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Overview

ID MAG03197
Name PYH2_bin.49
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family Dissulfurispiraceae
Genus
Species
Assembly information
Completeness (%) 89.23
Contamination (%) 0.14
GC content (%) 54.0
N50 (bp) 5,607
Genome size (bp) 2,083,969

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2064

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1006286_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 573.0
PYH2_k127_1006286_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 518.0
PYH2_k127_1006286_2 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 316.0
PYH2_k127_1006286_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000003026 200.0
PYH2_k127_1006286_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000004338 179.0
PYH2_k127_1006286_5 Ion channel - - - 0.000000000000000000000000000000000000000004502 164.0
PYH2_k127_1006286_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000001468 103.0
PYH2_k127_102123_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 3.552e-287 894.0
PYH2_k127_102123_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 499.0
PYH2_k127_102123_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 499.0
PYH2_k127_102123_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000001681 174.0
PYH2_k127_102123_4 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000004752 170.0
PYH2_k127_102123_5 Predicted RNA-binding protein - - - 0.0002962 43.0
PYH2_k127_102340_0 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000002816 250.0
PYH2_k127_102340_1 cyclic nucleotide binding K01420,K10716,K10914 - - 0.000000000000000000000000000000000000000000007808 171.0
PYH2_k127_102340_2 Cytochrome P460 - - - 0.0000000000000000000000001447 112.0
PYH2_k127_102340_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000005543 93.0
PYH2_k127_102340_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000005069 82.0
PYH2_k127_1031902_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.287e-278 863.0
PYH2_k127_1031902_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 559.0
PYH2_k127_1031902_10 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00001063 51.0
PYH2_k127_1031902_2 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 361.0
PYH2_k127_1031902_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 344.0
PYH2_k127_1031902_4 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009663 254.0
PYH2_k127_1031902_5 HDIG domain protein K06950 - - 0.00000000000000000000000000000000000000000000000000000000000001029 220.0
PYH2_k127_1031902_6 - - - - 0.00000000000000000000000001517 124.0
PYH2_k127_1031902_7 FlhB HrpN YscU SpaS Family K04061 - - 0.00000000000000000000000002375 111.0
PYH2_k127_1031902_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001594 108.0
PYH2_k127_1031902_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000002585 104.0
PYH2_k127_1040876_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 372.0
PYH2_k127_1040876_1 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 342.0
PYH2_k127_1040876_2 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 308.0
PYH2_k127_1040876_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000005033 227.0
PYH2_k127_1040876_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000002163 230.0
PYH2_k127_1040876_5 ABC transporter transmembrane region K11085 - - 0.0000000000000008905 78.0
PYH2_k127_1055485_0 membrane K09133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002224 265.0
PYH2_k127_1055485_1 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000000000296 201.0
PYH2_k127_1055485_2 Predicted RNA-binding protein - - - 0.0000000000000000000002562 97.0
PYH2_k127_1055725_0 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 293.0
PYH2_k127_1055725_1 Universal stress protein family - - - 0.0000000000000000000000000000000000009432 144.0
PYH2_k127_1055725_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002306 68.0
PYH2_k127_1063938_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.097e-244 764.0
PYH2_k127_1063938_1 lipolytic protein G-D-S-L family - - - 0.00000000000001758 76.0
PYH2_k127_1063938_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000006262 66.0
PYH2_k127_1065786_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 486.0
PYH2_k127_1065786_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 323.0
PYH2_k127_1065786_2 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000002238 238.0
PYH2_k127_1065786_3 Cytochrome c554 and c-prime - - - 0.00000000199 63.0
PYH2_k127_1110726_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 471.0
PYH2_k127_1110726_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 459.0
PYH2_k127_1110726_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
PYH2_k127_1110726_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 291.0
PYH2_k127_1110726_4 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001847 255.0
PYH2_k127_1110726_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000002006 183.0
PYH2_k127_1110726_6 PHB de-polymerase C-terminus K03821 - - 0.0000000000002244 70.0
PYH2_k127_1119799_0 Sugar (and other) transporter K03446 - - 7.274e-232 727.0
PYH2_k127_1119799_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 7.963e-200 629.0
PYH2_k127_1119799_2 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 571.0
PYH2_k127_1119799_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 297.0
PYH2_k127_1119799_4 SMART Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000000000000005849 192.0
PYH2_k127_1119799_5 TPM domain - - - 0.000000000000000000000000000000000000000002767 166.0
PYH2_k127_1119799_6 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000001263 122.0
PYH2_k127_1119799_7 nucleotidyltransferase activity - - - 0.000000000000000000000000001256 124.0
PYH2_k127_1119799_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000000000001264 114.0
PYH2_k127_1119799_9 Ribbon-helix-helix protein, copG family - - - 0.0002392 47.0
PYH2_k127_1223831_0 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000003667 214.0
PYH2_k127_1223831_1 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000001821 192.0
PYH2_k127_1223831_2 Cellulose biosynthesis protein BcsQ K04562 - - 0.0000000000000000000000000000002577 126.0
PYH2_k127_1223831_3 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000001484 125.0
PYH2_k127_1223831_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000001559 113.0
PYH2_k127_1223831_5 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.000002494 52.0
PYH2_k127_1238438_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
PYH2_k127_1238438_1 -acetyltransferase - - - 0.0000000000000000000000000000000000005469 149.0
PYH2_k127_1245947_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.845e-280 871.0
PYH2_k127_1245947_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000004129 224.0
PYH2_k127_1250274_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.259e-300 929.0
PYH2_k127_1250274_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.101e-213 677.0
PYH2_k127_1250274_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 381.0
PYH2_k127_1250274_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
PYH2_k127_1250274_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000001728 54.0
PYH2_k127_125257_0 GAF domain - - - 2.45e-219 707.0
PYH2_k127_125257_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 557.0
PYH2_k127_125257_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 508.0
PYH2_k127_125257_3 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
PYH2_k127_125257_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 355.0
PYH2_k127_125257_5 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 352.0
PYH2_k127_125257_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 283.0
PYH2_k127_1309980_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 582.0
PYH2_k127_1309980_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 325.0
PYH2_k127_1337373_0 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005819 286.0
PYH2_k127_1337373_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003517 253.0
PYH2_k127_1337373_2 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001009 232.0
PYH2_k127_1349121_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 373.0
PYH2_k127_1349121_1 deoxyhypusine monooxygenase activity K05386 - - 0.000000000000000005225 90.0
PYH2_k127_1350716_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 2.371e-196 624.0
PYH2_k127_1350716_1 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 349.0
PYH2_k127_1350716_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004985 241.0
PYH2_k127_1350716_3 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000000000008248 127.0
PYH2_k127_1350716_4 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.00000000102 70.0
PYH2_k127_1350716_5 GAF domain - - - 0.0000002905 63.0
PYH2_k127_1352798_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.953e-244 765.0
PYH2_k127_1352798_1 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000002851 87.0
PYH2_k127_1355550_0 Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003086 259.0
PYH2_k127_1355550_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001298 253.0
PYH2_k127_1355550_2 - - - - 0.0000000000000000000000000000000006824 132.0
PYH2_k127_1355550_3 Tetratricopeptide repeat - - - 0.0000000000000000000000007643 116.0
PYH2_k127_1355550_4 NADH dehydrogenase K03885 - 1.6.99.3 0.00003364 50.0
PYH2_k127_1372459_0 Cation transporter/ATPase, N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000086 281.0
PYH2_k127_1372459_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000001982 162.0
PYH2_k127_1372459_2 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000187 146.0
PYH2_k127_1372459_4 PFAM YeeE YedE family (DUF395) K07112 - - 0.0000007645 51.0
PYH2_k127_1457373_0 - - - - 0.000000000000000000000000000000000000000000000000001358 195.0
PYH2_k127_1457373_1 - - - - 0.0000000006756 61.0
PYH2_k127_1457373_2 Glycine-zipper domain - - - 0.0000004239 52.0
PYH2_k127_1457373_3 - - - - 0.0001254 46.0
PYH2_k127_1492914_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 481.0
PYH2_k127_1492914_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 449.0
PYH2_k127_1492914_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 378.0
PYH2_k127_1492914_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009817 242.0
PYH2_k127_1492914_4 DivIVA protein K04074 - - 0.0000000000000000000000000000000000003604 141.0
PYH2_k127_1520804_0 - - - - 0.0000000000000000000000000000007185 127.0
PYH2_k127_1520804_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000002026 112.0
PYH2_k127_1520804_3 PIN domain - - - 0.000001146 57.0
PYH2_k127_1520804_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00001739 51.0
PYH2_k127_1520804_5 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0002488 47.0
PYH2_k127_1551958_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 437.0
PYH2_k127_1551958_1 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 359.0
PYH2_k127_1551958_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000004895 211.0
PYH2_k127_1568268_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.027e-237 743.0
PYH2_k127_1568268_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000001933 87.0
PYH2_k127_1575845_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 359.0
PYH2_k127_1575845_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000054 199.0
PYH2_k127_1575845_2 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000009811 194.0
PYH2_k127_1617037_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.138e-203 643.0
PYH2_k127_1617037_1 Mazg nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000008141 134.0
PYH2_k127_1617037_2 Cupin 2, conserved barrel domain protein - - - 0.000000000008799 69.0
PYH2_k127_167465_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 419.0
PYH2_k127_167465_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000886 213.0
PYH2_k127_1696427_0 Subtilase family K20486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 392.0
PYH2_k127_1696427_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 331.0
PYH2_k127_1696427_2 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000111 280.0
PYH2_k127_1696427_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000003432 226.0
PYH2_k127_1696427_4 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000003064 220.0
PYH2_k127_1696427_5 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000002866 219.0
PYH2_k127_1696427_6 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000001177 196.0
PYH2_k127_1696427_7 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.0000000000000000000000000009515 118.0
PYH2_k127_171090_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 412.0
PYH2_k127_171090_1 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 323.0
PYH2_k127_171090_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 301.0
PYH2_k127_1740692_0 FMN binding - - - 2.108e-278 862.0
PYH2_k127_1740692_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 394.0
PYH2_k127_1740692_2 Cupin domain - - - 0.000000000000000000000000000000000005273 143.0
PYH2_k127_1740692_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000001202 112.0
PYH2_k127_176611_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 7.472e-249 784.0
PYH2_k127_176611_1 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000482 278.0
PYH2_k127_176611_2 Transport of potassium into the cell K03549 - - 0.00000000000000002331 81.0
PYH2_k127_1817268_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 362.0
PYH2_k127_1817268_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 335.0
PYH2_k127_1817268_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 296.0
PYH2_k127_1817268_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007967 273.0
PYH2_k127_1817268_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000009722 66.0
PYH2_k127_1817268_5 CAAX protease self-immunity - - - 0.00000000322 68.0
PYH2_k127_1878583_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.031e-247 773.0
PYH2_k127_1878583_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 361.0
PYH2_k127_1878583_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 312.0
PYH2_k127_1879213_0 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 372.0
PYH2_k127_1880203_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 7.176e-208 651.0
PYH2_k127_1880203_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 353.0
PYH2_k127_1880203_2 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 349.0
PYH2_k127_1880203_3 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000009996 121.0
PYH2_k127_1880203_4 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.0000000000000000000000001814 108.0
PYH2_k127_1880203_6 - - - - 0.00000000094 62.0
PYH2_k127_1913447_0 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 473.0
PYH2_k127_1913447_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 376.0
PYH2_k127_1913447_2 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000004532 211.0
PYH2_k127_1914381_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000002759 190.0
PYH2_k127_1914381_1 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000000000000000000001518 172.0
PYH2_k127_1946284_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.842e-202 636.0
PYH2_k127_1946284_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 496.0
PYH2_k127_1946284_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 416.0
PYH2_k127_1946284_3 transposase activity - - - 0.0000000005569 61.0
PYH2_k127_1978549_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 529.0
PYH2_k127_1978549_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 406.0
PYH2_k127_1978549_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 337.0
PYH2_k127_1978549_3 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
PYH2_k127_1978549_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000005907 209.0
PYH2_k127_1978549_5 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000007562 161.0
PYH2_k127_1978549_6 thiosulfate sulfurtransferase activity - - - 0.00000293 53.0
PYH2_k127_1981560_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 595.0
PYH2_k127_1981560_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 310.0
PYH2_k127_1981560_2 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000002963 123.0
PYH2_k127_1981560_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000001881 116.0
PYH2_k127_1981560_4 - - - - 0.0000000000001305 71.0
PYH2_k127_198638_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 1.987e-247 775.0
PYH2_k127_198638_1 metal ion transmembrane transporter activity K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 553.0
PYH2_k127_198638_10 - - - - 0.0002999 44.0
PYH2_k127_198638_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 430.0
PYH2_k127_198638_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 421.0
PYH2_k127_198638_4 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 353.0
PYH2_k127_198638_5 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 334.0
PYH2_k127_198638_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 321.0
PYH2_k127_198638_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000001483 185.0
PYH2_k127_198638_8 Histidine kinase - - - 0.00000000000000000000000000000000000003944 151.0
PYH2_k127_198638_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000008254 95.0
PYH2_k127_2021191_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 6.038e-243 758.0
PYH2_k127_2021191_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 455.0
PYH2_k127_2021191_2 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 330.0
PYH2_k127_2021191_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000002512 242.0
PYH2_k127_2021191_4 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000000000000000001593 207.0
PYH2_k127_2021191_5 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000007619 179.0
PYH2_k127_2021191_6 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000001594 111.0
PYH2_k127_2021191_7 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000002068 59.0
PYH2_k127_2021191_8 carbon dioxide binding K04653,K04654 - - 0.00000007741 57.0
PYH2_k127_2067294_0 DHHA2 domain K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 549.0
PYH2_k127_2067294_1 5TMR of 5TMR-LYT - - - 0.00000000000000000000002128 108.0
PYH2_k127_2085927_0 His Kinase A (phosphoacceptor) domain - - - 1.339e-250 793.0
PYH2_k127_2085927_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.02e-199 635.0
PYH2_k127_2085927_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000004104 216.0
PYH2_k127_2085927_3 Universal stress protein - - - 0.000000001543 61.0
PYH2_k127_2109745_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 349.0
PYH2_k127_2109745_1 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000002687 241.0
PYH2_k127_2109745_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000003106 211.0
PYH2_k127_2111832_0 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 461.0
PYH2_k127_2123980_0 histidine kinase HAMP region domain protein - - - 6.784e-229 741.0
PYH2_k127_2123980_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 5.102e-217 682.0
PYH2_k127_2123980_2 Putative diguanylate phosphodiesterase - - - 7.44e-210 675.0
PYH2_k127_2123980_3 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 594.0
PYH2_k127_2123980_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 583.0
PYH2_k127_2123980_5 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 307.0
PYH2_k127_2123980_6 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
PYH2_k127_2123980_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000001612 227.0
PYH2_k127_2123980_8 LysM domain - - - 0.00000000000000000000000000000000008995 147.0
PYH2_k127_2123980_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000006133 63.0
PYH2_k127_2129417_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 344.0
PYH2_k127_2129417_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000001586 196.0
PYH2_k127_2134055_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 599.0
PYH2_k127_2134055_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 549.0
PYH2_k127_2134055_10 - - - - 0.000000000000000000000001216 110.0
PYH2_k127_2134055_11 - - - - 0.000000000141 66.0
PYH2_k127_2134055_2 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 459.0
PYH2_k127_2134055_3 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 354.0
PYH2_k127_2134055_4 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 299.0
PYH2_k127_2134055_5 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 281.0
PYH2_k127_2134055_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001309 251.0
PYH2_k127_2134055_7 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000001364 221.0
PYH2_k127_2134055_8 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
PYH2_k127_2134055_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000001143 152.0
PYH2_k127_2146175_0 Heat shock 70 kDa protein K04043 - - 0.0 1018.0
PYH2_k127_2146175_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 526.0
PYH2_k127_2146175_10 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000004466 126.0
PYH2_k127_2146175_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 505.0
PYH2_k127_2146175_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 451.0
PYH2_k127_2146175_4 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 420.0
PYH2_k127_2146175_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 381.0
PYH2_k127_2146175_6 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000002967 236.0
PYH2_k127_2146175_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000004352 199.0
PYH2_k127_2146175_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000009325 172.0
PYH2_k127_2146175_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000009512 139.0
