6676228_5 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 379.0
PYH2_k127_6676228_6 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 322.0
PYH2_k127_6676228_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000002831 176.0
PYH2_k127_6676228_8 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000008672 169.0
PYH2_k127_6676228_9 - - - - 0.00000000001116 78.0
PYH2_k127_6707986_0 multi-organism process K12063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 569.0
PYH2_k127_6707986_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004326 241.0
PYH2_k127_6707986_3 - - - - 0.0000000000000000000000000000000000000000000000004582 186.0
PYH2_k127_6709783_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.5e-323 1015.0
PYH2_k127_6709783_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.026e-228 722.0
PYH2_k127_6709783_2 PhoQ Sensor - - - 0.0000000000000000000000000000000002451 147.0
PYH2_k127_6709783_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000001255 110.0
PYH2_k127_6709783_4 Histidine kinase - - - 0.00000000000000000000000897 105.0
PYH2_k127_6709783_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000001126 84.0
PYH2_k127_6716229_0 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 331.0
PYH2_k127_6716229_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 304.0
PYH2_k127_6716229_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.000000000000000000000000000000000001905 145.0
PYH2_k127_6716229_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000001083 113.0
PYH2_k127_6716229_4 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000004203 81.0
PYH2_k127_6721266_0 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004343 267.0
PYH2_k127_6721266_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
PYH2_k127_6721266_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000003746 203.0
PYH2_k127_6721266_3 cytochrome c biogenesis protein K07399 - - 0.0001479 54.0
PYH2_k127_6731619_0 PFAM ABC transporter transmembrane region K06147 - - 2.688e-252 795.0
PYH2_k127_6731619_1 PFAM ABC transporter transmembrane region K06147 - - 1.48e-250 798.0
PYH2_k127_6731619_2 ABC transporter K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 331.0
PYH2_k127_6731619_3 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000008329 199.0
PYH2_k127_6731619_4 - - - - 0.000000000000000000000000000000000000000000575 166.0
PYH2_k127_6731619_5 Cupin domain - - - 0.0000000000000000000000000000005087 124.0
PYH2_k127_6731619_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000001891 114.0
PYH2_k127_6731619_7 PFAM regulatory protein TetR - - - 0.000000000000002903 83.0
PYH2_k127_6731619_8 - - - - 0.00000000000001639 78.0
PYH2_k127_6744920_0 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 422.0
PYH2_k127_6744920_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000001156 245.0
PYH2_k127_6744920_2 SPTR B7KVZ8 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000001835 195.0
PYH2_k127_6744920_3 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000000000000000000004735 198.0
PYH2_k127_6744920_4 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000009288 182.0
PYH2_k127_6744920_5 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000003413 165.0
PYH2_k127_6744920_6 Protein of unknown function (DUF1475) - - - 0.0000000000000000000000000000006795 128.0
PYH2_k127_6744920_7 Phospholipid methyltransferase - - - 0.00000000006862 70.0
PYH2_k127_6744920_8 Pfam:Methyltransf_26 - - - 0.0000000001515 66.0
PYH2_k127_6758802_0 permease K07089 - - 1.2e-212 669.0
PYH2_k127_6758802_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002058 274.0
PYH2_k127_6758802_2 - - - - 0.000000000000000000000000000000000000000002909 160.0
PYH2_k127_6758802_3 Thioredoxin domain - - - 0.000000000000000000000000000000000003758 138.0
PYH2_k127_6791306_0 PFAM acyl-CoA dehydrogenase domain protein K00249,K11731 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
PYH2_k127_6791306_1 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 308.0
PYH2_k127_6791306_2 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 291.0
PYH2_k127_6791306_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000001674 233.0
PYH2_k127_6791306_4 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000002974 174.0
PYH2_k127_6791306_5 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000001104 109.0
PYH2_k127_6791306_6 23S rRNA-intervening sequence protein - - - 0.000000000000000000003788 97.0
PYH2_k127_6794147_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1092.0
PYH2_k127_6794147_1 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
PYH2_k127_6794147_2 - - - - 0.00000000000000000000000000004603 120.0
PYH2_k127_6813416_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.715e-240 766.0
PYH2_k127_6813416_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 1.245e-211 668.0
PYH2_k127_6813416_10 spore germination K03605 - - 0.00000000000000000000000002693 117.0
PYH2_k127_6813416_11 Multisubunit Na H antiporter MnhC subunit K00340,K05567 - 1.6.5.3 0.0000000000000000000000004888 110.0
PYH2_k127_6813416_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000003067 83.0
PYH2_k127_6813416_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 387.0
PYH2_k127_6813416_3 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 336.0
PYH2_k127_6813416_4 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001919 277.0
PYH2_k127_6813416_5 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000007056 212.0
PYH2_k127_6813416_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000007959 196.0
PYH2_k127_6813416_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000006137 154.0
PYH2_k127_6813416_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000006542 147.0
PYH2_k127_6813416_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000001831 144.0
PYH2_k127_6818568_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.478e-232 723.0
PYH2_k127_6818568_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 572.0
PYH2_k127_6818568_10 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000005247 220.0
PYH2_k127_6818568_11 Lysin motif - - - 0.000000000000000000000000000000000000000000000000007349 193.0
PYH2_k127_6818568_12 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000001417 190.0
PYH2_k127_6818568_13 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000004464 153.0
PYH2_k127_6818568_14 - - - - 0.000000000000000000000000000000009974 145.0
PYH2_k127_6818568_15 succinate dehydrogenase K00241 - - 0.0000000000000000000000772 109.0
PYH2_k127_6818568_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000003872 91.0
PYH2_k127_6818568_17 succinate dehydrogenase K00242 - - 0.000000000000007697 85.0
PYH2_k127_6818568_2 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 553.0
PYH2_k127_6818568_3 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 450.0
PYH2_k127_6818568_4 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 337.0
PYH2_k127_6818568_5 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 349.0
PYH2_k127_6818568_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 315.0
PYH2_k127_6818568_7 Spermine/spermidine synthase domain K06983,K15984 - 2.1.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 315.0
PYH2_k127_6818568_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000205 280.0
PYH2_k127_6818568_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000002192 272.0
PYH2_k127_6848050_0 peptidase activity - - - 0.000000000000000000000000001379 128.0
PYH2_k127_6858682_0 Domain of unknown function (DUF4070) - - - 1.802e-223 705.0
PYH2_k127_6858682_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 395.0
PYH2_k127_6858682_2 - - - - 0.0000000000000000002222 99.0
PYH2_k127_690398_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 462.0
PYH2_k127_690398_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 443.0
PYH2_k127_690398_2 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 405.0
PYH2_k127_690398_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 266.0
PYH2_k127_690398_4 PFAM transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000001595 160.0
PYH2_k127_69863_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.661e-304 955.0
PYH2_k127_69863_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.415e-268 835.0
PYH2_k127_69863_10 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
PYH2_k127_69863_11 ABC transporter (Permease) K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000058 285.0
PYH2_k127_69863_12 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003317 258.0
PYH2_k127_69863_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000287 247.0
PYH2_k127_69863_14 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000008029 231.0
PYH2_k127_69863_15 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002495 222.0
PYH2_k127_69863_16 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000001838 213.0
PYH2_k127_69863_17 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000001108 194.0
PYH2_k127_69863_18 TIGRFAM phosphonate ABC transporter, inner membrane subunit K02042 - - 0.00000000000000000000000000000000000000000000000003905 203.0
PYH2_k127_69863_19 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000002541 177.0
PYH2_k127_69863_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.851e-265 825.0
PYH2_k127_69863_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.000000000000002905 77.0
PYH2_k127_69863_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00002388 57.0
PYH2_k127_69863_3 ABC transporter K06147,K11085 - - 5.123e-214 687.0
PYH2_k127_69863_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 521.0
PYH2_k127_69863_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 386.0
PYH2_k127_69863_6 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 368.0
PYH2_k127_69863_7 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 342.0
PYH2_k127_69863_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 297.0
PYH2_k127_69863_9 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000036 291.0
PYH2_k127_6988525_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001586 173.0
PYH2_k127_6988525_1 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000003386 163.0
PYH2_k127_6988525_2 - - - - 0.000000000005334 71.0
PYH2_k127_6988525_3 - - - - 0.0001147 53.0
PYH2_k127_7003446_0 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000003946 214.0
PYH2_k127_7003446_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000576 109.0
PYH2_k127_7003446_2 Tetratricopeptide repeats - - - 0.000000000000000001469 94.0
PYH2_k127_7003446_3 - - - - 0.0000000001975 72.0
PYH2_k127_7009652_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000001164 130.0
PYH2_k127_7009652_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000007998 78.0
PYH2_k127_7009652_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000002383 77.0
PYH2_k127_7009652_3 - - - - 0.00000001143 68.0
PYH2_k127_7009652_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001303 65.0
PYH2_k127_7009652_5 - - - - 0.0002965 54.0
PYH2_k127_7047328_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 399.0
PYH2_k127_7047328_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 385.0
PYH2_k127_7047328_2 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 345.0
PYH2_k127_7047328_3 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 321.0
PYH2_k127_7047328_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000005865 160.0
PYH2_k127_7074206_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 477.0
PYH2_k127_7074206_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 436.0
PYH2_k127_7074206_2 TIGRFAM phosphate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 426.0
PYH2_k127_7074206_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 421.0
PYH2_k127_7074206_4 Two component transcriptional regulator, winged helix family K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000381 282.0
PYH2_k127_7074206_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001109 250.0
PYH2_k127_7074206_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000004313 199.0
PYH2_k127_7074206_7 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000003656 184.0
PYH2_k127_7121732_0 SMART Elongator protein 3 MiaB NifB - - - 1.493e-228 725.0
PYH2_k127_7121732_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 602.0
PYH2_k127_7121732_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 519.0
PYH2_k127_7121732_3 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 413.0
PYH2_k127_7121732_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 344.0
PYH2_k127_7121732_5 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 315.0
PYH2_k127_7121732_6 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000192 239.0
PYH2_k127_7121732_7 Nucleotidyl transferase K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000006348 207.0
PYH2_k127_7121732_8 Calx-beta domain - - - 0.000000000000000000000000000000000002091 143.0
PYH2_k127_7121732_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000003056 60.0
PYH2_k127_7123423_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 492.0
PYH2_k127_7123423_1 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 428.0
