Overview

ID MAG03193
Name PYH2_bin.44
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class WTBG01
Order WTBG01
Family WTBG01
Genus CALJBY01
Species
Assembly information
Completeness (%) 88.0
Contamination (%) 3.79
GC content (%) 53.0
N50 (bp) 8,421
Genome size (bp) 2,741,925

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2428

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1005_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 572.0
PYH2_k127_1005_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 459.0
PYH2_k127_1005_2 ATP10 protein - - - 0.0000000000000000000000000000000001465 142.0
PYH2_k127_1005_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000001123 136.0
PYH2_k127_1005_4 - - - - 0.000000000007864 73.0
PYH2_k127_1005_5 - - - - 0.00000006645 61.0
PYH2_k127_1005_6 dienelactone hydrolase - - - 0.000003459 59.0
PYH2_k127_1014198_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 622.0
PYH2_k127_1014198_1 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 338.0
PYH2_k127_1014198_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000018 282.0
PYH2_k127_1014198_3 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003549 280.0
PYH2_k127_1014198_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004083 273.0
PYH2_k127_1014198_5 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000491 255.0
PYH2_k127_1014198_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008698 252.0
PYH2_k127_1014198_7 cellular response to dsDNA K11211 - 2.7.1.166 0.000000000000000000000000006268 124.0
PYH2_k127_1014198_8 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000001019 113.0
PYH2_k127_1014198_9 Belongs to the UPF0434 family K09791 - - 0.0000005415 51.0
PYH2_k127_1031806_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 619.0
PYH2_k127_1031806_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 423.0
PYH2_k127_1031806_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000007293 259.0
PYH2_k127_1031806_3 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000002889 248.0
PYH2_k127_1031806_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
PYH2_k127_1031806_5 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000001148 172.0
PYH2_k127_1031806_6 Lysin motif K06194 - - 0.000000000000000000000000000000000000001408 157.0
PYH2_k127_1031806_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000001443 149.0
PYH2_k127_1031806_8 Peptidase family M23 - - - 0.00000000000000000000000000000000000004065 150.0
PYH2_k127_1032595_0 BadF BadG BcrA BcrD - - - 0.0 1611.0
PYH2_k127_1032595_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.391e-235 740.0
PYH2_k127_1032595_10 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000000002123 121.0
PYH2_k127_1032595_2 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 384.0
PYH2_k127_1032595_3 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 296.0
PYH2_k127_1032595_4 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002013 252.0
PYH2_k127_1032595_5 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001155 240.0
PYH2_k127_1032595_6 PFAM YicC-like family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000005537 225.0
PYH2_k127_1032595_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000001475 222.0
PYH2_k127_1032595_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000003818 194.0
PYH2_k127_1032595_9 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000000000001218 179.0
PYH2_k127_1042743_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2009.0
PYH2_k127_1042743_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1823.0
PYH2_k127_1042743_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000006336 86.0
PYH2_k127_1042743_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000101 70.0
PYH2_k127_1042743_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000002415 73.0
PYH2_k127_1042743_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000001868 77.0
PYH2_k127_1042743_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.011e-291 911.0
PYH2_k127_1042743_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 312.0
PYH2_k127_1042743_4 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001815 256.0
PYH2_k127_1042743_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001561 224.0
PYH2_k127_1042743_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000005678 213.0
PYH2_k127_1042743_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000001001 209.0
PYH2_k127_1042743_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000002608 158.0
PYH2_k127_1042743_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000001437 150.0
PYH2_k127_1069679_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.342e-202 637.0
PYH2_k127_1069679_1 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 561.0
PYH2_k127_1069679_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 326.0
PYH2_k127_1069679_3 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
PYH2_k127_1069679_4 - - - - 0.000000000000000000000002428 111.0
PYH2_k127_1069679_5 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000005805 103.0
PYH2_k127_1069679_6 - - - - 0.0000000007036 69.0
PYH2_k127_1096765_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 344.0
PYH2_k127_1096765_1 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001016 288.0
PYH2_k127_1096765_10 Septum formation initiator K13052 - - 0.0005673 46.0
PYH2_k127_1096765_2 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000002428 139.0
PYH2_k127_1096765_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000008672 129.0
PYH2_k127_1096765_4 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000003994 127.0
PYH2_k127_1096765_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000001249 120.0
PYH2_k127_1096765_6 - - - - 0.000000000000000005431 98.0
PYH2_k127_1096765_7 Pilus assembly protein, PilP K02665 - - 0.0000000000000002294 86.0
PYH2_k127_1096765_8 PFAM Fimbrial assembly K02663 - - 0.000000000000001351 83.0
PYH2_k127_1096765_9 PFAM helix-turn-helix domain protein - - - 0.000000000000001616 78.0
PYH2_k127_1131684_0 FAD binding domain - - - 0.00000000000000000000000000000000000000006656 168.0
PYH2_k127_1131684_1 NHL repeat - - - 0.0000002535 62.0
PYH2_k127_1131684_2 Ferredoxin-dependent bilin reductase K08101 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0010019,GO:0016491,GO:0016627,GO:0016636,GO:0023052,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050619,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007 1.3.7.4 0.000001313 59.0
PYH2_k127_1131684_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000004044 51.0
PYH2_k127_11340_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 446.0
PYH2_k127_11340_1 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
PYH2_k127_11340_2 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000372 120.0
PYH2_k127_11340_3 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000006912 102.0
PYH2_k127_11340_4 - - - - 0.000000000000004932 81.0
PYH2_k127_115049_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.65e-232 724.0
PYH2_k127_115049_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 351.0
PYH2_k127_115049_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000004051 106.0
PYH2_k127_1151299_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 1.441e-215 679.0
PYH2_k127_1151299_1 cellulose binding K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000001326 234.0
PYH2_k127_1151299_2 Flavodoxin-like fold K00355,K11748 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000001611 212.0
PYH2_k127_1151299_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.000000000000000000000000000000000000000000000000008455 182.0
PYH2_k127_1151299_4 cellulose binding K13735 - - 0.00000000002627 67.0
PYH2_k127_1151299_5 Ribbon-helix-helix domain - - - 0.0008146 43.0
PYH2_k127_1156616_0 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000008667 224.0
PYH2_k127_1156616_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000001438 118.0
PYH2_k127_1156616_2 pilus assembly protein PilW - - - 0.000000000000000004069 93.0
PYH2_k127_1156616_3 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000000003667 75.0
PYH2_k127_1195814_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 2.612e-194 631.0
PYH2_k127_1195814_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 452.0
PYH2_k127_1195814_2 transferase activity, transferring glycosyl groups K14597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 273.0
PYH2_k127_1195814_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000000000000000000000000000000000000000000002157 214.0
PYH2_k127_1195814_4 Acyl-transferase K00655,K14598 - 2.3.1.51 0.000000000000000000000000000000000000000000000001999 181.0
PYH2_k127_1195814_5 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000002194 149.0
PYH2_k127_1195814_6 Subtilase family K13274 - - 0.0001368 47.0
PYH2_k127_1233145_0 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 455.0
PYH2_k127_1233145_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 419.0
PYH2_k127_1233145_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 405.0
PYH2_k127_1233145_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001381 260.0
PYH2_k127_1233145_4 Poly A polymerase, head domain K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000008837 235.0
PYH2_k127_1233145_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000009564 224.0
PYH2_k127_1233145_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002986 202.0
PYH2_k127_1233145_7 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000002284 164.0
PYH2_k127_1233145_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000003752 144.0
PYH2_k127_1233145_9 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000001592 129.0
PYH2_k127_1239313_0 Transglycosylase - - - 4.457e-221 724.0
PYH2_k127_1239313_1 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000005646 212.0
PYH2_k127_1239313_2 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001488 192.0
PYH2_k127_1239313_3 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000002292 79.0
PYH2_k127_1269979_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002449 261.0
PYH2_k127_1269979_1 Hydantoin racemase - - - 0.000000000000000000000000006127 120.0
PYH2_k127_1269979_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000007202 98.0
PYH2_k127_1269979_3 PFAM FecR protein K01387 - 3.4.24.3 0.000003365 58.0
PYH2_k127_1291106_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.843e-309 971.0
PYH2_k127_1291106_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 480.0
PYH2_k127_1291106_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000005371 156.0
PYH2_k127_1291106_3 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000165 115.0
PYH2_k127_1291106_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000142 115.0
PYH2_k127_1291106_5 regulation of DNA repair K03565 - - 0.00000000000000001204 89.0
PYH2_k127_1298953_0 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 507.0
PYH2_k127_1298953_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 376.0
PYH2_k127_1298953_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000009407 221.0
PYH2_k127_1298953_3 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.00000000000000000000000000000001358 136.0
PYH2_k127_1298953_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000007915 126.0
PYH2_k127_1298953_5 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.000000000000000000009335 103.0
PYH2_k127_1298953_6 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.00000000000000001359 85.0
PYH2_k127_1298953_7 cAMP biosynthetic process - - - 0.000000000005352 77.0
PYH2_k127_1298953_8 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000001004 67.0
PYH2_k127_1298953_9 Domain of unknown function (DUF362) - - - 0.0000008438 60.0
PYH2_k127_1306481_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.305e-225 714.0
PYH2_k127_1306481_1 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 368.0
PYH2_k127_1306481_10 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000002273 58.0
PYH2_k127_1306481_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 351.0
PYH2_k127_1306481_3 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000007738 238.0
PYH2_k127_1306481_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001261 239.0
PYH2_k127_1306481_5 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000001954 138.0
PYH2_k127_1306481_6 Fe-S-cluster-containing hydrogenase K00196 - - 0.0000000000000000000306 96.0
PYH2_k127_1306481_7 - - - - 0.000000000000006477 77.0
PYH2_k127_1306481_8 - - - - 0.000000000000679 76.0
PYH2_k127_1306481_9 SMART Elongator protein 3 MiaB NifB - - - 0.0000000003357 66.0
PYH2_k127_1323261_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 581.0
PYH2_k127_1323261_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 416.0
PYH2_k127_1323261_10 denitrification pathway - - - 0.000000000000000002574 94.0
PYH2_k127_1323261_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 278.0
PYH2_k127_1323261_3 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004958 264.0
PYH2_k127_1323261_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000591 211.0
PYH2_k127_1323261_5 Periplasmic Protein - - - 0.0000000000000000000000000000000000000000000000002503 189.0
PYH2_k127_1323261_6 anaerobic respiration - - - 0.000000000000000000000000000000000000000000000001483 195.0
PYH2_k127_1323261_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000001283 145.0
PYH2_k127_1323261_8 amine dehydrogenase activity K21449 - - 0.00000000000000000001245 97.0
PYH2_k127_1323261_9 response regulator receiver K13599 - - 0.00000000000000000005466 99.0
PYH2_k127_1333969_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 415.0
PYH2_k127_1333969_1 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 317.0
PYH2_k127_1333969_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008157 249.0
PYH2_k127_1333969_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
PYH2_k127_1333969_4 ABC-2 family transporter protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000002509 206.0
PYH2_k127_1333969_5 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000003615 179.0
PYH2_k127_1333969_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000001461 156.0
PYH2_k127_1342506_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 424.0
PYH2_k127_1342506_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 347.0
PYH2_k127_1342506_2 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000149 280.0
PYH2_k127_1342506_3 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003676 273.0
PYH2_k127_1342506_4 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003106 259.0
PYH2_k127_1342506_5 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000832 129.0
PYH2_k127_1342506_6 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000002823 110.0
PYH2_k127_1342506_7 - - - - 0.000000000000000000001032 96.0
PYH2_k127_1373027_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 447.0
PYH2_k127_1373027_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000002825 242.0
PYH2_k127_1373027_2 PIN domain - - - 0.0000000000000000000000000000000000000000005136 160.0
PYH2_k127_1373027_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000001918 162.0
PYH2_k127_1373027_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000002489 129.0
PYH2_k127_1373027_5 SpoVT / AbrB like domain - - - 0.00000000000000000007024 91.0
PYH2_k127_1373027_6 CO dehydrogenase flavoprotein domain protein K13481 - 1.17.1.4 0.00073 44.0
PYH2_k127_1396057_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 583.0
PYH2_k127_1396057_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 348.0
PYH2_k127_1396057_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 290.0
PYH2_k127_1396057_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005365 279.0
PYH2_k127_1396057_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
PYH2_k127_1396057_5 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000003397 246.0
PYH2_k127_1396057_6 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000002104 74.0
PYH2_k127_1443185_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 537.0
PYH2_k127_1443185_1 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 451.0
PYH2_k127_1443185_10 - - - - 0.000000000000000000000000000000000003074 147.0
PYH2_k127_1443185_11 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000007704 64.0
PYH2_k127_1443185_12 metallopeptidase activity - - - 0.0000002343 56.0
PYH2_k127_1443185_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 387.0
PYH2_k127_1443185_3 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 381.0
PYH2_k127_1443185_4 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004003 275.0
PYH2_k127_1443185_5 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000001498 218.0
PYH2_k127_1443185_6 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000003678 194.0
PYH2_k127_1443185_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000008837 188.0
PYH2_k127_1443185_8 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000001132 180.0
PYH2_k127_1443185_9 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000001647 178.0
PYH2_k127_1472988_0 Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell - - - 0.00000000000000000000000000000000000753 143.0
PYH2_k127_1472988_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000001176 78.0
PYH2_k127_1472988_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000001654 75.0
PYH2_k127_1477327_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 344.0
PYH2_k127_1477327_1 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000001594 238.0
PYH2_k127_1477327_2 flagellar protein flis K02422 - - 0.00000000000000175 84.0
PYH2_k127_1492194_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 591.0
PYH2_k127_1492194_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 576.0
PYH2_k127_1492194_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 355.0
PYH2_k127_1492194_11 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 344.0
PYH2_k127_1492194_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 310.0
PYH2_k127_1492194_13 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 303.0
PYH2_k127_1492194_14 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 280.0
PYH2_k127_1492194_15 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
PYH2_k127_1492194_16 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000359 248.0
PYH2_k127_1492194_17 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000005579 231.0
PYH2_k127_1492194_18 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000002383 220.0
PYH2_k127_1492194_19 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000001375 204.0
PYH2_k127_1492194_2 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 568.0
PYH2_k127_1492194_20 cellulose binding - - - 0.000000000000000000000000000000000000000006176 167.0
PYH2_k127_1492194_21 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000001541 160.0
PYH2_k127_1492194_22 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000003371 162.0
PYH2_k127_1492194_23 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000002204 145.0
PYH2_k127_1492194_24 Essential cell division protein K03589 - - 0.000000000000000000000000000000002617 140.0
PYH2_k127_1492194_25 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000002978 125.0
PYH2_k127_1492194_26 HD domain - - - 0.0000000000000000000000006488 109.0
PYH2_k127_1492194_27 Cell division protein FtsL - - - 0.0000000007833 66.0
PYH2_k127_1492194_28 4Fe-4S dicluster domain - - - 0.000000002783 60.0
PYH2_k127_1492194_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 531.0
PYH2_k127_1492194_4 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 522.0
PYH2_k127_1492194_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 499.0
PYH2_k127_1492194_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 481.0
PYH2_k127_1492194_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 458.0
PYH2_k127_1492194_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 440.0
PYH2_k127_1492194_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 428.0
PYH2_k127_150924_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 434.0
PYH2_k127_150924_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000008571 239.0
PYH2_k127_150924_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000005677 231.0
PYH2_k127_150924_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001654 183.0
PYH2_k127_150924_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000001404 154.0
PYH2_k127_150924_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002538 124.0
PYH2_k127_150924_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000132 112.0
PYH2_k127_150924_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000101 70.0
PYH2_k127_1566029_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1069.0
PYH2_k127_1566029_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 377.0
PYH2_k127_1566029_10 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.000000000000000000000589 96.0
PYH2_k127_1566029_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 368.0
PYH2_k127_1566029_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 334.0
PYH2_k127_1566029_4 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 330.0
PYH2_k127_1566029_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005118 256.0
PYH2_k127_1566029_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000003717 237.0
PYH2_k127_1566029_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000003537 227.0
PYH2_k127_1566029_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000002296 171.0
PYH2_k127_1566029_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000004886 142.0
PYH2_k127_1573116_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 379.0
PYH2_k127_1573116_1 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000002639 192.0
PYH2_k127_1631068_0 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000003099 193.0
PYH2_k127_1631068_1 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000003278 137.0
PYH2_k127_1631549_0 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
PYH2_k127_1631549_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000009369 241.0
PYH2_k127_1631549_2 diguanylate cyclase - - - 0.0000000000000000000000000004871 116.0
PYH2_k127_1653391_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0 1057.0
PYH2_k127_1653391_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.062e-213 682.0
PYH2_k127_1653391_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 475.0
PYH2_k127_1653391_3 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 392.0
PYH2_k127_1653391_4 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 361.0
PYH2_k127_1653391_5 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 340.0
PYH2_k127_1653391_6 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001262 257.0
PYH2_k127_1653391_7 PFAM histone deacetylase superfamily - - - 0.0000003356 53.0
PYH2_k127_165948_0 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 328.0
PYH2_k127_165948_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000006473 149.0
PYH2_k127_165948_2 FAD linked oxidase domain protein - - - 0.0000000000000000000001323 100.0
PYH2_k127_165948_3 FAD binding domain - - - 0.000000000000000008072 94.0
PYH2_k127_1681766_0 RmlD substrate binding domain K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 407.0
PYH2_k127_1681766_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 404.0
PYH2_k127_1681766_2 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 369.0
PYH2_k127_1681766_3 Cytidylyltransferase K18431 - 2.7.7.82 0.000000000000000000000000000000000000000000000000000000000000000000001086 243.0
PYH2_k127_1681766_4 Bacterial transferase hexapeptide (six repeats) K19429 - - 0.00000000000000000000000000000000000000000000002187 178.0
PYH2_k127_1681766_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000001186 167.0
PYH2_k127_1681766_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000001703 146.0
PYH2_k127_1681766_7 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000009371 117.0
PYH2_k127_1681766_8 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000008108 120.0
PYH2_k127_1681766_9 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000004529 77.0
PYH2_k127_1697405_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 414.0
PYH2_k127_1697405_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002779 252.0
PYH2_k127_1697405_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000009615 189.0
PYH2_k127_173878_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 469.0
PYH2_k127_173878_1 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 331.0
PYH2_k127_173878_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 265.0
PYH2_k127_173878_3 Transcriptional regulatory protein, C terminal - - - 0.0002922 49.0
PYH2_k127_176277_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 587.0
PYH2_k127_176277_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 411.0
PYH2_k127_176277_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 278.0
PYH2_k127_176277_3 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000001725 124.0
PYH2_k127_176277_4 - - - - 0.00000003725 57.0
PYH2_k127_1765063_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 424.0
PYH2_k127_1765063_1 phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000001414 210.0
PYH2_k127_179141_0 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.968e-269 835.0
PYH2_k127_179141_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
PYH2_k127_179141_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000002348 161.0
PYH2_k127_179141_3 Domain of unknown function (DUF4340) - - - 0.00000006991 61.0
PYH2_k127_1804387_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 465.0
PYH2_k127_1804387_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10819 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001595 199.0
PYH2_k127_1879912_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002858 265.0
PYH2_k127_1879912_1 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000004051 195.0
PYH2_k127_1879912_2 - - - - 0.0000000000000000001334 98.0
PYH2_k127_1935873_0 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 295.0
PYH2_k127_1935873_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000002686 153.0
PYH2_k127_1935873_2 histidine kinase A domain protein - - - 0.00000000000000000000000000004282 134.0
