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Overview

ID MAG03198
Name PYH2_bin.53
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family Villigracilaceae
Genus JBGPQJ01
Species
Assembly information
Completeness (%) 92.11
Contamination (%) 6.7
GC content (%) 55.0
N50 (bp) 26,227
Genome size (bp) 3,968,714

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3526

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1030005_0 BNR/Asp-box repeat - - - 1.893e-213 665.0
PYH2_k127_1030005_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004416 275.0
PYH2_k127_1030005_12 Protein of unknown function (DUF3224) - - - 0.000000000000000000000002437 108.0
PYH2_k127_1030005_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000002502 106.0
PYH2_k127_1030005_14 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000001476 63.0
PYH2_k127_1030005_2 Transposase K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000296 268.0
PYH2_k127_1030005_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005839 231.0
PYH2_k127_1030005_4 transferase activity, transferring acyl groups K03824 - - 0.00000000000000000000000000000000000000000000000000000000001998 210.0
PYH2_k127_1030005_5 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000000000000001873 203.0
PYH2_k127_1030005_6 collagen metabolic process - - - 0.0000000000000000000000000000000000000000000000000001599 191.0
PYH2_k127_1030005_7 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000001973 143.0
PYH2_k127_1030005_8 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000003709 128.0
PYH2_k127_1030005_9 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000004718 115.0
PYH2_k127_1036802_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 380.0
PYH2_k127_1036802_1 Binding-protein-dependent transport system inner membrane component K02025,K10193 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 329.0
PYH2_k127_1036802_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 323.0
PYH2_k127_1045335_0 NADPH-dependent FMN reductase - - - 0.0000000000001622 74.0
PYH2_k127_1045335_1 KR domain - - - 0.00000003294 55.0
PYH2_k127_1080590_1 spore germination K03605 - - 0.0000000000409 65.0
PYH2_k127_1080590_2 PFAM Cyclic nucleotide-binding domain - - - 0.00000007449 60.0
PYH2_k127_1104816_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 289.0
PYH2_k127_1104816_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000002523 222.0
PYH2_k127_1104816_2 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000000000004884 149.0
PYH2_k127_1104816_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000001097 121.0
PYH2_k127_1104816_4 - - - - 0.0000000000000000000000000001197 119.0
PYH2_k127_1104816_5 - - - - 0.0000000000000000000000000003528 128.0
PYH2_k127_1117082_0 ATPase AAA-2 domain protein K03696 - - 0.0 1029.0
PYH2_k127_1117082_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 548.0
PYH2_k127_1117082_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000006428 157.0
PYH2_k127_1117082_11 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000007583 156.0
PYH2_k127_1117082_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000002221 113.0
PYH2_k127_1117082_13 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000002378 63.0
PYH2_k127_1117082_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 489.0
PYH2_k127_1117082_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 455.0
PYH2_k127_1117082_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 314.0
PYH2_k127_1117082_5 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 312.0
PYH2_k127_1117082_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
PYH2_k127_1117082_7 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 289.0
PYH2_k127_1117082_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007872 267.0
PYH2_k127_1117082_9 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000004979 229.0
PYH2_k127_1122411_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 537.0
PYH2_k127_1122411_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 354.0
PYH2_k127_1122411_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 269.0
PYH2_k127_1122411_3 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000001091 202.0
PYH2_k127_1122411_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000001011 56.0
PYH2_k127_1167084_0 PUCC protein - - - 0.00000000000000000000000000000000000004176 153.0
PYH2_k127_1167084_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000006939 141.0
PYH2_k127_1167084_2 - - - - 0.0000000000000001183 86.0
PYH2_k127_1168419_0 (ABC) transporter K06147,K11085 - - 2.699e-250 784.0
PYH2_k127_1168419_1 Selenocysteine-specific translation elongation factor K03833 - - 2.529e-226 717.0
PYH2_k127_1168419_10 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003988 242.0
PYH2_k127_1168419_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000001637 236.0
PYH2_k127_1168419_12 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
PYH2_k127_1168419_13 exodeoxyribonuclease I activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
PYH2_k127_1168419_14 Response regulator, receiver K02487,K03407,K03413,K06596,K11526,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002839 211.0
PYH2_k127_1168419_17 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000003147 104.0
PYH2_k127_1168419_18 - - - - 0.00000002368 61.0
PYH2_k127_1168419_19 Phage integrase family - - - 0.00002937 50.0
PYH2_k127_1168419_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 429.0
PYH2_k127_1168419_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 424.0
PYH2_k127_1168419_4 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 409.0
PYH2_k127_1168419_5 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 339.0
PYH2_k127_1168419_6 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 333.0
PYH2_k127_1168419_7 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 312.0
PYH2_k127_1168419_8 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 308.0
PYH2_k127_1168419_9 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002073 250.0
PYH2_k127_1169510_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000001015 100.0
PYH2_k127_1169510_1 Xylose isomerase-like TIM barrel - - - 0.00000001642 58.0
PYH2_k127_1169510_2 Domain of unknown function (DUF4412) - - - 0.00001816 55.0
PYH2_k127_1218969_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 9.143e-243 765.0
PYH2_k127_1218969_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 6.069e-216 691.0
PYH2_k127_1218969_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000006146 256.0
PYH2_k127_1218969_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002939 247.0
PYH2_k127_1218969_12 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
PYH2_k127_1218969_13 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.0000000000000000000000000000000000000000000000000000002434 202.0
PYH2_k127_1218969_14 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000009652 198.0
PYH2_k127_1218969_15 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000001367 153.0
PYH2_k127_1218969_16 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000009559 147.0
PYH2_k127_1218969_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000003292 139.0
PYH2_k127_1218969_18 Methyltransferase type 11 - - - 0.000000000000000000000000000000005166 135.0
PYH2_k127_1218969_19 - - - - 0.00000000000000000000000004045 115.0
PYH2_k127_1218969_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.115e-206 653.0
PYH2_k127_1218969_20 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000008728 117.0
PYH2_k127_1218969_21 binding domain protein K07138 - - 0.0000009868 53.0
PYH2_k127_1218969_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.728e-200 633.0
PYH2_k127_1218969_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 504.0
PYH2_k127_1218969_5 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 497.0
PYH2_k127_1218969_6 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 397.0
PYH2_k127_1218969_7 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 313.0
PYH2_k127_1218969_8 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 295.0
PYH2_k127_1218969_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000174 273.0
PYH2_k127_12466_0 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
PYH2_k127_12466_1 pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000057 107.0
PYH2_k127_12466_2 Peptidase family M23 - - - 0.0000000000000003392 84.0
PYH2_k127_12466_4 UbiA prenyltransferase family K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.00000003263 64.0
PYH2_k127_1298005_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1026.0
PYH2_k127_1298005_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 529.0
PYH2_k127_1298005_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
PYH2_k127_1298005_11 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000001144 229.0
PYH2_k127_1298005_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000003761 193.0
PYH2_k127_1298005_13 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000001955 189.0
PYH2_k127_1298005_14 alpha-ribazole phosphatase activity K01834,K15634,K22306 - 3.1.3.85,5.4.2.11,5.4.2.12 0.0000000000000000000000000000000000000000000005663 174.0
PYH2_k127_1298005_15 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000000000001169 167.0
PYH2_k127_1298005_16 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000004731 170.0
PYH2_k127_1298005_17 methyltransferase - - - 0.000000000000000000000000000000000000000001285 166.0
PYH2_k127_1298005_18 transcription factor binding - - - 0.0000000000000000000000000000000000000007679 151.0
PYH2_k127_1298005_19 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000001531 132.0
PYH2_k127_1298005_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 509.0
PYH2_k127_1298005_20 NUDIX domain - - - 0.000000000000000000000000000007585 124.0
PYH2_k127_1298005_21 Belongs to the P(II) protein family - - - 0.0000000000000000000000000003091 117.0
PYH2_k127_1298005_24 arsR family K21903 - - 0.000000000000000000003122 96.0
PYH2_k127_1298005_25 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000007931 100.0
PYH2_k127_1298005_26 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000003075 97.0
PYH2_k127_1298005_27 methyltransferase activity - - - 0.00000000000000003665 89.0
PYH2_k127_1298005_28 - - - - 0.00000000000004866 77.0
PYH2_k127_1298005_29 PFAM Sterol-binding domain protein - - - 0.00000002091 59.0
PYH2_k127_1298005_30 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 0.0000001833 63.0
PYH2_k127_1298005_31 O-Methyltransferase - - - 0.00001949 49.0
PYH2_k127_1298005_32 - - - - 0.00005092 53.0
PYH2_k127_1298005_33 - - - - 0.0006339 46.0
PYH2_k127_1298005_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 423.0
PYH2_k127_1298005_5 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 349.0
PYH2_k127_1298005_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 348.0
PYH2_k127_1298005_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
PYH2_k127_1298005_8 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 308.0
PYH2_k127_1298005_9 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000222 271.0
PYH2_k127_1367677_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 380.0
PYH2_k127_1367677_1 - - - - 0.00000000000000000000000000000000000000000000000002101 191.0
PYH2_k127_1367677_2 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000003267 178.0
PYH2_k127_1367677_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000001024 74.0
PYH2_k127_1367677_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 0.00000000003867 63.0
PYH2_k127_1370349_0 PFAM homogentisate 12-dioxygenase K00451 - 1.13.11.5 6.972e-200 627.0
PYH2_k127_1370349_1 PFAM fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 299.0
PYH2_k127_1370349_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004145 228.0
PYH2_k127_1370349_3 (ABC) transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000003016 208.0
PYH2_k127_1370349_4 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000006366 145.0
PYH2_k127_137603_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 451.0
PYH2_k127_137603_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 376.0
PYH2_k127_137603_2 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 314.0
PYH2_k127_137603_3 - - - - 0.00000000000000000000000000000000000000000000001037 179.0
PYH2_k127_137603_4 Domain of unknown function (DUF4129) - - - 0.00000000000000000000001158 107.0
PYH2_k127_1380475_0 PFAM NHL repeat containing protein - - - 1.24e-322 1021.0
PYH2_k127_1380475_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 457.0
PYH2_k127_1380475_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 306.0
PYH2_k127_1380475_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 286.0
PYH2_k127_1380475_4 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000003491 261.0
PYH2_k127_1380475_5 - - - - 0.00000000000000000000000000000000000000000000000000001428 191.0
PYH2_k127_1380475_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000009011 173.0
PYH2_k127_1402818_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 2.297e-241 754.0
PYH2_k127_1402818_1 PFAM single-stranded nucleic acid binding R3H domain protein - - - 1.66e-224 708.0
PYH2_k127_1402818_10 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
PYH2_k127_1402818_11 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 396.0
PYH2_k127_1402818_12 Dihydroorotate dehydrogenase K00226,K00254 - 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 332.0
PYH2_k127_1402818_13 'de novo' UMP biosynthetic process K00762,K01591,K13421,K15334 GO:0003674,GO:0003824,GO:0004588,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.1.1.202,2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 306.0
PYH2_k127_1402818_14 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001119 304.0
PYH2_k127_1402818_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007564 271.0
PYH2_k127_1402818_16 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004773 274.0
PYH2_k127_1402818_17 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008099 269.0
PYH2_k127_1402818_18 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005688 268.0
PYH2_k127_1402818_19 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003283 275.0
PYH2_k127_1402818_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 1.944e-208 664.0
PYH2_k127_1402818_20 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003577 261.0
PYH2_k127_1402818_21 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000002661 252.0
PYH2_k127_1402818_22 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002801 252.0
PYH2_k127_1402818_23 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
PYH2_k127_1402818_24 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000004931 245.0
PYH2_k127_1402818_25 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000009861 252.0
PYH2_k127_1402818_26 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000004023 218.0
PYH2_k127_1402818_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000009324 200.0
PYH2_k127_1402818_28 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000001632 192.0
PYH2_k127_1402818_3 Serine carboxypeptidase - - - 1.239e-205 650.0
PYH2_k127_1402818_30 Putative regulatory protein - - - 0.000000000000000000000000000000000000000001107 159.0
PYH2_k127_1402818_31 PFAM regulatory protein GntR HTH K07979 - - 0.0000000000000000000000000000000000002308 146.0
PYH2_k127_1402818_32 Inner membrane component of T3SS, cytoplasmic domain K08372 - - 0.00000000000000000000000000000000009205 151.0
PYH2_k127_1402818_33 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000001285 142.0
PYH2_k127_1402818_34 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000004395 123.0
PYH2_k127_1402818_35 Domain of unknown function (DUF4258) - - - 0.0000000000000003635 79.0
PYH2_k127_1402818_36 Domain of unknown function (DUF1905) - - - 0.000000000000002988 78.0
PYH2_k127_1402818_39 - - - - 0.0000001122 54.0
PYH2_k127_1402818_4 PFAM ABC transporter related K02049,K15555,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 610.0
PYH2_k127_1402818_40 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000002078 56.0
PYH2_k127_1402818_41 - - - - 0.00003869 55.0
PYH2_k127_1402818_5 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 550.0
PYH2_k127_1402818_6 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 536.0
PYH2_k127_1402818_7 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 501.0
PYH2_k127_1402818_8 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 431.0
PYH2_k127_1402818_9 Amidohydrolase family K11540 - 2.1.3.2,3.5.2.3,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 425.0
PYH2_k127_1413798_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1896.0
PYH2_k127_147421_0 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006772 242.0
PYH2_k127_147421_1 cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000001117 156.0
PYH2_k127_147421_2 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000009099 150.0
PYH2_k127_147421_3 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000001308 118.0
PYH2_k127_147421_4 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000006232 61.0
PYH2_k127_147421_5 PKD domain containing protein - - - 0.0001769 49.0
PYH2_k127_1527233_0 Participates in both transcription termination and antitermination K02600 - - 1.845e-218 696.0
PYH2_k127_1527233_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 571.0
PYH2_k127_1527233_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 338.0
PYH2_k127_1527233_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001614 220.0
PYH2_k127_1527233_4 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000000000000000000000000000000000000000000000001754 184.0
PYH2_k127_1527233_5 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000004812 121.0
PYH2_k127_1597791_0 Ferrous iron transport protein B C terminus K04759 - - 5.423e-203 642.0
PYH2_k127_1597791_1 Ferrous iron transport protein B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 419.0
PYH2_k127_1597791_2 iron ion homeostasis K03322,K03709,K04758 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 382.0
PYH2_k127_1597791_3 Belongs to the Pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 314.0
PYH2_k127_1597791_4 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008416 251.0
PYH2_k127_1597791_5 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000007637 167.0
PYH2_k127_1637616_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000005207 160.0
PYH2_k127_1637616_1 Histidine kinase - - - 0.00000002824 62.0
PYH2_k127_1670716_0 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 587.0
PYH2_k127_1670716_1 Formate hydrogenlyase subunit 5 K12142,K14090,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007952 250.0
PYH2_k127_1677734_0 DEAD DEAH box helicase domain protein K06877 - - 3.291e-293 922.0
PYH2_k127_1677734_1 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 406.0
PYH2_k127_1677734_10 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000001102 173.0
PYH2_k127_1677734_11 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000125 140.0
PYH2_k127_1677734_12 PFAM secretion protein HlyD family protein - - - 0.000000000000000000000000000000002116 142.0
PYH2_k127_1677734_13 - - - - 0.00000000000000000000000000000008961 130.0
PYH2_k127_1677734_14 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000004743 100.0
PYH2_k127_1677734_15 Cysteine-rich secretory protein family - - - 0.000000000000000002 98.0
PYH2_k127_1677734_16 PFAM Radical SAM domain protein - - - 0.000000000000003276 87.0
PYH2_k127_1677734_17 - - - - 0.0000000000006749 75.0
PYH2_k127_1677734_18 Transposase - - - 0.0001109 46.0
PYH2_k127_1677734_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 367.0
PYH2_k127_1677734_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 310.0
PYH2_k127_1677734_4 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
PYH2_k127_1677734_5 sugar transporter K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003819 293.0
PYH2_k127_1677734_6 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002319 289.0
PYH2_k127_1677734_7 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 279.0
PYH2_k127_1677734_8 - - - - 0.00000000000000000000000000000000000000000000000000000000004531 214.0
PYH2_k127_1677734_9 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000001119 192.0
PYH2_k127_1807621_0 intracellular signal transduction - - - 0.000000000000000000000000007841 119.0
PYH2_k127_1807621_1 - - - - 0.000000003826 63.0
PYH2_k127_1808027_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0 1157.0
PYH2_k127_1808027_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000007177 191.0
PYH2_k127_1808027_2 - - - - 0.000000000000000000000000000000001437 132.0
PYH2_k127_1808027_3 - - - - 0.00000000000000000000000003479 109.0
PYH2_k127_1808027_4 PFAM Radical SAM domain protein - - - 0.0000000000000000003024 93.0
PYH2_k127_1830658_0 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 5.169e-216 696.0
PYH2_k127_1830658_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 474.0
PYH2_k127_1830658_10 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000008631 235.0
PYH2_k127_1830658_11 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003855 237.0
PYH2_k127_1830658_12 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000004857 237.0
PYH2_k127_1830658_13 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000006372 173.0
PYH2_k127_1830658_14 Cysteine-rich motif following a subset of SET domains - - - 0.00000000000000000000000000005203 122.0
PYH2_k127_1830658_15 - - - - 0.00000000002173 66.0
PYH2_k127_1830658_16 Universal stress protein - - - 0.0000000002861 71.0
PYH2_k127_1830658_17 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000003945 67.0
PYH2_k127_1830658_18 Diguanylate cyclase - - - 0.0002102 53.0
PYH2_k127_1830658_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 329.0
PYH2_k127_1830658_3 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 332.0
PYH2_k127_1830658_4 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 299.0
PYH2_k127_1830658_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 298.0
PYH2_k127_1830658_6 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005798 262.0
PYH2_k127_1830658_7 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002609 254.0
PYH2_k127_1830658_8 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 254.0
PYH2_k127_1830658_9 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
PYH2_k127_1961852_0 Belongs to the glycosyl hydrolase 31 family - - - 9.131e-249 786.0
PYH2_k127_1961852_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.496e-223 709.0
PYH2_k127_1961852_10 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 509.0
PYH2_k127_1961852_11 Na+/H+ antiporter family K03315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 472.0
PYH2_k127_1961852_12 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 444.0
PYH2_k127_1961852_13 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 447.0
PYH2_k127_1961852_14 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 455.0
PYH2_k127_1961852_15 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 426.0
PYH2_k127_1961852_16 PFAM phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 419.0
PYH2_k127_1961852_17 Peptidase family M28 K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 417.0
PYH2_k127_1961852_18 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 364.0
PYH2_k127_1961852_19 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 383.0
PYH2_k127_1961852_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 7.358e-211 681.0
PYH2_k127_1961852_20 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 360.0
PYH2_k127_1961852_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
PYH2_k127_1961852_22 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 345.0
PYH2_k127_1961852_23 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003386 280.0
PYH2_k127_1961852_24 HD domain K18967 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001006 280.0
PYH2_k127_1961852_25 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000222 268.0
PYH2_k127_1961852_26 zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002958 244.0
PYH2_k127_1961852_27 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000003073 248.0
PYH2_k127_1961852_28 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000001322 179.0
PYH2_k127_1961852_29 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000002016 177.0
PYH2_k127_1961852_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.711e-208 668.0
PYH2_k127_1961852_30 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000001167 183.0
PYH2_k127_1961852_31 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000007055 160.0
PYH2_k127_1961852_32 LURP-one-related - - - 0.0000000000000000000000000000000000000000008463 168.0
PYH2_k127_1961852_33 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000118 161.0
PYH2_k127_1961852_34 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000001232 168.0
PYH2_k127_1961852_35 META domain - - - 0.000000000000000000000000000000000000001874 158.0
PYH2_k127_1961852_36 OsmC-like protein - - - 0.0000000000000000000000000000000000002613 146.0
PYH2_k127_1961852_37 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000000000000001984 150.0
PYH2_k127_1961852_38 DGC domain - - - 0.000000000000000000000000000000000003834 149.0
PYH2_k127_1961852_39 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000006297 138.0
PYH2_k127_1961852_4 Amidinotransferase K01478 - 3.5.3.6 2.577e-195 616.0
PYH2_k127_1961852_40 regulatory protein, arsR - - - 0.0000000000000000000000000000000003531 134.0
PYH2_k127_1961852_41 UPF0126 domain - - - 0.00000000000000000000000000000001099 138.0
PYH2_k127_1961852_42 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000003105 117.0
PYH2_k127_1961852_43 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000000002345 108.0
PYH2_k127_1961852_44 DGC domain - - - 0.0000000000000000000000002845 110.0
PYH2_k127_1961852_45 - - - - 0.000000000000000000000003659 107.0
PYH2_k127_1961852_46 DNA-binding transcription factor activity - - - 0.000000000000000000000005396 106.0
PYH2_k127_1961852_47 Putative Fe-S cluster - - - 0.00000000000000000000001233 107.0
PYH2_k127_1961852_48 TIGRFAM redox-active disulfide protein 2 - - - 0.00000000000000000000005779 100.0
PYH2_k127_1961852_49 Protein of unknown function (DUF1641) - - - 0.000000000000000000000314 107.0
PYH2_k127_1961852_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 583.0
PYH2_k127_1961852_50 Mut7-C ubiquitin - - - 0.00000001195 59.0
PYH2_k127_1961852_52 response to heat K03668 - - 0.0001502 51.0
PYH2_k127_1961852_53 redox-active disulfide protein 2 - - - 0.0007801 47.0
PYH2_k127_1961852_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 542.0
PYH2_k127_1961852_7 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 527.0
PYH2_k127_1961852_8 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 524.0
PYH2_k127_1961852_9 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 518.0
PYH2_k127_1981270_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.848e-249 778.0
PYH2_k127_1981270_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.139e-240 752.0
PYH2_k127_1981270_10 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005677 262.0
PYH2_k127_1981270_11 ECF-type riboflavin transporter, S component K16924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
PYH2_k127_1981270_12 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002693 267.0
PYH2_k127_1981270_13 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000007016 228.0
PYH2_k127_1981270_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
PYH2_k127_1981270_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000006209 208.0
PYH2_k127_1981270_16 CYTH domain K05873 - 4.6.1.1 0.0000000000000000000000000000000000000001485 157.0
PYH2_k127_1981270_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000006661 145.0
PYH2_k127_1981270_18 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000000000000000002085 124.0
PYH2_k127_1981270_19 DegV family - - - 0.00000000000000000005347 96.0
PYH2_k127_1981270_2 PFAM ABC transporter related K16786,K16787 - - 6.912e-224 706.0
PYH2_k127_1981270_20 molybdopterin converting factor K03635,K21142 - 2.8.1.12 0.0000000000000003562 80.0
PYH2_k127_1981270_21 VanZ like family - - - 0.000000000001261 72.0
PYH2_k127_1981270_22 PFAM Protein kinase domain - - - 0.00000005678 64.0
PYH2_k127_1981270_23 Thioredoxin-like - - - 0.00004269 48.0
PYH2_k127_1981270_3 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 617.0
PYH2_k127_1981270_4 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 576.0
PYH2_k127_1981270_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 434.0
PYH2_k127_1981270_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
PYH2_k127_1981270_7 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 319.0
PYH2_k127_1981270_8 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 289.0
PYH2_k127_1981270_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004873 269.0
PYH2_k127_1987357_0 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 262.0
PYH2_k127_1987357_1 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000007998 155.0
PYH2_k127_1987357_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain' K04771 GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 0.000004693 58.0
PYH2_k127_1987357_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0001433 53.0
PYH2_k127_2041037_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 4.807e-235 736.0
PYH2_k127_2041037_1 PFAM NMT1 THI5 like domain protein K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 388.0
PYH2_k127_2041037_10 Ferredoxin - - - 0.00000000000000000000005791 99.0
PYH2_k127_2041037_11 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.0000000000000381 76.0
PYH2_k127_2041037_12 VIT family - - - 0.00000000005895 63.0
PYH2_k127_2041037_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 313.0
PYH2_k127_2041037_3 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 292.0
PYH2_k127_2041037_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000172 278.0
PYH2_k127_2041037_5 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000007467 198.0
PYH2_k127_2041037_6 - - - - 0.000000000000000000000000000000000000000000000000019 192.0
PYH2_k127_2041037_7 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000001113 192.0
PYH2_k127_2041037_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000002894 163.0
PYH2_k127_2041037_9 Protein of unknown function (DUF1475) - - - 0.0000000000000000000000000000000000002469 143.0
PYH2_k127_2054905_0 PFAM HhH-GPD family protein K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000198 237.0
PYH2_k127_2054905_2 - - - - 0.000000000002695 71.0
PYH2_k127_2054905_3 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000144 57.0
PYH2_k127_2066603_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1673.0
PYH2_k127_2066603_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 6.681e-277 863.0
PYH2_k127_2066603_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 306.0
PYH2_k127_2066603_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
PYH2_k127_2066603_12 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 289.0
PYH2_k127_2066603_13 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005327 277.0
PYH2_k127_2066603_14 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002714 287.0
PYH2_k127_2066603_15 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002276 256.0
PYH2_k127_2066603_16 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000003595 233.0
PYH2_k127_2066603_17 PFAM ABC transporter K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000001309 223.0
PYH2_k127_2066603_18 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000008619 210.0
PYH2_k127_2066603_19 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000002459 191.0
PYH2_k127_2066603_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 438.0
PYH2_k127_2066603_21 - - - - 0.00000000000000000000000000000000000000000007107 177.0
PYH2_k127_2066603_22 DNA-binding transcription factor activity K15973 - - 0.00000000000000000000000000000000000000003833 156.0
PYH2_k127_2066603_23 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000465 139.0
PYH2_k127_2066603_24 - - - - 0.00000000000000000000000000004453 119.0
PYH2_k127_2066603_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000002859 126.0
PYH2_k127_2066603_26 - - - - 0.0000000000000000000000001719 117.0
PYH2_k127_2066603_27 PFAM DinB family protein - - - 0.0000000000000000000000001882 112.0
PYH2_k127_2066603_28 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000002458 109.0
PYH2_k127_2066603_29 Phosphotransferase enzyme family K17910 - 2.7.1.190 0.000000000000000000000001402 117.0
PYH2_k127_2066603_3 Probable transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 424.0
PYH2_k127_2066603_30 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000001512 120.0
PYH2_k127_2066603_31 TOBE domain - - - 0.000000000000000000000589 96.0
PYH2_k127_2066603_32 cytochrome complex assembly K02200,K04018 - - 0.000000000000000000001009 107.0
PYH2_k127_2066603_33 - - - - 0.000000000000000000127 93.0
PYH2_k127_2066603_35 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000001109 93.0
PYH2_k127_2066603_37 YacP-like NYN domain K06962 - - 0.00000000000007685 77.0
PYH2_k127_2066603_38 PFAM aldo keto reductase - - - 0.00000000005594 63.0
PYH2_k127_2066603_39 lactoylglutathione lyase activity - - - 0.0000000002941 66.0
PYH2_k127_2066603_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 416.0
PYH2_k127_2066603_40 carbohydrate transport K02027 - - 0.00000006393 67.0
PYH2_k127_2066603_42 Zinc finger domain - - - 0.00003991 55.0
PYH2_k127_2066603_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 389.0
PYH2_k127_2066603_6 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 388.0
PYH2_k127_2066603_7 extracellular solute-binding protein, family 1 K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 317.0
PYH2_k127_2066603_8 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 329.0
PYH2_k127_2066603_9 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 308.0
PYH2_k127_2078815_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.467e-198 626.0
PYH2_k127_2078815_1 PFAM SMC domain protein K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 550.0
PYH2_k127_2078815_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 460.0
PYH2_k127_2078815_3 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 429.0
PYH2_k127_2078815_4 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 408.0
PYH2_k127_2078815_5 Peptidase family S51 - - - 0.000000000000000000000000000000000000004586 155.0
PYH2_k127_2078815_6 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000008819 138.0
PYH2_k127_2078815_7 Encoded by - - - 0.00000000000000000001121 108.0
PYH2_k127_208122_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 518.0
PYH2_k127_208122_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000005373 193.0
PYH2_k127_208122_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000006833 158.0
PYH2_k127_208122_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000005162 136.0
PYH2_k127_208122_4 - - - - 0.0000000000000000000000000001618 120.0
PYH2_k127_208122_5 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000001522 76.0
PYH2_k127_208122_6 Hydrolase, alpha beta domain protein - - - 0.000000000031 66.0
PYH2_k127_208122_7 Protein of unknown function (DUF2892) - - - 0.00000005365 56.0
PYH2_k127_208122_8 - - - - 0.00000008725 61.0
PYH2_k127_208122_9 CAAX protease self-immunity - - - 0.0004032 51.0
PYH2_k127_2091630_0 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 435.0
PYH2_k127_2091630_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 357.0
PYH2_k127_2091630_2 Peptidase M1 membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 346.0
PYH2_k127_2091630_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
PYH2_k127_2091630_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000003611 206.0
PYH2_k127_2091630_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000003837 69.0
PYH2_k127_2109132_0 Fibronectin type III-like domain - - - 3.677e-300 934.0
PYH2_k127_2109132_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 2.351e-233 728.0
PYH2_k127_2109132_10 COG NOG14600 non supervised orthologous group - - - 0.000000000000000009392 83.0
PYH2_k127_2109132_11 O-methyltransferase K21460 - 2.1.1.304 0.000000000002222 78.0
PYH2_k127_2109132_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000001465 53.0
PYH2_k127_2109132_13 - - - - 0.0000003093 52.0
PYH2_k127_2109132_14 hydroxymethylglutaryl-CoA reductase (NADPH) activity - - - 0.00002281 51.0
PYH2_k127_2109132_2 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 9.266e-227 710.0
PYH2_k127_2109132_3 beta-galactosidase K12308 - 3.2.1.23 1.367e-219 699.0
PYH2_k127_2109132_4 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 608.0
PYH2_k127_2109132_5 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 580.0
PYH2_k127_2109132_6 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K18916 - 1.1.1.26,1.20.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 395.0
PYH2_k127_2109132_7 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001951 268.0
PYH2_k127_2109132_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
PYH2_k127_2109132_9 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000005533 150.0
PYH2_k127_2133623_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000481 220.0
PYH2_k127_2133623_2 4Fe-4S dicluster domain K18930 - - 0.00000000587 60.0
PYH2_k127_2172466_0 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002712 258.0
PYH2_k127_2172466_1 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000001456 214.0
PYH2_k127_2172466_2 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000007408 168.0
PYH2_k127_2172466_3 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000000000000000000000000002103 126.0
PYH2_k127_2172466_4 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000006239 99.0
PYH2_k127_2207064_0 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000003089 228.0
PYH2_k127_2207064_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.0000000000000000000000000000000195 131.0
PYH2_k127_2207064_2 PFAM TrkA-N domain protein - - - 0.0000000000003462 72.0
PYH2_k127_2220110_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0 1008.0
PYH2_k127_2220110_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 458.0
PYH2_k127_2220110_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000001402 244.0