PYH2_k127_7123423_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 306.0
PYH2_k127_7152319_0 Metallo-beta-lactamase superfamily domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 514.0
PYH2_k127_7152319_1 Protein of unknown function (DUF4058) - - - 0.000000000000000000000000000000000000000000000000000000000001285 221.0
PYH2_k127_7152319_2 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000001396 91.0
PYH2_k127_7152319_3 RecQ zinc-binding K03654 - 3.6.4.12 0.00000001037 59.0
PYH2_k127_7165932_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.57e-322 1017.0
PYH2_k127_7165932_1 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000007671 154.0
PYH2_k127_7165932_2 Alpha beta hydrolase fold - - - 0.00000000003129 70.0
PYH2_k127_7174819_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 372.0
PYH2_k127_7174819_1 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000006024 190.0
PYH2_k127_7174819_2 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000009866 183.0
PYH2_k127_7174819_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000002301 174.0
PYH2_k127_7176532_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.326e-210 669.0
PYH2_k127_7176532_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 597.0
PYH2_k127_7176532_10 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 312.0
PYH2_k127_7176532_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 310.0
PYH2_k127_7176532_12 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003844 242.0
PYH2_k127_7176532_13 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000009155 238.0
PYH2_k127_7176532_14 Acetyltransferase (GNAT) domain K22479 - - 0.00000000000000000000000000000000000000000000000000000000000002417 220.0
PYH2_k127_7176532_15 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000002326 210.0
PYH2_k127_7176532_16 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000003874 175.0
PYH2_k127_7176532_17 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000002167 164.0
PYH2_k127_7176532_18 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000006939 149.0
PYH2_k127_7176532_19 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000003203 146.0
PYH2_k127_7176532_2 Polysaccharide biosynthesis protein K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 513.0
PYH2_k127_7176532_20 Male sterility protein K00091 - 1.1.1.219 0.00000000000000000000000000000000002752 151.0
PYH2_k127_7176532_21 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000000000008644 135.0
PYH2_k127_7176532_22 - - - - 0.000000000000000000000000008287 118.0
PYH2_k127_7176532_23 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000006731 111.0
PYH2_k127_7176532_24 - - - - 0.00000000000000000000009534 107.0
PYH2_k127_7176532_25 nuclease activity K06218 - - 0.0000000000000000002129 90.0
PYH2_k127_7176532_27 - - - - 0.00000000000241 72.0
PYH2_k127_7176532_28 Pentapeptide repeats (8 copies) - - - 0.000000000004459 72.0
PYH2_k127_7176532_29 SPFH domain-Band 7 family - - - 0.00000000001376 66.0
PYH2_k127_7176532_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 443.0
PYH2_k127_7176532_31 YtxH-like protein - - - 0.000000001312 64.0
PYH2_k127_7176532_32 Zinc finger domain - - - 0.000000002103 70.0
PYH2_k127_7176532_33 - - - - 0.000000003017 59.0
PYH2_k127_7176532_34 - - - - 0.00000003714 66.0
PYH2_k127_7176532_35 TIGRFAM Polymorphic membrane protein, Chlamydia - - - 0.0000003049 63.0
PYH2_k127_7176532_36 AraC-like ligand binding domain - - - 0.00001903 49.0
PYH2_k127_7176532_37 Transcription factor zinc-finger - - - 0.00008839 55.0
PYH2_k127_7176532_38 ThiS family - - - 0.0002804 50.0
PYH2_k127_7176532_4 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 448.0
PYH2_k127_7176532_5 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 412.0
PYH2_k127_7176532_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 399.0
PYH2_k127_7176532_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 398.0
PYH2_k127_7176532_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 400.0
PYH2_k127_7176532_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 379.0
PYH2_k127_7184775_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 409.0
PYH2_k127_7184775_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
PYH2_k127_7184775_2 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001881 251.0
PYH2_k127_7184775_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0001028 47.0
PYH2_k127_7199271_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000004435 127.0
PYH2_k127_7199271_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position - - - 0.0000000000000000000000000000558 131.0
PYH2_k127_7199271_2 PFAM OmpA MotB domain protein - - - 0.000000000001244 76.0
PYH2_k127_7199271_3 alpha amylase, catalytic region - - - 0.00000000001376 66.0
PYH2_k127_7199271_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.00000000003419 66.0
PYH2_k127_7199271_5 Meiotic cell cortex C-terminal pleckstrin homology K17978 GO:0000001,GO:0000003,GO:0000226,GO:0000266,GO:0000280,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005856,GO:0005938,GO:0006810,GO:0006928,GO:0006996,GO:0007005,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007127,GO:0008092,GO:0008104,GO:0008150,GO:0009987,GO:0010970,GO:0015630,GO:0015631,GO:0016043,GO:0022402,GO:0022414,GO:0030473,GO:0030705,GO:0030863,GO:0030981,GO:0030989,GO:0032065,GO:0032507,GO:0033036,GO:0034613,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043495,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045185,GO:0046907,GO:0048285,GO:0048308,GO:0048311,GO:0051012,GO:0051179,GO:0051234,GO:0051235,GO:0051321,GO:0051640,GO:0051641,GO:0051646,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0061982,GO:0065007,GO:0065008,GO:0070727,GO:0071840,GO:0071944,GO:0072384,GO:0099111,GO:0099568,GO:0140013,GO:1903046 - 0.000006344 58.0
PYH2_k127_7216059_0 Belongs to the peptidase S16 family - - - 4.339e-207 671.0
PYH2_k127_7216059_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 403.0
PYH2_k127_7216059_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002854 283.0
PYH2_k127_7216059_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000116 208.0
PYH2_k127_7216059_4 Protein of unknown function (DUF1706) - - - 0.000000000000000000000000000000000000000000000002629 177.0
PYH2_k127_7216059_5 LysM domain K12204 - - 0.00000000000000000000000001625 123.0
PYH2_k127_7216059_6 Protease prsW family - - - 0.000002843 59.0
PYH2_k127_7222973_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.694e-228 734.0
PYH2_k127_7222973_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.086e-207 661.0
PYH2_k127_7222973_10 - - - - 0.000000000000000000000000000000002914 134.0
PYH2_k127_7222973_11 capsule polysaccharide biosynthetic process K16692 - - 0.0000000000000000000000000001196 123.0
PYH2_k127_7222973_12 PFAM 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000002309 96.0
PYH2_k127_7222973_13 Cold-shock protein K03704 - - 0.000000000000000003357 87.0
PYH2_k127_7222973_14 Transporter associated domain - - - 0.00000000000000003361 83.0
PYH2_k127_7222973_15 Methyltransferase domain - - - 0.00000000000002319 81.0
PYH2_k127_7222973_16 Lipopolysaccharide biosynthesis protein - - - 0.000000006154 58.0
PYH2_k127_7222973_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 539.0
PYH2_k127_7222973_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 422.0
PYH2_k127_7222973_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 330.0
PYH2_k127_7222973_5 TIGRFAM capsular exopolysaccharide family K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000109 280.0
PYH2_k127_7222973_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002168 243.0
PYH2_k127_7222973_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000001415 186.0
PYH2_k127_7222973_8 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000407 149.0
PYH2_k127_7222973_9 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000001248 141.0
PYH2_k127_7240218_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 316.0
PYH2_k127_7240218_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000002062 104.0
PYH2_k127_7245223_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 9.337e-229 740.0
PYH2_k127_7245223_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 571.0
PYH2_k127_7245223_11 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000003231 213.0
PYH2_k127_7245223_12 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.0000000000000000000000000000000000000000000000000000977 195.0
PYH2_k127_7245223_13 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
PYH2_k127_7245223_14 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000004353 179.0
PYH2_k127_7245223_16 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000003607 112.0
PYH2_k127_7245223_17 serine-type peptidase activity - - - 0.0000000000000000037 90.0
PYH2_k127_7245223_19 Domain of unknown function DUF11 - - - 0.000004945 58.0
PYH2_k127_7245223_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 526.0
PYH2_k127_7245223_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 502.0
PYH2_k127_7245223_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 463.0
PYH2_k127_7245223_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 391.0
PYH2_k127_7245223_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 373.0
PYH2_k127_7245223_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 349.0
PYH2_k127_7245223_8 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 363.0
PYH2_k127_7245223_9 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000003898 230.0
PYH2_k127_7260904_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 2.437e-235 739.0
PYH2_k127_7260904_1 Alpha beta hydrolase K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 488.0
PYH2_k127_7260904_2 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 360.0
PYH2_k127_7260904_3 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000005059 156.0
PYH2_k127_7260904_4 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.000000000000000000000001039 108.0
PYH2_k127_7260904_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000002415 73.0
PYH2_k127_7260904_6 His Kinase A (phosphoacceptor) domain - - - 0.0000003311 63.0
PYH2_k127_7271334_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 319.0
PYH2_k127_7271334_1 PFAM transposase, IS4 family protein - - - 0.000003296 50.0
PYH2_k127_7281639_0 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 548.0
PYH2_k127_7281639_1 Multidrug ABC transporter ATP-binding protein K06158 - - 0.000000000000000000000000000000000000000000000000004753 192.0
PYH2_k127_7281639_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000000000000000000000000001102 189.0
PYH2_k127_7294501_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 353.0
PYH2_k127_7294501_1 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000002819 233.0
PYH2_k127_7323796_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000003347 195.0
PYH2_k127_7323796_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000001791 132.0
PYH2_k127_7323796_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000002484 109.0
PYH2_k127_7323796_3 Lysin motif - - - 0.0000000007474 70.0
PYH2_k127_7331969_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 567.0
PYH2_k127_7331969_1 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 411.0
PYH2_k127_7331969_2 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 403.0
PYH2_k127_7331969_3 ABC-type sugar transport system, permease component K02026,K17323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 419.0
PYH2_k127_7331969_4 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.00000000000000000000000003359 125.0
PYH2_k127_7380629_0 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 353.0
PYH2_k127_7380629_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 302.0
PYH2_k127_7380629_2 PFAM PfkB domain protein K16328 - 2.7.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 284.0
PYH2_k127_7380629_3 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003464 269.0
PYH2_k127_7380629_4 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002809 265.0
PYH2_k127_7380629_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000007216 181.0
PYH2_k127_7380629_6 aminopeptidase - - - 0.00000000000000000000000000000000000006734 158.0
PYH2_k127_7380629_7 response regulator receiver - - - 0.000000000000000000000000000000000007201 152.0
PYH2_k127_7380629_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000007342 99.0
PYH2_k127_7380629_9 8-amino-7-oxononanoate synthase activity - - - 0.00000000000000001343 96.0
PYH2_k127_7397685_0 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 452.0
PYH2_k127_7397685_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000003399 97.0
PYH2_k127_7400545_0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000003388 181.0
PYH2_k127_7400545_1 competence protein - - - 0.000000000000000000000000000000000006431 143.0
PYH2_k127_7400545_2 GTP binding - - - 0.000001334 57.0
PYH2_k127_7435760_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000005618 222.0
PYH2_k127_7435760_1 - - - - 0.000000000000000000000000000000000000000000000000000000007397 207.0