PYH2_k127_1935873_3 hydrogenase maturation protease K03605 - - 0.000000000503 66.0
PYH2_k127_1949905_0 hydrogenase large subunit K06281 - 1.12.99.6 5.358e-204 644.0
PYH2_k127_1949905_1 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 506.0
PYH2_k127_1949905_10 Sh3 type 3 domain protein - - - 0.0000000000000000000000001159 122.0
PYH2_k127_1949905_11 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000009845 118.0
PYH2_k127_1949905_12 cheY-homologous receiver domain K07658 - - 0.00000000000000000000001347 104.0
PYH2_k127_1949905_13 Domain of unknown function (DUF1330) - - - 0.0000000000000000000006712 98.0
PYH2_k127_1949905_14 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000004944 52.0
PYH2_k127_1949905_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 375.0
PYH2_k127_1949905_3 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 329.0
PYH2_k127_1949905_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000006037 228.0
PYH2_k127_1949905_5 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000002592 207.0
PYH2_k127_1949905_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000008151 194.0
PYH2_k127_1949905_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000006761 188.0
PYH2_k127_1949905_8 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000008597 156.0
PYH2_k127_1949905_9 formate dehydrogenase K00127 - - 0.00000000000000000000000000000003424 136.0
PYH2_k127_201546_0 Thioredoxin - - - 0.000000000000000000000279 102.0
PYH2_k127_201546_1 Belongs to the Nudix hydrolase family - - - 0.0000000000000000001592 94.0
PYH2_k127_2026457_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 388.0
PYH2_k127_2026457_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
PYH2_k127_2026457_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 275.0
PYH2_k127_2026457_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000003316 211.0
PYH2_k127_2116013_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1432.0
PYH2_k127_2116013_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K18847 - 2.1.2.1,2.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 601.0
PYH2_k127_2116013_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 599.0
PYH2_k127_2116013_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 587.0
PYH2_k127_2116013_4 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 480.0
PYH2_k127_2116013_5 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000006933 148.0
PYH2_k127_2116013_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000001852 109.0
PYH2_k127_2120588_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 404.0
PYH2_k127_2120588_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 294.0
PYH2_k127_2120588_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000002633 209.0
PYH2_k127_2120588_3 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000001747 186.0
PYH2_k127_2120588_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000002855 60.0
PYH2_k127_2150431_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 340.0
PYH2_k127_2150431_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
PYH2_k127_2150431_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 293.0
PYH2_k127_2150431_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000001053 160.0
PYH2_k127_2150431_4 domain protein - - - 0.00000000002599 75.0
PYH2_k127_2150431_5 PFAM glycosyl transferase family 9 K02843 - - 0.000000008847 63.0
PYH2_k127_2151196_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 610.0
PYH2_k127_2151196_1 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 385.0
PYH2_k127_2151196_10 heat shock protein binding - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.0000000000000000000000000000004163 134.0
PYH2_k127_2151196_11 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000006202 119.0
PYH2_k127_2151196_12 - - - - 0.00000000000000003792 87.0
PYH2_k127_2151196_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 351.0
PYH2_k127_2151196_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 322.0
PYH2_k127_2151196_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 319.0
PYH2_k127_2151196_5 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 297.0
PYH2_k127_2151196_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 288.0
PYH2_k127_2151196_7 PFAM regulatory protein TetR K13770 - - 0.00000000000000000000000000000000000000000000000000000000000000000004057 237.0
PYH2_k127_2151196_8 protein N-acetylglucosaminyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001241 226.0
PYH2_k127_2151196_9 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000004232 191.0
PYH2_k127_2156135_0 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 435.0
PYH2_k127_2156135_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 366.0
PYH2_k127_2156135_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000001195 164.0
PYH2_k127_216096_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 381.0
PYH2_k127_216096_1 - - - - 0.000000000001438 68.0
PYH2_k127_216601_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009762 264.0
PYH2_k127_216601_1 Pyridoxamine 5'-phosphate - - - 0.000000000000256 77.0
PYH2_k127_216601_2 Pyridoxamine 5'-phosphate - - - 0.0000000002139 70.0
PYH2_k127_216601_3 lyase activity K01387,K03301 - 3.4.24.3 0.000000002155 69.0
PYH2_k127_216601_4 - - - - 0.00001617 55.0
PYH2_k127_2188018_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 571.0
PYH2_k127_2188018_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 301.0
PYH2_k127_2188018_2 COGs COG1150 Heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000006975 170.0
PYH2_k127_2201736_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 5.759e-200 640.0
PYH2_k127_2201736_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 456.0
PYH2_k127_2201736_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 423.0
PYH2_k127_2201736_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 302.0
PYH2_k127_2201736_4 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000001426 207.0
PYH2_k127_2201736_5 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000007869 141.0
PYH2_k127_2201736_6 tolerance protein K01733,K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 4.2.3.1 0.000000000000000000000003579 105.0
PYH2_k127_2201736_7 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000305 89.0
PYH2_k127_2201736_8 4Fe-4S binding domain K12143 - - 0.00000000000006125 79.0
PYH2_k127_2201736_9 Sporulation related domain - - - 0.00000000002393 72.0
PYH2_k127_2249254_0 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 535.0
PYH2_k127_2249254_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 421.0
PYH2_k127_2249254_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 317.0
PYH2_k127_2249254_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 304.0
PYH2_k127_2289829_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 491.0
PYH2_k127_2289829_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 490.0
PYH2_k127_2289829_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 362.0
PYH2_k127_2289829_3 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000001081 169.0
PYH2_k127_2289829_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000002571 110.0
PYH2_k127_2289829_5 4Fe-4S dicluster domain - - - 0.0000000000000000000008082 98.0
PYH2_k127_2289829_7 FAD binding domain - - - 0.000004009 57.0
PYH2_k127_2289829_8 - - - - 0.000004854 56.0
PYH2_k127_2290028_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000003158 223.0
PYH2_k127_2290028_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000001009 180.0
PYH2_k127_2316410_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 612.0
PYH2_k127_2316410_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000002047 209.0
PYH2_k127_2316410_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000001346 126.0
PYH2_k127_2316410_3 Lipopolysaccharide-assembly - - - 0.00000000000000005932 87.0
PYH2_k127_2316410_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000008633 65.0
PYH2_k127_2389525_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 426.0
PYH2_k127_2389525_1 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
PYH2_k127_2389525_10 Carbon-nitrogen hydrolase - - - 0.0000000000000000000229 103.0
PYH2_k127_2389525_11 Amidohydrolase K07045 - - 0.0000000000000000001472 100.0
PYH2_k127_2389525_12 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000002518 85.0
PYH2_k127_2389525_13 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000001195 77.0
PYH2_k127_2389525_14 Sh3 type 3 domain protein - - - 0.0000007341 62.0
PYH2_k127_2389525_15 Belongs to the HY2 family K05369 - 1.3.7.2 0.00002928 55.0
PYH2_k127_2389525_2 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 308.0
PYH2_k127_2389525_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000205 289.0
PYH2_k127_2389525_4 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000002956 212.0
PYH2_k127_2389525_5 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000001006 206.0
PYH2_k127_2389525_6 FAD binding domain - - - 0.000000000000000000000000000000000000000000000003718 189.0
PYH2_k127_2389525_7 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000003394 171.0
PYH2_k127_2389525_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000001628 145.0
PYH2_k127_2389525_9 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000003211 119.0
PYH2_k127_2393954_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 409.0
PYH2_k127_2393954_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 357.0
PYH2_k127_2399786_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 2.718e-253 809.0
PYH2_k127_2399786_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000003066 204.0
PYH2_k127_2399786_2 Chlorophyllase enzyme - - - 0.00000000000000000000000203 116.0
PYH2_k127_2405200_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 484.0
PYH2_k127_2405200_1 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 330.0
PYH2_k127_2405200_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 313.0
PYH2_k127_2405200_3 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000006592 194.0
PYH2_k127_2405200_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000001652 160.0
PYH2_k127_2405200_5 Class III cytochrome C family - - - 0.0000000000000000002817 95.0
PYH2_k127_2438898_0 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 8.387e-242 762.0
PYH2_k127_2438898_1 4Fe-4S dicluster domain - - - 8.381e-227 721.0
PYH2_k127_2438898_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 554.0
PYH2_k127_2438898_3 Molybdopterin oxidoreductase Fe4S4 domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 471.0
PYH2_k127_2438898_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 411.0
PYH2_k127_2438898_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000008329 176.0
PYH2_k127_2438898_6 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000006663 134.0
PYH2_k127_2452105_0 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 325.0
PYH2_k127_2452105_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005448 256.0
PYH2_k127_2452105_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000728 254.0
PYH2_k127_2452105_3 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000958 154.0
PYH2_k127_2452105_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000008536 119.0
PYH2_k127_2452105_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000001576 74.0
PYH2_k127_2452105_6 - - - - 0.0003502 49.0
PYH2_k127_2452535_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 554.0
PYH2_k127_2452535_1 4 iron, 4 sulfur cluster binding K18356 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000001678 241.0
PYH2_k127_2452535_2 Involved in the tonB-independent uptake of proteins K13669 - - 0.0002134 53.0
PYH2_k127_2454395_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 400.0
PYH2_k127_2454395_1 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 342.0
PYH2_k127_2454395_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 333.0
PYH2_k127_2454395_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000245 225.0
PYH2_k127_2454395_4 - - - - 0.0002215 52.0
PYH2_k127_2460700_0 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin K05370 - 1.3.7.3 0.00001725 53.0
PYH2_k127_2476668_0 Diguanylate cyclase K21084 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000008869 215.0
PYH2_k127_2476668_1 FAD binding domain - - - 0.0000000000000000000000000000001107 139.0
PYH2_k127_2476668_2 MORN repeat variant - - - 0.00000000000001898 78.0
PYH2_k127_2492034_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 458.0
PYH2_k127_2492034_1 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 368.0
PYH2_k127_2492034_2 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003136 268.0
PYH2_k127_2492034_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000001025 85.0
PYH2_k127_2538592_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 359.0
PYH2_k127_2538592_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 331.0
PYH2_k127_2538592_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000007083 171.0
PYH2_k127_2538592_3 - - - - 0.0000000000000000000000000000000000000004791 167.0
PYH2_k127_2538592_4 Acyltransferase family - - - 0.000000000000000000000000000000000000002198 162.0
PYH2_k127_2538592_5 - - - - 0.00000000000000000000002488 115.0
PYH2_k127_2538592_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000003749 59.0
PYH2_k127_2553401_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.404e-207 660.0
PYH2_k127_2553401_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 360.0
PYH2_k127_2553401_2 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000008086 146.0
PYH2_k127_2553401_3 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.000000000000000000000000000000006961 134.0
PYH2_k127_2553401_4 chlorophyllide reductase subunit Z K11335 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000001315 141.0
PYH2_k127_2563460_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 6.545e-252 788.0
PYH2_k127_2563460_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.105e-221 694.0
PYH2_k127_2563460_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000002285 82.0
PYH2_k127_2563460_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 573.0
PYH2_k127_2563460_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 421.0
PYH2_k127_2563460_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 304.0
PYH2_k127_2563460_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000001326 241.0
PYH2_k127_2563460_6 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000008491 224.0
PYH2_k127_2563460_7 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
PYH2_k127_2563460_8 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000844 184.0
PYH2_k127_2563460_9 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000004087 177.0
PYH2_k127_2570650_0 NHL repeat - - - 0.0000000000000000000000000000000000000000006468 171.0
PYH2_k127_2570650_1 amine dehydrogenase activity - - - 0.00000002173 66.0
PYH2_k127_2570650_2 Belongs to the peptidase S8 family K14645 - - 0.000144 54.0
PYH2_k127_2582502_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 349.0
PYH2_k127_2582502_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000008135 251.0
PYH2_k127_2582502_2 Histidine kinase - - - 0.000000008699 70.0
PYH2_k127_2582502_3 Dihydrodipicolinate synthetase family - - - 0.000009598 49.0
PYH2_k127_2587851_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 554.0
PYH2_k127_2587851_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 342.0
PYH2_k127_2593463_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000005419 173.0
PYH2_k127_2593463_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000001057 153.0
PYH2_k127_2593463_2 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000000000000000000000475 122.0
PYH2_k127_2593463_3 - - - - 0.0000006379 61.0
PYH2_k127_263368_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 593.0
PYH2_k127_263368_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 435.0
PYH2_k127_263368_2 PFAM alpha beta hydrolase fold K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000003381 185.0
PYH2_k127_263368_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.0000000000000000000000000000000000000000000000186 181.0
PYH2_k127_263368_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000002828 173.0
PYH2_k127_2633991_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 321.0
PYH2_k127_2633991_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000007266 125.0
PYH2_k127_2633991_2 methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.00000000000000001522 92.0
PYH2_k127_2638887_0 PFAM oxidoreductase nitrogenase component 1 K02586 - 1.18.6.1 0.000000000000000000001058 108.0
PYH2_k127_2638887_1 Uncharacterised ArCR, COG2043 - - - 0.0000000000008634 77.0
PYH2_k127_2641902_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 491.0
PYH2_k127_2641902_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 304.0
PYH2_k127_2641902_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 278.0
PYH2_k127_2641902_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
PYH2_k127_2641902_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000002867 164.0
PYH2_k127_2641902_5 DoxX - - - 0.00000000002992 70.0
PYH2_k127_2641902_6 Rhodanese Homology Domain - - - 0.0000000002147 66.0
PYH2_k127_2641902_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K03500 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.1.176,2.1.2.9 0.000003583 49.0
PYH2_k127_2648899_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000002084 175.0
PYH2_k127_2648899_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000001581 162.0
PYH2_k127_2648899_2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K16213 - 5.1.3.11 0.00000008534 64.0
PYH2_k127_2688131_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 519.0
PYH2_k127_2688131_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000218 194.0
PYH2_k127_2688131_2 PFAM OsmC family protein - - - 0.0000000000000000000000000000008376 131.0
PYH2_k127_2688131_3 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000032 83.0
PYH2_k127_2688419_0 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 606.0
PYH2_k127_2688419_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000007374 106.0
PYH2_k127_2688419_2 Belongs to the HY2 family K05369 - 1.3.7.2 0.00005483 53.0
PYH2_k127_2690864_0 Acyl-CoA synthetase (NDP forming) K09181 - - 5.927e-239 757.0
PYH2_k127_2690864_1 metallopeptidase activity K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 496.0
PYH2_k127_2690864_2 Rubredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 300.0
PYH2_k127_2690864_3 DRTGG domain K13788 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 299.0
PYH2_k127_2690864_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000002725 202.0
PYH2_k127_2690864_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000007306 78.0
PYH2_k127_276521_0 Bacterial regulatory protein, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 524.0
PYH2_k127_276521_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 511.0
PYH2_k127_276521_2 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 431.0
PYH2_k127_276521_3 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 338.0
PYH2_k127_276521_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000163 235.0
PYH2_k127_276521_5 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000001182 189.0
PYH2_k127_2774982_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.907e-264 824.0
PYH2_k127_2774982_1 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 309.0
PYH2_k127_2774982_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000009826 267.0
PYH2_k127_2774982_3 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005756 257.0
PYH2_k127_2774982_4 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000214 192.0
PYH2_k127_2774982_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000005574 121.0
PYH2_k127_277543_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 591.0
PYH2_k127_277543_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000006115 192.0
PYH2_k127_277543_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000004109 107.0
PYH2_k127_277543_3 PFAM oxidoreductase nitrogenase, component 1 K02586 - 1.18.6.1 0.000000000000002461 86.0
PYH2_k127_2842909_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1065.0
PYH2_k127_2842909_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 362.0
PYH2_k127_2842909_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 308.0
PYH2_k127_2842909_3 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 304.0
PYH2_k127_2842909_4 AIR synthase related protein, C-terminal domain K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000003111 273.0
PYH2_k127_2842909_5 - - - - 0.000000000000000000000000000000000001177 144.0
PYH2_k127_2842909_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000001022 128.0
PYH2_k127_2842909_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000002391 78.0
PYH2_k127_2858552_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 584.0
PYH2_k127_2858552_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 474.0
PYH2_k127_2858552_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 464.0
PYH2_k127_2858552_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 416.0
PYH2_k127_2858552_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000003088 83.0
PYH2_k127_2858552_6 - - - - 0.000005802 53.0
PYH2_k127_2863630_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1029.0
PYH2_k127_2863630_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 423.0
PYH2_k127_2863630_10 - - - - 0.000000000000001168 80.0
PYH2_k127_2863630_11 4Fe-4S binding domain - - - 0.0000001673 55.0
PYH2_k127_2863630_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 371.0
PYH2_k127_2863630_3 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 361.0
PYH2_k127_2863630_4 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 295.0
PYH2_k127_2863630_5 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000003986 241.0
PYH2_k127_2863630_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000001151 219.0
PYH2_k127_2863630_7 - - - - 0.000000000000000000000000000000000000000000000000000000001313 205.0
PYH2_k127_2863630_8 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000000000000000001424 153.0
PYH2_k127_2863630_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000004287 107.0
PYH2_k127_2887623_0 Pyruvate formate lyase-like - - - 3.404e-214 692.0
PYH2_k127_2887623_1 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 511.0
PYH2_k127_2887623_2 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 413.0
PYH2_k127_2887623_3 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000009997 229.0
PYH2_k127_2887623_4 FAD dependent oxidoreductase K00313 - - 0.00000000001752 77.0
PYH2_k127_2887623_5 PFAM 4Fe-4S ferredoxin - - - 0.00000000004992 67.0
PYH2_k127_2887623_6 Phytochromobilin ferredoxin oxidoreductase K08101 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0010019,GO:0016491,GO:0016627,GO:0016636,GO:0023052,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050619,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007 1.3.7.4 0.000001278 59.0
PYH2_k127_2905376_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 535.0
PYH2_k127_2905376_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 321.0
PYH2_k127_2905376_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000004237 228.0
PYH2_k127_2910760_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 471.0
PYH2_k127_2910760_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000004726 224.0
PYH2_k127_2910760_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000208 94.0
PYH2_k127_2910760_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000002387 79.0
PYH2_k127_2910760_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000001978 72.0
PYH2_k127_2910760_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0002575 49.0
PYH2_k127_293245_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 513.0
PYH2_k127_293245_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000003436 238.0
PYH2_k127_2955579_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 1.733e-244 766.0
PYH2_k127_2955579_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 616.0
PYH2_k127_2955579_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 438.0
PYH2_k127_2955579_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000002322 217.0
PYH2_k127_2955579_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000005929 179.0
PYH2_k127_2955579_5 Thiamine-binding protein - - - 0.00000000000000000000000006564 113.0
PYH2_k127_3020936_0 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 2.918e-229 739.0
PYH2_k127_3020936_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 319.0
PYH2_k127_3020936_2 Conserved protein K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 292.0
PYH2_k127_3020936_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000006395 208.0
PYH2_k127_3020936_4 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000681 172.0
PYH2_k127_3020936_5 Tetratricopeptide repeat - - - 0.0000000000000004558 85.0
PYH2_k127_3020936_6 PFAM Rubrerythrin - - - 0.00000002045 55.0
PYH2_k127_3034801_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.539e-268 837.0
PYH2_k127_3034801_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 315.0
PYH2_k127_3034801_2 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001315 240.0
PYH2_k127_3034801_3 PFAM Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
PYH2_k127_3034801_4 beta-lactamase superfamily i K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000133 213.0
PYH2_k127_3034801_5 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.000000000000000000000000000000000000000000003805 177.0
PYH2_k127_3034801_6 peroxiredoxin activity - - - 0.000000000000000000000002146 109.0
PYH2_k127_3034801_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000751 70.0
PYH2_k127_3053004_0 Uncharacterized protein family UPF0004 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 330.0
PYH2_k127_3053004_1 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 271.0
PYH2_k127_3053004_2 Flavodoxin domain K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000631 219.0
PYH2_k127_305764_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 472.0
PYH2_k127_305764_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
PYH2_k127_305764_2 Cytochrome c - - - 0.00000000000000000000000008614 115.0