PYH2_k127_2220110_3 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000004171 188.0
PYH2_k127_2220110_4 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000001675 194.0
PYH2_k127_2220110_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000009344 184.0
PYH2_k127_2220110_6 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.000000000000000000000000000000002436 134.0
PYH2_k127_2220110_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000004648 131.0
PYH2_k127_2223722_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 409.0
PYH2_k127_2223722_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 349.0
PYH2_k127_2223722_2 Methyltransferase FkbM family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
PYH2_k127_2223722_3 -O-antigen K02847,K13009 - - 0.00000000000000000000000000000000000000000000000000000000002008 221.0
PYH2_k127_2223722_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000003373 201.0
PYH2_k127_2223722_5 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000003227 199.0
PYH2_k127_2223722_6 Polysaccharide biosynthesis protein - - - 0.0000000000000000004262 99.0
PYH2_k127_2249330_0 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 578.0
PYH2_k127_2249330_1 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 429.0
PYH2_k127_2249330_12 Pilus assembly protein PilZ - - - 0.0005136 48.0
PYH2_k127_2249330_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 392.0
PYH2_k127_2249330_3 aminopeptidase activity K19701,K19702 - 3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 395.0
PYH2_k127_2249330_4 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 309.0
PYH2_k127_2249330_5 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001527 263.0
PYH2_k127_2249330_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001468 210.0
PYH2_k127_2249330_7 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000002191 190.0
PYH2_k127_2249330_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000001924 169.0
PYH2_k127_2249330_9 Acetyltransferase (GNAT) domain K01246 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 0.00000000000000000000000000000000000000002225 157.0
PYH2_k127_2266531_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.663e-318 983.0
PYH2_k127_2266531_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.274e-294 915.0
PYH2_k127_2266531_10 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058,K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 306.0
PYH2_k127_2266531_11 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 287.0
PYH2_k127_2266531_12 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 287.0
PYH2_k127_2266531_13 EamA-like transporter family - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001911 287.0
PYH2_k127_2266531_14 glycosyl transferase group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001528 286.0
PYH2_k127_2266531_15 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000002101 228.0
PYH2_k127_2266531_16 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000009309 228.0
PYH2_k127_2266531_17 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001693 219.0
PYH2_k127_2266531_18 PFAM Roadblock LC7 family protein K07131 - - 0.000000000000000000000000000000000000000000000000000000000005845 209.0
PYH2_k127_2266531_19 - - - - 0.00000000000000000000000000000000000000002168 156.0
PYH2_k127_2266531_2 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 550.0
PYH2_k127_2266531_20 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000004112 132.0
PYH2_k127_2266531_22 Belongs to the UPF0102 family K07460 - - 0.00000001941 61.0
PYH2_k127_2266531_23 - - - - 0.00003657 46.0
PYH2_k127_2266531_3 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 531.0
PYH2_k127_2266531_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 529.0
PYH2_k127_2266531_5 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 336.0
PYH2_k127_2266531_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 349.0
PYH2_k127_2266531_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 319.0
PYH2_k127_2266531_8 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 322.0
PYH2_k127_2266531_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 308.0
PYH2_k127_2278642_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 2.037e-213 669.0
PYH2_k127_2278642_1 Domain of unknown function DUF87 K06915 - - 3.008e-201 642.0
PYH2_k127_2278642_10 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 367.0
PYH2_k127_2278642_11 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 360.0
PYH2_k127_2278642_13 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 330.0
PYH2_k127_2278642_14 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 330.0
PYH2_k127_2278642_15 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
PYH2_k127_2278642_16 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 291.0
PYH2_k127_2278642_18 polysaccharide biosynthetic process K16694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001442 281.0
PYH2_k127_2278642_19 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000004145 266.0
PYH2_k127_2278642_2 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 594.0
PYH2_k127_2278642_20 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007115 274.0
PYH2_k127_2278642_21 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003098 261.0
PYH2_k127_2278642_22 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
PYH2_k127_2278642_23 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000002126 243.0
PYH2_k127_2278642_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002706 243.0
PYH2_k127_2278642_25 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000000000000000002302 209.0
PYH2_k127_2278642_27 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000001505 195.0
PYH2_k127_2278642_28 - - - - 0.000000000000000000000000000000000000000000000000001079 200.0
PYH2_k127_2278642_29 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000003197 185.0
PYH2_k127_2278642_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 500.0
PYH2_k127_2278642_30 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000003714 188.0
PYH2_k127_2278642_31 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000005833 184.0
PYH2_k127_2278642_32 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567,K01246,K10778 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 0.0000000000000000000000000000000001416 139.0
PYH2_k127_2278642_33 - K13652 - - 0.0000000000000000000000000000000009043 136.0
PYH2_k127_2278642_34 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000003072 139.0
PYH2_k127_2278642_35 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000003332 138.0
PYH2_k127_2278642_36 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.0000000000000000000000000000009268 133.0
PYH2_k127_2278642_37 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000003117 109.0
PYH2_k127_2278642_38 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000006559 112.0
PYH2_k127_2278642_39 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000003442 95.0
PYH2_k127_2278642_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 496.0
PYH2_k127_2278642_40 - - - - 0.0000000000000001537 92.0
PYH2_k127_2278642_41 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000001212 84.0
PYH2_k127_2278642_42 - - - - 0.000009213 52.0
PYH2_k127_2278642_5 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 458.0
PYH2_k127_2278642_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 454.0
PYH2_k127_2278642_7 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 431.0
PYH2_k127_2278642_9 PFAM Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 372.0
PYH2_k127_2324293_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1497.0
PYH2_k127_2324293_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 4.9e-254 797.0
PYH2_k127_2324293_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 591.0
PYH2_k127_2324293_3 lipid binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007198 284.0
PYH2_k127_2324293_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000005618 232.0
PYH2_k127_2324293_5 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
PYH2_k127_2324293_6 LysM domain K02020 - - 0.000000000000000000000000000000000000000000000000000006058 198.0
PYH2_k127_2324293_7 Chloramphenicol phosphotransferase-like protein K02224,K18554 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000004119 146.0
PYH2_k127_2324293_8 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000008097 103.0
PYH2_k127_2328669_0 - - - - 0.00000000000000000000002484 108.0
PYH2_k127_2328669_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000002129 70.0
PYH2_k127_2328669_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000003464 70.0
PYH2_k127_2328669_3 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000001384 62.0
PYH2_k127_2328669_4 PfpI family K05520 - 3.5.1.124 0.0003277 47.0
PYH2_k127_2328669_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0004828 44.0
PYH2_k127_2348433_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.843e-281 877.0
PYH2_k127_2348433_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 7.429e-281 873.0
PYH2_k127_2348433_10 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 337.0
PYH2_k127_2348433_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006642 283.0
PYH2_k127_2348433_12 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005907 252.0
PYH2_k127_2348433_13 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
PYH2_k127_2348433_14 adenosylhomocysteine nucleosidase activity K01239,K01243,K03716 - 3.2.2.1,3.2.2.9,4.1.99.14 0.0000000000000000000000000000000000000000000000000000000002422 210.0
PYH2_k127_2348433_15 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000006449 205.0
PYH2_k127_2348433_16 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000238 184.0
PYH2_k127_2348433_17 Protein of unknown function (DUF1461) - - - 0.00000000000000000000000000000000000000000000000009725 184.0
PYH2_k127_2348433_18 NUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000000000005904 169.0
PYH2_k127_2348433_19 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000009893 159.0
PYH2_k127_2348433_2 Dienelactone hydrolase family - - - 4.089e-269 844.0
PYH2_k127_2348433_20 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001206 111.0
PYH2_k127_2348433_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000004982 106.0
PYH2_k127_2348433_23 AcrB/AcrD/AcrF family - - - 0.000000000000000001857 86.0
PYH2_k127_2348433_25 Endonuclease/Exonuclease/phosphatase family - - - 0.00002636 55.0
PYH2_k127_2348433_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 5.219e-232 725.0
PYH2_k127_2348433_4 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 582.0
PYH2_k127_2348433_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 431.0
PYH2_k127_2348433_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 410.0
PYH2_k127_2348433_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 383.0
PYH2_k127_2348433_8 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 361.0
PYH2_k127_2348433_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 349.0
PYH2_k127_235231_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1587.0
PYH2_k127_235231_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 469.0
PYH2_k127_235231_10 PQQ-like domain - - - 0.000000000000000000000000009117 123.0
PYH2_k127_235231_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000002603 114.0
PYH2_k127_235231_12 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000001849 107.0
PYH2_k127_235231_13 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001947 88.0
PYH2_k127_235231_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000001791 93.0
PYH2_k127_235231_15 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000004664 71.0
PYH2_k127_235231_2 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 427.0
PYH2_k127_235231_3 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 319.0
PYH2_k127_235231_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 271.0
PYH2_k127_235231_5 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003936 269.0
PYH2_k127_235231_6 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000003061 234.0
PYH2_k127_235231_7 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000002684 190.0
PYH2_k127_235231_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000000001868 148.0
PYH2_k127_235231_9 Protein of unknown function (DUF952) K00799 - 2.5.1.18 0.00000000000000000000000000000002505 130.0
PYH2_k127_2359927_0 Sulfatase K01130 - 3.1.6.1 0.0 1082.0
PYH2_k127_2359927_1 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 405.0
PYH2_k127_2359927_2 trisaccharide binding K03556 - - 0.000000000000000000000000003098 120.0
PYH2_k127_237613_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 430.0
PYH2_k127_237613_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 424.0
PYH2_k127_237613_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000111 162.0
PYH2_k127_237613_11 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000003534 103.0
PYH2_k127_237613_12 metallocarboxypeptidase activity K14054 - - 0.0000000000000089 85.0
PYH2_k127_237613_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00001374 53.0
PYH2_k127_237613_2 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 396.0
PYH2_k127_237613_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 391.0
PYH2_k127_237613_4 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 366.0
PYH2_k127_237613_5 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 341.0
PYH2_k127_237613_6 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 330.0
PYH2_k127_237613_7 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 297.0
PYH2_k127_237613_8 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
PYH2_k127_237613_9 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000006766 179.0
PYH2_k127_2390922_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001409 268.0
PYH2_k127_2390922_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000045 250.0
PYH2_k127_2390922_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000001406 250.0
PYH2_k127_2390922_3 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000007553 214.0
PYH2_k127_2390922_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000002085 181.0
PYH2_k127_2390922_5 beta-galactosidase activity K01190,K01197,K01206,K17624 - 3.2.1.23,3.2.1.35,3.2.1.51,3.2.1.97 0.0000000000000000000000000000000000000004902 166.0
PYH2_k127_2390922_6 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000001009 127.0
PYH2_k127_2390922_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000001298 120.0
PYH2_k127_2390922_8 Beta-lactamase K18988 - 3.4.16.4 0.000000000907 70.0
PYH2_k127_2390922_9 Glycosyltransferase family 87 - - - 0.00007762 55.0
PYH2_k127_2402671_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 544.0
PYH2_k127_2402671_1 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 396.0
PYH2_k127_2402671_2 HTH-type transcriptional regulator (heavy metal copper efflux protein) - - - 0.000000000004189 71.0
PYH2_k127_2493893_0 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000147 179.0
PYH2_k127_2493893_1 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000000000000000000001052 169.0
PYH2_k127_2537365_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1277.0
PYH2_k127_2537365_1 Dehydrogenase E1 component K00615 - 2.2.1.1 2.343e-306 958.0
PYH2_k127_2537365_10 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 329.0
PYH2_k127_2537365_11 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 322.0
PYH2_k127_2537365_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 330.0
PYH2_k127_2537365_13 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
PYH2_k127_2537365_14 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 236.0
PYH2_k127_2537365_15 Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions K02635 GO:0005575,GO:0005622,GO:0005623,GO:0009512,GO:0009579,GO:0016020,GO:0032991,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464,GO:0070069 - 0.00000000000000000000000000000000000000000000000000000000000001623 226.0
PYH2_k127_2537365_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001058 217.0
PYH2_k127_2537365_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000002147 204.0
PYH2_k127_2537365_18 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000006021 197.0
PYH2_k127_2537365_19 regulatory protein LysR K21703 - - 0.000000000000000000000000000000000000000000000000000007337 201.0
PYH2_k127_2537365_2 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 7.503e-237 739.0
PYH2_k127_2537365_20 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000001096 173.0
PYH2_k127_2537365_21 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000009521 151.0
PYH2_k127_2537365_22 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000001369 142.0
PYH2_k127_2537365_23 zinc-ribbon domain - - - 0.000000000000000000000000000000003426 134.0
PYH2_k127_2537365_24 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000008365 106.0
PYH2_k127_2537365_25 Peptidase family S58 - - - 0.00000000000000000000001056 102.0
PYH2_k127_2537365_26 Rieske 2Fe-2S - - - 0.000000000000000000002036 100.0
PYH2_k127_2537365_27 - - - - 0.000000000000000000003348 102.0
PYH2_k127_2537365_28 Fe-S oxidoreductase - - - 0.00000000000000004841 87.0
PYH2_k127_2537365_29 Cytochrome b subunit of the bc complex K02637 - - 0.00000000000003709 79.0
PYH2_k127_2537365_3 Immune inhibitor A peptidase M6 - - - 5.255e-235 745.0
PYH2_k127_2537365_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 5.042e-212 678.0
PYH2_k127_2537365_5 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 544.0
PYH2_k127_2537365_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 433.0
PYH2_k127_2537365_8 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 419.0
PYH2_k127_2537365_9 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
PYH2_k127_2566717_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 490.0
PYH2_k127_2566717_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 466.0
PYH2_k127_2566717_2 PFAM peptidase, membrane zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
PYH2_k127_2566717_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000004815 186.0
PYH2_k127_2566717_4 lysyltransferase activity K07027 - - 0.000000000004667 70.0
PYH2_k127_2649596_0 metal-dependent phosphohydrolase, HD sub domain K07037 - - 1.658e-212 681.0
PYH2_k127_2649596_1 PFAM type II secretion system protein E K02283 - - 2.999e-202 637.0
PYH2_k127_2649596_10 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 237.0
PYH2_k127_2649596_11 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
PYH2_k127_2649596_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000107 202.0
PYH2_k127_2649596_13 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000001818 175.0
PYH2_k127_2649596_14 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000001407 170.0
PYH2_k127_2649596_15 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000002961 165.0
PYH2_k127_2649596_16 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000007324 168.0
PYH2_k127_2649596_17 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000001406 149.0
PYH2_k127_2649596_18 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000004185 134.0
PYH2_k127_2649596_19 Thioredoxin - - - 0.00000000000000000000000000000001767 136.0
PYH2_k127_2649596_2 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 555.0
PYH2_k127_2649596_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000004393 115.0
PYH2_k127_2649596_21 - - - - 0.00000000000000000002779 93.0
PYH2_k127_2649596_22 transposase activity K07483,K07497 - - 0.0000000000000006474 81.0
PYH2_k127_2649596_23 Transposase and inactivated derivatives K07497 - - 0.000000000000001437 80.0
PYH2_k127_2649596_25 4-vinyl reductase, 4VR K07013,K17763 - - 0.000000002196 67.0
PYH2_k127_2649596_3 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 366.0
PYH2_k127_2649596_4 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 359.0
PYH2_k127_2649596_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 365.0
PYH2_k127_2649596_6 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 338.0
PYH2_k127_2649596_7 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
PYH2_k127_2649596_8 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 277.0
PYH2_k127_2649596_9 Belongs to the glycosyl hydrolase 18 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002628 279.0
PYH2_k127_2650061_0 Pyridoxal-phosphate dependent enzyme - - - 8.923e-237 740.0
PYH2_k127_2650061_1 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 4.88e-225 704.0
PYH2_k127_2650061_10 Belongs to the 'phage' integrase family - - - 0.000000000000000000003031 93.0
PYH2_k127_2650061_12 - - - - 0.000000000000001256 82.0
PYH2_k127_2650061_2 PFAM carboxyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 561.0
PYH2_k127_2650061_3 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 538.0
PYH2_k127_2650061_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 500.0
PYH2_k127_2650061_5 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000479 185.0
PYH2_k127_2650061_6 Protein conserved in bacteria - - - 0.000000000000000000000000000005977 126.0
PYH2_k127_2650061_7 PFAM biotin lipoyl attachment domain-containing protein - - - 0.000000000000000000000000001852 117.0
PYH2_k127_2650061_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000006533 125.0
PYH2_k127_2650061_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000018 117.0
PYH2_k127_266602_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1419.0
PYH2_k127_266602_1 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 453.0
PYH2_k127_266602_2 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 398.0
PYH2_k127_266602_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001055 254.0
PYH2_k127_266602_4 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000005266 235.0
PYH2_k127_266602_5 PIN domain - - - 0.000000000000000000000000000000000000006986 149.0
PYH2_k127_266602_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000659 102.0
PYH2_k127_266602_7 PIN domain - - - 0.0000000000000000000158 96.0
PYH2_k127_266602_8 SpoVT / AbrB like domain - - - 0.0001312 47.0
PYH2_k127_2676087_0 PFAM UvrD REP helicase - - - 1.644e-269 844.0
PYH2_k127_2676087_1 AAA domain - - - 2.293e-236 744.0
PYH2_k127_2687883_0 penicillin amidase K01434 - 3.5.1.11 1.17e-309 971.0
PYH2_k127_2687883_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 1.422e-201 639.0
PYH2_k127_2687883_10 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000004715 148.0
PYH2_k127_2687883_12 Transcriptional regulator - - - 0.000000000001222 76.0
PYH2_k127_2687883_13 - - - - 0.00001194 55.0
PYH2_k127_2687883_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 549.0
PYH2_k127_2687883_3 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 439.0
PYH2_k127_2687883_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 415.0
PYH2_k127_2687883_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 330.0
PYH2_k127_2687883_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 324.0
PYH2_k127_2687883_7 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002276 271.0
PYH2_k127_2687883_8 helix_turn_helix, Lux Regulon K07694,K11618 - - 0.000000000000000000000000000000000000000000000001192 181.0
PYH2_k127_2687883_9 domain, Protein - - - 0.0000000000000000000000000000000000001976 154.0
PYH2_k127_2738034_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 4.965e-236 736.0
PYH2_k127_2738034_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000908 72.0
PYH2_k127_275472_0 Belongs to the peptidase S41A family - - - 5.933e-246 784.0
PYH2_k127_275472_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 534.0
PYH2_k127_275472_10 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000002827 148.0
PYH2_k127_275472_11 enzyme of poly-gamma-glutamate biosynthesis (capsule formation) K07282 - - 0.00000000000000000000000000000000000003673 156.0
PYH2_k127_275472_12 Transposase DDE domain - - - 0.000000000000000000000000000000000001238 145.0
PYH2_k127_275472_13 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000001597 134.0
PYH2_k127_275472_14 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000006825 126.0
PYH2_k127_275472_15 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000001255 135.0
PYH2_k127_275472_18 PFAM Transposase DDE domain - - - 0.0000000000000000006041 87.0
PYH2_k127_275472_2 DUF3160 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 539.0
PYH2_k127_275472_20 ubiquitin binding K17987 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708 - 0.0000000000001002 84.0
PYH2_k127_275472_22 ubiquitin-associated (UBA) TS-N domain-containing protein octicosapeptide Phox Bemp1 (PB1) domain-containing protein K17987 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708 - 0.00000003775 66.0
PYH2_k127_275472_23 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000005312 50.0
PYH2_k127_275472_24 PFAM Transposase DDE domain - - - 0.00001324 50.0
PYH2_k127_275472_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 447.0
PYH2_k127_275472_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 339.0
PYH2_k127_275472_5 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 340.0
PYH2_k127_275472_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003893 289.0
PYH2_k127_275472_7 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001032 282.0
PYH2_k127_275472_8 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000482 271.0
PYH2_k127_275472_9 YoaP-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
PYH2_k127_2774393_0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 439.0
PYH2_k127_2774393_1 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.0000000000000000000005945 99.0
PYH2_k127_2774393_2 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000003046 94.0
PYH2_k127_2774393_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000004345 85.0
PYH2_k127_2781835_0 histidine kinase A domain protein - - - 0.0 1319.0
PYH2_k127_2781835_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.427e-271 840.0
PYH2_k127_2781835_10 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 404.0
PYH2_k127_2781835_11 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 393.0
PYH2_k127_2781835_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 389.0
PYH2_k127_2781835_13 Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 381.0
PYH2_k127_2781835_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 341.0
PYH2_k127_2781835_15 TIGRFAM small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 307.0
PYH2_k127_2781835_16 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 316.0
PYH2_k127_2781835_17 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000001345 253.0
PYH2_k127_2781835_18 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000002022 241.0
PYH2_k127_2781835_19 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000000000000000000000000000001103 201.0
PYH2_k127_2781835_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 9.769e-242 755.0
PYH2_k127_2781835_20 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000000000000000001585 160.0
PYH2_k127_2781835_22 CAAX protease self-immunity - - - 0.0000000000000000000000000000004651 125.0
PYH2_k127_2781835_23 Glycosyl hydrolases family 25 K07273 - - 0.000000000000000000000000000003129 132.0
PYH2_k127_2781835_24 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000004437 126.0
PYH2_k127_2781835_25 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000004147 121.0
PYH2_k127_2781835_26 single-species biofilm formation K01790,K03806,K06175 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 3.5.1.28,5.1.3.13,5.4.99.26 0.0000000000000000000000002319 109.0
PYH2_k127_2781835_27 CAAX protease self-immunity - - - 0.000000000000000001125 91.0
PYH2_k127_2781835_28 Domain of unknown function (DUF4870) - - - 0.00000000000001601 78.0
PYH2_k127_2781835_3 uridine kinase K00876 - 2.7.1.48 3.309e-239 752.0
PYH2_k127_2781835_31 FecR protein - - - 0.00001512 56.0
PYH2_k127_2781835_32 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00006612 46.0
PYH2_k127_2781835_33 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0002123 47.0
PYH2_k127_2781835_4 Hexapeptide repeat of succinyl-transferase - - - 1.123e-202 637.0
PYH2_k127_2781835_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 598.0
PYH2_k127_2781835_6 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 538.0
PYH2_k127_2781835_7 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 466.0
PYH2_k127_2781835_8 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 413.0
PYH2_k127_2781835_9 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 406.0
PYH2_k127_2796984_0 PFAM ABC transporter transmembrane region - - - 1.976e-209 667.0
PYH2_k127_2796984_1 ABC transporter, transmembrane region K06147 - - 5.083e-205 653.0
PYH2_k127_2796984_2 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 313.0
PYH2_k127_2796984_3 PFAM Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005619 267.0
PYH2_k127_2796984_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002797 258.0
PYH2_k127_2796984_6 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000001247 96.0
PYH2_k127_2796984_7 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000001201 67.0
PYH2_k127_280362_0 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 453.0
PYH2_k127_280362_1 FAD dependent oxidoreductase K21833 - - 0.00000006804 55.0
PYH2_k127_280735_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 372.0
PYH2_k127_280735_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 355.0
PYH2_k127_280735_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000008395 75.0
PYH2_k127_2829716_0 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 334.0
PYH2_k127_2829716_1 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003528 285.0
PYH2_k127_2829716_2 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 267.0
PYH2_k127_2867429_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 508.0
PYH2_k127_2867429_1 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 348.0
PYH2_k127_2867429_2 DeoR C terminal sensor domain K02081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
PYH2_k127_2867429_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000002916 187.0
PYH2_k127_2867429_4 SIS domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000003472 178.0
PYH2_k127_2867429_5 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000003042 152.0
PYH2_k127_2867429_6 Phosphotransferase enzyme family - - - 0.0000000000002154 81.0
PYH2_k127_2867429_7 Magnesium chelatase, subunit ChlI K07391 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000003064 60.0
PYH2_k127_2891895_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.516e-298 939.0
PYH2_k127_2891895_1 Heat shock 70 kDa protein K04043 - - 9.631e-294 912.0
PYH2_k127_2891895_10 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 440.0
PYH2_k127_2891895_11 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 406.0
PYH2_k127_2891895_12 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
PYH2_k127_2891895_13 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 386.0
PYH2_k127_2891895_14 peptidase M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 388.0
PYH2_k127_2891895_15 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 374.0
PYH2_k127_2891895_16 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 362.0
PYH2_k127_2891895_17 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 350.0
PYH2_k127_2891895_18 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 341.0
PYH2_k127_2891895_19 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 310.0
PYH2_k127_2891895_2 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 3.814e-290 910.0
PYH2_k127_2891895_20 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000072 264.0
PYH2_k127_2891895_21 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000009484 246.0
PYH2_k127_2891895_22 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000004777 235.0
PYH2_k127_2891895_23 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000001558 236.0
PYH2_k127_2891895_24 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000007471 222.0
PYH2_k127_2891895_25 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000002138 211.0
PYH2_k127_2891895_27 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000007652 186.0
PYH2_k127_2891895_28 Histidine kinase - - - 0.000000000000000000000000000000000000000000005756 178.0
PYH2_k127_2891895_29 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000005873 171.0
PYH2_k127_2891895_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.189e-280 884.0
PYH2_k127_2891895_30 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000005927 168.0
PYH2_k127_2891895_32 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003277 139.0
PYH2_k127_2891895_33 integral membrane protein - - - 0.0000000000000000000000000000001377 129.0
PYH2_k127_2891895_34 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000006759 120.0
PYH2_k127_2891895_35 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000001319 109.0
PYH2_k127_2891895_36 Domain of unknown function DUF11 - - - 0.0000000000000000001496 95.0
PYH2_k127_2891895_37 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000001804 85.0
PYH2_k127_2891895_39 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000005132 61.0
PYH2_k127_2891895_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.982e-270 850.0
PYH2_k127_2891895_41 Conserved repeat - - - 0.00003569 49.0
PYH2_k127_2891895_42 regulator of chromosome condensation, RCC1 - - - 0.0006591 45.0
PYH2_k127_2891895_5 Endoribonuclease that initiates mRNA decay K18682 - - 7.492e-226 709.0
PYH2_k127_2891895_6 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 482.0
PYH2_k127_2891895_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 482.0
PYH2_k127_2891895_8 Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 473.0
PYH2_k127_2891895_9 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 468.0
PYH2_k127_2896529_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1108.0
PYH2_k127_2896529_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.228e-274 854.0
PYH2_k127_2896529_10 PFAM purine or other phosphorylase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 351.0
PYH2_k127_2896529_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 352.0
PYH2_k127_2896529_12 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 339.0
PYH2_k127_2896529_13 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 339.0
PYH2_k127_2896529_14 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
PYH2_k127_2896529_15 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 310.0
PYH2_k127_2896529_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 312.0
PYH2_k127_2896529_17 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 316.0
PYH2_k127_2896529_18 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 282.0
PYH2_k127_2896529_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000001692 269.0
PYH2_k127_2896529_2 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 1.072e-245 771.0
PYH2_k127_2896529_20 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004359 265.0
PYH2_k127_2896529_21 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
PYH2_k127_2896529_23 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000002955 226.0
PYH2_k127_2896529_24 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000005289 232.0
PYH2_k127_2896529_25 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000003603 211.0
PYH2_k127_2896529_26 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000004915 196.0
PYH2_k127_2896529_27 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000003442 194.0
PYH2_k127_2896529_28 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000000000006925 189.0
PYH2_k127_2896529_29 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000004189 192.0
PYH2_k127_2896529_3 Radical_SAM C-terminal domain K07739 - 2.3.1.48 6.298e-242 758.0
PYH2_k127_2896529_30 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000005713 188.0
PYH2_k127_2896529_31 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000821 184.0
PYH2_k127_2896529_32 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000006094 178.0
PYH2_k127_2896529_33 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000001111 180.0
PYH2_k127_2896529_34 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000119 181.0
PYH2_k127_2896529_35 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000001302 169.0
PYH2_k127_2896529_36 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000005774 163.0
PYH2_k127_2896529_37 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000000000000000000000000000002175 160.0
PYH2_k127_2896529_38 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000001803 132.0
PYH2_k127_2896529_39 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000001939 123.0
PYH2_k127_2896529_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K01214 - 2.7.7.27,3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 554.0
PYH2_k127_2896529_40 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001641 109.0
PYH2_k127_2896529_41 PFAM HD domain - - - 0.000000000000000000000003176 103.0
PYH2_k127_2896529_42 - - - - 0.000000000000000000000005454 113.0
PYH2_k127_2896529_43 COG0675 Transposase and inactivated derivatives K07496 - - 0.000000000000000000004278 98.0
PYH2_k127_2896529_44 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000423 102.0
PYH2_k127_2896529_46 Pfam:DUF385 - - - 0.00000000000000005546 87.0
PYH2_k127_2896529_48 Single-strand binding protein family K03111 - - 0.000000000000001318 79.0
PYH2_k127_2896529_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 484.0
PYH2_k127_2896529_51 - - - - 0.00000000003529 66.0
PYH2_k127_2896529_52 CoA-substrate-specific enzyme activase - - - 0.000000002666 59.0
PYH2_k127_2896529_53 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000001687 59.0
PYH2_k127_2896529_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 460.0
PYH2_k127_2896529_7 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 429.0
PYH2_k127_2896529_8 Phosphotransferase enzyme family K18844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 430.0
PYH2_k127_2896529_9 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 405.0
PYH2_k127_2900421_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 380.0
PYH2_k127_2900421_1 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000254 211.0
PYH2_k127_2900421_2 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000136 173.0
PYH2_k127_2916279_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.477e-290 927.0
