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Overview

ID MAG03194
Name PYH2_bin.46
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 59.56
Contamination (%) 1.77
GC content (%) 69.0
N50 (bp) 3,344
Genome size (bp) 1,762,628

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1933

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1002617_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 591.0
PYH2_k127_1002617_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000002719 228.0
PYH2_k127_1002617_2 - - - - 0.000000000000000000000000000000000000005218 158.0
PYH2_k127_1002617_3 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000008561 132.0
PYH2_k127_1002617_4 Ion channel - - - 0.0000000000000002405 88.0
PYH2_k127_1006092_0 UDP binding domain K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 504.0
PYH2_k127_1006092_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 427.0
PYH2_k127_1006092_2 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 392.0
PYH2_k127_1017715_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 606.0
PYH2_k127_1017715_1 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 442.0
PYH2_k127_1017715_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 408.0
PYH2_k127_1017715_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000002401 235.0
PYH2_k127_1017715_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001003 237.0
PYH2_k127_1017715_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000002307 143.0
PYH2_k127_1026767_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1187.0
PYH2_k127_1026767_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000005437 259.0
PYH2_k127_1059180_0 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 523.0
PYH2_k127_1059180_1 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 377.0
PYH2_k127_1075150_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 322.0
PYH2_k127_1075150_1 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001136 288.0
PYH2_k127_1084126_0 Belongs to the HypD family K04654 - - 2.347e-198 627.0
PYH2_k127_1084126_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 583.0
PYH2_k127_1084126_2 Formyl transferase K19640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004421 239.0
PYH2_k127_1084126_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000002033 196.0
PYH2_k127_1084126_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000001181 117.0
PYH2_k127_109411_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 375.0
PYH2_k127_109411_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000006612 187.0
PYH2_k127_109411_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000000000000000000000000002107 154.0
PYH2_k127_109411_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000001989 50.0
PYH2_k127_1094707_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 525.0
PYH2_k127_1094707_1 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
PYH2_k127_1094707_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 379.0
PYH2_k127_1094707_3 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 358.0
PYH2_k127_1094707_4 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
PYH2_k127_1095219_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 379.0
PYH2_k127_1095219_1 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 323.0
PYH2_k127_1095219_2 Iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001707 221.0
PYH2_k127_1095219_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000001214 162.0
PYH2_k127_1097838_0 polyphosphate kinase - - - 3.911e-230 722.0
PYH2_k127_1097838_1 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000003676 87.0
PYH2_k127_1130736_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1127.0
PYH2_k127_1136760_0 Sulfate transporter antisigma-factor antagonist STAS - - - 7.489e-298 929.0
PYH2_k127_1136760_1 STAS domain K03321 - - 1.505e-231 733.0
PYH2_k127_1136760_2 Chromate resistance exported protein - - - 0.0000000000000000000000000000000005695 140.0
PYH2_k127_1141364_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1414.0
PYH2_k127_1141364_1 24 kD subunit K00122 - 1.17.1.9 2.789e-276 859.0
PYH2_k127_1141364_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000003428 91.0
PYH2_k127_1144537_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 4.412e-194 611.0
PYH2_k127_1144537_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 437.0
PYH2_k127_1144537_2 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000006803 145.0
PYH2_k127_1147788_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 9.642e-274 854.0
PYH2_k127_1147788_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 602.0
PYH2_k127_1147788_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
PYH2_k127_1147788_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
PYH2_k127_1147788_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 265.0
PYH2_k127_1147788_5 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000006199 135.0
PYH2_k127_1147788_6 Thioredoxin K05838 - - 0.0000000000000000001908 89.0
PYH2_k127_1167962_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
PYH2_k127_1167962_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 299.0
PYH2_k127_1167962_2 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
PYH2_k127_1167962_3 Rubredoxin - - - 0.0000000000000000000000003837 118.0
PYH2_k127_1167962_4 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000003585 59.0
PYH2_k127_1167962_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00001655 49.0
PYH2_k127_1179760_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1123.0
PYH2_k127_1179760_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
PYH2_k127_1179760_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 385.0
PYH2_k127_1179760_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000002164 89.0
PYH2_k127_1195998_0 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 433.0
PYH2_k127_1195998_1 glycosyl transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000222 262.0
PYH2_k127_1195998_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000002141 208.0
PYH2_k127_1196532_0 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 2.074e-208 660.0
PYH2_k127_1196532_1 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 466.0
PYH2_k127_1196532_2 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000002261 143.0
PYH2_k127_1196532_3 PFAM molydopterin dinucleotide-binding region K00203,K00336 - 1.2.7.12,1.6.5.3 0.00000000000000003861 85.0
PYH2_k127_1209916_0 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 504.0
PYH2_k127_1209916_1 - - - - 0.00005159 46.0
PYH2_k127_1214031_0 synthetase K01895 - 6.2.1.1 1.075e-241 754.0
PYH2_k127_1214031_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 502.0
PYH2_k127_1214031_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 477.0
PYH2_k127_1214031_3 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000002872 171.0
PYH2_k127_1214031_4 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000004047 128.0
PYH2_k127_1221503_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 445.0
PYH2_k127_1221503_1 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 336.0
PYH2_k127_1221503_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 325.0
PYH2_k127_1221503_3 Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
PYH2_k127_1221503_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000005956 241.0
PYH2_k127_1221503_5 ThiS family K03154 - - 0.000000000000000000002249 95.0
PYH2_k127_1222315_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1150.0
PYH2_k127_1222315_1 PFAM heat shock protein DnaJ domain protein K05516 - - 0.00000000000000000000000000000000000000000000004202 174.0
PYH2_k127_1222315_2 DNA recombination-mediator protein A K04096 - - 0.00002042 46.0
PYH2_k127_1243483_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 303.0
PYH2_k127_1243483_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000669 261.0
PYH2_k127_1243483_2 Bacterial transcriptional repressor - - - 0.00004633 46.0
PYH2_k127_1260650_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.821e-198 623.0
PYH2_k127_1260650_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 582.0
PYH2_k127_1260650_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
PYH2_k127_1260650_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000003086 196.0
PYH2_k127_1262898_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 602.0
PYH2_k127_1262898_1 FixH K09926 - - 0.00000000000000000000002226 110.0
PYH2_k127_1281666_0 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 321.0
PYH2_k127_1281666_1 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006402 264.0
PYH2_k127_1281666_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001001 229.0
PYH2_k127_1283090_0 Heat shock 70 kDa protein K04043 - - 2.036e-321 993.0
PYH2_k127_1283090_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 606.0
PYH2_k127_1283090_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 541.0
PYH2_k127_1283090_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 494.0
PYH2_k127_1283090_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
PYH2_k127_1283090_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000004758 178.0
PYH2_k127_1283090_6 PFAM membrane protein of K08972 - - 0.0000000000000000000000000000000000000253 148.0
PYH2_k127_1283090_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000001983 113.0
PYH2_k127_1283090_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000007844 62.0
PYH2_k127_1306368_0 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 488.0
PYH2_k127_1306368_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 313.0
PYH2_k127_1306368_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000007406 98.0
PYH2_k127_1312504_0 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
PYH2_k127_1312504_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000002631 236.0
PYH2_k127_1312504_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0001527 46.0
PYH2_k127_1318577_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 405.0
PYH2_k127_1318577_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003018 173.0
PYH2_k127_1318577_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000001328 140.0
PYH2_k127_1318577_3 peptidase, M23 - - - 0.0000958 51.0
PYH2_k127_1333688_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 567.0
PYH2_k127_1333688_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
PYH2_k127_1333688_2 - - - - 0.00000000000000000004055 95.0
PYH2_k127_1333688_3 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.000000000267 62.0
PYH2_k127_1345195_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 478.0
PYH2_k127_1345195_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
PYH2_k127_1349444_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 6.012e-316 975.0
PYH2_k127_1349444_1 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000124 88.0
PYH2_k127_1353007_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 506.0
PYH2_k127_1353007_1 - - - - 0.00000000000000000000000000001202 118.0
PYH2_k127_135740_0 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 271.0
PYH2_k127_135740_1 AsmA family K07289,K07290 - - 0.00000000000000000000004064 115.0
PYH2_k127_1359645_0 PFAM response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000000000008895 230.0
PYH2_k127_1359645_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000005124 207.0
PYH2_k127_1359645_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000001147 113.0
PYH2_k127_1374503_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 560.0
PYH2_k127_1374503_1 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000001592 154.0
PYH2_k127_1374503_2 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000004818 156.0
PYH2_k127_1374503_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000001392 137.0
PYH2_k127_1374503_4 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000001395 68.0
PYH2_k127_1386714_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 282.0
PYH2_k127_1386714_1 - - - - 0.0000000000000000000000000000000000000000000000003428 186.0
PYH2_k127_1386714_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000002016 177.0
PYH2_k127_1393821_0 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 361.0
PYH2_k127_1393821_1 FMN_bind K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000465 249.0
PYH2_k127_1393821_2 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000009683 228.0
PYH2_k127_139794_0 PFAM carboxyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 528.0
PYH2_k127_139794_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001993 257.0
PYH2_k127_139794_2 Oxaloacetate decarboxylase, gamma chain - - - 0.00000234 50.0
PYH2_k127_1413309_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 520.0
PYH2_k127_1413309_1 extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 431.0
PYH2_k127_1413309_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000002732 197.0
PYH2_k127_1421761_0 Molybdopterin oxidoreductase Fe4S4 domain K00372,K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 477.0
PYH2_k127_1426645_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 525.0
PYH2_k127_1426645_1 - - - - 0.00000000421 60.0
PYH2_k127_1438391_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000001451 182.0
PYH2_k127_1441559_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000269 207.0
PYH2_k127_1441559_1 - - - - 0.0000000000000000000000000000000000000000000000000000008538 200.0
PYH2_k127_1441559_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000003993 177.0
PYH2_k127_1455970_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.001e-204 643.0
PYH2_k127_1455970_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
PYH2_k127_1455970_2 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003497 269.0
PYH2_k127_1455970_3 Rhodanese Homology Domain - - - 0.0000000000000000000000006071 108.0
PYH2_k127_1467179_0 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 611.0
PYH2_k127_1467179_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
PYH2_k127_1467179_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
PYH2_k127_1467179_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 255.0
PYH2_k127_1467179_4 protein conserved in bacteria K07028 - - 0.0000000000000000000000000000000003958 143.0
PYH2_k127_1467179_5 Universal stress protein family - - - 0.00000000000000000000000000000002717 131.0
PYH2_k127_1467179_6 - - - - 0.00000000000000000000000000000217 136.0
PYH2_k127_1488626_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
PYH2_k127_1488626_1 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000004705 205.0
PYH2_k127_1488626_2 Histidine kinase K19661 - 2.7.13.3 0.00000000000000000000000000002218 128.0
PYH2_k127_1488626_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000002573 58.0
PYH2_k127_1496208_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.179e-236 742.0
PYH2_k127_1496208_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 427.0
PYH2_k127_1496208_2 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004876 276.0
PYH2_k127_1496208_3 - - - - 0.0000000001112 64.0
PYH2_k127_1505412_0 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 303.0
PYH2_k127_1505412_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008389 299.0
PYH2_k127_1505412_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003661 244.0
PYH2_k127_1505412_3 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
PYH2_k127_1527326_0 MMPL family - - - 0.0 1336.0
PYH2_k127_1527326_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 329.0
PYH2_k127_1527326_2 transcriptional regulator - - - 0.0000000000000000000000000000000000003061 141.0
PYH2_k127_1529609_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 401.0
PYH2_k127_1529609_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000002955 226.0
PYH2_k127_1529609_2 Universal stress protein - - - 0.0000000000000000000000000000000000215 143.0
PYH2_k127_1529609_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000001473 119.0
PYH2_k127_1541177_0 Esterase of the alpha-beta hydrolase superfamily - - - 2.273e-210 678.0
PYH2_k127_1541177_1 Tetratricopeptide repeat - - - 3.465e-203 644.0
PYH2_k127_1541177_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001376 224.0
PYH2_k127_1541177_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001285 221.0
PYH2_k127_1541177_4 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000001329 143.0
PYH2_k127_1541177_5 - - - - 0.000000000000000000000000001036 125.0
PYH2_k127_1541177_6 transcriptional regulator, SARP family - - - 0.000002324 59.0
PYH2_k127_1541177_7 TIR domain - - - 0.00009022 54.0
PYH2_k127_1544255_0 Acyl-CoA dehydrogenase N terminal K20035 - - 5.913e-234 733.0
PYH2_k127_1544255_1 electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000401 244.0
PYH2_k127_1561957_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.505e-210 664.0
PYH2_k127_1561957_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 406.0
PYH2_k127_1561957_2 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001169 248.0
PYH2_k127_1561957_3 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002583 224.0
PYH2_k127_1561957_4 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000002903 179.0
PYH2_k127_1562205_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 454.0
PYH2_k127_1562205_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000006849 262.0
PYH2_k127_1562205_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000189 161.0
PYH2_k127_1562205_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000002357 121.0
PYH2_k127_1595810_0 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 304.0
PYH2_k127_1595810_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000001926 218.0
PYH2_k127_1598579_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004466 277.0
PYH2_k127_1598579_1 Regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase phosphorylase K13641 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000006539 210.0
PYH2_k127_1615249_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 6.832e-298 923.0
PYH2_k127_1615249_1 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 508.0
PYH2_k127_1615249_2 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000007614 195.0
PYH2_k127_1615249_3 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000005587 151.0
PYH2_k127_1615249_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000001375 101.0
PYH2_k127_1615249_5 AI-2E family transporter - - - 0.000000000004607 72.0
PYH2_k127_1645113_0 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 531.0
PYH2_k127_1645113_1 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 352.0
PYH2_k127_169667_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 430.0
PYH2_k127_169667_1 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
PYH2_k127_169667_2 SCP-2 sterol transfer family - - - 0.00000000000000000000133 96.0
PYH2_k127_1727197_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 521.0
PYH2_k127_1727197_1 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000002 206.0
PYH2_k127_1727197_2 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000006832 105.0
PYH2_k127_1741177_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 347.0
PYH2_k127_1741177_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
PYH2_k127_1741177_2 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000005224 201.0
PYH2_k127_1767480_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 2.964e-292 900.0
PYH2_k127_1767480_1 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
PYH2_k127_1767480_2 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000007399 132.0
PYH2_k127_1780067_0 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
PYH2_k127_1780067_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 410.0
PYH2_k127_1780067_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
PYH2_k127_1780067_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 383.0
PYH2_k127_1780067_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