PYH2_k127_2149381_0 Large extracellular alpha-helical protein K06894 - - 0.0 2179.0
PYH2_k127_2149381_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 4.702e-239 758.0
PYH2_k127_2149381_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 468.0
PYH2_k127_2149381_3 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 292.0
PYH2_k127_2149381_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
PYH2_k127_2149381_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000001744 196.0
PYH2_k127_2182774_0 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 3.657e-208 653.0
PYH2_k127_2182774_1 Aminotransferase K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 509.0
PYH2_k127_2182774_2 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002653 236.0
PYH2_k127_2182774_3 methyltransferase - - - 0.000000000000000000000000000000000000000007516 163.0
PYH2_k127_2182774_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000001944 157.0
PYH2_k127_2182774_5 4Fe-4S binding domain - - - 0.0000000000000000000000000000009957 124.0
PYH2_k127_2182774_6 SMART Tetratricopeptide - - - 0.0000000000000000000000000004312 121.0
PYH2_k127_2182774_7 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000001028 98.0
PYH2_k127_2182774_8 - - - - 0.000000000008379 72.0
PYH2_k127_2202995_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.061e-233 743.0
PYH2_k127_2202995_1 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 390.0
PYH2_k127_2202995_2 RmlD substrate binding domain - - - 0.00000000000000000000000000000000001227 137.0
PYH2_k127_2202995_3 Tetratricopeptide repeat - - - 0.00000000000000000002377 100.0
PYH2_k127_2202995_4 - - - - 0.00001221 48.0
PYH2_k127_2236588_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 379.0
PYH2_k127_2236588_1 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001172 263.0
PYH2_k127_2236588_2 DHH family K07462 - - 0.0000000000000000000000000001012 119.0
PYH2_k127_2239383_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 423.0
PYH2_k127_2239383_1 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 410.0
PYH2_k127_2239383_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 403.0
PYH2_k127_2239383_3 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
PYH2_k127_2239383_4 SMART PAS domain containing protein - - - 0.00000000000008762 83.0
PYH2_k127_2239383_5 S23 ribosomal protein - - - 0.000003517 51.0
PYH2_k127_2242354_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 384.0
PYH2_k127_2242354_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000004202 252.0
PYH2_k127_2242354_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000000032 184.0
PYH2_k127_2242354_3 - - - - 0.00000000000000000000000000000000000001133 149.0
PYH2_k127_2259549_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 514.0
PYH2_k127_2259549_1 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 305.0
PYH2_k127_2259549_2 Flagellar basal body protein FlaE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 302.0
PYH2_k127_2259549_4 Flagellar assembly protein FliH K02411 - - 0.00000000003097 72.0
PYH2_k127_2259549_5 PFAM MgtE intracellular K02383 - - 0.0000001368 61.0
PYH2_k127_2259549_6 PFAM Flagellar hook-length control protein K02414 - - 0.00008315 55.0
PYH2_k127_2277310_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 394.0
PYH2_k127_2277310_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002132 245.0
PYH2_k127_2277853_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 515.0
PYH2_k127_2277853_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 433.0
PYH2_k127_2277853_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 332.0
PYH2_k127_2277853_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000005658 240.0
PYH2_k127_2277853_4 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000001795 200.0
PYH2_k127_2277853_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000776 136.0
PYH2_k127_2277853_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.000000000000000000006598 100.0
PYH2_k127_2277853_8 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000394 51.0
PYH2_k127_2278376_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 9.671e-316 979.0
PYH2_k127_2278376_1 O-methyltransferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000003538 214.0
PYH2_k127_2278376_2 Protein of unknown function (DUF1566) - - - 0.00000000000000000108 89.0
PYH2_k127_2280442_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 539.0
PYH2_k127_2280442_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 411.0
PYH2_k127_2280442_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000001751 241.0
PYH2_k127_2280442_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000002895 222.0
PYH2_k127_2294092_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 454.0
PYH2_k127_2294092_1 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 432.0
PYH2_k127_2294092_2 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 269.0
PYH2_k127_2296435_0 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 326.0
PYH2_k127_2296435_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 262.0
PYH2_k127_2296435_2 GDP-mannose mannosyl hydrolase activity K03574,K08320 - 3.6.1.55,3.6.1.65 0.0000000000000000000000000000000007627 136.0
PYH2_k127_2296435_3 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000008729 112.0
PYH2_k127_2299850_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 491.0
PYH2_k127_2299850_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 314.0
PYH2_k127_2303698_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 468.0
PYH2_k127_2322253_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1311.0
PYH2_k127_2322253_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000001033 175.0
PYH2_k127_232812_0 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
PYH2_k127_232812_1 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000254 241.0
PYH2_k127_232812_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002194 246.0
PYH2_k127_232812_3 Protein of unknown function with PCYCGC motif - - - 0.00002748 51.0
PYH2_k127_2380783_0 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 304.0
PYH2_k127_2380783_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000002964 253.0
PYH2_k127_2380783_2 type II secretion system protein E K02454 - - 0.000000002665 61.0
PYH2_k127_240654_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1070.0
PYH2_k127_240654_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 6.365e-260 814.0
PYH2_k127_240654_10 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000391 183.0
PYH2_k127_240654_11 NhaP-type Na H and K H - - - 0.000000000000000000000000000000000000000000005515 165.0
PYH2_k127_240654_12 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000000000025 165.0
PYH2_k127_240654_13 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000004121 164.0
PYH2_k127_240654_14 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000004037 159.0
PYH2_k127_240654_15 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000004195 153.0
PYH2_k127_240654_16 DRTGG domain - - - 0.0000000000000000000000000003962 117.0
PYH2_k127_240654_17 Sigma-54 dependent response regulator K07714 - - 0.000000000000000000000000007063 115.0
PYH2_k127_240654_18 DRTGG domain protein - - - 0.00000000000000000000000009205 111.0
PYH2_k127_240654_19 cyclic nucleotide-binding K21563 - - 0.00000006874 60.0
PYH2_k127_240654_2 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.282e-253 794.0
PYH2_k127_240654_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 4.729e-207 656.0
PYH2_k127_240654_4 Molybdopterin oxidoreductase Fe4S4 domain K00336,K05299,K22341 - 1.17.1.10,1.17.1.11,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 541.0
PYH2_k127_240654_5 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 503.0
PYH2_k127_240654_6 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 417.0
PYH2_k127_240654_7 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000002986 242.0
PYH2_k127_240654_8 PFAM PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000371 205.0
PYH2_k127_240654_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000004451 181.0
PYH2_k127_2432633_0 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009225 252.0
PYH2_k127_2432633_1 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000004353 179.0
PYH2_k127_2436423_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 532.0
PYH2_k127_2436423_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 445.0
PYH2_k127_2436423_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 333.0
PYH2_k127_2436423_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000009001 206.0
PYH2_k127_2488051_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 401.0
PYH2_k127_2488051_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 297.0
PYH2_k127_2488051_2 YtkA-like - - - 0.0000000000003197 75.0
PYH2_k127_2662684_0 cysteine synthase A K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 404.0
PYH2_k127_2662684_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 301.0
PYH2_k127_2672863_0 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001715 261.0
PYH2_k127_2672863_1 - - - - 0.00000000000000000000000000001253 123.0
PYH2_k127_2672863_2 Protein tyrosine serine phosphatase - - - 0.0000000000000000000001868 102.0
PYH2_k127_2672863_3 PFAM Isochorismatase - - - 0.00000000001265 64.0
PYH2_k127_268345_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 287.0
PYH2_k127_268345_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000028 250.0
PYH2_k127_268345_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000007354 146.0
PYH2_k127_269021_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 604.0
PYH2_k127_269021_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 314.0
PYH2_k127_27641_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 381.0
PYH2_k127_27641_1 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001943 248.0
PYH2_k127_27641_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000005796 222.0
PYH2_k127_27641_3 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000000313 181.0
PYH2_k127_27641_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000005428 123.0
PYH2_k127_27641_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000001171 51.0
PYH2_k127_2779618_0 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 348.0
PYH2_k127_2779618_1 PFAM flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000000003574 162.0
PYH2_k127_2779618_2 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000235 76.0
PYH2_k127_279926_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
PYH2_k127_279926_1 DNA polymerase III, epsilon subunit K02342,K03722 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 0.00000000000000000000000000000000000003051 145.0
PYH2_k127_279926_2 - - - - 0.00000000003329 65.0
PYH2_k127_2812195_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.058e-308 969.0
PYH2_k127_2812195_1 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.313e-281 877.0
PYH2_k127_2812195_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 471.0
PYH2_k127_2812195_3 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 308.0
PYH2_k127_2814825_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 454.0
PYH2_k127_2814825_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 292.0
PYH2_k127_2814825_2 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000002967 235.0
PYH2_k127_2814825_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03427 - 2.1.1.72 0.000000131 54.0
PYH2_k127_2853076_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 442.0
PYH2_k127_2853076_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 458.0
PYH2_k127_2853076_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 343.0
PYH2_k127_2853076_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 288.0
PYH2_k127_2853076_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000006998 242.0
PYH2_k127_2853076_5 Methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000000000000007918 208.0
PYH2_k127_2853076_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000001341 136.0
PYH2_k127_2853076_7 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000004087 111.0
PYH2_k127_2875261_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 342.0
PYH2_k127_2875261_1 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000008234 259.0
PYH2_k127_2875261_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000000000000000000001502 204.0
PYH2_k127_2875261_3 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000001374 164.0
PYH2_k127_2880215_0 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
PYH2_k127_2880215_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000009877 261.0
PYH2_k127_2880215_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000002707 241.0
PYH2_k127_2880215_3 AMP binding - - - 0.00000000000000000000000384 101.0
PYH2_k127_2884524_0 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
PYH2_k127_2884524_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 343.0
PYH2_k127_2884524_10 protein conserved in bacteria K09857 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0036405,GO:0036406,GO:0042597,GO:0042802,GO:0044425,GO:0044462,GO:0044464,GO:0071944,GO:0098552 - 0.0000006266 59.0
PYH2_k127_2884524_11 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000003752 49.0
PYH2_k127_2884524_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 314.0
PYH2_k127_2884524_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000051 265.0
PYH2_k127_2884524_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002548 256.0
PYH2_k127_2884524_5 Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000000000000000000000000000000000001259 243.0
PYH2_k127_2884524_6 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000004276 137.0
PYH2_k127_2884524_7 PFAM Mammalian cell entry related K02067 - - 0.00000000000000000000000001452 120.0
PYH2_k127_2884524_8 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000000000000000001755 104.0
PYH2_k127_2884524_9 antisigma factor binding K04749 - - 0.000000000000000002123 91.0
PYH2_k127_2889351_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1228.0
PYH2_k127_2889351_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 369.0
PYH2_k127_2889351_2 Belongs to the sirtuin family. Class K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000317 274.0
PYH2_k127_2889351_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000002353 231.0
PYH2_k127_2889351_4 MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000004522 208.0
PYH2_k127_2889351_5 TIGRFAM molybdenum cofactor synthesis - - - 0.000000000000000000000000000000000000000000000000000000006737 202.0
PYH2_k127_2889351_6 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000157 111.0
PYH2_k127_2889351_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000001688 93.0
PYH2_k127_2889351_9 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000003585 74.0
PYH2_k127_2896744_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 522.0
PYH2_k127_2896744_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 250.0
PYH2_k127_2896744_2 LUD domain K00782 - - 0.0000007588 51.0
PYH2_k127_290787_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 6.381e-194 639.0
PYH2_k127_290787_1 - - - - 0.000000000000000000000794 99.0
PYH2_k127_290787_2 O-methyltransferase activity - - - 0.00000000000000000003606 92.0
PYH2_k127_290787_4 Chromate transporter - - - 0.000007923 49.0
PYH2_k127_2959864_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 372.0
PYH2_k127_2959864_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007804 251.0
PYH2_k127_2959864_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000002762 61.0
PYH2_k127_2962364_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 4.766e-267 834.0
PYH2_k127_2962364_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 387.0
PYH2_k127_2962364_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 366.0
PYH2_k127_2962364_3 S-methyl-5'-thioadenosine phosphorylase K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000002199 263.0
PYH2_k127_2962364_4 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001112 262.0
PYH2_k127_2962364_5 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000001091 183.0
PYH2_k127_2962364_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000003097 168.0
PYH2_k127_2966909_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 431.0
PYH2_k127_2966909_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 335.0
PYH2_k127_2996152_0 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 300.0
PYH2_k127_2996152_1 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000002449 132.0
PYH2_k127_2996152_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000005013 83.0
PYH2_k127_2996152_3 Protein of unknown function (DUF2934) - - - 0.00003223 51.0
PYH2_k127_3002315_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
PYH2_k127_3002315_1 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000009828 178.0
PYH2_k127_3002315_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000002131 157.0
PYH2_k127_3002315_3 PFAM HNH endonuclease K07451 - - 0.00000000000000000000000000000000002051 137.0
PYH2_k127_3002315_4 Protein of unknown function (DUF507) - - - 0.000000000000000000000000000753 114.0
PYH2_k127_3002315_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000009943 113.0
PYH2_k127_3002315_6 Protein of unknown function (DUF507) - - - 0.000000000000000000000001158 106.0
PYH2_k127_3002315_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000002213 61.0
PYH2_k127_3002315_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000004084 53.0
PYH2_k127_3020236_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.952e-253 794.0
PYH2_k127_3020236_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 541.0
PYH2_k127_3020236_2 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 519.0
PYH2_k127_3020236_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 512.0
PYH2_k127_3020236_4 NIL - - - 0.0000006066 51.0
PYH2_k127_3067219_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 594.0
PYH2_k127_3067219_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 387.0
PYH2_k127_3067219_2 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 368.0
PYH2_k127_3067219_3 iron-sulfur cluster assembly - - - 0.00000000000000000000000003649 109.0
PYH2_k127_3085170_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000089 273.0
PYH2_k127_3085170_1 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000001055 92.0
PYH2_k127_3092067_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 361.0
PYH2_k127_3135340_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.584e-253 788.0
PYH2_k127_3135340_1 AMP binding - - - 0.00000000000000000000000000001021 123.0
PYH2_k127_3254165_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 7.335e-239 750.0
PYH2_k127_3254165_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 530.0
PYH2_k127_3254165_10 Cytochrome c1 - - - 0.000000000000000002097 88.0
PYH2_k127_3254165_2 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 428.0
PYH2_k127_3254165_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 420.0
PYH2_k127_3254165_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 313.0
PYH2_k127_3254165_5 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
PYH2_k127_3254165_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000002443 231.0
PYH2_k127_3254165_7 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000002541 193.0
PYH2_k127_3254165_8 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000959 162.0
PYH2_k127_3254165_9 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000000003544 123.0
PYH2_k127_3314951_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 552.0
PYH2_k127_3314951_2 Domain of unknown function (DUF1844) - - - 0.000000000005037 70.0
PYH2_k127_3319753_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 401.0
PYH2_k127_3319753_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 298.0
PYH2_k127_3319753_2 PFAM SCP-like extracellular - - - 0.0000000000000000000000000001075 123.0
PYH2_k127_334271_0 Polysulphide reductase, NrfD - - - 9.628e-203 639.0
PYH2_k127_334271_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 427.0
PYH2_k127_334271_2 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000001807 227.0
PYH2_k127_334271_3 Cytochrome c7 and related cytochrome c - - - 0.00000001694 64.0
PYH2_k127_3380478_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 462.0
PYH2_k127_3380478_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 291.0
PYH2_k127_3380478_2 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007538 288.0
PYH2_k127_3384677_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 419.0
PYH2_k127_3384677_1 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 305.0
PYH2_k127_3384677_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003283 266.0
PYH2_k127_3384677_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000006244 244.0
PYH2_k127_3384677_4 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000002191 126.0
PYH2_k127_3384677_5 Uncharacterized protein family, UPF0114 - - - 0.0000003203 51.0
PYH2_k127_3399422_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 480.0
PYH2_k127_3399422_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000219 244.0
PYH2_k127_3415274_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 606.0
PYH2_k127_3415274_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 315.0
PYH2_k127_3415274_2 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008757 264.0
PYH2_k127_3415274_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000001024 140.0
PYH2_k127_3415274_4 Major facilitator superfamily K08224 - - 0.00000000000000000000002184 104.0
PYH2_k127_3419073_0 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000001794 113.0
PYH2_k127_3419073_1 aspartic-type endopeptidase activity K06985 - - 0.00000009772 61.0