PYH2_k127_2916279_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 443.0
PYH2_k127_2916279_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 348.0
PYH2_k127_2916279_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000006508 241.0
PYH2_k127_2916279_4 PFAM Roadblock LC7 family protein K07131 - - 0.000000000000000000000000000000000000000000000000002175 184.0
PYH2_k127_2916279_5 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000002104 116.0
PYH2_k127_2916279_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00001359 48.0
PYH2_k127_2986725_0 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 574.0
PYH2_k127_2986725_1 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000000000000000000001204 201.0
PYH2_k127_2986725_2 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000000009765 145.0
PYH2_k127_2986725_3 OsmC-like protein K07397 - - 0.00000000000000000000000000000000003327 138.0
PYH2_k127_2986725_5 Protein of unknown function (DUF541) K09807 - - 0.00000000000000003116 91.0
PYH2_k127_2986725_6 Domain of unknown function DUF302 - - - 0.00000000000000004441 83.0
PYH2_k127_2997153_0 Putative modulator of DNA gyrase K03568 - - 1.051e-243 759.0
PYH2_k127_2997153_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 7.064e-216 676.0
PYH2_k127_2997153_10 ABC transporter K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 333.0
PYH2_k127_2997153_11 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 323.0
PYH2_k127_2997153_12 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 320.0
PYH2_k127_2997153_13 ATP-dependent transcriptional regulator K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 316.0
PYH2_k127_2997153_14 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 304.0
PYH2_k127_2997153_15 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 294.0
PYH2_k127_2997153_16 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001951 274.0
PYH2_k127_2997153_17 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000047 253.0
PYH2_k127_2997153_18 DNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000002817 226.0
PYH2_k127_2997153_19 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000003813 214.0
PYH2_k127_2997153_2 metallopeptidase activity - - - 7.359e-196 620.0
PYH2_k127_2997153_20 lipid binding - - - 0.00000000000000000000000000000000000000000000000000003815 198.0
PYH2_k127_2997153_21 LysM domain - - - 0.0000000000000000000000000000000000000000000000002601 186.0
PYH2_k127_2997153_22 GAF domain - - - 0.000000000000000000000000000000000000000000000518 182.0
PYH2_k127_2997153_23 - - - - 0.0000000000000000000000000000000000000006626 160.0
PYH2_k127_2997153_24 response to pH - - - 0.00000000000000000000000000000000000003308 149.0
PYH2_k127_2997153_25 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000007861 137.0
PYH2_k127_2997153_26 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000002591 147.0
PYH2_k127_2997153_27 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000003657 118.0
PYH2_k127_2997153_28 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000008781 115.0
PYH2_k127_2997153_29 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000006866 106.0
PYH2_k127_2997153_3 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.959e-195 613.0
PYH2_k127_2997153_30 Polymer-forming cytoskeletal - - - 0.000000000000000000000188 112.0
PYH2_k127_2997153_31 - - - - 0.00000000000000000001208 96.0
PYH2_k127_2997153_33 WD40-like Beta Propeller Repeat K03641 - - 0.000000000004397 80.0
PYH2_k127_2997153_34 - - - - 0.00000000001836 68.0
PYH2_k127_2997153_35 - - - - 0.0000000001971 70.0
PYH2_k127_2997153_37 META domain - - - 0.000000003922 70.0
PYH2_k127_2997153_38 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000005713 68.0
PYH2_k127_2997153_39 SMART Parallel beta-helix repeat - - - 0.00000001576 68.0
PYH2_k127_2997153_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 627.0
PYH2_k127_2997153_40 Protein of unknown function DUF86 - - - 0.0000001528 55.0
PYH2_k127_2997153_41 Tetratricopeptide TPR_2 repeat protein - - - 0.0000002108 64.0
PYH2_k127_2997153_42 Protein of unknown function DUF86 - - - 0.0000005215 51.0
PYH2_k127_2997153_43 Histidine kinase - - - 0.000001963 51.0
PYH2_k127_2997153_44 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000008986 57.0
PYH2_k127_2997153_45 Domain of unknown function DUF11 - - - 0.00003559 57.0
PYH2_k127_2997153_46 Bacterial PH domain - - - 0.0002229 48.0
PYH2_k127_2997153_47 membrane protein of uknown function UCP014873 - - - 0.0003889 50.0
PYH2_k127_2997153_5 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 589.0
PYH2_k127_2997153_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 567.0
PYH2_k127_2997153_7 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 403.0
PYH2_k127_2997153_8 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 410.0
PYH2_k127_2997153_9 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 368.0
PYH2_k127_3068682_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1178.0
PYH2_k127_3068682_1 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 3.661e-294 923.0
PYH2_k127_3068682_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 320.0
PYH2_k127_3068682_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 299.0
PYH2_k127_3068682_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 293.0
PYH2_k127_3068682_13 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000003215 220.0
PYH2_k127_3068682_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000135 215.0
PYH2_k127_3068682_15 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000009819 187.0
PYH2_k127_3068682_16 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000001283 174.0
PYH2_k127_3068682_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000001262 105.0
PYH2_k127_3068682_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 7.64e-216 689.0
PYH2_k127_3068682_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 6.494e-199 632.0
PYH2_k127_3068682_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 6.24e-198 623.0
PYH2_k127_3068682_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 7.341e-197 621.0
PYH2_k127_3068682_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 569.0
PYH2_k127_3068682_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 548.0
PYH2_k127_3068682_8 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 524.0
PYH2_k127_3068682_9 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 515.0
PYH2_k127_3071725_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 2.856e-225 704.0
PYH2_k127_3071725_1 PFAM D-galactarate dehydratase Altronate hydrolase K16846 - 4.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 515.0
PYH2_k127_3071725_2 amidinotransferase K00613 - 2.1.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 481.0
PYH2_k127_3071725_3 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 406.0
PYH2_k127_3071725_4 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 396.0
PYH2_k127_3071725_5 Metallopeptidase family M24 K18829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 365.0
PYH2_k127_3071725_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004085 267.0
PYH2_k127_3071725_7 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 231.0
PYH2_k127_3071725_8 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000002951 230.0
PYH2_k127_3071725_9 sulfolactate sulfo-lyase activity K01685,K16845 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7,4.4.1.24 0.000000000000000000000004867 105.0
PYH2_k127_3093626_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 5.218e-261 809.0
PYH2_k127_3093626_1 PQQ-like domain K05889,K12132 - 1.1.2.6,2.7.11.1 5.724e-225 708.0
PYH2_k127_3093626_10 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 453.0
PYH2_k127_3093626_11 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 417.0
PYH2_k127_3093626_12 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 384.0
PYH2_k127_3093626_13 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 382.0
PYH2_k127_3093626_14 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 366.0
PYH2_k127_3093626_15 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 322.0
PYH2_k127_3093626_16 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
PYH2_k127_3093626_17 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 295.0
PYH2_k127_3093626_18 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
PYH2_k127_3093626_19 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003769 264.0
PYH2_k127_3093626_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 3.027e-220 692.0
PYH2_k127_3093626_20 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009245 262.0
PYH2_k127_3093626_21 PFAM RNA binding S1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006167 224.0
PYH2_k127_3093626_22 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000000000000006976 206.0
PYH2_k127_3093626_23 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002391 205.0
PYH2_k127_3093626_24 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000003429 167.0
PYH2_k127_3093626_25 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000000004463 151.0
PYH2_k127_3093626_26 Transcription regulator K03718 - - 0.0000000000000000000000000000000000006186 145.0
PYH2_k127_3093626_28 AI-2E family transporter K11744 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0009372,GO:0009987,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000002551 145.0
PYH2_k127_3093626_29 Pfam:DUF59 - - - 0.000000000000000000000000000000005782 131.0
PYH2_k127_3093626_3 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 627.0
PYH2_k127_3093626_30 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000009127 133.0
PYH2_k127_3093626_31 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000003253 121.0
PYH2_k127_3093626_32 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000001382 128.0
PYH2_k127_3093626_33 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.000000000000000000000005426 106.0
PYH2_k127_3093626_34 SCP-2 sterol transfer family - - - 0.000000000000000000004283 96.0
PYH2_k127_3093626_35 to GP 6723233 - - - 0.0000000005706 65.0
PYH2_k127_3093626_36 - - - - 0.00000003535 63.0
PYH2_k127_3093626_4 TIGRFAM FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 589.0
PYH2_k127_3093626_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 587.0
PYH2_k127_3093626_6 Aminotransferase class-III K15372 - 2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 504.0
PYH2_k127_3093626_7 Psort location Cytoplasmic, score 8.87 K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 487.0
PYH2_k127_3093626_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 486.0
PYH2_k127_3093626_9 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 474.0
PYH2_k127_3097993_0 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 3.042e-320 1003.0
PYH2_k127_3097993_1 Domain of unknown function (DUF5107) - - - 6.643e-275 880.0
PYH2_k127_3097993_10 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 437.0
PYH2_k127_3097993_11 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 417.0
PYH2_k127_3097993_12 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 417.0
PYH2_k127_3097993_13 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 399.0
PYH2_k127_3097993_14 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 393.0
PYH2_k127_3097993_15 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 368.0
PYH2_k127_3097993_16 beta-1,4-mannooligosaccharide phosphorylase K21065 - 3.2.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 348.0
PYH2_k127_3097993_17 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 339.0
PYH2_k127_3097993_18 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 342.0
PYH2_k127_3097993_19 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 335.0
PYH2_k127_3097993_2 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 2.472e-252 795.0
PYH2_k127_3097993_20 Phosphate transporter family protein K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 326.0
PYH2_k127_3097993_21 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 327.0
PYH2_k127_3097993_22 Carbohydrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 336.0
PYH2_k127_3097993_23 Periplasmic binding protein-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002397 269.0
PYH2_k127_3097993_24 ABC transporter permease K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 256.0
PYH2_k127_3097993_25 PFAM ABC transporter related K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
PYH2_k127_3097993_26 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007281 244.0
PYH2_k127_3097993_27 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000273 256.0
PYH2_k127_3097993_28 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000000004283 232.0
PYH2_k127_3097993_29 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000002794 231.0
PYH2_k127_3097993_3 FtsX-like permease family K02004 - - 1.915e-226 734.0
PYH2_k127_3097993_30 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000273 214.0
PYH2_k127_3097993_31 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000007761 217.0
PYH2_k127_3097993_32 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000003538 193.0
PYH2_k127_3097993_33 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000002187 174.0
PYH2_k127_3097993_34 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000001053 166.0
PYH2_k127_3097993_35 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000000002841 169.0
PYH2_k127_3097993_36 transcriptional K03710 - - 0.000000000000000000000000000000000000000001019 165.0
PYH2_k127_3097993_37 phosphatase activity - - - 0.0000000000000000000000000000000000000009578 166.0
PYH2_k127_3097993_38 - - - - 0.00000000000000000000000000000000000004032 161.0
PYH2_k127_3097993_39 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000005603 151.0
PYH2_k127_3097993_4 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 3.06e-217 683.0
PYH2_k127_3097993_40 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000279 156.0
PYH2_k127_3097993_41 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.000000000000000000000000000000000003936 156.0
PYH2_k127_3097993_42 transcriptional regulator, RpiR family - - - 0.000000000000000000000000000191 125.0
PYH2_k127_3097993_43 HAD-hyrolase-like - - - 0.0000000000000000000156 106.0
PYH2_k127_3097993_44 - - - - 0.00000000000000004559 92.0
PYH2_k127_3097993_45 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000002542 77.0
PYH2_k127_3097993_46 Phosphoribulokinase / Uridine kinase family - - - 0.00000000004132 75.0
PYH2_k127_3097993_47 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000002008 63.0
PYH2_k127_3097993_48 Bacterial extracellular solute-binding protein K02027 - - 0.0000003203 63.0
PYH2_k127_3097993_49 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000003052 51.0
PYH2_k127_3097993_5 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 610.0
PYH2_k127_3097993_50 Beta-lactamase superfamily domain - - - 0.00002755 55.0
PYH2_k127_3097993_51 - - - - 0.0005181 51.0
PYH2_k127_3097993_6 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 580.0
PYH2_k127_3097993_7 PFAM N-acylglucosamine 2-epimerase K01787 - 5.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 568.0
PYH2_k127_3097993_8 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 541.0
PYH2_k127_3097993_9 Domain of unknown function (DUF5109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 448.0
PYH2_k127_3163460_0 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 599.0
PYH2_k127_3163460_1 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 513.0
PYH2_k127_3163460_10 cyclic nucleotide binding K10914 - - 0.00000000000000000000000004159 117.0
PYH2_k127_3163460_11 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000000133 98.0
PYH2_k127_3163460_12 iron-sulfur cluster assembly - - - 0.0000000000000000000003187 106.0
PYH2_k127_3163460_13 membrane - - - 0.0000000000000005251 88.0
PYH2_k127_3163460_14 Putative zinc-finger - - - 0.0000000000000008836 79.0
PYH2_k127_3163460_15 - - - - 0.00000000000001895 80.0
PYH2_k127_3163460_16 Thioredoxin-like - - - 0.00003999 49.0
PYH2_k127_3163460_2 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 453.0
PYH2_k127_3163460_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 415.0
PYH2_k127_3163460_4 beta-N-acetylhexosaminidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 398.0
PYH2_k127_3163460_6 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000004576 206.0
PYH2_k127_3163460_7 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000000000000000000000000003251 171.0
PYH2_k127_3163460_8 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000000000000000000004472 174.0
PYH2_k127_3163460_9 - - - - 0.0000000000000000000000000001372 123.0
PYH2_k127_3195920_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 475.0
PYH2_k127_3195920_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.000000000000000000000000000000000000000000000000000006298 200.0
PYH2_k127_3195920_2 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000001316 116.0
PYH2_k127_3195920_3 Beta-lactamase K01286 - 3.4.16.4 0.000000000000007881 83.0
PYH2_k127_325794_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008914 263.0
PYH2_k127_325794_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000009377 211.0
PYH2_k127_325794_2 PFAM transposase, IS4 family protein - - - 0.00000000000000001749 83.0
PYH2_k127_325794_3 Transposase K07492 - - 0.000000000002662 68.0
PYH2_k127_325794_4 PFAM transposase, IS4 family protein - - - 0.000007168 48.0
PYH2_k127_328179_0 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000006513 222.0
PYH2_k127_328179_1 - - - - 0.000000000000000000001474 105.0
PYH2_k127_3338367_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.487e-197 632.0
PYH2_k127_3338367_1 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 556.0
PYH2_k127_3338367_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 283.0
PYH2_k127_3338367_11 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004185 258.0
PYH2_k127_3338367_12 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
PYH2_k127_3338367_13 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000002764 246.0
PYH2_k127_3338367_14 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000001471 190.0
PYH2_k127_3338367_15 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000000000000000000000000007458 188.0
PYH2_k127_3338367_16 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000002729 171.0
PYH2_k127_3338367_17 FR47-like protein - - - 0.000000000000000000000000000000000000000000001214 170.0
PYH2_k127_3338367_18 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000008325 166.0
PYH2_k127_3338367_19 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000001803 151.0
PYH2_k127_3338367_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 488.0
PYH2_k127_3338367_21 4Fe-4S binding domain - - - 0.000000000000000000000000000001511 125.0
PYH2_k127_3338367_22 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.0000000000000000000000000003037 119.0
PYH2_k127_3338367_23 response regulator K03413,K07719 - - 0.00000000000000000000002309 104.0
PYH2_k127_3338367_24 Protein of unknown function, DUF255 K06888 - - 0.0000002615 54.0
PYH2_k127_3338367_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000003013 54.0
PYH2_k127_3338367_26 thiamine diphosphate biosynthetic process K03154 - - 0.0007807 45.0
PYH2_k127_3338367_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 476.0
PYH2_k127_3338367_4 epimerase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 470.0
PYH2_k127_3338367_5 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 453.0
PYH2_k127_3338367_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 415.0
PYH2_k127_3338367_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 413.0
PYH2_k127_3338367_8 PFAM Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 403.0
PYH2_k127_3338367_9 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 358.0
PYH2_k127_3362996_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 396.0
PYH2_k127_3362996_1 alcohol dehydrogenase K00086 - 1.1.1.202 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 375.0
PYH2_k127_3362996_2 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 345.0
PYH2_k127_3362996_3 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009541 243.0
PYH2_k127_3362996_4 PFAM Aldo keto reductase family - - - 0.00000001333 56.0
PYH2_k127_3364117_0 elongation factor Tu domain 2 protein K06207 - - 2.364e-292 907.0
PYH2_k127_3364117_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 9.895e-252 789.0
PYH2_k127_3364117_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 481.0
PYH2_k127_3364117_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 384.0
PYH2_k127_3364117_4 FCD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005898 229.0
PYH2_k127_3364117_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000001421 193.0
PYH2_k127_3364117_6 chain release factor K15034 - - 0.00000000000000000000000000000000000000005113 155.0
PYH2_k127_3364117_7 Peptidase dimerisation domain protein K01436 - - 0.0000000000000000003319 89.0
PYH2_k127_3364117_8 serine threonine protein kinase - - - 0.0000000000001309 80.0
PYH2_k127_3378153_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1206.0
PYH2_k127_3378153_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 3.458e-313 970.0
PYH2_k127_3378153_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000001309 154.0
PYH2_k127_3378153_11 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001766 151.0
PYH2_k127_3378153_12 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000007057 147.0
PYH2_k127_3378153_13 MazG-like family - - - 0.00000000000000000000000000003608 121.0
PYH2_k127_3378153_2 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 3.67e-279 885.0
PYH2_k127_3378153_3 Patatin-like phospholipase K06900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 373.0
PYH2_k127_3378153_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 356.0
PYH2_k127_3378153_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 332.0
PYH2_k127_3378153_6 PFAM inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 316.0
PYH2_k127_3378153_7 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000001261 272.0
PYH2_k127_3378153_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006117 245.0
PYH2_k127_3378153_9 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000003254 186.0
PYH2_k127_3381656_0 response regulator, receiver K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002206 258.0
PYH2_k127_3381656_1 Response regulator receiver - - - 0.000000000000000000000003386 107.0
PYH2_k127_3381656_2 Histidine kinase - - - 0.00000000000000000003039 93.0
PYH2_k127_3402567_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000004139 153.0
PYH2_k127_3402567_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000002548 73.0
PYH2_k127_3402567_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000006605 54.0
PYH2_k127_3416969_0 Multicopper oxidase K08100 - 1.3.3.5 4.916e-255 800.0
PYH2_k127_3416969_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 334.0
PYH2_k127_3416969_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000008868 218.0
PYH2_k127_3416969_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000001433 184.0
PYH2_k127_3416969_4 Ion channel - - - 0.0000000000000000000000000000002845 132.0
PYH2_k127_3426854_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 534.0
PYH2_k127_3426854_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 496.0
PYH2_k127_3426854_2 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000129 136.0
PYH2_k127_3426854_3 - - - - 0.000000000000000227 81.0
PYH2_k127_3426854_4 Domain of unknown function (DUF333) K14475 - - 0.000000000000001277 81.0
PYH2_k127_3456675_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000002261 152.0
PYH2_k127_3460167_0 AAA domain - - - 0.00000000000000000000002907 112.0
PYH2_k127_3460167_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000001177 81.0
PYH2_k127_3465664_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000001628 200.0
PYH2_k127_3465664_1 alpha beta - - - 0.000000000000000000000002609 106.0
PYH2_k127_3465664_2 alpha beta - - - 0.000000000000003557 79.0
PYH2_k127_3489728_0 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 458.0
PYH2_k127_3489728_1 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 347.0
PYH2_k127_3489728_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 293.0
PYH2_k127_3489728_3 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
PYH2_k127_3529097_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002666 237.0
PYH2_k127_3529097_1 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000005811 139.0
PYH2_k127_3529097_2 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000002433 132.0
PYH2_k127_3529097_3 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000002594 125.0
PYH2_k127_3530601_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
PYH2_k127_3530601_1 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.0001024 46.0
PYH2_k127_3591842_0 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 357.0
PYH2_k127_3591842_1 Tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 302.0
PYH2_k127_3591842_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000302 154.0
PYH2_k127_3591842_3 T4-like virus tail tube protein gp19 - - - 0.00000000000001009 80.0
PYH2_k127_3622744_0 PFAM aminotransferase, class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 400.0
PYH2_k127_3622744_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 377.0
PYH2_k127_3622744_10 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.000000002131 67.0
PYH2_k127_3622744_2 conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K00484 - 1.5.1.36 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
PYH2_k127_3622744_3 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000009516 226.0
PYH2_k127_3622744_4 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000001775 227.0
PYH2_k127_3622744_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000002635 209.0
PYH2_k127_3622744_6 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000003757 109.0
PYH2_k127_3622744_7 protein conserved in bacteria - - - 0.000000000000007947 74.0
PYH2_k127_3622744_8 Protein of unknown function (DUF4256) - - - 0.00000000000001418 73.0
PYH2_k127_3622744_9 Protein of unknown function (DUF4256) - - - 0.00000000008108 62.0
PYH2_k127_3737694_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 555.0
PYH2_k127_3737694_1 CpXC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 333.0
PYH2_k127_3759104_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 561.0
PYH2_k127_3759104_1 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006421 265.0
PYH2_k127_3759104_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000003865 142.0
PYH2_k127_3764304_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 2.932e-196 622.0
PYH2_k127_3764304_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 587.0
PYH2_k127_3764304_10 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 461.0
PYH2_k127_3764304_11 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 435.0
PYH2_k127_3764304_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 421.0
PYH2_k127_3764304_13 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 417.0
PYH2_k127_3764304_14 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 414.0
PYH2_k127_3764304_15 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 394.0
PYH2_k127_3764304_16 glycerophosphodiester transmembrane transport K02026,K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 374.0
PYH2_k127_3764304_17 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 365.0
PYH2_k127_3764304_18 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 364.0
PYH2_k127_3764304_19 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 361.0
PYH2_k127_3764304_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 578.0
PYH2_k127_3764304_20 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 354.0
PYH2_k127_3764304_21 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 334.0
PYH2_k127_3764304_22 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 299.0
PYH2_k127_3764304_23 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 268.0
PYH2_k127_3764304_24 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000003683 232.0
PYH2_k127_3764304_25 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000005395 167.0
PYH2_k127_3764304_27 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000000000000000000005024 170.0
PYH2_k127_3764304_28 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.0000000000000000000000001182 110.0
PYH2_k127_3764304_29 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000001053 66.0
PYH2_k127_3764304_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 566.0
PYH2_k127_3764304_31 diguanylate cyclase - - - 0.0005502 47.0
PYH2_k127_3764304_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 550.0
PYH2_k127_3764304_5 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 534.0
PYH2_k127_3764304_6 ABC-type sugar transport system periplasmic component K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 533.0
PYH2_k127_3764304_7 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 512.0
PYH2_k127_3764304_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 495.0
PYH2_k127_3764304_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 466.0
PYH2_k127_3769891_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.007e-280 882.0
PYH2_k127_3769891_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.593e-259 824.0
PYH2_k127_3769891_10 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 397.0
PYH2_k127_3769891_11 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 392.0
PYH2_k127_3769891_12 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 382.0
PYH2_k127_3769891_13 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 372.0
PYH2_k127_3769891_14 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 325.0
PYH2_k127_3769891_15 Heat shock protein DnaJ domain protein K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 311.0
PYH2_k127_3769891_16 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 309.0
PYH2_k127_3769891_17 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 298.0
PYH2_k127_3769891_18 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 301.0
PYH2_k127_3769891_19 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 289.0
PYH2_k127_3769891_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.975e-252 793.0
PYH2_k127_3769891_20 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000004297 269.0
PYH2_k127_3769891_21 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004009 274.0
PYH2_k127_3769891_22 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002084 237.0
PYH2_k127_3769891_23 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000008688 209.0
PYH2_k127_3769891_24 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000000000000004731 192.0
PYH2_k127_3769891_25 - - - - 0.0000000000000000000000000000000000000000000000000148 183.0
PYH2_k127_3769891_26 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000001777 183.0
PYH2_k127_3769891_27 PFAM Abortive infection protein - - - 0.00000000000000000000000000000000000000000000000004096 191.0
PYH2_k127_3769891_28 B3 4 domain protein - - - 0.0000000000000000000000000000000000000000000000001121 196.0
PYH2_k127_3769891_29 - - - - 0.0000000000000000000000000000000000000000000000004168 188.0
PYH2_k127_3769891_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 600.0
PYH2_k127_3769891_30 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.00000000000000000000000000000000000000001658 164.0
PYH2_k127_3769891_31 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000135 159.0
PYH2_k127_3769891_32 - - - - 0.00000000000000000000000000000000001434 139.0
PYH2_k127_3769891_33 chromate transporter K07240 - - 0.000000000000000000000000000004063 126.0
PYH2_k127_3769891_34 Protein of unknown function DUF86 - - - 0.000000000000000000000000001303 115.0
PYH2_k127_3769891_35 - - - - 0.000000000000000000000001906 105.0
PYH2_k127_3769891_36 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000006205 98.0
PYH2_k127_3769891_38 Helix-turn-helix domain - - - 0.0000000000004474 75.0
PYH2_k127_3769891_39 - - - - 0.00000000004086 69.0
PYH2_k127_3769891_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 578.0
PYH2_k127_3769891_40 - - - - 0.0000000003016 65.0
PYH2_k127_3769891_41 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000004137 61.0
PYH2_k127_3769891_5 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 567.0
PYH2_k127_3769891_6 aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 496.0
PYH2_k127_3769891_7 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 472.0
PYH2_k127_3769891_8 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 423.0
PYH2_k127_3769891_9 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 422.0
PYH2_k127_3776116_0 Elongator protein 3, MiaB family, Radical SAM - - - 4.206e-268 840.0
PYH2_k127_3776116_1 Inner membrane component of T3SS, cytoplasmic domain - - - 2.476e-205 670.0
PYH2_k127_3776116_10 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000001637 143.0
PYH2_k127_3776116_11 - - - - 0.00000000005507 66.0
PYH2_k127_3776116_12 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000006524 76.0
PYH2_k127_3776116_13 - - - - 0.000000002217 63.0
PYH2_k127_3776116_14 Transcriptional regulator, CarD family K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00002441 53.0
PYH2_k127_3776116_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 428.0
PYH2_k127_3776116_3 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 428.0
PYH2_k127_3776116_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 320.0
PYH2_k127_3776116_5 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002353 289.0
PYH2_k127_3776116_6 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000008807 180.0
PYH2_k127_3776116_7 response to abiotic stimulus - - - 0.00000000000000000000000000000000000002441 149.0
PYH2_k127_3776116_8 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000003793 148.0
PYH2_k127_3776116_9 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000007789 145.0
PYH2_k127_3827527_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 465.0
PYH2_k127_3827527_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 429.0
PYH2_k127_3827527_2 PFAM ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436 365.0
PYH2_k127_3827527_3 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
PYH2_k127_3827527_4 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
PYH2_k127_3827527_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000001971 184.0
PYH2_k127_3827527_6 Putative phosphatase (DUF442) - - - 0.0000000000000000000000000000000000000001089 154.0
PYH2_k127_3827527_7 Kelch repeat-containing protein - - - 0.000002833 58.0
PYH2_k127_3827527_8 BNR repeat-like domain - - - 0.000005773 59.0
PYH2_k127_3892594_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.124e-269 837.0
PYH2_k127_3892594_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 571.0
PYH2_k127_3892594_10 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 351.0
PYH2_k127_3892594_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 341.0
PYH2_k127_3892594_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 332.0
PYH2_k127_3892594_13 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 298.0
PYH2_k127_3892594_14 dolichyl monophosphate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004778 278.0
PYH2_k127_3892594_15 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000855 261.0
PYH2_k127_3892594_16 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008289 255.0
PYH2_k127_3892594_18 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000004253 254.0
PYH2_k127_3892594_19 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000001554 255.0
PYH2_k127_3892594_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 542.0
PYH2_k127_3892594_20 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000000000000000000000000000000000000000472 215.0
PYH2_k127_3892594_21 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003233 201.0
PYH2_k127_3892594_22 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000000000000000000000000005231 205.0
PYH2_k127_3892594_23 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000000000000000000000000000000000032 198.0
PYH2_k127_3892594_24 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000001397 168.0
PYH2_k127_3892594_25 MaoC like domain - - - 0.0000000000000000000000000000000000000000000424 165.0
PYH2_k127_3892594_26 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000003985 153.0
PYH2_k127_3892594_27 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000000008597 156.0
PYH2_k127_3892594_29 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000008107 143.0
PYH2_k127_3892594_30 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000009201 151.0
PYH2_k127_3892594_31 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000006566 138.0
PYH2_k127_3892594_32 Cyclic-di-AMP receptor - - - 0.0000000000000000000000000000000001001 136.0
PYH2_k127_3892594_33 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000004721 120.0
PYH2_k127_3892594_34 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000000001384 112.0
PYH2_k127_3892594_35 response to heat - - - 0.000000000000000000008718 102.0
PYH2_k127_3892594_36 PIN domain - - - 0.0000000000000000000103 96.0
PYH2_k127_3892594_37 Cyclic-di-AMP receptor - - - 0.00000000000003804 77.0
PYH2_k127_3892594_38 Bacterial extracellular solute-binding protein K11069 - - 0.00000000677 62.0
PYH2_k127_3892594_39 PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000001708 66.0
PYH2_k127_3892594_4 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 445.0
PYH2_k127_3892594_40 toxin-antitoxin pair type II binding - - - 0.00004649 48.0
PYH2_k127_3892594_42 - - - - 0.00006954 55.0
PYH2_k127_3892594_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 439.0
PYH2_k127_3892594_6 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 400.0
PYH2_k127_3892594_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 391.0
PYH2_k127_3892594_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 364.0
PYH2_k127_3892594_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 368.0
PYH2_k127_3919601_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.564e-262 818.0
PYH2_k127_3919601_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 492.0
PYH2_k127_3919601_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 333.0
PYH2_k127_3919601_3 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000007006 200.0