PYH2_k127_3084361_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000001404 240.0
PYH2_k127_3084361_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000006598 237.0
PYH2_k127_3084361_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000008747 137.0
PYH2_k127_3084361_3 Type IV pilus biogenesis stability protein PilW - - - 0.00007612 53.0
PYH2_k127_3116668_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 540.0
PYH2_k127_3116668_1 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 399.0
PYH2_k127_3116668_10 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000002463 157.0
PYH2_k127_3116668_11 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000001137 145.0
PYH2_k127_3116668_12 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000002621 146.0
PYH2_k127_3116668_13 - - - - 0.000000000000000000000000000003501 129.0
PYH2_k127_3116668_14 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000115 112.0
PYH2_k127_3116668_15 - - - - 0.0000000000000000000000001831 114.0
PYH2_k127_3116668_16 monooxygenase activity - - - 0.0000000000001523 74.0
PYH2_k127_3116668_17 TonB C terminal K03832 - - 0.000000003358 68.0
PYH2_k127_3116668_18 C4-type zinc ribbon domain K07164 - - 0.000002829 53.0
PYH2_k127_3116668_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 302.0
PYH2_k127_3116668_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 299.0
PYH2_k127_3116668_4 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
PYH2_k127_3116668_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000003889 206.0
PYH2_k127_3116668_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000004238 182.0
PYH2_k127_3116668_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000002534 178.0
PYH2_k127_3116668_8 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000004617 160.0
PYH2_k127_3116668_9 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000001178 156.0
PYH2_k127_3126226_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.0 1023.0
PYH2_k127_3126226_1 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 414.0
PYH2_k127_3126226_2 Carbon starvation protein K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 363.0
PYH2_k127_3126226_3 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000009448 205.0
PYH2_k127_3126226_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000009328 201.0
PYH2_k127_3126898_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 498.0
PYH2_k127_3126898_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 392.0
PYH2_k127_3126898_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 379.0
PYH2_k127_3126898_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000004192 197.0
PYH2_k127_3126898_4 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000002542 190.0
PYH2_k127_3126898_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000003454 141.0
PYH2_k127_3126898_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000392 126.0
PYH2_k127_3127143_0 PFAM ABC transporter K06158 - - 1.589e-238 751.0
PYH2_k127_3127143_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.029e-220 694.0
PYH2_k127_3127143_10 Belongs to the ParA family K04562 - - 0.000000000005822 76.0
PYH2_k127_3127143_11 - - - - 0.00000000003763 69.0
PYH2_k127_3127143_12 Ribbon-helix-helix domain - - - 0.000001948 51.0
PYH2_k127_3127143_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 498.0
PYH2_k127_3127143_3 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 503.0
PYH2_k127_3127143_4 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 326.0
PYH2_k127_3127143_5 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 295.0
PYH2_k127_3127143_6 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000009553 228.0
PYH2_k127_3127143_7 sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000002302 214.0
PYH2_k127_3127143_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000001325 179.0
PYH2_k127_3127143_9 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000002095 95.0
PYH2_k127_3130217_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 453.0
PYH2_k127_3130217_1 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 398.0
PYH2_k127_3130217_10 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000004978 102.0
PYH2_k127_3130217_11 Tetratricopeptide repeat - - - 0.000000000000000007083 88.0
PYH2_k127_3130217_12 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.000000000000001817 89.0
PYH2_k127_3130217_13 peptidyl-tyrosine sulfation K07114 - - 0.00000000000009652 81.0
PYH2_k127_3130217_15 Oxygen tolerance - - - 0.0001379 53.0
PYH2_k127_3130217_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 376.0
PYH2_k127_3130217_3 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 365.0
PYH2_k127_3130217_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 351.0
PYH2_k127_3130217_5 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 343.0
PYH2_k127_3130217_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 333.0
PYH2_k127_3130217_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 308.0
PYH2_k127_3130217_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000349 162.0
PYH2_k127_3130217_9 DDE superfamily endonuclease K07494 - - 0.00000000000000000000000000002816 117.0
PYH2_k127_3145307_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.832e-216 687.0
PYH2_k127_3145307_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 349.0
PYH2_k127_3157685_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.029e-199 640.0
PYH2_k127_3157685_1 PFAM CobN Magnesium Chelatase K02230 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001332 254.0
PYH2_k127_3157685_2 Psort location Cytoplasmic, score 9.98 K05796 - - 0.00000000002543 76.0
PYH2_k127_3157685_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000002904 67.0
PYH2_k127_3157685_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000001309 63.0
PYH2_k127_3210583_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
PYH2_k127_3210583_1 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 296.0
PYH2_k127_3210583_2 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000002895 215.0
PYH2_k127_3210583_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000001091 155.0
PYH2_k127_3221474_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 568.0
PYH2_k127_3221474_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 427.0
PYH2_k127_3221474_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000134 223.0
PYH2_k127_3221474_3 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000001001 149.0
PYH2_k127_3221474_4 - - - - 0.00000007274 57.0
PYH2_k127_3221474_5 MORN repeat variant - - - 0.000002759 55.0
PYH2_k127_3221981_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.265e-301 956.0
PYH2_k127_3221981_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.781e-213 669.0
PYH2_k127_3221981_10 Domain of unknown function (DUF4410) - - - 0.00000000000000000000003298 108.0
PYH2_k127_3221981_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 4.868e-195 613.0
PYH2_k127_3221981_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 550.0
PYH2_k127_3221981_4 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 392.0
PYH2_k127_3221981_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 365.0
PYH2_k127_3221981_6 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 348.0
PYH2_k127_3221981_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000003245 230.0
PYH2_k127_3221981_8 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000000001773 187.0
PYH2_k127_3221981_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000005448 164.0
PYH2_k127_3310307_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000006786 205.0
PYH2_k127_3310307_1 Flavodoxin-like fold - - - 0.0000000000000000000143 99.0
PYH2_k127_3310307_2 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.00000000000222 70.0
PYH2_k127_3310307_3 methyltransferase - - - 0.00000000007374 69.0
PYH2_k127_3310307_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002552 60.0
PYH2_k127_3349642_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 458.0
PYH2_k127_3349642_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 304.0
PYH2_k127_3349642_2 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000209 170.0
PYH2_k127_3349642_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000001142 107.0
PYH2_k127_3349642_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000003621 69.0
PYH2_k127_3379295_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 475.0
PYH2_k127_3379295_1 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000001921 187.0
PYH2_k127_3379295_2 PFAM ResB family protein K07399 - - 0.0000000000002116 83.0
PYH2_k127_340339_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 8.07e-209 658.0
PYH2_k127_340339_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 474.0
PYH2_k127_340339_2 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000008285 246.0
PYH2_k127_340339_3 - - - - 0.0000000000000001699 81.0
PYH2_k127_340339_4 Collagenase K01387 GO:0005575,GO:0005576 3.4.24.3 0.000000000006208 78.0
PYH2_k127_340339_5 OsmC-like protein - - - 0.0000003559 55.0
PYH2_k127_3451450_0 Arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 393.0
PYH2_k127_3451450_1 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 371.0
PYH2_k127_3451450_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002734 282.0
PYH2_k127_3451450_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000005522 245.0
PYH2_k127_3465190_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.436e-276 865.0
PYH2_k127_3465190_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 236.0
PYH2_k127_3465190_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000001915 205.0
PYH2_k127_3465190_3 - - - - 0.000000001897 60.0
PYH2_k127_3495158_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.796e-209 658.0
PYH2_k127_3495158_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 308.0
PYH2_k127_3495158_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000004076 149.0
PYH2_k127_3495158_11 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000009912 147.0
PYH2_k127_3495158_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000001575 130.0
PYH2_k127_3495158_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001421 106.0
PYH2_k127_3495158_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000004289 107.0
PYH2_k127_3495158_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003748 76.0
PYH2_k127_3495158_16 Ribosomal protein L36 K02919 - - 0.000000000001872 67.0
PYH2_k127_3495158_17 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001937 69.0
PYH2_k127_3495158_18 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000003068 68.0
PYH2_k127_3495158_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 289.0
PYH2_k127_3495158_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 288.0
PYH2_k127_3495158_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
PYH2_k127_3495158_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
PYH2_k127_3495158_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003467 201.0
PYH2_k127_3495158_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001839 202.0
PYH2_k127_3495158_8 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000001944 186.0
PYH2_k127_3495158_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000002891 173.0
PYH2_k127_35179_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 469.0
PYH2_k127_35179_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 363.0
PYH2_k127_35179_2 - - - - 0.000000000000000000000000000000000000000000000000000001229 201.0
PYH2_k127_35179_3 epimerase - - - 0.00000000000000000000000000000000000000000000000004872 183.0
PYH2_k127_356311_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1171.0
PYH2_k127_356311_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1146.0
PYH2_k127_356311_10 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 261.0
PYH2_k127_356311_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
PYH2_k127_356311_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000001939 231.0
PYH2_k127_356311_13 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000001547 213.0
PYH2_k127_356311_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000001331 188.0
PYH2_k127_356311_15 helicase superfamily c-terminal domain K06877 - - 0.000000000000000000000000000000000000000000085 166.0
PYH2_k127_356311_16 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000000000000000001962 143.0
PYH2_k127_356311_17 YacP-like NYN domain K06962 - - 0.0000000000000000000000000000000009996 138.0
PYH2_k127_356311_18 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000003504 139.0
PYH2_k127_356311_19 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.000000000000000000000000263 123.0
PYH2_k127_356311_2 4Fe-4S binding domain K02572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 521.0
PYH2_k127_356311_20 PTS HPr component phosphorylation site K11189 - - 0.00000000000000005802 83.0
PYH2_k127_356311_22 Bacterial SH3 domain homologues K07184 - - 0.00000000001723 72.0
PYH2_k127_356311_3 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 488.0
PYH2_k127_356311_4 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 475.0
PYH2_k127_356311_5 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 404.0
PYH2_k127_356311_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 389.0
PYH2_k127_356311_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 335.0
PYH2_k127_356311_8 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001425 288.0
PYH2_k127_356311_9 Glycosyltransferase Family 4 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006895 294.0
PYH2_k127_3585479_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 421.0
PYH2_k127_3585479_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000573 248.0
PYH2_k127_36432_0 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 561.0
PYH2_k127_36432_1 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000395 167.0
PYH2_k127_36432_2 - - - - 0.000000000000000004335 89.0
PYH2_k127_36432_3 Uncharacterised ArCR, COG2043 - - - 0.0000000000001445 79.0
PYH2_k127_36432_4 PFAM FecR protein K01387 - 3.4.24.3 0.0000000000008795 81.0
PYH2_k127_3703989_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 1402.0
PYH2_k127_3703989_1 - - - - 0.0000002811 61.0
PYH2_k127_371622_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 496.0
PYH2_k127_371622_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000002044 189.0
PYH2_k127_371622_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000001473 141.0
PYH2_k127_3770446_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 405.0
PYH2_k127_3770446_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000819 276.0
PYH2_k127_3770446_10 HEAT repeat - - - 0.00000634 57.0
PYH2_k127_3770446_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
PYH2_k127_3770446_3 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000006867 206.0
PYH2_k127_3770446_4 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000004285 182.0
PYH2_k127_3770446_5 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000001366 184.0
PYH2_k127_3770446_6 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000209 168.0
PYH2_k127_3770446_7 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.00000000000000000000000000000000000000009463 160.0
PYH2_k127_3770446_8 DNA binding domain, excisionase family - - - 0.0000000000002489 71.0
PYH2_k127_3770446_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000001019 69.0
PYH2_k127_3784880_0 Belongs to the GPI family K01810 - 5.3.1.9 2.504e-291 901.0
PYH2_k127_3784880_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.03e-206 652.0
PYH2_k127_3784880_2 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000003663 217.0
PYH2_k127_3784880_3 Cytochrome C biogenesis protein K06196 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000004188 89.0
PYH2_k127_3790294_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 401.0
PYH2_k127_3790294_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003241 278.0
PYH2_k127_3790294_2 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000009432 223.0
PYH2_k127_3790294_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000003554 196.0
PYH2_k127_3790294_4 Jag_N K06346 - - 0.0000000000000000000000000000000000000000000000005887 183.0
PYH2_k127_3805160_0 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 385.0
PYH2_k127_3805160_1 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000001086 226.0
PYH2_k127_3805160_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K18478 - 2.7.1.15,2.7.1.184 0.00000000000000000000001566 105.0
PYH2_k127_3805160_3 lactoylglutathione lyase activity - - - 0.0000000000000000009136 91.0
PYH2_k127_3805160_4 - - - - 0.0000002817 62.0
PYH2_k127_3830420_0 transferase activity, transferring glycosyl groups K07011 - - 0.000000000000000000000000000000000000000000000000000000000000001212 234.0
PYH2_k127_3830420_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000002677 194.0
PYH2_k127_3830420_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000002418 190.0
PYH2_k127_3830420_3 transferase activity, transferring glycosyl groups K07011,K13659 - 2.4.1.264 0.000000000000000000000000000000000000000000003776 178.0
PYH2_k127_3830420_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000005262 171.0
PYH2_k127_3830420_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000002815 132.0
PYH2_k127_3830420_6 PFAM Glycosyl transferase family 2 K07011,K20444 - - 0.000000000000000000000000000000006005 137.0
PYH2_k127_3830420_7 O-methyltransferase activity - - - 0.000000000000000000000001181 113.0
PYH2_k127_3830420_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000001357 84.0
PYH2_k127_3840709_0 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 332.0
PYH2_k127_3840709_1 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
PYH2_k127_3840709_2 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000006225 197.0
PYH2_k127_3840709_3 Multidrug Resistance protein K03297 - - 0.00000000002333 70.0
PYH2_k127_3843709_0 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 346.0
PYH2_k127_3843709_1 Dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 319.0
PYH2_k127_3843709_2 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 321.0
PYH2_k127_3843709_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002918 251.0
PYH2_k127_3843709_4 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000002141 141.0
PYH2_k127_3843709_5 P60 family K21471 - - 0.000000000000000000000000216 116.0
PYH2_k127_3843709_6 Bacterial regulatory proteins, tetR family - - - 0.000000007639 64.0
PYH2_k127_3846992_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 498.0
PYH2_k127_3846992_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000009396 67.0
PYH2_k127_3862452_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 482.0
PYH2_k127_3862452_1 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000006654 148.0
PYH2_k127_3862452_2 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000008 141.0
PYH2_k127_3862452_3 Tetratricopeptide repeat - - - 0.00000000000000000128 93.0
PYH2_k127_3862452_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000192 67.0
PYH2_k127_3871220_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 327.0
PYH2_k127_3871220_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000005005 228.0
PYH2_k127_3871220_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
PYH2_k127_3871220_3 Exporters of the RND superfamily K07003 - - 0.0000000000000000001092 94.0
PYH2_k127_3874608_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 426.0
PYH2_k127_3874608_1 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 418.0
PYH2_k127_3874608_2 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 347.0
PYH2_k127_3874608_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 362.0
PYH2_k127_3874608_4 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000006601 227.0
PYH2_k127_3874608_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000001041 111.0
PYH2_k127_3874608_6 - - - - 0.0000001116 53.0
PYH2_k127_3881425_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 511.0
PYH2_k127_3881425_1 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 366.0
PYH2_k127_3881425_2 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 323.0
PYH2_k127_3881425_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000001974 225.0
PYH2_k127_3881425_4 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.000000000000000000000000000000000000000000000000000006244 199.0
PYH2_k127_3881425_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000154 186.0
PYH2_k127_3881425_6 Cytochrome c biogenesis protein transmembrane region K06196 - - 0.00000003949 64.0
PYH2_k127_3881425_7 Tetratricopeptide repeat - - - 0.000005085 58.0
PYH2_k127_3886649_0 TIGRFAM phosphonopyruvate decarboxylase-related protein K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 561.0
PYH2_k127_3886649_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000345 182.0
PYH2_k127_3886649_2 - - - - 0.000000000000000000000000346 110.0
PYH2_k127_3893133_0 Ferrous iron transport protein B C terminus K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 423.0
PYH2_k127_3893133_1 PFAM multicopper oxidase type K04753,K08100,K14588 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 402.0
PYH2_k127_3897608_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.82e-246 777.0
PYH2_k127_3897608_1 Oxidoreductase NAD-binding domain K17995 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 313.0
PYH2_k127_3897608_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 298.0
PYH2_k127_3897608_3 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002554 275.0
PYH2_k127_3897608_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000001579 203.0
PYH2_k127_3897608_5 PFAM Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000005153 201.0
PYH2_k127_3897608_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000002102 178.0
PYH2_k127_3901788_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 421.0
PYH2_k127_3901788_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 397.0
PYH2_k127_3901788_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000002387 184.0
PYH2_k127_3901788_4 Glycine-zipper domain - - - 0.000000000000000000000000000003286 124.0
PYH2_k127_3901788_5 Thioredoxin - - - 0.00000000000000000000000000001263 122.0
PYH2_k127_3901788_6 alkyl hydroperoxide reductase - - - 0.0000639 48.0
PYH2_k127_3901788_7 Lactonase, 7-bladed beta-propeller - - - 0.0001043 51.0
PYH2_k127_3901788_8 - - - - 0.0001641 52.0
PYH2_k127_3907268_0 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 587.0
PYH2_k127_3907268_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000006525 74.0
PYH2_k127_3907268_2 Alpha beta hydrolase - - - 0.0000007305 54.0
PYH2_k127_3938376_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 480.0
PYH2_k127_3938376_1 Cysteine-rich domain - - - 0.000000000000000000000000000000002061 132.0
PYH2_k127_3938376_2 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.000000000000000000000000002949 114.0
PYH2_k127_3938376_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000003042 96.0
PYH2_k127_3951918_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 464.0
PYH2_k127_3951918_1 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 310.0
PYH2_k127_3951918_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000114 194.0
PYH2_k127_397175_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 434.0
PYH2_k127_397175_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000341 160.0
PYH2_k127_4011014_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 513.0
PYH2_k127_4011014_1 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 408.0
PYH2_k127_4011014_2 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001721 276.0
PYH2_k127_4011014_3 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009311 250.0
PYH2_k127_4011014_4 Domain of unknown function (DUF4410) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003802 237.0
PYH2_k127_4011014_5 Ion transport 2 domain protein - - - 0.00000000000000000000000000000000002943 143.0
PYH2_k127_4031036_0 - - - - 0.00000000000000002461 81.0
PYH2_k127_4031036_1 Kazal type serine protease inhibitors - - - 0.0000000000000005863 91.0
PYH2_k127_4031036_2 Flavodoxin-like fold - - - 0.000000000000001191 83.0
PYH2_k127_4047614_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.286e-197 622.0
PYH2_k127_4047614_1 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 291.0
PYH2_k127_4047614_2 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000302 243.0
PYH2_k127_4047614_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000007399 189.0
PYH2_k127_4047614_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000000000000000000000001077 176.0
PYH2_k127_4047614_5 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000001817 161.0
PYH2_k127_4047614_6 DRTGG domain - - - 0.00000000000000000000000000000002829 128.0
PYH2_k127_4067136_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.232e-250 787.0
PYH2_k127_4067136_1 COG4448 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 349.0
PYH2_k127_4067136_2 Domain of unknown function DUF128 K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 344.0
PYH2_k127_4067136_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008498 267.0
PYH2_k127_4067136_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000006411 199.0
PYH2_k127_4067136_5 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000002827 164.0
PYH2_k127_4067136_6 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.000000000000000000000000000000000002005 150.0
PYH2_k127_4067136_7 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000005269 81.0
PYH2_k127_4067136_8 gas vesicle protein - - - 0.000000005576 63.0
PYH2_k127_41087_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 344.0
PYH2_k127_41087_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000006578 196.0
PYH2_k127_41087_2 1,4-alpha-glucan branching enzyme activity K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000005176 177.0
PYH2_k127_4152197_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001142 233.0
PYH2_k127_4152197_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000003218 224.0
PYH2_k127_4152197_2 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000002884 191.0
PYH2_k127_4152197_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000008298 113.0