PYH2_k127_3433830_0 Methyltransferase, chemotaxis proteins K13924 - 2.1.1.80,3.1.1.61 8.251e-277 873.0
PYH2_k127_3442254_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 421.0
PYH2_k127_3442254_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000003473 171.0
PYH2_k127_3479157_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
PYH2_k127_3479157_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000001608 189.0
PYH2_k127_3479157_2 - - - - 0.000000000000000000000000000000000002749 143.0
PYH2_k127_3479157_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000001317 122.0
PYH2_k127_35131_0 Beta-Casp domain K07576 - - 1.675e-197 625.0
PYH2_k127_35131_1 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 467.0
PYH2_k127_35131_2 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 437.0
PYH2_k127_35131_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002243 248.0
PYH2_k127_35131_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000001421 246.0
PYH2_k127_35131_5 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.0000000000000000000000000000000006096 132.0
PYH2_k127_35131_6 Antitoxin component of a toxin-antitoxin (TA) module K08591,K19159 - 2.3.1.15 0.00000000000000000000000000000103 122.0
PYH2_k127_35131_7 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.000000000000000000009217 99.0
PYH2_k127_35131_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000002438 90.0
PYH2_k127_35131_9 DoxX K15977 - - 0.00000000003117 63.0
PYH2_k127_3583415_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.252e-208 668.0
PYH2_k127_3583415_1 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 314.0
PYH2_k127_3583415_2 HNH nucleases - - - 0.00000000000000000000000000000000000000000000009493 170.0
PYH2_k127_3583415_3 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000004659 119.0
PYH2_k127_3583415_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000006308 52.0
PYH2_k127_3740985_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 285.0
PYH2_k127_3740985_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.0000000000000000000000000000000000000000000000000000000001968 221.0
PYH2_k127_3740985_2 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000001856 175.0
PYH2_k127_3740985_3 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.000000000000000000000000000000000000000004598 159.0
PYH2_k127_3740985_4 PFAM Nickel uptake substrate-specific transmembrane region K10094 - - 0.0000000000000000000000000000000003607 148.0
PYH2_k127_3740985_5 Transcriptional regulator K11921,K19338 - - 0.00001512 48.0
PYH2_k127_3748184_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1541.0
PYH2_k127_3748184_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 489.0
PYH2_k127_3748184_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 389.0
PYH2_k127_3748184_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 329.0
PYH2_k127_3748184_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 295.0
PYH2_k127_3748184_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000001257 248.0
PYH2_k127_3748184_6 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000002755 195.0
PYH2_k127_3748184_7 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000002106 167.0
PYH2_k127_3748184_8 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000006824 132.0
PYH2_k127_3748184_9 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000009833 96.0
PYH2_k127_3752386_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 314.0
PYH2_k127_3752386_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 319.0
PYH2_k127_3752386_2 HTH domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
PYH2_k127_3752386_3 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000007311 196.0
PYH2_k127_3752386_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000006271 181.0
PYH2_k127_3752386_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000001581 171.0
PYH2_k127_3752702_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1154.0
PYH2_k127_3752702_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
PYH2_k127_3752702_2 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000357 214.0
PYH2_k127_3752702_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000001176 177.0
PYH2_k127_3752702_4 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000002935 144.0
PYH2_k127_3752702_5 PFAM membrane protein of K08972 - - 0.0000000000000000000000002575 111.0
PYH2_k127_37579_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 540.0
PYH2_k127_37579_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 503.0
PYH2_k127_37579_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 481.0
PYH2_k127_3787005_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 443.0
PYH2_k127_3787005_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 409.0
PYH2_k127_3787005_2 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000003749 198.0
PYH2_k127_3787005_3 EthD domain - - - 0.000000000000000000000000000000000000000000000000005612 183.0
PYH2_k127_3787005_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000001318 161.0
PYH2_k127_3787005_5 nuclease activity - - - 0.00000000000000000000000000000000000000001236 158.0
PYH2_k127_3823452_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.381e-319 982.0
PYH2_k127_3823452_1 glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 372.0
PYH2_k127_3823452_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000001847 213.0
PYH2_k127_3823452_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000001407 193.0
PYH2_k127_3824898_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 369.0
PYH2_k127_3824898_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000005693 145.0
PYH2_k127_3824898_2 Histidine kinase - - - 0.000000000000000000000000005891 130.0
PYH2_k127_3824898_3 KaiB K08481 - - 0.0000000000000128 73.0
PYH2_k127_3844249_0 PFAM magnesium chelatase ChlI subunit K07391 - - 8.078e-210 663.0
PYH2_k127_3844249_1 Fructose-bisphosphate aldolase class-II - - - 2.366e-198 627.0
PYH2_k127_3844249_2 radical SAM protein K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 291.0
PYH2_k127_3844249_3 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000002931 166.0
PYH2_k127_3846645_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1256.0
PYH2_k127_3846645_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 592.0
PYH2_k127_3846645_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 318.0
PYH2_k127_3846645_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001004 265.0
PYH2_k127_3846645_4 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000000000000000000000003231 213.0
PYH2_k127_3846645_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000008858 171.0
PYH2_k127_3846645_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000134 163.0
PYH2_k127_3846645_7 NADPH-quinone reductase (modulator of drug activity B) - - - 0.00000000000000000000000244 107.0
PYH2_k127_3879396_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 483.0
PYH2_k127_3879396_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 306.0
PYH2_k127_3879396_2 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000001316 163.0
PYH2_k127_3879396_3 - - - - 0.0000000000000000000000000000000001196 143.0
PYH2_k127_3879396_4 - - - - 0.0000000000000000000000000000007668 131.0
PYH2_k127_3882020_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 575.0
PYH2_k127_3882020_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 580.0
PYH2_k127_3882020_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000004747 172.0
PYH2_k127_3882020_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 496.0
PYH2_k127_3882020_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 391.0
PYH2_k127_3882020_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 367.0
PYH2_k127_3882020_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 365.0
PYH2_k127_3882020_6 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 340.0
PYH2_k127_3882020_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 295.0
PYH2_k127_3882020_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002327 247.0
PYH2_k127_3882020_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000008131 245.0
PYH2_k127_3899199_0 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009668 263.0
PYH2_k127_3899199_1 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000003108 235.0
PYH2_k127_3899199_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000005936 202.0
PYH2_k127_3917477_0 Aminotransferase class-III K01845 - 5.4.3.8 7.596e-210 659.0
PYH2_k127_3917477_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 580.0
PYH2_k127_3917477_2 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 373.0
PYH2_k127_3917477_3 PFAM ABC transporter related K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
PYH2_k127_3917477_4 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000759 269.0
PYH2_k127_3917477_5 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000005773 187.0
PYH2_k127_3917477_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000002409 65.0
PYH2_k127_4013184_0 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 477.0
PYH2_k127_4013184_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 439.0
PYH2_k127_4013184_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 332.0
PYH2_k127_4013184_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000007817 197.0
PYH2_k127_4013184_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000001536 142.0
PYH2_k127_4058959_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 608.0
PYH2_k127_4058959_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000002657 52.0
PYH2_k127_4058959_3 PFAM GCN5-related N-acetyltransferase - - - 0.0002152 45.0
PYH2_k127_4068089_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 4.973e-214 676.0
PYH2_k127_4068089_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 364.0
PYH2_k127_4068089_2 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001295 284.0
PYH2_k127_4068089_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000007008 196.0
PYH2_k127_4068089_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000814 91.0
PYH2_k127_407481_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 2.974e-210 659.0
PYH2_k127_407481_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 414.0
PYH2_k127_407481_2 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000002771 190.0
PYH2_k127_407481_3 - - - - 0.000000000000000000000000000000000000000000000000417 181.0
PYH2_k127_4133150_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.244e-205 645.0
PYH2_k127_4133150_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005181 282.0
PYH2_k127_4133150_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000001254 65.0
PYH2_k127_4138774_0 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 464.0
PYH2_k127_4138774_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 342.0
PYH2_k127_4138774_2 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.000002998 49.0
PYH2_k127_4142285_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 588.0
PYH2_k127_4142285_1 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 408.0
PYH2_k127_4142285_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000004499 226.0
PYH2_k127_4142285_3 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000000000416 119.0
PYH2_k127_4159919_0 PD-(D/E)XK nuclease superfamily - - - 2.68e-241 780.0
PYH2_k127_4159919_1 Belongs to the helicase family. UvrD subfamily - - - 2.624e-205 672.0
PYH2_k127_4159919_2 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001671 277.0
PYH2_k127_4159919_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006565 256.0
PYH2_k127_4159919_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000009767 216.0
PYH2_k127_4159919_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000965 165.0
PYH2_k127_4175932_1 sequence-specific DNA binding - - - 0.0001036 50.0
PYH2_k127_4180308_0 HI0933-like protein K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 411.0
PYH2_k127_4180308_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 323.0
PYH2_k127_4180308_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000104 261.0
PYH2_k127_4210843_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 572.0
PYH2_k127_4210843_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 399.0
PYH2_k127_4210843_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 344.0
PYH2_k127_4210843_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004401 275.0
PYH2_k127_4211805_0 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 7.563e-206 652.0
PYH2_k127_4211805_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002204 273.0
PYH2_k127_4211805_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
PYH2_k127_4211805_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000001197 145.0
PYH2_k127_4211805_4 - - - - 0.0002999 44.0
PYH2_k127_4214758_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 2.993e-196 618.0
PYH2_k127_4214758_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 522.0
PYH2_k127_4214758_2 response regulator K07664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 344.0
PYH2_k127_4214758_3 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000000000000007524 213.0
PYH2_k127_4214758_4 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000000000000000000000000003482 179.0
PYH2_k127_4214758_5 PFAM DsrE DsrF-like family - - - 0.0000000000000000000000000000000000000001614 155.0
PYH2_k127_4214758_6 anaerobic respiration - - - 0.000000000000000000000002934 115.0
PYH2_k127_4214758_7 YMGG-like Gly-zipper - - - 0.000000000000000000008414 95.0
PYH2_k127_4230864_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 342.0
PYH2_k127_4230864_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000003499 186.0
PYH2_k127_4230864_4 protein secretion K03116,K03117 - - 0.000000000000003182 80.0
PYH2_k127_4257838_0 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 260.0
PYH2_k127_4257838_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001999 259.0
PYH2_k127_4257838_2 - - - - 0.00000000000000000000000000000000000001373 148.0
PYH2_k127_4257838_3 - - - - 0.0000000000000000000000000000000000001373 148.0
PYH2_k127_426029_0 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000403 209.0
PYH2_k127_426029_1 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000001865 133.0
PYH2_k127_426029_2 - - - - 0.000000000000000000000000001201 114.0
PYH2_k127_426029_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000001329 117.0
PYH2_k127_430737_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 546.0
PYH2_k127_430737_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 374.0
PYH2_k127_430737_10 - - - - 0.0003986 51.0
PYH2_k127_430737_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000002963 182.0
PYH2_k127_430737_3 general secretion pathway protein K02461 - - 0.0000000000105 78.0
PYH2_k127_430737_4 Type II transport protein GspH - - - 0.000000002234 66.0
PYH2_k127_430737_5 type IV pilus modification protein PilV K02458 - - 0.00000001421 61.0
PYH2_k127_430737_6 Type II secretion system (T2SS), protein M subtype b - - - 0.000000059 61.0
PYH2_k127_430737_7 Prokaryotic N-terminal methylation motif K02459 - - 0.000000099 62.0
PYH2_k127_430737_8 PFAM Fimbrial assembly family protein K02461,K02662,K02663 - - 0.00003666 56.0
PYH2_k127_430737_9 Acetyltransferase (GNAT) domain - - - 0.0003269 51.0
PYH2_k127_4322436_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.442e-211 671.0
PYH2_k127_4322436_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 404.0
PYH2_k127_4322436_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 332.0
PYH2_k127_4322436_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 310.0
PYH2_k127_4322436_4 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
PYH2_k127_4322436_5 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000003646 175.0
PYH2_k127_4322436_6 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000001507 100.0
PYH2_k127_4324118_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 557.0
PYH2_k127_4324118_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000141 220.0
PYH2_k127_4324118_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001108 205.0
PYH2_k127_4324118_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000004874 148.0
PYH2_k127_4324118_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000317 65.0
PYH2_k127_434373_0 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 524.0
PYH2_k127_434373_1 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 476.0
PYH2_k127_434373_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000003622 173.0
PYH2_k127_435029_0 Belongs to the CarB family K01955 - 6.3.5.5 1.666e-285 897.0
PYH2_k127_435029_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 544.0
PYH2_k127_4350443_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000007976 232.0
PYH2_k127_4350443_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000005681 221.0
PYH2_k127_4350443_2 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000008221 181.0
PYH2_k127_4350443_3 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000000000000000000009825 177.0
PYH2_k127_4350443_4 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000003081 82.0
PYH2_k127_4350443_5 - - - - 0.0000000007609 63.0
PYH2_k127_4350443_6 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.000000308 53.0
PYH2_k127_4350443_7 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.000000738 58.0
PYH2_k127_4385785_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1204.0
PYH2_k127_4385785_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
PYH2_k127_4385785_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000001519 220.0
PYH2_k127_4385785_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000002782 89.0
PYH2_k127_4385785_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000006331 82.0
PYH2_k127_4422037_0 Glycosyl hydrolase family 57 - - - 2.755e-232 741.0
PYH2_k127_4422037_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 607.0
PYH2_k127_4422037_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 475.0
PYH2_k127_4422037_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000001683 182.0
PYH2_k127_4422037_4 cell cycle K05589,K12065,K13052 - - 0.000000000000000008435 87.0
PYH2_k127_4466640_0 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000156 244.0
PYH2_k127_4466640_1 regulation of ruffle assembly - - - 0.000000000000000000000000000000000000000000000000000000000139 213.0
PYH2_k127_4466640_2 Poly-gamma-glutamate hydrolase - - - 0.0000000000000000000000000000000000000001461 158.0
PYH2_k127_4466640_3 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000002639 109.0
PYH2_k127_4466640_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000003184 104.0
PYH2_k127_4468481_0 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 376.0
PYH2_k127_4490444_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1101.0
PYH2_k127_4490444_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 391.0
PYH2_k127_4490444_2 Cyclophilin-like K09143 - - 0.000000000000000000000000000000001918 130.0
PYH2_k127_4490444_3 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000002442 138.0
PYH2_k127_4499334_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 373.0
PYH2_k127_4499334_1 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000257 249.0
PYH2_k127_4510939_0 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 344.0
PYH2_k127_4510939_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 294.0
PYH2_k127_4510939_2 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.00000000000000000000000000000000000000000000000000000001179 207.0
PYH2_k127_4533921_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.917e-277 859.0
PYH2_k127_4533921_1 B3/4 domain K01890 - 6.1.1.20 3.071e-211 676.0
PYH2_k127_4533921_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 470.0
PYH2_k127_4533921_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000007006 176.0
PYH2_k127_4533921_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000002156 169.0
PYH2_k127_4533921_5 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000000009118 95.0
PYH2_k127_4533921_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000006238 94.0
PYH2_k127_4534344_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1320.0
PYH2_k127_4534344_1 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 347.0
PYH2_k127_4534344_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003793 266.0
PYH2_k127_455746_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.728e-268 842.0
PYH2_k127_455746_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 306.0
PYH2_k127_455746_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0003632 54.0
PYH2_k127_455746_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004242 274.0
PYH2_k127_455746_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
PYH2_k127_455746_4 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 260.0
PYH2_k127_455746_5 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002835 244.0
PYH2_k127_455746_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000002105 241.0
PYH2_k127_455746_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000241 205.0
PYH2_k127_455746_8 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000006246 104.0
PYH2_k127_455746_9 Regulatory protein, FmdB family - - - 0.000000000000273 70.0
PYH2_k127_4569624_0 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 2.907e-223 700.0
PYH2_k127_4569624_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05588 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 428.0
PYH2_k127_4569624_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 290.0
PYH2_k127_4569624_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
PYH2_k127_4569624_4 spore germination K03605 - - 0.00006763 47.0
PYH2_k127_46222_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 451.0