PYH2_k127_3919601_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000004725 120.0
PYH2_k127_3919601_5 YCII-related domain - - - 0.0000000000000001035 85.0
PYH2_k127_3919601_6 - - - - 0.00000000000496 74.0
PYH2_k127_3961467_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000002781 156.0
PYH2_k127_3961467_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000007288 150.0
PYH2_k127_3961467_2 - - - - 0.000000000000000000000000000000005571 138.0
PYH2_k127_3961467_3 - - - - 0.0001221 50.0
PYH2_k127_4041849_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 434.0
PYH2_k127_4041849_1 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 407.0
PYH2_k127_4041849_10 - - - - 0.000000000004454 76.0
PYH2_k127_4041849_11 Dienelactone hydrolase - - - 0.0000000001505 72.0
PYH2_k127_4041849_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 413.0
PYH2_k127_4041849_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 400.0
PYH2_k127_4041849_4 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 347.0
PYH2_k127_4041849_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
PYH2_k127_4041849_6 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000001603 200.0
PYH2_k127_4041849_7 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000001023 144.0
PYH2_k127_4041849_8 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000003025 124.0
PYH2_k127_4041849_9 Flavodoxin domain - - - 0.000000000000002381 84.0
PYH2_k127_4066647_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.544e-312 966.0
PYH2_k127_4066647_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 1.033e-228 721.0
PYH2_k127_4066647_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 336.0
PYH2_k127_4066647_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000233 118.0
PYH2_k127_408626_0 Short-chain dehydrogenase reductase SDR - - - 8.14e-250 788.0
PYH2_k127_408626_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.411e-216 694.0
PYH2_k127_408626_10 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 496.0
PYH2_k127_408626_11 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 454.0
PYH2_k127_408626_12 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 467.0
PYH2_k127_408626_13 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 443.0
PYH2_k127_408626_14 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 436.0
PYH2_k127_408626_15 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 421.0
PYH2_k127_408626_16 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 419.0
PYH2_k127_408626_17 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 412.0
PYH2_k127_408626_18 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 407.0
PYH2_k127_408626_19 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 364.0
PYH2_k127_408626_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 591.0
PYH2_k127_408626_20 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 355.0
PYH2_k127_408626_21 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 347.0
PYH2_k127_408626_22 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
PYH2_k127_408626_23 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
PYH2_k127_408626_24 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 333.0
PYH2_k127_408626_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 333.0
PYH2_k127_408626_26 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 311.0
PYH2_k127_408626_27 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 313.0
PYH2_k127_408626_28 NAD-dependent epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
PYH2_k127_408626_29 ADP-glyceromanno-heptose 6-epimerase activity K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 288.0
PYH2_k127_408626_3 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 534.0
PYH2_k127_408626_30 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
PYH2_k127_408626_31 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000001663 226.0
PYH2_k127_408626_32 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000004054 226.0
PYH2_k127_408626_33 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000002531 216.0
PYH2_k127_408626_34 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000452 206.0
PYH2_k127_408626_35 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000005738 202.0
PYH2_k127_408626_36 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000000001334 193.0
PYH2_k127_408626_37 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000002513 171.0
PYH2_k127_408626_38 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000007039 157.0
PYH2_k127_408626_39 Nitroreductase family - - - 0.000000000000000000000000000000000000002 155.0
PYH2_k127_408626_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 520.0
PYH2_k127_408626_42 TIGRFAM transposase, IS605 OrfB family, central region - - - 0.0000000000000000000174 93.0
PYH2_k127_408626_43 - - - - 0.000000000000000005651 87.0
PYH2_k127_408626_44 helix_turn_helix, mercury resistance - - - 0.000000000000000115 82.0
PYH2_k127_408626_47 - - - - 0.0000000002221 66.0
PYH2_k127_408626_49 - - - - 0.0000004548 53.0
PYH2_k127_408626_5 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 531.0
PYH2_k127_408626_50 Probable transposase - - - 0.00001303 50.0
PYH2_k127_408626_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 512.0
PYH2_k127_408626_7 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 489.0
PYH2_k127_408626_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 479.0
PYH2_k127_408626_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 463.0
PYH2_k127_4173_0 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 361.0
PYH2_k127_4173_1 Transketolase, central region K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 307.0
PYH2_k127_4173_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 271.0
PYH2_k127_4173_3 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 0.00000000000000000000000000000009819 126.0
PYH2_k127_4173_4 Asp/Glu/Hydantoin racemase - - - 0.000000000000000000000000000007452 130.0
PYH2_k127_4173_5 PFAM Isochorismatase - - - 0.000000000003169 76.0
PYH2_k127_4197607_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1117.0
PYH2_k127_4197607_1 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 462.0
PYH2_k127_4197607_10 amidohydrolase - - - 0.0000000000000001655 79.0
PYH2_k127_4197607_11 amidohydrolase - - - 0.00000000000002145 76.0
PYH2_k127_4197607_12 amidohydrolase - - - 0.00000000002602 65.0
PYH2_k127_4197607_13 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000008338 58.0
PYH2_k127_4197607_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 338.0
PYH2_k127_4197607_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 287.0
PYH2_k127_4197607_4 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000006319 216.0
PYH2_k127_4197607_5 transmembrane transporter activity K05820 - - 0.0000000000000000000000000000000000000000000000000000003201 208.0
PYH2_k127_4197607_6 Domain of unknown function (DUF4037) - - - 0.0000000000000000000000000000000000000000000000000006314 187.0
PYH2_k127_4197607_7 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000006017 167.0
PYH2_k127_4197607_8 peroxiredoxin activity - - - 0.00000000000000000000000002494 115.0
PYH2_k127_4197607_9 amidohydrolase - - - 0.0000000000000000002669 90.0
PYH2_k127_4210049_0 succinyl-diaminopimelate desuccinylase activity K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0 1201.0
PYH2_k127_4210049_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1124.0
PYH2_k127_4210049_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002799 270.0
PYH2_k127_4210049_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000001785 210.0
PYH2_k127_4210049_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000001499 192.0
PYH2_k127_4210049_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000001092 191.0
PYH2_k127_4210049_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000001143 177.0
PYH2_k127_4210049_16 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.0000000000000000000000000000000000007648 142.0
PYH2_k127_4210049_17 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000003547 137.0
PYH2_k127_4210049_18 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000005086 131.0
PYH2_k127_4210049_19 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000002218 98.0
PYH2_k127_4210049_2 Stage II sporulation E family protein - - - 2.059e-216 716.0
PYH2_k127_4210049_20 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000008178 109.0
PYH2_k127_4210049_22 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000001949 75.0
PYH2_k127_4210049_23 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000001045 68.0
PYH2_k127_4210049_24 TIGRFAM DNA protecting protein DprA K04096 - - 0.00005496 50.0
PYH2_k127_4210049_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 3.005e-203 640.0
PYH2_k127_4210049_4 Aminotransferase K00812 - 2.6.1.1 7.722e-203 639.0
PYH2_k127_4210049_5 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 565.0
PYH2_k127_4210049_7 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 537.0
PYH2_k127_4210049_8 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 501.0
PYH2_k127_4210049_9 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 359.0
PYH2_k127_4276255_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 516.0
PYH2_k127_4276255_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 297.0
PYH2_k127_4340707_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 319.0
PYH2_k127_4340707_1 PFAM Beta-lactamase K18988 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 304.0
PYH2_k127_4340707_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000008929 217.0
PYH2_k127_4340707_3 Protein of unknown function (DUF3887) K06889 - - 0.000002082 56.0
PYH2_k127_4340707_4 - - - - 0.000002746 59.0
PYH2_k127_4368782_0 Belongs to the RtcB family K14415 - 6.5.1.3 9.024e-238 743.0
PYH2_k127_4368782_1 DHH family K07462 - - 1.26e-201 652.0
PYH2_k127_4368782_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 496.0
PYH2_k127_4368782_3 PFAM ABC transporter related K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
PYH2_k127_4368782_4 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000005994 177.0
PYH2_k127_4368782_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000009626 135.0
PYH2_k127_4368782_6 PD-(D/E)XK nuclease superfamily - - - 0.000000009164 60.0
PYH2_k127_4388949_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 489.0
PYH2_k127_4388949_1 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 371.0
PYH2_k127_4388949_10 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000002966 111.0
PYH2_k127_4388949_11 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000009104 69.0
PYH2_k127_4388949_12 Winged helix DNA-binding domain K09927 - - 0.0000002198 55.0
PYH2_k127_4388949_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 320.0
PYH2_k127_4388949_3 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
PYH2_k127_4388949_4 heat shock protein 70 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 317.0
PYH2_k127_4388949_5 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002625 260.0
PYH2_k127_4388949_6 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
PYH2_k127_4388949_7 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000003945 186.0
PYH2_k127_4388949_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000005105 163.0
PYH2_k127_4388949_9 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000003827 132.0
PYH2_k127_4389084_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.634e-310 954.0
PYH2_k127_4389084_1 PFAM ABC transporter K06020 - 3.6.3.25 2.049e-267 832.0
PYH2_k127_4389084_10 Helix-turn-helix type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000372 266.0
PYH2_k127_4389084_11 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001599 253.0
PYH2_k127_4389084_12 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000000000000011 206.0
PYH2_k127_4389084_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002456 218.0
PYH2_k127_4389084_14 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000009081 206.0
PYH2_k127_4389084_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000008662 190.0
PYH2_k127_4389084_16 - - - - 0.0000000000000000000000000000000000000000000000009383 178.0
PYH2_k127_4389084_17 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000348 159.0
PYH2_k127_4389084_18 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.000000000000000000000000000000000000004576 154.0
PYH2_k127_4389084_19 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.00000000000000000000000000000000123 135.0
PYH2_k127_4389084_2 PFAM amidohydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 543.0
PYH2_k127_4389084_20 - - - - 0.000000000000000000000000000000002662 137.0
PYH2_k127_4389084_21 PFAM helix-turn-helix- domain containing protein, AraC type K13653 - - 0.0000000000000000000000000008772 124.0
PYH2_k127_4389084_22 Large exoproteins involved in heme utilization or adhesion - - - 0.0000000119 68.0
PYH2_k127_4389084_3 fad dependent oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 485.0
PYH2_k127_4389084_4 Peptidase dimerisation domain K21613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 476.0
PYH2_k127_4389084_5 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 398.0
PYH2_k127_4389084_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 391.0
PYH2_k127_4389084_7 Response regulator, receiver K02487,K03407,K03413,K06596,K11526,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001113 282.0
PYH2_k127_4389084_8 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001141 271.0
PYH2_k127_4389084_9 Aldo/keto reductase family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009097 268.0
PYH2_k127_4392855_0 peptidase M29 aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 430.0
PYH2_k127_4392855_1 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000624 84.0
PYH2_k127_4392855_2 PFAM Transposase DDE domain - - - 0.000000000007962 67.0
PYH2_k127_4414313_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 409.0
PYH2_k127_4414313_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 385.0
PYH2_k127_4414313_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 358.0
PYH2_k127_4414313_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000001451 72.0
PYH2_k127_4447064_0 Cysteine rich repeat - - - 0.00000000000000000000000000000000000000001814 156.0
PYH2_k127_4447064_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000005179 130.0
PYH2_k127_4447064_2 antisigma factor binding K02066,K04749 - - 0.0000000000000000000000143 104.0
PYH2_k127_4447064_3 Universal stress protein family - - - 0.000000007705 61.0
PYH2_k127_4470763_0 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 344.0
PYH2_k127_4470763_1 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000003385 172.0
PYH2_k127_4566299_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1502.0
PYH2_k127_4566299_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1174.0
PYH2_k127_4566299_10 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 375.0
PYH2_k127_4566299_11 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 343.0
PYH2_k127_4566299_12 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 345.0
PYH2_k127_4566299_13 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 326.0
PYH2_k127_4566299_14 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 311.0
PYH2_k127_4566299_15 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007871 283.0
PYH2_k127_4566299_16 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 267.0
PYH2_k127_4566299_17 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002106 261.0
PYH2_k127_4566299_18 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000644 239.0
PYH2_k127_4566299_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006151 229.0
PYH2_k127_4566299_2 May be involved in recombinational repair of damaged DNA K03631 - - 9.581e-213 675.0
PYH2_k127_4566299_20 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000009271 192.0
PYH2_k127_4566299_21 3-demethylubiquinone-9 3-O-methyltransferase activity K15257,K16868,K18827,K20444 - 2.1.1.265,2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000005751 179.0
PYH2_k127_4566299_22 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000000000000000104 170.0
PYH2_k127_4566299_23 - - - - 0.00000000000000000000000000000000000000000001745 170.0
PYH2_k127_4566299_24 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000009552 156.0
PYH2_k127_4566299_25 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000002557 165.0
PYH2_k127_4566299_26 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000001742 148.0
PYH2_k127_4566299_27 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000012 138.0
PYH2_k127_4566299_28 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000001243 138.0
PYH2_k127_4566299_29 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000003943 134.0
PYH2_k127_4566299_3 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 535.0
PYH2_k127_4566299_30 PFAM regulatory protein, MerR - - - 0.000000000000000000000000001176 120.0
PYH2_k127_4566299_31 CAAX protease self-immunity K07052 - - 0.00000000000000000000000009864 118.0
PYH2_k127_4566299_32 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000009297 109.0
PYH2_k127_4566299_33 -O-antigen - - - 0.00000000000000000002362 105.0
PYH2_k127_4566299_34 PFAM Forkhead-associated protein - - - 0.000000000000001844 83.0
PYH2_k127_4566299_36 PFAM Forkhead-associated protein - - - 0.00000000006714 64.0
PYH2_k127_4566299_4 aminopeptidase activity K01179,K01269 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 485.0
PYH2_k127_4566299_5 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 458.0
PYH2_k127_4566299_6 PFAM PUCC protein K08226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 423.0
PYH2_k127_4566299_7 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 403.0
PYH2_k127_4566299_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 391.0
PYH2_k127_4566299_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 378.0
PYH2_k127_4589060_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 9.189e-291 911.0
PYH2_k127_4589060_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.791e-237 739.0
PYH2_k127_4589060_10 Phosphotransferase enzyme family K18844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 351.0
PYH2_k127_4589060_11 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 321.0
PYH2_k127_4589060_12 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 281.0
PYH2_k127_4589060_13 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001252 275.0
PYH2_k127_4589060_14 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005061 264.0
PYH2_k127_4589060_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003271 247.0
PYH2_k127_4589060_16 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000001165 224.0
PYH2_k127_4589060_17 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000000000000000000000000004528 208.0
PYH2_k127_4589060_18 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000001711 200.0
PYH2_k127_4589060_19 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000003511 187.0
PYH2_k127_4589060_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 589.0
PYH2_k127_4589060_20 PFAM Abortive infection protein - - - 0.00000000000000000000000000000000000000000000000001536 192.0
PYH2_k127_4589060_21 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000001239 186.0
PYH2_k127_4589060_22 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000005073 169.0
PYH2_k127_4589060_23 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000799 163.0
PYH2_k127_4589060_24 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000004087 157.0
PYH2_k127_4589060_25 PFAM regulatory protein GntR HTH K07979 - - 0.000000000000000000000000000000000000006027 149.0
PYH2_k127_4589060_26 - - - - 0.00000000000000000000000000000000000001247 149.0
PYH2_k127_4589060_28 - - - - 0.0000000000000000000000001796 115.0
PYH2_k127_4589060_29 - - - - 0.0000000000000001396 90.0
PYH2_k127_4589060_3 Oligopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 523.0
PYH2_k127_4589060_31 methyltransferase activity - - - 0.0000000000000004263 85.0
PYH2_k127_4589060_32 FecR protein - - - 0.00000001352 66.0
PYH2_k127_4589060_33 Protein of unknown function (DUF664) - - - 0.000001098 57.0
PYH2_k127_4589060_34 spore germination - - - 0.00006735 46.0
PYH2_k127_4589060_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 452.0
PYH2_k127_4589060_5 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 440.0
PYH2_k127_4589060_6 PFAM isocitrate isopropylmalate dehydrogenase K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 443.0
PYH2_k127_4589060_7 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 398.0
PYH2_k127_4589060_8 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 406.0
PYH2_k127_4589060_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 386.0
PYH2_k127_4633243_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 2.808e-266 831.0
PYH2_k127_4633243_1 cobalamin binding - - - 4.231e-249 780.0
PYH2_k127_4633243_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 334.0
PYH2_k127_4633243_11 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000001392 233.0
PYH2_k127_4633243_12 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000652 211.0
PYH2_k127_4633243_13 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000008523 197.0
PYH2_k127_4633243_14 CYTH domain - - - 0.000000000000000000000000000000000000000000000000000008425 194.0
PYH2_k127_4633243_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000001563 189.0
PYH2_k127_4633243_16 Contains PIN domain - - - 0.0000000000000000000000000000000000000000000000000002424 189.0
PYH2_k127_4633243_17 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000001202 190.0
PYH2_k127_4633243_18 - - - - 0.000000000000000000000000000000000000000007358 157.0
PYH2_k127_4633243_19 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001441 154.0
PYH2_k127_4633243_2 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 590.0
PYH2_k127_4633243_21 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000003873 134.0
PYH2_k127_4633243_22 phosphorelay signal transduction system - - - 0.0000000000000000000000000000002555 130.0
PYH2_k127_4633243_23 Sodium hydrogen exchanger - - - 0.00000000000000000000000000002587 119.0
PYH2_k127_4633243_24 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000001577 111.0
PYH2_k127_4633243_25 LysM domain - - - 0.00000000000000000000775 101.0
PYH2_k127_4633243_26 Uncharacterised protein family (UPF0175) - - - 0.000000000001322 74.0
PYH2_k127_4633243_27 - - - - 0.000000000002469 80.0
PYH2_k127_4633243_28 PFAM glycoside hydrolase family 10 - - - 0.0000000001684 74.0
PYH2_k127_4633243_29 Tetratricopeptide repeat - - - 0.0000000004901 72.0
PYH2_k127_4633243_3 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 569.0
PYH2_k127_4633243_30 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000006089 68.0
PYH2_k127_4633243_4 modification enzyme, MiaB family K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 492.0
PYH2_k127_4633243_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 467.0
PYH2_k127_4633243_6 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 412.0
PYH2_k127_4633243_7 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 373.0
PYH2_k127_4633243_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 370.0
PYH2_k127_4633243_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 352.0
PYH2_k127_4648976_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 - 3.2.1.177,3.2.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 474.0
PYH2_k127_4648976_1 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 377.0
PYH2_k127_4648976_10 acetyltransferase - - - 0.00000000000000000000000000003043 127.0
PYH2_k127_4648976_11 Major facilitator Superfamily - - - 0.000000000000000000000000001706 127.0
PYH2_k127_4648976_12 Acetyltransferase, GNAT family - - - 0.00000000000000001962 90.0
PYH2_k127_4648976_13 ECF sigma factor K03088 - - 0.00000000001491 72.0
PYH2_k127_4648976_14 phosphinothricin N-acetyltransferase activity - - - 0.00000009246 55.0
PYH2_k127_4648976_15 ArsR family transcriptional regulator - - - 0.000000257 62.0
PYH2_k127_4648976_16 serine-type peptidase activity K08676 - - 0.000007003 58.0
PYH2_k127_4648976_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
PYH2_k127_4648976_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001042 246.0
PYH2_k127_4648976_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008985 239.0
PYH2_k127_4648976_5 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000008779 212.0
PYH2_k127_4648976_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000002505 201.0
PYH2_k127_4648976_7 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000000000000000000000000000005828 166.0
PYH2_k127_4648976_8 - - - - 0.0000000000000000000000000000000000579 137.0
PYH2_k127_4648976_9 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000002309 124.0
PYH2_k127_4673763_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 407.0
PYH2_k127_4673763_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001444 166.0
PYH2_k127_4676457_0 Alkyl sulfatase dimerisation K01138 - - 0.00000000000000000000000000001454 135.0
PYH2_k127_4697934_0 Amidohydrolase family - - - 6.225e-218 684.0
PYH2_k127_4697934_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 567.0
PYH2_k127_4697934_10 WD40-like Beta Propeller Repeat - - - 0.00000007157 65.0
PYH2_k127_4697934_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
PYH2_k127_4697934_3 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000007699 260.0
PYH2_k127_4697934_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000001402 248.0
PYH2_k127_4697934_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000798 199.0
PYH2_k127_4697934_6 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000382 188.0
PYH2_k127_4697934_7 RNHCP domain - - - 0.000000000000000000005786 99.0
PYH2_k127_4697934_8 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000001098 82.0
PYH2_k127_4697934_9 AAA domain - - - 0.00000000000741 74.0
PYH2_k127_4710685_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.237e-237 755.0
PYH2_k127_4710685_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 362.0
PYH2_k127_4710685_3 Sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 305.0
PYH2_k127_4710685_5 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000001007 117.0
PYH2_k127_4710685_6 Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.0000000000000000007023 90.0
PYH2_k127_4817722_0 the aldose L-fucose into the corresponding ketose L-fuculose K01818 - 5.3.1.25,5.3.1.3 2.087e-296 918.0
PYH2_k127_4817722_1 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 2.163e-276 857.0
PYH2_k127_4817722_10 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 429.0
PYH2_k127_4817722_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 421.0
PYH2_k127_4817722_12 alcohol dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 383.0
PYH2_k127_4817722_13 Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 327.0
PYH2_k127_4817722_14 Class ii aldolase K01628,K01629 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008994,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.17,4.1.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 326.0
PYH2_k127_4817722_15 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 327.0
PYH2_k127_4817722_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 330.0
PYH2_k127_4817722_17 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 322.0
PYH2_k127_4817722_18 Membrane component of a K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 329.0
PYH2_k127_4817722_19 ABC-type sugar transport system, periplasmic component K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003677 272.0
PYH2_k127_4817722_2 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 8.525e-270 850.0
PYH2_k127_4817722_20 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001318 269.0
PYH2_k127_4817722_21 Class ii aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000007653 210.0
PYH2_k127_4817722_22 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000009015 185.0
PYH2_k127_4817722_23 fucose binding K02431 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016853,GO:0016854,GO:0016857,GO:0030246,GO:0036094,GO:0042806,GO:0044424,GO:0044464,GO:0048029 5.1.3.29 0.0000000000000000000000000000000000000001153 154.0
PYH2_k127_4817722_24 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000004908 107.0
PYH2_k127_4817722_26 polysaccharide deacetylase - - - 0.0000005435 59.0
PYH2_k127_4817722_3 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 1.274e-268 834.0
PYH2_k127_4817722_4 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 5.986e-194 621.0
PYH2_k127_4817722_5 Belongs to the rhamnose isomerase family K01813 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 602.0
PYH2_k127_4817722_6 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 577.0
PYH2_k127_4817722_7 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 582.0
PYH2_k127_4817722_8 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 557.0
PYH2_k127_4817722_9 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 537.0
PYH2_k127_482051_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 1.352e-221 696.0
PYH2_k127_482051_1 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 2.796e-214 669.0
PYH2_k127_482051_10 Fibronectin type III-like domain - - - 0.000000000000000000000000000000002686 131.0
PYH2_k127_482051_11 Transglutaminase-like superfamily - - - 0.0000000000000000007349 98.0
PYH2_k127_482051_12 Domain of unknown function (DUF4404) - - - 0.0003061 48.0
PYH2_k127_482051_2 DNA polymerase K02337,K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 610.0
PYH2_k127_482051_3 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 414.0
PYH2_k127_482051_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 391.0
PYH2_k127_482051_5 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 353.0
PYH2_k127_482051_6 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 331.0
PYH2_k127_482051_7 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 333.0
PYH2_k127_482051_8 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
PYH2_k127_482051_9 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 0.0000000000000000000000000000000000001665 141.0
PYH2_k127_4830545_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 527.0
PYH2_k127_4830545_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 518.0
PYH2_k127_4830545_10 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000002945 209.0
PYH2_k127_4830545_11 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000003741 108.0
PYH2_k127_4830545_12 cell redox homeostasis - - - 0.000000000000000001028 100.0
PYH2_k127_4830545_13 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000003517 76.0
PYH2_k127_4830545_14 Antibiotic biosynthesis monooxygenase - - - 0.000000000002318 72.0
PYH2_k127_4830545_15 Belongs to the 'phage' integrase family K04763 - - 0.00000000005356 66.0
PYH2_k127_4830545_16 - - - - 0.00000006332 62.0
PYH2_k127_4830545_17 Phage integrase family - - - 0.000001224 58.0
PYH2_k127_4830545_18 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0001392 51.0
PYH2_k127_4830545_19 Polyketide cyclase / dehydrase and lipid transport - - - 0.0001823 50.0
PYH2_k127_4830545_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 462.0
PYH2_k127_4830545_3 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 391.0
PYH2_k127_4830545_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 321.0
PYH2_k127_4830545_5 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 305.0
PYH2_k127_4830545_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005013 284.0
PYH2_k127_4830545_7 PFAM Vitamin K epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002676 260.0
PYH2_k127_4830545_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001863 259.0
PYH2_k127_4830545_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000009336 229.0
PYH2_k127_4842489_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1090.0
PYH2_k127_4842489_1 elongation factor Tu domain 2 protein K02355 - - 1.169e-309 962.0
PYH2_k127_4842489_10 Biogenesis protein K02275,K09792,K17686 - 1.9.3.1,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 386.0
PYH2_k127_4842489_11 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 379.0
PYH2_k127_4842489_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 374.0
PYH2_k127_4842489_13 PFAM type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 369.0
PYH2_k127_4842489_14 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
PYH2_k127_4842489_16 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 344.0
PYH2_k127_4842489_17 Lipid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 336.0
PYH2_k127_4842489_18 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 329.0
PYH2_k127_4842489_19 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 331.0
PYH2_k127_4842489_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.673e-234 736.0
PYH2_k127_4842489_20 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 321.0
PYH2_k127_4842489_21 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 318.0
PYH2_k127_4842489_22 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 310.0
PYH2_k127_4842489_23 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
PYH2_k127_4842489_24 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005436 267.0
PYH2_k127_4842489_25 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
PYH2_k127_4842489_26 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000001916 249.0
PYH2_k127_4842489_28 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000004618 221.0
PYH2_k127_4842489_29 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000001942 205.0
PYH2_k127_4842489_3 PFAM type II secretion system protein E K02283 - - 2.326e-232 726.0
PYH2_k127_4842489_30 - - - - 0.000000000000000000000000000000000000000000000000000000007678 202.0
PYH2_k127_4842489_31 - - - - 0.00000000000000000000000000000000000000000000000001791 188.0
PYH2_k127_4842489_32 methyltransferase activity K00569 - 2.1.1.67 0.00000000000000000000000000000000000000001206 160.0
PYH2_k127_4842489_33 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000001129 157.0
PYH2_k127_4842489_34 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000001501 141.0
PYH2_k127_4842489_35 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000000003873 134.0
PYH2_k127_4842489_36 - - - - 0.0000000000000000000000000000001573 126.0
PYH2_k127_4842489_37 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.0000000000000000000000000001944 121.0
PYH2_k127_4842489_38 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000002937 87.0
PYH2_k127_4842489_39 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.0000000000000000168 86.0
PYH2_k127_4842489_4 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 7.638e-205 642.0
PYH2_k127_4842489_40 PFAM DnaJ homologue, subfamily C, member 28, conserved domain - - - 0.00000000000000522 78.0
PYH2_k127_4842489_41 protein conserved in bacteria - - - 0.0000000000001088 74.0
PYH2_k127_4842489_42 ThiS family K03636 - - 0.00000000000134 71.0
PYH2_k127_4842489_44 Thioredoxin K03671 - - 0.000001952 52.0
PYH2_k127_4842489_45 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0001185 49.0
PYH2_k127_4842489_5 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 484.0
PYH2_k127_4842489_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 477.0
PYH2_k127_4842489_7 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 464.0
PYH2_k127_4842489_8 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 446.0
PYH2_k127_4842489_9 NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
PYH2_k127_4902026_0 transcription factor binding K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 422.0
PYH2_k127_4907259_0 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001264 275.0
PYH2_k127_4907259_1 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001924 253.0
PYH2_k127_4907259_2 GYD domain - - - 0.000000000000000000000000000001137 123.0
PYH2_k127_4907259_3 Wd40 repeat-containing protein K12132 - 2.7.11.1 0.000000000000001468 89.0
PYH2_k127_4907259_4 Transposase IS200 like - - - 0.00000000000001774 74.0
PYH2_k127_4907259_5 ADP binding - - - 0.000000003471 62.0
PYH2_k127_4943191_0 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 345.0
PYH2_k127_4943191_1 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000003636 188.0
PYH2_k127_4943191_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000007332 173.0
PYH2_k127_4943191_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.00002741 48.0
PYH2_k127_4953629_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 472.0
PYH2_k127_4953629_1 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 353.0
PYH2_k127_4953629_2 Peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
PYH2_k127_4953629_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004239 218.0
PYH2_k127_4953629_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000002069 179.0
PYH2_k127_4953629_5 - - - - 0.000000000000000000000001731 108.0
PYH2_k127_4962047_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1596.0
PYH2_k127_4962047_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 1.768e-310 976.0
PYH2_k127_4962047_10 pathogenesis K21471,K21687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 522.0
PYH2_k127_4962047_11 SMART AAA ATPase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 490.0
PYH2_k127_4962047_12 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 413.0
PYH2_k127_4962047_13 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 389.0
PYH2_k127_4962047_14 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 382.0
PYH2_k127_4962047_15 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 383.0
PYH2_k127_4962047_16 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 356.0
PYH2_k127_4962047_17 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 298.0
PYH2_k127_4962047_18 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
PYH2_k127_4962047_19 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 295.0
PYH2_k127_4962047_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.376e-297 931.0
PYH2_k127_4962047_20 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 293.0
PYH2_k127_4962047_21 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 270.0
PYH2_k127_4962047_22 amino acid-binding ACT domain protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
PYH2_k127_4962047_23 succinylglutamate desuccinylase aspartoacylase K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000004479 240.0