PYH2_k127_7435760_2 Protein of unknown function (DUF971) - - - 0.0000000000000004877 81.0
PYH2_k127_7448397_0 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 454.0
PYH2_k127_7478995_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 406.0
PYH2_k127_7478995_1 DNA binding - - - 0.000000000000000001214 92.0
PYH2_k127_7486983_0 pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 1.827e-220 712.0
PYH2_k127_7486983_1 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 383.0
PYH2_k127_7486983_10 COG2208 Serine phosphatase RsbU, regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000001706 150.0
PYH2_k127_7486983_11 GAF domain - - - 0.0000000000000000000000000008555 132.0
PYH2_k127_7486983_12 - K01992 - - 0.00000000000000000000000003781 118.0
PYH2_k127_7486983_13 response regulator K07689 - - 0.00000000000000000000001755 104.0
PYH2_k127_7486983_14 - - - - 0.0000000000001835 74.0
PYH2_k127_7486983_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 366.0
PYH2_k127_7486983_3 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 327.0
PYH2_k127_7486983_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001822 264.0
PYH2_k127_7486983_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002711 285.0
PYH2_k127_7486983_6 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000124 158.0
PYH2_k127_7486983_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000279 156.0
PYH2_k127_7486983_8 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000002232 140.0
PYH2_k127_7486983_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000596 143.0
PYH2_k127_7503192_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.677e-310 979.0
PYH2_k127_7503192_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 351.0
PYH2_k127_7503192_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000008958 242.0
PYH2_k127_7503192_3 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000002444 168.0
PYH2_k127_7503192_4 23S rRNA-intervening sequence protein - - - 0.000000000000000000005054 97.0
PYH2_k127_7503192_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000001095 96.0
PYH2_k127_7503192_6 PFAM Forkhead-associated protein - - - 0.000000000000000001888 91.0
PYH2_k127_7508430_0 Polysaccharide biosynthesis protein - - - 7.842e-209 684.0
PYH2_k127_7508430_1 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 7.816e-201 634.0
PYH2_k127_7508430_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 298.0
PYH2_k127_7508430_3 PFAM extracellular solute-binding protein family 1 K10232 - - 0.0000000000000000000000000000000000000000000000000000007312 209.0
PYH2_k127_7508430_4 Periplasmic binding protein LacI transcriptional regulator K01775,K02529,K05499 - 5.1.1.1 0.0000000000000000005243 94.0
PYH2_k127_7508430_5 PFAM regulatory protein LacI - - - 0.0000000000002922 72.0
PYH2_k127_7508430_6 glycerophosphodiester transmembrane transport K02026,K10234 - - 0.000000005593 66.0
PYH2_k127_7521129_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
PYH2_k127_7521129_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000004322 176.0
PYH2_k127_7521129_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000004703 129.0
PYH2_k127_7523481_0 Resolvase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 492.0
PYH2_k127_7523481_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000005132 223.0
PYH2_k127_7523481_2 - - - - 0.00000000000000000000000000000000000000000000004284 171.0
PYH2_k127_7523481_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000003194 110.0
PYH2_k127_7523481_4 - - - - 0.0000000000000000006543 89.0
PYH2_k127_7523687_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 595.0
PYH2_k127_7523687_1 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.0000000000000000000000000000000000000993 160.0
PYH2_k127_7523687_2 PFAM basic membrane lipoprotein K07335 - - 0.0000000000000000000000000001232 121.0
PYH2_k127_7523687_3 Forkhead associated domain - - - 0.00000006509 60.0
PYH2_k127_752428_0 Elongator protein 3, MiaB family, Radical SAM - - - 6.297e-202 640.0
PYH2_k127_752428_1 cellulase activity K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000001203 263.0
PYH2_k127_7557187_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 393.0
PYH2_k127_7579462_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1124.0
PYH2_k127_7579462_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.82e-305 949.0
PYH2_k127_7579462_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000418 49.0
PYH2_k127_7579462_11 Fibronectin type 3 domain - - - 0.000009877 54.0
PYH2_k127_7579462_12 Domain of unknown function (DUF4124) - - - 0.00001511 54.0
PYH2_k127_7579462_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001032 170.0
PYH2_k127_7579462_3 membrane - - - 0.00000000000000000000000000000001247 129.0
PYH2_k127_7579462_5 - - - - 0.00000000000000000000000000006603 124.0
PYH2_k127_7579462_6 - - - - 0.000000000000000536 83.0
PYH2_k127_7579462_7 polysaccharide catabolic process K02388,K02396 - - 0.0000000000004297 80.0
PYH2_k127_7579462_8 - - - - 0.000000000003076 72.0
PYH2_k127_7579462_9 Nuclease (SNase domain protein) - - - 0.000000005786 59.0
PYH2_k127_7595757_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 473.0
PYH2_k127_7595757_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 445.0
PYH2_k127_7595757_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 310.0
PYH2_k127_7595757_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 312.0
PYH2_k127_7595757_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133,5.1.3.13,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 295.0
PYH2_k127_7600010_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 2.178e-227 719.0
PYH2_k127_7600010_1 PFAM magnesium chelatase ChlI subunit K07391 - - 3.259e-198 628.0
PYH2_k127_7600010_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 450.0
PYH2_k127_7600010_3 regulation of translation K03530 - - 0.000000000000000000000000000001574 123.0
PYH2_k127_7600010_4 Iron-sulfur cluster loop - - - 0.0000000001681 72.0
PYH2_k127_7643741_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 563.0
PYH2_k127_7643741_1 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 402.0
PYH2_k127_7643741_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003104 248.0
PYH2_k127_7643741_3 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001922 239.0
PYH2_k127_7643741_4 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000002478 233.0
PYH2_k127_7643741_5 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000004799 220.0
PYH2_k127_7643741_6 extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000008962 131.0
PYH2_k127_7643741_7 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000001005 93.0
PYH2_k127_7643741_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.00000000000001589 76.0
PYH2_k127_7643741_9 Beta-lactamase K01286 - 3.4.16.4 0.00000000002922 67.0
PYH2_k127_7650327_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 297.0
PYH2_k127_7650327_1 folic acid synthesis protein K13939,K13941 GO:0003674,GO:0003824,GO:0003848,GO:0004150,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016772,GO:0016778,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019752,GO:0031967,GO:0031975,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000000000005184 198.0
PYH2_k127_7650327_2 PFAM Calcium calmodulin dependent protein kinase II - - - 0.00000000000000000000000000000000000000000000000756 177.0
PYH2_k127_7652305_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 1.522e-227 715.0
PYH2_k127_7652305_1 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 1.792e-223 702.0
PYH2_k127_7652305_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
PYH2_k127_7652305_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000004451 242.0
PYH2_k127_7652305_12 COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000001123 227.0
PYH2_k127_7652305_13 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.00000000000000000000000000000000000000000000000000000000001854 211.0
PYH2_k127_7652305_14 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000002838 214.0
PYH2_k127_7652305_15 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000005126 184.0
PYH2_k127_7652305_16 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000003073 171.0
PYH2_k127_7652305_17 beta-lactamase domain protein - - - 0.000000000000000000000000000000000005204 146.0
PYH2_k127_7652305_18 - - - - 0.000000000000005964 82.0
PYH2_k127_7652305_19 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000002231 86.0
PYH2_k127_7652305_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 2.245e-217 685.0
PYH2_k127_7652305_20 - - - - 0.00001653 53.0
PYH2_k127_7652305_21 Belongs to the Nudix hydrolase family - - - 0.0007844 42.0
PYH2_k127_7652305_3 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 524.0
PYH2_k127_7652305_4 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 437.0
PYH2_k127_7652305_5 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 427.0
PYH2_k127_7652305_6 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 407.0
PYH2_k127_7652305_7 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 400.0
PYH2_k127_7652305_8 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 400.0
PYH2_k127_7652305_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 336.0
PYH2_k127_7695471_0 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000677 189.0
PYH2_k127_7695471_1 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000454 181.0
PYH2_k127_7723188_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K12452,K13328 - 1.17.1.1,4.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 512.0
PYH2_k127_7723188_1 PFAM NAD dependent epimerase dehydratase family K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 415.0
PYH2_k127_7723188_2 GDP-mannose 4,6 dehydratase K01784,K20534 - 5.1.3.2 0.000000000000000000000000000000000000000003296 166.0
PYH2_k127_7733609_0 Histidine kinase A domain protein - - - 2.069e-280 883.0
PYH2_k127_7733609_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 459.0
PYH2_k127_7733609_2 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 365.0
PYH2_k127_7733609_3 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 319.0
PYH2_k127_7741431_0 cation efflux system protein (Heavy metal efflux pump) - - - 2.27e-322 1017.0
PYH2_k127_7741431_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 583.0
PYH2_k127_7741431_10 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000003285 130.0
PYH2_k127_7741431_11 - - - - 0.00000000000000000000000000001693 122.0
PYH2_k127_7741431_12 Domain of unknown function (DUF4115) - - - 0.0000000000000000000000001094 119.0
PYH2_k127_7741431_13 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000001592 83.0
PYH2_k127_7741431_14 - - - - 0.000009668 53.0
PYH2_k127_7741431_15 Succinate dehydrogenase hydrophobic membrane anchor K00242 - - 0.00007547 49.0
PYH2_k127_7741431_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 563.0
PYH2_k127_7741431_3 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
PYH2_k127_7741431_4 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
PYH2_k127_7741431_5 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000006397 229.0
PYH2_k127_7741431_6 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.000000000000000000000000000000000000000000000000000000006641 209.0
PYH2_k127_7741431_7 phosphonoacetaldehyde hydrolase activity K05306,K07025,K19270 - 3.1.3.23,3.11.1.1 0.0000000000000000000000000000000000000000000000000000005089 200.0
PYH2_k127_7741431_8 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000003 198.0
PYH2_k127_7741431_9 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000009127 142.0
PYH2_k127_7768957_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 397.0
PYH2_k127_7773508_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 494.0
PYH2_k127_7773508_1 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 379.0
PYH2_k127_7773508_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 337.0
PYH2_k127_7773508_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 321.0
PYH2_k127_7773508_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 261.0
PYH2_k127_7773508_5 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000008043 160.0
PYH2_k127_7773508_6 - - - - 0.0002456 48.0
PYH2_k127_7826286_0 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 569.0
PYH2_k127_7826286_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 308.0
PYH2_k127_7826286_2 Two component transcriptional regulator, winged helix family K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
PYH2_k127_7826286_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000007568 187.0
PYH2_k127_7826286_4 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000003179 132.0
PYH2_k127_7826286_5 domain, Protein - - - 0.0000000000000000000005979 107.0
PYH2_k127_7834430_0 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 2.893e-248 788.0
PYH2_k127_7834430_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000008932 146.0
PYH2_k127_783561_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000007911 223.0
PYH2_k127_783561_1 - - - - 0.0000000000000002747 84.0