PYH2_k127_4152197_4 Putative regulatory protein - - - 0.000000000000000005895 87.0
PYH2_k127_4159110_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 316.0
PYH2_k127_4159110_1 NADPH-dependent FMN reductase - - - 0.0000000000000007239 86.0
PYH2_k127_4159110_2 FMN binding - - - 0.00000000000002892 82.0
PYH2_k127_4164634_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 499.0
PYH2_k127_4164634_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002095 276.0
PYH2_k127_4164634_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007227 273.0
PYH2_k127_4164634_3 4Fe-4S dicluster domain - - - 0.000000000000000003561 94.0
PYH2_k127_4164634_4 Biotin-protein ligase, N terminal - - - 0.000009283 51.0
PYH2_k127_4171898_0 Pyruvate formate lyase-like K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 580.0
PYH2_k127_4171898_1 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 464.0
PYH2_k127_4171898_2 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 296.0
PYH2_k127_4171898_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004271 265.0
PYH2_k127_4171898_4 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000002479 212.0
PYH2_k127_4171898_5 Uncharacterised ArCR, COG2043 - - - 0.0000000000000003195 88.0
PYH2_k127_4171898_6 Flavodoxin-like fold - - - 0.000000000000003016 79.0
PYH2_k127_4171898_7 dihydromethanopterin reductase activity - - - 0.00000000000003027 75.0
PYH2_k127_4171898_8 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000003583 67.0
PYH2_k127_4174236_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000001396 85.0
PYH2_k127_4174236_1 COG0644 Dehydrogenases (flavoproteins) K00311 - 1.5.5.1 0.00002053 56.0
PYH2_k127_4174236_2 COG0477 Permeases of the major facilitator superfamily - - - 0.00008495 50.0
PYH2_k127_4178120_0 PFAM isocitrate isopropylmalate dehydrogenase K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 553.0
PYH2_k127_4178120_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 446.0
PYH2_k127_4178120_2 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 364.0
PYH2_k127_4178120_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000635 223.0
PYH2_k127_4178120_4 - - - - 0.00000000000000000000000000000000000000000000000002513 183.0
PYH2_k127_4178120_5 the in vivo substrate is - - - 0.00000000000000000000000000000000000000000000000004991 189.0
PYH2_k127_4178120_6 Desulfoferrodoxin K05919 - 1.15.1.2 0.000000000000000000000000000000000000004646 151.0
PYH2_k127_4178120_7 Pkd domain containing protein - - - 0.00000000000001106 87.0
PYH2_k127_4203877_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 475.0
PYH2_k127_4203877_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 332.0
PYH2_k127_4203877_2 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
PYH2_k127_4203877_3 ABC transporter substrate-binding component GldG K01992 - - 0.00000001343 60.0
PYH2_k127_4205611_0 NADH dehydrogenase (quinone) K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 543.0
PYH2_k127_4205611_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000007082 177.0
PYH2_k127_4205611_2 CAAX protease self-immunity - - - 0.000000000000000000000000000000008115 134.0
PYH2_k127_4288756_0 PFAM response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002944 261.0
PYH2_k127_4288756_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000002864 220.0
PYH2_k127_4288756_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001135 212.0
PYH2_k127_4288756_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000003498 207.0
PYH2_k127_4294824_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 486.0
PYH2_k127_4294824_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 415.0
PYH2_k127_4294824_2 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
PYH2_k127_4294824_3 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 325.0
PYH2_k127_4294824_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000001279 186.0
PYH2_k127_4294824_5 4 iron, 4 sulfur cluster binding K00176,K00180,K05524 - 1.2.7.3,1.2.7.8 0.0000000000000134 76.0
PYH2_k127_4294824_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000001412 66.0
PYH2_k127_4311128_0 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 379.0
PYH2_k127_4311128_1 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000009909 220.0
PYH2_k127_4311128_2 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000001914 201.0
PYH2_k127_4311128_3 Protein of unknown function (DUF721) - - - 0.00000000000000001761 85.0
PYH2_k127_4311128_4 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 0.00004337 46.0
PYH2_k127_4335205_0 Domain of unknown function (DUF1846) - - - 2.275e-245 766.0
PYH2_k127_4335205_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 376.0
PYH2_k127_4335205_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001049 278.0
PYH2_k127_4335205_3 COG3264 Small-conductance mechanosensitive channel K22051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002423 286.0
PYH2_k127_434765_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 355.0
PYH2_k127_434765_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 288.0
PYH2_k127_434765_2 TonB dependent receptor K02014 - - 0.00000004526 54.0
PYH2_k127_4362333_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000006028 96.0
PYH2_k127_4362333_1 peptidyl-tyrosine sulfation - - - 0.00000000000006789 83.0
PYH2_k127_4362333_2 YtxH-like protein - - - 0.00000000006922 68.0
PYH2_k127_4362333_3 - - - - 0.0004761 48.0
PYH2_k127_4365367_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 290.0
PYH2_k127_4365367_1 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 291.0
PYH2_k127_4365367_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000001347 53.0
PYH2_k127_4365367_3 Pfam:DUF4102 - - - 0.00001442 49.0
PYH2_k127_4369225_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000002522 202.0
PYH2_k127_4369225_1 Serine aminopeptidase, S33 K06889,K07397 - - 0.000000000000000000000000000000000000003209 156.0
PYH2_k127_4369225_2 Domain of unknown function (DUF4340) - - - 0.000000000000006571 86.0
PYH2_k127_4415896_0 PFAM NADH flavin oxidoreductase NADH oxidase K10797 - 1.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 475.0
PYH2_k127_4415896_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000009505 180.0
PYH2_k127_4415896_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000001649 63.0
PYH2_k127_4415896_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00009764 46.0
PYH2_k127_4455761_0 Glycosyl hydrolases family 28 - - - 0.000000000000000000000001448 122.0
PYH2_k127_4455761_1 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000106 79.0
PYH2_k127_4455761_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000005378 67.0
PYH2_k127_4455761_3 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.0000000004389 74.0
PYH2_k127_4455761_4 regulator of chromosome condensation, RCC1 - - - 0.00000001574 69.0
PYH2_k127_4455761_5 Alpha-L-fucosidase K01206,K07407,K21449 - 3.2.1.22,3.2.1.51 0.00006073 57.0
PYH2_k127_4455761_6 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.0001053 56.0
PYH2_k127_4469659_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 345.0
PYH2_k127_4469659_1 FAD binding domain - - - 0.000000000000000000000000000001699 136.0
PYH2_k127_4469659_2 Uncharacterised ArCR, COG2043 - - - 0.000000000000001923 87.0
PYH2_k127_4469659_3 4Fe-4S binding domain - - - 0.0000000901 63.0
PYH2_k127_4475824_0 basal body rod protein K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 364.0
PYH2_k127_4475824_1 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000001022 175.0
PYH2_k127_4475824_2 Flagellar hook-length control protein K02414 - - 0.000000002447 70.0
PYH2_k127_4501266_0 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 310.0
PYH2_k127_4501266_1 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004563 270.0
PYH2_k127_4501266_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000005319 109.0
PYH2_k127_4501266_3 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000002848 79.0
PYH2_k127_4501266_4 - - - - 0.00000000003265 66.0
PYH2_k127_4521956_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 562.0
PYH2_k127_4521956_1 cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 443.0
PYH2_k127_4521956_2 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000007217 177.0
PYH2_k127_4530350_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.154e-256 801.0
PYH2_k127_4530350_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 533.0
PYH2_k127_4530350_2 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 489.0
PYH2_k127_4530350_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 473.0
PYH2_k127_4530350_4 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000005037 256.0
PYH2_k127_4530350_5 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002547 246.0
PYH2_k127_4530350_6 Protein of unknown function (DUF3047) - - - 0.00000000000000000000004554 109.0
PYH2_k127_4530350_7 - - - - 0.0000000000000000001858 91.0
PYH2_k127_4530350_8 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00001096 50.0
PYH2_k127_4563286_0 Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 5.957e-217 679.0
PYH2_k127_4563286_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 512.0
PYH2_k127_4563286_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 409.0
PYH2_k127_4563286_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 414.0
PYH2_k127_4563286_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 354.0
PYH2_k127_4563286_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000001044 239.0
PYH2_k127_4563286_6 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000008258 184.0
PYH2_k127_4563286_7 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000001024 134.0
PYH2_k127_4582692_0 Domain of unknown function (DUF1846) - - - 7.991e-249 776.0
PYH2_k127_4582692_1 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000006311 265.0
PYH2_k127_4593171_0 Belongs to the ClpX chaperone family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 618.0
PYH2_k127_4593171_1 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 345.0
PYH2_k127_4593171_2 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 334.0
PYH2_k127_4593171_3 Bacterial regulatory protein, Fis family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 344.0
PYH2_k127_4593171_4 Tetratricopeptide repeat - - - 0.000003098 58.0
PYH2_k127_4598155_0 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000002333 154.0
PYH2_k127_4598155_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K00441,K00528,K03522,K03616 - 1.12.98.1,1.18.1.2,1.19.1.1 0.000000000000000000000613 110.0
PYH2_k127_4598155_2 PFAM HhH-GPD superfamily base excision DNA repair protein K03575 - - 0.0000000008558 61.0
PYH2_k127_4600172_0 TIGRFAM adenosine phosphosulphate reductase, alpha subunit K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 563.0
PYH2_k127_4600172_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 - 1.7.7.1,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 431.0
PYH2_k127_4600172_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 403.0
PYH2_k127_4600172_3 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 334.0
PYH2_k127_4600172_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 305.0
PYH2_k127_4600172_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00395 - 1.8.99.2 0.000000000000000000000006598 106.0
PYH2_k127_4600172_6 HMGL-like K02594 - 2.3.3.14 0.000000000000000000505 87.0
PYH2_k127_4600172_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0006978 50.0
PYH2_k127_464029_0 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
PYH2_k127_464029_1 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 348.0
PYH2_k127_464029_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 295.0
PYH2_k127_466162_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000002548 81.0
PYH2_k127_466162_1 NHL repeat - - - 0.0000000004865 73.0
PYH2_k127_466162_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.00001141 57.0
PYH2_k127_46860_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 524.0
PYH2_k127_46860_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 381.0
PYH2_k127_46860_2 ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 313.0
PYH2_k127_46860_3 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005282 271.0
PYH2_k127_46860_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain - - - 0.000003497 51.0
PYH2_k127_4692202_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000001915 206.0
PYH2_k127_4692202_1 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.0000000000000000000000000000000000000003262 167.0
PYH2_k127_4692202_2 peroxiredoxin activity - - - 0.00000000000000000000000000005423 134.0
PYH2_k127_472571_0 nitronate monooxygenase activity K00088,K00459 - 1.1.1.205,1.13.12.16 2.309e-218 681.0
PYH2_k127_472571_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.3e-214 674.0
PYH2_k127_472571_2 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 523.0
PYH2_k127_472571_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 405.0
PYH2_k127_472571_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000001927 155.0
PYH2_k127_4739602_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.344e-199 634.0
PYH2_k127_4739602_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 592.0
PYH2_k127_4739602_10 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000001499 171.0
PYH2_k127_4739602_11 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000005552 151.0
PYH2_k127_4739602_12 response regulator - - - 0.0000000000000000000000000000000000006604 146.0
PYH2_k127_4739602_13 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000002017 96.0
PYH2_k127_4739602_14 Transcriptional regulatory protein, C terminal - - - 0.000000000000000002092 90.0
PYH2_k127_4739602_15 - - - - 0.000000000000005286 79.0
PYH2_k127_4739602_16 Helix-turn-helix domain - - - 0.0000000005847 61.0
PYH2_k127_4739602_17 general secretion pathway protein G K02456 - - 0.000000006353 64.0
PYH2_k127_4739602_18 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K04749 - - 0.0000002636 57.0
PYH2_k127_4739602_19 Pilus assembly protein PilO K02664 - - 0.0000007594 58.0
PYH2_k127_4739602_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 483.0
PYH2_k127_4739602_20 Pilus assembly protein K02662 - - 0.0000007602 61.0
PYH2_k127_4739602_21 NAD(P)-binding Rossmann-like domain - - - 0.000009117 57.0
PYH2_k127_4739602_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
PYH2_k127_4739602_4 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000002658 235.0
PYH2_k127_4739602_5 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000004602 226.0
PYH2_k127_4739602_6 type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000001463 227.0
PYH2_k127_4739602_7 Histidine kinase K07652 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000006269 228.0
PYH2_k127_4739602_8 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000287 219.0
PYH2_k127_4739602_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000004255 207.0
PYH2_k127_4755712_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 325.0
PYH2_k127_4755712_1 - - - - 0.000005798 51.0
PYH2_k127_4789166_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 612.0
PYH2_k127_4789166_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 588.0
PYH2_k127_4789166_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000398 171.0
PYH2_k127_4789166_11 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000000004833 168.0
PYH2_k127_4789166_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000007313 164.0
PYH2_k127_4789166_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000114 142.0
PYH2_k127_4789166_14 SpoVT / AbrB like domain K07172 - - 0.000000000000000000002888 96.0
PYH2_k127_4789166_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0004827 44.0
PYH2_k127_4789166_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 447.0
PYH2_k127_4789166_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 313.0
PYH2_k127_4789166_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 301.0
PYH2_k127_4789166_5 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
PYH2_k127_4789166_6 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000122 246.0
PYH2_k127_4789166_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
PYH2_k127_4789166_8 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000004422 226.0
PYH2_k127_4789166_9 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000917 214.0
PYH2_k127_479048_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 626.0
PYH2_k127_479048_1 AsmA-like C-terminal region - - - 0.00000000000004541 86.0
PYH2_k127_4813929_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 7.94e-200 629.0
PYH2_k127_4813929_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000008541 214.0
PYH2_k127_4813929_2 domain protein - - - 0.000000000000000000000000000000000000004625 148.0
PYH2_k127_4813929_3 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000001717 139.0
PYH2_k127_4813929_4 - - - - 0.00007729 48.0
PYH2_k127_4813929_5 Tetratricopeptide repeat - - - 0.0007277 50.0
PYH2_k127_4822128_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 8.633e-224 701.0
PYH2_k127_4838889_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1263.0
PYH2_k127_4838889_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 378.0
PYH2_k127_4838889_10 Nitrogen regulatory protein P-II K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000002807 51.0
PYH2_k127_4838889_11 Thrombospondin type 3 repeat - - - 0.000003833 59.0
PYH2_k127_4838889_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 361.0
PYH2_k127_4838889_3 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 331.0
PYH2_k127_4838889_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 307.0
PYH2_k127_4838889_5 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000006583 164.0
PYH2_k127_4838889_6 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000007001 145.0
PYH2_k127_4838889_7 NADPH-dependent FMN reductase - - - 0.00000000000000008441 89.0
PYH2_k127_4838889_8 - - - - 0.00000007152 59.0
PYH2_k127_4838889_9 Heavy-metal resistance - - - 0.000001493 56.0
PYH2_k127_4874717_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 495.0
PYH2_k127_4874717_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000006499 148.0
PYH2_k127_4917655_0 3,4-dihydroxy-2-butanone 4-phosphate synthase K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 591.0
PYH2_k127_4917655_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 481.0
PYH2_k127_4917655_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 398.0
PYH2_k127_4917655_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002467 234.0
PYH2_k127_4917655_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000004101 234.0
PYH2_k127_4917655_5 ATP cone domain K07738 - - 0.000000000000000000000000000000000000000000000000000000000128 209.0
PYH2_k127_4917655_6 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000005465 203.0
PYH2_k127_4917655_7 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000163 163.0
PYH2_k127_4917655_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000007168 149.0
PYH2_k127_4917655_9 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000001022 151.0
PYH2_k127_4948672_0 TIGRFAM cysteine K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
PYH2_k127_4948672_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 410.0
PYH2_k127_4948672_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000004041 115.0
PYH2_k127_4948672_11 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000001825 77.0
PYH2_k127_4948672_12 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000002576 62.0
PYH2_k127_4948672_13 radical SAM domain protein - - - 0.0000002886 62.0
PYH2_k127_4948672_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 344.0
PYH2_k127_4948672_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 333.0
PYH2_k127_4948672_4 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000004041 190.0
PYH2_k127_4948672_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000001206 157.0
PYH2_k127_4948672_6 - - - - 0.0000000000000000000000000000000000000179 154.0
PYH2_k127_4948672_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000004279 142.0
PYH2_k127_4948672_8 Belongs to the Fur family K09825,K22297 - - 0.00000000000000000000000000001648 123.0
PYH2_k127_4948672_9 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.000000000000000000000000005935 119.0
PYH2_k127_49939_0 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 456.0
PYH2_k127_49939_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 458.0
PYH2_k127_49939_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001103 293.0
PYH2_k127_49939_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000001669 181.0
PYH2_k127_49939_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.00000000000000000000000000000000000004219 161.0
PYH2_k127_49939_5 Sigma-54 factor interaction domain-containing protein K07713 - - 0.00000000000000000000003979 113.0
PYH2_k127_5033614_0 von Willebrand factor (vWF) type A domain K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 546.0
PYH2_k127_5033614_1 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 390.0
PYH2_k127_5033614_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 388.0
PYH2_k127_5033614_3 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000002008 190.0
PYH2_k127_5033614_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000003516 145.0
PYH2_k127_5033614_5 PFAM CobN magnesium chelatase K02230 - 6.6.1.2 0.00000000000000000000000000001617 121.0
PYH2_k127_5050269_0 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 492.0
PYH2_k127_5050269_1 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 426.0
PYH2_k127_5050269_10 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000004809 141.0
PYH2_k127_5050269_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000008822 132.0
PYH2_k127_5050269_12 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000001595 112.0
PYH2_k127_5050269_13 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000001976 109.0
PYH2_k127_5050269_14 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000009756 115.0
PYH2_k127_5050269_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000004569 73.0
PYH2_k127_5050269_16 PFAM Type IV pilus assembly PilZ - - - 0.0000005005 59.0
PYH2_k127_5050269_17 HEAT repeats - - - 0.00001093 54.0
PYH2_k127_5050269_18 Heavy-metal resistance - - - 0.0004406 49.0
PYH2_k127_5050269_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
PYH2_k127_5050269_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 311.0
PYH2_k127_5050269_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
PYH2_k127_5050269_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000003743 228.0
PYH2_k127_5050269_6 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000001362 190.0
PYH2_k127_5050269_7 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000008094 170.0
PYH2_k127_5050269_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000005807 167.0
PYH2_k127_5050269_9 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000001966 147.0
PYH2_k127_5076187_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 553.0
PYH2_k127_5076187_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 425.0
PYH2_k127_5076187_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 369.0
PYH2_k127_5076187_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001084 278.0
PYH2_k127_5076187_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000105 153.0
PYH2_k127_5076187_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002694 110.0
PYH2_k127_5076187_6 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000002319 109.0
PYH2_k127_5076187_7 Ribosomal L32p protein family K02911 - - 0.000000000000000001491 88.0
PYH2_k127_51365_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.012e-269 837.0
PYH2_k127_51365_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006966 246.0
PYH2_k127_51365_2 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000886 239.0
PYH2_k127_51365_3 Sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000001396 203.0
PYH2_k127_51365_4 Dodecin K09165 - - 0.00000000000000000000000007261 108.0
PYH2_k127_51365_5 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000000000000000006085 99.0
PYH2_k127_515986_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 452.0
PYH2_k127_515986_1 PFAM metal-dependent phosphohydrolase HD sub - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 355.0
PYH2_k127_515986_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 315.0
PYH2_k127_515986_3 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000002161 98.0
PYH2_k127_5189299_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 406.0
PYH2_k127_5189299_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 334.0
PYH2_k127_5189299_10 Aspartyl protease K06985 - - 0.00001194 57.0
PYH2_k127_5189299_11 ABC transporter substrate-binding protein - - - 0.00005279 54.0
PYH2_k127_5189299_2 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
PYH2_k127_5189299_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000007453 195.0
PYH2_k127_5189299_4 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000003112 173.0
PYH2_k127_5189299_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000002299 170.0
PYH2_k127_5189299_6 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000001436 147.0
PYH2_k127_5189299_7 RDD family - - - 0.000000000000000000000000000004346 132.0
PYH2_k127_5189299_8 Cobalamin B12-binding domain protein K16955,K22491 - - 0.000000000000000000004594 106.0
PYH2_k127_5189299_9 PFAM Tetratricopeptide repeat - - - 0.000000005855 65.0
PYH2_k127_520130_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 312.0
PYH2_k127_520130_1 carbamoyl transferase K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002614 298.0
PYH2_k127_520130_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000001108 163.0
PYH2_k127_520130_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00002351 57.0
PYH2_k127_5266569_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1387.0
PYH2_k127_5266569_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 613.0
PYH2_k127_5266569_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 379.0
PYH2_k127_5266569_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 364.0
PYH2_k127_5266569_12 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 317.0
PYH2_k127_5266569_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 325.0