PYH2_k127_46222_1 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 406.0
PYH2_k127_46222_2 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000005254 240.0
PYH2_k127_46222_3 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000000000006585 177.0
PYH2_k127_46222_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000002278 92.0
PYH2_k127_46222_5 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000003558 74.0
PYH2_k127_4674719_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 5.43e-276 861.0
PYH2_k127_4674719_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 543.0
PYH2_k127_4674719_10 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.000000000000000000000000000000002942 132.0
PYH2_k127_4674719_11 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000001239 124.0
PYH2_k127_4674719_12 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000000000001957 124.0
PYH2_k127_4674719_13 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000004803 112.0
PYH2_k127_4674719_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000002906 70.0
PYH2_k127_4674719_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 463.0
PYH2_k127_4674719_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 357.0
PYH2_k127_4674719_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 344.0
PYH2_k127_4674719_5 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 324.0
PYH2_k127_4674719_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 319.0
PYH2_k127_4674719_7 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 293.0
PYH2_k127_4674719_8 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000000007267 213.0
PYH2_k127_4674719_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000004948 198.0
PYH2_k127_4678527_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 438.0
PYH2_k127_4678527_1 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 365.0
PYH2_k127_4678527_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
PYH2_k127_4678527_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000002377 127.0
PYH2_k127_4678527_4 Zinc finger cdgsh-type domain protein - - - 0.000000000000000000000000002759 112.0
PYH2_k127_4678527_5 Universal stress protein family - - - 0.000000000000000001902 96.0
PYH2_k127_4678527_6 Bacterial regulatory helix-turn-helix proteins, AraC family K10778 - 2.1.1.63 0.000001356 51.0
PYH2_k127_4682918_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.992e-307 953.0
PYH2_k127_4682918_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005535 282.0
PYH2_k127_4682918_2 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
PYH2_k127_4682918_3 response to copper ion - - - 0.00000000000000000000000006941 119.0
PYH2_k127_4682918_4 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000007158 74.0
PYH2_k127_4682918_5 copper chaperone K07213 - - 0.0004646 47.0
PYH2_k127_4693978_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.361e-291 899.0
PYH2_k127_4693978_1 proteolysis K07059 - - 0.0000000000000000000000000000000000000000000000000000000001394 209.0
PYH2_k127_4693978_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000003339 144.0
PYH2_k127_4693978_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000002281 130.0
PYH2_k127_4703606_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.793e-208 653.0
PYH2_k127_4703606_1 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000003709 197.0
PYH2_k127_4703606_2 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000558 172.0
PYH2_k127_4703606_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000005729 149.0
PYH2_k127_4716583_0 Bacterial regulatory protein, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 385.0
PYH2_k127_4716583_1 type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 335.0
PYH2_k127_4716583_2 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.000000000000006837 76.0
PYH2_k127_4723662_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007474 274.0
PYH2_k127_4723662_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001213 256.0
PYH2_k127_4723662_2 response regulator - - - 0.000000000000000000000000002712 129.0
PYH2_k127_4723662_3 denitrification pathway - - - 0.0000000000000000000123 94.0
PYH2_k127_4738530_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 498.0
PYH2_k127_4738530_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001969 261.0
PYH2_k127_4738530_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000002249 146.0
PYH2_k127_4738530_3 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32 0.000000000000000000000000000114 117.0
PYH2_k127_4754734_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.48e-285 888.0
PYH2_k127_4755734_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.528e-268 848.0
PYH2_k127_4755734_1 Ftsk_gamma K03466 - - 1.032e-220 706.0
PYH2_k127_4755734_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.51e-208 662.0
PYH2_k127_4755734_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 299.0
PYH2_k127_4755734_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001472 271.0
PYH2_k127_4755734_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000006887 224.0
PYH2_k127_4755734_6 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000000002726 173.0
PYH2_k127_4755734_7 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000002276 149.0
PYH2_k127_4767510_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 6.323e-199 625.0
PYH2_k127_4767510_1 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 302.0
PYH2_k127_4767510_2 - - - - 0.00000000000000000000783 94.0
PYH2_k127_4783947_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 556.0
PYH2_k127_4783947_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001016 246.0
PYH2_k127_4783947_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000002407 184.0
PYH2_k127_4812795_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 440.0
PYH2_k127_4812795_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 316.0
PYH2_k127_4812795_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002509 281.0
PYH2_k127_4812795_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000668 276.0
PYH2_k127_4812795_4 lyase activity - - - 0.000000000000000000000000000000000000000000000000002799 202.0
PYH2_k127_4812795_5 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000004759 178.0
PYH2_k127_4812795_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000001958 131.0
PYH2_k127_4812795_7 Plasmid stabilization system - - - 0.00000000000000000000000000004841 118.0
PYH2_k127_4827950_0 PFAM Type II secretion system protein E K02652 - - 5.277e-201 642.0
PYH2_k127_4827950_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 310.0
PYH2_k127_4827950_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000007713 141.0
PYH2_k127_4827950_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000002026 125.0
PYH2_k127_4827950_4 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000003837 118.0
PYH2_k127_4827950_5 Pilus assembly protein, PilP K02665 - - 0.00000000000000001313 89.0
PYH2_k127_4827950_6 Secretin and TonB N terminus short domain K02666 - - 0.0000007156 60.0
PYH2_k127_4833352_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.286e-202 637.0
PYH2_k127_4833352_1 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 603.0
PYH2_k127_4833352_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00002308 50.0
PYH2_k127_4843098_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 561.0
PYH2_k127_4843098_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 319.0
PYH2_k127_4843098_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 323.0
PYH2_k127_4843098_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
PYH2_k127_4843098_4 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009639 276.0
PYH2_k127_4843098_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000004942 215.0
PYH2_k127_4843098_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000002894 198.0
PYH2_k127_4843098_7 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000001177 132.0
PYH2_k127_4843098_8 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000009612 115.0
PYH2_k127_4843098_9 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000002549 113.0
PYH2_k127_48495_0 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 405.0
PYH2_k127_48495_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001525 258.0
PYH2_k127_48495_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000003149 189.0
PYH2_k127_48495_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000001296 136.0
PYH2_k127_48495_4 Stringent starvation protein B K09985 - - 0.0000000000000000000000002524 112.0
PYH2_k127_4854819_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 370.0
PYH2_k127_4854819_1 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000865 223.0
PYH2_k127_4854819_2 Belongs to the ompA family K03640 - - 0.0000000000002497 70.0
PYH2_k127_4859188_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.075e-233 740.0
PYH2_k127_4859188_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 472.0
PYH2_k127_4859188_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000002592 147.0
PYH2_k127_486188_0 Protein of unknown function (DUF3373) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 258.0
PYH2_k127_486188_1 Protein of unknown function (DUF3373) - - - 0.0000000000000000000000000000000000000000000000000000000000000001902 230.0
PYH2_k127_486188_2 peroxiredoxin activity - - - 0.00000000000000000000008975 104.0
PYH2_k127_4873975_0 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 467.0
PYH2_k127_4873975_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 313.0
PYH2_k127_4873975_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000007137 128.0
PYH2_k127_4873975_3 - - - - 0.000000000001007 73.0
PYH2_k127_4873975_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000244 60.0
PYH2_k127_4873975_7 - - - - 0.000006007 51.0
PYH2_k127_4874900_0 Nitroreductase - - - 1.067e-201 640.0
PYH2_k127_4922861_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 527.0
PYH2_k127_4922861_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 503.0
PYH2_k127_4922861_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 354.0
PYH2_k127_4922861_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003246 240.0
PYH2_k127_4924836_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 491.0
PYH2_k127_4924836_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 353.0
PYH2_k127_4924836_2 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 352.0
PYH2_k127_4924836_3 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000002446 177.0
PYH2_k127_4924836_4 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000002088 151.0
PYH2_k127_4924836_5 Protein of unknown function DUF72 - - - 0.00000000000000000004539 94.0
PYH2_k127_4927560_0 RNA recognition motif - - - 0.00000000000000000000000000003888 119.0
PYH2_k127_4927560_1 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000003974 73.0
PYH2_k127_4935525_0 Protein conserved in bacteria - - - 1.675e-249 796.0
PYH2_k127_4935525_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 600.0
PYH2_k127_4935525_2 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 297.0
PYH2_k127_4935525_3 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 260.0
PYH2_k127_4935525_4 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000006485 201.0
PYH2_k127_4935525_5 radical SAM K06871 - - 0.00000000000000000000000002966 111.0
PYH2_k127_4935525_6 snoRNA binding - - - 0.0000398 49.0
PYH2_k127_4940189_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 398.0
PYH2_k127_4940189_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 269.0
PYH2_k127_4940189_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000006091 193.0
PYH2_k127_4945969_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 380.0
PYH2_k127_4945969_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 373.0
PYH2_k127_4945969_10 Thiamine-binding protein - - - 0.0000000000000000000000000000000002552 134.0
PYH2_k127_4945969_11 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000003657 118.0
PYH2_k127_4945969_12 - - - - 0.00000000000000000000001575 102.0
PYH2_k127_4945969_13 methyltransferase activity - - - 0.0000000000000000000007112 97.0
PYH2_k127_4945969_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 374.0
PYH2_k127_4945969_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002896 276.0
PYH2_k127_4945969_4 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000006186 245.0
PYH2_k127_4945969_5 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000001165 235.0
PYH2_k127_4945969_6 PFAM Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000001868 212.0
PYH2_k127_4945969_7 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000244 158.0
PYH2_k127_4945969_8 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000002249 146.0
PYH2_k127_4945969_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000002562 138.0
PYH2_k127_4972001_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 292.0
PYH2_k127_4972001_1 diguanylate cyclase K14986 - 2.7.13.3 0.0000000000000000000000000000004642 139.0
PYH2_k127_4988988_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 347.0
PYH2_k127_4988988_1 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 295.0
PYH2_k127_4988988_2 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000001084 223.0
PYH2_k127_4988988_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
PYH2_k127_4988988_4 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000003379 196.0
PYH2_k127_4996458_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 580.0
PYH2_k127_4996458_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 329.0
PYH2_k127_4996458_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
PYH2_k127_4996458_3 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000002094 235.0
PYH2_k127_4996568_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 503.0
PYH2_k127_4996568_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 463.0
PYH2_k127_4996568_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 406.0
PYH2_k127_4996568_3 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 293.0
PYH2_k127_4996568_4 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 258.0
PYH2_k127_4996568_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000000002845 179.0
PYH2_k127_5006796_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 566.0
PYH2_k127_5006796_1 PFAM SNARE associated Golgi protein - - - 0.00000001042 58.0
PYH2_k127_5103018_0 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 429.0
PYH2_k127_5103018_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000006717 192.0
PYH2_k127_5103018_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000001864 185.0
PYH2_k127_5108403_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1033.0
PYH2_k127_5108403_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 318.0
PYH2_k127_5108403_2 - - - - 0.0000000000000000000000000000000000001799 152.0
PYH2_k127_5108403_3 Histidine kinase K02491 - 2.7.13.3 0.000000000000000000003643 109.0
PYH2_k127_5184141_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 460.0
PYH2_k127_5184141_1 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 349.0
PYH2_k127_5184141_2 Universal stress protein - - - 0.0000000000000000000000000000000000000000001151 163.0
PYH2_k127_5184141_3 Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000004333 120.0
PYH2_k127_5184141_4 Winged helix-turn helix - - - 0.00000000000000000009854 94.0
PYH2_k127_528608_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.521e-233 731.0
PYH2_k127_528608_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.535e-219 690.0
PYH2_k127_528608_10 intermediate-associated protein 30 - - - 0.000000000000000000000000000000000000000003053 160.0
PYH2_k127_528608_11 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000001554 93.0
PYH2_k127_528608_12 phosphorelay sensor kinase activity K10909 - 2.7.13.3 0.00000000002954 75.0
PYH2_k127_528608_2 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 499.0
PYH2_k127_528608_3 threonine K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 359.0
PYH2_k127_528608_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 299.0
PYH2_k127_528608_5 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005129 280.0
PYH2_k127_528608_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004469 250.0
PYH2_k127_528608_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000006412 229.0
PYH2_k127_528608_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004926 218.0
PYH2_k127_528608_9 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000006439 170.0
PYH2_k127_5314384_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 515.0
PYH2_k127_5314384_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000005457 241.0
PYH2_k127_5314384_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000156 162.0
PYH2_k127_5314384_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000004656 128.0
PYH2_k127_5314384_4 nucleotidyltransferase activity K07075 - - 0.000000000000000000000002101 109.0
PYH2_k127_5314384_5 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000002629 88.0
PYH2_k127_537731_0 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 387.0
PYH2_k127_537731_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
PYH2_k127_537731_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000008315 132.0
PYH2_k127_537731_3 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0000000000000000000000000003305 115.0
PYH2_k127_5386245_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 565.0
PYH2_k127_5386245_1 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 560.0
PYH2_k127_5386245_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 463.0
PYH2_k127_5386245_3 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 415.0
PYH2_k127_5386245_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 359.0
PYH2_k127_5386245_5 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000005087 186.0
PYH2_k127_5386245_6 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000001271 149.0
PYH2_k127_5386245_7 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000004186 145.0
PYH2_k127_5386245_8 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001047 93.0
PYH2_k127_5386245_9 - - - - 0.000000000005136 66.0
PYH2_k127_5470655_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 592.0
PYH2_k127_5470655_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 549.0
PYH2_k127_5470655_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 355.0
PYH2_k127_5470655_3 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003113 288.0
PYH2_k127_5470655_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004829 243.0
PYH2_k127_5470655_5 Protein of unknown function (DUF1284) K09706 - - 0.000000000000000000000000000000000000009012 149.0
PYH2_k127_5470655_6 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000002728 145.0
PYH2_k127_5470655_8 Helix-turn-helix domain - - - 0.0000000000000000000000000000005687 133.0
PYH2_k127_5470655_9 PFAM transposase IS3 IS911 family protein K07497 - - 0.0000000000009891 71.0
PYH2_k127_5471111_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 471.0
PYH2_k127_5471111_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 360.0
PYH2_k127_5471111_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
PYH2_k127_5471111_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000001288 182.0
PYH2_k127_5503598_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 331.0
PYH2_k127_5503598_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000005832 196.0
PYH2_k127_5503598_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000005025 184.0
PYH2_k127_5503598_3 nickel cation binding K04651,K19640 - - 0.0000000000000000000000000000005374 127.0
PYH2_k127_5503598_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000002262 120.0
PYH2_k127_5503598_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000003905 99.0
PYH2_k127_5533170_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.599e-265 836.0
PYH2_k127_55341_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 8.926e-199 627.0
PYH2_k127_55341_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 392.0
PYH2_k127_55341_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000001987 203.0
PYH2_k127_55341_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
PYH2_k127_55341_4 - - - - 0.00000000000000000000000000000000000000000000000000001097 199.0
PYH2_k127_55341_5 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000001016 168.0
PYH2_k127_5553147_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 292.0
PYH2_k127_5553147_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001104 280.0
PYH2_k127_5553147_2 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000001617 57.0
PYH2_k127_5596895_0 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001112 214.0
PYH2_k127_5596895_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000009224 201.0
PYH2_k127_5596895_2 Bacterial regulatory protein, Fis family K07712 - - 0.0000000000000000000000000000000002012 139.0
PYH2_k127_5640662_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 602.0
PYH2_k127_5640662_1 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
PYH2_k127_5640662_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000001843 213.0
PYH2_k127_5640662_3 Histidine kinase - - - 0.00000000000000000000000005154 123.0
PYH2_k127_5647391_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 561.0
PYH2_k127_5647391_1 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 346.0
PYH2_k127_5647391_2 Transporter associated domain K03699 - - 0.00000000005894 65.0
PYH2_k127_5654211_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 536.0
PYH2_k127_5654211_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 475.0
PYH2_k127_5654211_2 Transposase IS200 like - - - 0.00000000000000000000000003202 111.0
