logo

Overview

ID MAG03199
Name PYH2_bin.55
Sample SMP0074
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus Methanoregula
Species
Assembly information
Completeness (%) 52.22
Contamination (%) 0.18
GC content (%) 47.0
N50 (bp) 3,956
Genome size (bp) 947,532

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1062

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1012841_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 5.747e-206 649.0
PYH2_k127_1012841_1 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 367.0
PYH2_k127_1012841_2 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 286.0
PYH2_k127_1012841_3 TIR domain - - - 0.0000000000000000000000000000000000000000002381 165.0
PYH2_k127_1012841_4 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000000000000000000000000001064 119.0
PYH2_k127_1020936_0 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 372.0
PYH2_k127_1020936_1 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 293.0
PYH2_k127_1020936_2 Helix-turn-helix domain protein K03627 - - 0.000000000000000000000000000000000000000000000000000000000000000002079 230.0
PYH2_k127_1020936_3 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000003806 155.0
PYH2_k127_1133232_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 6.338e-212 661.0
PYH2_k127_1133232_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 610.0
PYH2_k127_1133232_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 390.0
PYH2_k127_1133232_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 298.0
PYH2_k127_1133232_4 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 297.0
PYH2_k127_1133232_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000001549 186.0
PYH2_k127_1133232_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000001215 182.0
PYH2_k127_1133232_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000000005691 102.0
PYH2_k127_1133232_8 - - - - 0.0000000000000009201 78.0
PYH2_k127_1161199_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 1.966e-206 645.0
PYH2_k127_1161199_1 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 519.0
PYH2_k127_1161199_2 4Fe-4S binding domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000002185 147.0
PYH2_k127_1161199_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000212 143.0
PYH2_k127_119729_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000036 239.0
PYH2_k127_119729_1 G5 domain protein - - - 0.0000000000000000000000000000000001483 139.0
PYH2_k127_1208376_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 6.304e-294 914.0
PYH2_k127_1208376_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 489.0
PYH2_k127_1208376_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007298 244.0
PYH2_k127_1208376_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000002763 70.0
PYH2_k127_12108_0 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000664 202.0
PYH2_k127_1242705_0 Collagenase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 606.0
PYH2_k127_1242705_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 373.0
PYH2_k127_1242705_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 336.0
PYH2_k127_1294723_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 322.0
PYH2_k127_1294723_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000185 273.0
PYH2_k127_1294723_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000008622 232.0
PYH2_k127_1294723_3 small multi-drug export - - - 0.0000000000001704 74.0
PYH2_k127_134347_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 458.0
PYH2_k127_134347_1 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 436.0
PYH2_k127_134347_2 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000000445 179.0
PYH2_k127_1358783_0 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 6.828e-246 765.0
PYH2_k127_1358783_1 Protein of unknown function (DUF4013) - - - 0.0000000000000000000000000000000002047 136.0
PYH2_k127_1442667_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 1.427e-275 855.0
PYH2_k127_1442667_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.656e-250 782.0
PYH2_k127_1442667_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 2.986e-212 667.0
PYH2_k127_1442667_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 475.0
PYH2_k127_1442667_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 0.000000000000001614 76.0
PYH2_k127_1446000_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0 1000.0
PYH2_k127_1446000_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 2.156e-276 855.0
PYH2_k127_1446000_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 561.0
PYH2_k127_1446000_3 PFAM ABC transporter K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 273.0
PYH2_k127_1446000_4 PFAM ABC transporter K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 267.0
PYH2_k127_1446000_5 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000000000000000005984 221.0
PYH2_k127_1446000_6 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.0000000000000000000000000000000000000000000000001318 177.0
PYH2_k127_1469332_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 494.0
PYH2_k127_1469332_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001031 270.0
PYH2_k127_1469332_2 RuvA, C-terminal domain K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000002016 243.0
PYH2_k127_1469332_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001749 210.0
PYH2_k127_1469332_4 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.000000000000000000000000009655 109.0
PYH2_k127_15308_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 569.0
PYH2_k127_15308_1 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 514.0
PYH2_k127_15308_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 457.0
PYH2_k127_15308_3 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 384.0
PYH2_k127_15308_4 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 322.0
PYH2_k127_15308_5 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000001636 240.0
PYH2_k127_1605021_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 529.0
PYH2_k127_1605021_1 - - - - 0.000000000000000000000004478 102.0
PYH2_k127_1609706_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 550.0
PYH2_k127_1609706_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000003773 165.0
PYH2_k127_1609706_2 - K00960 - 2.7.7.6 0.000000000000000000000000000000002125 128.0
PYH2_k127_1609706_3 - - - - 0.00000000136 59.0
PYH2_k127_1657551_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006548 265.0
PYH2_k127_1657551_1 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000000000000000000000002874 224.0
PYH2_k127_1657551_2 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000000003034 134.0
PYH2_k127_1657551_3 Binds to the 23S rRNA K02896 - - 0.0000000000000000000000000000001572 124.0
PYH2_k127_1657551_4 Uncharacterized membrane protein (DUF2298) - - - 0.0002643 43.0
PYH2_k127_1680525_0 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 360.0
PYH2_k127_1680525_1 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000003258 230.0
PYH2_k127_1680525_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000971 167.0
PYH2_k127_1680525_3 PFAM metallophosphoesterase K07096 - - 0.000000006787 58.0
PYH2_k127_1688292_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 451.0
PYH2_k127_1688292_1 Protein of unknown function (DUF460) K09150 - - 0.000000000000000000000000000000000000000000000000003234 192.0
PYH2_k127_1714821_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 516.0
PYH2_k127_1714821_1 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 288.0
PYH2_k127_1817291_0 PFAM Polysaccharide export protein - - - 0.00000000000000000000000000000000000007866 151.0
PYH2_k127_1817291_1 Chain length determinant protein - - - 0.0000000000000000000000000004272 124.0