PYH2_k127_5266569_14 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 292.0
PYH2_k127_5266569_15 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000516 267.0
PYH2_k127_5266569_16 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004231 254.0
PYH2_k127_5266569_17 PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000002087 224.0
PYH2_k127_5266569_18 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000007068 222.0
PYH2_k127_5266569_19 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000002512 220.0
PYH2_k127_5266569_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 586.0
PYH2_k127_5266569_20 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000003566 198.0
PYH2_k127_5266569_21 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000106 177.0
PYH2_k127_5266569_22 NUDIX domain - - - 0.00000000000000000000000000000000000000005546 159.0
PYH2_k127_5266569_23 Helix-turn-helix domain - - - 0.000000000000000000001885 104.0
PYH2_k127_5266569_24 acetyltransferase K03789 - 2.3.1.128 0.000308 49.0
PYH2_k127_5266569_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 576.0
PYH2_k127_5266569_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 555.0
PYH2_k127_5266569_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 494.0
PYH2_k127_5266569_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 396.0
PYH2_k127_5266569_7 Thiamine-phosphate synthase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 402.0
PYH2_k127_5266569_8 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 392.0
PYH2_k127_5266569_9 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 389.0
PYH2_k127_5350346_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 520.0
PYH2_k127_5350346_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 372.0
PYH2_k127_5350346_2 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006294 224.0
PYH2_k127_5350346_3 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000007595 183.0
PYH2_k127_5350346_4 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000000001493 104.0
PYH2_k127_5350346_5 TonB-dependent receptor K02014,K16089 - - 0.00006825 53.0
PYH2_k127_5352026_0 Class II vitamin B12-dependent ribonucleotide reductase K00525 - 1.17.4.1 0.0 1478.0
PYH2_k127_5352026_1 PFAM ABC transporter K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 567.0
PYH2_k127_5352026_2 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000002181 95.0
PYH2_k127_5352026_3 Protein of unknown function (DUF475) K09799 - - 0.00000000000000004371 81.0
PYH2_k127_5433164_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003008 265.0
PYH2_k127_5433164_1 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.00000000000000000000000000000000000000000008396 170.0
PYH2_k127_5433164_2 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000006196 166.0
PYH2_k127_5433164_3 - - - - 0.000005548 51.0
PYH2_k127_5447006_0 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000128 111.0
PYH2_k127_5447006_1 Parallel beta-helix repeats - - - 0.000000000000001074 90.0
PYH2_k127_5447006_2 Calcium ion binding. It is involved in the biological process described with cell adhesion K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.000003938 59.0
PYH2_k127_5447006_3 transport system involved in gliding motility, auxiliary component - - - 0.000004452 60.0
PYH2_k127_5447006_4 Endonuclease Exonuclease Phosphatase - - - 0.00002294 58.0
PYH2_k127_5447006_5 ABC-type uncharacterized transport system - - - 0.0001611 55.0
PYH2_k127_5453768_0 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
PYH2_k127_5453768_2 Thrombospondin type 3 repeat - - - 0.0000000000001195 79.0
PYH2_k127_5453768_3 membrane - - - 0.000007753 57.0
PYH2_k127_5465095_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000137 292.0
PYH2_k127_5465095_1 Glycosyltransferase family 87 K13671 - - 0.0000000000539 71.0
PYH2_k127_5482691_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 540.0
PYH2_k127_5482691_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000702 255.0
PYH2_k127_5482691_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000009687 235.0
PYH2_k127_5482691_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002316 180.0
PYH2_k127_5482691_4 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000006733 167.0
PYH2_k127_5482691_5 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000004673 157.0
PYH2_k127_5482691_6 PFAM DRTGG domain - - - 0.000000000000000000000000000000005817 131.0
PYH2_k127_5482691_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000001275 113.0
PYH2_k127_5482691_8 Iron only hydrogenase large subunit, C-terminal domain - - - 0.000000000000000002196 86.0
PYH2_k127_5485212_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.934e-259 814.0
PYH2_k127_5485212_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003758 274.0
PYH2_k127_5485212_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000008712 140.0
PYH2_k127_5485212_3 Sporulation and spore germination - - - 0.0000000000000000000000000009915 120.0
PYH2_k127_5581371_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.283e-298 928.0
PYH2_k127_5581371_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 580.0
PYH2_k127_5581371_2 DNA integration - - - 0.0000000000000000000000000000000000000000000000002803 182.0
PYH2_k127_5586568_0 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 399.0
PYH2_k127_5586568_1 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
PYH2_k127_5586568_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000003325 250.0
PYH2_k127_5586568_3 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000614 213.0
PYH2_k127_5586568_4 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000001486 133.0
PYH2_k127_5586568_5 Belongs to the NifD NifK NifE NifN family K02587 - - 0.00000000000000274 88.0
PYH2_k127_5586568_6 Belongs to the NifD NifK NifE NifN family - - - 0.00000001012 63.0
PYH2_k127_5586568_7 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000001043 57.0
PYH2_k127_5586568_8 Protein of unknown function (DUF1566) - - - 0.0005916 52.0
PYH2_k127_5628344_0 metal ion transport K14445 - - 2.603e-205 654.0
PYH2_k127_5628344_1 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000005686 177.0
PYH2_k127_5630871_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 6.294e-275 858.0
PYH2_k127_5630871_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 7.412e-228 732.0
PYH2_k127_5630871_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000009986 191.0
PYH2_k127_5630871_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000006413 154.0
PYH2_k127_5630871_12 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000004661 132.0
PYH2_k127_5630871_13 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000944 119.0
PYH2_k127_5630871_14 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000002605 120.0
PYH2_k127_5630871_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000546 102.0
PYH2_k127_5630871_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000001022 97.0
PYH2_k127_5630871_17 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000007262 85.0
PYH2_k127_5630871_18 Glycosyl transferase family 21 K03669 - - 0.00000000000000305 77.0
PYH2_k127_5630871_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.2e-205 649.0
PYH2_k127_5630871_3 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 490.0
PYH2_k127_5630871_4 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 465.0
PYH2_k127_5630871_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 451.0
PYH2_k127_5630871_6 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 375.0
PYH2_k127_5630871_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000003158 219.0
PYH2_k127_5630871_8 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
PYH2_k127_5630871_9 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000004759 185.0
PYH2_k127_5651936_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 306.0
PYH2_k127_5651936_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007191 269.0
PYH2_k127_5651936_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000196 225.0
PYH2_k127_5651936_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000001903 163.0
PYH2_k127_5658350_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 506.0
PYH2_k127_5658350_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 332.0
PYH2_k127_5658350_2 COG0811 Biopolymer transport proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
PYH2_k127_5658350_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008094 266.0
PYH2_k127_5658350_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000003729 201.0
PYH2_k127_5658350_5 - - - - 0.000000000000000000000000002115 127.0
PYH2_k127_5658350_6 - - - - 0.00000000001681 75.0
PYH2_k127_5665547_0 Conserved region in glutamate synthase - - - 1.782e-270 838.0
PYH2_k127_5665547_1 Conserved region in glutamate synthase - - - 1.207e-194 619.0
PYH2_k127_5665547_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 470.0
PYH2_k127_5665547_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 339.0
PYH2_k127_5665547_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000006356 161.0
PYH2_k127_5671454_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 4.107e-279 891.0
PYH2_k127_5671454_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.714e-256 804.0
PYH2_k127_5671454_10 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.00000000000000000000000000000000000001255 156.0
PYH2_k127_5671454_11 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.00000000000000000000002968 101.0
PYH2_k127_5671454_12 Protein of unknown function (DUF1329) - - - 0.00000000000000000004716 104.0
PYH2_k127_5671454_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000001369 66.0
PYH2_k127_5671454_14 - - - - 0.00000000001994 77.0
PYH2_k127_5671454_15 Iron only hydrogenase large subunit, C-terminal domain - - - 0.0000000000357 66.0
PYH2_k127_5671454_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.0001912 50.0
PYH2_k127_5671454_2 Exporters of the RND superfamily K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 442.0
PYH2_k127_5671454_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 320.0
PYH2_k127_5671454_4 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000131 212.0
PYH2_k127_5671454_5 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000001175 209.0
PYH2_k127_5671454_6 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000008583 185.0
PYH2_k127_5671454_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000000000000004322 177.0
PYH2_k127_5671454_8 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000108 182.0
PYH2_k127_5671454_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000006865 149.0
PYH2_k127_5695983_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1561.0
PYH2_k127_5695983_1 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 312.0
PYH2_k127_5695983_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000259 67.0
PYH2_k127_5695983_3 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.00000004513 66.0
PYH2_k127_5739285_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 589.0
PYH2_k127_5739285_1 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 492.0
PYH2_k127_5739285_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000006789 96.0
PYH2_k127_5739285_2 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 413.0
PYH2_k127_5739285_3 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 316.0
PYH2_k127_5739285_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000002096 234.0
PYH2_k127_5739285_5 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000003683 228.0
PYH2_k127_5739285_6 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000002818 218.0
PYH2_k127_5739285_7 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000000000000000000000007069 205.0
PYH2_k127_5739285_8 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000003482 199.0
PYH2_k127_5739285_9 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000008925 171.0
PYH2_k127_5741168_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 392.0
PYH2_k127_5741168_1 Chlorophyllase K08099 - 3.1.1.14 0.000000000000000000000000000000000003233 150.0
PYH2_k127_575035_0 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 449.0
PYH2_k127_575035_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 365.0
PYH2_k127_575035_10 SnoaL-like domain - - - 0.0000000000000000000002445 103.0
PYH2_k127_575035_11 phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000004439 66.0
PYH2_k127_575035_12 MaoC like domain - - - 0.0001824 51.0
PYH2_k127_575035_2 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 334.0
PYH2_k127_575035_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 331.0
PYH2_k127_575035_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 313.0
PYH2_k127_575035_5 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 310.0
PYH2_k127_575035_6 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 282.0
PYH2_k127_575035_7 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000004263 233.0
PYH2_k127_575035_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000001475 222.0
PYH2_k127_575035_9 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000000001155 156.0
PYH2_k127_5838929_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1295.0
PYH2_k127_5838929_1 Elongation factor Tu domain 2 K02355 - - 1.513e-244 773.0
PYH2_k127_5838929_10 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 434.0
PYH2_k127_5838929_11 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 420.0
PYH2_k127_5838929_12 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 413.0
PYH2_k127_5838929_13 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 341.0
PYH2_k127_5838929_14 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 284.0
PYH2_k127_5838929_15 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000002812 229.0
PYH2_k127_5838929_16 molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000007456 211.0
PYH2_k127_5838929_17 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000002382 210.0
PYH2_k127_5838929_18 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000008206 214.0
PYH2_k127_5838929_19 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000006429 212.0
PYH2_k127_5838929_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.225e-227 715.0
PYH2_k127_5838929_20 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000001549 208.0
PYH2_k127_5838929_21 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000012 199.0
PYH2_k127_5838929_22 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000002442 200.0
PYH2_k127_5838929_23 PFAM HD domain - - - 0.0000000000000000000000000000000000000000000000000000004911 203.0
PYH2_k127_5838929_24 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000004333 203.0
PYH2_k127_5838929_25 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000001032 176.0
PYH2_k127_5838929_26 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000000000009892 164.0
PYH2_k127_5838929_27 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000007831 160.0
PYH2_k127_5838929_28 methyltransferase - - - 0.000000000000000000000000000000000000002808 153.0
PYH2_k127_5838929_29 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000004749 155.0
PYH2_k127_5838929_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.096e-219 702.0
PYH2_k127_5838929_30 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000402 139.0
PYH2_k127_5838929_31 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000008172 109.0
PYH2_k127_5838929_32 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000005385 104.0
PYH2_k127_5838929_33 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000839 98.0
PYH2_k127_5838929_34 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000003092 89.0
PYH2_k127_5838929_35 Ferritin-like domain K03594 - 1.16.3.1 0.000000000125 68.0
PYH2_k127_5838929_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.022e-213 674.0
PYH2_k127_5838929_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 573.0
PYH2_k127_5838929_6 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 553.0
PYH2_k127_5838929_7 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 531.0
PYH2_k127_5838929_8 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 517.0
PYH2_k127_5838929_9 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 465.0
PYH2_k127_588616_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00184 - - 6.003e-264 846.0
PYH2_k127_588616_1 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 3.367e-220 697.0
PYH2_k127_588616_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 576.0
PYH2_k127_588616_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 300.0
PYH2_k127_588616_4 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008911 267.0
PYH2_k127_588616_5 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000001106 107.0
PYH2_k127_5890377_0 PFAM Glycosyl transferase family 2 K03669 - - 3.161e-230 730.0
PYH2_k127_5890377_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 576.0
PYH2_k127_5890377_2 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000002034 147.0
PYH2_k127_5890377_3 - - - - 0.0002641 51.0
PYH2_k127_5972392_0 Catalyzes the hydrolysis of Xaa-His dipeptides K01270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 401.0
PYH2_k127_5972392_1 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 349.0
PYH2_k127_5988953_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 460.0
PYH2_k127_5988953_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 405.0
PYH2_k127_5988953_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000003258 152.0
PYH2_k127_5988953_3 PFAM Cyclic nucleotide-binding domain - - - 0.000000000000000001176 92.0
PYH2_k127_5988953_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000004471 51.0
PYH2_k127_5988953_5 aspartate kinase activity K00928,K12524 - 1.1.1.3,2.7.2.4 0.000003198 55.0
PYH2_k127_5988953_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0002776 49.0
PYH2_k127_5990868_0 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
PYH2_k127_5990868_1 Ribbon-helix-helix domain - - - 0.00002911 49.0
PYH2_k127_600998_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 413.0
PYH2_k127_600998_1 Nitrite and sulphite reductase 4Fe-4S domain - - - 0.0000000000000000000003082 108.0
PYH2_k127_6047801_0 MacB-like periplasmic core domain K02004 - - 1.414e-259 826.0
PYH2_k127_6047801_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003935 265.0
PYH2_k127_6047801_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
PYH2_k127_6056190_0 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 577.0
PYH2_k127_6056190_1 COG2199 FOG GGDEF domain K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000004071 199.0
PYH2_k127_6066025_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 332.0
PYH2_k127_6066025_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000195 198.0
PYH2_k127_6066025_2 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000001291 141.0
PYH2_k127_6066025_3 YHS domain - - - 0.0000000000000000003228 94.0
PYH2_k127_6066025_4 Large extracellular alpha-helical protein - - - 0.000776 48.0
PYH2_k127_609132_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 601.0
PYH2_k127_609132_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 573.0
PYH2_k127_609132_10 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000001703 69.0
PYH2_k127_609132_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000001405 61.0
PYH2_k127_609132_2 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 494.0
PYH2_k127_609132_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 435.0
PYH2_k127_609132_4 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 427.0
PYH2_k127_609132_5 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 403.0
PYH2_k127_609132_6 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 371.0
PYH2_k127_609132_7 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 337.0
PYH2_k127_609132_8 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
PYH2_k127_609132_9 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000004202 182.0
PYH2_k127_6118876_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1134.0
PYH2_k127_6118876_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.493e-196 628.0
PYH2_k127_6118876_10 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000002607 109.0
PYH2_k127_6118876_11 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000003502 101.0
PYH2_k127_6118876_12 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000001812 86.0
PYH2_k127_6118876_13 4Fe-4S dicluster domain - - - 0.000000008289 62.0
PYH2_k127_6118876_2 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.354e-196 618.0
PYH2_k127_6118876_3 PFAM WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 560.0
PYH2_k127_6118876_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005455 246.0
PYH2_k127_6118876_5 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000003687 215.0
PYH2_k127_6118876_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000001958 201.0
PYH2_k127_6118876_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000005929 179.0
PYH2_k127_6118876_8 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000004248 137.0
PYH2_k127_6118876_9 4 iron, 4 sulfur cluster binding K03522,K13795,K15511,K19516 - 1.14.13.208 0.00000000000000000000000000000136 125.0
PYH2_k127_6120978_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008271 274.0
PYH2_k127_6120978_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000116 245.0
PYH2_k127_6120978_2 Flavodoxin domain K00230 - 1.3.5.3 0.000000000004636 74.0
PYH2_k127_6120978_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00002373 52.0
PYH2_k127_6263207_0 Extracellular solute-binding protein, family 5 - - - 4.658e-255 807.0
PYH2_k127_6263207_1 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 2.861e-213 681.0
PYH2_k127_6263207_10 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000005491 91.0
PYH2_k127_6263207_2 transport systems K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 421.0
PYH2_k127_6263207_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 415.0
PYH2_k127_6263207_4 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 313.0
PYH2_k127_6263207_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 290.0
PYH2_k127_6263207_6 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000001522 179.0
PYH2_k127_6263207_7 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000003186 176.0
PYH2_k127_6263207_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000007438 172.0
PYH2_k127_6263207_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000001162 153.0
PYH2_k127_6283210_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 361.0
PYH2_k127_6283210_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000003336 242.0
PYH2_k127_6283210_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000002372 221.0
PYH2_k127_6286998_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 576.0
PYH2_k127_6286998_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 361.0
PYH2_k127_6286998_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000857 289.0
PYH2_k127_6286998_3 Transport permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000005105 194.0
PYH2_k127_6286998_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000002687 153.0
PYH2_k127_6301238_0 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000003489 192.0
PYH2_k127_6301238_1 Amidohydrolase K07045 - - 0.00000000000000000005902 101.0
PYH2_k127_6301238_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000008507 51.0
PYH2_k127_6334944_0 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 288.0
PYH2_k127_6334944_1 chromate transporter K07240 - - 0.000000000000000000000000000000000000001057 154.0
PYH2_k127_6334944_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K02574 - - 0.000000000001316 79.0
PYH2_k127_635984_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 250.0
PYH2_k127_635984_2 Coproporphyrinogen III oxidase K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.0000007522 57.0
PYH2_k127_635984_3 Uncharacterised MFS-type transporter YbfB K08195 - - 0.0005617 48.0
PYH2_k127_6373056_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 386.0
PYH2_k127_6373056_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000009935 222.0
PYH2_k127_6373056_2 - - - - 0.00000000005024 73.0
PYH2_k127_6451186_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 323.0
PYH2_k127_6451186_1 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 290.0
PYH2_k127_6451186_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000001004 139.0
PYH2_k127_6451186_3 D-alanine [D-alanyl carrier protein] ligase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000009719 87.0
PYH2_k127_6451186_4 D-alanine [D-alanyl carrier protein] ligase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000301 72.0
PYH2_k127_6451186_5 - - - - 0.00002748 55.0
PYH2_k127_6451186_6 Protein of unknown function (DUF1298) - - - 0.00005558 55.0
PYH2_k127_6459757_0 FAD binding domain - - - 0.000000000000000000000000000000000005047 153.0
PYH2_k127_6459757_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000001254 87.0
PYH2_k127_6459757_2 Flavodoxin domain K00230 - 1.3.5.3 0.000000004684 68.0
PYH2_k127_6459757_3 Belongs to the HY2 family K05369 - 1.3.7.2 0.000005826 57.0
PYH2_k127_6521519_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.526e-199 625.0
PYH2_k127_6521519_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 550.0
PYH2_k127_6521519_2 4 iron, 4 sulfur cluster binding K18356 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000002958 207.0
PYH2_k127_6521519_3 NPCBM K07019 - - 0.000000000000000000000001236 121.0
PYH2_k127_6540460_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 518.0
PYH2_k127_6540460_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 410.0
PYH2_k127_6540460_10 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000009129 155.0
PYH2_k127_6540460_11 Hydrolase - GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000001564 130.0
PYH2_k127_6540460_12 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000007909 110.0
PYH2_k127_6540460_13 Domain of unknown function (DUF362) - - - 0.00000000000000000000274 105.0
PYH2_k127_6540460_14 radical SAM domain - - - 0.0000000000000000001969 99.0
PYH2_k127_6540460_15 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000002255 79.0
PYH2_k127_6540460_16 Histidine Phosphotransfer domain - - - 0.000000002832 63.0