PYH2_k127_4962047_24 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000009286 234.0
PYH2_k127_4962047_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000009772 220.0
PYH2_k127_4962047_26 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000008518 220.0
PYH2_k127_4962047_27 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000002492 214.0
PYH2_k127_4962047_28 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000001115 207.0
PYH2_k127_4962047_29 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
PYH2_k127_4962047_3 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 1.419e-229 732.0
PYH2_k127_4962047_30 phosphatidylcholine synthase K01004 - 2.7.8.24 0.00000000000000000000000000000000000000000000000001361 188.0
PYH2_k127_4962047_31 Acyl-transferase K00655,K00945 - 2.3.1.51,2.7.4.25 0.00000000000000000000000000000000000000000000000001538 187.0
PYH2_k127_4962047_32 - - - - 0.0000000000000000000000000000000000000000000000003762 181.0
PYH2_k127_4962047_33 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000003623 178.0
PYH2_k127_4962047_34 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000002184 169.0
PYH2_k127_4962047_35 GtrA-like protein - - - 0.0000000000000000000000000000000000000000001755 164.0
PYH2_k127_4962047_36 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000004181 162.0
PYH2_k127_4962047_37 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000003898 154.0
PYH2_k127_4962047_38 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000006344 137.0
PYH2_k127_4962047_39 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000004924 129.0
PYH2_k127_4962047_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.254e-217 684.0
PYH2_k127_4962047_41 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000001128 86.0
PYH2_k127_4962047_5 PFAM peptidase M20 - - - 5.604e-217 681.0
PYH2_k127_4962047_6 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 578.0
PYH2_k127_4962047_7 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 544.0
PYH2_k127_4962047_8 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 540.0
PYH2_k127_4962047_9 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 533.0
PYH2_k127_4969177_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 346.0
PYH2_k127_4969177_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 339.0
PYH2_k127_4969177_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000897 251.0
PYH2_k127_4969177_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
PYH2_k127_4969177_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000929 197.0
PYH2_k127_4969177_5 - K01992 - - 0.000000000000002796 84.0
PYH2_k127_4969177_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000001675 63.0
PYH2_k127_506332_0 ABC transporter transmembrane region K06147 - - 5.501e-243 765.0
PYH2_k127_506332_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 603.0
PYH2_k127_506332_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 453.0
PYH2_k127_506332_3 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 341.0
PYH2_k127_506332_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 328.0
PYH2_k127_506332_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 299.0
PYH2_k127_506332_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006456 280.0
PYH2_k127_506332_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002943 274.0
PYH2_k127_506332_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001027 256.0
PYH2_k127_506332_9 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007816 263.0
PYH2_k127_5070102_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 479.0
PYH2_k127_5070102_1 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
PYH2_k127_5070102_2 Nacht domain K13730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 282.0
PYH2_k127_5070102_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000009197 261.0
PYH2_k127_5070102_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000003047 182.0
PYH2_k127_5070102_5 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000003591 143.0
PYH2_k127_5070102_6 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000002231 124.0
PYH2_k127_5140558_0 ammonia-lyase activity K01745 - 4.3.1.3 4.354e-251 782.0
PYH2_k127_5140558_1 ATPases associated with a variety of cellular activities K02056,K06400 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 508.0
PYH2_k127_5140558_10 Parallel beta-helix repeats - - - 0.000000000005989 80.0
PYH2_k127_5140558_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 480.0
PYH2_k127_5140558_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 467.0
PYH2_k127_5140558_4 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 461.0
PYH2_k127_5140558_5 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 327.0
PYH2_k127_5140558_6 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002287 288.0
PYH2_k127_5140558_7 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001645 286.0
PYH2_k127_5140558_8 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
PYH2_k127_5140558_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000001195 149.0
PYH2_k127_522414_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 613.0
PYH2_k127_522414_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 583.0
PYH2_k127_522414_10 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000001111 196.0
PYH2_k127_522414_11 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000006679 201.0
PYH2_k127_522414_12 Histidine kinase - - - 0.000000000000000000000000000000000000000001599 174.0
PYH2_k127_522414_13 Response regulator, receiver K11443 - - 0.0000000000000000000000000000000007321 136.0
PYH2_k127_522414_14 - - - - 0.0000000000000000000000000001203 128.0
PYH2_k127_522414_15 Cytochrome b subunit of the bc complex K00412 - - 0.0000000000000000000000000002705 132.0
PYH2_k127_522414_16 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000001087 115.0
PYH2_k127_522414_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000002941 96.0
PYH2_k127_522414_18 Cytochrome c554 and c-prime - - - 0.0000000000001372 82.0
PYH2_k127_522414_19 Transcriptional regulator, MerR family - - - 0.00006767 49.0
PYH2_k127_522414_2 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 378.0
PYH2_k127_522414_20 YtxH-like protein - - - 0.0002039 47.0
PYH2_k127_522414_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 375.0
PYH2_k127_522414_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 360.0
PYH2_k127_522414_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 359.0
PYH2_k127_522414_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 334.0
PYH2_k127_522414_7 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
PYH2_k127_522414_8 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
PYH2_k127_522414_9 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000001718 215.0
PYH2_k127_5226405_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0 1362.0
PYH2_k127_5226405_1 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 553.0
PYH2_k127_5226405_2 Alpha-amylase domain K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 368.0
PYH2_k127_5226405_3 PFAM Binding-protein-dependent transport system inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 355.0
PYH2_k127_5226405_4 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002503 245.0
PYH2_k127_5253760_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.59e-231 720.0
PYH2_k127_5253760_1 Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 595.0
PYH2_k127_5253760_10 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001109 303.0
PYH2_k127_5253760_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004268 274.0
PYH2_k127_5253760_12 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002911 253.0
PYH2_k127_5253760_13 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000001036 233.0
PYH2_k127_5253760_14 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
PYH2_k127_5253760_15 PFAM response regulator receiveR - - - 0.000000000000000000000000000000000000000000000000000000000006505 210.0
PYH2_k127_5253760_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000002864 211.0
PYH2_k127_5253760_17 - - - - 0.0000000000000000000000000000000000000000000000000005822 194.0
PYH2_k127_5253760_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000002396 137.0
PYH2_k127_5253760_19 - - - - 0.000000000000000000000000000000006827 143.0
PYH2_k127_5253760_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 436.0
PYH2_k127_5253760_20 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000008998 129.0
PYH2_k127_5253760_21 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000001092 120.0
PYH2_k127_5253760_22 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000001237 131.0
PYH2_k127_5253760_23 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000001657 84.0
PYH2_k127_5253760_25 YGGT family K02221 - - 0.000000008589 59.0
PYH2_k127_5253760_3 PFAM aminotransferase class V K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 436.0
PYH2_k127_5253760_4 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 415.0
PYH2_k127_5253760_5 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 345.0
PYH2_k127_5253760_6 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 322.0
PYH2_k127_5253760_7 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 307.0
PYH2_k127_5253760_8 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 312.0
PYH2_k127_5253760_9 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003623 290.0
PYH2_k127_529262_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.458e-236 736.0
PYH2_k127_529262_1 PFAM ROK family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 494.0
PYH2_k127_529262_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 438.0
PYH2_k127_529262_3 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 313.0
PYH2_k127_529262_4 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000004606 138.0
PYH2_k127_529262_5 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00006085 53.0
PYH2_k127_5362255_0 PFAM peptidase S58, DmpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 371.0
PYH2_k127_5362255_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001138 291.0
PYH2_k127_5362255_2 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000001255 228.0
PYH2_k127_5362255_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000001597 188.0
PYH2_k127_5362255_4 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000002849 130.0
PYH2_k127_5362255_6 AI-2E family transporter - - - 0.000000000002762 78.0
PYH2_k127_5363386_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 322.0
PYH2_k127_5363386_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 309.0
PYH2_k127_5363386_10 sequence-specific DNA binding K15539 - - 0.0000000000000000000006469 102.0
PYH2_k127_5363386_11 Peptidase family M23 - - - 0.0000000000000000000007301 103.0
PYH2_k127_5363386_12 GNAT acetyltransferase - - - 0.00000000000005011 81.0
PYH2_k127_5363386_2 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 299.0
PYH2_k127_5363386_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002863 266.0
PYH2_k127_5363386_4 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000009099 241.0
PYH2_k127_5363386_5 Methyltransferase domain K06987 - - 0.000000000000000000000000000000000000000000000000000000000001015 219.0
PYH2_k127_5363386_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000007864 214.0
PYH2_k127_5363386_7 acetyltransferase K00657 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000001769 190.0
PYH2_k127_5363386_8 - - - - 0.00000000000000000000000000000000000007489 154.0
PYH2_k127_5363386_9 pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000002722 103.0
PYH2_k127_5412140_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 423.0
PYH2_k127_5412140_1 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 290.0
PYH2_k127_5412140_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003216 262.0
PYH2_k127_5412140_3 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000003671 172.0
PYH2_k127_5412140_4 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000006451 109.0
PYH2_k127_5412280_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 9.297e-250 785.0
PYH2_k127_5412280_1 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 3.691e-224 707.0
PYH2_k127_5412280_10 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.000006086 52.0
PYH2_k127_5412280_2 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 2.997e-194 618.0
PYH2_k127_5412280_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 483.0
PYH2_k127_5412280_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 336.0
PYH2_k127_5412280_5 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 312.0
PYH2_k127_5412280_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001636 263.0
PYH2_k127_5412280_7 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000001145 173.0
PYH2_k127_5412280_8 heme binding - - - 0.0000000000000000000000000000000000001468 155.0
PYH2_k127_5412280_9 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000134 71.0
PYH2_k127_5417788_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 467.0
PYH2_k127_5417788_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 438.0
PYH2_k127_5417788_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 416.0
PYH2_k127_5417788_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 314.0
PYH2_k127_5417788_4 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
PYH2_k127_5417788_5 PFAM pentapeptide repeat protein - - - 0.000000000000000000000000001244 118.0
PYH2_k127_5417788_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000001359 108.0
PYH2_k127_5417788_7 Belongs to the 'phage' integrase family K04763 - - 0.000007294 54.0
PYH2_k127_5417788_8 - - - - 0.0003405 46.0
PYH2_k127_5485879_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 1.299e-255 798.0
PYH2_k127_5485879_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 507.0
PYH2_k127_5485879_2 formate dehydrogenase (NAD+) activity K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 405.0
PYH2_k127_5485879_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001132 291.0
PYH2_k127_5485879_4 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000001167 149.0
PYH2_k127_5485879_5 phosphorelay signal transduction system - - - 0.00000000000000000000001855 106.0
PYH2_k127_5558369_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000003812 156.0
PYH2_k127_5558369_1 Pkd domain containing protein - - - 0.000000000000000000000000000000000000006425 166.0
PYH2_k127_5558369_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000000000000000002991 109.0
PYH2_k127_5558369_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00002225 51.0
PYH2_k127_5602082_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.661e-296 922.0
PYH2_k127_5602082_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 4.925e-251 778.0
PYH2_k127_5602082_10 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 415.0
PYH2_k127_5602082_11 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 403.0
PYH2_k127_5602082_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 398.0
PYH2_k127_5602082_13 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 380.0
PYH2_k127_5602082_14 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 337.0
PYH2_k127_5602082_15 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 331.0
PYH2_k127_5602082_16 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 321.0
PYH2_k127_5602082_17 PFAM PfkB domain protein K16328 - 2.7.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 309.0
PYH2_k127_5602082_18 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 316.0
PYH2_k127_5602082_19 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 289.0
PYH2_k127_5602082_2 PFAM glycosidase PH1107-related K18785,K20885 - 2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 527.0
PYH2_k127_5602082_20 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004213 278.0
PYH2_k127_5602082_21 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005904 261.0
PYH2_k127_5602082_22 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000001038 211.0
PYH2_k127_5602082_23 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000001398 186.0
PYH2_k127_5602082_24 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000005904 169.0
PYH2_k127_5602082_25 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000004993 162.0
PYH2_k127_5602082_26 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000002477 146.0
PYH2_k127_5602082_27 Cold shock protein K03704 - - 0.00000000000000000000009256 100.0
PYH2_k127_5602082_28 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K14091,K15831 - - 0.00000006589 58.0
PYH2_k127_5602082_29 stress-induced mitochondrial fusion K04066,K07037,K17266 - - 0.00000007501 64.0
PYH2_k127_5602082_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 531.0
PYH2_k127_5602082_31 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.000002502 54.0
PYH2_k127_5602082_4 Acetyl xylan esterase (AXE1) K01060 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564 3.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 492.0
PYH2_k127_5602082_5 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 475.0
PYH2_k127_5602082_6 Tagatose 6 phosphate kinase K16371 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 452.0
PYH2_k127_5602082_7 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 446.0
PYH2_k127_5602082_8 Major facilitator Superfamily K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 426.0
PYH2_k127_5602082_9 Glycoside-hydrolase family GH114 K21006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 415.0
PYH2_k127_5661319_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1209.0
PYH2_k127_5661319_1 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688,K21298 - 2.4.1.20,2.4.1.333 0.0 1022.0
PYH2_k127_5661319_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000705 145.0
PYH2_k127_5661319_11 Virulence factor BrkB K07058 - - 0.000000000000000000000000000002795 131.0
PYH2_k127_5661319_12 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000009457 119.0
PYH2_k127_5661319_13 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000038 81.0
PYH2_k127_5661319_14 TPR Domain containing protein K12600 - - 0.0000000000001115 83.0
PYH2_k127_5661319_15 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000779 76.0
PYH2_k127_5661319_16 Protein of unknown function (DUF1269) - - - 0.0000003042 58.0
PYH2_k127_5661319_2 FtsX-like permease family K02004 - - 5.303e-207 677.0
PYH2_k127_5661319_3 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 624.0
PYH2_k127_5661319_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 584.0
PYH2_k127_5661319_5 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 334.0
PYH2_k127_5661319_6 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003245 257.0
PYH2_k127_5661319_7 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000134 166.0
PYH2_k127_5661319_8 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000009616 158.0
PYH2_k127_5661319_9 Histidine kinase - - - 0.00000000000000000000000000000000000002175 165.0
PYH2_k127_5671950_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2164.0
PYH2_k127_5671950_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.636e-284 897.0
PYH2_k127_5671950_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 532.0
PYH2_k127_5671950_3 glycosyl transferase family 28 K05841 - 2.4.1.173 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 505.0
PYH2_k127_5671950_4 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 447.0
PYH2_k127_5671950_5 O-methyltransferase activity K00545 - 2.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 302.0
PYH2_k127_5671950_6 acetyltransferase K00621 - 2.3.1.4 0.0000000000000000000000000000000000000000000000000000000001829 214.0
PYH2_k127_5671950_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000006831 177.0
PYH2_k127_5671950_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000009307 102.0
PYH2_k127_5671950_9 sh3 domain protein K01448 - 3.5.1.28 0.00004337 55.0
PYH2_k127_568336_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 562.0
PYH2_k127_568336_1 - - - - 0.00000000000003759 74.0
PYH2_k127_57014_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.075e-267 844.0
PYH2_k127_57014_1 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 9.657e-224 711.0
PYH2_k127_57014_10 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297 - 1.5.1.20 0.0000000000000000001207 103.0
PYH2_k127_57014_11 CBS domain - - - 0.0000001463 60.0
PYH2_k127_57014_2 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 3.562e-196 621.0
PYH2_k127_57014_3 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 535.0
PYH2_k127_57014_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 386.0
PYH2_k127_57014_5 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 333.0
PYH2_k127_57014_6 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000002599 255.0
PYH2_k127_57014_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000001993 216.0
PYH2_k127_57014_8 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000004281 193.0
PYH2_k127_57014_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001016 163.0
PYH2_k127_5761784_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 556.0
PYH2_k127_5761784_1 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 516.0
PYH2_k127_5761784_10 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000001221 211.0
PYH2_k127_5761784_11 related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
PYH2_k127_5761784_12 transport system permease K02057 - - 0.0000000000000000000000000000000000000000000000000000000006387 214.0
PYH2_k127_5761784_13 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
PYH2_k127_5761784_14 atpase related to the helicase subunit of the holliday junction resolvase - - - 0.0000000000000000000000000000000000000000000000000005436 191.0
PYH2_k127_5761784_15 uridine phosphorylase activity K00757,K01241,K03784 GO:0003674,GO:0003824,GO:0004850,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006218,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0022607,GO:0030955,GO:0031420,GO:0033554,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046108,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051259,GO:0051716,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1,2.4.2.3,3.2.2.4 0.000000000000000000000000000000000000000000000000001215 192.0
PYH2_k127_5761784_16 PFAM Inosine uridine-preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.00000000000000000000000000000000000002603 156.0
PYH2_k127_5761784_17 CAAX protease self-immunity - - - 0.000000000000000000000000000000000002186 147.0
PYH2_k127_5761784_18 - - - - 0.000000000000000000000000000000000004346 143.0
PYH2_k127_5761784_19 Acetylornithine deacetylase K01439,K05831 - 3.5.1.18 0.00000000000000000000000000000000001141 152.0
PYH2_k127_5761784_2 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 429.0
PYH2_k127_5761784_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000009548 132.0
PYH2_k127_5761784_21 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.000000000000000000000000000002842 126.0
PYH2_k127_5761784_22 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.00000000000000000000000000009352 127.0
PYH2_k127_5761784_23 Tellurite resistance protein TehB - - - 0.00000000000242 76.0
PYH2_k127_5761784_3 basic membrane K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 415.0
PYH2_k127_5761784_4 Protein of unknown function (DUF3029) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 406.0
PYH2_k127_5761784_5 transport system permease K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 334.0
PYH2_k127_5761784_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 318.0
PYH2_k127_5761784_7 Belongs to the IUNH family K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002837 286.0
PYH2_k127_5761784_8 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000116 237.0
PYH2_k127_5761784_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000004616 216.0
PYH2_k127_5802464_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 295.0
PYH2_k127_5802464_1 HEAT repeats K03301 - - 0.0000000000000000000000000000000000007186 155.0
PYH2_k127_5805439_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 398.0
PYH2_k127_5805439_1 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 312.0
PYH2_k127_5805439_2 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000001888 120.0
PYH2_k127_5805439_3 - - - - 0.0000006764 55.0
PYH2_k127_5823023_0 formate C-acetyltransferase glycine radical - - - 0.0 1223.0
PYH2_k127_5823023_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 614.0
PYH2_k127_5823023_2 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 590.0
PYH2_k127_5823023_3 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 427.0
PYH2_k127_5823023_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 400.0
PYH2_k127_5823023_5 PFAM photosystem I assembly BtpA K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 385.0
PYH2_k127_5823023_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 319.0
PYH2_k127_5823023_7 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002911 279.0
PYH2_k127_5823023_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001539 272.0
PYH2_k127_5823023_9 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000966 191.0
PYH2_k127_5849239_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.164e-314 972.0
PYH2_k127_5849239_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 560.0
PYH2_k127_5849239_10 Domain of unknown function (DUF1952) K03636 - - 0.00000001178 61.0
PYH2_k127_5849239_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 431.0
PYH2_k127_5849239_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 419.0
PYH2_k127_5849239_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
PYH2_k127_5849239_5 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000003837 228.0
PYH2_k127_5849239_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000004841 220.0
PYH2_k127_5849239_7 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.0000000000000000000000000000000000000002981 157.0
PYH2_k127_5849239_8 Sucrose-6F-phosphate phosphohydrolase - - - 0.000000000000000000000000000001244 132.0
PYH2_k127_5849239_9 TIGRFAM MoaD family protein K03636 - - 0.00000000000000000000001818 103.0
PYH2_k127_5863465_0 4Fe-4S dicluster domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.517e-268 828.0
PYH2_k127_5863465_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 380.0
PYH2_k127_5863465_2 nitrate reductase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 292.0
PYH2_k127_5863465_3 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 282.0
PYH2_k127_5863465_4 - - - - 0.000000000000000000000000000000000000000000000000000001511 197.0
PYH2_k127_5863465_6 cheY-homologous receiver domain - - - 0.000000007668 58.0
PYH2_k127_5870847_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 514.0
PYH2_k127_5870847_1 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000001995 203.0
PYH2_k127_5880185_0 Belongs to the carbamoyltransferase HypF family K04656 - - 9.735e-219 697.0
PYH2_k127_5880185_1 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 524.0
PYH2_k127_5880185_2 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 343.0
PYH2_k127_5880185_3 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000001413 158.0
PYH2_k127_5880185_4 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000000113 111.0
PYH2_k127_5899695_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 587.0
PYH2_k127_5899695_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 350.0
PYH2_k127_5899695_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
PYH2_k127_5899695_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000005133 167.0
PYH2_k127_5899695_4 - - - - 0.000000000000000000002458 104.0
PYH2_k127_5899695_5 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000003097 72.0
PYH2_k127_5899695_6 Sh3 type 3 domain protein K01361 - 3.4.21.96 0.000008001 58.0
PYH2_k127_5907553_0 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 428.0
PYH2_k127_5907553_1 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 346.0
PYH2_k127_5907553_10 Cellulose biosynthesis protein BcsQ K03496 - - 0.0007844 42.0
PYH2_k127_5907553_2 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 333.0
PYH2_k127_5907553_3 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001908 280.0
PYH2_k127_5907553_4 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000004567 267.0
PYH2_k127_5907553_5 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001175 251.0
PYH2_k127_5907553_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009619 230.0
PYH2_k127_5907553_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000004627 235.0
PYH2_k127_5907553_8 Histidine kinase-like ATPases - - - 0.0000000000367 76.0
PYH2_k127_5907553_9 diguanylate cyclase K19168 - - 0.000005795 59.0
PYH2_k127_595048_0 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 420.0
PYH2_k127_595048_1 Glycosyltransferase WbsX - - - 0.0000000000000000000009809 108.0
PYH2_k127_5962719_0 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002488 235.0
PYH2_k127_5962719_1 amidohydrolase K01845 - 5.4.3.8 0.0000000000000000000004872 106.0
PYH2_k127_5962719_2 B-1 B cell differentiation - - - 0.00001155 48.0
PYH2_k127_5967819_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1517.0
PYH2_k127_5967819_1 PA domain - - - 0.0 1219.0
PYH2_k127_5967819_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 334.0
PYH2_k127_5967819_11 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 336.0
PYH2_k127_5967819_12 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 321.0
PYH2_k127_5967819_13 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 314.0
PYH2_k127_5967819_14 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
PYH2_k127_5967819_15 transferase activity, transferring acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 309.0
PYH2_k127_5967819_16 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 300.0
PYH2_k127_5967819_17 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 282.0
PYH2_k127_5967819_18 Carbonic anhydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006633 273.0
PYH2_k127_5967819_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002674 288.0
PYH2_k127_5967819_2 ABC transporter transmembrane region K06147 - - 9.038e-251 790.0
PYH2_k127_5967819_20 heme binding K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007485 270.0
PYH2_k127_5967819_21 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000007268 249.0
PYH2_k127_5967819_22 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001552 237.0
PYH2_k127_5967819_23 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000002832 224.0
PYH2_k127_5967819_24 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001701 224.0
PYH2_k127_5967819_25 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000001759 216.0
PYH2_k127_5967819_26 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000166 209.0
PYH2_k127_5967819_27 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000003983 179.0
PYH2_k127_5967819_28 - - - - 0.000000000000000000000000000000000000000000000003461 180.0
PYH2_k127_5967819_29 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000001086 172.0
PYH2_k127_5967819_3 Endonuclease/Exonuclease/phosphatase family K07004 - - 4.235e-232 767.0
PYH2_k127_5967819_30 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000009991 166.0
PYH2_k127_5967819_31 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000000000000000000000721 160.0
PYH2_k127_5967819_32 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001113 160.0
PYH2_k127_5967819_33 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000003662 151.0
PYH2_k127_5967819_34 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000002674 145.0
PYH2_k127_5967819_35 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000002563 136.0
PYH2_k127_5967819_36 - - - - 0.00000000000000000000000000000003105 132.0
PYH2_k127_5967819_37 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000009993 129.0
PYH2_k127_5967819_38 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000001462 130.0
PYH2_k127_5967819_39 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000003587 115.0
PYH2_k127_5967819_4 aldo keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 479.0
PYH2_k127_5967819_40 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.0000000000000000000002232 109.0
PYH2_k127_5967819_41 - - - - 0.0000000000000000001145 96.0
PYH2_k127_5967819_42 - - - - 0.00000000000000001709 85.0
PYH2_k127_5967819_43 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000003862 74.0
PYH2_k127_5967819_44 - - - - 0.000000000205 67.0
PYH2_k127_5967819_45 - - - - 0.0000000002215 70.0
PYH2_k127_5967819_46 acetyltransferase - - - 0.000000001749 66.0
PYH2_k127_5967819_47 DinB superfamily - - - 0.000000002547 65.0
PYH2_k127_5967819_48 Auxin binding protein - - - 0.0009916 48.0
PYH2_k127_5967819_5 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 475.0
PYH2_k127_5967819_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 415.0
PYH2_k127_5967819_7 PFAM Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 388.0
PYH2_k127_5967819_8 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 388.0
PYH2_k127_5967819_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 370.0
PYH2_k127_5989097_0 PFAM ABC transporter related K06158 - - 2.515e-212 678.0
PYH2_k127_5989097_1 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 367.0
PYH2_k127_5989097_2 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 359.0
PYH2_k127_5989097_3 VIT family - - - 0.00000000000000000000000000000003915 135.0
PYH2_k127_5989097_4 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.000000002122 60.0
PYH2_k127_6022696_0 Aldehyde dehydrogenase 16 family member A1 K00128 - 1.2.1.3 0.0 1068.0
PYH2_k127_6022696_1 4Fe-4S binding domain - - - 1.843e-207 651.0
PYH2_k127_6022696_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008592 244.0
PYH2_k127_6022696_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000004931 141.0
PYH2_k127_6022696_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000000007194 131.0
PYH2_k127_6022696_13 methyltransferase - - - 0.0000000000000000000000000004278 122.0
PYH2_k127_6022696_14 - - - - 0.00000000000000000000004491 106.0
PYH2_k127_6022696_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000002483 94.0
PYH2_k127_6022696_17 gas vesicle protein - - - 0.0000000000000000000265 93.0
PYH2_k127_6022696_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 477.0
PYH2_k127_6022696_3 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 443.0
PYH2_k127_6022696_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 390.0
PYH2_k127_6022696_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 321.0
PYH2_k127_6022696_6 PFAM TrkA-N domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 319.0
PYH2_k127_6022696_7 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 321.0
PYH2_k127_6022696_8 PFAM Stage II sporulation E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000635 284.0
PYH2_k127_6022696_9 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001432 283.0
PYH2_k127_6023118_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 2.648e-196 621.0
PYH2_k127_6023118_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 561.0
PYH2_k127_6023118_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001943 248.0
PYH2_k127_6023118_3 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000001532 76.0
PYH2_k127_6023118_4 Ketopantoate hydroxymethyltransferase K00606 - 2.1.2.11 0.0000000001375 63.0
PYH2_k127_6024836_0 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 284.0
PYH2_k127_6024836_1 ATPase AAA-2 domain protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
PYH2_k127_6024836_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000001485 196.0
PYH2_k127_6024836_4 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000000000000000001968 113.0
PYH2_k127_6030730_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1179.0
PYH2_k127_6030730_1 PFAM ABC transporter related K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 573.0
PYH2_k127_6030730_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 409.0
PYH2_k127_6041965_0 PFAM Cation efflux - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002605 250.0
PYH2_k127_6041965_1 Succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000007579 233.0
PYH2_k127_6041965_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000006995 124.0
PYH2_k127_6041965_3 repeat protein - - - 0.0000000008801 60.0
PYH2_k127_6041965_4 PFAM Alpha beta hydrolase of - - - 0.0005841 49.0
PYH2_k127_6050927_0 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000006642 176.0
PYH2_k127_6055760_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002574 237.0
PYH2_k127_6055760_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000002945 157.0
PYH2_k127_6088289_0 PFAM Class II aldolase K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 318.0
PYH2_k127_6088289_1 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009215 290.0
PYH2_k127_6088289_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000007926 105.0
PYH2_k127_6110385_0 Ferrous iron transport protein B C terminus K04759 - - 8.815e-238 754.0
PYH2_k127_6110385_1 Protein of unknown function (DUF2892) K03671 - - 0.0000000000000000000000000000000000000000000000000009488 188.0
PYH2_k127_6110385_2 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000000000000000002498 174.0
PYH2_k127_6110385_3 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000000000000008112 171.0
PYH2_k127_6110385_4 Protein of unknown function (DUF2892) - - - 0.00000000001753 70.0
PYH2_k127_6110385_5 PFAM FeoA family protein K04758 - - 0.00000000006788 66.0
PYH2_k127_6110385_6 nitrite reductase, copper-containing K00368 - 1.7.2.1 0.0003345 45.0
PYH2_k127_619193_0 SMART Elongator protein 3 MiaB NifB - - - 4.211e-248 778.0
PYH2_k127_619193_1 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 351.0
PYH2_k127_619193_2 Pkd domain containing protein K12567 - 2.7.11.1 0.00000000007276 64.0
PYH2_k127_6208563_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 300.0
PYH2_k127_6208563_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000009265 246.0
PYH2_k127_6211784_0 Glycosyltransferase 36 associated - - - 0.0 1350.0
PYH2_k127_6211784_1 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 0.0 1096.0
PYH2_k127_6211784_10 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 494.0
PYH2_k127_6211784_11 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 491.0