PYH2_k127_78615_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 428.0
PYH2_k127_78615_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 414.0
PYH2_k127_78615_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 314.0
PYH2_k127_78615_3 ABC transporter K01996,K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000004495 234.0
PYH2_k127_78615_4 - - - - 0.0000000000000000000000000000000364 129.0
PYH2_k127_78615_5 iron-sulfur cluster assembly - - - 0.00000000000000000000000000000522 121.0
PYH2_k127_78615_6 - - - - 0.0001415 48.0
PYH2_k127_78615_7 COG0517 FOG CBS domain - - - 0.0004414 48.0
PYH2_k127_7869122_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.551e-200 633.0
PYH2_k127_7869122_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 499.0
PYH2_k127_7869122_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000115 165.0
PYH2_k127_7869122_11 Metal-sensitive transcriptional repressor K21600 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000003789 74.0
PYH2_k127_7869122_12 Putative regulatory protein - - - 0.0000001262 57.0
PYH2_k127_7869122_13 - - - - 0.0002028 49.0
PYH2_k127_7869122_2 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 461.0
PYH2_k127_7869122_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 395.0
PYH2_k127_7869122_4 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000001782 244.0
PYH2_k127_7869122_5 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001175 238.0
PYH2_k127_7869122_6 4-hydroxy-2-oxoglutarate aldolase activity K18123 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.3.16 0.000000000000000000000000000000000000000000000000000000007123 206.0
PYH2_k127_7869122_7 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000009636 169.0
PYH2_k127_7869122_8 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000347 177.0
PYH2_k127_7869122_9 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000005846 165.0
PYH2_k127_7872234_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 1.286e-223 718.0
PYH2_k127_7872234_1 AAA-like domain - - - 3.015e-220 711.0
PYH2_k127_7872234_10 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006028 285.0
PYH2_k127_7872234_11 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
PYH2_k127_7872234_12 nodulation - - - 0.0000000000000000000000000000000000000000000000007698 185.0
PYH2_k127_7872234_13 PFAM Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000009356 187.0
PYH2_k127_7872234_14 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000000000000000008963 170.0
PYH2_k127_7872234_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000001705 159.0
PYH2_k127_7872234_16 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000001483 153.0
PYH2_k127_7872234_17 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000008063 127.0
PYH2_k127_7872234_18 PFAM extracellular solute-binding protein family 1 K02027,K10227 - - 0.00000000000000000000004446 113.0
PYH2_k127_7872234_19 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000001546 103.0
PYH2_k127_7872234_2 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 377.0
PYH2_k127_7872234_20 - - - - 0.000000000000000004003 93.0
PYH2_k127_7872234_21 Phospholipase_D-nuclease N-terminal - - - 0.00000000000004698 74.0
PYH2_k127_7872234_22 ABC-2 family transporter protein K01992 - - 0.0000000002361 70.0
PYH2_k127_7872234_3 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 364.0
PYH2_k127_7872234_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
PYH2_k127_7872234_5 PFAM Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 340.0
PYH2_k127_7872234_6 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 345.0
PYH2_k127_7872234_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 327.0
PYH2_k127_7872234_8 nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 313.0
PYH2_k127_7872234_9 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
PYH2_k127_7890148_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.066e-300 950.0
PYH2_k127_7890148_1 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 526.0
PYH2_k127_7890148_10 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000001898 202.0
PYH2_k127_7890148_11 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000001869 207.0
PYH2_k127_7890148_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000001286 155.0
PYH2_k127_7890148_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997,K18014 - 2.7.8.7,4.3.1.14 0.000000000000000000000000000001557 124.0
PYH2_k127_7890148_14 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000000001504 117.0
PYH2_k127_7890148_15 PFAM zinc finger, SWIM domain protein - - - 0.0000000000001835 74.0
PYH2_k127_7890148_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 449.0
PYH2_k127_7890148_3 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 423.0
PYH2_k127_7890148_4 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 382.0
PYH2_k127_7890148_5 L-asparaginase II K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 327.0
PYH2_k127_7890148_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 331.0
PYH2_k127_7890148_7 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 305.0
PYH2_k127_7890148_8 regulation of circadian rhythm K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
PYH2_k127_7890148_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 257.0
PYH2_k127_7896703_0 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000001875 206.0
PYH2_k127_7911049_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 310.0
PYH2_k127_7911049_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 295.0
PYH2_k127_7911049_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 286.0
PYH2_k127_7911049_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000007739 246.0
PYH2_k127_7911049_4 - - - - 0.000000000000000000000000000008574 128.0
PYH2_k127_7911049_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000001446 83.0
PYH2_k127_7915070_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.468e-251 802.0
PYH2_k127_7915070_1 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 340.0
PYH2_k127_7915070_2 pathogenesis K21471,K21687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000197 279.0
PYH2_k127_7915070_3 -O-antigen K01179,K05991,K13009 - 3.2.1.123,3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000001149 265.0
PYH2_k127_7915070_4 sirohydrochlorin cobaltochelatase activity - - - 0.0000000000000000000000000000001035 128.0
PYH2_k127_7915070_5 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000346 110.0
PYH2_k127_7915070_6 Putative ABC-transporter type IV - - - 0.000000000004418 68.0
PYH2_k127_7915070_7 sirohydrochlorin cobaltochelatase activity - - - 0.00000002526 63.0
PYH2_k127_795867_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 411.0
PYH2_k127_795867_1 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004028 263.0
PYH2_k127_795867_2 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000001996 193.0
PYH2_k127_795867_3 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000002883 158.0
PYH2_k127_795867_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000001389 106.0
PYH2_k127_795867_5 Domain of unknown function (DU1801) - - - 0.00000000000000000006585 96.0
PYH2_k127_795867_6 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000003607 85.0
PYH2_k127_795867_7 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000009192 74.0
PYH2_k127_7990742_0 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000008244 191.0
PYH2_k127_7990742_1 Glycosyl hydrolase family 36 C-terminal domain - - - 0.000000000003413 77.0
PYH2_k127_7992347_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.24e-198 628.0
PYH2_k127_7992347_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 556.0
PYH2_k127_7992347_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 417.0
PYH2_k127_7992347_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 312.0
PYH2_k127_7992347_4 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000001634 235.0
PYH2_k127_7992347_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000008488 103.0
PYH2_k127_7992347_6 - - - - 0.00002069 51.0
PYH2_k127_7992347_7 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0004362 43.0
PYH2_k127_799317_0 N-terminal 7TM region of histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 424.0
PYH2_k127_799317_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 343.0
PYH2_k127_799317_10 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000002317 72.0
PYH2_k127_799317_11 self proteolysis K07004 - - 0.0008198 50.0
PYH2_k127_799317_2 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 299.0
PYH2_k127_799317_3 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 277.0
PYH2_k127_799317_4 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006356 256.0
PYH2_k127_799317_5 PFAM membrane-flanked domain - - - 0.0000000000000000000000000000000000000006041 157.0
PYH2_k127_799317_6 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000004986 123.0
PYH2_k127_799317_7 acetyltransferase K06889,K19273 - - 0.00000000000000000000000000001273 125.0
PYH2_k127_799317_8 Domain of unknown function (DUF4342) - - - 0.0000000000000000000001019 100.0
PYH2_k127_799317_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000005891 92.0
PYH2_k127_8011714_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 5.93e-281 877.0
PYH2_k127_8011714_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000001872 153.0
PYH2_k127_8011714_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000195 153.0
PYH2_k127_8011714_3 Universal stress protein - - - 0.0000000000000000000000000000000001912 136.0
PYH2_k127_8011714_4 VIT family - - - 0.0000000000000000000000000000001775 134.0
PYH2_k127_8011714_5 GPI ethanolamine phosphate transferase 2 K05310 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016254,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0019637,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0051267,GO:0051377,GO:0071704,GO:0090407,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 - 0.00000000000000000002551 106.0
PYH2_k127_8045946_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 413.0
PYH2_k127_8048772_0 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 451.0
PYH2_k127_8048772_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 430.0
PYH2_k127_8048772_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 360.0
PYH2_k127_8048772_3 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000005867 109.0
PYH2_k127_8049739_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.321e-199 629.0
PYH2_k127_8049739_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 594.0
PYH2_k127_8049739_10 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009473 280.0
PYH2_k127_8049739_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000007394 255.0
PYH2_k127_8049739_12 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000000000000005724 207.0
PYH2_k127_8049739_13 alpha, beta K06889 - - 0.0000000000000000000000000000000000000005692 157.0
PYH2_k127_8049739_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000001248 135.0
PYH2_k127_8049739_15 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000228 126.0
PYH2_k127_8049739_16 Creatinine amidohydrolase - - - 0.00000000000000000000000001063 124.0
PYH2_k127_8049739_17 - - - - 0.00000000000000000004248 103.0
PYH2_k127_8049739_18 exo-alpha-(2->6)-sialidase activity - - - 0.0000000001452 74.0
PYH2_k127_8049739_19 - - - - 0.0000002076 56.0
PYH2_k127_8049739_2 PFAM peptidase S15 K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 484.0
PYH2_k127_8049739_21 Acetyltransferase - - - 0.000134 44.0
PYH2_k127_8049739_3 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 460.0
PYH2_k127_8049739_4 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 402.0
PYH2_k127_8049739_5 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 392.0
PYH2_k127_8049739_6 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 395.0
PYH2_k127_8049739_7 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 357.0
PYH2_k127_8049739_8 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 327.0
PYH2_k127_8049739_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004841 284.0
PYH2_k127_8050718_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 453.0
PYH2_k127_8050718_1 response to abiotic stimulus - - - 0.000000000000000000000000000000000000000000000000001161 191.0
PYH2_k127_8050718_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000002045 64.0
PYH2_k127_8050718_3 Histidine kinase - - - 0.0004212 52.0
PYH2_k127_8057507_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 6.837e-294 911.0
PYH2_k127_8057507_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 504.0
PYH2_k127_8057507_10 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000003839 64.0
PYH2_k127_8057507_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 357.0
PYH2_k127_8057507_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 317.0
PYH2_k127_8057507_4 Phage shock protein A K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
PYH2_k127_8057507_5 PFAM Helicase conserved C-terminal domain K06877 - - 0.00000000000000000000000000000000000000000002614 165.0
PYH2_k127_8057507_7 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000001372 111.0