PYH2_k127_6540460_17 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin K05370 - 1.3.7.3 0.000002431 57.0
PYH2_k127_6540460_18 Putative zinc-finger - - - 0.0006981 51.0
PYH2_k127_6540460_2 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 312.0
PYH2_k127_6540460_3 Psort location CytoplasmicMembrane, score 10.00 K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002305 284.0
PYH2_k127_6540460_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000002457 187.0
PYH2_k127_6540460_5 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000005438 191.0
PYH2_k127_6540460_6 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000004662 175.0
PYH2_k127_6540460_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001148 172.0
PYH2_k127_6540460_8 NUDIX domain - - - 0.000000000000000000000000000000000000000001623 162.0
PYH2_k127_6540460_9 HDOD domain - - - 0.00000000000000000000000000000000000001178 156.0
PYH2_k127_6559489_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 524.0
PYH2_k127_6559489_1 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 304.0
PYH2_k127_6559489_10 Helix-turn-helix domain - - - 0.000001856 54.0
PYH2_k127_6559489_11 AraC-like ligand binding domain - - - 0.0001007 50.0
PYH2_k127_6559489_2 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 278.0
PYH2_k127_6559489_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000003521 211.0
PYH2_k127_6559489_4 FAD binding domain - - - 0.00000000000000000000000000000000009672 149.0
PYH2_k127_6559489_5 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000004171 93.0
PYH2_k127_6559489_6 Pyridoxamine 5'-phosphate - - - 0.000000000000000001006 93.0
PYH2_k127_6559489_7 Sigma-54 interaction domain K07714 - - 0.0000000002727 63.0
PYH2_k127_6559489_8 Helix-turn-helix domain - - - 0.0000000006833 62.0
PYH2_k127_6559489_9 Cartilage oligomeric matrix protein K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.000000002192 70.0
PYH2_k127_6584503_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 399.0
PYH2_k127_6584503_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 297.0
PYH2_k127_6584503_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 264.0
PYH2_k127_6584503_3 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0060255,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000001286 207.0
PYH2_k127_6584503_4 FAD binding domain - - - 0.0000000004224 61.0
PYH2_k127_6588218_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 1.312e-292 916.0
PYH2_k127_6588218_1 beta-lactamase activity K01058,K07502 - 3.1.1.32,3.1.1.4 0.0000000000000000000001255 103.0
PYH2_k127_6594050_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 341.0
PYH2_k127_6594050_1 FAD binding domain - - - 0.0000000000000000000000000008172 128.0
PYH2_k127_660319_0 PFAM Type II IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 530.0
PYH2_k127_660319_1 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 460.0
PYH2_k127_660319_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 368.0
PYH2_k127_660319_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 354.0
PYH2_k127_660319_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
PYH2_k127_660319_5 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002077 256.0
PYH2_k127_660319_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000008839 212.0
PYH2_k127_660319_7 Flavodoxin-like fold - - - 0.0000000000000000000003776 104.0
PYH2_k127_660319_8 FMN binding - - - 0.00000000000000166 83.0
PYH2_k127_6612906_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
PYH2_k127_6612906_1 dihydromethanopterin reductase activity - - - 0.0000003023 62.0
PYH2_k127_662683_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 482.0
PYH2_k127_662683_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 366.0
PYH2_k127_662683_2 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000000000388 125.0
PYH2_k127_6632582_0 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 365.0
PYH2_k127_6632582_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000001598 175.0
PYH2_k127_6632582_2 PFAM ribonuclease II K01147,K12573 - 3.1.13.1 0.000000001181 61.0
PYH2_k127_6645152_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 413.0
PYH2_k127_6645152_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 399.0
PYH2_k127_6645152_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000278 226.0
PYH2_k127_6645152_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000001578 212.0
PYH2_k127_6645152_4 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000002848 147.0
PYH2_k127_6645152_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000001387 142.0
PYH2_k127_6650730_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 323.0
PYH2_k127_6654075_0 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 372.0
PYH2_k127_6654075_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 307.0
PYH2_k127_6654075_10 - - - - 0.00000001063 66.0
PYH2_k127_6654075_11 PFAM Metal-dependent hydrolase HDOD - - - 0.000002384 55.0
PYH2_k127_6654075_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 299.0
PYH2_k127_6654075_3 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000765 285.0
PYH2_k127_6654075_4 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002217 230.0
PYH2_k127_6654075_5 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000006318 228.0
PYH2_k127_6654075_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000001536 178.0
PYH2_k127_6654075_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000005613 165.0
PYH2_k127_6654075_8 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000421 107.0
PYH2_k127_6654075_9 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000001784 95.0
PYH2_k127_6660187_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1079.0
PYH2_k127_6660187_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 303.0
PYH2_k127_6660187_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
PYH2_k127_6666850_0 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 484.0
PYH2_k127_6666850_1 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 355.0
PYH2_k127_6666850_2 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008016 286.0
PYH2_k127_6666850_3 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000002167 120.0
PYH2_k127_6666850_4 von Willebrand factor (VWF) type A domain - - - 0.000000006571 56.0
PYH2_k127_6667491_0 FAD binding domain - - - 0.0000000000000000000000000000000000000001111 168.0
PYH2_k127_6667491_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 0.00000000000000000000001072 114.0
PYH2_k127_6667491_2 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000008185 87.0
PYH2_k127_6667491_3 FAD binding domain - - - 0.0000000003165 62.0
PYH2_k127_6681051_0 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 488.0
PYH2_k127_6681051_1 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008953 246.0
PYH2_k127_6681051_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000005118 229.0
PYH2_k127_6681051_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000005125 137.0
PYH2_k127_6681051_4 PAC2 family - - - 0.00000000000000000000000000000006967 136.0
PYH2_k127_6683812_0 PFAM Amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 544.0
PYH2_k127_6683812_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000004328 213.0
PYH2_k127_6683812_2 - - - - 0.0000000000000004881 91.0
PYH2_k127_6702161_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 319.0
PYH2_k127_6702161_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000005764 187.0
PYH2_k127_6702161_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000000000000000009188 115.0
PYH2_k127_6702161_3 Aldehyde ferredoxin oxidoreductase, domains 2 3 K03738 - 1.2.7.5 0.00000000000000000000006706 103.0
PYH2_k127_6702161_4 Domain of unknown function (DUF4136) - - - 0.0000000000000000000007732 102.0
PYH2_k127_6715157_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.319e-260 818.0
PYH2_k127_6715157_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.251e-236 758.0
PYH2_k127_6715157_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 473.0
PYH2_k127_6715157_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000008859 262.0
PYH2_k127_6715157_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000001029 229.0
PYH2_k127_6715157_5 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000003597 199.0
PYH2_k127_6715157_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000002859 152.0
PYH2_k127_6715157_7 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001402 128.0
PYH2_k127_6715157_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000009902 120.0
PYH2_k127_6715157_9 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000004721 101.0
PYH2_k127_6716791_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 583.0
PYH2_k127_6716791_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 475.0
PYH2_k127_6716791_2 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 471.0
PYH2_k127_6716791_3 protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000001062 209.0
PYH2_k127_6716791_4 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.0000000000000000000000000000000000000000000003762 169.0
PYH2_k127_6716791_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000000003568 98.0
PYH2_k127_6716791_6 YtxH-like protein - - - 0.0000001206 59.0
PYH2_k127_6737976_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 449.0
PYH2_k127_6737976_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 418.0
PYH2_k127_6737976_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 396.0
PYH2_k127_6737976_3 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 326.0
PYH2_k127_6737976_4 Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000218 295.0
PYH2_k127_6737976_5 PFAM Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004692 254.0
PYH2_k127_6737976_6 COGs COG1150 Heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000004873 119.0
PYH2_k127_6737976_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000003987 88.0
PYH2_k127_6737976_8 phosphorelay signal transduction system - - - 0.00000000000000003823 86.0
PYH2_k127_6737976_9 PFAM PilT protein domain protein - - - 0.0000003625 52.0
PYH2_k127_6742602_0 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000005915 106.0
PYH2_k127_6742602_1 Dimerisation domain - - - 0.00005058 54.0
PYH2_k127_6750093_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 338.0
PYH2_k127_6750093_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002691 205.0
PYH2_k127_6750093_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000002726 216.0
PYH2_k127_6750093_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000003416 144.0
PYH2_k127_6795940_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.655e-235 744.0
PYH2_k127_6795940_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.992e-220 710.0
PYH2_k127_6795940_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000003544 143.0
PYH2_k127_6795940_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.393e-219 690.0
PYH2_k127_6795940_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 496.0
PYH2_k127_6795940_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 422.0
PYH2_k127_6795940_5 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 308.0
PYH2_k127_6795940_6 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
PYH2_k127_6795940_7 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000001372 167.0
PYH2_k127_6795940_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000001806 161.0
PYH2_k127_6795940_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000002047 154.0
PYH2_k127_6839787_0 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 401.0
PYH2_k127_6839787_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001751 270.0
PYH2_k127_6839787_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000008526 173.0
PYH2_k127_6839787_3 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000000000000002929 167.0
PYH2_k127_6839787_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000008263 149.0
PYH2_k127_6842252_0 Major Facilitator Superfamily K08193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 341.0
PYH2_k127_6842252_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000128 146.0
PYH2_k127_6842252_2 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000005578 144.0
PYH2_k127_6844118_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.393e-235 736.0
PYH2_k127_6844118_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 1.596e-211 664.0
PYH2_k127_6844118_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000004829 244.0
PYH2_k127_6844118_3 binding domain protein - - - 0.0000000000000000000000000000001231 134.0
PYH2_k127_6844118_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000008377 125.0
PYH2_k127_6844118_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000002923 90.0
PYH2_k127_6856895_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 552.0
PYH2_k127_6856895_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000003827 152.0
PYH2_k127_6856895_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000007866 78.0
PYH2_k127_6856895_3 TIGRFAM MoaD family protein K03636 - - 0.00000008366 57.0
PYH2_k127_6879227_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.292e-274 852.0
PYH2_k127_6879227_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 436.0
PYH2_k127_6879227_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 392.0
PYH2_k127_6879227_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001382 251.0
PYH2_k127_6879227_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000001355 176.0
PYH2_k127_6879227_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000001581 157.0
PYH2_k127_6901951_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 491.0
PYH2_k127_6901951_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 293.0
PYH2_k127_6901951_2 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 277.0
PYH2_k127_6901951_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000007926 158.0
PYH2_k127_6901951_4 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000007427 81.0
PYH2_k127_6903532_0 Exporters of the RND superfamily K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 416.0
PYH2_k127_6903532_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 393.0
PYH2_k127_6903532_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 390.0
PYH2_k127_6903532_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005243 259.0
PYH2_k127_6903532_4 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.0000000000000000000000000000000000000000000000000000000000000676 218.0
PYH2_k127_6903532_5 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000434 202.0
PYH2_k127_6903532_6 cell wall organization K01448 - 3.5.1.28 0.000000000000001986 89.0
PYH2_k127_6903532_7 cellulose binding - - - 0.000000001387 65.0
PYH2_k127_6903532_8 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0002133 52.0
PYH2_k127_6903532_9 Uncharacterised ArCR, COG2043 - - - 0.0003777 51.0
PYH2_k127_6951760_0 Mur ligase middle domain K01932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 384.0
PYH2_k127_6951760_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 341.0
PYH2_k127_6951760_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001036 237.0
PYH2_k127_6951760_4 Capsule biosynthesis CapC K22116 - - 0.000000000000000000000000000001327 126.0
PYH2_k127_6954146_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1322.0
PYH2_k127_6954146_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 2.018e-280 884.0
PYH2_k127_6954146_2 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 368.0
PYH2_k127_6954146_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 359.0
PYH2_k127_6954146_4 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000001542 139.0
PYH2_k127_6954146_5 Multicopper oxidase - - - 0.00000000000000002467 85.0
PYH2_k127_6954146_6 mercury ion transmembrane transporter activity K07213 - - 0.000000000001191 70.0
PYH2_k127_6954146_7 Copper resistance protein CopZ K07213 - - 0.00000001795 57.0
PYH2_k127_6955197_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 346.0
PYH2_k127_6955197_1 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
PYH2_k127_6955197_2 Aminotransferase class-III K21778 - - 0.00000000000000000000000000000000000000000000000000000000004057 220.0
PYH2_k127_6955197_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000001429 152.0
PYH2_k127_6955197_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000007324 148.0
PYH2_k127_6955197_5 Phosphopantetheine attachment site - - - 0.00000000000000000000000003885 112.0
PYH2_k127_6955197_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000001015 111.0
PYH2_k127_6955197_7 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000007139 106.0
PYH2_k127_6967054_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.299e-280 878.0
PYH2_k127_6967054_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.639e-230 726.0
PYH2_k127_6967054_10 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000929 168.0
PYH2_k127_6967054_11 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000005909 136.0
PYH2_k127_6967054_12 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000006833 120.0
PYH2_k127_6967054_13 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000009902 120.0
PYH2_k127_6967054_14 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000408 113.0
PYH2_k127_6967054_15 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000001193 96.0
PYH2_k127_6967054_16 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00000000000001044 81.0
PYH2_k127_6967054_17 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000001163 68.0
PYH2_k127_6967054_18 Cysteine-rich domain - - - 0.000000007942 59.0
PYH2_k127_6967054_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
PYH2_k127_6967054_3 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 413.0
PYH2_k127_6967054_4 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 364.0
PYH2_k127_6967054_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 319.0
PYH2_k127_6967054_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 309.0
PYH2_k127_6967054_7 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000007386 232.0
PYH2_k127_6967054_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000567 215.0
PYH2_k127_6967054_9 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000002126 173.0
PYH2_k127_6983952_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 514.0
PYH2_k127_6983952_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 415.0
PYH2_k127_6983952_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000005224 241.0
PYH2_k127_6983952_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001616 213.0
PYH2_k127_6983952_4 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000126 157.0
PYH2_k127_6983952_5 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.000000000000001017 84.0
PYH2_k127_6983952_6 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000005705 70.0
PYH2_k127_6983952_7 Protein of unknown function (DUF1460) - - - 0.00001345 52.0
PYH2_k127_7051349_0 belongs to the CobB CobQ family K00625,K13788 - 2.3.1.8 1.195e-215 681.0
PYH2_k127_7051349_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 526.0
PYH2_k127_7051349_2 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 475.0
PYH2_k127_7106760_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 340.0
PYH2_k127_7106760_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005293 268.0
PYH2_k127_7106760_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006569 266.0
PYH2_k127_7106760_3 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000003717 166.0
PYH2_k127_7106760_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000006741 166.0
PYH2_k127_7106760_5 - - - - 0.000000000000007829 88.0
PYH2_k127_7106760_6 FlgD Ig-like domain K15924 - 3.2.1.136 0.00001467 57.0
PYH2_k127_7135058_0 PAS domain K13598 - 2.7.13.3 8.029e-244 774.0
PYH2_k127_7135058_1 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 520.0
PYH2_k127_7135058_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 384.0
PYH2_k127_7135058_3 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 294.0
PYH2_k127_7135058_4 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000001575 117.0
PYH2_k127_7154123_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 344.0
PYH2_k127_7154123_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000002114 177.0
PYH2_k127_7154123_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000003514 135.0
PYH2_k127_7154123_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000005384 49.0
PYH2_k127_7156736_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 441.0
PYH2_k127_7156736_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000001814 191.0
PYH2_k127_7156736_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000001943 178.0
PYH2_k127_7156736_3 - - - - 0.0009196 50.0
PYH2_k127_7173959_0 Arylesterase - - - 0.00000000000000000000000000000000000000000003436 175.0
PYH2_k127_7173959_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000004234 121.0
PYH2_k127_7173959_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000357 66.0
PYH2_k127_7173959_3 Red chlorophyll catabolite reductase (RCC reductase) - - - 0.0002925 52.0
PYH2_k127_7185394_0 acetyl-CoA hydrolase transferase - - - 1.578e-207 662.0
PYH2_k127_7185394_1 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 462.0
PYH2_k127_7185394_2 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000004278 272.0
PYH2_k127_7185394_3 PFAM MltA K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002864 253.0
PYH2_k127_7185394_4 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000009307 237.0
PYH2_k127_7185394_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000132 194.0
PYH2_k127_7185394_6 serine-type D-Ala-D-Ala carboxypeptidase activity K07259 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006807,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009987,GO:0016043,GO:0016787,GO:0016998,GO:0017171,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0032505,GO:0033218,GO:0033293,GO:0036094,GO:0042597,GO:0043093,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044464,GO:0045229,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:0140096,GO:1901135,GO:1901136,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000009561 153.0
PYH2_k127_7185394_7 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000003932 108.0
PYH2_k127_7185394_8 NmrA-like family - - - 0.0000000000000000000001585 109.0
PYH2_k127_725197_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 432.0
PYH2_k127_725197_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
PYH2_k127_725197_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000007552 177.0
PYH2_k127_725197_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K00441,K00528,K03522,K03616 - 1.12.98.1,1.18.1.2,1.19.1.1 0.0000000000004653 76.0
PYH2_k127_7287712_0 Transglutaminase-like superfamily - - - 0.00000000175 70.0
PYH2_k127_7287712_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000005351 61.0
PYH2_k127_7307894_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008189 278.0
PYH2_k127_7307894_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002615 267.0
PYH2_k127_7307894_2 Diguanylate cyclase K21084 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000001387 248.0
PYH2_k127_7307894_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
PYH2_k127_7307894_4 PFAM ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000007217 188.0
PYH2_k127_7313771_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0 1247.0
PYH2_k127_7313771_1 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 2.564e-271 854.0
PYH2_k127_7313771_2 WYL domain K13573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001272 273.0
PYH2_k127_7313771_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000001549 199.0
PYH2_k127_7338251_0 Bacterial regulatory protein, Fis family K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 605.0
PYH2_k127_7338251_1 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 474.0
PYH2_k127_7338251_10 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 - 2.1.1.44 0.00009838 53.0
PYH2_k127_7338251_2 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
PYH2_k127_7338251_3 PFAM O-methyltransferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 376.0
PYH2_k127_7338251_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 355.0
PYH2_k127_7338251_5 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000002064 266.0
PYH2_k127_7338251_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000006228 211.0
PYH2_k127_7338251_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000003511 184.0
PYH2_k127_7338251_8 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000009223 134.0
PYH2_k127_7363802_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 462.0
PYH2_k127_7363802_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000007961 134.0
PYH2_k127_7363802_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000007002 78.0
PYH2_k127_7363802_3 PFAM Tetratricopeptide - - - 0.0007214 53.0
PYH2_k127_7381465_0 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 6.44e-211 662.0
PYH2_k127_7381465_1 N-4 methylation of cytosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 315.0
PYH2_k127_7381465_2 Argininosuccinate lyase K01755 GO:0000050,GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001363 273.0
PYH2_k127_7381465_3 - - - - 0.0000000000000000003915 96.0
PYH2_k127_7381465_4 Belongs to the peptidase S8 family K01342,K14645 - 3.4.21.62 0.0008582 48.0
PYH2_k127_7410331_0 GTP-binding protein TypA K06207 - - 1.006e-231 732.0
PYH2_k127_7410331_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 522.0
PYH2_k127_7410331_2 CoA carboxylase activity K01615,K01965,K02160 - 4.1.1.70,6.4.1.3 0.0000000000000000006343 87.0
PYH2_k127_7410331_3 Acyl-CoA hydrolase - - - 0.000000000000000005823 88.0
PYH2_k127_7410331_4 PFAM Transglycosylase SLT domain K08307 - - 0.0000002158 60.0
PYH2_k127_7421641_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 507.0
PYH2_k127_7421641_1 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 351.0
PYH2_k127_7421641_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 309.0
PYH2_k127_7421641_3 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000003111 222.0
PYH2_k127_7421641_4 Transposase - - - 0.0000000000000000000000000000000000000000000000000000006428 200.0