PYH2_k127_1780067_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000002907 249.0
PYH2_k127_1792122_0 aminopeptidase N K01256 - 3.4.11.2 1.222e-222 698.0
PYH2_k127_1792122_1 - - - - 0.0000000000000000000000000000000000000001052 169.0
PYH2_k127_1792122_2 Divalent cation transporter K06213 - - 0.0000000000000001024 80.0
PYH2_k127_1796587_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.313e-272 847.0
PYH2_k127_1796587_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 615.0
PYH2_k127_1796587_2 dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 299.0
PYH2_k127_1796587_3 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000006027 149.0
PYH2_k127_1826829_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 561.0
PYH2_k127_1826829_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 552.0
PYH2_k127_1826829_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 463.0
PYH2_k127_1826829_3 Protein of unknown function (DUF721) - - - 0.000000000000000009686 92.0
PYH2_k127_1830125_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 493.0
PYH2_k127_1830125_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 392.0
PYH2_k127_1859768_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 446.0
PYH2_k127_1865876_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.03e-232 726.0
PYH2_k127_1865876_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
PYH2_k127_1865876_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
PYH2_k127_1865876_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002521 267.0
PYH2_k127_1865876_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000002436 134.0
PYH2_k127_1865876_5 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000002042 119.0
PYH2_k127_1876643_0 Outer membrane protein beta-barrel family - - - 5.827e-210 664.0
PYH2_k127_1887500_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.812e-261 824.0
PYH2_k127_1887500_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 407.0
PYH2_k127_1887500_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001437 242.0
PYH2_k127_1887500_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
PYH2_k127_1887500_4 - - - - 0.000000000000001389 79.0
PYH2_k127_1893674_0 ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 483.0
PYH2_k127_1893674_1 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 319.0
PYH2_k127_1893674_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000002595 95.0
PYH2_k127_1904132_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 488.0
PYH2_k127_1904132_1 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000002015 214.0
PYH2_k127_1904132_2 Cytochrome c K08738 - - 0.0000000000000000000000000000001125 132.0
PYH2_k127_1904132_3 Pfam cytochrome c K08738 - - 0.000000000000000000000001668 108.0
PYH2_k127_1936855_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 339.0
PYH2_k127_1936855_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000007631 171.0
PYH2_k127_1936855_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000003386 147.0
PYH2_k127_196254_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.676e-203 654.0
PYH2_k127_1964539_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1569.0
PYH2_k127_1964539_1 Sugar (and other) transporter - - - 7.398e-201 638.0
PYH2_k127_1964539_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 463.0
PYH2_k127_1964539_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
PYH2_k127_1964539_4 MOFRL family K11529 - 2.7.1.165 0.0000000000002829 84.0
PYH2_k127_1990248_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 567.0
PYH2_k127_1990248_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 517.0
PYH2_k127_1990248_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 457.0
PYH2_k127_1990248_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 273.0
PYH2_k127_1990248_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
PYH2_k127_1990248_5 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
PYH2_k127_1990248_6 Protein of unknown function (DUF2788) - - - 0.000000000000000000000006778 102.0
PYH2_k127_2061561_0 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 452.0
PYH2_k127_2061561_1 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 416.0
PYH2_k127_2073187_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000008951 175.0
PYH2_k127_2073187_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000105 52.0
PYH2_k127_2073187_2 - - - - 0.0004226 45.0
PYH2_k127_2089487_0 Type 4 fimbrial biogenesis protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 384.0
PYH2_k127_2089487_1 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006384 250.0
PYH2_k127_2089487_2 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000002635 180.0
PYH2_k127_2102411_0 AMP-binding enzyme C-terminal domain K00666 - - 2.623e-282 874.0
PYH2_k127_2102411_1 ABC transporter K01999 - - 4.343e-198 624.0
PYH2_k127_2102411_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 493.0
PYH2_k127_2102411_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 444.0
PYH2_k127_2102411_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
PYH2_k127_2102411_5 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 393.0
PYH2_k127_2102411_6 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 380.0
PYH2_k127_2102411_7 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000006571 188.0
PYH2_k127_2102411_8 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000005688 183.0
PYH2_k127_2102411_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000002045 55.0
PYH2_k127_2138263_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.436e-251 781.0
PYH2_k127_2138263_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 281.0
PYH2_k127_2138263_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002756 275.0
PYH2_k127_2172394_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1428.0
PYH2_k127_2172394_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 475.0
PYH2_k127_2172394_2 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 471.0
PYH2_k127_2172394_3 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 383.0
PYH2_k127_2173233_0 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000001208 162.0
PYH2_k127_2190342_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1089.0
PYH2_k127_2190342_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
PYH2_k127_2190342_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000002315 199.0
PYH2_k127_21995_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
PYH2_k127_21995_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
PYH2_k127_21995_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000001069 174.0
PYH2_k127_21995_3 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000002484 111.0
PYH2_k127_2202698_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1641.0
PYH2_k127_2202698_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002059 171.0
PYH2_k127_2202698_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000001421 87.0
PYH2_k127_2211095_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2055.0
PYH2_k127_2211095_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 320.0
PYH2_k127_2217995_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 303.0
PYH2_k127_2217995_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 293.0
PYH2_k127_2217995_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004889 265.0
PYH2_k127_2218512_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1052.0
PYH2_k127_2219955_0 chemotaxis K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 490.0
PYH2_k127_2219955_1 Histidine kinase K02487,K06596 - - 0.000000000000003214 79.0
PYH2_k127_2230585_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 389.0
PYH2_k127_2230585_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000003593 198.0
PYH2_k127_2230585_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000001373 188.0
PYH2_k127_2230585_3 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000001403 136.0
PYH2_k127_2230585_4 Phospholipase, patatin family K07001 - - 0.0000000002353 61.0
PYH2_k127_2234299_0 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 313.0
PYH2_k127_2234299_1 Member of a two-component regulatory system K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 295.0
PYH2_k127_2234299_2 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
PYH2_k127_2234299_3 - K09004 - - 0.0000000000000000000000000000000000000000000000000000000002402 208.0
PYH2_k127_2249439_0 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 455.0
PYH2_k127_2249439_1 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000054 259.0
PYH2_k127_2249439_2 Protein of unknown function (DUF2863) - - - 0.000000000000000000000000000000000000000000000000001761 184.0
PYH2_k127_2249439_3 YCII-related domain K09780 - - 0.000000000000001257 86.0
PYH2_k127_2267807_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 573.0
PYH2_k127_2267807_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
PYH2_k127_2267807_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000007803 189.0
PYH2_k127_2267807_3 Trypsin - - - 0.0000000000000000000000000000000000000000000000004805 193.0
PYH2_k127_2267807_4 - - - - 0.000000000000000000000000000000000000000006438 161.0
PYH2_k127_2267807_5 DsrC like protein - - - 0.0000000000000000000000000000000000000001808 157.0
PYH2_k127_2267807_6 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000004346 143.0
PYH2_k127_2267807_7 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003768 109.0
PYH2_k127_2267807_8 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000361 93.0
PYH2_k127_2267807_9 Bacterial protein of unknown function (DUF853) K06915 - - 0.000002832 49.0
PYH2_k127_2279883_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 427.0
PYH2_k127_2353369_0 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 462.0
PYH2_k127_2353369_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000002746 224.0
PYH2_k127_2360351_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 4.952e-223 710.0
PYH2_k127_2360351_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 463.0
PYH2_k127_2360351_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 331.0
PYH2_k127_2360351_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000001142 141.0
PYH2_k127_2360351_4 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.00000000000000000000000004442 111.0
PYH2_k127_2360351_5 - - - - 0.000000000001425 70.0
PYH2_k127_2364313_0 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 504.0
PYH2_k127_2364313_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 486.0
PYH2_k127_2364313_2 - - - - 0.0000000000000000000000000000000000000000000000000000003331 201.0
PYH2_k127_237827_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.858e-194 621.0
PYH2_k127_237827_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000001335 212.0
PYH2_k127_2407688_0 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000001157 168.0
PYH2_k127_2407688_1 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000008235 150.0
PYH2_k127_2407688_2 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000001391 143.0
PYH2_k127_2407688_3 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000431 116.0
PYH2_k127_2425516_0 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 422.0
PYH2_k127_2425516_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 412.0
PYH2_k127_2425516_2 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
PYH2_k127_2425516_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
PYH2_k127_2425516_4 response to antibiotic K07122 - - 0.0000000000000005701 89.0
PYH2_k127_2425516_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000001687 67.0
PYH2_k127_2430551_0 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 467.0
PYH2_k127_2430551_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 448.0
PYH2_k127_2430551_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.00000000000000000000000395 112.0
PYH2_k127_2450929_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1052.0
PYH2_k127_2450929_1 Transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
PYH2_k127_2450929_2 Haem-degrading - - - 0.000000000000000000000000000000000003524 159.0
PYH2_k127_2450929_3 - - - - 0.0009133 46.0
PYH2_k127_2454547_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 610.0
PYH2_k127_2454547_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 468.0
PYH2_k127_2454547_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 477.0
PYH2_k127_2454547_3 integral membrane protein - - - 0.0000000000000000000002388 97.0
PYH2_k127_2454547_4 Predicted integral membrane protein (DUF2269) - - - 0.00000000004248 67.0
PYH2_k127_2454547_5 - - - - 0.0000000009836 61.0
PYH2_k127_2454547_7 integral membrane protein - - - 0.00002196 47.0
PYH2_k127_2455359_0 His Kinase A (phospho-acceptor) domain - - - 1.77e-281 875.0
PYH2_k127_2455359_1 - - - - 0.000000000000001895 78.0
PYH2_k127_2455359_2 Metallo-beta-lactamase superfamily - - - 0.000000003884 57.0
PYH2_k127_2461013_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1196.0
PYH2_k127_2461013_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000003219 75.0
PYH2_k127_2461013_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000001315 70.0
PYH2_k127_2466260_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1378.0
PYH2_k127_2466260_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000003729 250.0
PYH2_k127_2466260_2 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
PYH2_k127_2466260_3 Lipocalin-like domain - - - 0.000000000000000000000000000000000004978 138.0
PYH2_k127_2466260_4 - - - - 0.00000000000000000003934 94.0
PYH2_k127_2478650_0 acyl-CoA dehydrogenase K06445 - - 8.881e-290 902.0
PYH2_k127_248579_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
PYH2_k127_248579_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 350.0
PYH2_k127_248579_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000002253 255.0
PYH2_k127_248579_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000001354 203.0
PYH2_k127_248579_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000007245 85.0
PYH2_k127_2488344_0 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 623.0
PYH2_k127_2488344_1 S-layer homology domain - - - 0.0000000005245 74.0
PYH2_k127_249219_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 1.949e-195 617.0
PYH2_k127_249219_1 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
PYH2_k127_2500341_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 331.0
PYH2_k127_2500341_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000003564 169.0
PYH2_k127_2500341_2 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000001725 102.0
PYH2_k127_2505655_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 535.0
PYH2_k127_2505655_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 303.0
PYH2_k127_2505655_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006112 256.0
PYH2_k127_2515798_0 Male sterility - - - 5.132e-284 887.0
PYH2_k127_2515798_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 402.0
PYH2_k127_2515798_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000005204 138.0
PYH2_k127_2515798_3 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000003032 136.0
PYH2_k127_2531028_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 495.0
PYH2_k127_2531028_1 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.00000000000000000001027 94.0
PYH2_k127_2536843_0 extracellular solute-binding protein - - - 4.618e-227 716.0
PYH2_k127_2536843_1 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 598.0
PYH2_k127_2536843_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 429.0
PYH2_k127_2536843_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000002052 125.0
PYH2_k127_2536843_4 - - - - 0.00000000004237 65.0
PYH2_k127_2537771_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1254.0
PYH2_k127_2537771_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.9e-221 690.0
PYH2_k127_2537771_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 552.0
PYH2_k127_2537771_3 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 416.0
PYH2_k127_2537771_4 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 365.0
PYH2_k127_2537771_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 353.0
PYH2_k127_2537771_6 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000005997 250.0
PYH2_k127_2537771_7 - - - - 0.0005039 52.0
PYH2_k127_2549448_0 type I secretion membrane fusion K02022,K12537 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 335.0
PYH2_k127_2549448_1 Peptidase S8 K08651,K14645 - 3.4.21.66 0.0000000000000000000000000000000000000000000001428 175.0
PYH2_k127_2549448_2 Protein of unknown function (DUF3467) - - - 0.0002032 50.0
PYH2_k127_2570165_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 7.68e-268 829.0
PYH2_k127_2570165_1 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
PYH2_k127_2570165_2 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000007576 234.0
PYH2_k127_2570165_3 maturation - - - 0.0000000000000000000000000000000000000000000009241 171.0
PYH2_k127_2570165_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000947 165.0
PYH2_k127_2570165_5 Protein of unknown function (DUF504) - - - 0.00000000000000000003838 101.0
PYH2_k127_2591701_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002691 274.0
PYH2_k127_2591701_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
PYH2_k127_2591701_2 Protein of unknown function (DUF1761) - - - 0.00000001601 61.0
PYH2_k127_2606438_0 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
PYH2_k127_2606438_1 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 456.0
PYH2_k127_2606438_2 17 kDa surface antigen K06077 - - 0.000000000000614 72.0
PYH2_k127_2609167_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
PYH2_k127_2609167_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 398.0
PYH2_k127_2627572_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
PYH2_k127_2627572_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000008177 177.0
PYH2_k127_2627572_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000002177 68.0
PYH2_k127_2638837_0 Magnesium transport protein CorA - - - 3.854e-229 721.0
PYH2_k127_2638837_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
PYH2_k127_2638837_2 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000004653 171.0
PYH2_k127_2644275_0 CoA-binding domain protein K09181 - - 4.351e-253 794.0
PYH2_k127_2675909_0 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 311.0
PYH2_k127_2675909_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000005622 216.0
PYH2_k127_2686022_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1011.0
PYH2_k127_2686022_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 3.427e-194 617.0
PYH2_k127_2686022_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 513.0
PYH2_k127_2686022_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 454.0
PYH2_k127_2686022_4 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
PYH2_k127_2686022_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 419.0
PYH2_k127_2686022_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000001056 62.0
PYH2_k127_2686022_7 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0004131 46.0
PYH2_k127_2696780_0 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000759 276.0
PYH2_k127_2696780_1 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000001592 182.0
PYH2_k127_2696780_2 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000001039 156.0
PYH2_k127_2755556_0 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001486 273.0
PYH2_k127_2755556_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000007041 104.0
PYH2_k127_2767634_0 Transmembrane secretion effector - - - 1.269e-236 749.0
PYH2_k127_2767634_1 AsmA family K07289,K07290 - - 0.0000000000000000000000000000009598 129.0
PYH2_k127_2782108_0 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
PYH2_k127_2782108_1 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 407.0
PYH2_k127_2782108_2 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