PYH2_k127_6211784_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 481.0
PYH2_k127_6211784_13 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 447.0
PYH2_k127_6211784_14 Cellulase (glycosyl hydrolase family 5) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 446.0
PYH2_k127_6211784_15 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 387.0
PYH2_k127_6211784_16 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 383.0
PYH2_k127_6211784_17 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 384.0
PYH2_k127_6211784_18 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 362.0
PYH2_k127_6211784_19 Family 4 glycosyl hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 373.0
PYH2_k127_6211784_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 601.0
PYH2_k127_6211784_20 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 351.0
PYH2_k127_6211784_21 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
PYH2_k127_6211784_22 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 329.0
PYH2_k127_6211784_23 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 317.0
PYH2_k127_6211784_24 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 301.0
PYH2_k127_6211784_25 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003783 301.0
PYH2_k127_6211784_26 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
PYH2_k127_6211784_27 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 264.0
PYH2_k127_6211784_28 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000001398 237.0
PYH2_k127_6211784_29 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000000002294 233.0
PYH2_k127_6211784_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 598.0
PYH2_k127_6211784_30 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000005628 215.0
PYH2_k127_6211784_31 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000004152 211.0
PYH2_k127_6211784_32 homoserine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000008485 213.0
PYH2_k127_6211784_33 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000008527 209.0
PYH2_k127_6211784_34 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000004373 190.0
PYH2_k127_6211784_35 - - - - 0.000000000000000000000000000000000000000000000000006013 193.0
PYH2_k127_6211784_36 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000001038 197.0
PYH2_k127_6211784_37 Bacterial transferase hexapeptide (three repeats) K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000289 187.0
PYH2_k127_6211784_38 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000006052 182.0
PYH2_k127_6211784_39 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000001906 164.0
PYH2_k127_6211784_4 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 578.0
PYH2_k127_6211784_40 EamA-like transporter family - - - 0.0000000000000000000000000000000000000001281 161.0
PYH2_k127_6211784_41 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000005151 150.0
PYH2_k127_6211784_42 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000216 141.0
PYH2_k127_6211784_43 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000004161 143.0
PYH2_k127_6211784_44 Nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000009536 133.0
PYH2_k127_6211784_45 AAA domain - - - 0.00000000000000000000000000006783 117.0
PYH2_k127_6211784_46 Oxidoreductase - - - 0.000000000000000000000000005419 123.0
PYH2_k127_6211784_47 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000009338 111.0
PYH2_k127_6211784_49 uridine kinase - - - 0.00000000000000000000000003499 116.0
PYH2_k127_6211784_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 584.0
PYH2_k127_6211784_50 Regulatory protein, FmdB family - - - 0.000000000000000001925 88.0
PYH2_k127_6211784_52 Ig-like domain from next to BRCA1 gene - - - 0.00000000000002433 81.0
PYH2_k127_6211784_53 AAA domain - - - 0.0000000004529 62.0
PYH2_k127_6211784_54 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000001313 60.0
PYH2_k127_6211784_55 AAA domain - - - 0.000000002223 60.0
PYH2_k127_6211784_6 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 576.0
PYH2_k127_6211784_7 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 551.0
PYH2_k127_6211784_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 520.0
PYH2_k127_6211784_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 511.0
PYH2_k127_6229269_0 helix_turn _helix lactose operon repressor K05499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001303 274.0
PYH2_k127_6229269_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
PYH2_k127_6229269_2 tagaturonate epimerase K21619 - 5.1.2.7 0.0002794 47.0
PYH2_k127_6232924_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 597.0
PYH2_k127_6232924_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000353 206.0
PYH2_k127_6332955_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1376.0
PYH2_k127_6332955_1 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 591.0
PYH2_k127_6332955_10 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 382.0
PYH2_k127_6332955_11 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 360.0
PYH2_k127_6332955_12 protein histidine kinase activity K10819 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 348.0
PYH2_k127_6332955_13 PFAM Metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 324.0
PYH2_k127_6332955_14 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 293.0
PYH2_k127_6332955_15 PFAM response regulator receiver K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
PYH2_k127_6332955_16 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007395 262.0
PYH2_k127_6332955_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001396 247.0
PYH2_k127_6332955_18 sequence-specific DNA binding K03718,K03719 - - 0.0000000000000000000000000000000000000000000004697 170.0
PYH2_k127_6332955_19 Nitroreductase family - - - 0.0000000000000000000000000000000000000000009126 165.0
PYH2_k127_6332955_2 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 584.0
PYH2_k127_6332955_20 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000001525 151.0
PYH2_k127_6332955_3 PFAM extracellular solute-binding protein family 1 K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 533.0
PYH2_k127_6332955_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 532.0
PYH2_k127_6332955_5 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 527.0
PYH2_k127_6332955_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 518.0
PYH2_k127_6332955_7 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 494.0
PYH2_k127_6332955_8 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 467.0
PYH2_k127_6332955_9 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 426.0
PYH2_k127_6404884_0 AcrB/AcrD/AcrF family - - - 0.0 1122.0
PYH2_k127_6404884_1 cation efflux system protein (Heavy metal efflux pump) - - - 3.998e-287 915.0
PYH2_k127_6404884_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000009125 169.0
PYH2_k127_6404884_11 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000104 171.0
PYH2_k127_6404884_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000007829 118.0
PYH2_k127_6404884_13 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000249 100.0
PYH2_k127_6404884_14 polysaccharide catabolic process K01179,K04771 - 3.2.1.4,3.4.21.107 0.0000000000000000001127 105.0
PYH2_k127_6404884_15 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000003359 98.0
PYH2_k127_6404884_16 response regulator receiver - - - 0.000000000000000003495 89.0
PYH2_k127_6404884_17 COG2801 Transposase and inactivated derivatives - - - 0.000000000001025 70.0
PYH2_k127_6404884_18 COG2801 Transposase and inactivated derivatives - - - 0.000000000001958 66.0
PYH2_k127_6404884_19 COG2801 Transposase and inactivated derivatives - - - 0.00000000002939 65.0
PYH2_k127_6404884_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 489.0
PYH2_k127_6404884_20 ATP binding K19171 - - 0.000000005044 58.0
PYH2_k127_6404884_21 Integrase core domain - - - 0.00000001249 59.0
PYH2_k127_6404884_22 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00002338 53.0
PYH2_k127_6404884_23 guanyl-nucleotide exchange factor activity K01387,K12287 - 3.4.24.3 0.0007473 53.0
PYH2_k127_6404884_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 357.0
PYH2_k127_6404884_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 338.0
PYH2_k127_6404884_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 317.0
PYH2_k127_6404884_6 1-deoxy-D-xylulose-5-phosphate synthase K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002045 285.0
PYH2_k127_6404884_7 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002214 285.0
PYH2_k127_6404884_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005154 274.0
PYH2_k127_6404884_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000001976 243.0
PYH2_k127_6406705_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 311.0
PYH2_k127_6406705_2 Beta-lactamase class C - - - 0.000000623 55.0
PYH2_k127_6406705_3 PFAM Beta-lactamase K18988 - 3.4.16.4 0.00004407 50.0
PYH2_k127_6406705_4 hydrolase activity, acting on ester bonds - - - 0.0002688 48.0
PYH2_k127_6429374_0 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 1.057e-264 856.0
PYH2_k127_6429374_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.51e-224 698.0
PYH2_k127_6429374_10 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 423.0
PYH2_k127_6429374_11 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 402.0
PYH2_k127_6429374_12 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
PYH2_k127_6429374_13 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 325.0
PYH2_k127_6429374_14 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 322.0
PYH2_k127_6429374_15 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001857 289.0
PYH2_k127_6429374_16 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
PYH2_k127_6429374_17 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000004069 231.0
PYH2_k127_6429374_18 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000002607 205.0
PYH2_k127_6429374_19 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.0000000000000000000000000000000000001281 149.0
PYH2_k127_6429374_2 Beta-Casp domain K07576 - - 1.791e-198 627.0
PYH2_k127_6429374_20 MafB19-like deaminase K11991 - 3.5.4.33 0.00000000000000000000000000000005039 133.0
PYH2_k127_6429374_21 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000009789 126.0
PYH2_k127_6429374_22 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000005054 136.0
PYH2_k127_6429374_23 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000003966 86.0
PYH2_k127_6429374_3 Gamma-glutamyltranspeptidase 2-like K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 580.0
PYH2_k127_6429374_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 508.0
PYH2_k127_6429374_5 Cytochrome bd-type quinol oxidase, subunit 1 K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 484.0
PYH2_k127_6429374_6 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 448.0
PYH2_k127_6429374_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 441.0
PYH2_k127_6429374_8 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 430.0
PYH2_k127_6429374_9 PFAM Cytochrome bd ubiquinol oxidase, subunit II K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
PYH2_k127_6454828_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K09971,K17062 - - 0.00000000000000000000000000233 125.0
PYH2_k127_6454828_1 peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000001949 93.0
PYH2_k127_6454828_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000002123 91.0
PYH2_k127_6494396_0 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 418.0
PYH2_k127_6494396_1 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 383.0
PYH2_k127_6494396_11 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000002807 57.0
PYH2_k127_6494396_2 L-asparaginase II K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 385.0
PYH2_k127_6494396_3 ATPase AAA-2 domain protein K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 377.0
PYH2_k127_6494396_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
PYH2_k127_6494396_5 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 303.0
PYH2_k127_6494396_6 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000008242 222.0
PYH2_k127_6494396_7 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000000000000000000000000000000002317 196.0
PYH2_k127_6494396_8 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000000000000000000002238 157.0
PYH2_k127_6494396_9 - - - - 0.000000000000000000000000001393 119.0
PYH2_k127_6502776_0 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003356 276.0
PYH2_k127_6502776_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000008518 79.0
PYH2_k127_6502776_2 Protein tyrosine kinase K08884 - 2.7.11.1 0.000238 52.0
PYH2_k127_6520532_0 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 571.0
PYH2_k127_6520532_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
PYH2_k127_6520532_2 - - - - 0.0000000000000000000000000000000000001974 152.0
PYH2_k127_6520532_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000001523 100.0
PYH2_k127_6522637_0 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 342.0
PYH2_k127_6523119_0 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 369.0
PYH2_k127_6523119_1 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 351.0
PYH2_k127_6523119_2 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 284.0
PYH2_k127_6523119_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000003745 235.0
PYH2_k127_6523119_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001278 190.0
PYH2_k127_6523119_5 PFAM zinc finger, SWIM domain protein - - - 0.0000000000000000000000000004236 114.0
PYH2_k127_6523119_6 SMART helix-turn-helix domain protein K15539 - - 0.00000000000000000000000001705 116.0
PYH2_k127_6554999_0 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000000000000001276 175.0
PYH2_k127_6596455_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0 1049.0
PYH2_k127_6596455_1 Heat shock 70 kDa protein K04043 - - 6.662e-309 955.0
PYH2_k127_6596455_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000002099 211.0
PYH2_k127_6596455_11 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000002182 199.0
PYH2_k127_6596455_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000007523 166.0
PYH2_k127_6596455_13 - - - - 0.0000000000000000000000000000000000002195 159.0
PYH2_k127_6596455_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000005253 148.0
PYH2_k127_6596455_15 Protein kinase domain - - - 0.000000000000000000000000001058 125.0
PYH2_k127_6596455_16 Cyclic nucleotide-monophosphate binding domain K09766 - - 0.000000000000000002379 94.0
PYH2_k127_6596455_17 - - - - 0.000000000000006369 82.0
PYH2_k127_6596455_2 E1-E2 ATPase K01537,K12953 - 3.6.3.8 3.408e-283 896.0
PYH2_k127_6596455_3 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.135e-252 784.0
PYH2_k127_6596455_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.878e-218 685.0
PYH2_k127_6596455_5 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 533.0
PYH2_k127_6596455_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 488.0
PYH2_k127_6596455_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 435.0
PYH2_k127_6596455_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 400.0
PYH2_k127_6596455_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 338.0
PYH2_k127_6611318_0 Copper binding proteins, plastocyanin/azurin family K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 458.0
PYH2_k127_6611318_1 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006322 272.0
PYH2_k127_6611318_3 - - - - 0.0000000000000000000000000000000000000000000002546 173.0
PYH2_k127_6611318_4 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000005048 140.0
PYH2_k127_6611318_5 - - - - 0.0000000000000000000000000000008088 127.0
PYH2_k127_6611318_6 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000009902 132.0
PYH2_k127_6611318_7 metal-dependent membrane protease K07052 - - 0.000000000000000000000000000001292 133.0
PYH2_k127_6611318_8 FR47-like protein - - - 0.0000000000000000000006812 106.0
PYH2_k127_6616028_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000001549 164.0
PYH2_k127_6616028_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000002059 171.0
PYH2_k127_6616028_2 short-chain dehydrogenase K18337 - 1.1.1.173,1.1.1.377,1.1.1.378 0.000000000000000000000009207 107.0
PYH2_k127_6616028_3 PFAM short-chain dehydrogenase reductase SDR K00068,K03366,K08261 - 1.1.1.140,1.1.1.304,1.1.1.76,1.1.99.21 0.000001624 53.0
PYH2_k127_6628998_0 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 526.0
PYH2_k127_6628998_1 Sulfate permease K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 381.0
PYH2_k127_6628998_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004775 212.0
PYH2_k127_6628998_3 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000009606 169.0
PYH2_k127_6628998_4 Major facilitator superfamily - - - 0.000000000000000000000005561 117.0
PYH2_k127_6628998_5 Protein of unknown function (DUF1269) - - - 0.00000003274 62.0
PYH2_k127_6633275_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1206.0
PYH2_k127_6633275_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 557.0
PYH2_k127_6633275_10 Flavin containing amine oxidoreductase K15745 - 1.3.99.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 476.0
PYH2_k127_6633275_11 PFAM Cytochrome P450 - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 444.0
PYH2_k127_6633275_12 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 436.0
PYH2_k127_6633275_13 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 432.0
PYH2_k127_6633275_14 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 362.0
PYH2_k127_6633275_15 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
PYH2_k127_6633275_16 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 348.0
PYH2_k127_6633275_17 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 340.0
PYH2_k127_6633275_18 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 339.0
PYH2_k127_6633275_19 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 330.0
PYH2_k127_6633275_2 ABC transporter K02056,K06400 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 539.0
PYH2_k127_6633275_20 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 331.0
PYH2_k127_6633275_21 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 293.0
PYH2_k127_6633275_22 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000000000000000000000000000000000001231 218.0
PYH2_k127_6633275_23 TIGRFAM lycopene cyclase domain K22502 - 5.5.1.19 0.00000000000000000000000000000000000000003982 161.0
PYH2_k127_6633275_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000007813 162.0
PYH2_k127_6633275_25 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000004165 152.0
PYH2_k127_6633275_26 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000003057 154.0
PYH2_k127_6633275_27 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000002577 109.0
PYH2_k127_6633275_28 permease - - - 0.0000000000000000004707 100.0
PYH2_k127_6633275_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 529.0
PYH2_k127_6633275_4 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 507.0
PYH2_k127_6633275_5 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 503.0
PYH2_k127_6633275_6 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 490.0
PYH2_k127_6633275_7 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 482.0
PYH2_k127_6633275_8 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 476.0
PYH2_k127_6633275_9 DNA photolyase domain protein K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 473.0
PYH2_k127_6638116_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1813.0
PYH2_k127_6638116_1 FGGY family of carbohydrate kinases, N-terminal domain - - - 2.158e-253 789.0
PYH2_k127_6638116_10 TOBE domain K02062,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 347.0
PYH2_k127_6638116_11 energy transducer activity K03531,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 302.0
PYH2_k127_6638116_12 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006289 282.0
PYH2_k127_6638116_13 Nodulation protein S (NodS) K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000009642 228.0
PYH2_k127_6638116_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000002095 224.0
PYH2_k127_6638116_15 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
PYH2_k127_6638116_16 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000005427 186.0
PYH2_k127_6638116_17 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000002548 182.0
PYH2_k127_6638116_18 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000000003645 187.0
PYH2_k127_6638116_19 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000003286 184.0
PYH2_k127_6638116_2 amino acid K03294 - - 1.534e-236 749.0
PYH2_k127_6638116_20 Protein of unknown function (DUF402) K07586 - - 0.000000000000000000000000000000000001973 144.0
PYH2_k127_6638116_21 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000001971 135.0
PYH2_k127_6638116_22 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000005644 132.0
PYH2_k127_6638116_23 response to heat K03668 - - 0.000000000000000000000000005295 125.0
PYH2_k127_6638116_24 Transglycosylase associated protein - - - 0.0000000000000000000000002116 107.0
PYH2_k127_6638116_25 LysM domain K07273,K22278 - 3.5.1.104 0.00000000000000000000007175 108.0
PYH2_k127_6638116_26 Ribosomal protein S21 K02970 - - 0.0000000000000000005752 87.0
PYH2_k127_6638116_27 META domain - - - 0.0000000000000001722 92.0
PYH2_k127_6638116_28 cellulose binding - - - 0.00000000000002271 86.0
PYH2_k127_6638116_29 SpoVT / AbrB like domain K07172 - - 0.00001327 53.0
PYH2_k127_6638116_3 histidine kinase A domain protein - - - 1.527e-197 640.0
PYH2_k127_6638116_30 PFAM Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 0.0001589 49.0
PYH2_k127_6638116_4 Binding-protein-dependent transport system inner membrane component K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 529.0
PYH2_k127_6638116_5 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 438.0
PYH2_k127_6638116_6 Bacterial extracellular solute-binding protein K02064 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 439.0
PYH2_k127_6638116_7 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 404.0
PYH2_k127_6638116_8 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 401.0
PYH2_k127_6638116_9 metallophosphoesterase K07096,K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
PYH2_k127_664197_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 8.597e-216 679.0
PYH2_k127_664197_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 562.0
PYH2_k127_664197_10 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000005594 227.0
PYH2_k127_664197_11 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000001072 221.0
PYH2_k127_664197_12 Transcriptional regulator IclR - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
PYH2_k127_664197_13 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000379 204.0
PYH2_k127_664197_14 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000005306 184.0
PYH2_k127_664197_15 Transcriptional regulator K13641 - - 0.0000000000000000000000000000000000000000000002827 177.0
PYH2_k127_664197_16 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000001989 179.0
PYH2_k127_664197_17 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000002713 166.0
PYH2_k127_664197_18 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000003894 165.0
PYH2_k127_664197_19 Nitroreductase family - - - 0.000000000000000000000008655 109.0
PYH2_k127_664197_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 534.0
PYH2_k127_664197_20 4Fe-4S binding domain - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.000000000002818 69.0
PYH2_k127_664197_21 Mannose-6-phosphate isomerase - - - 0.00000000001282 70.0
PYH2_k127_664197_22 PFAM ThiamineS - - - 0.0000002628 55.0
PYH2_k127_664197_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 476.0
PYH2_k127_664197_4 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 391.0
PYH2_k127_664197_5 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 384.0
PYH2_k127_664197_6 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
PYH2_k127_664197_7 Glycolate oxidase K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 354.0
PYH2_k127_664197_8 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002299 266.0
PYH2_k127_664197_9 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000557 233.0
PYH2_k127_6702631_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 0.0 1044.0
PYH2_k127_6702631_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.424e-217 700.0
PYH2_k127_6702631_10 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 372.0
PYH2_k127_6702631_11 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 343.0
PYH2_k127_6702631_12 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 338.0
PYH2_k127_6702631_13 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 325.0
PYH2_k127_6702631_14 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 296.0
PYH2_k127_6702631_15 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001052 286.0
PYH2_k127_6702631_16 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001557 278.0
PYH2_k127_6702631_17 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
PYH2_k127_6702631_18 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
PYH2_k127_6702631_19 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000007227 206.0
PYH2_k127_6702631_2 DNA helicase - - - 2.023e-211 678.0
PYH2_k127_6702631_20 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000001093 207.0
PYH2_k127_6702631_21 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) - - - 0.00000000000000000000000000000000000000000000000000000001503 206.0
PYH2_k127_6702631_22 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000003683 209.0
PYH2_k127_6702631_23 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000413 188.0
PYH2_k127_6702631_24 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.00000000000000000000000000000000000000000000004086 179.0
PYH2_k127_6702631_25 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000004849 160.0
PYH2_k127_6702631_26 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000003511 145.0
PYH2_k127_6702631_27 phosphorelay signal transduction system - - - 0.000000000000000000000000000000001739 134.0
PYH2_k127_6702631_28 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000001167 143.0
PYH2_k127_6702631_29 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000009913 122.0
PYH2_k127_6702631_3 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 2.287e-211 663.0
PYH2_k127_6702631_31 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000004281 113.0
PYH2_k127_6702631_32 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000008535 97.0
PYH2_k127_6702631_33 pyrroloquinoline quinone binding K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000001035 86.0
PYH2_k127_6702631_34 Belongs to the BI1 family K06890 - - 0.0000000000000002032 86.0
PYH2_k127_6702631_35 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000003374 85.0
PYH2_k127_6702631_36 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000004877 81.0
PYH2_k127_6702631_37 - - - - 0.0000000000001016 79.0
PYH2_k127_6702631_38 META domain - - - 0.00000000002074 72.0
PYH2_k127_6702631_39 Belongs to the BI1 family K06890 - - 0.00000000003018 65.0
PYH2_k127_6702631_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 610.0
PYH2_k127_6702631_40 PFAM GCN5-related N-acetyltransferase - - - 0.00000000006121 68.0
PYH2_k127_6702631_41 Belongs to the 'phage' integrase family K04763 - - 0.00000008585 54.0
PYH2_k127_6702631_5 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 462.0
PYH2_k127_6702631_6 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 450.0
PYH2_k127_6702631_7 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 428.0
PYH2_k127_6702631_8 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 398.0
PYH2_k127_6702631_9 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 381.0
PYH2_k127_6726404_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.503e-274 865.0
PYH2_k127_6726404_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.819e-220 689.0
PYH2_k127_6726404_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 479.0
PYH2_k127_6726404_3 oligosaccharyl transferase activity - - - 0.000001267 53.0
PYH2_k127_6730593_0 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 535.0
PYH2_k127_6730593_1 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 351.0
PYH2_k127_6730593_2 PFAM cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 319.0
PYH2_k127_6730593_3 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000004382 178.0
PYH2_k127_6730593_4 Nacht domain K13730 - - 0.000000000000000000000000000000000000001226 156.0
PYH2_k127_6730593_5 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000000000001326 144.0
PYH2_k127_6772998_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4e-323 1006.0
PYH2_k127_6772998_1 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 1.481e-292 914.0
PYH2_k127_6772998_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 417.0
PYH2_k127_6772998_11 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 409.0
PYH2_k127_6772998_12 transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 367.0
PYH2_k127_6772998_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 363.0
PYH2_k127_6772998_14 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 363.0
PYH2_k127_6772998_15 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 343.0
PYH2_k127_6772998_16 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 340.0
PYH2_k127_6772998_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 312.0
PYH2_k127_6772998_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003311 271.0
PYH2_k127_6772998_19 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001681 276.0
PYH2_k127_6772998_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.763e-225 711.0
PYH2_k127_6772998_20 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000382 256.0
PYH2_k127_6772998_21 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001542 223.0
PYH2_k127_6772998_22 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000001666 222.0
PYH2_k127_6772998_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000015 148.0
PYH2_k127_6772998_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000003225 122.0
PYH2_k127_6772998_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000005552 115.0
PYH2_k127_6772998_28 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000004491 96.0
PYH2_k127_6772998_29 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000001384 87.0
PYH2_k127_6772998_3 Beta-eliminating lyase - - - 6.477e-209 658.0
PYH2_k127_6772998_30 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000004892 80.0
PYH2_k127_6772998_4 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.533e-199 634.0
PYH2_k127_6772998_5 PFAM extracellular solute-binding protein, family 5 K02035 - - 6.781e-198 632.0
PYH2_k127_6772998_6 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 579.0
PYH2_k127_6772998_7 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 536.0
PYH2_k127_6772998_8 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 450.0
PYH2_k127_6772998_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 434.0
PYH2_k127_6792062_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 604.0
PYH2_k127_6792062_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 556.0
PYH2_k127_6792062_10 WD-40 repeat - - - 0.0000000000000000000000000008297 127.0
PYH2_k127_6792062_12 CAAX protease self-immunity K07052 - - 0.000000000000000000005768 104.0
PYH2_k127_6792062_13 - - - - 0.00000000000000000001208 96.0
PYH2_k127_6792062_14 PFAM SMC domain protein K03546 - - 0.0000000000000431 72.0
PYH2_k127_6792062_15 AntiSigma factor - - - 0.00000000003101 76.0
PYH2_k127_6792062_17 domain, Protein - - - 0.000004125 59.0
PYH2_k127_6792062_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 545.0
PYH2_k127_6792062_3 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 322.0
PYH2_k127_6792062_4 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004608 251.0
PYH2_k127_6792062_5 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000427 229.0
PYH2_k127_6792062_6 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000002846 200.0
PYH2_k127_6792062_7 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000008554 188.0
PYH2_k127_6792062_8 phosphatidylinositol metabolic process - - - 0.0000000000000000000000000000000000000000000001276 186.0
PYH2_k127_6792062_9 PFAM Cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000002955 137.0
PYH2_k127_6894251_0 Neurotransmitter-gated ion-channel ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 489.0
PYH2_k127_6894251_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 422.0
PYH2_k127_6894251_10 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02029,K02030 - - 0.0000000000000000000000000000009236 140.0
PYH2_k127_6894251_11 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000001445 115.0
PYH2_k127_6894251_12 Ion channel - - - 0.0000000000000000002387 92.0
PYH2_k127_6894251_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000007657 83.0
PYH2_k127_6894251_14 Ig-like domain from next to BRCA1 gene - - - 0.000000000000001228 91.0
PYH2_k127_6894251_15 META domain - - - 0.000000000000003225 82.0
PYH2_k127_6894251_16 Phosphoprotein phosphatase K14819 GO:0000003,GO:0000027,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0008138,GO:0008150,GO:0008152,GO:0009272,GO:0009653,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010494,GO:0010506,GO:0010508,GO:0010638,GO:0010927,GO:0016043,GO:0016239,GO:0016241,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030154,GO:0030435,GO:0030437,GO:0030476,GO:0030684,GO:0030687,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0032991,GO:0033043,GO:0034293,GO:0034622,GO:0035335,GO:0035556,GO:0035770,GO:0036211,GO:0036464,GO:0042244,GO:0042254,GO:0042255,GO:0042273,GO:0042546,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0043935,GO:0044085,GO:0044087,GO:0044088,GO:0044089,GO:0044090,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045229,GO:0048468,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051321,GO:0051704,GO:0051716,GO:0065003,GO:0065007,GO:0070590,GO:0070591,GO:0070726,GO:0070925,GO:0071554,GO:0071555,GO:0071704,GO:0071826,GO:0071840,GO:0071852,GO:0071940,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1903046,GO:1990904,GO:2000785,GO:2000786 3.1.3.16,3.1.3.48 0.0000005681 59.0
PYH2_k127_6894251_2 H( )-transporting two-sector ATPase K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 404.0
PYH2_k127_6894251_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 326.0
PYH2_k127_6894251_4 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 301.0
PYH2_k127_6894251_5 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
PYH2_k127_6894251_6 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000004569 221.0
PYH2_k127_6894251_7 COG0569 K transport systems, NAD-binding component K03499 - - 0.000000000000000000000000000000000000000000000000001287 190.0
PYH2_k127_6894251_8 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000008771 182.0
PYH2_k127_6894251_9 diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000005841 165.0
PYH2_k127_7034210_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.639e-196 622.0
PYH2_k127_7034210_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 443.0
PYH2_k127_7034210_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 414.0
PYH2_k127_7034210_3 SMART helix-turn-helix domain protein K15539 - - 0.0000000000000000000000000000000006081 140.0
PYH2_k127_7036741_0 myo-inosose-2 dehydratase activity K10709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 262.0
PYH2_k127_7036741_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000001626 161.0
PYH2_k127_707925_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 427.0
PYH2_k127_707925_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 350.0
PYH2_k127_707925_2 CAAX amino Terminal protease family protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000002458 223.0
PYH2_k127_707925_3 glucuronate isomerase activity K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000002995 180.0
PYH2_k127_707925_4 Glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000000002427 157.0
PYH2_k127_707925_5 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000157 145.0
PYH2_k127_7080624_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1450.0
PYH2_k127_7080624_1 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0 1151.0
PYH2_k127_7080624_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
PYH2_k127_7080624_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 380.0
PYH2_k127_7080624_12 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 335.0
PYH2_k127_7080624_13 inorganic diphosphatase activity K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 327.0
PYH2_k127_7080624_14 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 331.0
PYH2_k127_7080624_15 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000221 263.0
PYH2_k127_7080624_16 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000138 254.0
PYH2_k127_7080624_17 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000003636 237.0
PYH2_k127_7080624_18 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000004806 239.0
PYH2_k127_7080624_19 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
PYH2_k127_7080624_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 6.698e-293 919.0
PYH2_k127_7080624_20 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000003457 221.0
PYH2_k127_7080624_21 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
PYH2_k127_7080624_22 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000001414 213.0
PYH2_k127_7080624_23 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000004706 214.0
PYH2_k127_7080624_24 - - - - 0.000000000000000000000000000000000000000000000003574 181.0
PYH2_k127_7080624_25 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000496 178.0
PYH2_k127_7080624_26 HTH-like domain K07497 - - 0.000000000000000000000000000000000000004341 150.0
PYH2_k127_7080624_27 SLBB domain K02237 - - 0.00000000000000000000000000000000004953 140.0
PYH2_k127_7080624_28 SCP-2 sterol transfer family - - - 0.00000000000000000000000002156 113.0
PYH2_k127_7080624_29 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000001499 100.0
PYH2_k127_7080624_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.295e-233 731.0
PYH2_k127_7080624_30 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619,K07755 - 1.20.4.1,2.1.1.137,2.3.1.1 0.00000000000000001702 89.0