PYH2_k127_7421641_5 Carboxypeptidase regulatory-like domain K01365,K02030,K14475 - 3.4.22.15 0.00000000000000000002829 102.0
PYH2_k127_7473852_0 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 319.0
PYH2_k127_7473852_1 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002464 288.0
PYH2_k127_7473852_2 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005054 269.0
PYH2_k127_7473852_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000004432 221.0
PYH2_k127_7473852_4 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000002872 217.0
PYH2_k127_750651_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.579e-254 800.0
PYH2_k127_750651_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007172 260.0
PYH2_k127_750651_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
PYH2_k127_750651_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000004775 209.0
PYH2_k127_750651_4 PFAM Phosphate-starvation-inducible - - - 0.000000000000000000000000000000000000000000000000000155 190.0
PYH2_k127_750651_5 chorismate binding enzyme K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000006431 166.0
PYH2_k127_750651_6 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000002297 154.0
PYH2_k127_7508327_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 338.0
PYH2_k127_7508327_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002273 257.0
PYH2_k127_7508327_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000001397 175.0
PYH2_k127_7508327_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000007738 57.0
PYH2_k127_7513121_0 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 521.0
PYH2_k127_7513121_1 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 455.0
PYH2_k127_7513121_2 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000376 96.0
PYH2_k127_751489_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 470.0
PYH2_k127_751489_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000002188 203.0
PYH2_k127_751489_2 4Fe-4S dicluster domain - - - 0.0001904 53.0
PYH2_k127_751489_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.000307 45.0
PYH2_k127_7516350_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1095.0
PYH2_k127_7516350_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 9.219e-224 714.0
PYH2_k127_7516350_10 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 408.0
PYH2_k127_7516350_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 369.0
PYH2_k127_7516350_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 363.0
PYH2_k127_7516350_13 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 346.0
PYH2_k127_7516350_14 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 336.0
PYH2_k127_7516350_15 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 319.0
PYH2_k127_7516350_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 308.0
PYH2_k127_7516350_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 306.0
PYH2_k127_7516350_18 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000307 269.0
PYH2_k127_7516350_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000004583 260.0
PYH2_k127_7516350_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.167e-215 688.0
PYH2_k127_7516350_20 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000001829 239.0
PYH2_k127_7516350_21 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000004082 239.0
PYH2_k127_7516350_22 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000001379 198.0
PYH2_k127_7516350_23 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000001255 133.0
PYH2_k127_7516350_24 3D domain protein K21471 - - 0.000000000000000000000000881 111.0
PYH2_k127_7516350_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.258e-213 693.0
PYH2_k127_7516350_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.518e-196 619.0
PYH2_k127_7516350_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 618.0
PYH2_k127_7516350_6 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 596.0
PYH2_k127_7516350_7 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 580.0
PYH2_k127_7516350_8 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 473.0
PYH2_k127_7516350_9 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 467.0
PYH2_k127_7518088_0 ABC transporter K03701 - - 0.0 1180.0
PYH2_k127_7534703_0 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 1.265e-223 724.0
PYH2_k127_7534703_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000004855 228.0
PYH2_k127_7534703_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000005066 185.0
PYH2_k127_753472_0 TIGRFAM flagellar motor stator protein MotA K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 286.0
PYH2_k127_753472_1 OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000002118 233.0
PYH2_k127_753472_2 ATP-binding region ATPase domain protein, histidine kinase dimerization and phosphoacceptor region - - - 0.00000000000000002244 85.0
PYH2_k127_753472_3 PFAM Type IV pilus assembly PilZ - - - 0.00002044 53.0
PYH2_k127_7603061_0 Exporters of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 373.0
PYH2_k127_7603061_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 369.0
PYH2_k127_7603061_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000005001 209.0
PYH2_k127_7603061_3 Uridine phosphorylase K00757 - 2.4.2.3 0.00000000000000000000000000000000007478 143.0
PYH2_k127_7603061_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000001806 127.0
PYH2_k127_7603061_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000004646 68.0
PYH2_k127_7603061_6 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000007621 71.0
PYH2_k127_7625832_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000002203 173.0
PYH2_k127_7625832_2 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000009334 145.0
PYH2_k127_767864_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.392e-240 760.0
PYH2_k127_767864_1 FlhB HrpN YscU SpaS Family K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 369.0
PYH2_k127_767864_2 Flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 306.0
PYH2_k127_767864_3 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 294.0
PYH2_k127_767864_4 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000000000000000000000000000000000000001248 203.0
PYH2_k127_767864_5 Flagellar motor switch protein FliN K02417 - - 0.00000000000000000000000000000000003095 141.0
PYH2_k127_767864_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000288 137.0
PYH2_k127_767864_7 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000003217 132.0
PYH2_k127_767864_8 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000000000001253 108.0
PYH2_k127_767864_9 Flagellar biosynthesis protein, FliO - - - 0.00000001777 62.0
PYH2_k127_7731397_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 479.0
PYH2_k127_7731397_1 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 428.0
PYH2_k127_7731397_10 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 308.0
PYH2_k127_7731397_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 302.0
PYH2_k127_7731397_12 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 308.0
PYH2_k127_7731397_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 256.0
PYH2_k127_7731397_14 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000002298 175.0
PYH2_k127_7731397_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000009835 176.0
PYH2_k127_7731397_16 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000006604 137.0
PYH2_k127_7731397_17 Haemolytic - - - 0.000000000000000000002493 99.0
PYH2_k127_7731397_18 Flavodoxin-like fold - - - 0.0000000000000002035 91.0
PYH2_k127_7731397_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 406.0
PYH2_k127_7731397_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 407.0
PYH2_k127_7731397_4 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 403.0
PYH2_k127_7731397_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 396.0
PYH2_k127_7731397_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 379.0
PYH2_k127_7731397_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 362.0
PYH2_k127_7731397_8 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 316.0
PYH2_k127_7731397_9 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 318.0
PYH2_k127_7733673_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 4.729e-275 864.0
PYH2_k127_7733673_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 591.0
PYH2_k127_7733673_10 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 320.0
PYH2_k127_7733673_11 COG1045 Serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 300.0
PYH2_k127_7733673_12 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001644 276.0
PYH2_k127_7733673_13 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002968 272.0
PYH2_k127_7733673_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004745 264.0
PYH2_k127_7733673_15 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001966 241.0
PYH2_k127_7733673_16 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000001623 194.0
PYH2_k127_7733673_17 lipid binding K03098 - - 0.000000000000000000000000000000000000000000001211 174.0
PYH2_k127_7733673_18 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000195 153.0
PYH2_k127_7733673_19 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.0000000000000000000000000000000000003447 150.0
PYH2_k127_7733673_2 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 588.0
PYH2_k127_7733673_20 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000003739 149.0
PYH2_k127_7733673_21 PFAM pyruvate phosphate dikinase PEP pyruvate-binding K01007 - 2.7.9.2 0.000000000000000000000000000000000004582 149.0
PYH2_k127_7733673_22 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000001436 138.0
PYH2_k127_7733673_23 belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000005417 138.0
PYH2_k127_7733673_24 - - - - 0.000000000000000000000000000021 123.0
PYH2_k127_7733673_25 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000006592 119.0
PYH2_k127_7733673_26 lycopene cyclase - - - 0.0000000000000000000009449 98.0
PYH2_k127_7733673_27 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000000776 96.0
PYH2_k127_7733673_28 lycopene cyclase - - - 0.00000000000000000009354 94.0
PYH2_k127_7733673_29 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000121 93.0
PYH2_k127_7733673_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 556.0
PYH2_k127_7733673_30 Rubrerythrin - - - 0.000000000000000009543 84.0
PYH2_k127_7733673_31 metallopeptidase activity K03592 - - 0.000000000000005914 78.0
PYH2_k127_7733673_32 PFAM Rubrerythrin - GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0006091,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009266,GO:0009268,GO:0009408,GO:0009409,GO:0009628,GO:0009636,GO:0009651,GO:0009987,GO:0010035,GO:0010446,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0016999,GO:0017001,GO:0017144,GO:0022900,GO:0033554,GO:0034599,GO:0034605,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070417,GO:0070482,GO:0070887,GO:0071214,GO:0071236,GO:0071453,GO:0071467,GO:0071469,GO:0071470,GO:0071472,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:0104004,GO:1901700,GO:1901701,GO:1990748 - 0.0000000000001187 70.0
PYH2_k127_7733673_33 Glutaredoxin - - - 0.0000000000005584 70.0
PYH2_k127_7733673_34 Rubrerythrin - - - 0.00000000011 68.0
PYH2_k127_7733673_35 Ferritin-like domain - - - 0.0000000005322 67.0
PYH2_k127_7733673_36 pyridoxamine 5'-phosphate K07005 - - 0.000000002482 67.0
PYH2_k127_7733673_38 - - - - 0.000001504 53.0
PYH2_k127_7733673_39 Cytochrome c - - - 0.0000168 52.0
PYH2_k127_7733673_4 PFAM Flavodoxin K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 483.0
PYH2_k127_7733673_40 lysine biosynthesis protein LysW K05826 - - 0.00009243 46.0
PYH2_k127_7733673_41 TRL-like protein family - - - 0.000404 47.0
PYH2_k127_7733673_5 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 458.0
PYH2_k127_7733673_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 456.0
PYH2_k127_7733673_7 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 429.0
PYH2_k127_7733673_8 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 369.0
PYH2_k127_7733673_9 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 346.0
PYH2_k127_7793652_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 2.568e-295 924.0
PYH2_k127_7793652_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000004802 195.0
PYH2_k127_7838589_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 587.0
PYH2_k127_7838589_1 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 499.0
PYH2_k127_7838589_2 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 492.0
PYH2_k127_7838589_3 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 469.0
PYH2_k127_7838589_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 304.0
PYH2_k127_7838589_5 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000007938 239.0
PYH2_k127_7838589_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000003957 233.0
PYH2_k127_7838589_7 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000000000008987 143.0
PYH2_k127_7838589_8 conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000001888 50.0
PYH2_k127_7838589_9 Belongs to the 'phage' integrase family K14059 - - 0.0006651 43.0
PYH2_k127_7843523_0 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000008109 170.0
PYH2_k127_7843523_1 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000001423 148.0
PYH2_k127_7843523_2 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000001185 104.0
PYH2_k127_7843523_3 - - - - 0.00000000000000000000006746 111.0
PYH2_k127_7852841_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000001156 233.0
PYH2_k127_7852841_1 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002421 225.0
PYH2_k127_7878192_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1668.0
PYH2_k127_7878192_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.508e-278 865.0
PYH2_k127_7878192_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.338e-196 622.0
PYH2_k127_7878192_3 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 418.0
PYH2_k127_7878192_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003475 263.0
PYH2_k127_7878192_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000105 231.0
PYH2_k127_7878192_6 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000004331 240.0
PYH2_k127_7878192_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000146 184.0
PYH2_k127_7878192_8 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000001001 105.0
PYH2_k127_7878192_9 Phage integrase family - - - 0.0000000001533 62.0
PYH2_k127_7887327_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003939 259.0
PYH2_k127_7887327_1 FAD binding domain K05797 - 1.17.99.1 0.0000000000000000000000000000000000000000000000538 187.0
PYH2_k127_7887327_2 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.00000000000000000007791 104.0
PYH2_k127_7919253_0 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000483 289.0
PYH2_k127_7919253_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000004015 195.0
PYH2_k127_7919253_2 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000227 180.0
PYH2_k127_7919253_3 O-acyltransferase activity K00661,K21379 - 2.3.1.209,2.3.1.79 0.0000000000000000000007263 103.0
PYH2_k127_7919253_4 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000003215 76.0
PYH2_k127_7919253_5 PFAM Methyltransferase type 11 - - - 0.00000000003419 72.0
PYH2_k127_7959220_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 520.0
PYH2_k127_7959220_1 Psort location Cytoplasmic, score K06934 - - 0.0000000000000000000000000000000000000000000006791 169.0
PYH2_k127_7959220_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000006068 104.0
PYH2_k127_7959220_3 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000001391 95.0
PYH2_k127_7959220_4 von Willebrand factor type A - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001492 58.0
PYH2_k127_7959220_5 DSBA oxidoreductase - - - 0.000001971 57.0
PYH2_k127_7970863_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 488.0
PYH2_k127_7970863_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008726 253.0
PYH2_k127_7970863_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000009554 142.0
PYH2_k127_7970863_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000003202 88.0
PYH2_k127_7973063_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.273e-224 698.0
PYH2_k127_7973063_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 2.38e-203 643.0
PYH2_k127_7973063_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000002873 178.0
PYH2_k127_7973063_11 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000003414 179.0
PYH2_k127_7973063_12 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000007585 158.0
PYH2_k127_7973063_13 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 0.00000000000000000000000000000000000000003731 154.0
PYH2_k127_7973063_14 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000009521 151.0
PYH2_k127_7973063_15 Binds the 23S rRNA K02909 - - 0.00000000000000000000000003757 109.0
PYH2_k127_7973063_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 456.0
PYH2_k127_7973063_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 457.0
PYH2_k127_7973063_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 347.0
PYH2_k127_7973063_5 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 314.0
PYH2_k127_7973063_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 304.0
PYH2_k127_7973063_7 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003524 254.0
PYH2_k127_7973063_8 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000002214 199.0
PYH2_k127_7973063_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000001159 191.0
PYH2_k127_7974131_0 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000189 237.0
PYH2_k127_7974131_1 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000003001 196.0
PYH2_k127_7974131_2 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000000000000008517 87.0
PYH2_k127_7974131_3 pilus assembly protein PilW K02459 - - 0.000000000000001174 88.0
PYH2_k127_7974131_4 General secretion pathway protein K02461 - - 0.0000000003516 73.0
PYH2_k127_7974131_5 fimbrial assembly K02461 - - 0.00000000187 70.0
PYH2_k127_7995181_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 359.0
PYH2_k127_7995181_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 357.0
PYH2_k127_7995181_2 radical SAM domain protein K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 342.0
PYH2_k127_7995181_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 337.0
PYH2_k127_7995181_4 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 302.0
PYH2_k127_7995181_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002441 273.0
PYH2_k127_7995181_6 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000003045 253.0
PYH2_k127_7995181_7 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000001123 145.0
PYH2_k127_7995181_8 DDE superfamily endonuclease K07494 - - 0.00000000004777 63.0
PYH2_k127_8010894_0 aminotransferase, class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 486.0
PYH2_k127_8010894_1 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 431.0
PYH2_k127_8010894_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
PYH2_k127_8028890_0 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003028 256.0
PYH2_k127_8028890_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000008373 181.0
PYH2_k127_8028890_2 formate dehydrogenase - - - 0.000000000000000000000000000000000000000001468 180.0
PYH2_k127_8035375_0 PFAM asparagine synthase K01953 - 6.3.5.4 1.135e-199 641.0
PYH2_k127_8035375_1 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 398.0
PYH2_k127_8035375_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 396.0
PYH2_k127_8035375_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 347.0
PYH2_k127_8035375_4 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000006847 186.0
PYH2_k127_8035375_5 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000001678 192.0
PYH2_k127_8035375_6 lysyltransferase activity K07027,K20468 - - 0.00000000000000000000000000000000005483 145.0
PYH2_k127_8035375_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000001673 138.0
PYH2_k127_8035375_8 methyltransferase K07755 - 2.1.1.137 0.00001657 55.0
PYH2_k127_8131518_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 587.0
PYH2_k127_8131518_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182,K16874 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000001224 212.0
PYH2_k127_8131518_2 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000002123 146.0
PYH2_k127_8131518_3 FAD binding domain - - - 0.00000000000000000000000000000000000035 156.0
PYH2_k127_8131518_4 FAD binding domain - - - 0.00000000000000000000000000003521 132.0
PYH2_k127_8131518_5 QacR-like protein, C-terminal region - - - 0.00000000000000000003279 100.0
PYH2_k127_8131518_6 FAD binding domain - - - 0.0000000003052 68.0
PYH2_k127_8131518_7 KR domain K00059 - 1.1.1.100 0.0000000003595 63.0
PYH2_k127_8131518_8 4Fe-4S binding domain protein - - - 0.000000003995 61.0
PYH2_k127_8133346_0 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 496.0
PYH2_k127_8133346_1 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 484.0
PYH2_k127_8133346_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 372.0
PYH2_k127_8133346_3 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 338.0
PYH2_k127_8133346_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 271.0
PYH2_k127_8133346_5 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000001222 188.0
PYH2_k127_8152291_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 430.0
PYH2_k127_8152291_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005277 272.0
PYH2_k127_8152291_2 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000000000818 178.0
PYH2_k127_8152291_3 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000002122 66.0
PYH2_k127_8152889_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01069,K03797 - 3.1.2.6,3.4.21.102 3.846e-209 660.0
PYH2_k127_8152889_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 478.0
PYH2_k127_8152889_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 385.0
PYH2_k127_8152889_3 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 340.0
PYH2_k127_8152889_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000003013 204.0
PYH2_k127_8152889_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000003933 164.0
PYH2_k127_8152889_6 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000009551 126.0
PYH2_k127_8164805_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002343 248.0
PYH2_k127_8164805_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000001181 229.0
PYH2_k127_8164805_2 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
PYH2_k127_8164805_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000003639 214.0
PYH2_k127_8164805_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000007949 206.0
PYH2_k127_8205737_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 449.0
PYH2_k127_8205737_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 286.0
PYH2_k127_8205737_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004393 198.0
PYH2_k127_8205737_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002494 175.0
PYH2_k127_8205737_4 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001048 160.0
PYH2_k127_8205737_5 Ribosomal protein L36 K02919 - - 0.0000000000007961 68.0
PYH2_k127_8213253_0 TIGRFAM precorrin-3B C17-methyltransferase K05934,K21479 - 2.1.1.131,2.1.1.272 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
PYH2_k127_8213253_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000002966 72.0
PYH2_k127_8213253_2 DDE domain K07497 - - 0.00006046 46.0
PYH2_k127_8228222_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 404.0
PYH2_k127_8228222_1 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 317.0
PYH2_k127_8228222_10 PFAM Anti-sigma-28 factor FlgM K02398 - - 0.000002799 53.0
PYH2_k127_8228222_2 Rod binding protein K21471 - - 0.000000000000000000000000000000000000000002414 166.0
PYH2_k127_8228222_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000001132 162.0
PYH2_k127_8228222_4 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000000000000006673 139.0
PYH2_k127_8228222_5 flagella basal body P-ring formation protein FlgA K02386 - - 0.000000000000000000000000000000004112 132.0
PYH2_k127_8228222_6 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000000000006053 138.0
PYH2_k127_8228222_7 Domain of unknown function (DUF1805) - - - 0.00000000000000000000000000005096 119.0
PYH2_k127_8228222_8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000003117 81.0
PYH2_k127_8231973_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 313.0
PYH2_k127_8231973_1 peptidase U32 - - - 0.000000000000000000000000000000000001189 150.0
PYH2_k127_8231973_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000005517 88.0
PYH2_k127_8231973_3 PFAM Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000002827 53.0
PYH2_k127_8231973_4 Ethanolamine utilisation EutQ family protein K04030 - - 0.0001157 50.0
PYH2_k127_8273047_0 Belongs to the selenophosphate synthase 1 family. Class I subfamily K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 441.0
PYH2_k127_8273047_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
PYH2_k127_8273047_2 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000002606 226.0
PYH2_k127_8273047_3 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000002877 197.0
PYH2_k127_8273047_4 TIGRFAM chlorophyllide reductase subunit Z K11335 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000007724 133.0
PYH2_k127_8273047_5 PFAM Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 0.000000000004558 78.0
PYH2_k127_8290947_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.665e-223 726.0
PYH2_k127_8290947_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 516.0
PYH2_k127_8290947_2 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 379.0
PYH2_k127_8290947_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001645 256.0
PYH2_k127_8290947_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000506 180.0
PYH2_k127_8294199_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 419.0
PYH2_k127_8294199_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 294.0
PYH2_k127_8294199_2 - - - - 0.0000000000001247 76.0
PYH2_k127_8294199_3 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000007538 73.0