PYH2_k127_2782108_3 Binding-protein-dependent transport system inner membrane component K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 319.0
PYH2_k127_2782108_4 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000004957 168.0
PYH2_k127_2782108_5 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396,K17950 - 4.4.1.15,4.4.1.25 0.0000000000000000000000000001672 116.0
PYH2_k127_2782108_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000001873 110.0
PYH2_k127_281152_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 374.0
PYH2_k127_281152_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000004212 242.0
PYH2_k127_2814456_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 412.0
PYH2_k127_2814456_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000002022 196.0
PYH2_k127_2814456_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000004873 162.0
PYH2_k127_2852151_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.461e-254 791.0
PYH2_k127_2852151_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 360.0
PYH2_k127_2852151_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000001892 52.0
PYH2_k127_2856680_0 ribonuclease, Rne Rng family K08301 - - 1.362e-234 739.0
PYH2_k127_2856680_1 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
PYH2_k127_2856680_2 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000007616 150.0
PYH2_k127_2856680_3 DUF167 K09131 - - 0.00000000000000000000000006413 110.0
PYH2_k127_2856680_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000703 42.0
PYH2_k127_2859025_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 471.0
PYH2_k127_2859025_1 membrane - - - 0.0000000000000000007776 99.0
PYH2_k127_287126_0 Belongs to the CarB family K01955 - 6.3.5.5 2.963e-299 925.0
PYH2_k127_287126_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008589 260.0
PYH2_k127_287126_2 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000002232 122.0
PYH2_k127_2881692_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 286.0
PYH2_k127_2881692_1 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000001406 191.0
PYH2_k127_2911478_0 Histidine kinase - - - 2.567e-234 744.0
PYH2_k127_2911478_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000186 199.0
PYH2_k127_2911478_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000705 196.0
PYH2_k127_2911478_3 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000003854 180.0
PYH2_k127_2911478_4 Putative zinc-finger - - - 0.000000000001084 72.0
PYH2_k127_2911478_5 - - - - 0.00000001124 63.0
PYH2_k127_2912808_0 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
PYH2_k127_2912808_1 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
PYH2_k127_2912808_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
PYH2_k127_2912808_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
PYH2_k127_2912808_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001763 131.0
PYH2_k127_2912808_5 - - - - 0.00000000000000226 78.0
PYH2_k127_2912941_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 303.0
PYH2_k127_2912941_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 269.0
PYH2_k127_2912941_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
PYH2_k127_2912941_3 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000003311 209.0
PYH2_k127_2912941_4 Rubredoxin - - - 0.000000000000000000000000009988 119.0
PYH2_k127_2928557_0 Bacterial type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 434.0
PYH2_k127_2928557_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000005825 128.0
PYH2_k127_2937647_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 355.0
PYH2_k127_2937647_1 Gaf domain K03832 - - 0.00000000000000005009 93.0
PYH2_k127_2939232_0 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
PYH2_k127_2939232_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000001637 235.0
PYH2_k127_294059_0 RNA polymerase sigma factor K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 412.0
PYH2_k127_294059_1 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000001338 185.0
PYH2_k127_2959887_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001355 269.0
PYH2_k127_2959887_1 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
PYH2_k127_2959887_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001089 254.0
PYH2_k127_2959887_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
PYH2_k127_2960430_0 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 328.0
PYH2_k127_2960430_1 response regulator K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
PYH2_k127_2960430_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000176 115.0
PYH2_k127_2967337_0 Multicopper oxidase - - - 1.479e-211 678.0
PYH2_k127_2967337_1 signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000003251 252.0
PYH2_k127_2967337_2 COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.000000000000000000000001371 108.0
PYH2_k127_2986864_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 452.0
PYH2_k127_2986864_1 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000004468 207.0
PYH2_k127_2986864_2 MaoC like domain - - - 0.00000000000000000000000000000000000000002176 171.0
PYH2_k127_3002506_0 Sodium:solute symporter family - - - 6.102e-284 889.0
PYH2_k127_3002506_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 455.0
PYH2_k127_3002506_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000005619 157.0
PYH2_k127_3002506_3 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000004616 135.0
PYH2_k127_3009035_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 4.437e-200 630.0
PYH2_k127_3009035_1 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 378.0
PYH2_k127_3009035_2 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000009585 195.0
PYH2_k127_3009035_3 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000005128 170.0
PYH2_k127_3020306_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.685e-250 782.0
PYH2_k127_3020306_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003896 279.0
PYH2_k127_3034812_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 495.0
PYH2_k127_3034812_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
PYH2_k127_3034812_2 Thioredoxin-like - - - 0.00000000000000000000000000007437 124.0
PYH2_k127_3034812_3 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000001444 101.0
PYH2_k127_3035226_0 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 346.0
PYH2_k127_3035226_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009957 263.0
PYH2_k127_3035226_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
PYH2_k127_3035226_3 Bacterial SH3 domain - - - 0.0000000000000000000003236 110.0
PYH2_k127_3035304_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.174e-306 946.0
PYH2_k127_3035304_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 466.0
PYH2_k127_3035304_2 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 341.0
PYH2_k127_3035558_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 608.0
PYH2_k127_3035558_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 582.0
PYH2_k127_3035558_2 FAD linked oxidases, C-terminal domain K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 472.0
PYH2_k127_3035558_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 465.0
PYH2_k127_3035558_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 421.0
PYH2_k127_3035558_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 335.0
PYH2_k127_3035558_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000005387 178.0
PYH2_k127_3067029_0 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009398 245.0
PYH2_k127_3067029_1 PFAM transcription elongation factor GreA GreB - - - 0.00000000000000000000000000000000000000000000007137 178.0
PYH2_k127_3067029_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000001019 100.0
PYH2_k127_3067029_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000005834 52.0
PYH2_k127_3095122_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 469.0
PYH2_k127_3095122_1 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000001882 129.0
PYH2_k127_3095122_2 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000007236 118.0
PYH2_k127_3111711_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 461.0
PYH2_k127_3111711_1 Involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 342.0
PYH2_k127_3126293_0 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 337.0
PYH2_k127_3126293_1 SpoIIAA-like - - - 0.0000000000000000000000000000000000000117 153.0
PYH2_k127_3126293_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000001595 58.0
PYH2_k127_3126345_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 1.537e-213 675.0
PYH2_k127_3126345_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000001725 144.0
PYH2_k127_3126345_3 Protein of unknown function (DUF3891) - - - 0.000000003525 66.0
PYH2_k127_3161968_0 Multicopper oxidase K22349 - 1.16.3.3 3.815e-208 667.0
PYH2_k127_3161968_1 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000001751 122.0
PYH2_k127_3171353_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000003212 111.0
PYH2_k127_3171353_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000007332 58.0
PYH2_k127_3180502_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 370.0
PYH2_k127_3180502_1 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000659 125.0
PYH2_k127_3183630_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1438.0
PYH2_k127_3183630_1 type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004664 256.0
PYH2_k127_3188644_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 9.904e-278 864.0
PYH2_k127_3197235_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.5e-323 997.0
PYH2_k127_3197235_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
PYH2_k127_3197235_2 Planctomycete cytochrome C - - - 0.0000000000000000000000000000001809 128.0
PYH2_k127_3197235_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000003154 72.0
PYH2_k127_3197235_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000004247 56.0
PYH2_k127_3200095_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003889 243.0
PYH2_k127_3200095_1 Helix-turn-helix K21498 - - 0.0000000000000000000000000001546 116.0
PYH2_k127_3200095_2 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000005334 115.0
PYH2_k127_3200834_0 cytochrome - - - 1.679e-254 795.0
PYH2_k127_3200834_1 4Fe-4S single cluster domain - - - 8.715e-226 703.0
PYH2_k127_3200834_2 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
PYH2_k127_3200834_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
PYH2_k127_3200834_4 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000901 190.0
PYH2_k127_3201340_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.028e-209 657.0
PYH2_k127_3201340_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 345.0
PYH2_k127_3201340_2 - - - - 0.0000000000000000000000000000000000008742 141.0
PYH2_k127_3201340_3 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000002506 129.0
PYH2_k127_3203689_0 PFAM FMN-binding domain protein K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 435.0
PYH2_k127_3203689_1 - - - - 0.0000000000000000000000000000000000000000000002661 175.0
PYH2_k127_3203689_2 - - - - 0.000000000000005965 81.0
PYH2_k127_3203689_3 TraB family K09973 - - 0.0001485 45.0
PYH2_k127_3210145_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.094e-218 685.0
PYH2_k127_3210145_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 498.0
PYH2_k127_3210145_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
PYH2_k127_3210145_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000005051 192.0
PYH2_k127_3210145_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000003929 57.0
PYH2_k127_3221245_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000006822 206.0
PYH2_k127_3228862_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 550.0
PYH2_k127_3228862_1 domain, Protein K15923 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
PYH2_k127_3228862_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 371.0
PYH2_k127_3228862_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 357.0
PYH2_k127_3236961_0 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
PYH2_k127_3236961_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000004977 211.0
PYH2_k127_3236961_2 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000002649 179.0
PYH2_k127_3236961_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000007935 138.0
PYH2_k127_3236961_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000002589 117.0
PYH2_k127_3236961_5 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000001272 81.0
PYH2_k127_3246502_0 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 270.0
PYH2_k127_3246502_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000006325 96.0
PYH2_k127_3270387_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.785e-213 669.0
PYH2_k127_3270387_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH2_k127_3270387_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000001364 189.0
PYH2_k127_3281042_0 Enoyl-(Acyl carrier protein) reductase K00059,K00076 - 1.1.1.100,1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 313.0
PYH2_k127_3281042_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
PYH2_k127_3281042_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002973 248.0
PYH2_k127_3281042_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000874 226.0
PYH2_k127_3281042_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000001446 154.0
PYH2_k127_3281042_5 Transglutaminase-like superfamily - - - 0.0000000000000000000009558 96.0
PYH2_k127_3281042_6 Redoxin - - - 0.000000000000000001357 88.0
PYH2_k127_3281042_7 Belongs to the 'phage' integrase family - - - 0.00000000004749 64.0
PYH2_k127_3292787_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
PYH2_k127_3292787_1 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000001509 228.0
PYH2_k127_3305151_0 Major facilitator superfamily MFS_1 K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 432.0
PYH2_k127_3305151_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
PYH2_k127_3307460_0 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 427.0
PYH2_k127_3307460_1 NosL K19342 - - 0.000000000000000000000000000000000000000000000000000000000000002193 234.0
PYH2_k127_3307460_2 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.000000000000000000000000000000000000000000000000000000000000004014 220.0
PYH2_k127_3307460_3 - - - - 0.0000000000000000000000000000000001416 139.0
PYH2_k127_3307460_4 - - - - 0.000000000000000000002895 96.0
PYH2_k127_3312932_0 Malic enzyme K00029 - 1.1.1.40 0.0 1077.0
PYH2_k127_3312932_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
PYH2_k127_3312932_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000004881 216.0
PYH2_k127_3312932_3 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000001331 153.0
PYH2_k127_3312932_4 - - - - 0.00000000000001998 80.0
PYH2_k127_3314900_0 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 312.0
PYH2_k127_3314900_1 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 296.0
PYH2_k127_3330683_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1289.0
PYH2_k127_3330683_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 571.0
PYH2_k127_3330683_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 544.0
PYH2_k127_3330683_3 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000001298 209.0
PYH2_k127_3330683_4 Belongs to the ompA family K03286 - - 0.00000000000002515 76.0
PYH2_k127_3333031_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 476.0
PYH2_k127_3374769_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.974e-211 665.0
PYH2_k127_3374769_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 338.0
PYH2_k127_3374769_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 293.0
PYH2_k127_3429313_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
PYH2_k127_3429313_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000003217 186.0
PYH2_k127_3429313_2 Soluble lytic murein K08309 - - 0.00000000000000000000000000000000000008148 143.0
PYH2_k127_3449741_0 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 356.0
PYH2_k127_3449741_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
PYH2_k127_3449741_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
PYH2_k127_3449741_3 Protein of unknown function DUF45 K07043 - - 0.0001095 54.0
PYH2_k127_3454802_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
PYH2_k127_3454802_1 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 287.0
PYH2_k127_3454802_2 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000001042 186.0
PYH2_k127_3454802_3 Signal Transduction Histidine Kinase - - - 0.0000000000003255 82.0
PYH2_k127_3481848_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 6.456e-212 666.0
PYH2_k127_3481848_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 453.0
PYH2_k127_3481848_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 373.0
PYH2_k127_3481848_3 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000119 107.0
PYH2_k127_3492770_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 458.0
PYH2_k127_3492770_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000002033 160.0
PYH2_k127_3492770_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000002024 141.0
PYH2_k127_3492770_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000004866 110.0
PYH2_k127_352529_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 415.0
PYH2_k127_352529_1 PIN domain - - - 0.000000000000000000000000000000000005473 145.0
PYH2_k127_353127_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1009.0
PYH2_k127_353127_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 395.0
PYH2_k127_3532023_0 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 334.0
PYH2_k127_3532023_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
PYH2_k127_3532023_2 Belongs to the DnaA family K10763 - - 0.000000000000001145 78.0
PYH2_k127_3533582_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 423.0
PYH2_k127_3533582_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000002971 196.0
PYH2_k127_3552540_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1e-323 1006.0
PYH2_k127_3552540_1 AAA ATPase central domain protein K07478 - - 7.741e-221 691.0
PYH2_k127_3552540_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.254e-209 657.0
PYH2_k127_3552540_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 523.0
PYH2_k127_3552540_4 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004113 236.0
PYH2_k127_3552540_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
PYH2_k127_3552540_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000803 226.0
PYH2_k127_3552540_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
PYH2_k127_3552540_8 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000008916 202.0
PYH2_k127_3552540_9 Small MutS-related domain - - - 0.00000000000000000000000000000000000000000000000000127 189.0
PYH2_k127_3577461_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 321.0
PYH2_k127_3577461_1 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000006307 144.0
PYH2_k127_3603955_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 497.0
PYH2_k127_3603955_1 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 351.0
PYH2_k127_3603955_2 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004964 242.0
PYH2_k127_3603955_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000003997 190.0
PYH2_k127_3684521_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 308.0
PYH2_k127_3684521_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
PYH2_k127_3700591_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 506.0
PYH2_k127_3700591_1 abc transporter K06158 - - 0.0000002405 54.0
PYH2_k127_371177_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 9.938e-219 685.0
PYH2_k127_371177_1 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 313.0
PYH2_k127_371177_2 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000007831 246.0
PYH2_k127_371177_3 - - - - 0.000000000000000000000000000000001189 136.0
PYH2_k127_3719197_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 481.0