PYH2_k127_5654211_3 - - - - 0.00000419 49.0
PYH2_k127_5674500_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 4.614e-281 872.0
PYH2_k127_5674500_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.619e-245 770.0
PYH2_k127_5680751_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 4.853e-215 677.0
PYH2_k127_5680751_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.381e-203 644.0
PYH2_k127_5680751_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 494.0
PYH2_k127_5680751_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000008147 207.0
PYH2_k127_5680751_4 amino acid-binding ACT - - - 0.00000000000000000000000000000000000000000000000000000206 194.0
PYH2_k127_5680751_5 - - - - 0.000000000000000000000000000000000000001921 152.0
PYH2_k127_5698924_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.798e-239 744.0
PYH2_k127_5698924_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.336e-219 701.0
PYH2_k127_5698924_10 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000000000003815 184.0
PYH2_k127_5698924_11 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000004908 170.0
PYH2_k127_5698924_12 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000000002909 145.0
PYH2_k127_5698924_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 514.0
PYH2_k127_5698924_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 398.0
PYH2_k127_5698924_4 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 321.0
PYH2_k127_5698924_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 316.0
PYH2_k127_5698924_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 264.0
PYH2_k127_5698924_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000001592 211.0
PYH2_k127_5698924_8 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000001874 192.0
PYH2_k127_5698924_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000001324 189.0
PYH2_k127_5737460_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 467.0
PYH2_k127_5747857_0 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 449.0
PYH2_k127_5747857_1 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 304.0
PYH2_k127_575482_0 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 455.0
PYH2_k127_575482_1 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000001227 188.0
PYH2_k127_575482_2 - - - - 0.00000000000000000000000000000000000000000002378 165.0
PYH2_k127_5800199_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.013e-257 804.0
PYH2_k127_5800199_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 543.0
PYH2_k127_5800199_10 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000001235 149.0
PYH2_k127_5800199_11 chemotaxis K03408 - - 0.00000000000000000000000000000000000005251 147.0
PYH2_k127_5800199_2 Two component signalling adaptor domain K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 544.0
PYH2_k127_5800199_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 385.0
PYH2_k127_5800199_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 345.0
PYH2_k127_5800199_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 306.0
PYH2_k127_5800199_6 Histidine kinase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008318 265.0
PYH2_k127_5800199_7 Histidine kinase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001863 263.0
PYH2_k127_5800199_8 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000004444 234.0
PYH2_k127_5800199_9 response regulator K02658 - - 0.000000000000000000000000000000000000000000000000000000001094 221.0
PYH2_k127_5834729_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 587.0
PYH2_k127_5834729_1 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000834 259.0
PYH2_k127_5837152_0 Heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 588.0
PYH2_k127_5837152_1 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 353.0
PYH2_k127_5837152_2 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000006756 224.0
PYH2_k127_5837152_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000003559 203.0
PYH2_k127_5837152_4 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000001195 156.0
PYH2_k127_5844516_0 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 353.0
PYH2_k127_5844516_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 326.0
PYH2_k127_5844516_2 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 289.0
PYH2_k127_5844516_3 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005219 282.0
PYH2_k127_5844516_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005293 248.0
PYH2_k127_5844516_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000001443 201.0
PYH2_k127_5844516_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000002688 196.0
PYH2_k127_5844516_7 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000000189 117.0
PYH2_k127_5844516_8 Protein of unknown function (DUF2845) - - - 0.0000000000000000004133 91.0
PYH2_k127_585309_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 436.0
PYH2_k127_585309_1 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 393.0
PYH2_k127_585309_2 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 390.0
PYH2_k127_585309_3 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
PYH2_k127_585309_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000003735 191.0
PYH2_k127_586042_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 1.006e-315 987.0
PYH2_k127_586042_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 459.0
PYH2_k127_586042_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 398.0
PYH2_k127_5868_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 606.0
PYH2_k127_5868_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000006471 181.0
PYH2_k127_5884795_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.435e-297 933.0
PYH2_k127_5884795_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 434.0
PYH2_k127_5884795_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 373.0
PYH2_k127_5884795_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
PYH2_k127_5884795_4 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001854 263.0
PYH2_k127_5884795_5 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000009362 227.0
PYH2_k127_5884795_6 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000105 156.0
PYH2_k127_5884795_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000002201 130.0
PYH2_k127_5884795_8 OsmC-like protein K07397 - - 0.0000000000000000001099 94.0
PYH2_k127_5893794_0 belongs to the CobB CobQ family K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 376.0
PYH2_k127_5893794_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000001194 155.0
PYH2_k127_5898997_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 289.0
PYH2_k127_5898997_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007083 242.0
PYH2_k127_5912733_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 559.0
PYH2_k127_5912733_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000023 115.0
PYH2_k127_5912733_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000001826 65.0
PYH2_k127_5912733_3 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000007438 57.0
PYH2_k127_5920796_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.386e-208 657.0
PYH2_k127_5920796_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 409.0
PYH2_k127_5920796_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000003108 149.0
PYH2_k127_5920796_11 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000003708 119.0
PYH2_k127_5920796_12 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.0000000000000000005479 93.0
PYH2_k127_5920796_13 Belongs to the UPF0235 family K09131 - - 0.0000000000000001894 81.0
PYH2_k127_5920796_2 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 395.0
PYH2_k127_5920796_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 310.0
PYH2_k127_5920796_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 283.0
PYH2_k127_5920796_5 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001498 254.0
PYH2_k127_5920796_6 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006532 246.0
PYH2_k127_5920796_7 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
PYH2_k127_5920796_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000001079 187.0
PYH2_k127_5920796_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000001777 183.0
PYH2_k127_5932780_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008656 270.0
PYH2_k127_5932780_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000001592 236.0
PYH2_k127_5932780_2 family 5 K15580 - - 0.00000000000000000000000000000001529 133.0
PYH2_k127_5932780_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000009668 119.0
PYH2_k127_5945233_0 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 545.0
PYH2_k127_5945233_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000742 214.0
PYH2_k127_5945233_2 rubredoxin - - - 0.000000000000000000000001309 103.0
PYH2_k127_5965395_0 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 366.0
PYH2_k127_5965395_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 332.0
PYH2_k127_5965395_2 Flagellar Motor Protein K02557 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009288,GO:0009425,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044425,GO:0044459,GO:0044461,GO:0044463,GO:0044464,GO:0071944,GO:0120100,GO:0120101 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007994 253.0
PYH2_k127_5965395_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000003695 225.0
PYH2_k127_5965395_4 diguanylate cyclase - - - 0.000000000000000000000000000003836 126.0
PYH2_k127_5965395_5 PFAM PilZ domain - - - 0.00004316 54.0
PYH2_k127_5986861_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 4.452e-304 972.0
PYH2_k127_5986861_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 442.0
PYH2_k127_5986861_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000005335 209.0
PYH2_k127_5986861_3 phosphorelay sensor kinase activity K07710,K10942 - 2.7.13.3 0.0000000000000000000000000000000000003991 151.0
PYH2_k127_6021314_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 372.0
PYH2_k127_6021314_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000005769 141.0
PYH2_k127_6021314_2 - - - - 0.00000000000000000000000000000000008487 134.0
PYH2_k127_6021314_3 Peptidase C26 K01658 - 4.1.3.27 0.000000000000001897 76.0
PYH2_k127_6021314_4 Domain of unknown function (DUF4258) - - - 0.0002801 46.0
PYH2_k127_6046068_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.181e-297 919.0
PYH2_k127_6046068_1 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 338.0
PYH2_k127_6046068_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 334.0
PYH2_k127_6046068_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000002484 204.0
PYH2_k127_6057814_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 490.0
PYH2_k127_6062977_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 296.0
PYH2_k127_6062977_1 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
PYH2_k127_6062977_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000007702 216.0
PYH2_k127_6062977_3 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000001398 171.0
PYH2_k127_6062977_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000002982 155.0
PYH2_k127_6062977_5 Cell envelope biogenesis protein TolA K03646 - - 0.000005616 57.0
PYH2_k127_6071920_0 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 4.986e-245 772.0
PYH2_k127_6071920_1 ABC transporter K06158 - - 4.056e-242 765.0
PYH2_k127_6071920_10 Epimerase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 336.0
PYH2_k127_6071920_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 276.0
PYH2_k127_6071920_12 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
PYH2_k127_6071920_13 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000003033 218.0
PYH2_k127_6071920_14 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000005584 201.0
PYH2_k127_6071920_15 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000003315 193.0
PYH2_k127_6071920_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000004625 192.0
PYH2_k127_6071920_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000001224 162.0
PYH2_k127_6071920_18 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000001737 147.0
PYH2_k127_6071920_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000009939 139.0
PYH2_k127_6071920_2 Endoribonuclease that initiates mRNA decay K18682 - - 4.313e-220 694.0
PYH2_k127_6071920_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000003252 105.0
PYH2_k127_6071920_21 - - - - 0.00000002586 57.0
PYH2_k127_6071920_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 616.0
PYH2_k127_6071920_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 547.0
PYH2_k127_6071920_5 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 484.0
PYH2_k127_6071920_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 431.0
PYH2_k127_6071920_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 433.0
PYH2_k127_6071920_8 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 385.0
PYH2_k127_6071920_9 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 365.0
PYH2_k127_6080569_0 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000006908 104.0
PYH2_k127_6080569_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000004169 56.0
PYH2_k127_608224_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1204.0
PYH2_k127_608224_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 327.0
PYH2_k127_608224_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000007151 177.0
PYH2_k127_608224_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000009196 153.0
PYH2_k127_6088178_0 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 424.0
PYH2_k127_6088178_1 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 409.0
PYH2_k127_6088178_10 PFAM secretion protein HlyD family protein K03543 - - 0.0000000008404 63.0
PYH2_k127_6088178_11 - - - - 0.0004584 47.0
PYH2_k127_6088178_2 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 397.0
PYH2_k127_6088178_5 YtkA-like - - - 0.0000000000000000000000000000000001651 144.0
PYH2_k127_6088178_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000001704 125.0
PYH2_k127_6088178_7 PIN domain K07065 - - 0.000000000000000000000000000009143 123.0
PYH2_k127_6088178_8 Transposase, Mutator family - - - 0.000000000000000000000006711 109.0
PYH2_k127_6088178_9 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000002204 113.0
PYH2_k127_6101977_0 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
PYH2_k127_6101977_1 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000000000000001235 170.0
PYH2_k127_6113704_0 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 515.0
PYH2_k127_6113704_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000008861 237.0
PYH2_k127_6119669_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 6.354e-196 618.0
PYH2_k127_6119669_1 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
PYH2_k127_6119669_2 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000001704 163.0
PYH2_k127_6119669_3 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000005592 128.0
PYH2_k127_6119669_4 electron transfer activity K05337,K17247 - - 0.00000000000000000000000005675 108.0
PYH2_k127_6124135_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 315.0
PYH2_k127_6124135_1 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 290.0
PYH2_k127_6124135_2 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000001176 208.0
PYH2_k127_6124135_3 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000104 190.0
PYH2_k127_6124135_4 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000001984 163.0
PYH2_k127_6139152_0 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 467.0
PYH2_k127_6193795_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 609.0
PYH2_k127_6193795_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 511.0
PYH2_k127_6193795_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003671 281.0
PYH2_k127_6193795_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
PYH2_k127_6193795_4 YGGT family K02221 - - 0.00000000000000000000000000000000002032 137.0
PYH2_k127_6193795_5 DivIVA protein K04074 - - 0.00000000000000000000000000000003221 128.0
PYH2_k127_6193795_6 - - - - 0.0000000000000000000000002627 111.0
PYH2_k127_6193795_7 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000001343 87.0
PYH2_k127_6198103_0 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 445.0
PYH2_k127_6198103_1 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000003518 196.0
PYH2_k127_6210873_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.641e-222 701.0
PYH2_k127_6210873_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 525.0
PYH2_k127_6210873_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000002632 178.0
PYH2_k127_6242882_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 617.0
PYH2_k127_6242882_1 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 534.0
PYH2_k127_6242882_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 429.0
PYH2_k127_6242882_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 354.0
PYH2_k127_6242882_4 Response regulator receiver domain - - - 0.000000003847 60.0
PYH2_k127_6251560_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.769e-234 743.0
PYH2_k127_6251560_1 flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 323.0
PYH2_k127_6251560_10 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000135 51.0
PYH2_k127_6251560_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005618 287.0
PYH2_k127_6251560_3 FliP family K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001706 256.0
PYH2_k127_6251560_4 Flagellar basal body rod protein K02390 - - 0.00000000000000000000000000000000000000002652 158.0
PYH2_k127_6251560_5 PFAM surface presentation of antigens (SPOA) protein K02417 - - 0.0000000000000000000000000000000000002818 143.0
PYH2_k127_6251560_6 Bacterial export proteins, family 1 K02421 - - 0.00000000000000000000000000000000001191 145.0
PYH2_k127_6251560_7 Role in flagellar biosynthesis K02420 - - 0.000000000000000000004757 95.0
PYH2_k127_6251560_8 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000004848 99.0
PYH2_k127_6251560_9 PFAM Flagellar biosynthesis protein, FliO K02418 - - 0.0000355 51.0
PYH2_k127_6264043_0 Belongs to the GPI family K01810 - 5.3.1.9 1.547e-297 919.0
PYH2_k127_6264043_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 561.0
PYH2_k127_6264043_2 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 301.0
PYH2_k127_6264043_3 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001203 252.0
PYH2_k127_6264043_4 Flagellar motor protein K02557 - - 0.0000000000000000000000000000000007647 139.0
PYH2_k127_6264043_5 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000006404 135.0
PYH2_k127_6264043_6 HDOD domain - - - 0.000000000000000000006158 98.0
PYH2_k127_631969_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 518.0
PYH2_k127_631969_1 Histidine kinase - - - 0.0000000000000000000000000002438 123.0
PYH2_k127_631969_2 response regulator, receiver - - - 0.000000000000000000000000005119 115.0
PYH2_k127_631969_3 Response regulator receiver domain - - - 0.00000228 51.0
PYH2_k127_631969_4 Arsenical pump membrane protein K03893 - - 0.000006093 48.0
PYH2_k127_6324475_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.514e-207 653.0
PYH2_k127_6324475_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 490.0
PYH2_k127_6324475_2 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000005145 160.0
PYH2_k127_634140_0 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000003625 201.0
PYH2_k127_634140_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000002273 166.0
PYH2_k127_634140_2 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000001919 148.0
PYH2_k127_634140_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000001886 119.0
PYH2_k127_6356108_0 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006831 248.0
PYH2_k127_6356108_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000001303 151.0
PYH2_k127_6356108_2 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000000004202 145.0
PYH2_k127_6356108_3 - - - - 0.000000000005588 72.0
PYH2_k127_6377518_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 486.0
PYH2_k127_6377518_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
PYH2_k127_6377518_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000015 252.0
PYH2_k127_6377518_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000001194 139.0
PYH2_k127_6377518_4 Belongs to the 'phage' integrase family - - - 0.000000000000007677 79.0
PYH2_k127_6391732_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.029e-213 671.0
PYH2_k127_6391732_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 496.0
PYH2_k127_6391732_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 383.0
PYH2_k127_6391732_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 348.0
PYH2_k127_6391732_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
PYH2_k127_6395026_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 568.0
PYH2_k127_6395026_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 457.0
PYH2_k127_6395026_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 376.0
PYH2_k127_6409416_0 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 336.0
PYH2_k127_6438285_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 370.0
PYH2_k127_6438285_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
PYH2_k127_6438285_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000817 47.0
PYH2_k127_6556696_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.555e-237 741.0
PYH2_k127_6556696_1 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 364.0
PYH2_k127_6556696_2 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000006912 229.0
PYH2_k127_6556696_3 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000009375 154.0
PYH2_k127_6556696_5 Transposase - - - 0.0000000000001241 75.0