PYH2_k127_1832323_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 312.0
PYH2_k127_1832323_1 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000002207 53.0
PYH2_k127_1832323_2 Protein of unknown function (DUF2953) - - - 0.000005196 57.0
PYH2_k127_1861986_0 Protein of unknown function, DUF255 K06888 - - 1.454e-267 841.0
PYH2_k127_1861986_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 295.0
PYH2_k127_1861986_2 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004582 282.0
PYH2_k127_1861986_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 271.0
PYH2_k127_1861986_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000001247 129.0
PYH2_k127_1934767_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
PYH2_k127_1934767_1 - - - - 0.000000000000001822 78.0
PYH2_k127_1934767_2 - - - - 0.00000000000004039 76.0
PYH2_k127_1946915_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 4.666e-261 807.0
PYH2_k127_1946915_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 604.0
PYH2_k127_1946915_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 606.0
PYH2_k127_1946915_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 509.0
PYH2_k127_1946915_4 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 481.0
PYH2_k127_1946915_5 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 344.0
PYH2_k127_1946915_6 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001445 230.0
PYH2_k127_1946915_7 cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000003498 150.0
PYH2_k127_1946915_8 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000002959 88.0
PYH2_k127_2030754_0 PFAM Cation K03498 - - 2.932e-229 718.0
PYH2_k127_2030754_1 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 462.0
PYH2_k127_2030754_2 PFAM oxidoreductase nitrogenase, component 1 - - - 0.0000000000000000000000000000000000000000003432 164.0
PYH2_k127_2037425_0 PFAM glycosyl transferase family 39 - - - 2.438e-241 756.0
PYH2_k127_2037425_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 333.0
PYH2_k127_2037425_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000000006183 207.0
PYH2_k127_2037425_3 - - - - 0.00000000000000000000000000000000000000000000002413 173.0
PYH2_k127_2038402_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 429.0
PYH2_k127_2038402_1 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
PYH2_k127_2038402_2 PFAM peptidase zinc-dependent K06974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001605 271.0
PYH2_k127_2038402_3 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000000000000000000000001903 159.0
PYH2_k127_2038402_4 PBS lyase HEAT-like repeat - - - 0.000000000000000000000001035 104.0
PYH2_k127_2157384_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 301.0
PYH2_k127_2157384_1 Methyltransferase domain - - - 0.00000000000000000000000000008178 119.0
PYH2_k127_2169098_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.384e-224 700.0
PYH2_k127_2169098_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000002391 117.0
PYH2_k127_2190390_0 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
PYH2_k127_2190390_1 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006054 273.0
PYH2_k127_2190390_2 - - - - 0.0000000000000000000000000000000000000000000000000005905 207.0
PYH2_k127_2190390_3 MreB/Mbl protein K04043 - - 0.00007285 51.0
PYH2_k127_219092_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.281e-299 923.0
PYH2_k127_219092_1 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 6.003e-267 826.0
PYH2_k127_219092_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 575.0
PYH2_k127_219092_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 491.0
PYH2_k127_219092_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 484.0
PYH2_k127_219092_5 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000007311 236.0
PYH2_k127_219092_6 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000008272 178.0
PYH2_k127_219092_7 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000007335 54.0
PYH2_k127_2287299_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
PYH2_k127_2287299_1 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 260.0
PYH2_k127_2287299_2 TIGRFAM PAS sensor protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000079 257.0
PYH2_k127_2287299_3 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000004753 95.0
PYH2_k127_2287299_4 protein conserved in bacteria (DUF2179) - - - 0.00000000000005947 74.0
PYH2_k127_2287299_5 protein conserved in bacteria (DUF2179) - - - 0.00006381 46.0
PYH2_k127_2338735_0 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 502.0
PYH2_k127_2338735_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
PYH2_k127_2400435_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 585.0
PYH2_k127_2400435_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000003474 222.0
PYH2_k127_2421627_0 nuclease activity K06218,K06408 - - 0.000000000003915 73.0
PYH2_k127_2421627_1 - - - - 0.00000000000496 74.0
PYH2_k127_2450375_0 Involved in regulation of DNA replication K10725 - - 3.852e-211 659.0
PYH2_k127_2450375_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000001613 240.0
PYH2_k127_2450375_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000002922 189.0
PYH2_k127_2450375_3 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000006909 137.0
PYH2_k127_2531_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 488.0
PYH2_k127_2531_1 COG2226 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000002929 129.0
PYH2_k127_2531_2 - - - - 0.0000000001788 62.0
PYH2_k127_2551029_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 556.0
PYH2_k127_2551029_1 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 427.0
PYH2_k127_2551029_2 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 335.0
PYH2_k127_2551029_3 COG1202 Superfamily II helicase, archaea-specific - - - 0.0000000008418 59.0
PYH2_k127_2631709_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 1.781e-213 669.0
PYH2_k127_2631709_1 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 297.0
PYH2_k127_2631709_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000001535 193.0
PYH2_k127_2674309_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 442.0
PYH2_k127_2674309_1 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000008576 201.0
PYH2_k127_2702631_0 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 565.0
PYH2_k127_2702631_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 260.0
PYH2_k127_2702631_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000002233 61.0
PYH2_k127_2750962_0 TIGRFAM PAS sensor protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 465.0
PYH2_k127_2750962_1 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000003702 93.0
PYH2_k127_2765743_0 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 584.0
PYH2_k127_2765743_1 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 389.0
PYH2_k127_2765743_2 - - - - 0.000000000000000000000000000000000000000000000000007357 185.0
PYH2_k127_2765743_3 - - - - 0.000000000000000000000000000000005086 134.0
PYH2_k127_2765743_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000001889 81.0
PYH2_k127_2854639_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006555 273.0
PYH2_k127_2854639_1 ATPase activity K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000003378 193.0
PYH2_k127_2891189_0 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000358 226.0
PYH2_k127_2891189_1 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000001416 93.0
PYH2_k127_2904826_0 PFAM SufBD protein K07033 - - 5.358e-207 647.0
PYH2_k127_2904826_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 314.0
PYH2_k127_2904826_2 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