PYH2_k127_3719197_1 phage integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 272.0
PYH2_k127_3722993_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1169.0
PYH2_k127_3722993_1 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 318.0
PYH2_k127_3722993_2 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 283.0
PYH2_k127_3742943_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 535.0
PYH2_k127_3742943_1 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000006449 188.0
PYH2_k127_3742943_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000958 164.0
PYH2_k127_3742943_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001434 132.0
PYH2_k127_3747702_0 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 502.0
PYH2_k127_3747702_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 348.0
PYH2_k127_3747702_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000000000000000000000000000000000004655 173.0
PYH2_k127_3747702_3 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000002533 86.0
PYH2_k127_377327_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 399.0
PYH2_k127_377327_1 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 329.0
PYH2_k127_3781968_0 Belongs to the GPI family K01810 - 5.3.1.9 7.263e-267 829.0
PYH2_k127_3781968_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000001318 97.0
PYH2_k127_3786750_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.103e-274 848.0
PYH2_k127_3786750_1 Cytochrome c oxidase, subunit K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 384.0
PYH2_k127_3786750_2 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 337.0
PYH2_k127_3786750_3 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000001559 79.0
PYH2_k127_3786750_4 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0000000000000003697 80.0
PYH2_k127_3786750_5 Cbb3-type cytochrome oxidase K00407 - - 0.00000000001071 69.0
PYH2_k127_3795017_0 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 366.0
PYH2_k127_3795017_1 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000003933 169.0
PYH2_k127_3797206_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1818.0
PYH2_k127_3797206_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000001984 109.0
PYH2_k127_3831081_0 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 367.0
PYH2_k127_3831081_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000006069 220.0
PYH2_k127_3853592_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 587.0
PYH2_k127_3853592_1 AraC family transcriptional regulator - - - 0.0000000000000000000000371 108.0
PYH2_k127_3861577_0 NADPH-dependent glutamate synthase beta - - - 3.999e-306 949.0
PYH2_k127_3861577_1 Fe-S oxidoreductase K21834 - - 2.162e-267 828.0
PYH2_k127_3861577_10 - - - - 0.000000000000000000000000004002 115.0
PYH2_k127_3861577_11 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000006535 94.0
PYH2_k127_3861577_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 501.0
PYH2_k127_3861577_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 353.0
PYH2_k127_3861577_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 354.0
PYH2_k127_3861577_5 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 346.0
PYH2_k127_3861577_6 sulfur relay protein TusD DsrE K07235 - - 0.0000000000000000000000000000000000000000000000000000000000008776 215.0
PYH2_k127_3861577_7 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000000001699 214.0
PYH2_k127_3861577_8 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000002056 201.0
PYH2_k127_3861577_9 DsrH like protein K07237 - - 0.000000000000000000000000000000388 125.0
PYH2_k127_3866341_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 566.0
PYH2_k127_3866341_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
PYH2_k127_3866341_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 333.0
PYH2_k127_3866341_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000007054 107.0
PYH2_k127_3874569_0 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 337.0
PYH2_k127_3874569_1 GAF domain - - - 0.000000000000000001691 91.0
PYH2_k127_388027_0 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
PYH2_k127_388027_1 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000009318 145.0
PYH2_k127_388027_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000009443 126.0
PYH2_k127_388027_3 Transcriptional regulator, MerR family - - - 0.0000000000000000000006034 100.0
PYH2_k127_388156_0 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
PYH2_k127_388156_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 237.0
PYH2_k127_388156_2 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000000000000007776 172.0
PYH2_k127_388156_3 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.0000000000000000000000000000000000000000005108 160.0
PYH2_k127_388156_4 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000003285 147.0
PYH2_k127_388156_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000002038 70.0
PYH2_k127_3901963_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 555.0
PYH2_k127_3901963_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 297.0
PYH2_k127_3903572_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
PYH2_k127_3903572_1 Protein of unknown function, DUF393 - - - 0.000611 46.0
PYH2_k127_3913969_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 375.0
PYH2_k127_3913969_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
PYH2_k127_3913969_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000001231 113.0
PYH2_k127_3962937_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 421.0
PYH2_k127_3962937_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 398.0
PYH2_k127_3962937_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
PYH2_k127_3962937_3 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000005075 250.0
PYH2_k127_3962937_4 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
PYH2_k127_3962937_5 NusG domain II - - - 0.00000000000004108 77.0
PYH2_k127_3991892_0 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
PYH2_k127_3991892_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003746 269.0
PYH2_k127_3991892_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000006006 222.0
PYH2_k127_4005852_0 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 484.0
PYH2_k127_4065323_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003038 259.0
PYH2_k127_4065323_1 Nuclease-related domain - - - 0.0000000000000000000000000000000000000000000000000000000001394 209.0
PYH2_k127_4065323_2 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000987 144.0
PYH2_k127_4073820_0 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
PYH2_k127_4073820_1 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000003272 172.0
PYH2_k127_4073820_2 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000001369 176.0
PYH2_k127_4073820_3 hemolysin activation secretion protein - - - 0.000000000000005292 79.0
PYH2_k127_4073820_4 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000001869 69.0
PYH2_k127_4078925_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 8.369e-209 658.0
PYH2_k127_4088869_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.915e-217 682.0
PYH2_k127_4088869_2 PFAM Cytochrome c assembly protein - - - 0.0000002247 53.0
PYH2_k127_4089085_0 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 506.0
PYH2_k127_4089085_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 461.0
PYH2_k127_4089085_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000931 74.0
PYH2_k127_4089784_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 381.0
PYH2_k127_4089784_1 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002325 236.0
PYH2_k127_4089784_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000538 126.0
PYH2_k127_4119356_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1177.0
PYH2_k127_4119356_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 1.464e-206 663.0
PYH2_k127_4133216_0 Lysin motif K08307 - - 3.111e-219 695.0
PYH2_k127_4133216_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000004791 198.0
PYH2_k127_4139813_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 482.0
PYH2_k127_4139813_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
PYH2_k127_4139813_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004998 282.0
PYH2_k127_4147005_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1067.0
PYH2_k127_4147005_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 302.0
PYH2_k127_4147005_2 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000004183 182.0
PYH2_k127_4147005_3 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000004284 175.0
PYH2_k127_4147005_4 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000001109 143.0
PYH2_k127_4147005_5 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000004627 139.0
PYH2_k127_4147005_6 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000000001849 126.0
PYH2_k127_4147005_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000005107 66.0
PYH2_k127_415888_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1230.0
PYH2_k127_415888_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 356.0
PYH2_k127_415888_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004905 256.0
PYH2_k127_415965_0 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 265.0
PYH2_k127_415965_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
PYH2_k127_415965_2 Glycine zipper 2TM domain - - - 0.00001716 49.0
PYH2_k127_4195135_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 354.0
PYH2_k127_4195135_1 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 325.0
PYH2_k127_4235407_0 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 434.0
PYH2_k127_426942_0 Poly-beta-hydroxybutyrate K03821 - - 6.723e-212 673.0
PYH2_k127_426942_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.66e-211 665.0
PYH2_k127_426942_2 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
PYH2_k127_426942_3 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002247 198.0
PYH2_k127_426942_4 PFAM CheW domain protein K02659 - - 0.000000000000000000000000000000000000000000004014 171.0
PYH2_k127_426942_5 COG0569 K transport systems, NAD-binding component K03499 - - 0.00000000000000000000000000000000205 131.0
PYH2_k127_4314178_0 GYD domain - - - 0.000000000000000000000000001555 116.0
PYH2_k127_4314178_1 cAMP biosynthetic process - - - 0.00000000000001579 78.0
PYH2_k127_4314178_2 - - - - 0.00006664 48.0
PYH2_k127_4326339_0 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 454.0
PYH2_k127_4326339_1 4Fe-4S binding domain K05524 - - 0.0000000000000000000000000000000000009139 142.0
PYH2_k127_4375961_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 8.038e-228 715.0
PYH2_k127_4375961_1 Type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 529.0
PYH2_k127_4375961_2 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000005323 207.0
PYH2_k127_4379967_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 554.0
PYH2_k127_4379967_1 - - - - 0.00000004287 59.0
PYH2_k127_4386517_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 498.0
PYH2_k127_4386517_1 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 346.0
PYH2_k127_4417462_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 492.0
PYH2_k127_4417462_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 297.0
PYH2_k127_4455534_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 574.0
PYH2_k127_4455534_1 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
PYH2_k127_4455534_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000171 149.0
PYH2_k127_4455534_3 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000002113 124.0
PYH2_k127_4455642_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 379.0
PYH2_k127_4455642_1 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 368.0
PYH2_k127_4455642_2 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
PYH2_k127_4455642_3 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000002672 55.0
PYH2_k127_4480581_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 6.723e-249 774.0
PYH2_k127_4480581_1 Acts as a magnesium transporter K06213 - - 1.906e-210 663.0
PYH2_k127_4480581_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 344.0
PYH2_k127_4480581_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000002418 151.0
PYH2_k127_4483108_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
PYH2_k127_4483108_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 445.0
PYH2_k127_4483108_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000001536 196.0
PYH2_k127_4483108_3 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000000000001326 125.0
PYH2_k127_450556_0 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 605.0
PYH2_k127_450556_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 480.0
PYH2_k127_450556_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 347.0
PYH2_k127_450556_3 PFAM NAD-dependent epimerase dehydratase K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000006627 71.0
PYH2_k127_451895_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 286.0
PYH2_k127_451895_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006193 182.0
PYH2_k127_451895_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000002702 59.0
PYH2_k127_4553297_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 1.764e-248 776.0
PYH2_k127_4553297_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.081e-220 689.0
PYH2_k127_4553297_2 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 334.0
PYH2_k127_4553297_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 285.0
PYH2_k127_4556373_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 362.0
PYH2_k127_4556373_1 - - - - 0.00000000000000000000000000000000000000008518 162.0
PYH2_k127_4556373_2 Pfam Fatty acid - - - 0.000000000000000000000001056 116.0
PYH2_k127_4556373_3 glycosyl transferase family - - - 0.00000000000005026 72.0
PYH2_k127_4567032_0 - K16704 - 2.3.1.210 0.00000000000000000000000000000000000006769 149.0
PYH2_k127_4567032_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000004971 138.0
PYH2_k127_4567032_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000001665 121.0
PYH2_k127_4580630_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 554.0
PYH2_k127_4580630_1 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
PYH2_k127_4580630_2 Dolichyl-phosphate-mannose-protein mannosyltransferase K00786 - - 0.0000000000000000000000000000000000000000000000000007538 192.0
PYH2_k127_4580630_3 GtrA-like protein - - - 0.000000000000000000000000178 112.0
PYH2_k127_4583303_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 9.644e-225 709.0
PYH2_k127_4583303_1 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
PYH2_k127_4583303_2 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
PYH2_k127_4583303_3 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000007464 112.0
PYH2_k127_4583303_4 - - - - 0.0003668 48.0
PYH2_k127_4611372_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 6.941e-241 756.0
PYH2_k127_4611372_1 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 436.0
PYH2_k127_4611372_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000003767 169.0
PYH2_k127_4630033_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 589.0
PYH2_k127_4630033_1 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
PYH2_k127_4630033_2 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
PYH2_k127_4630033_3 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000000000000000000000000000000000000006405 154.0
PYH2_k127_4630033_4 PaaD-like protein - - - 0.00000000000000000000000000000000000002592 146.0
PYH2_k127_4651467_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 470.0
PYH2_k127_4651467_1 - - - - 0.000000000000000000000000000000003408 133.0
PYH2_k127_465378_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.265e-253 788.0
PYH2_k127_4714838_0 elongation factor G K02355 - - 5e-324 1005.0
PYH2_k127_4714838_1 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
PYH2_k127_4714838_2 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
PYH2_k127_4714838_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000008404 145.0
PYH2_k127_4714838_4 - - - - 0.00000000000000000000000000000001337 128.0
PYH2_k127_4714838_5 Lipase maturation factor - - - 0.0000000000003039 74.0
PYH2_k127_472895_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 464.0
PYH2_k127_472895_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
PYH2_k127_472895_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000002912 89.0
PYH2_k127_4780651_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1389.0
PYH2_k127_4780651_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.00000000000000000000003734 105.0
PYH2_k127_4809900_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1035.0
PYH2_k127_4809900_1 TonB-dependent Receptor Plug K02014 - - 5.511e-252 798.0
PYH2_k127_4809900_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 534.0
PYH2_k127_4809900_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 302.0
PYH2_k127_4809900_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
PYH2_k127_4809900_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
PYH2_k127_4809900_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000002981 108.0
PYH2_k127_4809900_7 Mut7-C ubiquitin - - - 0.00000000000000000000001721 113.0
PYH2_k127_4830158_0 PFAM ABC-1 domain protein K03688 - - 2.384e-248 777.0
PYH2_k127_4830158_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 2.599e-248 780.0
PYH2_k127_4830158_2 - - - - 0.000000000000000000000000000000000000000000000000000005079 197.0
PYH2_k127_4830158_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000007796 182.0
PYH2_k127_4830158_4 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.0000000000000001203 93.0
PYH2_k127_4842663_0 FeS assembly protein SufB K09014 - - 1.013e-220 690.0
PYH2_k127_4842663_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
PYH2_k127_4842663_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001036 173.0
PYH2_k127_4842663_3 Domain of unknown function (DUF1992) - - - 0.00000000000000000001326 104.0
PYH2_k127_4850989_0 FAD binding domain K00394 - 1.8.99.2 0.0 1238.0
PYH2_k127_4850989_1 PFAM AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
PYH2_k127_4850989_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 385.0
PYH2_k127_4871869_0 membrane protein involved in D-alanine export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 513.0
PYH2_k127_4871869_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 507.0
PYH2_k127_4871869_2 - - - - 0.0000000000000000000000000000000000000000000001194 192.0
PYH2_k127_4871869_3 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000006949 182.0
PYH2_k127_4871869_4 polysaccharide deacetylase - - - 0.000000000000000000001247 105.0
PYH2_k127_4882257_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 449.0
PYH2_k127_4882257_1 PFAM LemA family K03744 - - 0.00000000000000000000000000008307 117.0
PYH2_k127_4900048_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
PYH2_k127_4900048_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000001746 209.0
PYH2_k127_4900048_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
PYH2_k127_49079_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.237e-224 699.0
PYH2_k127_49079_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000001963 124.0
PYH2_k127_492714_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1410.0
PYH2_k127_5003154_0 GMP synthase C terminal domain K01951 - 6.3.5.2 1.485e-299 923.0
PYH2_k127_5003154_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.992e-249 776.0
PYH2_k127_5003154_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000001149 148.0
PYH2_k127_5003154_3 Domain of unknown function (DUF4124) - - - 0.0000000000000007687 85.0
PYH2_k127_5003954_0 SNARE associated Golgi protein - - - 0.0 1042.0
PYH2_k127_5003954_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 561.0
PYH2_k127_5003954_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 430.0