PYH2_k127_7080624_31 Sulphur transport K07112 - - 0.00000000000000004198 87.0
PYH2_k127_7080624_32 Integrase core domain protein - - - 0.0000000002066 65.0
PYH2_k127_7080624_33 Integrase core domain protein K07497 - - 0.0000000857 53.0
PYH2_k127_7080624_34 transposase activity K07483,K07497 - - 0.0000003984 57.0
PYH2_k127_7080624_35 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000006042 60.0
PYH2_k127_7080624_4 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 607.0
PYH2_k127_7080624_5 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 525.0
PYH2_k127_7080624_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 530.0
PYH2_k127_7080624_7 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 488.0
PYH2_k127_7080624_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 461.0
PYH2_k127_7080624_9 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 443.0
PYH2_k127_70947_0 PFAM NHL repeat containing protein - - - 3.007e-295 938.0
PYH2_k127_70947_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 350.0
PYH2_k127_70947_2 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 321.0
PYH2_k127_70947_3 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006997 287.0
PYH2_k127_70947_4 CBS domain - - - 0.000000000000000000000000000000000000001141 151.0
PYH2_k127_70947_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000005364 154.0
PYH2_k127_70947_6 ABC-2 family transporter protein K01992 - - 0.0000000000002899 82.0
PYH2_k127_7104433_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.5e-323 999.0
PYH2_k127_7104433_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.69e-217 685.0
PYH2_k127_7104433_10 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000001605 164.0
PYH2_k127_7104433_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000001721 129.0
PYH2_k127_7104433_13 CAAX protease self-immunity K07052 - - 0.00000000000000002599 93.0
PYH2_k127_7104433_2 PFAM AAA ATPase central domain protein K07478 - - 2.019e-206 651.0
PYH2_k127_7104433_3 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 466.0
PYH2_k127_7104433_4 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 430.0
PYH2_k127_7104433_5 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 398.0
PYH2_k127_7104433_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 355.0
PYH2_k127_7104433_7 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 339.0
PYH2_k127_7104433_8 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000001347 202.0
PYH2_k127_7104433_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000002456 205.0
PYH2_k127_7111461_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 1.726e-309 957.0
PYH2_k127_7111461_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 3.246e-222 698.0
PYH2_k127_7111461_10 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 300.0
PYH2_k127_7111461_11 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
PYH2_k127_7111461_12 Aldolase/RraA K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002459 284.0
PYH2_k127_7111461_13 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000003453 236.0
PYH2_k127_7111461_14 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
PYH2_k127_7111461_16 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000005677 162.0
PYH2_k127_7111461_17 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000000000000000005814 142.0
PYH2_k127_7111461_18 PFAM Calcium calmodulin dependent protein kinase II - - - 0.00000000000000000000000000000000004407 139.0
PYH2_k127_7111461_19 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000004616 138.0
PYH2_k127_7111461_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 487.0
PYH2_k127_7111461_20 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000001258 118.0
PYH2_k127_7111461_21 Methyltransferase FkbM domain - - - 0.0000000000000000000000007426 117.0
PYH2_k127_7111461_22 Menaquinol-cytochrome c reductase K03886 - - 0.000000000000000000000005245 109.0
PYH2_k127_7111461_23 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.000000000000000000005194 96.0
PYH2_k127_7111461_24 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000003749 101.0
PYH2_k127_7111461_25 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000007198 88.0
PYH2_k127_7111461_26 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000003071 78.0
PYH2_k127_7111461_27 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000002434 80.0
PYH2_k127_7111461_28 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000005519 57.0
PYH2_k127_7111461_29 membrane-bound metal-dependent K07038 - - 0.0003618 51.0
PYH2_k127_7111461_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 451.0
PYH2_k127_7111461_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 420.0
PYH2_k127_7111461_5 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 398.0
PYH2_k127_7111461_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 376.0
PYH2_k127_7111461_7 GlcNAc-PI de-N-acetylase K16515 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 336.0
PYH2_k127_7111461_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 331.0
PYH2_k127_7111461_9 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 308.0
PYH2_k127_7133893_0 Multicopper oxidase - - - 1.164e-273 864.0
PYH2_k127_7133893_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 320.0
PYH2_k127_7133893_2 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000000000000000006194 193.0
PYH2_k127_7133893_3 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000006045 111.0
PYH2_k127_7133893_4 Glycosyl hydrolase family 92 - - - 0.0003341 44.0
PYH2_k127_7139248_0 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 309.0
PYH2_k127_7139248_1 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000005683 218.0
PYH2_k127_7139248_2 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00007796 47.0
PYH2_k127_7150052_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 327.0
PYH2_k127_7150052_1 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000004621 240.0
PYH2_k127_7150877_0 CoA-substrate-specific enzyme activase - - - 0.0 1300.0
PYH2_k127_7150877_1 PFAM glycosyl transferase, family 51 - - - 6.631e-247 777.0
PYH2_k127_7150877_2 Castor and Pollux, part of voltage-gated ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 609.0
PYH2_k127_7150877_3 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 353.0
PYH2_k127_7150877_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003208 254.0
PYH2_k127_7250230_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1284.0
PYH2_k127_7250230_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0 1245.0
PYH2_k127_7250230_10 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 528.0
PYH2_k127_7250230_11 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 493.0
PYH2_k127_7250230_12 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 468.0
PYH2_k127_7250230_13 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 449.0
PYH2_k127_7250230_14 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 437.0
PYH2_k127_7250230_15 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 435.0
PYH2_k127_7250230_16 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 374.0
PYH2_k127_7250230_17 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 366.0
PYH2_k127_7250230_18 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 361.0
PYH2_k127_7250230_19 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 316.0
PYH2_k127_7250230_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.791e-299 927.0
PYH2_k127_7250230_20 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 286.0
PYH2_k127_7250230_21 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009311 276.0
PYH2_k127_7250230_22 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
PYH2_k127_7250230_23 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000004185 265.0
PYH2_k127_7250230_24 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
PYH2_k127_7250230_25 adenosine deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000001548 242.0
PYH2_k127_7250230_26 Transcriptional regulatory protein, C terminal K02483,K18344 - - 0.000000000000000000000000000000000000000000000000000000000000000002753 233.0
PYH2_k127_7250230_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003568 234.0
PYH2_k127_7250230_28 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000008948 240.0
PYH2_k127_7250230_29 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000007068 210.0
PYH2_k127_7250230_3 cell adhesion involved in biofilm formation - - - 4.94e-290 904.0
PYH2_k127_7250230_30 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001448 213.0
PYH2_k127_7250230_31 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000006291 208.0
PYH2_k127_7250230_33 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000001173 177.0
PYH2_k127_7250230_34 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.00000000000000000000000000000000000000000746 165.0
PYH2_k127_7250230_35 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000002542 154.0
PYH2_k127_7250230_36 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000005324 159.0
PYH2_k127_7250230_37 Dam-replacing family K01155 - 3.1.21.4 0.00000000000000000000000000000000002762 139.0
PYH2_k127_7250230_38 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000004617 130.0
PYH2_k127_7250230_39 - - - - 0.0000000000000000000000000000006328 127.0
PYH2_k127_7250230_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 6.875e-256 816.0
PYH2_k127_7250230_40 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000001675 94.0
PYH2_k127_7250230_41 Methyltransferase domain protein K17462 - - 0.000000000000000003658 93.0
PYH2_k127_7250230_42 HAD-superfamily hydrolase, subfamily IA, variant K07025 - - 0.0000000000000000102 92.0
PYH2_k127_7250230_43 Acetyltransferase (GNAT) family - - - 0.00000000000000004481 92.0
PYH2_k127_7250230_44 Bacitracin ABC transporter, ATP-binding protein K01990 - - 0.000000005044 58.0
PYH2_k127_7250230_45 Dam-replacing family K01155 - 3.1.21.4 0.000000006584 59.0
PYH2_k127_7250230_5 major facilitator superfamily - - - 6.256e-204 650.0
PYH2_k127_7250230_6 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 1.591e-202 638.0
PYH2_k127_7250230_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 6.526e-194 619.0
PYH2_k127_7250230_8 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 601.0
PYH2_k127_7250230_9 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 590.0
PYH2_k127_7258751_0 Molydopterin dinucleotide binding domain - - - 2.334e-243 771.0
PYH2_k127_7258751_1 PFAM Polysulphide reductase, NrfD K00185 - - 8.577e-207 652.0
PYH2_k127_7258751_10 Caulimovirus viroplasmin K03469,K06993 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000002649 244.0
PYH2_k127_7258751_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000003224 243.0
PYH2_k127_7258751_12 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000003094 213.0
PYH2_k127_7258751_13 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000607 207.0
PYH2_k127_7258751_14 Acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000005381 201.0
PYH2_k127_7258751_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000002023 175.0
PYH2_k127_7258751_16 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000002209 180.0
PYH2_k127_7258751_17 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000087 164.0
PYH2_k127_7258751_18 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000002652 158.0
PYH2_k127_7258751_19 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000005404 164.0
PYH2_k127_7258751_2 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 600.0
PYH2_k127_7258751_20 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000000000005829 121.0
PYH2_k127_7258751_21 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K01497,K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000255 120.0
PYH2_k127_7258751_22 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000001859 106.0
PYH2_k127_7258751_23 response to heat K03668 - - 0.0000000000008764 79.0
PYH2_k127_7258751_3 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 545.0
PYH2_k127_7258751_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 421.0
PYH2_k127_7258751_5 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 374.0
PYH2_k127_7258751_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 353.0
PYH2_k127_7258751_7 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 346.0
PYH2_k127_7258751_8 Cytochrome c K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009779 281.0
PYH2_k127_7258751_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000584 253.0
PYH2_k127_7272075_0 Two component transcriptional regulator, winged helix family K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 367.0
PYH2_k127_7272075_1 Bacterial sugar transferase K19428 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001647 282.0
PYH2_k127_7272075_2 LysM domain - - - 0.00000000000000000002611 106.0
PYH2_k127_7297492_0 nuclear chromosome segregation - - - 6.178e-201 635.0
PYH2_k127_7297492_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 482.0
PYH2_k127_7297492_10 membrane protein, required for N-linked glycosylation K07151 - 2.4.99.18 0.000000000000000000000000000003093 130.0
PYH2_k127_7297492_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000001316 74.0
PYH2_k127_7297492_12 extracellular matrix structural constituent - - - 0.00000000006313 74.0
PYH2_k127_7297492_13 DNA-templated transcription, initiation K03088 - - 0.0000000001662 70.0
PYH2_k127_7297492_14 - - - - 0.0000000006981 71.0
PYH2_k127_7297492_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 434.0
PYH2_k127_7297492_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 415.0
PYH2_k127_7297492_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 346.0
PYH2_k127_7297492_5 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
PYH2_k127_7297492_6 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004666 236.0
PYH2_k127_7297492_7 PFAM phospholipase D Transphosphatidylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 245.0
PYH2_k127_7297492_8 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000919 199.0
PYH2_k127_7297492_9 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000000000002699 159.0
PYH2_k127_730865_0 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 379.0
PYH2_k127_730865_1 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 354.0
PYH2_k127_732638_0 Arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000644 265.0
PYH2_k127_732638_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000009123 168.0
PYH2_k127_7335577_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 382.0
PYH2_k127_7335577_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 322.0
PYH2_k127_7335577_2 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 314.0
PYH2_k127_7335577_3 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003229 235.0
PYH2_k127_7335577_4 metal-dependent membrane protease - - - 0.00000000000000000000000000000000000201 151.0
PYH2_k127_7335577_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000000003863 143.0
PYH2_k127_7348241_0 COGs COG3533 conserved K09955 - - 1.464e-219 699.0
PYH2_k127_7348241_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 372.0
PYH2_k127_7348241_2 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
PYH2_k127_7411118_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1109.0
PYH2_k127_7411118_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 2.649e-205 655.0
PYH2_k127_7411118_10 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 416.0
PYH2_k127_7411118_11 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 364.0
PYH2_k127_7411118_12 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 364.0
PYH2_k127_7411118_13 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 316.0
PYH2_k127_7411118_14 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 308.0
PYH2_k127_7411118_15 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 306.0
PYH2_k127_7411118_16 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006709 285.0
PYH2_k127_7411118_17 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000002783 273.0
PYH2_k127_7411118_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002867 282.0
PYH2_k127_7411118_19 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 266.0
PYH2_k127_7411118_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.731e-202 650.0
PYH2_k127_7411118_20 Galactokinase galactose-binding signature K18677,K19347 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046396,GO:0046835,GO:0047912,GO:0071704 2.7.1.44 0.00000000000000000000000000000000000000000000000000000000000000009531 237.0
PYH2_k127_7411118_21 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000002664 231.0
PYH2_k127_7411118_22 - - - - 0.00000000000000000000000000000000000000000002378 165.0
PYH2_k127_7411118_23 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000006312 119.0
PYH2_k127_7411118_24 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000005772 117.0
PYH2_k127_7411118_25 KR domain - - - 0.0000000000000000001079 97.0
PYH2_k127_7411118_26 - - - - 0.0000000000000002583 88.0
PYH2_k127_7411118_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 576.0
PYH2_k127_7411118_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 561.0
PYH2_k127_7411118_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 536.0
PYH2_k127_7411118_6 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 528.0
PYH2_k127_7411118_7 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K18005 - 1.12.1.2,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 522.0
PYH2_k127_7411118_8 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 489.0
PYH2_k127_7411118_9 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 464.0
PYH2_k127_7441896_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.536e-307 952.0
PYH2_k127_7441896_1 histidine kinase A domain protein - - - 7.756e-270 883.0
PYH2_k127_7441896_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 465.0
PYH2_k127_7441896_11 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 422.0
PYH2_k127_7441896_12 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 406.0
PYH2_k127_7441896_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 393.0
PYH2_k127_7441896_14 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 309.0
PYH2_k127_7441896_15 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
PYH2_k127_7441896_16 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 265.0
PYH2_k127_7441896_17 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
PYH2_k127_7441896_18 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000001727 229.0
PYH2_k127_7441896_19 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001403 199.0
PYH2_k127_7441896_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 6.176e-237 743.0
PYH2_k127_7441896_20 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000004581 191.0
PYH2_k127_7441896_21 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000003081 198.0
PYH2_k127_7441896_22 aspartic-type endopeptidase activity K02236,K02506,K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000005748 166.0
PYH2_k127_7441896_23 PFAM TadE family protein - - - 0.00000000000000000000000000000000000002381 162.0
PYH2_k127_7441896_25 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000000003061 108.0
PYH2_k127_7441896_26 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000004984 101.0
PYH2_k127_7441896_27 Transcriptional regulator - - - 0.0000000000000000001077 96.0
PYH2_k127_7441896_29 PFAM TadE family protein - - - 0.000000000000000121 88.0
PYH2_k127_7441896_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 1.864e-231 728.0
PYH2_k127_7441896_30 - - - - 0.00000000132 63.0
PYH2_k127_7441896_31 Iron-sulphur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000001331 55.0
PYH2_k127_7441896_32 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00003369 56.0
PYH2_k127_7441896_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.111e-210 659.0
PYH2_k127_7441896_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.084e-197 623.0
PYH2_k127_7441896_6 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 595.0
PYH2_k127_7441896_7 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 551.0
PYH2_k127_7441896_8 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 479.0
PYH2_k127_7441896_9 PFAM peptidase M4 thermolysin K08603 - 3.4.24.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 470.0
PYH2_k127_7462971_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1074.0
PYH2_k127_7462971_1 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 551.0
PYH2_k127_7462971_10 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000008786 221.0
PYH2_k127_7462971_11 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000006283 161.0
PYH2_k127_7462971_12 Acyltransferase family - - - 0.000000000000000000000000000000607 128.0
PYH2_k127_7462971_13 PFAM response regulator receiver K02282 - - 0.00000000000000000002652 96.0
PYH2_k127_7462971_14 - - - - 0.00000000000000001334 87.0
PYH2_k127_7462971_15 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000005302 79.0
PYH2_k127_7462971_16 - - - - 0.00000000007148 68.0
PYH2_k127_7462971_17 - - - - 0.000002293 52.0
PYH2_k127_7462971_18 - - - - 0.0008077 46.0
PYH2_k127_7462971_2 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 534.0
PYH2_k127_7462971_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 522.0
PYH2_k127_7462971_4 CoA-ligase K01902,K02381 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 468.0
PYH2_k127_7462971_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 363.0
PYH2_k127_7462971_6 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 289.0
PYH2_k127_7462971_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006232 249.0
PYH2_k127_7462971_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
PYH2_k127_7462971_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000008478 234.0
PYH2_k127_7490178_0 Cellulose biosynthesis protein BcsQ K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
PYH2_k127_7490178_1 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000001003 181.0
PYH2_k127_7490178_2 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000009521 117.0
PYH2_k127_7490178_4 Lysin motif - - - 0.000003104 59.0
PYH2_k127_7511272_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 376.0
PYH2_k127_7511272_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
PYH2_k127_7613764_0 PFAM sulfatase K01130 - 3.1.6.1 9.922e-320 995.0
PYH2_k127_7613764_1 LURP-one-related - - - 0.000000000000000000000000000000000000000000000006248 177.0
PYH2_k127_7613764_2 META domain K03929 - - 0.000000000000000000000000000000000003342 154.0
PYH2_k127_7613764_3 CAAX protease self-immunity K07052 - - 0.0000000000000968 81.0
PYH2_k127_761558_0 catalase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1244.0
PYH2_k127_761558_1 Histidine kinase K07646 - 2.7.13.3 3.458e-293 925.0
PYH2_k127_761558_10 Amino acid permease - - - 0.00000004617 66.0
PYH2_k127_761558_11 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0006429 45.0
PYH2_k127_761558_2 Belongs to the glycosyl hydrolase 2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 402.0
PYH2_k127_761558_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 316.0
PYH2_k127_761558_4 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 313.0
PYH2_k127_761558_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 281.0
PYH2_k127_761558_6 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000734 270.0
PYH2_k127_761558_7 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
PYH2_k127_761558_8 PFAM secretion protein HlyD family protein K02005 - - 0.000000000000000000000000000000000000000000000000000000002521 217.0
PYH2_k127_7646496_0 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0 1007.0
PYH2_k127_7646496_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.494e-255 801.0
PYH2_k127_7646496_10 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
PYH2_k127_7646496_11 lyase activity - - - 0.000000000000000000000000000000000000000000000001922 181.0
PYH2_k127_7646496_12 methyltransferase - - - 0.0000000000000000000000000000000000000000000188 170.0
PYH2_k127_7646496_13 Protein of unknown function (DUF2877) - - - 0.00000000000000000000636 104.0
PYH2_k127_7646496_14 - - - - 0.000000000000000002849 93.0
PYH2_k127_7646496_15 Protein of unknown function (DUF1116) - - - 0.0000000003857 62.0
PYH2_k127_7646496_16 acetoacetate decarboxylase K01574 - 4.1.1.4 0.000000006747 66.0
PYH2_k127_7646496_2 PFAM Alpha amylase, catalytic K01176,K01208 GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 514.0
PYH2_k127_7646496_3 Protein of unknown function (DUF1116) K02381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 430.0
PYH2_k127_7646496_4 CoA-ligase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 414.0
PYH2_k127_7646496_5 transport systems ATPase components K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 401.0
PYH2_k127_7646496_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 309.0
PYH2_k127_7646496_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007181 267.0
PYH2_k127_7646496_8 PFAM Basic membrane lipoprotein K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000001513 250.0
PYH2_k127_7646496_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000002385 248.0
PYH2_k127_7682010_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 331.0
PYH2_k127_7682010_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000009382 226.0
PYH2_k127_7682010_10 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000001004 111.0
PYH2_k127_7682010_11 peptidyl-tyrosine sulfation - - - 0.0000000000004757 82.0
PYH2_k127_7682010_12 Chromosome 6 open reading frame 106 - GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - 0.000000000001594 81.0
PYH2_k127_7682010_13 ubiquitin binding K17987 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708 - 0.000000000006345 79.0
PYH2_k127_7682010_14 cell adhesion involved in biofilm formation - - - 0.00000009991 66.0
PYH2_k127_7682010_15 Glycosyl transferase 4-like domain - - - 0.0000001301 66.0
PYH2_k127_7682010_16 COG3103 SH3 domain protein K01448 - 3.5.1.28 0.000003825 58.0
PYH2_k127_7682010_17 Transglutaminase-like superfamily - - - 0.00003593 53.0
PYH2_k127_7682010_2 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000000000000000000000000000000000002715 239.0
PYH2_k127_7682010_4 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000003937 164.0
PYH2_k127_7682010_5 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000002799 136.0
PYH2_k127_7682010_6 - - - - 0.000000000000000000000000000000004939 145.0
PYH2_k127_7682010_7 SMART Glycoside hydrolase, family 25 subgroup K07273 - - 0.000000000000000000000000000004395 132.0
PYH2_k127_7682010_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000791 133.0
PYH2_k127_7682010_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000009763 132.0
PYH2_k127_7690772_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.222e-213 683.0
PYH2_k127_7690772_1 WD40 repeats - - - 6.159e-197 666.0
PYH2_k127_7690772_10 PFAM Flavin containing amine oxidoreductase K09879 - - 0.0000000002215 70.0
PYH2_k127_7690772_11 protein secretion by the type VII secretion system - - - 0.000001271 57.0
PYH2_k127_7690772_12 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00001551 48.0
PYH2_k127_7690772_13 cytochrome K08738 - - 0.00005508 56.0
PYH2_k127_7690772_14 Mut7-C ubiquitin K03154 - - 0.000222 48.0
PYH2_k127_7690772_2 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 496.0
PYH2_k127_7690772_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 429.0
PYH2_k127_7690772_4 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000101 258.0
PYH2_k127_7690772_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000003697 235.0
PYH2_k127_7690772_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000006733 210.0
PYH2_k127_7690772_7 Ntpase (Nacht family) K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000009425 189.0
PYH2_k127_7690772_8 oxidoreductase activity K07114 - - 0.000000000000000000000000000000108 144.0
PYH2_k127_7690772_9 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.0000000000000000000000000000004404 126.0
PYH2_k127_7691839_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 4.563e-270 839.0
PYH2_k127_7691839_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 1.276e-195 619.0
PYH2_k127_7691839_10 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 372.0
PYH2_k127_7691839_11 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 376.0
PYH2_k127_7691839_12 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 375.0
PYH2_k127_7691839_13 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 357.0
PYH2_k127_7691839_14 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
PYH2_k127_7691839_15 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000671 240.0
PYH2_k127_7691839_16 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000006059 232.0
PYH2_k127_7691839_17 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000007495 217.0
PYH2_k127_7691839_18 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000194 211.0
PYH2_k127_7691839_19 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000003485 178.0
PYH2_k127_7691839_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 577.0
PYH2_k127_7691839_20 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000002212 175.0
PYH2_k127_7691839_21 - - - - 0.00000000000000000000000000000000000000000006681 175.0
PYH2_k127_7691839_22 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000004231 148.0
PYH2_k127_7691839_23 TIGRFAM primosome, DnaD subunit - - - 0.000000000000000000000000000000006789 136.0
PYH2_k127_7691839_24 PFAM CHAD domain containing protein K08296 - - 0.00000000000000000000000000000009611 136.0
PYH2_k127_7691839_25 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000004954 123.0
PYH2_k127_7691839_26 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000003951 105.0
PYH2_k127_7691839_27 GDP-mannose 4,6 dehydratase - - - 0.00000000000000002177 85.0
PYH2_k127_7691839_28 serine threonine protein kinase - - - 0.000000008143 64.0
PYH2_k127_7691839_29 - - - - 0.0000000294 63.0
PYH2_k127_7691839_3 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 542.0
PYH2_k127_7691839_30 Nucleotidyltransferase domain - - - 0.000009591 56.0
PYH2_k127_7691839_31 - - - - 0.00001302 52.0
PYH2_k127_7691839_32 ATPase (AAA - - - 0.0001477 46.0
PYH2_k127_7691839_4 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 479.0
PYH2_k127_7691839_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 399.0
PYH2_k127_7691839_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 398.0
PYH2_k127_7691839_7 TIGRFAM phosphate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 398.0
PYH2_k127_7691839_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 391.0
PYH2_k127_7691839_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 387.0
PYH2_k127_7730858_0 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 372.0
PYH2_k127_7730858_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 346.0
PYH2_k127_7730858_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.0000000000000000000000000002112 132.0
PYH2_k127_7732678_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.608e-219 709.0
PYH2_k127_7732678_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 514.0
PYH2_k127_7732678_10 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 302.0
PYH2_k127_7732678_11 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
PYH2_k127_7732678_12 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
PYH2_k127_7732678_13 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000005819 207.0
PYH2_k127_7732678_14 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000876 204.0
PYH2_k127_7732678_16 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000001207 173.0
PYH2_k127_7732678_17 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000001008 160.0
PYH2_k127_7732678_18 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000002851 162.0
PYH2_k127_7732678_19 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000001191 153.0
PYH2_k127_7732678_2 Pyruvate phosphate dikinase, PEP pyruvate binding K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 505.0
PYH2_k127_7732678_20 Major facilitator Superfamily - - - 0.000000000000000000000000000000000663 146.0
PYH2_k127_7732678_21 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000273 82.0
PYH2_k127_7732678_22 Psort location CytoplasmicMembrane, score - - - 0.00000000001787 73.0
PYH2_k127_7732678_23 regulatory protein, FmdB family - - - 0.000000001074 62.0
PYH2_k127_7732678_24 Phosphate acyltransferases K00655 - 2.3.1.51 0.00006085 53.0
PYH2_k127_7732678_25 PFAM S-layer domain protein - - - 0.00008264 50.0
PYH2_k127_7732678_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 491.0
PYH2_k127_7732678_4 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 435.0
PYH2_k127_7732678_5 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 405.0
PYH2_k127_7732678_6 PFAM magnesium chelatase ChlI subunit K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 396.0
PYH2_k127_7732678_7 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 356.0
PYH2_k127_7732678_8 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 347.0
PYH2_k127_7732678_9 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 316.0
PYH2_k127_7740894_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 394.0
PYH2_k127_7740894_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 327.0
PYH2_k127_7740894_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003775 177.0
PYH2_k127_7740894_3 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000002352 184.0
PYH2_k127_7740894_4 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.000000000001202 73.0
PYH2_k127_7740894_5 Transposase DDE domain - - - 0.0000001026 58.0
PYH2_k127_7740894_6 SPTR Transposase, IS4 family protein - - - 0.0000005471 52.0
PYH2_k127_7740894_7 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0003324 50.0
PYH2_k127_7850703_0 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 289.0
PYH2_k127_7850703_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001669 179.0
PYH2_k127_7850703_2 RNA-binding - - - 0.000000000000002489 79.0
PYH2_k127_7916961_0 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 325.0
PYH2_k127_7916961_1 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000006218 211.0
PYH2_k127_7916961_2 PFAM PEBP family protein K06910 - - 0.00000000000000000000000000000000000000002466 165.0
PYH2_k127_7916961_3 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.000000000000000000000000000000000000000919 153.0
PYH2_k127_7918834_0 Required for chromosome condensation and partitioning K03529 - - 2.404e-314 1001.0
PYH2_k127_7918834_1 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
PYH2_k127_7918834_10 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000000000000000000005074 194.0
PYH2_k127_7918834_11 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000001682 145.0
PYH2_k127_7918834_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000004074 129.0
PYH2_k127_7918834_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000002556 121.0
PYH2_k127_7918834_14 lactoylglutathione lyase activity - - - 0.000000000000000000000007601 104.0
PYH2_k127_7918834_15 self proteolysis - - - 0.000000001848 71.0
PYH2_k127_7918834_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00006689 49.0
PYH2_k127_7918834_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 436.0
PYH2_k127_7918834_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 384.0
PYH2_k127_7918834_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 301.0
PYH2_k127_7918834_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002617 286.0
PYH2_k127_7918834_6 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001837 258.0
PYH2_k127_7918834_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000002626 222.0
PYH2_k127_7918834_8 channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000001898 215.0
PYH2_k127_7918834_9 Membrane protein involved in D-alanine export K03739,K19294 - - 0.0000000000000000000000000000000000000000000000000000006995 211.0
PYH2_k127_7936962_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 565.0
PYH2_k127_7936962_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004667 288.0
PYH2_k127_7952011_0 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 439.0
PYH2_k127_7952011_1 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 365.0
PYH2_k127_7952011_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000003038 144.0
PYH2_k127_795348_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 390.0
PYH2_k127_795348_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 317.0
PYH2_k127_795348_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000004248 80.0
PYH2_k127_795911_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.235e-296 931.0
PYH2_k127_795911_1 Serine threonine protein kinase K12132 - 2.7.11.1 9.829e-288 895.0
PYH2_k127_795911_10 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 310.0
PYH2_k127_795911_11 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
PYH2_k127_795911_12 SMP-30/Gluconolaconase/LRE-like region K14274 GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 295.0
PYH2_k127_795911_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005095 258.0
PYH2_k127_795911_14 DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001128 251.0
PYH2_k127_795911_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000002967 236.0
PYH2_k127_795911_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000001456 228.0
PYH2_k127_795911_17 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000001874 214.0
PYH2_k127_795911_19 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000009656 199.0
PYH2_k127_795911_2 PFAM Dak phosphatase K07030 - - 1.683e-217 689.0
PYH2_k127_795911_20 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000006055 194.0
PYH2_k127_795911_21 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000004832 188.0
PYH2_k127_795911_22 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000004989 182.0
PYH2_k127_795911_23 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000000000000000000000000000005403 177.0
PYH2_k127_795911_24 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000000000000000000000007418 165.0
PYH2_k127_795911_25 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000001007 159.0
PYH2_k127_795911_26 - - - - 0.00000000000000000000000000000000000000001054 156.0
PYH2_k127_795911_27 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000001658 164.0