PYH2_k127_2904826_3 PFAM cyclase family protein K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
PYH2_k127_2904826_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
PYH2_k127_2904826_5 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000003892 174.0
PYH2_k127_2907503_0 membrane-anchored protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000007432 205.0
PYH2_k127_295140_0 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001802 246.0
PYH2_k127_295140_1 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000006683 156.0
PYH2_k127_295140_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000002125 145.0
PYH2_k127_295140_3 - - - - 0.000000000000000000001231 100.0
PYH2_k127_295140_4 - - - - 0.00000000000000001143 85.0
PYH2_k127_295140_5 Domain of unknown function (DUF362) - - - 0.000000007456 57.0
PYH2_k127_305965_0 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000000000000000002501 175.0
PYH2_k127_305965_1 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07324,K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000331 132.0
PYH2_k127_305965_2 - - - - 0.000000000000000000000009021 104.0
PYH2_k127_3080483_0 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 5.019e-194 609.0
PYH2_k127_3080483_1 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 493.0
PYH2_k127_3080483_2 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000006761 224.0
PYH2_k127_3080483_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000003542 58.0
PYH2_k127_3080483_4 small metal-binding protein - - - 0.00003749 48.0
PYH2_k127_3089079_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 311.0
PYH2_k127_3089079_1 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000001998 210.0
PYH2_k127_3089079_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000000000000004358 182.0
PYH2_k127_3089079_3 - - - - 0.00000000000000000000000000000000000003245 146.0
PYH2_k127_3089079_4 PFAM Beta propeller domain K14475 - - 0.000000000000000000000000001641 117.0
PYH2_k127_3089079_5 - - - - 0.0000000000000000000001447 99.0
PYH2_k127_3089079_6 PFAM aminotransferase class V - - - 0.000000000000000008685 85.0
PYH2_k127_3089079_7 Pfam:Pyridox_oxidase K07006 - - 0.0000000241 61.0
PYH2_k127_311321_0 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 604.0
PYH2_k127_311321_1 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
PYH2_k127_3175443_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006242 246.0
PYH2_k127_3175443_1 - - - - 0.000006919 55.0
PYH2_k127_3192763_0 2Fe-2S iron-sulfur cluster binding domain - - - 8.135e-265 820.0
PYH2_k127_3192763_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 547.0
PYH2_k127_3192763_2 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 402.0
PYH2_k127_3192763_3 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 338.0
PYH2_k127_3192763_4 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 302.0
PYH2_k127_3192763_5 Heat shock protein - - - 0.00000002548 62.0
PYH2_k127_3285441_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 458.0
PYH2_k127_3312782_0 Anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 469.0
PYH2_k127_3312782_2 Histidine kinase K07651 - 2.7.13.3 0.00002396 52.0
PYH2_k127_3314807_0 transmembrane transport K01992 - - 0.0000000000002882 80.0
PYH2_k127_3314807_1 - - - - 0.00000001954 64.0
PYH2_k127_3317980_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 567.0
PYH2_k127_3317980_1 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 530.0
PYH2_k127_3317980_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 481.0
PYH2_k127_3317980_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000139 142.0
PYH2_k127_3352628_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 5.199e-235 729.0
PYH2_k127_3352628_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 430.0
PYH2_k127_3352628_2 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.0000000000000000000000000000000000000000000005135 171.0
PYH2_k127_3352628_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000000000000006812 107.0
PYH2_k127_3352628_4 archaeal coiled-coil protein - - - 0.00000000005002 63.0
PYH2_k127_3392206_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 456.0
PYH2_k127_3392206_1 Glycosyltransferase, group 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 416.0
PYH2_k127_3392206_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 349.0
PYH2_k127_3392206_4 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000002813 150.0
PYH2_k127_3392206_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000003476 116.0
PYH2_k127_3392206_6 Transposase K07497 - - 0.00000000000000000001551 92.0
PYH2_k127_3424154_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 7.766e-207 648.0
PYH2_k127_3424154_1 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 328.0
PYH2_k127_3424154_2 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 280.0
PYH2_k127_3424154_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001435 266.0
PYH2_k127_3424154_4 PFAM Methyltransferase type - - - 0.0000000000376 64.0
PYH2_k127_3427316_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 4.641e-202 637.0
PYH2_k127_3427316_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 304.0
PYH2_k127_3427316_2 Domain of unknown function (DUF333) K14475 - - 0.00000000000000000000001465 108.0
PYH2_k127_3481644_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 4e-208 653.0
PYH2_k127_3481644_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 502.0
PYH2_k127_3481644_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 491.0
PYH2_k127_3481644_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 471.0
PYH2_k127_3481644_4 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 374.0
PYH2_k127_3481644_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
PYH2_k127_3481644_6 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
PYH2_k127_3511496_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4e-208 652.0
PYH2_k127_3511496_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 369.0
PYH2_k127_3511496_2 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
PYH2_k127_3511496_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000005241 182.0
PYH2_k127_3511496_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000004979 121.0
PYH2_k127_3511496_5 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000001692 109.0
PYH2_k127_3518015_0 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 550.0
PYH2_k127_3518015_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 495.0
PYH2_k127_3518015_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 425.0
PYH2_k127_3518015_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 391.0
PYH2_k127_3518015_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000007467 95.0
PYH2_k127_3518015_5 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000000002054 81.0
PYH2_k127_3521490_0 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 428.0
PYH2_k127_3521490_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 375.0
PYH2_k127_3521490_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 314.0
PYH2_k127_3521490_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000331 182.0
PYH2_k127_3594066_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 1.401e-221 693.0
PYH2_k127_3594066_1 PFAM oxidoreductase domain protein K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 424.0
PYH2_k127_3594066_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001873 276.0
PYH2_k127_3602441_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 1.143e-305 947.0
PYH2_k127_3602441_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 2.124e-240 752.0
PYH2_k127_3602441_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 545.0