PYH2_k127_8057507_8 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000008007 102.0
PYH2_k127_8057507_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000001802 94.0
PYH2_k127_8062483_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 580.0
PYH2_k127_8062483_1 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 343.0
PYH2_k127_8062483_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000004991 229.0
PYH2_k127_8081127_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 398.0
PYH2_k127_8081127_1 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 357.0
PYH2_k127_8081127_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 322.0
PYH2_k127_8081127_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003745 235.0
PYH2_k127_8081127_4 CpXC protein - - - 0.000000000000000000000000000000000000000000000000000000000000009874 233.0
PYH2_k127_8129259_0 ADP binding - - - 2.261e-210 684.0
PYH2_k127_8129259_1 ADP binding - - - 2.303e-199 651.0
PYH2_k127_8129259_2 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 657.0
PYH2_k127_8129259_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 558.0
PYH2_k127_8129259_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 363.0
PYH2_k127_8129259_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000001186 214.0
PYH2_k127_8129259_6 Protein of unknown function (DUF3887) K06889 - - 0.00002086 53.0
PYH2_k127_8129259_7 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0001125 48.0
PYH2_k127_8138827_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000003185 235.0
PYH2_k127_8138827_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002205 219.0
PYH2_k127_8138827_2 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000001888 172.0
PYH2_k127_8138827_4 Transglycosylase SLT domain - - - 0.00000000000001727 83.0
PYH2_k127_8138869_0 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 469.0
PYH2_k127_8138869_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 454.0
PYH2_k127_8138869_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009795 268.0
PYH2_k127_8138869_3 membrane - - - 0.00000000000000000000000983 111.0
PYH2_k127_8138869_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000002738 68.0
PYH2_k127_8138869_5 metallopeptidase activity - - - 0.00006425 55.0
PYH2_k127_8139225_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 381.0
PYH2_k127_8139225_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000002209 250.0
PYH2_k127_8202435_0 ATPase activity K02045 - 3.6.3.25 9.545e-221 702.0
PYH2_k127_8202435_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 616.0
PYH2_k127_8202435_2 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 475.0
PYH2_k127_8202435_3 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 344.0
PYH2_k127_8202435_4 ATPase-coupled sulfate transmembrane transporter activity K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 328.0
PYH2_k127_8202435_5 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 307.0
PYH2_k127_8202435_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000009799 199.0
PYH2_k127_8202435_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000001366 111.0
PYH2_k127_8202435_8 SMART zinc finger, RanBP2-type - - - 0.00006493 48.0
PYH2_k127_8211035_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002938 262.0
PYH2_k127_8250347_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.35e-250 788.0
PYH2_k127_8250347_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 3.083e-218 691.0
PYH2_k127_8250347_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 317.0
PYH2_k127_8250347_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 305.0
PYH2_k127_8250347_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000001865 200.0
PYH2_k127_8250347_5 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000004391 140.0
PYH2_k127_8250347_6 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000167 128.0
PYH2_k127_8250347_7 HAD-superfamily subfamily IB hydrolase, TIGR01490 K00655,K15781 - 2.3.1.51,3.1.3.3 0.000000000000000001417 96.0
PYH2_k127_8250347_8 diacylglycerol kinase, catalytic region - - - 0.00000003371 58.0
PYH2_k127_8281816_0 SPTR Transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 397.0
PYH2_k127_8281816_1 PFAM tRNA rRNA methyltransferase (SpoU) K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
PYH2_k127_8281816_2 PFAM Integrase core domain K07497 - - 0.00008235 46.0
PYH2_k127_8311550_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000001238 117.0
PYH2_k127_8311550_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000007008 110.0
PYH2_k127_8311550_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000338 106.0
PYH2_k127_8325289_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 423.0
PYH2_k127_8325289_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000127 167.0
PYH2_k127_8325289_2 ATP:ADP antiporter activity K15762 - - 0.0000000000000000000000000000000001209 149.0
PYH2_k127_8325289_3 membrane transporter protein K07090 - - 0.000000000003169 68.0
PYH2_k127_8325289_4 Type IV pilus biogenesis stability protein PilW - - - 0.00000000001123 76.0
PYH2_k127_8325289_5 Biotin-lipoyl like K01993 - - 0.00000000005586 67.0
PYH2_k127_8339664_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 2.406e-267 833.0
PYH2_k127_8339664_1 Beta-lactamase - - - 8.648e-208 658.0
PYH2_k127_8339664_10 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000005506 192.0
PYH2_k127_8339664_11 - - - - 0.00000000000000000000000000000000000000005434 162.0
PYH2_k127_8339664_12 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000007694 155.0
PYH2_k127_8339664_13 Universal stress protein family - - - 0.0000000000000000000002983 102.0
PYH2_k127_8339664_15 Tetratricopeptide repeat - - - 0.00000002067 66.0
PYH2_k127_8339664_2 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 578.0
PYH2_k127_8339664_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 530.0
PYH2_k127_8339664_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 511.0
PYH2_k127_8339664_5 (ABC) transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 510.0
PYH2_k127_8339664_6 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 376.0
PYH2_k127_8339664_7 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
PYH2_k127_8339664_8 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005312 300.0
PYH2_k127_8339664_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
PYH2_k127_8358585_0 PFAM Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 340.0
PYH2_k127_8358585_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01083,K06131,K06915 - 3.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 360.0
PYH2_k127_8358585_2 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000002218 150.0
PYH2_k127_8401198_0 Rad50 zinc hook motif K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001156 252.0
PYH2_k127_8401198_1 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000001466 134.0
PYH2_k127_8401198_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000393 48.0
PYH2_k127_8413799_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 352.0
PYH2_k127_8418647_0 PFAM aminotransferase class V K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 475.0
PYH2_k127_8418647_1 Belongs to the MenA family. Type 1 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 291.0
PYH2_k127_8418647_2 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
PYH2_k127_8418647_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000004081 160.0
PYH2_k127_8418647_4 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity - - - 0.000000000000000000000000000000000002432 150.0
PYH2_k127_8418647_5 Ig-like domain from next to BRCA1 gene - - - 0.00000000003437 74.0
PYH2_k127_8418647_6 PFAM pentapeptide repeat protein - - - 0.0000000125 61.0
PYH2_k127_8426964_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1790.0
PYH2_k127_8426964_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 1.257e-235 739.0
PYH2_k127_8426964_10 oxidation-reduction process - - - 0.000000000000000000000000000000000000005975 151.0
PYH2_k127_8426964_11 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000001657 138.0
PYH2_k127_8426964_12 ACT domain - - - 0.00000000003168 72.0
PYH2_k127_8426964_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 503.0
PYH2_k127_8426964_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 426.0
PYH2_k127_8426964_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 391.0
PYH2_k127_8426964_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 385.0
PYH2_k127_8426964_6 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 355.0
PYH2_k127_8426964_7 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 352.0
PYH2_k127_8426964_8 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 352.0
PYH2_k127_8426964_9 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
PYH2_k127_844609_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 343.0
PYH2_k127_844609_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001613 279.0
PYH2_k127_844609_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005966 220.0
PYH2_k127_844609_3 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.000000000000000000000000007462 120.0
PYH2_k127_844609_5 DNA methylase K07316 - 2.1.1.72 0.000000001856 61.0
PYH2_k127_844609_6 - - - - 0.000000004146 64.0
PYH2_k127_844609_7 Protein of unknown function (DUF1706) - - - 0.000002114 51.0
PYH2_k127_844609_8 Restriction endonuclease - - - 0.00004521 54.0
PYH2_k127_8453778_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005544 252.0
PYH2_k127_8453778_1 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0000000002887 70.0
PYH2_k127_8453778_2 ABC-2 type transporter K01992 - - 0.000001145 51.0
PYH2_k127_8456061_0 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000005907 205.0
PYH2_k127_8456061_1 B3/4 domain - - - 0.00000000000000000000000000000000001873 147.0
PYH2_k127_8456061_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000007155 126.0
PYH2_k127_8456831_0 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 426.0
PYH2_k127_8456831_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 386.0
PYH2_k127_8456831_10 - - - - 0.0000000000000000000002253 100.0
PYH2_k127_8456831_11 transposase activity - - - 0.000000000000003382 76.0
PYH2_k127_8456831_12 Glycosyltransferase Family 4 - - - 0.00000000000005406 82.0
PYH2_k127_8456831_13 membrane - - - 0.00000002971 64.0
PYH2_k127_8456831_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 385.0
PYH2_k127_8456831_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 293.0
PYH2_k127_8456831_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007976 293.0
PYH2_k127_8456831_5 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 280.0
PYH2_k127_8456831_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000002231 230.0
PYH2_k127_8456831_7 sptr a7nhu5 - - - 0.0000000000000000000000000000000000000000000003448 169.0
PYH2_k127_8456831_8 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000003404 167.0
PYH2_k127_8456831_9 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000005045 144.0
PYH2_k127_8461061_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 391.0
PYH2_k127_8461061_1 YbbR-like protein - - - 0.000000000000008523 87.0
PYH2_k127_8463224_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1380.0
PYH2_k127_8463224_1 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000001457 145.0
PYH2_k127_8463224_3 PFAM TadE family protein K12287 - - 0.00000000000000002734 92.0
PYH2_k127_8463224_4 PFAM TadE family protein - - - 0.00000000000002934 81.0
PYH2_k127_846773_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 504.0
PYH2_k127_846773_1 pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000001632 70.0
PYH2_k127_8473474_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 299.0
PYH2_k127_8473474_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000002381 263.0
PYH2_k127_8473474_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000001584 166.0
PYH2_k127_8473474_3 response regulator K07689 - - 0.000000000000000000000001549 110.0
PYH2_k127_8478936_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 449.0
PYH2_k127_8478936_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000007189 168.0
PYH2_k127_8478936_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000004846 160.0
PYH2_k127_8478936_3 TIGRFAM YgiT-type zinc finger domain - - - 0.0000000000107 66.0
PYH2_k127_8478936_4 ThiS family K03636 - - 0.0009954 50.0
PYH2_k127_8494466_0 cheY-homologous receiver domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 404.0
PYH2_k127_8494466_1 SMART HTH transcriptional regulator, Crp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 353.0
PYH2_k127_8494466_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000008689 80.0
PYH2_k127_8498330_0 Molydopterin dinucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 581.0
PYH2_k127_8498330_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 495.0
PYH2_k127_8498330_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 346.0
PYH2_k127_8498330_3 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 357.0
PYH2_k127_8498330_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000002661 183.0