PYH2_k127_5003954_3 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 326.0
PYH2_k127_5003954_4 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000001313 137.0
PYH2_k127_5015579_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.002e-206 649.0
PYH2_k127_5015579_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000002564 190.0
PYH2_k127_5015579_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000007438 172.0
PYH2_k127_5015579_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000011 142.0
PYH2_k127_5026147_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 610.0
PYH2_k127_5026147_1 PFAM multicopper oxidase type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 578.0
PYH2_k127_5026147_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000002934 174.0
PYH2_k127_5026147_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000002184 169.0
PYH2_k127_5065281_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 435.0
PYH2_k127_5065281_1 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
PYH2_k127_5065281_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
PYH2_k127_5079913_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 499.0
PYH2_k127_5079913_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 325.0
PYH2_k127_5079913_2 metal cluster binding - - - 0.000000000000000000000000000003496 130.0
PYH2_k127_5090359_0 alpha beta hydrolase fold K03821 - - 7.498e-246 771.0
PYH2_k127_5090359_1 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 540.0
PYH2_k127_5090359_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 460.0
PYH2_k127_5090359_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 321.0
PYH2_k127_5090359_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000003557 229.0
PYH2_k127_5090359_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000001022 162.0
PYH2_k127_5090359_6 Putative regulatory protein - - - 0.00000000000000000000000000001192 121.0
PYH2_k127_5090359_7 Type II secretion system protein B K02451 - - 0.0000000000000000009633 89.0
PYH2_k127_5099282_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 572.0
PYH2_k127_5099282_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
PYH2_k127_5099282_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 395.0
PYH2_k127_5099282_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
PYH2_k127_5099282_4 type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
PYH2_k127_5099282_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000003111 207.0
PYH2_k127_5099282_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000008888 116.0
PYH2_k127_5115576_0 Large family of predicted nucleotide-binding domains K07175 - - 3.918e-254 789.0
PYH2_k127_5115576_1 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007663 256.0
PYH2_k127_5115576_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000004431 208.0
PYH2_k127_5121225_0 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 454.0
PYH2_k127_5121225_1 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001152 242.0
PYH2_k127_5121225_2 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000002808 163.0
PYH2_k127_5121225_3 - - - - 0.0000000000000000000000000000000000000007986 154.0
PYH2_k127_5123037_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1759.0
PYH2_k127_5123037_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
PYH2_k127_5125611_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 6.239e-212 660.0
PYH2_k127_5125611_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.042e-211 665.0
PYH2_k127_5125611_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 575.0
PYH2_k127_5125611_3 Fe-S cluster K03616 - - 0.000000000000000000000000000000003575 135.0
PYH2_k127_5125611_4 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000002936 121.0
PYH2_k127_5125611_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000005877 89.0
PYH2_k127_5144509_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.003e-214 672.0
PYH2_k127_5144509_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 474.0
PYH2_k127_5144509_2 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 471.0
PYH2_k127_5144509_3 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 315.0
PYH2_k127_5144509_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000002298 175.0
PYH2_k127_5144509_5 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000007192 150.0
PYH2_k127_5144509_6 - - - - 0.000000000000001358 83.0
PYH2_k127_5144509_7 Recombinase zinc beta ribbon domain K06400 - - 0.000000003532 62.0
PYH2_k127_5158996_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.94e-270 844.0
PYH2_k127_5270083_0 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 463.0
PYH2_k127_5270083_1 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000027 234.0
PYH2_k127_5270083_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000003999 70.0
PYH2_k127_5270083_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000005028 68.0
PYH2_k127_5278175_0 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 325.0
PYH2_k127_5278175_1 Histidine kinase K07637 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
PYH2_k127_5278175_2 - - - - 0.0000000001827 63.0
PYH2_k127_5310630_0 Tail sheath protein K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 604.0
PYH2_k127_5310630_1 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000000000001192 189.0
PYH2_k127_5344645_0 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 287.0
PYH2_k127_5344645_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001503 279.0
PYH2_k127_5344645_2 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000003504 184.0
PYH2_k127_5392696_0 Multicopper oxidase K22349 - 1.16.3.3 1.856e-214 677.0
PYH2_k127_5429400_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000004452 247.0
PYH2_k127_5429400_1 - - - - 0.00000000000000001147 97.0
PYH2_k127_5429400_2 - - - - 0.0000000000000002644 89.0
PYH2_k127_5434070_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
PYH2_k127_5434070_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
PYH2_k127_5486013_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
PYH2_k127_5486013_1 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000003891 151.0
PYH2_k127_5486013_2 SpoIIAA-like - - - 0.00000000000000000000000000000000002158 138.0
PYH2_k127_5505691_0 PQQ-like domain K00114 - 1.1.2.8 1.172e-316 979.0
PYH2_k127_5505691_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
PYH2_k127_5505691_2 Sulphur oxidation protein SoxZ K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 299.0
PYH2_k127_5505691_3 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 298.0
PYH2_k127_5505691_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003327 269.0
PYH2_k127_5505691_5 - - - - 0.0000000000000001333 83.0
PYH2_k127_5505691_6 - - - - 0.00000000001767 74.0
PYH2_k127_5521278_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 9.192e-312 970.0
PYH2_k127_5521278_1 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 453.0
PYH2_k127_5521278_2 PFAM AFG1-family ATPase K06916 - - 0.000000000000000000000000000000000000009332 146.0
PYH2_k127_5521278_3 blue (type 1) copper - - - 0.00000000000479 67.0
PYH2_k127_5532418_0 Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 597.0
PYH2_k127_5532418_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 473.0
PYH2_k127_5532418_2 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
PYH2_k127_5532418_3 FecR protein - - - 0.000000000000000000000000000001397 133.0
PYH2_k127_5532418_4 FAD binding domain - - - 0.0000000000000000000002368 98.0
PYH2_k127_5532418_5 Protein of unknown function (DUF560) - - - 0.00000000000001125 87.0
PYH2_k127_5553731_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 554.0
PYH2_k127_5565291_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1015.0
PYH2_k127_5567676_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1242.0
PYH2_k127_5567676_1 - - - - 0.000000000000000000000002052 112.0
PYH2_k127_5573148_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 437.0
PYH2_k127_5573148_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 316.0
PYH2_k127_5573148_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH2_k127_5573148_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
PYH2_k127_5573148_4 - - - - 0.000000000000000000000000000000000000000000000003008 182.0
PYH2_k127_5573148_5 regulation of methylation-dependent chromatin silencing K03684,K09968 - 3.1.13.5 0.0000000000000000000000000000000000000001795 154.0
PYH2_k127_5573148_7 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000008739 86.0
PYH2_k127_5582586_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 342.0
PYH2_k127_5582586_1 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
PYH2_k127_5582586_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000003912 232.0
PYH2_k127_5598926_0 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 438.0
PYH2_k127_5598926_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.0000000000000000000000000000004215 126.0
PYH2_k127_5598926_2 Protein of unknown function (DUF1289) K06938 - - 0.0000000001636 63.0
PYH2_k127_561657_0 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 443.0
PYH2_k127_561657_1 ABC transporter transmembrane region K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000001356 235.0
PYH2_k127_561657_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000007289 147.0
PYH2_k127_561657_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000007467 102.0
PYH2_k127_561657_4 positive regulation of growth K07746 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000457 55.0
PYH2_k127_5634373_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.998e-250 780.0
PYH2_k127_5634373_1 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000001737 55.0
PYH2_k127_5684918_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.759e-198 626.0
PYH2_k127_5684918_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
PYH2_k127_5684918_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 352.0
PYH2_k127_5684918_3 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000002145 126.0
PYH2_k127_5684918_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000004549 63.0
PYH2_k127_5684918_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000001187 57.0
PYH2_k127_5702750_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 527.0
PYH2_k127_5702750_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 346.0
PYH2_k127_5702750_2 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000757 147.0
PYH2_k127_5702750_3 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000146 137.0
PYH2_k127_5702750_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000001597 131.0
PYH2_k127_5790189_0 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 427.0
PYH2_k127_5790189_1 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000001041 185.0
PYH2_k127_5791691_0 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 420.0
PYH2_k127_5791691_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 317.0
PYH2_k127_5791691_2 LUD domain K00782 - - 0.000000000000000000000000000000000000000001268 157.0
PYH2_k127_5800848_0 FAD linked oxidases, C-terminal domain K18930 - - 1.585e-310 964.0
PYH2_k127_5800848_1 haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000002891 74.0
PYH2_k127_5801221_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.719e-259 806.0
PYH2_k127_5801221_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 473.0
PYH2_k127_5801221_2 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 314.0
PYH2_k127_5801221_3 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 308.0
PYH2_k127_5801221_4 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
PYH2_k127_5834003_0 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001223 249.0
PYH2_k127_5834003_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006263 246.0
PYH2_k127_5834003_2 TIGRFAM daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000002954 189.0
PYH2_k127_5834003_3 Transport permease protein K01992 - - 0.000000000181 74.0
PYH2_k127_5839989_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1371.0
PYH2_k127_5839989_1 UvrD REP K03657 - 3.6.4.12 0.0 1011.0
PYH2_k127_5839989_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 480.0
PYH2_k127_5839989_3 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 407.0
PYH2_k127_5839989_4 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 391.0
PYH2_k127_5839989_5 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000006542 147.0
PYH2_k127_5839989_6 - - - - 0.00000000000000003702 84.0
PYH2_k127_5840132_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 312.0
PYH2_k127_5840132_1 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003606 181.0
PYH2_k127_5840132_2 transcriptional regulator - - - 0.000000000000000000000000000000007199 129.0
PYH2_k127_5840132_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000754 119.0
PYH2_k127_5873379_0 PFAM Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 362.0
PYH2_k127_5873379_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000002679 163.0
PYH2_k127_5873379_2 - - - - 0.0000000001057 66.0
PYH2_k127_588696_0 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 409.0
PYH2_k127_588696_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 368.0
PYH2_k127_588696_2 membrane protein domain - - - 0.00000000002265 64.0
PYH2_k127_588696_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000004846 59.0
PYH2_k127_589264_0 Protein of unknown function (DUF3141) - - - 0.0 1032.0
PYH2_k127_589264_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 539.0
PYH2_k127_589264_2 phosphate K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
PYH2_k127_589264_3 - - - - 0.00000000000000002774 87.0
PYH2_k127_589264_4 - - - - 0.000000002987 63.0
PYH2_k127_5902942_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 522.0
PYH2_k127_5902942_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 531.0
PYH2_k127_5902942_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 359.0
PYH2_k127_5902942_3 PIN domain K07065 - - 0.0000000000000000000000000000000001078 137.0
PYH2_k127_5902942_4 Glycosyl transferases group 1 K03208 - - 0.000000000000001053 79.0
PYH2_k127_5937961_0 Multicopper oxidase K22349 - 1.16.3.3 1e-322 1006.0
PYH2_k127_5944928_0 B12 binding domain K00548 - 2.1.1.13 0.0 1718.0
PYH2_k127_5944928_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 420.0
PYH2_k127_5944928_2 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
PYH2_k127_5944928_3 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000008635 98.0
PYH2_k127_5952980_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008347 253.0
PYH2_k127_5952980_1 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000005049 240.0
PYH2_k127_5952980_2 - - - - 0.000000000000003165 84.0
PYH2_k127_5961608_0 argininosuccinate lyase K01755 - 4.3.2.1 5.391e-222 696.0
PYH2_k127_5961608_1 Histidine kinase K08082 - 2.7.13.3 0.0000000004356 64.0
PYH2_k127_5972963_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 8.038e-269 836.0
PYH2_k127_5972963_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 553.0
PYH2_k127_5972963_2 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000004204 109.0
PYH2_k127_599164_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1013.0
PYH2_k127_6013752_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.249e-290 897.0
PYH2_k127_6013752_1 SMART CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 589.0
PYH2_k127_6013752_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000007351 169.0
PYH2_k127_6013752_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000001638 148.0
PYH2_k127_6128233_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 445.0
PYH2_k127_6128233_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 306.0
PYH2_k127_6128233_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005469 230.0
PYH2_k127_6128233_3 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000008334 147.0
PYH2_k127_6131174_0 Response regulator receiver K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 598.0
PYH2_k127_6131174_1 PFAM Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 536.0
PYH2_k127_6131174_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002447 106.0
PYH2_k127_6131174_3 Sel1-like repeats. K07126 - - 0.000000000000001363 86.0
PYH2_k127_613517_0 protein synthesis factor, GTP-binding K06207 - - 4.782e-307 949.0
PYH2_k127_6164605_0 GGDEF domain - - - 8.777e-201 640.0
PYH2_k127_6179913_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 436.0
PYH2_k127_6179913_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 366.0
PYH2_k127_6179913_2 TPM domain K08988 - - 0.000000000000000000000000000000000001255 139.0
PYH2_k127_6186877_0 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
PYH2_k127_6186877_1 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
PYH2_k127_6186877_2 Part of a membrane complex involved in electron transport K03615 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - 0.00000000000001229 83.0
PYH2_k127_6195567_0 Belongs to the glycosyl hydrolase 57 family - - - 5.834e-241 756.0
PYH2_k127_6195567_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000005474 227.0
PYH2_k127_6214694_0 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 302.0
PYH2_k127_6214694_1 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000003832 209.0
PYH2_k127_6214694_2 - - - - 0.0000000000000000000000000000000000007502 153.0
PYH2_k127_6214694_3 - - - - 0.00000000000000000000000000001799 121.0
PYH2_k127_622456_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1023.0
PYH2_k127_622456_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.14e-204 648.0
PYH2_k127_622456_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
PYH2_k127_622456_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000002567 217.0
PYH2_k127_622456_4 Domain of unknown function (DUF4845) - - - 0.000000000000000000003672 100.0
PYH2_k127_622456_5 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.000000000000000000004211 96.0
PYH2_k127_6240682_0 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000000001436 136.0
PYH2_k127_6240682_1 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000002113 132.0
PYH2_k127_6240682_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000004395 86.0
PYH2_k127_6299815_0 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 607.0
PYH2_k127_6299815_1 cystathionine K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.00000000006934 64.0
PYH2_k127_6311585_0 PFAM Cys Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 494.0
PYH2_k127_6311585_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 431.0
PYH2_k127_6311585_2 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000001067 178.0
PYH2_k127_6311585_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002079 157.0
PYH2_k127_6312906_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.483e-261 812.0
PYH2_k127_6312906_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 409.0
PYH2_k127_6312906_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
PYH2_k127_6312906_3 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000442 127.0
PYH2_k127_6312906_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000002041 78.0
PYH2_k127_6332945_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 573.0
PYH2_k127_6332945_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 432.0
PYH2_k127_6359202_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 518.0
PYH2_k127_6359202_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 443.0
PYH2_k127_6359202_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 350.0
PYH2_k127_6359202_3 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 332.0
PYH2_k127_6382266_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.017e-210 663.0
PYH2_k127_6382266_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000009772 220.0
PYH2_k127_6382266_2 glycolate oxidase subunit GlcD - - - 0.00000000000000000000000000000000000000000000000000000000000001988 216.0
PYH2_k127_6382266_3 - - - - 0.0000000005811 60.0