PYH2_k127_3602441_3 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000003702 263.0
PYH2_k127_3602441_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006898 250.0
PYH2_k127_3602441_5 Belongs to the UPF0212 family K09731 - - 0.00000000000000000000000000000000000000000000000000000008285 196.0
PYH2_k127_3602441_6 Family of unknown function (DUF5350) - - - 0.00000000000000000000000000000000000000000008633 161.0
PYH2_k127_3602441_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000004001 141.0
PYH2_k127_3614255_0 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 417.0
PYH2_k127_3614255_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 376.0
PYH2_k127_3614255_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 374.0
PYH2_k127_3614255_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 369.0
PYH2_k127_3614255_4 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000002034 196.0
PYH2_k127_3636042_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 3.253e-201 634.0
PYH2_k127_3636042_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 317.0
PYH2_k127_3636042_2 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 302.0
PYH2_k127_3636042_3 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000002322 242.0
PYH2_k127_3636042_4 TfuA-like protein - - - 0.00000000000000000000000000000000000000000000000007052 184.0
PYH2_k127_3636042_5 PFAM Tetratricopeptide repeat - - - 0.00000000000008699 72.0
PYH2_k127_3657090_0 TIGRFAM UbiD family - - - 4.108e-216 676.0
PYH2_k127_3657090_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000009992 235.0
PYH2_k127_3657090_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
PYH2_k127_3657090_3 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000001213 170.0
PYH2_k127_3679800_0 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 312.0
PYH2_k127_3679800_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 284.0
PYH2_k127_3679800_2 Small multi-drug export protein - - - 0.0000000000000000000000000000000000000000008916 165.0
PYH2_k127_3723373_0 CBS domain containing protein - - - 2.921e-208 653.0
PYH2_k127_3723373_1 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 309.0
PYH2_k127_3723373_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.00000000000000000000000000000000000000000001564 164.0
PYH2_k127_3723373_3 CRS1_YhbY K07574 - - 0.00000000000000000000000000005597 117.0
PYH2_k127_3728848_0 Belongs to the glutamate synthase family - - - 1.175e-294 908.0
PYH2_k127_3728848_1 PFAM glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 511.0
PYH2_k127_3728848_2 PFAM glutamate synthase alpha subunit domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 399.0
PYH2_k127_3728848_3 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000001327 187.0
PYH2_k127_3763057_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 603.0
PYH2_k127_3763057_1 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 377.0
PYH2_k127_3763057_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000001195 173.0
PYH2_k127_3767033_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
PYH2_k127_3767033_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000001029 167.0
PYH2_k127_3767033_2 Alpha beta hydrolase superfamily K01563 - 3.8.1.5 0.000000000000000000000000000000000001472 140.0
PYH2_k127_3767033_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.0000000000000000000000000000911 120.0
PYH2_k127_3767033_4 - - - - 0.000000000000000000017 98.0
PYH2_k127_3767033_5 - - - - 0.0000000000007072 76.0
PYH2_k127_3767033_6 Alpha beta hydrolase K01563,K22318 - 3.8.1.5 0.000001929 56.0
PYH2_k127_3769674_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 1.785e-272 853.0
PYH2_k127_3769674_1 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 518.0
PYH2_k127_3769674_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000003944 195.0
PYH2_k127_3769674_3 - - - - 0.00000000000000000009428 91.0
PYH2_k127_3785872_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 591.0
PYH2_k127_3785872_1 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 462.0
PYH2_k127_3785872_2 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 382.0
PYH2_k127_3785872_3 PFAM Glycosyl transferase family 2 K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 311.0
PYH2_k127_3864079_0 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005311 229.0
PYH2_k127_3864079_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000003158 209.0
PYH2_k127_3864079_2 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000002027 91.0
PYH2_k127_4122880_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1249.0
PYH2_k127_4122880_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 343.0
PYH2_k127_4147226_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 448.0
PYH2_k127_4147226_1 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 372.0
PYH2_k127_4147226_2 - - - - 0.00000000000000000000000000000000000003505 144.0
PYH2_k127_4147226_3 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000149 72.0
PYH2_k127_4147226_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000008102 63.0
PYH2_k127_4147226_5 Belongs to the SOS response-associated peptidase family - - - 0.00000525 50.0
PYH2_k127_4195429_0 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 484.0
PYH2_k127_4195429_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 297.0
PYH2_k127_4195429_2 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 297.0
PYH2_k127_4195429_3 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009045 272.0
PYH2_k127_4195429_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000000003464 169.0
PYH2_k127_4232878_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.368e-233 727.0
PYH2_k127_4232878_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07652 - 2.7.13.3 3.259e-204 651.0
PYH2_k127_4232878_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 560.0
PYH2_k127_4232878_3 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000000000000007775 169.0
PYH2_k127_4248286_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000001342 135.0
PYH2_k127_4248286_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000002615 65.0
PYH2_k127_4295171_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 557.0
PYH2_k127_4295171_1 - - - - 0.000000000000000000000000000000000001045 141.0
PYH2_k127_4295171_2 - - - - 0.00000000000000000000000000000002335 134.0
PYH2_k127_4295171_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000274 94.0
PYH2_k127_4295171_4 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000101 78.0
PYH2_k127_4295171_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000008041 66.0
PYH2_k127_4295171_6 PFAM Tetratricopeptide repeat - - - 0.0000000001157 63.0
PYH2_k127_4295171_7 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00001405 48.0
PYH2_k127_4360828_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 556.0
PYH2_k127_4360828_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 390.0
PYH2_k127_4360828_2 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 353.0
PYH2_k127_4360828_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000007816 265.0
PYH2_k127_4360828_4 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000002519 252.0
PYH2_k127_4399730_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1932.0
PYH2_k127_4399730_1 - - - - 0.00000000000000000000000000000000000000000000000000003898 192.0
PYH2_k127_4399730_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000004597 169.0
PYH2_k127_4399730_3 - - - - 0.0003054 47.0
PYH2_k127_4424173_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 605.0
PYH2_k127_4424173_1 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 474.0
PYH2_k127_4424173_2 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
PYH2_k127_443084_0 LOR SDH bifunctional enzyme conserved - - - 8.858e-221 691.0