PYH2_k127_795911_28 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000002065 155.0
PYH2_k127_795911_29 TIGRFAM lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000000000000000000001114 154.0
PYH2_k127_795911_3 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 532.0
PYH2_k127_795911_31 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000002167 122.0
PYH2_k127_795911_32 - - - - 0.000000000000000000000000001081 123.0
PYH2_k127_795911_33 - - - - 0.0000000000000000000000000341 109.0
PYH2_k127_795911_34 protein conserved in bacteria - - - 0.000000000000000000000001825 107.0
PYH2_k127_795911_35 ribosomal protein L28 K02902 - - 0.0000000000000000000004288 96.0
PYH2_k127_795911_36 - - - - 0.0000000000000244 78.0
PYH2_k127_795911_37 Major facilitator Superfamily - - - 0.00000000000002822 74.0
PYH2_k127_795911_38 Protein of unknown function (DUF1294) - - - 0.00000000006573 68.0
PYH2_k127_795911_39 Regulatory protein, FmdB family - - - 0.00001072 49.0
PYH2_k127_795911_4 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 405.0
PYH2_k127_795911_5 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 406.0
PYH2_k127_795911_6 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 380.0
PYH2_k127_795911_7 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
PYH2_k127_795911_8 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 336.0
PYH2_k127_795911_9 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 329.0
PYH2_k127_8093281_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 321.0
PYH2_k127_8093281_1 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000004677 166.0
PYH2_k127_8093281_2 PFAM transglutaminase domain protein - - - 0.000000000000006327 86.0
PYH2_k127_8097887_0 energy transducer activity K03531,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 321.0
PYH2_k127_8097887_1 nitronate monooxygenase activity K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004584 267.0
PYH2_k127_8097887_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000002637 132.0
PYH2_k127_8158977_0 MFS/sugar transport protein K03292 - - 9.998e-202 636.0
PYH2_k127_8158977_1 PFAM aminotransferase class V K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 606.0
PYH2_k127_8158977_10 CAAX protease self-immunity - - - 0.000000000000000000000000000000001278 142.0
PYH2_k127_8158977_11 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000001401 128.0
PYH2_k127_8158977_12 CAAX protease self-immunity K07052 - - 0.000000000000000000000001763 116.0
PYH2_k127_8158977_13 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000002326 103.0
PYH2_k127_8158977_14 TIM barrel - - - 0.0000000000000000000003444 97.0
PYH2_k127_8158977_15 PFAM Abortive infection protein - - - 0.0000000000000000008157 98.0
PYH2_k127_8158977_16 - - - - 0.00000000000000004649 83.0
PYH2_k127_8158977_17 - - - - 0.00000000000001805 84.0
PYH2_k127_8158977_18 CAAX protease self-immunity K07052 - - 0.000003635 58.0
PYH2_k127_8158977_2 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 584.0
PYH2_k127_8158977_3 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 505.0
PYH2_k127_8158977_4 Alanine racemase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 355.0
PYH2_k127_8158977_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 330.0
PYH2_k127_8158977_6 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000000000000000000001847 214.0
PYH2_k127_8158977_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000006655 217.0
PYH2_k127_8158977_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000003525 153.0
PYH2_k127_8158977_9 Methyltransferase type 11 - - - 0.0000000000000000000000000000000003779 141.0
PYH2_k127_8181996_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 610.0
PYH2_k127_8181996_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 353.0
PYH2_k127_8181996_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000002594 197.0
PYH2_k127_8195347_0 Transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 561.0
PYH2_k127_8195347_1 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 440.0
PYH2_k127_8195347_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000002251 55.0
PYH2_k127_8195347_11 CHAT domain - - - 0.0001 54.0
PYH2_k127_8195347_12 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0002681 51.0
PYH2_k127_8195347_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 408.0
PYH2_k127_8195347_3 transcription factor binding K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000028 256.0
PYH2_k127_8195347_4 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000003053 240.0
PYH2_k127_8195347_5 - - - - 0.000000000000000000000000000000000000000005307 164.0
PYH2_k127_8195347_6 histone H2A K63-linked ubiquitination K01768 - 4.6.1.1 0.00000000000000000004667 102.0
PYH2_k127_8195347_7 Family of unknown function (DUF5317) - - - 0.00000000004156 71.0
PYH2_k127_8195347_8 - - - - 0.00000002977 59.0
PYH2_k127_8220995_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.068e-229 723.0
PYH2_k127_8220995_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 283.0
PYH2_k127_8220995_2 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008755 275.0
PYH2_k127_8220995_3 Histidine kinase K07642,K10681 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002437 237.0
PYH2_k127_8220995_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000003387 134.0
PYH2_k127_8220995_5 Receptor family ligand binding region K01999 - - 0.0000000002353 61.0
PYH2_k127_8251266_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 386.0
PYH2_k127_8251266_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 315.0
PYH2_k127_8251266_2 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 299.0
PYH2_k127_8251266_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000003194 226.0
PYH2_k127_8251266_4 quinone binding - - - 0.0000000000000000000002271 101.0
PYH2_k127_8256965_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1387.0
PYH2_k127_8256965_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 434.0
PYH2_k127_8256965_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 352.0
PYH2_k127_8256965_3 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000005895 87.0
PYH2_k127_8320301_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000007716 189.0
PYH2_k127_8320301_1 SnoaL-like polyketide cyclase - - - 0.000000000003905 72.0
PYH2_k127_8320301_2 Ribosomal protein L7/L12 C-terminal domain - - - 0.000006298 53.0
PYH2_k127_8382061_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1092.0
PYH2_k127_8382061_1 PFAM TPR repeat-containing protein - - - 3.378e-206 666.0
PYH2_k127_8382061_10 proteolysis K21140 - 3.13.1.6 0.000000000000000000000006339 106.0
PYH2_k127_8382061_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.015e-195 622.0
PYH2_k127_8382061_3 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 557.0
PYH2_k127_8382061_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 405.0
PYH2_k127_8382061_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 372.0
PYH2_k127_8382061_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000194 258.0
PYH2_k127_8382061_9 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000007206 183.0
PYH2_k127_8387559_0 MacB-like periplasmic core domain K02004 - - 1.304e-260 829.0
PYH2_k127_8387559_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 2.648e-241 751.0
PYH2_k127_8387559_10 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 376.0
PYH2_k127_8387559_11 COG COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 372.0
PYH2_k127_8387559_12 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 359.0
PYH2_k127_8387559_13 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 352.0
PYH2_k127_8387559_14 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 349.0
PYH2_k127_8387559_15 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 325.0
PYH2_k127_8387559_16 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 320.0
PYH2_k127_8387559_17 ABC-type sugar transport system, permease component K02026,K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 306.0
PYH2_k127_8387559_18 carbohydrate transport K02027,K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 312.0
PYH2_k127_8387559_19 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 309.0
PYH2_k127_8387559_2 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 2.896e-207 676.0
PYH2_k127_8387559_20 alcohol dehydrogenase K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 305.0
PYH2_k127_8387559_21 ABC-type sugar transport system, permease component K02026,K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 295.0
PYH2_k127_8387559_22 Domain of unknown function (DUF4432) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 295.0
PYH2_k127_8387559_23 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 293.0
PYH2_k127_8387559_24 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
PYH2_k127_8387559_25 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 296.0
PYH2_k127_8387559_26 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001434 300.0
PYH2_k127_8387559_27 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001114 276.0
PYH2_k127_8387559_28 Binding-protein-dependent transport system inner membrane component K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
PYH2_k127_8387559_29 Binding-protein-dependent transport system inner membrane component K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004755 275.0
PYH2_k127_8387559_3 xylulokinase activity K00854 - 2.7.1.17 1.207e-199 634.0
PYH2_k127_8387559_30 PFAM cyclase family protein K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002512 263.0
PYH2_k127_8387559_31 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003817 268.0
PYH2_k127_8387559_32 Psort location CytoplasmicMembrane, score 10.00 K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
PYH2_k127_8387559_33 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003258 256.0
PYH2_k127_8387559_34 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000001652 244.0
PYH2_k127_8387559_35 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000003865 239.0
PYH2_k127_8387559_36 cobalamin binding K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000005311 229.0
PYH2_k127_8387559_37 DeoR C terminal sensor domain K02081 - - 0.00000000000000000000000000000000000000000000000000000000000000007134 231.0
PYH2_k127_8387559_38 SIS domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000337 233.0
PYH2_k127_8387559_39 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000001673 217.0
PYH2_k127_8387559_4 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 551.0
PYH2_k127_8387559_40 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000001127 209.0
PYH2_k127_8387559_41 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000004733 203.0
PYH2_k127_8387559_42 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001224 196.0
PYH2_k127_8387559_43 Domain of unknown function (DUF1768) K09935 - - 0.00000000000000000000000000000000000000000000000000002237 192.0
PYH2_k127_8387559_44 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000004656 201.0
PYH2_k127_8387559_45 - - - - 0.000000000000000000000000000000000000000000000005337 181.0
PYH2_k127_8387559_46 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000002187 178.0
PYH2_k127_8387559_47 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000177 164.0
PYH2_k127_8387559_48 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000004485 158.0
PYH2_k127_8387559_49 Transcriptional regulator IclR K13641 - - 0.00000000000000000000000000000000000000005087 161.0
PYH2_k127_8387559_5 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 466.0
PYH2_k127_8387559_50 Aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000001532 161.0
PYH2_k127_8387559_51 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000001606 163.0
PYH2_k127_8387559_52 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000002439 151.0
PYH2_k127_8387559_54 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000009192 141.0
PYH2_k127_8387559_56 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000002714 107.0
PYH2_k127_8387559_57 - - - - 0.000000000000000000000001511 109.0
PYH2_k127_8387559_58 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source - - - 0.00000000000000000004338 96.0
PYH2_k127_8387559_59 Formate hydrogenlyase K12136,K15827 - - 0.000000000000002388 89.0
PYH2_k127_8387559_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 451.0
PYH2_k127_8387559_61 - - - - 0.000000000000006868 78.0
PYH2_k127_8387559_62 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000002328 81.0
PYH2_k127_8387559_63 Cobalt transport protein K16785 - - 0.000000000006591 74.0
PYH2_k127_8387559_64 Domain of unknown function (DUF4143) K07133 - - 0.00000000001838 64.0
PYH2_k127_8387559_65 - - - - 0.0000000004282 69.0
PYH2_k127_8387559_66 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000003203 61.0
PYH2_k127_8387559_67 - - - - 0.0000001244 57.0
PYH2_k127_8387559_68 Amidohydrolase K07045 - - 0.0000001449 62.0
PYH2_k127_8387559_7 ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 460.0
PYH2_k127_8387559_70 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000001225 60.0
PYH2_k127_8387559_71 FtsX-like permease family K02004 - - 0.000002058 59.0
PYH2_k127_8387559_72 FtsX-like permease family K02004 - - 0.000002553 59.0
PYH2_k127_8387559_73 PFAM Metallo-beta-lactamase superfamily - - - 0.00007814 47.0
PYH2_k127_8387559_74 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00009889 48.0
PYH2_k127_8387559_75 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.0002387 52.0
PYH2_k127_8387559_8 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 449.0
PYH2_k127_8387559_9 Psort location Cytoplasmic, score 8.87 K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 410.0
PYH2_k127_8443560_0 histidine kinase A domain protein - - - 0.0 1260.0
PYH2_k127_8443560_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 6.55e-237 739.0
PYH2_k127_8443560_10 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 314.0
PYH2_k127_8443560_11 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 307.0
PYH2_k127_8443560_12 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 303.0
PYH2_k127_8443560_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 300.0
PYH2_k127_8443560_14 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 294.0
PYH2_k127_8443560_15 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000005182 292.0
PYH2_k127_8443560_16 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000005184 267.0
PYH2_k127_8443560_17 Protein of unknown function (DUF1349) K09702 - - 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
PYH2_k127_8443560_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009972 238.0
PYH2_k127_8443560_19 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
PYH2_k127_8443560_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.065e-227 713.0
PYH2_k127_8443560_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000002074 219.0
PYH2_k127_8443560_21 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000007393 221.0
PYH2_k127_8443560_22 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001083 209.0
PYH2_k127_8443560_23 membrane - - - 0.000000000000000000000000000000000000000000000000000007063 199.0
PYH2_k127_8443560_24 enterobactin catabolic process K07214 - - 0.00000000000000000000000000000000000000000000000000001566 201.0
PYH2_k127_8443560_25 - - - - 0.00000000000000000000000000000000000000000000000001049 191.0
PYH2_k127_8443560_26 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000002766 180.0
PYH2_k127_8443560_27 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.000000000000000000000000000000000000000000000008442 178.0
PYH2_k127_8443560_28 integral membrane protein - - - 0.0000000000000000000000000000000000000000000006705 181.0
PYH2_k127_8443560_29 - - - - 0.000000000000000000000000000000000002141 146.0
PYH2_k127_8443560_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.417e-201 638.0
PYH2_k127_8443560_30 - - - - 0.000000000000000000000000000000000002347 145.0
PYH2_k127_8443560_31 - - - - 0.0000000000000000000000000000000009417 139.0
PYH2_k127_8443560_32 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.0000000000000000000000000000004484 131.0
PYH2_k127_8443560_33 Transcriptional regulator - - - 0.000000000000000000000000000004446 122.0
PYH2_k127_8443560_34 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000001276 107.0
PYH2_k127_8443560_35 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000002563 98.0
PYH2_k127_8443560_36 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000008215 92.0
PYH2_k127_8443560_38 COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit - - - 0.000000000000000007262 85.0
PYH2_k127_8443560_39 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000006607 81.0
PYH2_k127_8443560_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 474.0
PYH2_k127_8443560_40 PFAM conserved - - - 0.00000000002002 70.0
PYH2_k127_8443560_43 Nuclease-related domain - - - 0.0007277 51.0
PYH2_k127_8443560_5 nitrite transmembrane transporter activity K02532 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 439.0
PYH2_k127_8443560_6 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 437.0
PYH2_k127_8443560_7 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 376.0
PYH2_k127_8443560_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 324.0
PYH2_k127_8443560_9 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 321.0
PYH2_k127_8489416_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 1.319e-242 774.0
PYH2_k127_8489416_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 480.0
PYH2_k127_8489416_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001669 250.0
PYH2_k127_8489416_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000637 162.0
PYH2_k127_8491144_0 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 1.684e-201 638.0
PYH2_k127_8491144_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004976 236.0
PYH2_k127_8507911_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 363.0
PYH2_k127_8507911_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000006586 66.0
PYH2_k127_8535968_0 Alpha-Mannosidase K01191,K15524 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 3.2.1.170,3.2.1.24 0.0 1022.0
PYH2_k127_8535968_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 3.789e-254 812.0
PYH2_k127_8535968_10 PFAM Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 462.0
PYH2_k127_8535968_11 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 446.0
PYH2_k127_8535968_12 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 428.0
PYH2_k127_8535968_13 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 427.0
PYH2_k127_8535968_14 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 375.0
PYH2_k127_8535968_15 CpXC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 380.0
PYH2_k127_8535968_16 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
PYH2_k127_8535968_17 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 355.0
PYH2_k127_8535968_18 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 354.0
PYH2_k127_8535968_19 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 340.0
PYH2_k127_8535968_2 SMART AAA ATPase - - - 3.451e-226 706.0
PYH2_k127_8535968_20 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 334.0
PYH2_k127_8535968_21 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
PYH2_k127_8535968_22 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 331.0
PYH2_k127_8535968_23 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 311.0
PYH2_k127_8535968_24 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009389 279.0
PYH2_k127_8535968_25 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001882 278.0
PYH2_k127_8535968_26 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001002 259.0
PYH2_k127_8535968_27 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000001099 259.0
PYH2_k127_8535968_28 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000006749 240.0
PYH2_k127_8535968_29 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006727 220.0
PYH2_k127_8535968_3 His Kinase A (phosphoacceptor) domain - - - 2.554e-207 655.0
PYH2_k127_8535968_30 - - - - 0.00000000000000000000000000000000000000000000000000000000004041 213.0
PYH2_k127_8535968_31 Redoxin - - - 0.000000000000000000000000000000009139 130.0
PYH2_k127_8535968_32 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000009631 123.0
PYH2_k127_8535968_4 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 2.021e-203 643.0
PYH2_k127_8535968_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 601.0
PYH2_k127_8535968_6 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 583.0
PYH2_k127_8535968_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 507.0
PYH2_k127_8535968_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 510.0
PYH2_k127_8535968_9 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 456.0
PYH2_k127_8572391_0 Alpha amylase, catalytic domain - - - 0.0 1095.0
PYH2_k127_8572391_1 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 445.0
PYH2_k127_8572391_10 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007338 278.0
PYH2_k127_8572391_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001636 260.0
PYH2_k127_8572391_12 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000001292 267.0
PYH2_k127_8572391_13 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000007274 242.0
PYH2_k127_8572391_14 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000000003022 219.0
PYH2_k127_8572391_16 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000004799 215.0
PYH2_k127_8572391_17 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000001343 214.0
PYH2_k127_8572391_18 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000004451 181.0
PYH2_k127_8572391_19 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000006809 174.0
PYH2_k127_8572391_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 424.0
PYH2_k127_8572391_20 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000007431 169.0
PYH2_k127_8572391_21 Haem-binding domain - - - 0.000000000000000000000000000000000000004397 150.0
PYH2_k127_8572391_22 cytochrome complex assembly K02200,K04018 - - 0.00000000000000000000000000000000000001766 166.0
PYH2_k127_8572391_23 AAA domain - - - 0.000000000000000000000000000000001612 136.0
PYH2_k127_8572391_24 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000002366 128.0
PYH2_k127_8572391_25 Wd40 repeat-containing protein K12132 - 2.7.11.1 0.000000000000000000000000000008167 132.0
PYH2_k127_8572391_26 Domain of unknown function (DUF4342) - - - 0.00000000000000000002779 93.0
PYH2_k127_8572391_27 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001136 88.0
PYH2_k127_8572391_28 - - - - 0.00000000000000000118 87.0
PYH2_k127_8572391_29 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.000000000000000003337 95.0
PYH2_k127_8572391_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 409.0
PYH2_k127_8572391_30 Glycosyltransferase family 87 - - - 0.000000000000278 82.0
PYH2_k127_8572391_31 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000001178 71.0
PYH2_k127_8572391_32 - - - - 0.000000000128 69.0
PYH2_k127_8572391_33 Domain of unknown function (DUF4129) - - - 0.0000001129 64.0
PYH2_k127_8572391_34 phosphotransferase activity, carboxyl group as acceptor - - - 0.0000005735 60.0
PYH2_k127_8572391_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 403.0
PYH2_k127_8572391_5 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 406.0
PYH2_k127_8572391_6 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 372.0
PYH2_k127_8572391_7 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 329.0
PYH2_k127_8572391_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 322.0
PYH2_k127_8572391_9 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002512 284.0
PYH2_k127_8658271_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 317.0
PYH2_k127_8658271_1 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 297.0
PYH2_k127_8658271_2 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000000000000000000792 209.0
PYH2_k127_8658271_3 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000003934 150.0
PYH2_k127_8658271_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000001383 95.0
PYH2_k127_8733325_0 PFAM ABC transporter related K10112 - - 8.17e-198 621.0
PYH2_k127_8733325_1 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000000000000000000000000000000000000258 213.0
PYH2_k127_8733325_2 ABC-type sugar transport system, permease component K10119 - - 0.0000000000000000001176 89.0
PYH2_k127_8755494_0 response regulator, receiver K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 451.0
PYH2_k127_8755494_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 350.0
PYH2_k127_8755494_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005703 270.0
PYH2_k127_8812176_0 acyl-CoA dehydrogenase - - - 1.103e-281 873.0
PYH2_k127_8812176_1 (ABC) transporter K06147 - - 3.361e-244 771.0
PYH2_k127_8812176_10 transporter K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 423.0
PYH2_k127_8812176_11 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 392.0
PYH2_k127_8812176_12 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 351.0
PYH2_k127_8812176_13 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 341.0
PYH2_k127_8812176_14 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 359.0
PYH2_k127_8812176_15 Protein of unknown function (DUF1152) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 345.0
PYH2_k127_8812176_16 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 325.0
PYH2_k127_8812176_17 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 321.0
PYH2_k127_8812176_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 314.0
PYH2_k127_8812176_19 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 308.0
PYH2_k127_8812176_2 PFAM ABC transporter transmembrane region K06147 - - 3.731e-239 758.0
PYH2_k127_8812176_20 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 289.0
PYH2_k127_8812176_21 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007659 276.0
PYH2_k127_8812176_22 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000089 269.0
PYH2_k127_8812176_23 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000001813 263.0
PYH2_k127_8812176_24 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000649 251.0
PYH2_k127_8812176_25 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000001055 251.0
PYH2_k127_8812176_26 PFAM Diacylglycerol kinase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001744 241.0
PYH2_k127_8812176_27 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000005424 217.0
PYH2_k127_8812176_28 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000001228 218.0
PYH2_k127_8812176_29 - - - - 0.0000000000000000000000000000000000000000000000000000001523 206.0
PYH2_k127_8812176_3 Belongs to the thiolase family K00626 - 2.3.1.9 2.947e-220 691.0
PYH2_k127_8812176_30 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001922 194.0
PYH2_k127_8812176_31 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000006841 193.0
PYH2_k127_8812176_32 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000003988 179.0
PYH2_k127_8812176_33 PFAM NLI interacting factor - - - 0.000000000000000000000000000000000000000000000001197 182.0
PYH2_k127_8812176_34 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000642 179.0
PYH2_k127_8812176_35 Macro domain - - - 0.0000000000000000000000000000000000000000000004922 171.0
PYH2_k127_8812176_36 diadenosine tetraphosphate K02503 - - 0.000000000000000000000000000000000000000000002102 173.0
PYH2_k127_8812176_37 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000002282 164.0
PYH2_k127_8812176_38 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000000008531 159.0
PYH2_k127_8812176_39 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000003289 160.0
PYH2_k127_8812176_4 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 7.475e-206 667.0
PYH2_k127_8812176_40 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000006157 141.0
PYH2_k127_8812176_44 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000009877 108.0
PYH2_k127_8812176_45 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000002508 98.0
PYH2_k127_8812176_46 - - - - 0.000000000000000000001821 99.0
PYH2_k127_8812176_47 DNA-binding transcription factor activity - - - 0.0000000000000000000789 94.0
PYH2_k127_8812176_48 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000005086 87.0
PYH2_k127_8812176_49 F420H(2)-dependent quinone reductase - - - 0.0000000000000001149 87.0
PYH2_k127_8812176_5 - K07138 - - 1.685e-202 636.0
PYH2_k127_8812176_50 - - - - 0.000000000000002713 82.0
PYH2_k127_8812176_51 domain protein K01186 - 3.2.1.18 0.00000000000002437 81.0
PYH2_k127_8812176_52 self proteolysis - - - 0.0000000004163 70.0
PYH2_k127_8812176_55 Tetratricopeptide TPR_2 repeat protein - - - 0.00003278 52.0
PYH2_k127_8812176_56 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00003901 51.0
PYH2_k127_8812176_57 Alpha beta hydrolase fold - - - 0.00009894 49.0
PYH2_k127_8812176_6 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 591.0
PYH2_k127_8812176_7 COG0520 Selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 567.0
PYH2_k127_8812176_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 421.0
PYH2_k127_8812176_9 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 419.0
PYH2_k127_8823011_0 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 624.0
PYH2_k127_8823011_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 615.0
PYH2_k127_8823011_10 NUDIX domain - - - 0.000000000000000000000000008354 116.0
PYH2_k127_8823011_12 Protein of unknown function (DUF3467) - - - 0.00000000000001424 80.0
PYH2_k127_8823011_13 - - - - 0.00007093 47.0
PYH2_k127_8823011_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 408.0
PYH2_k127_8823011_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 359.0
PYH2_k127_8823011_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 340.0
PYH2_k127_8823011_5 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002189 265.0
PYH2_k127_8823011_6 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003544 264.0
PYH2_k127_8823011_7 Protein of unknown function (DUF3090) - - - 0.000000000000000000000000000000000000000000000000000000000000000007679 228.0
PYH2_k127_8823011_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000004594 184.0
PYH2_k127_8823011_9 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000000000004112 132.0
PYH2_k127_8880267_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 302.0
PYH2_k127_8880267_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000001397 176.0
PYH2_k127_8893394_0 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000007294 215.0
PYH2_k127_8893394_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000002426 203.0
PYH2_k127_8893394_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0003061 43.0
PYH2_k127_8955905_0 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000001676 137.0
PYH2_k127_8955905_1 metal-dependent membrane protease K07052 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564 - 0.00000000000000000000000000007384 126.0
PYH2_k127_8991930_0 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001013 254.0
PYH2_k127_8991930_1 Domain of unknown function (DUF4037) - - - 0.000000000000000000000000000000000000000000000000000000000000000000156 235.0
PYH2_k127_8991930_2 signal transduction histidine kinase K11623 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000003346 217.0
PYH2_k127_9047284_0 - - - - 0.000000000000000000000000000000000000000000000000004184 198.0
PYH2_k127_9047284_1 LysM domain K12204 - - 0.0000006626 63.0
PYH2_k127_9047284_2 Protein of unknown function (DUF1349) - - - 0.0001679 55.0
PYH2_k127_9081752_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000001103 203.0
PYH2_k127_9081752_1 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000002337 181.0
PYH2_k127_9081752_2 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000002877 138.0
PYH2_k127_9089095_0 ABC transporter transmembrane region K12541 - - 6.452e-206 650.0
PYH2_k127_9089095_1 type I secretion membrane fusion protein, HlyD family K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 480.0
PYH2_k127_9089095_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000003275 151.0
PYH2_k127_9089095_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000004659 98.0
PYH2_k127_9089095_4 tryptophan synthase subunit beta - - - 0.0000000000000000004419 91.0
PYH2_k127_9135758_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1050.0
PYH2_k127_9135758_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 1.6e-285 894.0
PYH2_k127_9135758_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 350.0
PYH2_k127_9135758_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 343.0
PYH2_k127_9135758_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 324.0
PYH2_k127_9135758_13 TIGRFAM MazG family protein K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 325.0
PYH2_k127_9135758_14 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 313.0
PYH2_k127_9135758_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 283.0
PYH2_k127_9135758_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003868 278.0
PYH2_k127_9135758_17 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
PYH2_k127_9135758_18 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
PYH2_k127_9135758_19 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 271.0
PYH2_k127_9135758_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 542.0
PYH2_k127_9135758_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 252.0
PYH2_k127_9135758_21 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002724 256.0
PYH2_k127_9135758_22 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
PYH2_k127_9135758_23 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004809 230.0
PYH2_k127_9135758_24 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000004659 228.0
PYH2_k127_9135758_25 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000006747 226.0
PYH2_k127_9135758_26 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000004249 215.0
PYH2_k127_9135758_27 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000004415 228.0
PYH2_k127_9135758_28 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002268 208.0
PYH2_k127_9135758_29 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000001017 206.0
PYH2_k127_9135758_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 520.0
PYH2_k127_9135758_30 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000002361 194.0
PYH2_k127_9135758_31 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003519 190.0
PYH2_k127_9135758_32 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000001926 190.0
PYH2_k127_9135758_33 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000000000000000000000000000000000000000000001475 209.0
PYH2_k127_9135758_34 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001941 183.0
PYH2_k127_9135758_35 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000005106 170.0
PYH2_k127_9135758_36 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000003729 157.0
PYH2_k127_9135758_37 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000006137 154.0
PYH2_k127_9135758_38 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000008935 154.0
PYH2_k127_9135758_39 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002969 146.0
PYH2_k127_9135758_4 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 533.0
PYH2_k127_9135758_40 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000003752 144.0
PYH2_k127_9135758_41 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000007644 145.0
PYH2_k127_9135758_42 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000007929 131.0
PYH2_k127_9135758_43 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000006092 127.0
PYH2_k127_9135758_44 PFAM extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000005678 137.0
PYH2_k127_9135758_45 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000004402 116.0
PYH2_k127_9135758_46 PFAM alpha beta hydrolase fold - - - 0.0000000000000000002742 98.0
PYH2_k127_9135758_47 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000006017 102.0
PYH2_k127_9135758_48 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000006926 77.0
PYH2_k127_9135758_49 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001798 76.0
PYH2_k127_9135758_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 460.0
PYH2_k127_9135758_50 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002707 79.0
PYH2_k127_9135758_51 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000002306 68.0
PYH2_k127_9135758_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 471.0
PYH2_k127_9135758_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 443.0
PYH2_k127_9135758_8 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 421.0
PYH2_k127_9135758_9 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
PYH2_k127_9207780_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 367.0
PYH2_k127_9207780_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002579 289.0
PYH2_k127_9207780_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 278.0
PYH2_k127_9207780_3 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001134 258.0
PYH2_k127_9207780_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
PYH2_k127_9320430_0 PFAM VanW family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 615.0
PYH2_k127_9320430_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 511.0
PYH2_k127_9320430_2 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 387.0
PYH2_k127_9320430_3 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 316.0
PYH2_k127_9320430_4 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000188 143.0
PYH2_k127_9320430_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000003791 117.0
PYH2_k127_9320430_6 AAA-like domain - - - 0.000000000009175 76.0
PYH2_k127_9320430_7 PBS lyase HEAT-like repeat - - - 0.0002641 51.0
PYH2_k127_968865_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 559.0
PYH2_k127_968865_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 342.0
PYH2_k127_968865_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 344.0
PYH2_k127_968865_3 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 261.0
PYH2_k127_968865_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
PYH2_k127_968865_6 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000001271 168.0
PYH2_k127_968865_7 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000486 171.0
PYH2_k127_968865_8 - - - - 0.00009064 54.0