PYH2_k127_6421666_0 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
PYH2_k127_6421666_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 245.0
PYH2_k127_6421666_2 TIGRFAM phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000003863 124.0
PYH2_k127_6421666_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000005392 77.0
PYH2_k127_6432650_0 chain 5 L K00341 - 1.6.5.3 9.971e-300 933.0
PYH2_k127_6432650_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 507.0
PYH2_k127_6432650_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 301.0
PYH2_k127_6432650_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004359 272.0
PYH2_k127_6432650_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000003088 171.0
PYH2_k127_6432650_5 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000001481 60.0
PYH2_k127_6432650_6 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.0005621 42.0
PYH2_k127_6447107_0 Transport Permease Protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008819 284.0
PYH2_k127_6447107_1 Amidohydrolase - - - 0.000000000000000000000000000000000000009401 151.0
PYH2_k127_6447107_2 Phasin protein - - - 0.000000000000000000000000000000000002402 145.0
PYH2_k127_6447107_3 pfam abc K01990 - - 0.00002443 47.0
PYH2_k127_646594_0 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000009695 156.0
PYH2_k127_649500_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 426.0
PYH2_k127_649500_1 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 307.0
PYH2_k127_649500_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000003673 204.0
PYH2_k127_649500_3 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000002402 155.0
PYH2_k127_649715_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 483.0
PYH2_k127_649715_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001928 265.0
PYH2_k127_6505768_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 2.257e-226 723.0
PYH2_k127_6505768_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 585.0
PYH2_k127_6505768_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
PYH2_k127_6505768_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 408.0
PYH2_k127_6505768_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 330.0
PYH2_k127_6505768_5 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000244 251.0
PYH2_k127_6505768_6 Protein of unknown function (DUF1318) K09978 - - 0.0000000000000000000000000000000000000000000000000000004231 196.0
PYH2_k127_6505768_7 Resolvase, N terminal domain - - - 0.000000001134 65.0
PYH2_k127_6505768_8 - - - - 0.000000003351 58.0
PYH2_k127_652205_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.887e-250 779.0
PYH2_k127_652205_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 560.0
PYH2_k127_652205_2 Protein of unknown function (DUF465) - - - 0.0000000000000005323 81.0
PYH2_k127_6537733_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.601e-196 616.0
PYH2_k127_6537733_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 514.0
PYH2_k127_6537733_2 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000244 205.0
PYH2_k127_6542021_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 588.0
PYH2_k127_6542021_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 355.0
PYH2_k127_6542021_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
PYH2_k127_6542021_3 - - - - 0.00000007274 57.0
PYH2_k127_6565029_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
PYH2_k127_6565029_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001136 269.0
PYH2_k127_6565029_2 Lytic murein transglycosylase B K08305 - - 0.000000000000000002655 86.0
PYH2_k127_657619_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 6.723e-205 649.0
PYH2_k127_657619_1 Biotin-lipoyl like K07799 - - 0.0006651 42.0
PYH2_k127_6642795_0 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.664e-201 632.0
PYH2_k127_6642795_1 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000002086 115.0
PYH2_k127_6709290_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 4.686e-319 989.0
PYH2_k127_6709290_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
PYH2_k127_6709290_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 323.0
PYH2_k127_6709290_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
PYH2_k127_6709290_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000004456 77.0
PYH2_k127_6718711_0 Multicopper oxidase K22349 - 1.16.3.3 3.016e-303 945.0
PYH2_k127_6721134_0 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 421.0
PYH2_k127_6721134_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 377.0
PYH2_k127_6725351_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.112e-215 684.0
PYH2_k127_6725351_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000001272 206.0
PYH2_k127_6725351_2 PFAM Cytochrome C - - - 0.0000000000000000000000001178 108.0
PYH2_k127_6784208_0 O-acetylhomoserine K01740 - 2.5.1.49 1.688e-227 709.0
PYH2_k127_6784208_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 292.0
PYH2_k127_6814384_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1052.0
PYH2_k127_6814384_1 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000009103 163.0
PYH2_k127_6814384_2 Thermostable hemolysin - - - 0.0000000000000000000000000000003408 128.0
PYH2_k127_6851766_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 565.0
PYH2_k127_6851766_1 - - - - 0.00000000000000000000000000000000000000000000000000004623 190.0
PYH2_k127_6864136_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 486.0
PYH2_k127_6864136_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 419.0
PYH2_k127_6864136_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006707 280.0
PYH2_k127_6864136_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000824 126.0
PYH2_k127_688446_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 1.082e-290 902.0
PYH2_k127_6886488_0 ABC transporter - - - 3.312e-292 904.0
PYH2_k127_6886488_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.407e-265 832.0
PYH2_k127_6886488_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
PYH2_k127_6886488_3 protein conserved in bacteria - - - 0.0000000000000000000000000002291 121.0
PYH2_k127_6886488_4 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000001257 115.0
PYH2_k127_6886488_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000002592 100.0
PYH2_k127_6937573_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 472.0
PYH2_k127_6944901_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 1.879e-285 885.0
PYH2_k127_6945470_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1385.0
PYH2_k127_6945470_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 542.0
PYH2_k127_6981253_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 476.0
PYH2_k127_6981253_1 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 290.0
PYH2_k127_7029414_0 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 542.0
PYH2_k127_7029414_1 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000001169 131.0
PYH2_k127_7029414_2 Protein of unknown function (DUF3460) - - - 0.0000000000003698 73.0
PYH2_k127_7058350_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1120.0
PYH2_k127_7058350_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.322e-215 674.0
PYH2_k127_7058350_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 7.225e-194 611.0
PYH2_k127_7058350_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 561.0
PYH2_k127_7058350_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
PYH2_k127_7058350_5 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005222 244.0
PYH2_k127_7058350_6 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000003263 188.0
PYH2_k127_7058350_7 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000008477 111.0
PYH2_k127_7067740_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 5.867e-230 719.0
PYH2_k127_7067740_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
PYH2_k127_7067740_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000006889 81.0
PYH2_k127_7103572_0 ABC transporter transmembrane region K06147 - - 2.927e-303 938.0
PYH2_k127_7103572_1 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
PYH2_k127_7103572_2 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 307.0
PYH2_k127_7103572_3 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000001918 236.0
PYH2_k127_7103572_4 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000003723 192.0
PYH2_k127_7103572_5 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000006976 194.0
PYH2_k127_7124993_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 486.0
PYH2_k127_7124993_1 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 308.0
PYH2_k127_7124993_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003791 280.0
PYH2_k127_7125511_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
PYH2_k127_7125511_1 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000004979 121.0
PYH2_k127_7125511_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000008635 71.0
PYH2_k127_7180668_0 Histidine kinase K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000004266 207.0
PYH2_k127_7180668_1 - - - - 0.000000000000000000000000000000000000001927 155.0
PYH2_k127_7180668_2 Phospholipid methyltransferase - - - 0.0000000000000000000185 93.0
PYH2_k127_718205_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 4.682e-212 662.0
PYH2_k127_718205_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 340.0
PYH2_k127_718205_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
PYH2_k127_718205_3 transcriptional - - - 0.0000000000000000000000000000000000000000187 157.0
PYH2_k127_718205_4 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000008862 55.0
PYH2_k127_7234140_0 Plasmid encoded RepA protein - - - 0.000000000000000000000000000000000000000000005516 171.0
PYH2_k127_7234140_1 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000000000000000001267 115.0
PYH2_k127_7237332_0 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 443.0
PYH2_k127_7237332_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 300.0
PYH2_k127_7249707_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 565.0
PYH2_k127_7249707_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
PYH2_k127_7249707_2 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 370.0
PYH2_k127_7249707_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000004924 251.0
PYH2_k127_725655_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 584.0
PYH2_k127_725655_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
PYH2_k127_725655_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 311.0
PYH2_k127_7290709_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000003772 155.0
PYH2_k127_7290709_1 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000001744 154.0
PYH2_k127_7290709_2 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.0000000009505 67.0
PYH2_k127_7320513_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
PYH2_k127_7320513_1 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000002064 123.0
PYH2_k127_7320513_2 PFAM TOBE domain protein - - - 0.000000000000000001779 87.0
PYH2_k127_7334673_0 Translation-initiation factor 2 K02519 - - 3.853e-297 922.0
PYH2_k127_7334673_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000003264 107.0
PYH2_k127_7336914_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 6.888e-247 767.0
PYH2_k127_7336914_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000178 151.0
PYH2_k127_7357423_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.14e-294 913.0
PYH2_k127_7368992_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 461.0
PYH2_k127_7368992_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000003457 181.0
PYH2_k127_7386017_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.252e-252 785.0
PYH2_k127_7386017_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 315.0
PYH2_k127_7386017_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000005773 214.0
PYH2_k127_7388449_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 575.0
PYH2_k127_7388449_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 515.0
PYH2_k127_7388449_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
PYH2_k127_7388449_3 PIN domain - - - 0.0000000000000000000000000000000000000000000003296 170.0
PYH2_k127_7388449_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000003339 155.0
PYH2_k127_7388449_5 positive regulation of growth K01081 - 3.1.3.5 0.00000000000000000000000001165 110.0
PYH2_k127_7388449_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000103 106.0
PYH2_k127_7415898_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 6.314e-267 830.0
PYH2_k127_7415898_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000001526 95.0
PYH2_k127_7426886_0 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 418.0
PYH2_k127_7426886_1 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 342.0
PYH2_k127_7426886_2 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 318.0
PYH2_k127_7426886_3 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000182 139.0
PYH2_k127_7432043_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 608.0
PYH2_k127_7432043_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000946 229.0
PYH2_k127_7474676_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
PYH2_k127_7474676_1 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000005964 213.0
PYH2_k127_7474676_2 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.00000000000001935 74.0
PYH2_k127_7475453_0 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
PYH2_k127_7475453_1 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000009769 133.0
PYH2_k127_7475453_2 Rubredoxin - - - 0.00000000000000000000002218 109.0
PYH2_k127_7475453_3 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000000000003576 77.0
PYH2_k127_7478389_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003623 290.0
PYH2_k127_7478389_1 COG3267 Type II secretory pathway, component ExeA - - - 0.000000000000000000000000000000000000000000000000002183 192.0
PYH2_k127_7481944_0 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 325.0
PYH2_k127_7481944_1 diguanylate cyclase - - - 0.0000000000000000000000000002931 119.0
PYH2_k127_7509455_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 366.0
PYH2_k127_7509455_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 326.0
PYH2_k127_7509455_2 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.0000000000000000000000000000000000001914 149.0
PYH2_k127_7511153_0 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 606.0
PYH2_k127_7511153_1 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
PYH2_k127_7511153_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
PYH2_k127_7511153_3 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000001524 241.0
PYH2_k127_7511153_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00002798 48.0
PYH2_k127_7521195_0 Pfam Fatty acid - - - 6.651e-306 950.0
PYH2_k127_7521195_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 426.0
PYH2_k127_7521195_2 Bile acid K03453 - - 0.000000002064 63.0
PYH2_k127_7536213_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.196e-255 798.0
PYH2_k127_7536213_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000006179 111.0
PYH2_k127_7536213_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000002799 73.0
PYH2_k127_7571663_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1190.0
PYH2_k127_7571663_1 Protein of unknown function (DUF2934) - - - 0.000001373 50.0
PYH2_k127_7626639_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 467.0
PYH2_k127_7626639_1 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 260.0
PYH2_k127_7626639_2 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000001429 161.0
PYH2_k127_7651381_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1328.0
PYH2_k127_7651381_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000945 114.0
PYH2_k127_7655941_0 Homospermidine synthase K00808 - 2.5.1.44 1.624e-217 687.0
PYH2_k127_7655941_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000007422 180.0
PYH2_k127_7655941_2 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000006477 100.0
PYH2_k127_7655941_3 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000005648 77.0
PYH2_k127_7655941_4 Protein of unknown function (DUF3567) - - - 0.00000000001197 68.0
PYH2_k127_7665874_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 595.0
PYH2_k127_7665874_1 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000006344 98.0
PYH2_k127_7665874_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000005678 98.0
PYH2_k127_767083_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1154.0
PYH2_k127_767083_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 1.707e-220 733.0
PYH2_k127_767083_2 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 391.0
PYH2_k127_767083_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 389.0
PYH2_k127_767083_4 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000002056 181.0
PYH2_k127_767083_5 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000004558 110.0
PYH2_k127_7689834_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 582.0
PYH2_k127_7689834_1 Belongs to the globin family - - - 0.000000000000000000003708 96.0
PYH2_k127_7699842_0 type IV-A pilus assembly ATPase PilB K02652 - - 4.614e-251 786.0
PYH2_k127_7699842_1 PFAM type II secretion system K02653 - - 2.504e-201 632.0
PYH2_k127_7699842_2 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 470.0
PYH2_k127_7707870_0 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 305.0
PYH2_k127_7707870_1 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000006222 175.0
PYH2_k127_7708946_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.28e-302 940.0
PYH2_k127_7708946_1 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 312.0
PYH2_k127_7708946_2 Two-component sensor kinase N-terminal K07645 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000007648 121.0
PYH2_k127_7710042_0 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000003852 180.0
PYH2_k127_7710042_1 Histidine kinase-like ATPases - - - 0.00000005334 55.0
PYH2_k127_7710042_2 - - - - 0.000005975 57.0
PYH2_k127_7710070_0 AcrB/AcrD/AcrF family K03296 - - 1.169e-280 880.0
PYH2_k127_7718_0 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 548.0
PYH2_k127_7718_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 515.0
PYH2_k127_7718_2 Mechanosensitive ion channel K05802,K22051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 389.0
PYH2_k127_7718_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
PYH2_k127_7718_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000001431 241.0
PYH2_k127_7718_5 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000002256 137.0
PYH2_k127_7718_6 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000001255 132.0
PYH2_k127_7718_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002148 90.0
PYH2_k127_7718_8 amidohydrolase - - - 0.0000000006493 63.0
PYH2_k127_7738562_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 544.0
PYH2_k127_7738562_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
PYH2_k127_7738562_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000003232 221.0
PYH2_k127_7738562_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000002158 135.0
PYH2_k127_7752288_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.117e-217 683.0
PYH2_k127_7752288_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 553.0
PYH2_k127_7752288_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
PYH2_k127_7755380_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 385.0
PYH2_k127_7755380_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 367.0
PYH2_k127_7772318_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 477.0
PYH2_k127_777642_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 312.0
PYH2_k127_777642_1 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000000000000000000000001184 247.0
PYH2_k127_777642_2 nitrogen regulatory protein PII - - - 0.000000000146 62.0
PYH2_k127_7777035_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000005346 207.0