PYH2_k127_443084_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 488.0
PYH2_k127_44905_0 in RNase L inhibitor, RLI K06174 - - 0.0 1057.0
PYH2_k127_44905_1 RNase L inhibitor, RLI - - - 0.00000000000000000000000000000000000000000000000001698 183.0
PYH2_k127_4530425_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000007607 132.0
PYH2_k127_4530425_1 alginic acid biosynthetic process - - - 0.000000000000000000000000189 117.0
PYH2_k127_4643223_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.768e-284 878.0
PYH2_k127_4643223_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000000000000000000000000000000000000005749 198.0
PYH2_k127_4643223_2 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000004796 147.0
PYH2_k127_4677876_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.592e-231 719.0
PYH2_k127_4677876_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 308.0
PYH2_k127_4677876_2 - - - - 0.000000000000000000000000000000000000000000000000000001448 197.0
PYH2_k127_4677876_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000002419 62.0
PYH2_k127_476688_0 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 417.0
PYH2_k127_476688_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000001199 127.0
PYH2_k127_4812980_0 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000000007039 157.0
PYH2_k127_4812980_1 addiction module antidote protein HigA K21498 - - 0.00000000000000000000000000000000000000005271 152.0
PYH2_k127_4812980_2 Protein of unknown function (DUF2283) - - - 0.0000000000000000000000000721 108.0
PYH2_k127_4812980_3 Involved in initiation control of chromosome replication - - - 0.00000000000000001126 84.0
PYH2_k127_4812980_4 - - - - 0.000000008137 60.0
PYH2_k127_4821609_0 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000006412 233.0
PYH2_k127_4821609_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000005407 166.0
PYH2_k127_4848848_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 1.926e-231 722.0
PYH2_k127_4848848_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 596.0
PYH2_k127_4848848_2 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
PYH2_k127_4848848_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 312.0
PYH2_k127_4848848_4 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002535 269.0
PYH2_k127_4848848_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001824 225.0
PYH2_k127_4848848_6 Domain of unknown function (DUF1805) - - - 0.00000000000000000000000000000000000000000004735 162.0
PYH2_k127_4848848_7 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000000000000005867 161.0
PYH2_k127_48696_0 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 597.0
PYH2_k127_48696_1 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 494.0
PYH2_k127_48696_2 - K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004073 274.0
PYH2_k127_48696_3 PBS lyase K22221 - - 0.00001102 49.0
PYH2_k127_4902137_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.014e-285 878.0
PYH2_k127_4902137_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 470.0
PYH2_k127_4902137_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 328.0
PYH2_k127_4902137_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000334 245.0
PYH2_k127_4902137_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000005871 106.0
PYH2_k127_4902137_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000002139 87.0
PYH2_k127_4918040_0 Belongs to the glycosyl hydrolase 2 family - - - 2.475e-222 704.0
PYH2_k127_4918040_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 291.0
PYH2_k127_4918040_2 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 286.0
PYH2_k127_4918040_3 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
PYH2_k127_4918040_4 Flavodoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
PYH2_k127_4918040_5 - - - - 0.0000000001443 63.0
PYH2_k127_491941_0 PFAM major facilitator superfamily MFS_1 - - - 9.186e-202 638.0
PYH2_k127_491941_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 404.0
PYH2_k127_491941_2 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
PYH2_k127_491941_3 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000118 266.0
PYH2_k127_491941_4 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000008493 169.0
PYH2_k127_491941_5 HI0933 family K07007 - - 0.00000000000000000000000000000000000000002379 155.0
PYH2_k127_491941_6 - - - - 0.0000000000000000000000000000000000003435 145.0
PYH2_k127_491941_7 HI0933-like protein K07007 - - 0.0008562 43.0
PYH2_k127_4941364_0 metallopeptidase activity K01179,K20276 - 3.2.1.4 0.00000000000001031 88.0
PYH2_k127_4941364_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000009259 56.0
PYH2_k127_4941364_3 PFAM response regulator receiver - - - 0.0000002354 59.0
PYH2_k127_4941364_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0003975 53.0
PYH2_k127_4965030_0 TIR domain - - - 0.00000000000000000000000000000000000000000000001856 189.0
PYH2_k127_4965030_2 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000072 68.0
PYH2_k127_5037800_0 PFAM dihydropteroate synthase, DHPS - - - 5.204e-224 703.0
PYH2_k127_5037800_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 383.0
PYH2_k127_5037800_2 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 359.0
PYH2_k127_5037800_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
PYH2_k127_5037800_4 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000000000000000000000000000000007395 204.0
PYH2_k127_5037800_5 metal-dependent phosphoesterases (PHP family) - - - 0.0000000000000000000000000000000000000000000001007 176.0
PYH2_k127_5037800_6 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000009127 164.0
PYH2_k127_5037800_7 Predicted metal-binding protein (DUF2284) - - - 0.0000395 46.0
PYH2_k127_5056932_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 419.0
PYH2_k127_5087477_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 7.119e-253 783.0
PYH2_k127_5087477_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 480.0
PYH2_k127_5087477_2 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001255 258.0
PYH2_k127_5087477_3 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000002021 189.0
PYH2_k127_5114454_0 Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 509.0
PYH2_k127_5114454_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000003638 219.0
PYH2_k127_5118552_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001389 295.0
PYH2_k127_5118552_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000001692 101.0
PYH2_k127_5132953_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 381.0
PYH2_k127_5132953_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 317.0
PYH2_k127_5132953_2 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002763 263.0
PYH2_k127_5132953_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001793 258.0
PYH2_k127_5132953_4 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000008671 246.0
PYH2_k127_520586_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000546 156.0
PYH2_k127_520586_1 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000689 111.0
PYH2_k127_5262823_0 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
PYH2_k127_5262823_1 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 270.0
PYH2_k127_5262823_2 Predicted membrane protein (DUF2105) K14098 - - 0.00000000000000000000000000000000000000000000000000000000003211 212.0
PYH2_k127_5262823_3 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.00000000000000000000000000000000000000000000000002279 184.0
PYH2_k127_5262823_4 NiFe -hydrogenase-3-type complex Eha, membrane protein EhaE K14096 - - 0.00000000000000000001535 94.0
PYH2_k127_5262823_5 Predicted membrane protein (DUF2108) K14095 - - 0.00000000007634 64.0