PYH2_k127_8498330_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000003134 149.0
PYH2_k127_8498330_6 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000006559 112.0
PYH2_k127_8498330_7 Cytochrome c - - - 0.0000000000000000000001007 111.0
PYH2_k127_8498330_8 Integrase core domain K07497 - - 0.000000000000000000005264 97.0
PYH2_k127_8498330_9 Oxidoreductase molybdopterin binding domain - - - 0.00000596 55.0
PYH2_k127_8500004_0 ABC transporter, transmembrane region K06147 - - 1.021e-233 736.0
PYH2_k127_8500004_1 PFAM ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 501.0
PYH2_k127_8500004_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000002947 171.0
PYH2_k127_8529434_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000001895 164.0
PYH2_k127_8529434_1 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000001082 99.0
PYH2_k127_8538040_0 5'-nucleotidase, C-terminal domain - - - 0.0 1406.0
PYH2_k127_8538040_1 Extracellular nuclease K07004 - - 8.549e-210 689.0
PYH2_k127_8538040_2 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 556.0
PYH2_k127_8538040_3 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
PYH2_k127_8538040_4 HYR domain - - - 0.000000000000000000000000000000000003667 160.0
PYH2_k127_8538040_6 - - - - 0.0003448 55.0
PYH2_k127_8548576_0 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 479.0
PYH2_k127_8548576_1 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 294.0
PYH2_k127_8548576_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000005438 102.0
PYH2_k127_8548576_3 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000001897 76.0
PYH2_k127_8550611_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 5.885e-194 622.0
PYH2_k127_8550611_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 642.0
PYH2_k127_8550611_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000007036 171.0
PYH2_k127_8550611_11 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000000000000000004361 151.0
PYH2_k127_8550611_12 SMART protein phosphatase 2C domain protein - - - 0.00000000000000295 91.0
PYH2_k127_8550611_13 phosphorelay sensor kinase activity K02660,K03406,K11525 - - 0.000005326 60.0
PYH2_k127_8550611_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007043 277.0
PYH2_k127_8550611_3 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000001259 247.0
PYH2_k127_8550611_4 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003494 243.0
PYH2_k127_8550611_5 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003883 249.0
PYH2_k127_8550611_6 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000003899 211.0
PYH2_k127_8550611_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000218 202.0
PYH2_k127_8550611_8 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000003771 206.0
PYH2_k127_8550611_9 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.000000000000000000000000000000000000000000000008657 197.0
PYH2_k127_8557658_0 domain, Protein K03980,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000653 184.0
PYH2_k127_8557658_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000001791 179.0
PYH2_k127_8570512_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 4.479e-245 769.0
PYH2_k127_8570512_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 352.0
PYH2_k127_8570512_2 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002599 263.0
PYH2_k127_8570512_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000344 102.0
PYH2_k127_8570512_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000003919 87.0
PYH2_k127_8578806_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 5.834e-215 674.0
PYH2_k127_8578806_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.778e-212 678.0
PYH2_k127_8578806_10 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009456 245.0
PYH2_k127_8578806_11 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000001468 233.0
PYH2_k127_8578806_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000001221 216.0
PYH2_k127_8578806_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000003331 201.0
PYH2_k127_8578806_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000005812 153.0
PYH2_k127_8578806_15 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000000000000000002788 143.0
PYH2_k127_8578806_16 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000004569 128.0
PYH2_k127_8578806_17 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000109 113.0
PYH2_k127_8578806_18 sulfur carrier activity - - - 0.000000000000000000001884 98.0
PYH2_k127_8578806_19 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000000000000007518 97.0
PYH2_k127_8578806_2 Ferrous iron transport protein B C terminus K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 602.0
PYH2_k127_8578806_20 Asp23 family, cell envelope-related function - - - 0.000000000000000000009981 95.0
PYH2_k127_8578806_21 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000001181 96.0
PYH2_k127_8578806_22 Protein of unknown function (DUF4230) - - - 0.000000000000000001099 94.0
PYH2_k127_8578806_23 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000001344 69.0
PYH2_k127_8578806_24 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000001677 66.0
PYH2_k127_8578806_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000006282 72.0
PYH2_k127_8578806_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000001831 56.0
PYH2_k127_8578806_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 476.0
PYH2_k127_8578806_4 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 398.0
PYH2_k127_8578806_5 Ferrous iron transport protein B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 361.0
PYH2_k127_8578806_6 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
PYH2_k127_8578806_7 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 300.0
PYH2_k127_8578806_8 iron ion homeostasis K03322,K03709,K04758 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 305.0
PYH2_k127_8578806_9 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002615 289.0
PYH2_k127_8584047_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.103e-308 982.0
PYH2_k127_8584047_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.94e-246 774.0
PYH2_k127_8584047_10 Aldehyde ferredoxin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 363.0
PYH2_k127_8584047_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 333.0
PYH2_k127_8584047_12 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
PYH2_k127_8584047_13 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 337.0
PYH2_k127_8584047_14 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 335.0
PYH2_k127_8584047_15 PFAM Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 337.0
PYH2_k127_8584047_16 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 336.0
PYH2_k127_8584047_17 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 310.0
PYH2_k127_8584047_18 Electron transfer flavoprotein FAD-binding domain K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 295.0
PYH2_k127_8584047_19 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 286.0
PYH2_k127_8584047_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.341e-243 764.0
PYH2_k127_8584047_20 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003384 278.0
PYH2_k127_8584047_21 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002923 276.0
PYH2_k127_8584047_22 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006625 276.0
PYH2_k127_8584047_23 PFAM electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009107 265.0
PYH2_k127_8584047_24 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000002127 240.0
PYH2_k127_8584047_25 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001558 232.0
PYH2_k127_8584047_26 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000005035 205.0
PYH2_k127_8584047_27 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000000005387 179.0
PYH2_k127_8584047_28 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000001229 171.0
PYH2_k127_8584047_29 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000002703 145.0
PYH2_k127_8584047_3 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 9.039e-210 703.0
PYH2_k127_8584047_30 - - - - 0.0000000000000000000000000000000003517 144.0
PYH2_k127_8584047_31 TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000002036 132.0
PYH2_k127_8584047_32 - - - - 0.0000000000000000000000000006443 120.0
PYH2_k127_8584047_33 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000004499 104.0
PYH2_k127_8584047_34 Transmembrane secretion effector - - - 0.0000000000000000000005373 106.0
PYH2_k127_8584047_36 Uncharacterised protein family (UPF0158) - - - 0.000000000000004092 81.0
PYH2_k127_8584047_4 Aminotransferase class-III - - - 2.573e-201 637.0
PYH2_k127_8584047_5 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 513.0
PYH2_k127_8584047_6 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 484.0
PYH2_k127_8584047_7 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 446.0
PYH2_k127_8584047_8 transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 439.0
PYH2_k127_8584047_9 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 380.0
PYH2_k127_8586205_0 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 385.0
PYH2_k127_8586205_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 290.0
PYH2_k127_8586205_2 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 276.0
PYH2_k127_8588164_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1032.0
PYH2_k127_8588164_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 521.0
PYH2_k127_8588164_2 PFAM AAA-4 family protein K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 501.0
PYH2_k127_8588164_3 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 437.0
PYH2_k127_8588164_4 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 334.0
PYH2_k127_8588164_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 311.0
PYH2_k127_8588164_6 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000001944 223.0
PYH2_k127_8588164_7 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000364 177.0
PYH2_k127_8588164_8 HEPN domain - - - 0.00000000575 67.0
PYH2_k127_8588164_9 Nucleotidyltransferase domain - - - 0.000005777 57.0
PYH2_k127_862124_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 444.0
PYH2_k127_862124_1 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
PYH2_k127_862124_2 Transposase IS200 like - - - 0.00000000000000000000000000000000000000001062 160.0
PYH2_k127_862124_3 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000641 151.0
PYH2_k127_862124_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000003123 76.0
PYH2_k127_8628997_0 PFAM glycosyl transferase, family 51 - - - 8.486e-267 853.0
PYH2_k127_8628997_1 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 347.0
PYH2_k127_8628997_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 303.0
PYH2_k127_8628997_3 Sigma-70, region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005062 272.0
PYH2_k127_8628997_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003736 256.0
PYH2_k127_8628997_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000001717 196.0
PYH2_k127_8628997_6 - - - - 0.00000000000000000000000363 106.0
PYH2_k127_8628997_7 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0000000000000000000001152 111.0
PYH2_k127_8628997_8 Pfam:Pyridox_oxidase K09979 - - 0.000000000000003199 82.0
PYH2_k127_8629151_0 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000001253 200.0
PYH2_k127_8629151_1 Galactose oxidase, central domain - - - 0.000000000000000000000001234 122.0
PYH2_k127_8629151_2 membrane organization K07126,K07277 - - 0.0000000000000000008996 103.0
PYH2_k127_8629151_3 - - - - 0.000000000000007587 83.0
PYH2_k127_8629151_4 rRNA binding - - - 0.00000002416 63.0
PYH2_k127_8632714_0 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 351.0
PYH2_k127_8632714_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 355.0
PYH2_k127_8632714_2 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003374 293.0
PYH2_k127_8632714_3 - - - - 0.00000000000000000000000000000000002375 144.0
PYH2_k127_8632714_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000587 145.0
PYH2_k127_8632714_5 - - - - 0.00000000000000001245 95.0
PYH2_k127_8648527_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 287.0
PYH2_k127_8648527_1 PIN domain - - - 0.00000144 57.0
PYH2_k127_8654968_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 419.0
PYH2_k127_8654968_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 381.0
PYH2_k127_8654968_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 323.0
PYH2_k127_8654968_3 cellular response to dsDNA K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004402 275.0
PYH2_k127_8654968_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.000000000000000000000000000000000000000000000000000001518 198.0
PYH2_k127_8654968_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000004189 192.0
PYH2_k127_8654968_6 proteolysis - - - 0.00000000000000000000000000007953 121.0
PYH2_k127_8654968_7 ThiS family K03636,K21147 - 2.7.7.80,2.8.1.11 0.0002263 45.0
PYH2_k127_8659773_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 6.041e-225 707.0