PYH2_k127_6556696_6 transferase activity, transferring glycosyl groups - - - 0.00002521 57.0
PYH2_k127_6562853_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 2.879e-224 706.0
PYH2_k127_6562853_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 344.0
PYH2_k127_6562853_2 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000004243 160.0
PYH2_k127_6562853_3 Single-strand DNA-specific exonuclease, C terminal domain K07462 - - 0.0000000000000000000000000000116 122.0
PYH2_k127_6565726_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 406.0
PYH2_k127_6565726_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000875 223.0
PYH2_k127_6565726_2 protein complex oligomerization - - - 0.0000000000000000000000000000000009294 139.0
PYH2_k127_6565726_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000001381 99.0
PYH2_k127_6570239_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 373.0
PYH2_k127_6570239_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000009189 170.0
PYH2_k127_6570239_2 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000001256 78.0
PYH2_k127_6570239_3 - - - - 0.0000005062 57.0
PYH2_k127_6581692_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 373.0
PYH2_k127_6581692_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
PYH2_k127_6581692_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000003497 261.0
PYH2_k127_6581692_3 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000003228 174.0
PYH2_k127_6596987_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.459e-248 775.0
PYH2_k127_6596987_1 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 573.0
PYH2_k127_6596987_2 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000009282 233.0
PYH2_k127_6596987_3 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000001229 88.0
PYH2_k127_6596987_4 Type II secretion system protein B K02451 - - 0.000000000000000007985 93.0
PYH2_k127_6612075_0 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 327.0
PYH2_k127_6612075_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 291.0
PYH2_k127_6612075_2 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000008365 228.0
PYH2_k127_6618350_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 563.0
PYH2_k127_6618350_1 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 457.0
PYH2_k127_6618350_2 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000004661 174.0
PYH2_k127_6618350_3 RDD family - - - 0.000000000000000000000000000000006647 134.0
PYH2_k127_6618350_4 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000002149 125.0
PYH2_k127_6618350_5 - - - - 0.00000000000000272 81.0
PYH2_k127_6630331_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 444.0
PYH2_k127_6630331_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000002908 135.0
PYH2_k127_663405_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 568.0
PYH2_k127_663405_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000642 237.0
PYH2_k127_663405_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001453 228.0
PYH2_k127_663405_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
PYH2_k127_6634184_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 329.0
PYH2_k127_6634184_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 304.0
PYH2_k127_6634184_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001506 275.0
PYH2_k127_6634184_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000002162 212.0
PYH2_k127_6634184_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000001536 174.0
PYH2_k127_6634184_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000001599 149.0
PYH2_k127_6634184_6 Sulfurtransferase TusA - - - 0.00000000000000000000000308 104.0
PYH2_k127_664460_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 1.756e-205 654.0
PYH2_k127_664460_2 domain protein K20276 - - 0.0000005201 52.0
PYH2_k127_6652737_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000294 243.0
PYH2_k127_6652737_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000102 217.0
PYH2_k127_6652737_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000151 198.0
PYH2_k127_6652737_3 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000405 184.0
PYH2_k127_6653964_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 463.0
PYH2_k127_6653964_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001101 256.0
PYH2_k127_6653964_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000003249 256.0
PYH2_k127_6655948_0 Pfam:KaiC K08482 - - 2.599e-222 702.0
PYH2_k127_6655948_1 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000004997 177.0
PYH2_k127_6655948_2 KaiB K08481 - - 0.000000000000000000000000000000000000000000506 159.0
PYH2_k127_6655948_3 KaiB K08481 - - 0.0000000000000000000000000000000000006186 145.0
PYH2_k127_6655948_4 COG0642 Signal transduction histidine kinase - - - 0.000000000000000006038 85.0
PYH2_k127_6657013_0 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 428.0
PYH2_k127_6657013_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 407.0
PYH2_k127_6657013_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001556 275.0
PYH2_k127_6657013_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000001267 85.0
PYH2_k127_6685121_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 5.876e-209 660.0
PYH2_k127_6685121_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 339.0
PYH2_k127_6685121_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000001211 161.0
PYH2_k127_6689064_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.001e-258 809.0
PYH2_k127_6689064_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 394.0
PYH2_k127_6689064_2 membrane K00389 - - 0.00000000000000000000000000000000000000000004711 164.0
PYH2_k127_6689064_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000003689 118.0
PYH2_k127_6698592_0 Domain of unknown function (DUF4070) - - - 3.945e-213 674.0
PYH2_k127_6698592_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 7.2e-212 667.0
PYH2_k127_6698592_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 349.0
PYH2_k127_6698592_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 319.0
PYH2_k127_6698592_4 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000001273 169.0
PYH2_k127_6698592_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.0000000000000000000000000000433 125.0
PYH2_k127_6698592_6 Transcriptional regulator - - - 0.000000000000000000000000004372 119.0
PYH2_k127_6698592_7 Ribosomal RNA adenine dimethylase - - - 0.000000000002109 74.0
PYH2_k127_6698592_8 - - - - 0.0000002489 58.0
PYH2_k127_6704009_0 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 379.0
PYH2_k127_6704009_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 371.0
PYH2_k127_6704009_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000007673 84.0
PYH2_k127_6704009_3 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000001364 68.0
PYH2_k127_6710148_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 463.0
PYH2_k127_6710148_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 457.0
PYH2_k127_6710148_2 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 311.0
PYH2_k127_6710148_3 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000000000000000000000000000004817 144.0
PYH2_k127_6714643_0 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 576.0
PYH2_k127_6714643_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 591.0
PYH2_k127_6714643_10 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002723 232.0
PYH2_k127_6714643_11 Lipocalin-like domain - - - 0.000000000000000000000000000002253 127.0
PYH2_k127_6714643_12 SMART Cold shock protein K03704 - - 0.000000000000000000000000008395 112.0
PYH2_k127_6714643_13 - - - - 0.0000000000000000000000003069 110.0
PYH2_k127_6714643_15 FtsX-like permease family K02004 - - 0.0000000006125 60.0
PYH2_k127_6714643_16 Protein of unknown function (DUF2934) - - - 0.0002586 47.0
PYH2_k127_6714643_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
PYH2_k127_6714643_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 477.0
PYH2_k127_6714643_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 413.0
PYH2_k127_6714643_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 415.0
PYH2_k127_6714643_6 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 355.0
PYH2_k127_6714643_7 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 324.0
PYH2_k127_6714643_8 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005104 285.0
PYH2_k127_6714643_9 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
PYH2_k127_6716461_0 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000009226 233.0
PYH2_k127_6716461_1 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000000004098 175.0
PYH2_k127_6722152_0 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 287.0
PYH2_k127_6722152_1 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004933 250.0
PYH2_k127_6722152_2 Nitroreductase - - - 0.00000000000000000000000000000000000000003398 152.0
PYH2_k127_6722484_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 315.0
PYH2_k127_6722484_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000002579 205.0
PYH2_k127_6722484_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000003167 89.0
PYH2_k127_6736239_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 460.0
PYH2_k127_6736239_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 319.0
PYH2_k127_6736239_2 repeat-containing protein - - - 0.00000000000000000000000000000008915 130.0
PYH2_k127_6736239_3 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.0000000002988 66.0
PYH2_k127_6736239_4 Histidine kinase - - - 0.000131 49.0
PYH2_k127_6740326_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 400.0
PYH2_k127_6740326_1 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000009276 233.0
PYH2_k127_6740326_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000001071 61.0
PYH2_k127_6744918_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.635e-228 714.0
PYH2_k127_6744918_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 588.0
PYH2_k127_6751164_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2072.0
PYH2_k127_6751164_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.018e-296 919.0
PYH2_k127_6751164_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 359.0
PYH2_k127_6751164_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009608 280.0
PYH2_k127_6751164_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003179 239.0
PYH2_k127_6751164_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000001857 190.0
PYH2_k127_6751164_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000001625 150.0
PYH2_k127_6751164_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000005712 86.0
PYH2_k127_6751164_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000003766 78.0
PYH2_k127_6751164_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000002985 72.0
PYH2_k127_6756145_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 394.0
PYH2_k127_6756145_1 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003497 251.0
PYH2_k127_6756145_2 Helix-turn-helix domain of transposase family ISL3 - - - 0.0000000000000005129 80.0
PYH2_k127_6756145_3 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0007702 51.0
PYH2_k127_6757012_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 464.0
PYH2_k127_6757012_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
PYH2_k127_6757012_2 - - - - 0.00000003811 61.0
PYH2_k127_6774069_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 445.0
PYH2_k127_6774069_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 327.0
PYH2_k127_6774069_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 293.0
PYH2_k127_6774069_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001083 258.0
PYH2_k127_6774069_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
PYH2_k127_6774069_5 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000001544 142.0
PYH2_k127_6774069_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000004869 49.0
PYH2_k127_6793042_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 493.0
PYH2_k127_6793042_1 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 452.0
PYH2_k127_6793042_2 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 261.0
PYH2_k127_6793042_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002438 249.0
PYH2_k127_6793042_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000003554 149.0
PYH2_k127_6793042_5 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000002453 83.0
PYH2_k127_6793042_6 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000002995 73.0
PYH2_k127_6793042_7 PFAM Tetratricopeptide repeat - - - 0.00002675 57.0
PYH2_k127_6827343_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 437.0
PYH2_k127_6827343_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 381.0
PYH2_k127_6827343_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 360.0
PYH2_k127_6827343_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 319.0
PYH2_k127_6827343_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 295.0
PYH2_k127_6827343_5 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000005475 183.0
PYH2_k127_6827343_6 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000008712 161.0
PYH2_k127_6827343_7 PFAM Nitroreductase - - - 0.000000000000000000000000000000004507 134.0
PYH2_k127_6827343_8 response regulator - - - 0.0004584 47.0
PYH2_k127_68382_0 PFAM flagellin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 290.0
PYH2_k127_68382_1 diguanylate cyclase - - - 0.0000000000000000000000000000000499 129.0
PYH2_k127_6847809_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 373.0
PYH2_k127_6847809_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 340.0
PYH2_k127_6847809_2 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 326.0
PYH2_k127_6847809_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000005801 201.0
PYH2_k127_6847809_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000003113 146.0
PYH2_k127_6847809_6 Transcriptional - - - 0.000000000000000000000000000000000001672 139.0
PYH2_k127_6847809_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000004125 120.0
PYH2_k127_688809_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 445.0
PYH2_k127_688809_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 410.0
PYH2_k127_688809_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
PYH2_k127_688809_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000002043 253.0
PYH2_k127_688809_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000001188 219.0
PYH2_k127_688809_5 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000009045 141.0
PYH2_k127_6906159_0 - - - - 3.098e-200 630.0
PYH2_k127_6906159_1 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 600.0
PYH2_k127_6906159_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 283.0
PYH2_k127_6906159_3 - K09004 - - 0.0000000000000000000000000000000000000000000000007111 177.0
PYH2_k127_6966799_0 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 587.0
PYH2_k127_6966799_1 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000000001008 185.0
PYH2_k127_6966799_2 translation release factor activity - - - 0.00001336 48.0
PYH2_k127_6966799_3 Beta-lactamase - - - 0.00004399 53.0
PYH2_k127_6990829_0 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 586.0
PYH2_k127_6990829_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000004207 246.0
PYH2_k127_6990829_2 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000008327 146.0
PYH2_k127_6990829_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000003207 81.0
PYH2_k127_6993506_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 363.0
PYH2_k127_6993506_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 332.0
PYH2_k127_6993506_2 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000298 209.0
PYH2_k127_7014105_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 404.0
PYH2_k127_702032_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.371e-221 701.0
PYH2_k127_702032_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.251e-211 669.0
PYH2_k127_702032_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 329.0
PYH2_k127_7081332_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 343.0
PYH2_k127_7081332_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 329.0
PYH2_k127_7081332_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002585 267.0
PYH2_k127_7093164_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 566.0
PYH2_k127_7093164_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 457.0
PYH2_k127_7093164_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 406.0
PYH2_k127_7093164_3 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 347.0
PYH2_k127_7093164_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001869 260.0
PYH2_k127_7093164_5 ABC transporter (Permease K02026 - - 0.000000000000000000002379 98.0
PYH2_k127_7106452_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
PYH2_k127_7106452_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000003707 156.0
PYH2_k127_7106452_2 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000009124 134.0
PYH2_k127_7106452_3 - - - - 0.00000000000000000000000000002816 117.0
PYH2_k127_7106452_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.000003899 48.0
PYH2_k127_7139009_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 2.114e-223 703.0
PYH2_k127_7139009_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000001294 216.0
PYH2_k127_7156723_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 431.0
PYH2_k127_7156723_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 388.0
PYH2_k127_7156723_2 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000000000000000000000000000000000000000000001783 199.0
PYH2_k127_7156723_3 - - - - 0.00000000000000000000000000000000008996 135.0
PYH2_k127_7156723_4 PFAM UbiE COQ5 methyltransferase - - - 0.0000000000000000000000000000001697 131.0
PYH2_k127_7156723_5 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000001197 124.0
PYH2_k127_7156723_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0005693 43.0
PYH2_k127_7202860_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.342e-201 632.0
PYH2_k127_7202860_1 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 596.0
PYH2_k127_7202860_2 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 571.0
PYH2_k127_7202860_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 499.0
PYH2_k127_7202860_4 SEC-C Motif Domain Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006918 268.0
PYH2_k127_7202860_5 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004829 243.0
PYH2_k127_7202860_6 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000001007 205.0
PYH2_k127_7202860_7 deoxyhypusine monooxygenase activity K05385 - - 0.000000000000000000000000000000000000000000000002566 186.0
PYH2_k127_7257944_0 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 458.0
PYH2_k127_7257944_1 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000002855 243.0
PYH2_k127_7257944_2 PFAM toluene tolerance K07323 - - 0.0000000000000000000000000000000000000001517 159.0
PYH2_k127_7258396_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004869 255.0
PYH2_k127_7258396_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000001251 229.0
PYH2_k127_7258396_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000091 224.0
PYH2_k127_7258396_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000007817 197.0
PYH2_k127_7258396_4 SurA N-terminal domain K03771 - 5.2.1.8 0.00006939 52.0
PYH2_k127_7268352_0 4Fe-4S dicluster domain - - - 4.771e-302 932.0
PYH2_k127_7268352_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.169e-240 750.0
PYH2_k127_7268352_10 - - - - 0.0000000000000000000000000000000000002401 145.0
PYH2_k127_7268352_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000195 86.0
PYH2_k127_7268352_12 lyase activity - - - 0.00000000008382 65.0
PYH2_k127_7268352_13 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000003963 63.0
PYH2_k127_7268352_14 DsrE/DsrF-like family K07235 - - 0.00000009913 58.0
PYH2_k127_7268352_15 Belongs to the DsrF TusC family K07236 - - 0.00007601 50.0
PYH2_k127_7268352_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 546.0
PYH2_k127_7268352_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 490.0
PYH2_k127_7268352_4 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 449.0
PYH2_k127_7268352_5 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
PYH2_k127_7268352_6 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009068 283.0
PYH2_k127_7268352_7 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000001103 207.0
PYH2_k127_7268352_8 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000000000001843 177.0
PYH2_k127_7268352_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000001475 154.0
PYH2_k127_7290473_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 396.0
PYH2_k127_7290473_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002493 246.0
PYH2_k127_7290473_2 transferase activity, transferring glycosyl groups - - - 0.00000000000001833 75.0
PYH2_k127_7306218_0 Elongation factor G, domain IV K02355 - - 7.296e-226 710.0
PYH2_k127_7306218_1 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000000000003502 101.0
PYH2_k127_7306218_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000001528 55.0
PYH2_k127_7317308_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 529.0
PYH2_k127_7396433_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 440.0
PYH2_k127_7396433_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 304.0
PYH2_k127_7396433_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000287 205.0
PYH2_k127_7396433_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000001604 184.0
PYH2_k127_7396433_4 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.0000000000000000000000000000000000000000000000001163 181.0