PYH2_k127_5282073_0 PFAM peptidase M50 - - - 5.286e-209 656.0
PYH2_k127_5282073_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 449.0
PYH2_k127_5282073_2 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 391.0
PYH2_k127_5282073_3 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 366.0
PYH2_k127_5282073_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000006027 128.0
PYH2_k127_5282073_5 PFAM response regulator receiver - - - 0.000003296 50.0
PYH2_k127_5321898_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 583.0
PYH2_k127_5321898_1 membrane-associated protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
PYH2_k127_5321898_2 - - - - 0.0000000000000000000000000000126 128.0
PYH2_k127_536758_0 TonB-dependent receptor K02014 - - 7.701e-238 754.0
PYH2_k127_5379773_0 Transport of potassium into the cell K03549 - - 3.138e-293 910.0
PYH2_k127_5379773_1 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 409.0
PYH2_k127_5379773_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 360.0
PYH2_k127_5379773_3 - - - - 0.000000000000000000000000000000000000000000000000000000003209 207.0
PYH2_k127_5379773_4 - - - - 0.000000000000000000000000000001221 130.0
PYH2_k127_5403110_0 PFAM Thiolase K00626 - 2.3.1.9 6.34e-221 688.0
PYH2_k127_5403110_1 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 3e-212 667.0
PYH2_k127_5403110_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 4.388e-195 612.0
PYH2_k127_5403110_3 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
PYH2_k127_5403110_4 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 360.0
PYH2_k127_5403110_5 Helix-turn-helix domain protein K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001134 258.0
PYH2_k127_5403110_6 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000134 252.0
PYH2_k127_5403110_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000002909 231.0
PYH2_k127_5403110_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000002424 117.0
PYH2_k127_5435841_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 8.995e-223 695.0
PYH2_k127_5435841_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 2.687e-204 640.0
PYH2_k127_5435841_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000005813 140.0
PYH2_k127_5435841_3 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.0000000000000000000009421 101.0
PYH2_k127_5535210_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 1.496e-206 643.0
PYH2_k127_5535210_1 Glycosyltransferase 28 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 454.0
PYH2_k127_5535210_10 - - - - 0.000000000000003865 81.0
PYH2_k127_5535210_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 398.0
PYH2_k127_5535210_3 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 348.0
PYH2_k127_5535210_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001501 251.0
PYH2_k127_5535210_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005057 248.0
PYH2_k127_5535210_6 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
PYH2_k127_5535210_7 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000000000000000000000000000000000000362 162.0
PYH2_k127_5535210_8 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000000000000000000000002399 141.0
PYH2_k127_5535210_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000000000000000000000000343 136.0
PYH2_k127_55954_0 TonB dependent receptor K02014 - - 1.29e-232 734.0
PYH2_k127_5637810_0 uridine kinase - - - 0.000000000000000000000000007043 118.0
PYH2_k127_569646_0 V-type ATP synthase, subunit I K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 308.0
PYH2_k127_569646_1 ATP synthase subunit K K02124 - - 0.00000000000000000000000000000000000000000002462 166.0
PYH2_k127_569646_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000003091 163.0
PYH2_k127_569646_3 - K14093 - - 0.00000000000000000000000000000000000002048 146.0
PYH2_k127_571391_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.5e-280 873.0
PYH2_k127_571391_1 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000004241 193.0
PYH2_k127_571391_2 Archaeal Nre, N-terminal - - - 0.0000000000000000000000002149 107.0
PYH2_k127_571391_3 Archaeal Nre, N-terminal - - - 0.000001831 55.0
PYH2_k127_5754831_0 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 491.0
PYH2_k127_5754831_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 310.0
PYH2_k127_5754831_2 Putative transposase DNA-binding domain K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 263.0
PYH2_k127_5763467_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1699.0
PYH2_k127_5765083_0 TIGRFAM small GTP-binding protein K06944 - - 1.165e-206 647.0
PYH2_k127_5765083_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 529.0
PYH2_k127_5780253_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
PYH2_k127_5780253_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000005488 220.0
PYH2_k127_5788849_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 2.335e-199 625.0
PYH2_k127_5788849_1 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 520.0
PYH2_k127_5788849_2 Phage plasmid primase, P4 K06919 - - 0.000000000000000000000000001491 116.0
PYH2_k127_5788849_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000201 79.0
PYH2_k127_5808486_0 PFAM amino acid-binding ACT domain protein K06862 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 396.0
PYH2_k127_5808486_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
PYH2_k127_5808486_2 FHA domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000001499 201.0
PYH2_k127_5808486_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000007709 77.0
PYH2_k127_5817204_0 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 368.0
PYH2_k127_5817204_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000001578 258.0
PYH2_k127_5817204_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000005236 246.0
PYH2_k127_583361_0 Belongs to the UPF0280 family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 373.0
PYH2_k127_583361_1 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003918 263.0
PYH2_k127_583361_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000257 223.0
PYH2_k127_583361_3 - - - - 0.00000000000000000000000000000000000000000002548 168.0
PYH2_k127_5836423_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 1.577e-306 950.0
PYH2_k127_5836423_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 249.0
PYH2_k127_5889787_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 456.0
PYH2_k127_5889787_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 307.0
PYH2_k127_5889787_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 301.0
PYH2_k127_5889787_3 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000000000000004392 164.0
PYH2_k127_5929926_0 PFAM ABC transporter K00400 - - 5.651e-302 930.0
PYH2_k127_5929926_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 489.0
PYH2_k127_5929926_2 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 450.0
PYH2_k127_5929926_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001431 277.0
PYH2_k127_5935737_0 Domain of unknown function DUF128 K21640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 373.0
PYH2_k127_5935737_1 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 315.0
PYH2_k127_5935737_2 PFAM transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000002161 203.0
PYH2_k127_5935737_3 - - - - 0.000000000005141 66.0
PYH2_k127_593846_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 560.0
PYH2_k127_593846_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 415.0
PYH2_k127_5968560_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 466.0
PYH2_k127_5968560_1 -O-antigen K02847,K13009 - - 0.000000000000000000000000000000000000000000000000000001024 207.0