PYH2_k127_8659773_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 399.0
PYH2_k127_8659773_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 361.0
PYH2_k127_8659773_3 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 325.0
PYH2_k127_8659773_4 Belongs to the TtcA family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 302.0
PYH2_k127_8659773_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000002431 190.0
PYH2_k127_8659773_6 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000003543 204.0
PYH2_k127_8659773_7 Transcriptional regulator - - - 0.0000000000000000000000003154 117.0
PYH2_k127_8659773_8 thiamine diphosphate biosynthetic process K03154 - - 0.0000008603 53.0
PYH2_k127_8702133_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 452.0
PYH2_k127_8702133_1 Pfam:DUF2276 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
PYH2_k127_8702133_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000001486 197.0
PYH2_k127_8702133_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0000000000000000000000000001238 117.0
PYH2_k127_8709126_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 1.243e-236 751.0
PYH2_k127_8709126_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 587.0
PYH2_k127_8709126_10 DGC domain - - - 0.00000000000000000000006992 103.0
PYH2_k127_8709126_12 Thioredoxin domain - - - 0.0000000002363 68.0
PYH2_k127_8709126_2 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 510.0
PYH2_k127_8709126_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 355.0
PYH2_k127_8709126_4 Putative Fe-S cluster - - - 0.00000000000000000000000000000000000002515 149.0
PYH2_k127_8709126_5 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000000002153 135.0
PYH2_k127_8709126_6 OsmC-like protein - - - 0.0000000000000000000000000000008305 128.0
PYH2_k127_8709126_7 DGC domain - - - 0.0000000000000000000000000007078 123.0
PYH2_k127_8709126_8 Thioredoxin domain - - - 0.000000000000000000000002709 104.0
PYH2_k127_8709126_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000001817 108.0
PYH2_k127_8711392_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 447.0
PYH2_k127_8711392_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
PYH2_k127_8711392_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000001501 227.0
PYH2_k127_8711392_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000001921 214.0
PYH2_k127_8711392_4 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000005316 187.0
PYH2_k127_8711392_5 DOMON domain-containing protein - - - 0.00000000000000000000000000000000000002061 155.0
PYH2_k127_8711392_6 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000005176 132.0
PYH2_k127_8711392_7 - - - - 0.00000000000000000000000001006 125.0
PYH2_k127_878439_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 520.0
PYH2_k127_878439_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 510.0
PYH2_k127_878439_10 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000002513 194.0
PYH2_k127_878439_11 MGS-like domain K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000000001386 179.0
PYH2_k127_878439_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000005927 159.0
PYH2_k127_878439_13 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000004779 131.0
PYH2_k127_878439_14 TIGRFAM integral membrane protein TIGR01906 - - - 0.000000000000000000000000000002513 129.0
PYH2_k127_878439_15 ammonium transporteR K03320 - - 0.000000000000000000000000000004947 136.0
PYH2_k127_878439_16 Major facilitator superfamily - - - 0.00000000000000000000000000001981 132.0
PYH2_k127_878439_17 Major facilitator superfamily K08161 - - 0.0000000000000000000000000001654 129.0
PYH2_k127_878439_18 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000325 115.0
PYH2_k127_878439_19 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000004883 115.0
PYH2_k127_878439_2 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 482.0
PYH2_k127_878439_20 - - - - 0.0000000000000000000000009309 108.0
PYH2_k127_878439_21 - - - - 0.0000000000000205 86.0
PYH2_k127_878439_3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 473.0
PYH2_k127_878439_4 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 433.0
PYH2_k127_878439_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 404.0
PYH2_k127_878439_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 346.0
PYH2_k127_878439_7 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 309.0
PYH2_k127_878439_8 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000008355 251.0
PYH2_k127_878439_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000001028 213.0
PYH2_k127_8793761_0 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 562.0
PYH2_k127_8793761_1 membrane protein, terc K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 526.0
PYH2_k127_8793761_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 378.0
PYH2_k127_8793761_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009449 245.0
PYH2_k127_8793761_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001129 216.0
PYH2_k127_8793761_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.0000000000006673 76.0
PYH2_k127_8794952_0 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.0 1353.0
PYH2_k127_8794952_1 COG1982 Arginine lysine ornithine decarboxylases K01582,K01584 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019001,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.1.1.18,4.1.1.19 1.909e-314 981.0
PYH2_k127_8794952_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 355.0
PYH2_k127_8794952_3 Amino acid permease K03756 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005143 242.0
PYH2_k127_879731_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000006274 179.0
PYH2_k127_879731_1 Protein kinase domain - - - 0.00000000000000000000000000000001666 138.0
PYH2_k127_879731_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000002463 94.0
PYH2_k127_879731_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000148 77.0
PYH2_k127_879731_4 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.00000000229 65.0
PYH2_k127_879731_5 STAS domain - - - 0.000001651 55.0
PYH2_k127_879731_6 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00009713 50.0
PYH2_k127_8811743_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
PYH2_k127_8811743_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000022 232.0
PYH2_k127_8811743_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000002475 198.0
PYH2_k127_8829767_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 332.0
PYH2_k127_8829767_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000002246 173.0
PYH2_k127_8829767_2 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.000000000000000000000000000000000000000006767 159.0
PYH2_k127_8829767_3 PFAM helix-turn-helix domain protein - - - 0.0000000000000005566 83.0
PYH2_k127_8829767_4 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0000000001368 67.0
PYH2_k127_8830487_0 PFAM Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 358.0
PYH2_k127_8830487_1 IMG reference gene - - - 0.0000000000000000000004294 99.0
PYH2_k127_8861720_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 381.0
PYH2_k127_8861720_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 361.0
PYH2_k127_8861720_2 sh3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001495 237.0
PYH2_k127_8861720_3 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000007399 169.0
PYH2_k127_8861720_4 integral membrane protein - - - 0.00000000000000000000000000002471 124.0
PYH2_k127_8861720_5 - - - - 0.00000000000005213 76.0
PYH2_k127_8880776_0 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 509.0
PYH2_k127_8880776_1 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 400.0
PYH2_k127_8880776_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 298.0
PYH2_k127_8880776_3 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009475 249.0
PYH2_k127_8942097_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003828 286.0
PYH2_k127_8942097_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000007031 235.0
PYH2_k127_8942097_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000108 206.0
PYH2_k127_8942097_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000363 90.0
PYH2_k127_8942097_4 response regulator K07667 - - 0.00000000000000003301 86.0
PYH2_k127_8942097_5 AAA ATPase domain - - - 0.0000000000000005375 92.0
PYH2_k127_8969989_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 335.0
PYH2_k127_8969989_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000003249 206.0
PYH2_k127_8969989_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000007582 214.0
PYH2_k127_8969989_3 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000001627 186.0
PYH2_k127_8969989_4 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000003933 92.0
PYH2_k127_8998827_0 Histidine kinase K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001054 216.0
PYH2_k127_8998827_1 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000002609 100.0
PYH2_k127_9004007_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1467.0
PYH2_k127_9004007_1 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0 1007.0
PYH2_k127_9004007_10 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001829 243.0
PYH2_k127_9004007_11 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000002768 238.0
PYH2_k127_9004007_12 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000002291 209.0
PYH2_k127_9004007_13 helix_turn_helix, Lux Regulon K07684,K07693 - - 0.000000000000000000000000000000000000000000000000001186 190.0
PYH2_k127_9004007_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000001837 193.0
PYH2_k127_9004007_15 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000002491 131.0
PYH2_k127_9004007_2 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 7.5e-203 636.0
PYH2_k127_9004007_3 xylulokinase activity K00848,K00851,K00854 - 2.7.1.12,2.7.1.17,2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 606.0
PYH2_k127_9004007_4 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 491.0
PYH2_k127_9004007_5 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 422.0
PYH2_k127_9004007_6 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 372.0
PYH2_k127_9004007_7 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 347.0
PYH2_k127_9004007_8 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 324.0
PYH2_k127_9004007_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 313.0
PYH2_k127_9010184_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 501.0
PYH2_k127_9010184_1 PFAM peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 381.0
PYH2_k127_9010184_2 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000004459 203.0
PYH2_k127_9010184_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000003892 100.0
PYH2_k127_9010184_4 PFAM GCN5-related N-acetyltransferase - - - 0.00004623 53.0
PYH2_k127_9010184_5 Bacterial pre-peptidase C-terminal domain - - - 0.0002875 51.0
PYH2_k127_9018148_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000008783 218.0
PYH2_k127_9018148_1 Membrane - - - 0.000000000005334 71.0
PYH2_k127_9024302_0 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 531.0
PYH2_k127_9024302_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 462.0
PYH2_k127_9024302_2 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
PYH2_k127_9024302_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000001366 186.0
PYH2_k127_9024302_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000002719 68.0
PYH2_k127_9035045_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 448.0
PYH2_k127_9035045_1 Peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 415.0
PYH2_k127_9035045_2 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005275 280.0
PYH2_k127_9035045_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000001898 210.0
PYH2_k127_9035045_4 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000004885 78.0
PYH2_k127_9035045_5 Cysteine-rich domain K11473 - - 0.00000003252 56.0
PYH2_k127_903819_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 401.0
PYH2_k127_903819_1 Ntpase (Nacht family) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000005203 190.0
PYH2_k127_903819_2 Hep Hag repeat protein - - - 0.0000000003039 71.0
PYH2_k127_9057178_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.347e-258 805.0
PYH2_k127_9057178_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 512.0
PYH2_k127_9057178_10 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000000001344 154.0
PYH2_k127_9057178_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000001767 143.0
PYH2_k127_9057178_12 Cytochrome c K17222 - - 0.000000000000000000000000000002367 131.0
PYH2_k127_9057178_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000001331 85.0
PYH2_k127_9057178_14 oligosaccharyl transferase activity - - - 0.000000001061 72.0
PYH2_k127_9057178_15 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000309 67.0
PYH2_k127_9057178_16 PFAM glycosyl transferase family 39 - - - 0.00002937 50.0
PYH2_k127_9057178_2 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 417.0
PYH2_k127_9057178_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 317.0