PYH2_k127_7777035_1 MazG-like family - - - 0.00000000000000000000000000000000002819 138.0
PYH2_k127_7777035_2 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000002769 118.0
PYH2_k127_7777035_3 GDSL-like Lipase/Acylhydrolase - - - 0.000001067 61.0
PYH2_k127_7792933_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 6.12e-267 834.0
PYH2_k127_7801224_0 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
PYH2_k127_7801224_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
PYH2_k127_7801224_2 glutaminyl-tRNA K01886 - 6.1.1.18 0.0000000000000000000000000001707 115.0
PYH2_k127_7801224_3 LysR substrate binding domain - - - 0.0000000000001705 71.0
PYH2_k127_7812785_0 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
PYH2_k127_7812785_1 - - - - 0.0000000000000000000000000000000004505 149.0
PYH2_k127_7818372_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.107e-301 928.0
PYH2_k127_7818372_1 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.716e-220 690.0
PYH2_k127_7818372_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 576.0
PYH2_k127_7818372_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 317.0
PYH2_k127_7818372_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
PYH2_k127_7818372_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000002499 89.0
PYH2_k127_7818386_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 498.0
PYH2_k127_7818386_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
PYH2_k127_7818386_2 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 254.0
PYH2_k127_7828197_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
PYH2_k127_7828197_1 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.00000000000000000000000000000000000000000000000000000000000135 216.0
PYH2_k127_7863299_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.614e-250 784.0
PYH2_k127_7863299_1 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000001033 183.0
PYH2_k127_7863299_2 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000003956 136.0
PYH2_k127_7863299_3 - - - - 0.0005123 43.0
PYH2_k127_7913478_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 578.0
PYH2_k127_7913478_1 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 376.0
PYH2_k127_7913478_2 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
PYH2_k127_7913478_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000003966 128.0
PYH2_k127_7913478_4 Thioredoxin domain - - - 0.000000000000000000000000984 105.0
PYH2_k127_7928276_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 523.0
PYH2_k127_7928276_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000009515 214.0
PYH2_k127_7928276_2 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000006339 184.0
PYH2_k127_7961362_0 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000124 202.0
PYH2_k127_7961362_1 anaerobic respiration - - - 0.0000000000000000000000000000002785 129.0
PYH2_k127_7967927_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1172.0
PYH2_k127_7967927_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 361.0
PYH2_k127_7971607_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 534.0
PYH2_k127_7971607_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000002725 108.0
PYH2_k127_7992924_0 Transport of potassium into the cell K03549 - - 4.359e-273 852.0
PYH2_k127_7992924_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000001911 136.0
PYH2_k127_8035385_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.369e-287 886.0
PYH2_k127_8035385_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000074 258.0
PYH2_k127_8035385_2 membrane - - - 0.0000000000000000000000000000000000000000008664 162.0
PYH2_k127_8035385_3 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000003372 128.0
PYH2_k127_8035385_4 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000135 75.0
PYH2_k127_8059009_0 Nitronate monooxygenase K00459 - 1.13.12.16 6.932e-224 701.0
PYH2_k127_8059009_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 563.0
PYH2_k127_8059009_2 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
PYH2_k127_8059009_3 - - - - 0.0000000001359 67.0
PYH2_k127_8059009_4 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0006269 47.0
PYH2_k127_8069004_0 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 399.0
PYH2_k127_8069004_1 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
PYH2_k127_8079243_0 - - - - 0.000000000000000000000000000002832 123.0
PYH2_k127_8079243_1 Transcriptional regulator - - - 0.0000000000000001657 83.0
PYH2_k127_8079243_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000008283 72.0
PYH2_k127_8079243_3 - - - - 0.00000003508 60.0
PYH2_k127_8079243_4 Beta-lactamase - - - 0.00007403 48.0
PYH2_k127_8083584_0 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 8.784e-309 952.0
PYH2_k127_8083584_1 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 451.0
PYH2_k127_8083584_2 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 391.0
PYH2_k127_8083584_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
PYH2_k127_8083584_4 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 281.0
PYH2_k127_8083584_5 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006899 276.0
PYH2_k127_8083584_6 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000001025 144.0
PYH2_k127_8088851_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 472.0
PYH2_k127_8088851_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 360.0
PYH2_k127_8088851_2 Protein of unknown function DUF72 - - - 0.000000009758 59.0
PYH2_k127_811572_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.42e-302 939.0
PYH2_k127_811572_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000637 162.0
PYH2_k127_811572_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000006989 164.0
PYH2_k127_811572_3 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000000000008226 89.0
PYH2_k127_8138163_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 402.0
PYH2_k127_8138163_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000001345 194.0
PYH2_k127_8138163_2 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.0000000000000000000000000000006386 126.0
PYH2_k127_8138163_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000333 60.0
PYH2_k127_8138435_0 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 375.0
PYH2_k127_8138435_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
PYH2_k127_8138435_2 Ammonium Transporter K03320,K06580 - - 0.00000000000000002737 81.0
PYH2_k127_8138435_3 TIR domain - - - 0.0000000001253 68.0
PYH2_k127_8142969_0 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
PYH2_k127_8142969_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002046 270.0
PYH2_k127_8142969_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
PYH2_k127_8142969_3 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000001392 168.0
PYH2_k127_8142969_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000003609 152.0
PYH2_k127_8142969_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000001447 119.0
PYH2_k127_8142969_6 psiF repeat - - - 0.00000000000000000001688 102.0
PYH2_k127_8234633_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.067e-296 918.0
PYH2_k127_8234633_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 459.0
PYH2_k127_8234633_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001006 280.0
PYH2_k127_8253845_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 545.0
PYH2_k127_8253845_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 336.0
PYH2_k127_8265777_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 516.0
PYH2_k127_8265777_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001224 273.0
PYH2_k127_8265777_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000001914 96.0
PYH2_k127_8267921_0 TonB-dependent receptor K02014 - - 1.041e-216 702.0
PYH2_k127_8267921_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 385.0
PYH2_k127_8267921_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002245 261.0
PYH2_k127_8267921_3 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006639 253.0
PYH2_k127_8267921_4 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
PYH2_k127_8277720_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 391.0
PYH2_k127_8277720_1 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000009448 201.0
PYH2_k127_8277720_2 - - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
PYH2_k127_8277720_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000001183 182.0
PYH2_k127_8282157_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 597.0
PYH2_k127_8282157_1 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000001226 211.0
PYH2_k127_8282157_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000003076 148.0
PYH2_k127_8282157_3 Ribosomal protein S18 K02963 - - 0.00000000000000000000000000000000006314 134.0
PYH2_k127_8282157_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000003378 113.0
PYH2_k127_8291896_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 2.061e-293 911.0
PYH2_k127_8291896_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 1.862e-200 627.0
PYH2_k127_8291896_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 322.0
PYH2_k127_8291896_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000107 217.0
PYH2_k127_8291896_4 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000003127 164.0
PYH2_k127_8291896_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000008188 135.0
PYH2_k127_8291896_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000009597 110.0
PYH2_k127_8297230_0 Tetratricopeptide repeat K02200 - - 0.0000000000000000000000000000000000003487 142.0
PYH2_k127_8297230_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000003326 100.0
PYH2_k127_8297230_2 Thioredoxin-like - - - 0.0005538 45.0
PYH2_k127_8322456_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0 1022.0
PYH2_k127_8322456_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003743 251.0
PYH2_k127_8322456_2 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000001256 195.0
PYH2_k127_8322456_3 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000008667 190.0
PYH2_k127_8322456_4 - - - - 0.0000000000000000000000000007224 119.0
PYH2_k127_8322456_5 YMGG-like Gly-zipper - - - 0.0000005215 51.0
PYH2_k127_8357741_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 8.453e-214 685.0
PYH2_k127_8357741_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000007442 171.0
PYH2_k127_8366016_0 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 389.0
PYH2_k127_8366016_1 biosynthesis protein E K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005499 275.0
PYH2_k127_8366016_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000008761 217.0
PYH2_k127_8366016_3 Coenzyme PQQ synthesis protein D (PqqD) K06138 - - 0.0000002931 62.0
PYH2_k127_8374221_0 Cytochrome b(N-terminal)/b6/petB - - - 1.96e-253 797.0
PYH2_k127_8374221_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000417 275.0
PYH2_k127_8374221_2 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004112 258.0
PYH2_k127_8374221_3 - - - - 0.0000000000000000000000000000000000000003371 155.0
PYH2_k127_8376715_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.83e-253 784.0
PYH2_k127_8376715_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.101e-235 744.0
PYH2_k127_8376715_2 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 529.0
PYH2_k127_8376715_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
PYH2_k127_8376715_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
PYH2_k127_8376715_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
PYH2_k127_8398179_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 3.854e-194 611.0
PYH2_k127_8398179_1 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 382.0
PYH2_k127_8398179_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003005 235.0
PYH2_k127_8398179_3 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000005207 164.0
PYH2_k127_8398179_4 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000003336 108.0
PYH2_k127_8406292_0 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008869 246.0
PYH2_k127_8432141_0 Ammonium transporter K03320 - - 1.861e-218 685.0
PYH2_k127_8432141_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 431.0
PYH2_k127_8432141_2 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000921 124.0
PYH2_k127_8461119_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 342.0
PYH2_k127_8461119_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000008475 211.0
PYH2_k127_8461119_2 - - - - 0.00000000000000000000000000000000000000000000000007419 202.0
PYH2_k127_8461119_3 Chaperone - - - 0.0000000000000000000000000000000000000000000000001227 188.0
PYH2_k127_8461119_4 - - - - 0.00000000005797 73.0
PYH2_k127_8461119_5 - - - - 0.000000007655 64.0
PYH2_k127_8496378_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 352.0
PYH2_k127_8496378_1 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000597 241.0
PYH2_k127_8521479_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.437e-208 653.0
PYH2_k127_8521479_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 497.0
PYH2_k127_8521479_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 387.0
PYH2_k127_8521479_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001086 57.0
PYH2_k127_8525247_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1065.0
PYH2_k127_8525247_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000001622 189.0
PYH2_k127_8525247_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000002175 61.0
PYH2_k127_8550670_0 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 398.0
PYH2_k127_8556943_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1370.0
PYH2_k127_8556943_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 346.0
PYH2_k127_8556943_2 Protein of unknown function (DUF2863) - - - 0.00000000000000000000000000000000000000000000001305 178.0
PYH2_k127_8559509_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 320.0
PYH2_k127_8559509_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000646 104.0
PYH2_k127_8559509_2 Acyl carrier protein phosphodiesterase - - - 0.00000000000000003204 81.0
PYH2_k127_8560672_0 4Fe-4S dicluster domain - - - 1.276e-232 745.0
PYH2_k127_8560672_1 Protein of unknown function (DUF3306) - - - 0.000000000000000000000005181 106.0
PYH2_k127_8566819_0 PFAM ATPase associated with various cellular activities, AAA_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 480.0
PYH2_k127_8566819_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000003338 133.0
PYH2_k127_8568029_0 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.0000000000000000000000000001757 125.0
PYH2_k127_8568029_1 HPP family K07168 - - 0.00000000000000000001369 95.0
PYH2_k127_8568029_2 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000001097 92.0
PYH2_k127_8568029_3 - - - - 0.0000000000008255 72.0
PYH2_k127_8573729_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 511.0
PYH2_k127_8573729_1 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
PYH2_k127_8573729_2 FR47-like protein - - - 0.00000000000000000000001878 113.0
PYH2_k127_8583193_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 7.507e-224 709.0
PYH2_k127_8596187_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.024e-265 831.0
PYH2_k127_8596187_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.553e-228 712.0
PYH2_k127_8596187_2 Isocitrate lyase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
PYH2_k127_8596187_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 238.0
PYH2_k127_8620274_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 7.482e-229 712.0
PYH2_k127_8620274_1 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 315.0
PYH2_k127_8620274_2 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
PYH2_k127_8620274_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000236 152.0
PYH2_k127_8620274_4 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000006096 84.0
PYH2_k127_8626274_0 Belongs to the peptidase S8 family - - - 7.676e-208 655.0
PYH2_k127_8626274_1 Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
PYH2_k127_8628921_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 481.0
PYH2_k127_8628921_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 328.0
PYH2_k127_8628921_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000009705 185.0
PYH2_k127_8628921_3 transcriptional - - - 0.0000000000000000000000000000000000000000000000006546 178.0
PYH2_k127_8631189_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 506.0
PYH2_k127_8631189_1 - - - - 0.0000000000000000000000000000000000000000000000000000000131 220.0
PYH2_k127_8639047_0 Participates in both transcription termination and antitermination K02600 - - 6.09e-235 735.0
PYH2_k127_8639047_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000005568 149.0
PYH2_k127_8652229_0 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 502.0
PYH2_k127_8652229_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 389.0
PYH2_k127_8652229_2 DNA mismatch repair protein, C-terminal domain K03572 - - 0.00000000000000000000000000000000000001221 146.0
PYH2_k127_8652229_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000002224 145.0
PYH2_k127_8653017_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.485e-297 927.0
PYH2_k127_8653017_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.115e-232 728.0
PYH2_k127_8653017_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 549.0
PYH2_k127_8653017_3 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 442.0
PYH2_k127_8653017_4 GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
PYH2_k127_8653017_5 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000004513 166.0
PYH2_k127_8653017_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000009741 128.0
PYH2_k127_8653017_7 Dehydrogenase E1 component K00164 - 1.2.4.2 0.000000000000000000005159 96.0
PYH2_k127_8653017_8 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000005172 77.0
PYH2_k127_8663843_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.549e-215 681.0
PYH2_k127_8663843_1 protein conserved in bacteria K03690 - - 0.00000000007741 65.0
PYH2_k127_8674147_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 359.0
PYH2_k127_8674147_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000009673 241.0
PYH2_k127_8674147_2 Ferredoxin - - - 0.00000000000000000000000000000000000004365 143.0
PYH2_k127_8674147_3 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000004087 131.0
PYH2_k127_8674147_4 Methyltransferase K08316 - 2.1.1.171 0.00000934 48.0
PYH2_k127_8674147_5 Ankyrin repeats (many copies) - GO:0003008,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006996,GO:0007010,GO:0007015,GO:0007600,GO:0007605,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0032420,GO:0032421,GO:0032426,GO:0032501,GO:0042995,GO:0043005,GO:0043226,GO:0044085,GO:0044422,GO:0044424,GO:0044463,GO:0044464,GO:0044877,GO:0050877,GO:0050954,GO:0051015,GO:0051017,GO:0061572,GO:0071840,GO:0097435,GO:0097458,GO:0098858,GO:0098862,GO:0120025,GO:0120038 - 0.00009613 48.0
PYH2_k127_8679087_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.199e-205 655.0
PYH2_k127_8679087_1 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
PYH2_k127_8708464_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 511.0
PYH2_k127_8708464_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 497.0
PYH2_k127_8708464_2 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 454.0
PYH2_k127_8708464_3 Protein conserved in bacteria - - - 0.000008339 52.0
PYH2_k127_8719883_0 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000003426 195.0
PYH2_k127_8719883_1 Parallel beta-helix repeats - - - 0.0000000000000000001339 104.0
PYH2_k127_8719883_2 Conserved repeat domain - - - 0.00000000001665 78.0
PYH2_k127_8721916_0 PFAM multicopper oxidase type 2 K22350 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 583.0
PYH2_k127_8721916_1 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000002662 136.0
PYH2_k127_8728662_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 493.0