PYH2_k127_5968560_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000001458 139.0
PYH2_k127_5968560_3 Methyltransferase domain - - - 0.0000000000000000000000523 107.0
PYH2_k127_5968560_4 Chain length determinant protein - - - 0.000000000003152 71.0
PYH2_k127_5981782_0 PFAM TM2 domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 329.0
PYH2_k127_5981782_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000005219 231.0
PYH2_k127_5981782_2 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000068 217.0
PYH2_k127_5981782_3 Activator of Hsp90 ATPase, N-terminal - GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006950,GO:0008047,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0030234,GO:0032781,GO:0033554,GO:0034605,GO:0043085,GO:0043462,GO:0044093,GO:0044424,GO:0044464,GO:0050790,GO:0050896,GO:0051087,GO:0051336,GO:0051345,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000004339 109.0
PYH2_k127_6036180_0 PFAM type II secretion system protein E K07332 - - 0.0 1020.0
PYH2_k127_6036180_1 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 350.0
PYH2_k127_6046873_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.00000000000000000000000000000000000000000000000000002652 195.0
PYH2_k127_6046873_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000001537 119.0
PYH2_k127_6046873_2 - - - - 0.0000000000000007703 81.0
PYH2_k127_6046873_3 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.0000000000512 65.0
PYH2_k127_6046873_5 SPFH domain-Band 7 family - - - 0.0006041 51.0
PYH2_k127_6068531_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 413.0
PYH2_k127_6068531_1 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 318.0
PYH2_k127_6068531_2 Mn-dependent transcriptional regulator K03709 - - 0.00000000000000000000000000000000000000004376 159.0
PYH2_k127_6068531_3 Phage plasmid primase, P4 K06919 - - 0.00000000000000000000000000000000007472 141.0
PYH2_k127_6068531_4 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000004402 90.0
PYH2_k127_6068531_5 Ferrous iron transport B domain protein K04759 - - 0.0003521 45.0
PYH2_k127_6118695_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 531.0
PYH2_k127_6118695_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 424.0
PYH2_k127_6118695_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000176 127.0
PYH2_k127_6118695_3 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.000000001222 59.0
PYH2_k127_6118695_4 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000001503 59.0
PYH2_k127_6120383_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 6.671e-200 629.0
PYH2_k127_6120383_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 532.0
PYH2_k127_6120383_2 Cysteine-rich small domain K08260 - 3.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 422.0
PYH2_k127_6120383_3 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 337.0
PYH2_k127_6120383_4 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006281 231.0
PYH2_k127_6120383_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000002526 226.0
PYH2_k127_6120383_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000006196 187.0
PYH2_k127_6120383_7 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000004335 114.0
PYH2_k127_6120383_8 DNA modification - - - 0.00005064 49.0
PYH2_k127_6120383_9 COG1002 Type II restriction enzyme, methylase subunits - - - 0.00008661 46.0
PYH2_k127_61324_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.446e-196 620.0
PYH2_k127_61324_1 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000127 162.0
PYH2_k127_6140272_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 503.0
PYH2_k127_6140272_1 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000214 170.0
PYH2_k127_6167970_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 376.0
PYH2_k127_6167970_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001897 217.0
PYH2_k127_6167970_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000002902 164.0
PYH2_k127_6326270_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 303.0
PYH2_k127_6326270_1 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 267.0
PYH2_k127_6326270_2 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000563 207.0
PYH2_k127_6326270_3 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.000000000000000000000000005361 117.0
PYH2_k127_6326270_4 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000005388 108.0
PYH2_k127_6326270_6 Acid phosphatase homologues - - - 0.00000003031 56.0
PYH2_k127_6326270_7 Rubrerythrin K19824 - - 0.0005037 51.0
PYH2_k127_6341177_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1112.0
PYH2_k127_6341177_1 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 1.111e-226 710.0
PYH2_k127_6341177_2 Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor K00918 - 2.7.1.146,2.7.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 483.0
PYH2_k127_6351240_0 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 593.0
PYH2_k127_6367333_0 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 508.0
PYH2_k127_6367333_1 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 383.0
PYH2_k127_6367333_2 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000006041 131.0
PYH2_k127_6420179_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 496.0
PYH2_k127_6420179_1 - - - - 0.0000000000000000000000000000421 118.0
PYH2_k127_6420179_2 PspC domain K03973 - - 0.0000000000001549 70.0
PYH2_k127_6420179_3 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000004329 67.0
PYH2_k127_6424396_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 497.0
PYH2_k127_6424396_1 - - - - 0.000000000000000000000000000000000000000000006884 164.0
PYH2_k127_6431277_0 DEAD DEAH box helicase K03724 - - 9.771e-272 853.0
PYH2_k127_6431277_1 O-methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 253.0
PYH2_k127_6431277_2 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000005053 195.0
PYH2_k127_6431277_3 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000001191 164.0
PYH2_k127_6431277_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000003109 95.0
PYH2_k127_6486248_0 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 526.0
PYH2_k127_6486248_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 331.0
PYH2_k127_6510770_0 hmm pf01609 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 458.0
PYH2_k127_6510770_1 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0001499 45.0
PYH2_k127_6550718_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1140.0
PYH2_k127_6557816_0 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 436.0
PYH2_k127_6557816_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 397.0
PYH2_k127_6557816_2 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000003616 114.0
PYH2_k127_6557816_3 Amino acid adenylation domain - - - 0.00002085 49.0
PYH2_k127_656639_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 2.478e-282 872.0
PYH2_k127_656639_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 4.601e-224 702.0
PYH2_k127_656639_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 474.0
PYH2_k127_656639_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000001422 123.0
PYH2_k127_6579797_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 3.828e-213 667.0
PYH2_k127_6579797_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 442.0
PYH2_k127_6581250_0 KH, type 1, domain K07041 - - 0.0 1228.0
PYH2_k127_6581250_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 492.0
PYH2_k127_6581250_2 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 464.0
PYH2_k127_6581250_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 372.0
PYH2_k127_6581250_4 COG0589 Universal stress protein UspA and related nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000007395 204.0