PYH2_k127_9057178_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000001195 253.0
PYH2_k127_9057178_5 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000191 215.0
PYH2_k127_9057178_6 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000000000000002031 223.0
PYH2_k127_9057178_7 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000002041 207.0
PYH2_k127_9057178_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000002578 216.0
PYH2_k127_9057178_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000004649 173.0
PYH2_k127_9058917_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 526.0
PYH2_k127_9058917_1 lipid-A-disaccharide synthase activity - - - 0.000000000000000000004683 93.0
PYH2_k127_9096908_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000002752 133.0
PYH2_k127_9096908_1 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00001327 53.0
PYH2_k127_9100572_0 Zn-dependent proteases and their inactivated homologs K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 398.0
PYH2_k127_9100572_1 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 293.0
PYH2_k127_9100572_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002597 290.0
PYH2_k127_9100572_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
PYH2_k127_9100572_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000001578 133.0
PYH2_k127_9100572_5 protein serine/threonine phosphatase activity - - - 0.0007881 51.0
PYH2_k127_9124465_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 461.0
PYH2_k127_9124465_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000005547 123.0
PYH2_k127_9124465_2 TIGRFAM carbohydrate kinase, thermoresistant glucokinase family K00851 - 2.7.1.12 0.0000000002753 61.0
PYH2_k127_9143428_0 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 404.0
PYH2_k127_9143428_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 315.0
PYH2_k127_9158075_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 597.0
PYH2_k127_9158075_1 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003834 270.0
PYH2_k127_9158075_2 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000000002775 176.0
PYH2_k127_9183396_0 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004853 273.0
PYH2_k127_9183396_1 import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001533 280.0
PYH2_k127_9183396_10 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000002241 125.0
PYH2_k127_9183396_11 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000255 90.0
PYH2_k127_9183396_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000002079 239.0
PYH2_k127_9183396_3 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 228.0
PYH2_k127_9183396_4 Belongs to the binding-protein-dependent transport system permease family K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000002312 218.0
PYH2_k127_9183396_5 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain K05346 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000002152 174.0
PYH2_k127_9183396_6 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000004695 163.0
PYH2_k127_9183396_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001564 127.0
PYH2_k127_9183396_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000001141 121.0
PYH2_k127_9183396_9 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000007893 116.0
PYH2_k127_9187222_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 450.0
PYH2_k127_9187222_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000002156 226.0
PYH2_k127_9187222_2 Transposase zinc-binding domain - - - 0.00000000000000000000000002365 110.0
PYH2_k127_9187222_3 Methyltransferase domain - - - 0.00000000004264 67.0
PYH2_k127_9187222_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00005127 46.0
PYH2_k127_9193035_0 Serine threonine protein kinase K12132 - 2.7.11.1 5.624e-210 671.0
PYH2_k127_9193035_1 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 355.0
PYH2_k127_9193035_2 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 303.0
PYH2_k127_9193035_3 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000001595 216.0
PYH2_k127_9193035_4 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.000000000000000000000000000000000123 140.0
PYH2_k127_9193035_5 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000001963 129.0
PYH2_k127_9193035_6 - - - - 0.00000000000000000002095 95.0
PYH2_k127_9193035_7 Major Facilitator Superfamily - - - 0.0000000000000000004133 91.0
PYH2_k127_9193035_8 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.00003852 47.0
PYH2_k127_9213558_0 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000002205 239.0
PYH2_k127_9213558_1 Ferritin-like - - - 0.0000000000000000000000000000000000000000000243 166.0
PYH2_k127_9213558_2 META domain K03929 - - 0.0000000000004115 81.0
PYH2_k127_9213558_3 Type III secretion system lipoprotein chaperone (YscW) - - - 0.0000000000009635 80.0
PYH2_k127_9213558_4 META domain - - - 0.000006783 58.0
PYH2_k127_9218377_0 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002646 280.0
PYH2_k127_9218377_1 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000000000000148 143.0
PYH2_k127_9218377_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000001136 88.0
PYH2_k127_9218377_3 Lycopene cyclase protein K06443 - 5.5.1.19 0.00000000002317 67.0
PYH2_k127_9247065_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 519.0
PYH2_k127_9247065_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
PYH2_k127_9247065_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000009385 209.0
PYH2_k127_9247065_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000002035 185.0
PYH2_k127_9247065_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000007823 91.0
PYH2_k127_934543_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 478.0
PYH2_k127_934543_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 364.0
PYH2_k127_934543_2 Domain of unknown function (DUF4129) - - - 0.000000000000000000000000000000000000002136 160.0
PYH2_k127_934543_4 - - - - 0.000007813 55.0
PYH2_k127_935518_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 1.11e-275 863.0
PYH2_k127_935518_1 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 591.0
PYH2_k127_935518_10 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 304.0
PYH2_k127_935518_11 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
PYH2_k127_935518_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003727 265.0
PYH2_k127_935518_14 Enoyl-CoA hydratase/isomerase K13767,K13816 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001822 246.0
PYH2_k127_935518_15 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000006328 179.0
PYH2_k127_935518_16 MarR family - - - 0.000000000000000000000000000001675 124.0
PYH2_k127_935518_17 ABC-2 family transporter protein - - - 0.000000000000000000000000000002321 125.0
PYH2_k127_935518_18 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000004423 122.0
PYH2_k127_935518_19 Helix-turn-helix of DDE superfamily endonuclease - - - 0.000000000000000000001826 98.0
PYH2_k127_935518_2 Peptidoglycan-binding domain 1 protein K01197,K02022 - 3.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 456.0
PYH2_k127_935518_20 Electron transfer flavoprotein domain K03521 - - 0.000000000000000002152 96.0
PYH2_k127_935518_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 445.0
PYH2_k127_935518_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 427.0
PYH2_k127_935518_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 400.0
PYH2_k127_935518_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 396.0
PYH2_k127_935518_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 375.0
PYH2_k127_935518_8 Domain of unknown function (DUF4874) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 358.0
PYH2_k127_935518_9 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 332.0
PYH2_k127_944698_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 541.0
PYH2_k127_944698_1 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 439.0
PYH2_k127_944698_2 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 453.0
PYH2_k127_944698_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
PYH2_k127_944698_4 serine threonine protein kinase - - - 0.00000000000000000003103 106.0
PYH2_k127_958977_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000003177 145.0
PYH2_k127_96302_0 Sigma-70, region 4 type 2 K11618 - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
PYH2_k127_96302_1 Transposase K07492 - - 0.0000000000000000000000000000000000000000000000000000009004 197.0
PYH2_k127_96302_2 Transposase K02557,K03406,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000001427 213.0
PYH2_k127_96302_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000582 178.0
PYH2_k127_96302_4 PFAM Transposase DDE domain - - - 0.0000000000000000000000000965 109.0
PYH2_k127_96302_5 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000001361 110.0
PYH2_k127_96302_6 PFAM ATP-binding region - - - 0.0000000000000000006008 103.0
PYH2_k127_96302_7 Ig-like domain from next to BRCA1 gene - - - 0.00000000000004473 86.0
PYH2_k127_96302_8 Transposase DDE domain - - - 0.000003899 48.0
PYH2_k127_967467_0 transport system K01992 - - 2.537e-273 871.0
PYH2_k127_967467_1 Domain of unknown function (DUF4340) - - - 0.000000000003587 73.0
PYH2_k127_967467_2 ABC transporter K01990 - - 0.0000001996 53.0
PYH2_k127_9739_0 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 315.0
PYH2_k127_9739_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001081 253.0
PYH2_k127_9739_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000006042 250.0
PYH2_k127_9739_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.000000000001425 70.0
PYH2_k127_976666_0 helix_turn_helix, Lux Regulon K03556 - - 4.378e-211 687.0
PYH2_k127_976666_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 373.0
PYH2_k127_976666_10 FG-GAP repeat - - - 0.00000001192 64.0
PYH2_k127_976666_11 Belongs to the peptidase S8 family - - - 0.0000005857 58.0
PYH2_k127_976666_12 Belongs to the peptidase S8 family - - - 0.0000007221 63.0
PYH2_k127_976666_13 - - - - 0.00004395 54.0
PYH2_k127_976666_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 266.0
PYH2_k127_976666_3 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001353 255.0
PYH2_k127_976666_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000003419 111.0
PYH2_k127_976666_6 methyltransferase activity - - - 0.0000000000000001657 83.0
PYH2_k127_976666_7 Domain of unknown function (DUF4386) - - - 0.0000000000000006209 81.0
PYH2_k127_976666_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000001919 88.0
PYH2_k127_977767_0 Negative regulator of - - - 0.0000000351 66.0
PYH2_k127_978760_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1213.0
PYH2_k127_978760_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 570.0
PYH2_k127_978760_10 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000000000006785 94.0
PYH2_k127_978760_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 417.0
PYH2_k127_978760_3 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 351.0
PYH2_k127_978760_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 316.0
PYH2_k127_978760_5 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001427 297.0
PYH2_k127_978760_6 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000001634 216.0
PYH2_k127_978760_7 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000007535 199.0
PYH2_k127_978760_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000004698 143.0
PYH2_k127_978760_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000002561 114.0
PYH2_k127_984310_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 441.0
PYH2_k127_984310_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 337.0
PYH2_k127_984310_10 Putative regulatory protein - - - 0.0000000000000004033 84.0
PYH2_k127_984310_11 Domain of unknown function (DUF1992) - - - 0.0000000001453 70.0
PYH2_k127_984310_12 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.000000008014 65.0
PYH2_k127_984310_2 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 309.0
PYH2_k127_984310_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007353 247.0
PYH2_k127_984310_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009226 233.0
PYH2_k127_984310_5 response regulator, receiver K09763 - - 0.000000000000000000000000000000000000000000000000004406 191.0
PYH2_k127_984310_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000423 176.0
PYH2_k127_984310_7 Conserved hypothetical protein 95 K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000002267 178.0
PYH2_k127_984310_8 Tetratricopeptide repeat - - - 0.0000000000000000000000373 112.0
PYH2_k127_984310_9 - - - - 0.0000000000000000000006079 100.0
PYH2_k127_989802_0 including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 433.0
PYH2_k127_989802_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 420.0
PYH2_k127_989802_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
PYH2_k127_989802_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000003664 190.0
PYH2_k127_989802_4 Lipopolysaccharide biosynthesis protein - - - 0.00000000000000003178 88.0
PYH2_k127_989802_5 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000004122 63.0