PYH2_k127_8728662_1 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
PYH2_k127_8728662_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 319.0
PYH2_k127_8732034_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.111e-202 635.0
PYH2_k127_8732034_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 389.0
PYH2_k127_8732034_2 - - - - 0.000000000000000001589 100.0
PYH2_k127_8762317_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.077e-224 699.0
PYH2_k127_8762317_1 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 355.0
PYH2_k127_8762317_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 285.0
PYH2_k127_8762317_3 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 283.0
PYH2_k127_8762317_4 stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000001975 164.0
PYH2_k127_8762317_5 dinuclear metal center protein, YbgI - - - 0.000000000000000000000000000000000000605 140.0
PYH2_k127_8776289_0 Multicopper oxidase K22349 - 1.16.3.3 9.438e-284 883.0
PYH2_k127_8777721_0 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 379.0
PYH2_k127_8777721_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 295.0
PYH2_k127_8777721_2 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005361 277.0
PYH2_k127_8778572_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1709.0
PYH2_k127_8778572_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 588.0
PYH2_k127_8778572_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
PYH2_k127_8778572_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 450.0
PYH2_k127_8778572_4 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 359.0
PYH2_k127_8778572_5 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001362 212.0
PYH2_k127_8778572_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000442 119.0
PYH2_k127_8782356_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1413.0
PYH2_k127_8782933_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 9.927e-209 655.0
PYH2_k127_8782933_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 533.0
PYH2_k127_8782933_2 Histidine kinase K07637 - 2.7.13.3 0.000000000000000006412 84.0
PYH2_k127_8785850_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 387.0
PYH2_k127_8785850_1 sptr putative - - - 0.00000000000000002147 85.0
PYH2_k127_8785850_2 Alpha-L-rhamnosidase N-terminal domain protein - - - 0.000000008464 58.0
PYH2_k127_8791908_0 von Willebrand factor, type A - - - 0.0 1188.0
PYH2_k127_8791908_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
PYH2_k127_8791908_2 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
PYH2_k127_8791908_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000006059 216.0
PYH2_k127_8791908_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000000000005013 89.0
PYH2_k127_8816073_0 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006945 269.0
PYH2_k127_8816073_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000003571 176.0
PYH2_k127_8825437_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.062e-196 617.0
PYH2_k127_8825437_1 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 545.0
PYH2_k127_8825437_2 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
PYH2_k127_8825437_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000002201 198.0
PYH2_k127_8825437_4 - - - - 0.0001548 46.0
PYH2_k127_8840687_0 DNA polymerase III K02342 - 2.7.7.7 1.222e-238 757.0
PYH2_k127_8840687_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.21e-205 686.0
PYH2_k127_8840687_2 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 442.0
PYH2_k127_8840687_3 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 416.0
PYH2_k127_8840687_4 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000008179 175.0
PYH2_k127_8840687_5 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000001848 131.0
PYH2_k127_8850985_0 serine threonine protein kinase K12132 - 2.7.11.1 1.415e-260 815.0
PYH2_k127_8850985_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 359.0
PYH2_k127_8850985_2 (FHA) domain - - - 0.000000000000000000000000000000000000000000000001013 176.0
PYH2_k127_8870272_0 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 384.0
PYH2_k127_8870272_1 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000004603 132.0
PYH2_k127_8870272_2 DsrC like protein K11179 - - 0.0000000000000000000000000000001885 126.0
PYH2_k127_8876503_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.019e-251 784.0
PYH2_k127_8876503_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 543.0
PYH2_k127_8876503_2 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000001586 117.0
PYH2_k127_8876503_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000003564 94.0
PYH2_k127_8888196_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 531.0
PYH2_k127_8888196_1 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000118 199.0
PYH2_k127_8889763_0 Periplasmic copper-binding protein (NosD) K07218 - - 3.83e-214 669.0
PYH2_k127_8889763_1 (ABC) transporter K19340 - - 0.000000000000000000000000000000000000000000341 162.0
PYH2_k127_891381_0 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 568.0
PYH2_k127_891381_1 Diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
PYH2_k127_8929003_0 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
PYH2_k127_8929003_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000007177 144.0
PYH2_k127_8929003_2 Outer membrane lipoprotein K07285 - - 0.00001155 52.0
PYH2_k127_8932058_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 589.0
PYH2_k127_8932058_1 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 392.0
PYH2_k127_8932058_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000001773 192.0
PYH2_k127_8932058_3 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000000966 144.0
PYH2_k127_8932058_4 protein conserved in bacteria K11719 - - 0.000000000000000173 81.0
PYH2_k127_8946435_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1004.0
PYH2_k127_8946435_1 Dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000001752 154.0
PYH2_k127_8946435_2 Pfam Glutaredoxin - - - 0.00000000000000000000000000002104 137.0
PYH2_k127_8947023_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 2.371e-290 898.0
PYH2_k127_8947023_1 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
PYH2_k127_8950433_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 374.0
PYH2_k127_8950433_1 - - - - 0.0000001141 58.0
PYH2_k127_8954276_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000008895 263.0
PYH2_k127_8954276_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
PYH2_k127_8954276_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000007072 171.0
PYH2_k127_8954276_3 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000002155 132.0
PYH2_k127_8954276_4 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000001809 114.0
PYH2_k127_8954964_0 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
PYH2_k127_8954964_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000004864 205.0
PYH2_k127_8954964_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000005727 186.0
PYH2_k127_8954964_3 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000009941 153.0
PYH2_k127_8954964_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000001537 119.0
PYH2_k127_8954964_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000004797 107.0
PYH2_k127_8968769_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.693e-270 841.0
PYH2_k127_8968769_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
PYH2_k127_8968769_2 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000007996 66.0
PYH2_k127_8969792_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 526.0
PYH2_k127_8969792_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
PYH2_k127_8969792_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000142 121.0
PYH2_k127_8969899_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 8.571e-196 621.0
PYH2_k127_8969899_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 418.0
PYH2_k127_8969899_2 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000006827 254.0
PYH2_k127_8979925_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.937e-265 822.0
PYH2_k127_8979925_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 543.0
PYH2_k127_8979925_2 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 422.0
PYH2_k127_8979925_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 409.0
PYH2_k127_8979925_4 - - - - 0.0000000000001209 78.0
PYH2_k127_8979925_5 - - - - 0.000000000000278 81.0
PYH2_k127_8979925_6 Major Facilitator Superfamily - - - 0.0003006 46.0
PYH2_k127_8993026_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.161e-219 688.0
PYH2_k127_8993026_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
PYH2_k127_8993026_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000009445 53.0
PYH2_k127_8993077_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 584.0
PYH2_k127_8993077_1 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
PYH2_k127_8994323_0 protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 514.0
PYH2_k127_8994323_1 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 482.0
PYH2_k127_8994323_2 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000003318 160.0
PYH2_k127_8994479_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 518.0
PYH2_k127_8994479_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 460.0
PYH2_k127_8994479_2 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000006412 229.0
PYH2_k127_8996537_0 Glutamate-cysteine ligase K01919 - 6.3.2.2 1.278e-216 679.0
PYH2_k127_8996537_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 338.0
PYH2_k127_8996537_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 316.0
PYH2_k127_8996817_0 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 349.0
PYH2_k127_8996817_1 - - - - 0.00000000000000006976 83.0
PYH2_k127_8996817_2 - - - - 0.0000000000001122 73.0
PYH2_k127_9001196_0 Transcriptional regulator, Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
PYH2_k127_9001196_1 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
PYH2_k127_9007773_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 424.0
PYH2_k127_9007773_1 response to hydrogen peroxide K08985 - - 0.0000001592 61.0
PYH2_k127_9017337_0 DNA polymerase X family K02347 - - 1.544e-256 802.0
PYH2_k127_9017337_1 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000005802 143.0
PYH2_k127_9037530_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 532.0
PYH2_k127_9037530_1 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 475.0
PYH2_k127_9037530_2 Zinc-finger domain - - - 0.0000000000000000000000000002722 114.0
PYH2_k127_9037530_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000001446 53.0
PYH2_k127_9037725_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002773 235.0
PYH2_k127_9037725_1 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000000000000000000000002564 207.0
PYH2_k127_9078025_0 4Fe-4S double cluster binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 597.0
PYH2_k127_9078025_1 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000002785 129.0
PYH2_k127_9078025_2 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000008188 107.0
PYH2_k127_9078025_3 SdpI/YhfL protein family - - - 0.000000000000000002185 96.0
PYH2_k127_9079065_0 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 432.0
PYH2_k127_9079065_1 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000001216 166.0
PYH2_k127_9079065_2 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.00000000000000000000000000000007329 129.0
PYH2_k127_9079065_3 MerR HTH family regulatory protein K18997 - - 0.00006045 46.0
PYH2_k127_9085668_0 Cysteine-rich domain - - - 8.387e-229 718.0
PYH2_k127_9085668_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
PYH2_k127_9085668_2 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004279 258.0
PYH2_k127_9085668_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000004008 213.0
PYH2_k127_9090798_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 8.035e-263 816.0
PYH2_k127_9090798_1 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 350.0
PYH2_k127_9091757_0 TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA K03694 - - 0.0 1179.0
PYH2_k127_9091757_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 329.0
PYH2_k127_9091757_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
PYH2_k127_9091757_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000005339 162.0
PYH2_k127_9091757_4 cytochrome - - - 0.0000000000000002858 83.0
PYH2_k127_9101962_0 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 428.0
PYH2_k127_9101962_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000008254 226.0
PYH2_k127_9109069_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 340.0
PYH2_k127_9109069_1 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001404 247.0
PYH2_k127_9109069_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000002152 145.0
PYH2_k127_9109069_3 - - - - 0.000000000000006385 81.0
PYH2_k127_9127600_0 Malic enzyme K00029 - 1.1.1.40 0.0 1044.0
PYH2_k127_9132008_0 PA domain - - - 2.72e-200 638.0
PYH2_k127_9132008_1 Redoxin - - - 0.0000000000000002846 81.0
PYH2_k127_9140031_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 397.0
PYH2_k127_9140031_1 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
PYH2_k127_9140031_2 - - - - 0.0000000000000000000000000000000000000000004344 169.0
PYH2_k127_9140031_3 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000000000001823 113.0
PYH2_k127_9140031_4 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000002257 102.0
PYH2_k127_9140031_5 Glycosyl transferase family 1 - - - 0.000000000009878 69.0
PYH2_k127_9143440_0 Multicopper oxidase K22349 - 1.16.3.3 3.972e-277 876.0
PYH2_k127_914422_0 Molecular chaperone. Has ATPase activity K04079 - - 3.79e-293 913.0
PYH2_k127_914422_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.689e-204 645.0
PYH2_k127_914422_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 359.0
PYH2_k127_914422_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 357.0
PYH2_k127_914422_4 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 305.0
PYH2_k127_914422_5 Belongs to the enoyl-CoA hydratase isomerase family K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001028 265.0
PYH2_k127_914422_6 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000136 246.0
PYH2_k127_914422_7 Ribonuclease T2 family - - - 0.00000000000000000000000000000000000000000001353 179.0
PYH2_k127_9150032_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
PYH2_k127_9150032_1 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000001377 144.0
PYH2_k127_9153777_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.035e-232 725.0
PYH2_k127_9153777_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 356.0
PYH2_k127_9153777_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000001522 203.0
PYH2_k127_9153777_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000001485 158.0
PYH2_k127_9153777_4 - - - - 0.00000000000000000000002916 104.0
PYH2_k127_9153777_5 - - - - 0.000000000000000000001682 96.0
PYH2_k127_9159941_0 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 424.0
PYH2_k127_9159941_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001553 270.0
PYH2_k127_9159941_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000009832 73.0
PYH2_k127_9188608_0 Belongs to the malate synthase family K01638 - 2.3.3.9 5.336e-278 864.0
PYH2_k127_9188608_1 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 565.0
PYH2_k127_9188608_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 357.0
PYH2_k127_9188608_3 (ABC) transporter K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 299.0
PYH2_k127_9188608_4 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
PYH2_k127_9188608_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000107 210.0
PYH2_k127_9188608_6 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000003481 170.0
PYH2_k127_9211130_0 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 246.0
PYH2_k127_9211130_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000001297 189.0
PYH2_k127_9214725_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.969e-228 715.0
PYH2_k127_9214725_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 426.0
PYH2_k127_9214725_2 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
PYH2_k127_9214725_3 Phasin protein - - - 0.00000000000000000000000000000000000000003474 159.0
PYH2_k127_9214725_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000202 139.0
PYH2_k127_9214725_5 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000009353 48.0
PYH2_k127_9247792_0 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 3.103e-221 694.0
PYH2_k127_9247792_1 Aminotransferase class I and II K14261 - - 2.565e-209 655.0
PYH2_k127_9247792_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 286.0
PYH2_k127_9247792_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000002476 81.0
PYH2_k127_9254361_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 5.231e-279 865.0
PYH2_k127_9254361_1 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002328 273.0
PYH2_k127_9254361_2 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000002904 179.0
PYH2_k127_9258890_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 591.0
PYH2_k127_9258890_1 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 293.0
PYH2_k127_9258890_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002992 213.0
PYH2_k127_9258890_3 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000002385 162.0
PYH2_k127_9258890_4 - - - - 0.0004391 44.0
PYH2_k127_9261223_0 transposition - - - 2.719e-197 623.0
PYH2_k127_9261223_1 DDE superfamily endonuclease - - - 0.0002799 46.0
PYH2_k127_926488_0 Ferrous iron transport protein B K04759 - - 4.529e-252 792.0
PYH2_k127_926488_1 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000001363 199.0
PYH2_k127_926488_2 FeoA K04758 - - 0.0000000000001765 71.0
PYH2_k127_9314650_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 357.0
PYH2_k127_9314650_1 DNA integration K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 336.0
PYH2_k127_9314650_2 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 310.0
PYH2_k127_9314650_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.00000000006714 64.0
PYH2_k127_9314650_4 - - - - 0.0000009202 58.0
PYH2_k127_947572_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1337.0
PYH2_k127_947572_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 444.0
PYH2_k127_950138_0 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
PYH2_k127_950138_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 518.0
PYH2_k127_950138_2 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
PYH2_k127_950138_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000962 162.0
PYH2_k127_972501_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 567.0
PYH2_k127_972501_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
PYH2_k127_972501_2 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001636 208.0
PYH2_k127_972501_3 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000002988 202.0
PYH2_k127_972600_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 467.0
PYH2_k127_972600_1 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 405.0
PYH2_k127_972600_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 302.0
PYH2_k127_972600_3 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.00000000000000033 82.0
PYH2_k127_988922_0 Domain of unknown function (DUF3400) - - - 0.0 1803.0
PYH2_k127_988922_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 389.0
PYH2_k127_988922_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 338.0
PYH2_k127_988922_3 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000001152 213.0
PYH2_k127_988922_4 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000001285 177.0
PYH2_k127_995033_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.0 1280.0
PYH2_k127_996309_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 533.0
PYH2_k127_996309_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000001085 181.0