PYH2_k127_7396433_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000001316 118.0
PYH2_k127_7422650_0 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 375.0
PYH2_k127_7422650_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000006194 101.0
PYH2_k127_7422650_2 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.0000000000000000000003952 98.0
PYH2_k127_7436672_0 Cellulose biosynthesis protein BcsQ K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 280.0
PYH2_k127_7436672_1 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000002787 173.0
PYH2_k127_744859_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.082e-221 694.0
PYH2_k127_744859_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.787e-199 632.0
PYH2_k127_744859_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001949 72.0
PYH2_k127_744859_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 370.0
PYH2_k127_744859_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 321.0
PYH2_k127_744859_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 299.0
PYH2_k127_744859_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000001405 205.0
PYH2_k127_744859_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005148 200.0
PYH2_k127_744859_7 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001689 180.0
PYH2_k127_744859_8 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001009 157.0
PYH2_k127_744859_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000004751 131.0
PYH2_k127_7479197_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1153.0
PYH2_k127_7479197_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000811 244.0
PYH2_k127_7479197_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001617 219.0
PYH2_k127_7485131_0 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002584 277.0
PYH2_k127_7485131_1 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001893 269.0
PYH2_k127_7485131_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000006019 245.0
PYH2_k127_7485131_3 DoxX K15977 - - 0.00000000000000000000000000000000000000000009652 163.0
PYH2_k127_7485131_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000002675 149.0
PYH2_k127_7485131_5 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000462 79.0
PYH2_k127_7487599_0 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 569.0
PYH2_k127_7487599_1 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 396.0
PYH2_k127_7487599_2 Smr domain - - - 0.0000000000000000000000000000000311 134.0
PYH2_k127_7487599_3 Trypsin-like peptidase domain - - - 0.00000000000000000000000000002771 131.0
PYH2_k127_7487599_4 peptidyl-tyrosine sulfation - - - 0.000000000000417 81.0
PYH2_k127_7491238_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 6.113e-235 734.0
PYH2_k127_7491238_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000008167 193.0
PYH2_k127_7491238_2 - - - - 0.0000000000000000000000000000000000000000000000004562 178.0
PYH2_k127_7491238_3 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000004666 84.0
PYH2_k127_7494845_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 536.0
PYH2_k127_7494845_1 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 407.0
PYH2_k127_7494845_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 355.0
PYH2_k127_7494845_3 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000005492 184.0
PYH2_k127_7494845_4 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000009209 179.0
PYH2_k127_7494845_5 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000002098 157.0
PYH2_k127_7494845_6 Regulatory protein, FmdB family - - - 0.00000000000000000000001202 102.0
PYH2_k127_7494845_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000003607 95.0
PYH2_k127_7494845_9 Amidohydrolase - - - 0.00002315 47.0
PYH2_k127_750772_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 413.0
PYH2_k127_750772_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 370.0
PYH2_k127_7512390_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 6.318e-204 657.0
PYH2_k127_7512390_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 581.0
PYH2_k127_7512390_2 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000001124 271.0
PYH2_k127_7512837_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 563.0
PYH2_k127_7512837_1 Tyrosine recombinase XerD K04763 - - 0.00002798 48.0
PYH2_k127_7531389_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 533.0
PYH2_k127_7531389_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 411.0
PYH2_k127_7531389_2 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000001021 171.0
PYH2_k127_7531389_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000001425 165.0
PYH2_k127_7532678_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008656 263.0
PYH2_k127_7532678_1 MarR family transcriptional K15973 - - 0.0000000000000000000000000000000000000000000008447 169.0
PYH2_k127_7532678_2 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.000000000222 62.0
PYH2_k127_7541097_0 DNA photolyase K01669 - 4.1.99.3 4.093e-198 627.0
PYH2_k127_7541097_1 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 394.0
PYH2_k127_7541097_10 DsrE/DsrF-like family K07236 - - 0.00005104 51.0
PYH2_k127_7541097_2 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 309.0
PYH2_k127_7541097_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 300.0
PYH2_k127_7541097_4 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001963 271.0
PYH2_k127_7541097_5 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005646 268.0
PYH2_k127_7541097_6 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000001584 260.0
PYH2_k127_7541097_7 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000001104 244.0
PYH2_k127_7541097_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009398 230.0
PYH2_k127_7541097_9 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000001173 209.0
PYH2_k127_7541573_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 582.0
PYH2_k127_7541573_1 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 293.0
PYH2_k127_7541573_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.00000000000000000000002089 102.0
PYH2_k127_7541573_11 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000006319 106.0
PYH2_k127_7541573_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001398 274.0
PYH2_k127_7541573_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000002087 224.0
PYH2_k127_7541573_4 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000151 217.0
PYH2_k127_7541573_5 3-oxoacyl- acyl-carrier-protein reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000005063 169.0
PYH2_k127_7541573_6 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000000002261 158.0
PYH2_k127_7541573_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000002476 146.0
PYH2_k127_7541573_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000006604 121.0
PYH2_k127_7548933_0 GTP-binding protein TypA K06207 - - 2.85e-264 825.0
PYH2_k127_7548933_1 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000468 158.0
PYH2_k127_7548933_2 peptidase K02236,K02654 - 3.4.23.43 0.000000007043 57.0
PYH2_k127_7555580_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 575.0
PYH2_k127_7555580_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 338.0
PYH2_k127_7564130_0 AsmA-like C-terminal region - - - 3.355e-216 714.0
PYH2_k127_7564130_1 PFAM thioesterase superfamily K02614 - - 0.0000000000004469 69.0
PYH2_k127_7568967_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 536.0
PYH2_k127_7568967_1 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000000000002351 157.0
PYH2_k127_7568967_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000003609 117.0
PYH2_k127_7568967_4 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.000005206 49.0
PYH2_k127_7578139_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 392.0
PYH2_k127_7578139_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000009163 243.0
PYH2_k127_7578139_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000004686 123.0
PYH2_k127_7578139_3 Domain of unknown function (DUF2703) - - - 0.00000000000001378 80.0
PYH2_k127_7578495_0 Sigma-54 interaction domain - - - 1.177e-209 660.0
PYH2_k127_7578495_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 575.0
PYH2_k127_7578495_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 428.0
PYH2_k127_7578495_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000588 282.0
PYH2_k127_7578495_4 phosphorelay sensor kinase activity K07708,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000003253 183.0
PYH2_k127_7578495_5 Universal stress protein family - - - 0.0001565 52.0
PYH2_k127_7582057_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 580.0
PYH2_k127_7582057_1 PFAM ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001825 228.0
PYH2_k127_7584502_0 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 561.0
PYH2_k127_7584502_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 323.0
PYH2_k127_7584502_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000008457 187.0
PYH2_k127_7586305_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 442.0
PYH2_k127_7586305_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 349.0
PYH2_k127_7586305_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000008171 220.0
PYH2_k127_7586305_3 protein-disulfide reductase activity - - - 0.0000000000000000000000000001383 121.0
PYH2_k127_7586305_4 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000001174 74.0
PYH2_k127_7586305_5 transferase activity, transferring glycosyl groups - - - 0.00000001416 62.0
PYH2_k127_7586305_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001796 64.0
PYH2_k127_759122_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 397.0
PYH2_k127_759122_1 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 383.0
PYH2_k127_759122_2 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008903 234.0
PYH2_k127_7603317_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 590.0
PYH2_k127_7603317_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 342.0
PYH2_k127_7603317_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000001005 143.0
PYH2_k127_7603317_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000004548 84.0
PYH2_k127_7603317_4 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000000000009679 86.0
PYH2_k127_7603317_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00008883 52.0
PYH2_k127_7603858_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 285.0
PYH2_k127_7603858_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000001419 158.0
PYH2_k127_7603858_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000006648 127.0
PYH2_k127_7603858_3 Belongs to the bacterial flagellin family K02397 - - 0.00000000000000000000000000002185 130.0
PYH2_k127_7603858_4 Glycosyl hydrolase 108 K08309 - - 0.00000000000000000003483 103.0
PYH2_k127_7603858_6 PFAM Anti-sigma-28 factor FlgM K02398 - - 0.00004286 49.0
PYH2_k127_7603858_7 Predicted Peptidoglycan domain - - - 0.00009233 54.0
PYH2_k127_7627645_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 481.0
PYH2_k127_7627645_1 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 449.0
PYH2_k127_7627645_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 381.0
PYH2_k127_7627645_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 GO:0003674,GO:0003824,GO:0004090,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0008152,GO:0009056,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0031132,GO:0031224,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044464,GO:0055114,GO:0071704,GO:1901575 1.1.1.381 0.000000000000000000000000001809 120.0
PYH2_k127_764274_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000004375 238.0
PYH2_k127_764274_1 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000004573 139.0
PYH2_k127_764274_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000001499 129.0
PYH2_k127_7643450_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 568.0
PYH2_k127_7643450_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007159 253.0
PYH2_k127_7643450_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000122 247.0
PYH2_k127_7643450_3 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000000001143 197.0
PYH2_k127_7643450_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000002358 169.0
PYH2_k127_7643450_5 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000002176 148.0
PYH2_k127_7643450_6 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000004873 149.0
PYH2_k127_7643450_8 (SAM)-dependent - - - 0.00000001484 57.0
PYH2_k127_7643450_9 Protein of unknown function (DUF3592) - - - 0.0000009226 53.0
PYH2_k127_7676642_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 422.0
PYH2_k127_7676642_1 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007197 249.0
PYH2_k127_7676642_2 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.000000000000000000000000000000000000000000000000000000002963 204.0
PYH2_k127_7676642_3 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000000002566 192.0
PYH2_k127_7676642_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000009402 183.0
PYH2_k127_7676642_5 SMART Cold shock protein K03704 - - 0.000000000000000000000000005198 111.0
PYH2_k127_7678736_0 FAD linked oxidase K18930 - - 0.0 1193.0
PYH2_k127_7678736_1 l-lactate permease K02550,K03303 - - 1.826e-258 807.0
PYH2_k127_7678736_2 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000301 192.0
PYH2_k127_7678736_3 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.00000000000000000000000000000000000000004416 156.0
PYH2_k127_7703745_0 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 454.0
PYH2_k127_7703745_1 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000133 102.0
PYH2_k127_7703745_2 Major facilitator superfamily - - - 0.0000000000000528 80.0
PYH2_k127_7703745_3 Evidence 5 No homology to any previously reported sequences K07245,K14166 - - 0.00000004624 58.0
PYH2_k127_7726429_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.622e-216 681.0
PYH2_k127_7726429_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008755 256.0
PYH2_k127_7726429_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000125 60.0
PYH2_k127_77719_0 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 1.972e-195 614.0
PYH2_k127_77719_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 474.0
PYH2_k127_77719_2 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 425.0
PYH2_k127_77719_3 cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 355.0
PYH2_k127_7798360_0 synthase - - - 0.0 2541.0
PYH2_k127_7798360_1 Telomere recombination K04656 - - 6.732e-276 870.0
PYH2_k127_7798360_10 Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) - - - 0.000000000000000000000000000000000000000000006148 169.0
PYH2_k127_7798360_11 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000000000004271 163.0
PYH2_k127_7798360_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001009 160.0
PYH2_k127_7798360_13 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000000000009442 136.0
PYH2_k127_7798360_14 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000001236 149.0
PYH2_k127_7798360_15 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000003599 143.0
PYH2_k127_7798360_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000004938 132.0
PYH2_k127_7798360_17 cell redox homeostasis K02199 - - 0.00000000000000000000000000003904 123.0
PYH2_k127_7798360_18 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000006783 117.0
PYH2_k127_7798360_19 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.0000000000000000000001399 106.0
PYH2_k127_7798360_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 9.913e-205 644.0
PYH2_k127_7798360_20 outer membrane efflux protein K12340 - - 0.00000000002093 76.0
PYH2_k127_7798360_3 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 451.0
PYH2_k127_7798360_4 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 291.0
PYH2_k127_7798360_5 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 295.0
PYH2_k127_7798360_6 ABC transporter K02003,K09814 - - 0.0000000000000000000000000000000000000000000000000000000000000003223 227.0
PYH2_k127_7798360_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001034 216.0
PYH2_k127_7798360_8 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000003148 197.0
PYH2_k127_7798360_9 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000000000000002905 181.0
PYH2_k127_7799930_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 7.163e-288 897.0
PYH2_k127_7799930_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 580.0
PYH2_k127_7799930_2 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 558.0
PYH2_k127_7799930_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 359.0
PYH2_k127_7799930_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000001168 122.0
PYH2_k127_7799930_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000009641 111.0
PYH2_k127_7799930_6 - - - - 0.0000000000000000000002996 99.0
PYH2_k127_7799930_7 CBS domain containing protein K00974 - 2.7.7.72 0.0000000004252 62.0
PYH2_k127_7809894_0 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
PYH2_k127_7809894_1 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009386 266.0
PYH2_k127_7809894_2 COG0058 Glucan phosphorylase - - - 0.000000000000000000003702 93.0
PYH2_k127_7809894_3 - - - - 0.000000000000001939 79.0
PYH2_k127_7877935_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 297.0
PYH2_k127_7877935_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008764 268.0
PYH2_k127_7877935_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000238 162.0
PYH2_k127_7886310_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 541.0
PYH2_k127_7886310_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 519.0
PYH2_k127_7886310_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 385.0
PYH2_k127_7886310_3 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000009062 86.0
PYH2_k127_7899543_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 496.0
PYH2_k127_7899543_1 VanZ like family - - - 0.0000000000000000000000000000000000000000001244 164.0
PYH2_k127_7902311_0 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 372.0
PYH2_k127_7902311_1 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000001591 110.0
PYH2_k127_7915522_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 395.0
PYH2_k127_7915522_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 308.0
PYH2_k127_7915522_2 Cell cycle protein K03588 - - 0.0000000000000001829 83.0
PYH2_k127_7928860_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000001112 110.0
PYH2_k127_7928860_1 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000003594 97.0
PYH2_k127_7928860_2 PFAM Integrase catalytic region K07497 - - 0.00000000004536 63.0
PYH2_k127_7928860_3 - - - - 0.0000000001359 66.0
PYH2_k127_7945347_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 2.087e-203 641.0
PYH2_k127_7945347_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002788 284.0
PYH2_k127_7945347_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000004098 209.0
PYH2_k127_7945347_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.00000000000000000000000000000000000000000000008858 181.0
PYH2_k127_7945347_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001054 163.0
PYH2_k127_7945347_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000006388 145.0
PYH2_k127_7945347_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000007516 96.0
PYH2_k127_7945347_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000462 79.0
PYH2_k127_7953539_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 541.0
PYH2_k127_7953539_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000000008112 152.0
PYH2_k127_7953539_2 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000000000000003353 139.0
PYH2_k127_7953539_3 Modulates RecA activity - - - 0.0004237 48.0
PYH2_k127_7960706_0 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000009794 196.0
PYH2_k127_7960706_1 CARDB domain-containing protein,subtilase family protease - - - 0.0000000000000000000000001516 111.0
PYH2_k127_7960706_2 ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein - - - 0.00000000000000009095 84.0
PYH2_k127_8038559_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 578.0
PYH2_k127_8038559_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000001324 206.0
PYH2_k127_8038559_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000009496 134.0
PYH2_k127_8094056_0 Elongation factor SelB, winged helix K03833 - - 8.196e-232 734.0
PYH2_k127_8094056_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 553.0
PYH2_k127_8094056_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 321.0
PYH2_k127_8094056_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008934 271.0
PYH2_k127_8094056_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000536 199.0
PYH2_k127_8094056_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000001663 184.0
PYH2_k127_8094056_6 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000001178 86.0
PYH2_k127_8094056_7 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.00000000000004664 79.0
PYH2_k127_8105196_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 444.0
PYH2_k127_8105196_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 303.0
PYH2_k127_8105196_2 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000003019 70.0
PYH2_k127_8135410_0 Protein conserved in bacteria - - - 2.394e-196 642.0
PYH2_k127_8135410_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 274.0
PYH2_k127_8135410_2 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
PYH2_k127_8135410_3 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000000000000008539 191.0
PYH2_k127_8135410_4 - - - - 0.0000000000000000000000000000005203 123.0
PYH2_k127_8135410_5 Histidine kinase K02486,K10726 - 2.7.13.3 0.0001577 50.0
PYH2_k127_8141929_0 CbbQ/NirQ/NorQ C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 372.0