PYH2_k127_8315295_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 558.0
PYH2_k127_8315295_1 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 516.0
PYH2_k127_8315295_2 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009267 270.0
PYH2_k127_8340752_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000363 197.0
PYH2_k127_8340752_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000002167 177.0
PYH2_k127_8340752_3 metallopeptidase activity - - - 0.000000000000000000000000001206 129.0
PYH2_k127_8340752_4 Cold shock K03704 - - 0.00000000000000000000000002671 109.0
PYH2_k127_8340752_5 Cellulose Binding Domain Type IV - - - 0.0000004239 62.0
PYH2_k127_8356494_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 505.0
PYH2_k127_8356494_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000001549 166.0
PYH2_k127_8356494_2 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000004053 118.0
PYH2_k127_8357952_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.27e-322 1022.0
PYH2_k127_8357952_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 623.0
PYH2_k127_8357952_2 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000006522 173.0
PYH2_k127_8357952_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000001617 150.0
PYH2_k127_8357952_4 Thrombospondin type 3 repeat - - - 0.00001183 58.0
PYH2_k127_8357952_5 Protein of unknown function (DUF2442) - - - 0.00006635 55.0
PYH2_k127_8357952_6 Cadherin domain - - - 0.0002526 53.0
PYH2_k127_8365946_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 555.0
PYH2_k127_8365946_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000000007218 203.0
PYH2_k127_8365946_2 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.0004154 50.0
PYH2_k127_8384481_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.011e-309 964.0
PYH2_k127_8384481_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 426.0
PYH2_k127_8384481_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 312.0
PYH2_k127_8384481_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006534 275.0
PYH2_k127_8384481_4 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000006614 233.0
PYH2_k127_8438922_0 Protein of unknown function (DUF1698) - - - 0.000000000000000000000001593 109.0
PYH2_k127_8438922_1 arylsulfatase A - - - 0.000000000000000001133 101.0
PYH2_k127_8449427_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.699e-243 785.0
PYH2_k127_8449427_1 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 547.0
PYH2_k127_8449427_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000009829 171.0
PYH2_k127_8449427_11 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000001634 126.0
PYH2_k127_8449427_12 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.000000000000000000000000003485 123.0
PYH2_k127_8449427_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000006756 109.0
PYH2_k127_8449427_14 - - - - 0.000000000000000005787 86.0
PYH2_k127_8449427_15 exporters of the RND superfamily K07003 - - 0.00000000000004952 75.0
PYH2_k127_8449427_16 metallopeptidase activity K01317 - 3.4.21.10 0.0000000000002982 83.0
PYH2_k127_8449427_17 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000006422 78.0
PYH2_k127_8449427_18 Planctomycete cytochrome C - - - 0.00000000843 69.0
PYH2_k127_8449427_19 Belongs to the eIF-2B alpha beta delta subunits family K08963 - 5.3.1.23 0.000007489 54.0
PYH2_k127_8449427_2 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 503.0
PYH2_k127_8449427_21 mRNA capping enzyme, beta chain protein - - - 0.0005061 44.0
PYH2_k127_8449427_3 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 315.0
PYH2_k127_8449427_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 310.0
PYH2_k127_8449427_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
PYH2_k127_8449427_6 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000245 241.0
PYH2_k127_8449427_7 Kelch motif - - - 0.00000000000000000000000000000000000000000000000008392 201.0
PYH2_k127_8449427_8 B12 binding domain - - - 0.0000000000000000000000000000000000000000001889 173.0
PYH2_k127_8449427_9 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000007347 174.0
PYH2_k127_8468848_0 2 heme-binding sites K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 462.0
PYH2_k127_8468848_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 387.0
PYH2_k127_8468848_2 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 393.0
PYH2_k127_8468848_3 PFAM aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
PYH2_k127_8468848_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 275.0
PYH2_k127_8468848_5 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000006631 204.0
PYH2_k127_8468848_6 - - - - 0.00000000000000000000000001285 117.0
PYH2_k127_8468848_7 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000301 96.0
PYH2_k127_8468848_8 cellulose binding - - - 0.0000001998 55.0
PYH2_k127_846894_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 556.0
PYH2_k127_846894_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 488.0
PYH2_k127_846894_2 Transcriptional regulator K03655,K10439,K11708 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 493.0
PYH2_k127_846894_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 383.0
PYH2_k127_846894_4 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 302.0
PYH2_k127_846894_5 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 292.0
PYH2_k127_846894_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000002526 234.0
PYH2_k127_846894_7 Proteolipid membrane potential modulator - - - 0.00000000000000007992 81.0
PYH2_k127_84915_0 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000003541 234.0
PYH2_k127_84915_1 Tetratricopeptide repeat - - - 0.00000000000000006304 86.0
PYH2_k127_84915_2 to Saccharomyces cerevisiae TOM71 (YHR117W) and TOM70 (YNL121C) K17768 GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0017038,GO:0019867,GO:0030150,GO:0030943,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0045039,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:0090151,GO:0098573,GO:0098588,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1990542 - 0.00008936 55.0
PYH2_k127_8498912_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 439.0
PYH2_k127_8498912_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000001048 121.0
PYH2_k127_8498912_2 HYR domain - - - 0.0000000000000000000000349 110.0
PYH2_k127_8514927_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000006477 269.0
PYH2_k127_8514927_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000366 208.0
PYH2_k127_8514927_2 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000003893 194.0
PYH2_k127_8514927_3 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K00595 - 2.1.1.132 0.000000000000000000000000000000000003851 143.0
PYH2_k127_8549391_0 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 363.0
PYH2_k127_8549391_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 331.0
PYH2_k127_8549391_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003886 261.0
PYH2_k127_8549391_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000001089 78.0
PYH2_k127_8556549_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.362e-256 797.0
PYH2_k127_8556549_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 560.0
PYH2_k127_8556549_2 Pterin binding enzyme K15023 - 2.1.1.258 0.00000002945 55.0
PYH2_k127_859168_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 512.0
PYH2_k127_859168_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 361.0
PYH2_k127_859168_10 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000136 99.0
PYH2_k127_859168_11 protein histidine kinase activity - - - 0.000000001842 70.0
PYH2_k127_859168_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 359.0
PYH2_k127_859168_3 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001053 254.0
PYH2_k127_859168_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000002395 242.0
PYH2_k127_859168_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000003974 204.0
PYH2_k127_859168_6 acetyltransferase K18815 - 2.3.1.82 0.00000000000000000000000000000001987 134.0
PYH2_k127_859168_7 - - - - 0.0000000000000000000000000000004421 134.0
PYH2_k127_859168_8 Epimerase dehydratase K01710 - 4.2.1.46 0.0000000000000000000339 104.0
PYH2_k127_859168_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000001604 102.0
PYH2_k127_863808_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 9.393e-302 932.0
PYH2_k127_863808_1 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 411.0
PYH2_k127_863808_2 NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 323.0
PYH2_k127_863808_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001996 282.0
PYH2_k127_863808_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002644 239.0
PYH2_k127_863808_5 Domain of unknown function (DUF4404) - - - 0.0000000000000000000000000000000006061 133.0
PYH2_k127_863808_6 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000377 130.0
PYH2_k127_8667542_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000677 193.0
PYH2_k127_8667542_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000003151 176.0
PYH2_k127_8667542_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000004163 63.0
PYH2_k127_8682323_0 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.00000000000000000000000006428 108.0
PYH2_k127_8682323_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000194 98.0
PYH2_k127_8682323_2 cheY-homologous receiver domain - - - 0.0000000000000000003933 94.0
PYH2_k127_8686913_0 GXGXG motif - - - 0.0 1175.0
PYH2_k127_8686913_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 603.0
PYH2_k127_8686913_2 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005087 280.0
PYH2_k127_8686913_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000003617 233.0
PYH2_k127_8731101_0 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 402.0
PYH2_k127_8731101_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 380.0
PYH2_k127_8731101_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 310.0
PYH2_k127_8731101_3 Thymidylate synthase K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000003212 261.0
PYH2_k127_8735658_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.75e-203 649.0
PYH2_k127_8735658_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 456.0
PYH2_k127_8735658_2 Transposase IS116 IS110 IS902 family - - - 0.000000000000000001285 93.0
PYH2_k127_8766722_0 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000004451 181.0
PYH2_k127_8766722_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000006236 124.0
PYH2_k127_8766722_2 Major facilitator superfamily - - - 0.0000000000000000000000001763 117.0
PYH2_k127_8779833_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 458.0
PYH2_k127_8779833_1 negative regulation of hydrogen peroxide metabolic process K01388,K01394,K01396,K01402,K07763,K07994,K07999 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0009719,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010310,GO:0010646,GO:0010648,GO:0010727,GO:0010941,GO:0010942,GO:0016043,GO:0016787,GO:0017171,GO:0019221,GO:0019222,GO:0019538,GO:0022411,GO:0022617,GO:0023051,GO:0023052,GO:0023057,GO:0030163,GO:0030198,GO:0030334,GO:0030335,GO:0030425,GO:0030574,GO:0031012,GO:0031323,GO:0031324,GO:0031334,GO:0032459,GO:0032461,GO:0032879,GO:0032963,GO:0032991,GO:0033554,GO:0034097,GO:0034599,GO:0034614,GO:0035690,GO:0036477,GO:0040012,GO:0040017,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043200,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0044087,GO:0044089,GO:0044238,GO:0044297,GO:0044421,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051193,GO:0051195,GO:0051270,GO:0051272,GO:0051716,GO:0051896,GO:0051898,GO:0065007,GO:0070011,GO:0070887,GO:0071229,GO:0071230,GO:0071241,GO:0071310,GO:0071345,GO:0071417,GO:0071495,GO:0071704,GO:0071731,GO:0071732,GO:0071840,GO:0080134,GO:0080135,GO:0097366,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:0140096,GO:1900407,GO:1900409,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902531,GO:1902532,GO:1902882,GO:1902884,GO:1903201,GO:1903209,GO:2000145,GO:2000147,GO:2000377,GO:2000378 3.4.24.17,3.4.24.22,3.4.24.34,3.4.24.7,3.4.24.80 0.000000402 61.0
PYH2_k127_8798983_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 398.0
PYH2_k127_8798983_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 338.0
PYH2_k127_8798983_2 COG2801 Transposase and inactivated derivatives K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
PYH2_k127_8798983_3 COG2963 Transposase and inactivated derivatives - - - 0.0000000001359 67.0
PYH2_k127_8805288_0 PFAM MgsA AAA ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 551.0
PYH2_k127_8805288_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
PYH2_k127_8805288_2 Protein of unknown function (DUF1285) K09986 - - 0.0000000000000000000000006594 110.0
PYH2_k127_8805288_3 von Willebrand factor type A domain K07114 - - 0.000000566 54.0
PYH2_k127_8819842_0 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 496.0
PYH2_k127_8819842_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 496.0
PYH2_k127_8819842_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 299.0
PYH2_k127_8819842_3 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006401 261.0
PYH2_k127_8819842_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000003936 235.0
PYH2_k127_8825202_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 378.0
PYH2_k127_8825202_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000000000000000001651 178.0
PYH2_k127_8825202_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000567 100.0
PYH2_k127_8825202_3 Histidine kinase - - - 0.00000000000000000008351 90.0
PYH2_k127_8825202_4 Flavodoxin-like fold - - - 0.000000000000000005912 92.0
PYH2_k127_8842928_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 417.0
PYH2_k127_8842928_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 315.0
PYH2_k127_8842928_2 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000002492 161.0
PYH2_k127_8861341_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000002101 192.0
PYH2_k127_8861341_1 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000003027 136.0
PYH2_k127_8864078_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000002501 162.0
PYH2_k127_8864078_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001426 144.0
PYH2_k127_8864078_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000001659 121.0
PYH2_k127_8878877_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.383e-262 821.0
PYH2_k127_8878877_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.072e-227 714.0
PYH2_k127_8878877_10 YbbR-like protein - - - 0.00000000000000000000000000001159 130.0
PYH2_k127_8878877_11 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000008401 85.0
PYH2_k127_8878877_2 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 552.0
PYH2_k127_8878877_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 479.0
PYH2_k127_8878877_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 304.0
PYH2_k127_8878877_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 302.0
PYH2_k127_8878877_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000196 257.0
PYH2_k127_8878877_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000004175 170.0
PYH2_k127_8878877_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000004389 139.0
PYH2_k127_8878877_9 Amidohydrolase - - - 0.000000000000000000000000000000006662 139.0
PYH2_k127_8880206_0 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 358.0
PYH2_k127_8880206_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000008713 235.0
PYH2_k127_8880206_2 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770 - 2.7.1.202 0.00000000000000000000000001223 127.0
PYH2_k127_8891250_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000003075 193.0
PYH2_k127_8891250_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000002533 64.0
PYH2_k127_8911033_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1041.0
PYH2_k127_8911033_1 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 1.976e-275 869.0
PYH2_k127_8911033_2 Domain of unknown function (DUF4139) - - - 0.000000000001088 70.0
PYH2_k127_8931278_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 6.226e-199 638.0
PYH2_k127_8931278_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 539.0
PYH2_k127_8931278_10 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000000000000000002324 104.0
PYH2_k127_8931278_11 - - - - 0.000008339 52.0
PYH2_k127_8931278_2 Proton-conducting membrane transporter K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
PYH2_k127_8931278_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 429.0
PYH2_k127_8931278_4 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 355.0
PYH2_k127_8931278_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000000000006369 158.0
PYH2_k127_8931278_6 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.0000000000000000000000000000000000000003337 153.0
PYH2_k127_8931278_7 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000000005579 156.0
PYH2_k127_8931278_8 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000000000000000005555 129.0
PYH2_k127_8931278_9 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000000000000000173 102.0
PYH2_k127_8959620_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000105 176.0
PYH2_k127_8959620_1 - - - - 0.00000000000000000000000000002563 123.0
PYH2_k127_8959620_2 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000001108 109.0
PYH2_k127_8974008_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000004513 141.0
PYH2_k127_8974008_1 PFAM von Willebrand factor type A K07114 - - 0.0000001443 64.0
PYH2_k127_9006973_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
PYH2_k127_9006973_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
PYH2_k127_9006973_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000001255 228.0
PYH2_k127_9006973_3 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.0000000000000000000000000000000001344 142.0
PYH2_k127_9006973_4 FAD binding domain - - - 0.00000000000000000000000000000006099 140.0
PYH2_k127_9010198_0 Elongation factor Tu domain 2 K03833 - - 1.646e-203 653.0
PYH2_k127_9010198_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
PYH2_k127_9010198_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000002846 152.0
PYH2_k127_9010198_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000001604 108.0
PYH2_k127_9073886_0 4 iron, 4 sulfur cluster binding K00338 - 1.6.5.3 0.0000000000216 67.0
PYH2_k127_9073886_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000001204 69.0
PYH2_k127_9073886_2 4Fe-4S dicluster domain - - - 0.00000001202 59.0
PYH2_k127_9073886_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00001608 50.0
PYH2_k127_9073886_4 Ferredoxin-dependent bilin reductase K08101 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0010019,GO:0016491,GO:0016627,GO:0016636,GO:0023052,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050619,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007 1.3.7.4 0.0004928 51.0
PYH2_k127_9106698_0 ATP synthase alpha beta family, nucleotide-binding domain K02412,K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 561.0
PYH2_k127_9106698_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 542.0
PYH2_k127_9106698_10 repeat-containing protein - - - 0.0000000000000000000000001913 124.0
PYH2_k127_9106698_11 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000004136 98.0
PYH2_k127_9106698_12 Flagellar assembly protein FliH K02411 - - 0.00000000000000000003731 100.0
PYH2_k127_9106698_2 Bacterial regulatory protein, Fis family K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 431.0
PYH2_k127_9106698_3 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 400.0
PYH2_k127_9106698_4 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
PYH2_k127_9106698_5 FliG middle domain K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006566 272.0
PYH2_k127_9106698_6 phosphorelay sensor kinase activity K07708,K07710,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000004493 248.0
PYH2_k127_9106698_7 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000002093 168.0
PYH2_k127_9106698_8 Formyl transferase - - - 0.00000000000000000000000003562 111.0
PYH2_k127_9106698_9 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000001282 111.0
PYH2_k127_9108114_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.338e-202 658.0
PYH2_k127_9108114_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 323.0
PYH2_k127_9108114_2 membrane K08978 - - 0.00000000000000000000000000001317 122.0
PYH2_k127_9108114_3 self proteolysis - - - 0.0000000000000000000000000001017 125.0
PYH2_k127_9108114_4 Yqey-like protein K09117 - - 0.000000000000000000000001805 108.0
PYH2_k127_9108114_5 - - - - 0.000000000000000000000002709 104.0
PYH2_k127_9108114_6 Thrombospondin type 3 - - - 0.000000000000000003701 96.0
PYH2_k127_9108114_7 - - - - 0.0002323 49.0
PYH2_k127_9111997_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 306.0
PYH2_k127_9111997_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000295 267.0
PYH2_k127_9111997_2 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.000000000000000000000000000000000000000000000000000000000000000000000000005326 269.0
PYH2_k127_9111997_3 Protein of unknown function (DUF3641) - - - 0.00000000001096 68.0
PYH2_k127_9147419_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000005619 249.0
PYH2_k127_9147419_1 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
PYH2_k127_9147419_2 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
PYH2_k127_9147419_3 Flavodoxin - - - 0.00000005624 61.0
PYH2_k127_9150267_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.534e-265 834.0
PYH2_k127_9150267_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000001961 97.0
PYH2_k127_9150267_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00001736 49.0
PYH2_k127_9153527_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 532.0
PYH2_k127_9153527_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 362.0
PYH2_k127_9153527_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 291.0
PYH2_k127_9153527_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000009084 204.0
PYH2_k127_9153527_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000007671 162.0
PYH2_k127_9153527_5 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000006944 124.0
PYH2_k127_9153527_6 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001705 110.0
PYH2_k127_9153527_7 DDE superfamily endonuclease K07494 - - 0.00000000004777 63.0
PYH2_k127_91655_0 type II secretion system K02454 - - 7.388e-203 647.0
PYH2_k127_91655_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000003198 98.0
PYH2_k127_9178134_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.851e-252 792.0
PYH2_k127_9178134_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 325.0
PYH2_k127_9178134_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001757 285.0
PYH2_k127_9178134_3 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006047 257.0
PYH2_k127_9178134_4 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000008887 158.0
PYH2_k127_9178134_5 YGGT family K02221 - - 0.00000000000000000000000000000004863 128.0
PYH2_k127_9178134_6 DivIVA protein K04074 - - 0.000000000000000000000000156 112.0
PYH2_k127_9178134_7 DUF167 K09131 - - 0.000000000000000000000005153 104.0
PYH2_k127_9178134_8 NADPH-dependent FMN reductase - - - 0.000000000000000000000006497 113.0
PYH2_k127_9188253_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 458.0
PYH2_k127_9188253_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 390.0
PYH2_k127_9188253_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000001644 112.0
PYH2_k127_9188253_3 - - - - 0.00000000000000000000732 101.0
PYH2_k127_9188253_4 - - - - 0.00000000009005 66.0
PYH2_k127_9188253_5 CobQ CobB MinD ParA nucleotide binding domain - - - 0.0001109 53.0
PYH2_k127_9234623_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.009e-240 766.0
PYH2_k127_9234623_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 422.0
PYH2_k127_9234623_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 404.0
PYH2_k127_9234623_3 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008355 263.0
PYH2_k127_9234623_4 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
PYH2_k127_9234623_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000004641 111.0
PYH2_k127_9234623_6 HupF/HypC family K04653 - - 0.0000000000000000876 83.0
PYH2_k127_9234623_7 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000001676 82.0
PYH2_k127_9234623_8 - - - - 0.00001571 55.0
PYH2_k127_9237990_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 369.0
PYH2_k127_9237990_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 329.0
PYH2_k127_9237990_2 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000006657 216.0
PYH2_k127_9237990_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000009723 213.0
PYH2_k127_9237990_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000165 183.0
PYH2_k127_9237990_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000001614 130.0
PYH2_k127_9237990_6 LysM domain - - - 0.000000000000000006987 94.0
PYH2_k127_9237990_7 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.0000000000003719 74.0
PYH2_k127_9271808_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.128e-287 906.0
PYH2_k127_9271808_1 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000003571 199.0
PYH2_k127_9282615_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 474.0
PYH2_k127_9282615_1 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000006265 163.0
PYH2_k127_9294985_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.24e-306 967.0
PYH2_k127_9294985_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000004115 238.0
PYH2_k127_9294985_2 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000001017 185.0
PYH2_k127_9294985_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000006095 160.0
PYH2_k127_9323546_0 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
PYH2_k127_9323546_1 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000005741 154.0
PYH2_k127_9323546_2 Glycolate oxidase subunit K00104 - 1.1.3.15 0.0000000000000000000000000000001005 141.0
PYH2_k127_9323546_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000002435 103.0
PYH2_k127_9323546_4 FAD linked oxidase domain protein - - - 0.00000004255 55.0