PYH2_k127_8141929_1 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 295.0
PYH2_k127_8141929_2 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000000000000006489 171.0
PYH2_k127_8141929_3 - - - - 0.00000000000000000000001566 105.0
PYH2_k127_8147262_0 sulfate assimilation K00958 - 2.7.7.4 2.69e-199 627.0
PYH2_k127_8147262_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 360.0
PYH2_k127_8147262_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000192 221.0
PYH2_k127_8147262_3 - - - - 0.00000001899 57.0
PYH2_k127_8170390_0 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 529.0
PYH2_k127_8170390_1 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 511.0
PYH2_k127_8170390_2 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 334.0
PYH2_k127_8170390_3 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.0000000000000000000003366 107.0
PYH2_k127_8224302_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.855e-223 703.0
PYH2_k127_8224302_1 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000114 127.0
PYH2_k127_8224302_2 - - - - 0.0000000000000000000000000007329 115.0
PYH2_k127_8224302_3 - - - - 0.00000002314 57.0
PYH2_k127_824399_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.396e-242 758.0
PYH2_k127_824399_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000007345 202.0
PYH2_k127_8245692_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 2.224e-205 657.0
PYH2_k127_8245692_1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001306 278.0
PYH2_k127_8245692_2 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000000004011 170.0
PYH2_k127_8287243_0 Domain of unknown function (DUF932) - - - 0.0000000000000000000000000000000000000000001014 171.0
PYH2_k127_8287243_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000003766 126.0
PYH2_k127_8287243_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000396 126.0
PYH2_k127_8287243_3 PIN domain - - - 0.00000000000000000000000003505 115.0
PYH2_k127_8287243_4 PFAM SpoVT AbrB - - - 0.000000000000000017 84.0
PYH2_k127_8303965_0 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 373.0
PYH2_k127_8303965_1 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 335.0
PYH2_k127_8303965_2 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000009296 238.0
PYH2_k127_8303965_3 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 237.0
PYH2_k127_8303965_4 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000006358 220.0
PYH2_k127_8303965_5 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000005207 211.0
PYH2_k127_8303965_6 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000001241 186.0
PYH2_k127_8303965_7 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000002231 122.0
PYH2_k127_8303965_8 PFAM response regulator receiver K07658 - - 0.000000000000002827 79.0
PYH2_k127_8348122_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 536.0
PYH2_k127_8348122_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007926 262.0
PYH2_k127_8348122_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000001845 226.0
PYH2_k127_8348122_3 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000001777 163.0
PYH2_k127_8348122_4 glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000007302 116.0
PYH2_k127_8348122_5 Sulfotransferase family - - - 0.0000000000000775 76.0
PYH2_k127_8371908_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
PYH2_k127_8371908_1 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000005324 206.0
PYH2_k127_8371908_2 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000000000000002917 173.0
PYH2_k127_8371908_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000001721 164.0
PYH2_k127_8371908_4 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000001759 160.0
PYH2_k127_8371908_5 Cytochrome c - - - 0.0000000000000000000000000000000078 133.0
PYH2_k127_8371908_6 SEC-C motif - - - 0.0001904 53.0
PYH2_k127_8442513_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 554.0
PYH2_k127_8442513_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 507.0
PYH2_k127_8442513_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 346.0
PYH2_k127_8442513_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000005677 262.0
PYH2_k127_8442513_4 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009869 240.0
PYH2_k127_8442513_5 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000000001133 204.0
PYH2_k127_8442513_6 - - - - 0.000000000000000000309 91.0
PYH2_k127_8449656_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 496.0
PYH2_k127_8449656_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 303.0
PYH2_k127_8449656_2 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000007899 189.0
PYH2_k127_8472774_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.705e-201 631.0
PYH2_k127_8472774_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 417.0
PYH2_k127_8472774_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000004111 186.0
PYH2_k127_8472774_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000001631 65.0
PYH2_k127_8489456_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 463.0
PYH2_k127_8489456_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000001151 83.0
PYH2_k127_8509616_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1253.0
PYH2_k127_8516655_0 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004492 261.0
PYH2_k127_8516655_2 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000002031 131.0
PYH2_k127_8516655_3 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000007535 129.0
PYH2_k127_8517651_0 FecR protein - - - 0.0 1118.0
PYH2_k127_8517651_1 CHASE2 K01768 - 4.6.1.1 3.34e-259 819.0
PYH2_k127_8517651_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 443.0
PYH2_k127_8577157_0 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 493.0
PYH2_k127_8577157_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000004101 234.0
PYH2_k127_8577796_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 394.0
PYH2_k127_8577796_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000001551 66.0
PYH2_k127_8582762_0 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000009435 78.0
PYH2_k127_8582762_1 Type IV pilus assembly protein PilM; K02461 - - 0.00008429 54.0
PYH2_k127_8582762_2 Type II secretion system (T2SS), protein J K02459 - - 0.000108 48.0
PYH2_k127_8586073_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 465.0
PYH2_k127_8586073_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 325.0
PYH2_k127_8586073_10 Protein of unknown function (DUF2905) - - - 0.0000000000000000000001426 98.0
PYH2_k127_8586073_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 286.0
PYH2_k127_8586073_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
PYH2_k127_8586073_4 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000000000000000000002802 214.0
PYH2_k127_8586073_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000004394 206.0
PYH2_k127_8586073_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000001001 164.0
PYH2_k127_8586073_7 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000001964 133.0
PYH2_k127_8586073_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000008806 121.0
PYH2_k127_8586073_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000003401 113.0
PYH2_k127_8586934_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 373.0
PYH2_k127_8586934_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 301.0
PYH2_k127_8586934_2 Transcriptional modulator of MazE toxin, MazF K07171 - - 0.000000000000000004221 86.0
PYH2_k127_8600764_0 glucose sorbosone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 469.0
PYH2_k127_8600764_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 414.0
PYH2_k127_8600764_2 PFAM CBS domain - - - 0.00000000000000000000000000000000000007642 145.0
PYH2_k127_8600764_3 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000003229 134.0
PYH2_k127_8654352_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 434.0
PYH2_k127_8654352_1 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000417 245.0
PYH2_k127_8668346_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.331e-199 636.0
PYH2_k127_8668346_1 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 398.0
PYH2_k127_8668346_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 321.0
PYH2_k127_8695595_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 418.0
PYH2_k127_8695595_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 354.0
PYH2_k127_8695595_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000005673 226.0
PYH2_k127_8695595_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000044 194.0
PYH2_k127_8695595_4 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000175 192.0
PYH2_k127_8695595_5 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000513 166.0
PYH2_k127_8698633_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 546.0
PYH2_k127_8698633_1 belongs to the CobB CobQ family K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 386.0
PYH2_k127_8698633_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 280.0
PYH2_k127_8698633_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000003178 193.0
PYH2_k127_8698633_4 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.00000000000000000000000000000000000000000000000006125 183.0
PYH2_k127_870062_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 507.0
PYH2_k127_870062_1 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 384.0
PYH2_k127_870062_2 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 267.0
PYH2_k127_870062_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000003397 129.0
PYH2_k127_870062_4 Tetratricopeptide repeat-like domain - - - 0.00000000000000000003233 99.0
PYH2_k127_870062_5 sulfur relay protein TusB DsrH K07237 - - 0.00008505 48.0
PYH2_k127_870062_6 type IV pilus assembly PilZ - - - 0.000123 48.0
PYH2_k127_8713168_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 559.0
PYH2_k127_8729221_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 287.0
PYH2_k127_8729221_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000003436 209.0
PYH2_k127_8729221_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000004858 193.0
PYH2_k127_8729221_3 Cytochrome P460 - - - 0.0000000000000000000000000000000000002273 147.0
PYH2_k127_8729221_4 Domain of unknown function (DUF4262) - - - 0.0000000000005931 76.0
PYH2_k127_8743168_0 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000006073 190.0
PYH2_k127_8743168_1 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000001102 171.0
PYH2_k127_8743168_2 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000004723 159.0
PYH2_k127_8743168_3 - - - - 0.0000000000000000000000000000000000001112 151.0
PYH2_k127_8743168_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000001148 141.0
PYH2_k127_8746598_0 COGs COG1639 signal transduction protein - - - 0.00000000000000000000000000000000000000000000002401 186.0
PYH2_k127_8746598_1 Universal stress protein family - - - 0.0000000000000000000000000000000000000001678 154.0
PYH2_k127_8746598_2 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000000000000000003644 158.0
PYH2_k127_8746598_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0002405 44.0
PYH2_k127_8773564_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 6.616e-214 671.0
PYH2_k127_8773564_1 ThiS family K03636 - - 0.0000000000000000000000000000000002115 134.0
PYH2_k127_8773564_2 NIL - - - 0.00000000000000004445 83.0
PYH2_k127_8801259_0 PFAM transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 577.0
PYH2_k127_8801259_1 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000001341 190.0
PYH2_k127_8848675_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 522.0
PYH2_k127_8848675_1 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000002704 224.0
PYH2_k127_8848675_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000112 177.0
PYH2_k127_8848675_3 GIY-YIG type nucleases (URI domain) K07461 - - 0.0000000000000000000000000000000004973 132.0
PYH2_k127_8848675_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000000002182 98.0
PYH2_k127_8883255_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 535.0
PYH2_k127_8883255_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000004033 86.0
PYH2_k127_8910387_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.278e-319 991.0
PYH2_k127_8929735_0 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 375.0
PYH2_k127_8929735_1 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000004626 144.0
PYH2_k127_8941824_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 460.0
PYH2_k127_8941824_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 320.0
PYH2_k127_8941824_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000001024 247.0
PYH2_k127_8941824_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
PYH2_k127_8941824_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000752 155.0
PYH2_k127_8941824_5 - - - - 0.0000000000000007312 79.0
PYH2_k127_8941824_6 - - - - 0.00000505 58.0
PYH2_k127_8941824_7 Domain of unknown function (DUF4136) - - - 0.000752 48.0
PYH2_k127_8990628_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 403.0
PYH2_k127_8990628_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 343.0
PYH2_k127_8990628_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000002246 154.0
PYH2_k127_8990628_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000003219 148.0
PYH2_k127_8990628_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003067 119.0
PYH2_k127_8990628_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006582 108.0
PYH2_k127_8990628_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002083 105.0
PYH2_k127_8990628_15 Binds to the 23S rRNA K02876 - - 0.00000000000000000001286 94.0
PYH2_k127_8990628_16 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000441 78.0
PYH2_k127_8990628_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 295.0
PYH2_k127_8990628_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001542 237.0
PYH2_k127_8990628_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000001835 236.0
PYH2_k127_8990628_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002186 233.0
PYH2_k127_8990628_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008532 199.0
PYH2_k127_8990628_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000002008 170.0
PYH2_k127_8990628_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000007402 167.0
PYH2_k127_8990628_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000004253 157.0
PYH2_k127_8996181_0 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 578.0
PYH2_k127_8996181_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 561.0
PYH2_k127_8996181_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 361.0
PYH2_k127_8996181_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001525 246.0
PYH2_k127_8996181_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000001087 186.0
PYH2_k127_8996181_5 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000001983 119.0
PYH2_k127_8996181_6 photosynthesis - - - 0.00000000000000000003809 92.0
PYH2_k127_8996181_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000008448 66.0
PYH2_k127_9002702_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000001485 191.0
PYH2_k127_9002702_1 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000007179 192.0
PYH2_k127_9002702_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000001136 135.0
PYH2_k127_903716_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 310.0
PYH2_k127_903716_1 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000001143 99.0
PYH2_k127_903716_2 Thioredoxin-like - - - 0.00000002547 60.0
PYH2_k127_9057620_0 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 594.0
PYH2_k127_9057620_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 449.0
PYH2_k127_9057620_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 431.0
PYH2_k127_9057620_3 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 398.0
PYH2_k127_9057620_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000008584 230.0
PYH2_k127_9057620_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001154 146.0
PYH2_k127_9057620_6 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000009835 140.0
PYH2_k127_9057620_7 - - - - 0.0000000000000007711 79.0
PYH2_k127_9084909_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
PYH2_k127_9084909_1 Protein-disulfide isomerase - - - 0.00000000000000000000000000004849 121.0
PYH2_k127_9084909_2 Prokaryotic cytochrome b561 K00127 - - 0.0000000000002435 72.0
PYH2_k127_9084909_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000004698 52.0
PYH2_k127_9084909_4 DSBA-like thioredoxin domain - - - 0.00002705 49.0
PYH2_k127_9184990_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 2.191e-240 766.0
PYH2_k127_9184990_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 493.0
PYH2_k127_9184990_10 Protein of unknown function (DUF1573) - - - 0.000005509 50.0
PYH2_k127_9184990_11 Protein of unknown function (DUF1573) - - - 0.00002471 48.0
PYH2_k127_9184990_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 462.0
PYH2_k127_9184990_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 445.0
PYH2_k127_9184990_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 346.0
PYH2_k127_9184990_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
PYH2_k127_9184990_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000005059 151.0
PYH2_k127_9184990_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000001198 109.0
PYH2_k127_9184990_8 gas vesicle protein - - - 0.000000000000000000004889 98.0
PYH2_k127_9195441_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 6.128e-320 992.0
PYH2_k127_9195441_1 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 574.0
PYH2_k127_9195441_2 4Fe-4S dicluster domain K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001873 276.0
PYH2_k127_9195441_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000002225 201.0
PYH2_k127_9195441_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000005782 131.0
PYH2_k127_9221398_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.865e-289 897.0
PYH2_k127_9221398_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000001385 201.0
PYH2_k127_9232108_0 UDP binding domain K02474,K13015 - 1.1.1.136 1.409e-274 852.0
PYH2_k127_9232108_1 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000004846 154.0
PYH2_k127_9232108_2 His Kinase A (phosphoacceptor) domain - - - 0.00000007837 63.0
PYH2_k127_924937_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 568.0
PYH2_k127_924937_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009849 243.0
PYH2_k127_924937_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000001177 171.0
PYH2_k127_9284993_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000002369 272.0
PYH2_k127_9284993_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000005795 194.0
PYH2_k127_9284993_2 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000007569 133.0
PYH2_k127_9284993_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000216 114.0
PYH2_k127_9317694_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 5.081e-224 712.0
PYH2_k127_9317694_1 PFAM Major Facilitator Superfamily K08177 - - 1.186e-208 655.0
PYH2_k127_9317694_2 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 428.0
PYH2_k127_9317694_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000002381 225.0
PYH2_k127_9318259_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 541.0
PYH2_k127_9318259_1 Transcriptional regulator, MerR family - - - 0.000000000000000000000001988 106.0
PYH2_k127_943049_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 490.0
PYH2_k127_943049_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 481.0
PYH2_k127_943049_2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 449.0
PYH2_k127_943049_3 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 372.0
PYH2_k127_943049_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 360.0
PYH2_k127_943049_5 - - - - 0.00000000000000000000000001006 112.0
PYH2_k127_943049_6 - - - - 0.0000000000000000000003033 100.0
PYH2_k127_943049_8 Rubrerythrin - - - 0.00001506 49.0
PYH2_k127_952891_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 338.0
PYH2_k127_952891_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000002074 214.0
PYH2_k127_952891_2 efflux transmembrane transporter activity - - - 0.0000000851 61.0
PYH2_k127_965597_0 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 314.0
PYH2_k127_965597_1 PFAM ATP-binding region, ATPase domain protein K02482,K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001126 256.0
PYH2_k127_965597_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000005068 241.0
PYH2_k127_975278_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1008.0
PYH2_k127_975278_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.985e-226 709.0
PYH2_k127_975278_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 573.0
PYH2_k127_975278_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 427.0
PYH2_k127_975278_4 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000001989 189.0
PYH2_k127_975278_5 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000002702 137.0
PYH2_k127_981832_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 548.0
PYH2_k127_981832_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 400.0
PYH2_k127_981832_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 394.0
PYH2_k127_981832_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 260.0
PYH2_k127_981832_5 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000001771 167.0
PYH2_k127_981832_6 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000005258 87.0
PYH2_k127_981832_7 toxin-antitoxin pair type II binding K19159 - - 0.000000007509 60.0
PYH2_k127_981832_8 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000001708 56.0