PYH2_k127_6581250_5 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000006132 154.0
PYH2_k127_6581250_6 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000001417 104.0
PYH2_k127_6581250_7 but it may be involved in stabilization of the trimeric complex - - - 0.0000000000000000000001006 98.0
PYH2_k127_6629434_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 3.213e-215 672.0
PYH2_k127_6629434_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 449.0
PYH2_k127_6629434_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 309.0
PYH2_k127_6629434_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 251.0
PYH2_k127_6629434_4 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000000000000000000003467 214.0
PYH2_k127_6632521_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 3.912e-208 650.0
PYH2_k127_6632521_1 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
PYH2_k127_6633093_0 PFAM PilT protein domain protein K06865 - - 0.0 1089.0
PYH2_k127_6633093_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000000000152 216.0
PYH2_k127_6641343_0 - - - - 0.00000000000001317 81.0
PYH2_k127_6719441_0 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 491.0
PYH2_k127_6719441_1 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 305.0
PYH2_k127_6719441_2 amino acid K16263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003855 278.0
PYH2_k127_6719441_3 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002065 253.0
PYH2_k127_6719441_4 Acetyltransferase (GNAT) domain - - - 0.0000006066 51.0
PYH2_k127_6728340_0 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 492.0
PYH2_k127_6728340_1 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 430.0
PYH2_k127_6728340_2 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006042 250.0
PYH2_k127_6728340_3 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
PYH2_k127_6728340_4 Protein of unknown function (DUF3006) - - - 0.00000000000000006248 82.0
PYH2_k127_6734840_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.181e-264 818.0
PYH2_k127_6734840_1 PFAM PUA domain containing protein K07575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001651 261.0
PYH2_k127_6734840_2 Pfam:DUF552 K09152 - - 0.0000000000000000000000000000000000000000000000000000000000000001355 222.0
PYH2_k127_6734840_3 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
PYH2_k127_6734840_4 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000000000000000000002123 147.0
PYH2_k127_6734840_5 binds to the 23S rRNA K02922 - - 0.000000000000000000000000000003668 119.0
PYH2_k127_6744209_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.039e-224 700.0
PYH2_k127_6744209_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 363.0
PYH2_k127_6744209_2 PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 361.0
PYH2_k127_6744209_3 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000000001765 212.0
PYH2_k127_6744209_4 Molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000486 204.0
PYH2_k127_6744209_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000008366 190.0
PYH2_k127_6744209_6 Transcriptional regulator K07108 - - 0.000000000000000000000000000000000000000006055 156.0
PYH2_k127_6744209_7 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000000003669 133.0
PYH2_k127_6751889_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1175.0
PYH2_k127_6751889_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 340.0
PYH2_k127_6751889_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
PYH2_k127_6751889_3 VIT family - - - 0.00000000000000000000000000000000003547 137.0
PYH2_k127_6774273_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.091e-274 852.0
PYH2_k127_6774273_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 545.0
PYH2_k127_6774273_2 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 527.0
PYH2_k127_6774273_3 transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004201 275.0
PYH2_k127_6784891_0 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 2.999e-231 726.0
PYH2_k127_6784891_1 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 315.0
PYH2_k127_6784891_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 297.0
PYH2_k127_6784891_3 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004676 266.0
PYH2_k127_6796760_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 517.0
PYH2_k127_6796760_1 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 467.0
PYH2_k127_6796760_2 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 380.0
PYH2_k127_6796760_3 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 374.0
PYH2_k127_6796760_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 290.0
PYH2_k127_6825739_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
PYH2_k127_6825739_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 293.0
PYH2_k127_6886233_0 SMART Elongator protein 3 MiaB NifB - - - 1.591e-286 886.0
PYH2_k127_6886233_1 phosphoesterase RecJ domain protein - - - 1.316e-267 829.0
PYH2_k127_6886233_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 321.0
PYH2_k127_6886233_3 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 279.0
PYH2_k127_6886233_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000001203 115.0
PYH2_k127_6900732_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 534.0
PYH2_k127_6900732_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 469.0
PYH2_k127_6900732_2 Domain of unknown function (DUF1917) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 371.0
PYH2_k127_6900732_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 353.0
PYH2_k127_6900732_4 PFAM Transglutaminase-like - - - 0.00000000000000000000000000000000000000003489 160.0
PYH2_k127_6900732_5 - - - - 0.000000000000000000000000000000000000001354 147.0
PYH2_k127_6907337_0 SMART PAS domain containing protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 441.0
PYH2_k127_6907337_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 307.0
PYH2_k127_6907337_2 - - - - 0.000000002296 62.0
PYH2_k127_6914678_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 6.214e-265 820.0
PYH2_k127_6914678_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 8.589e-246 769.0
PYH2_k127_6914678_2 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 506.0
PYH2_k127_6914678_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 456.0
PYH2_k127_6914678_4 6-phosphogluconolactonase activity - - - 0.00000000000000000000001606 119.0
PYH2_k127_6932632_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 460.0
PYH2_k127_6932632_1 Beta-ketoacyl synthase, C-terminal domain - - - 0.000000000000000000000000000000000000003207 150.0
PYH2_k127_6932632_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000005988 132.0
PYH2_k127_6932632_3 - - - - 0.00009677 52.0
PYH2_k127_6932632_4 - - - - 0.0004289 50.0
PYH2_k127_6956664_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 459.0
PYH2_k127_6956664_1 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 409.0
PYH2_k127_6956664_2 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 333.0
PYH2_k127_6956664_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 282.0
PYH2_k127_6956664_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000007579 227.0
PYH2_k127_6956664_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000000000000000000000000000000000000000000000002805 178.0
PYH2_k127_6956664_6 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000000000000000000338 174.0
PYH2_k127_6956664_7 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000344 102.0
PYH2_k127_6956664_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000004162 96.0
PYH2_k127_6956664_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00003453 46.0
PYH2_k127_6971735_0 Glycogen debranching enzyme N terminal - - - 2.844e-250 781.0
PYH2_k127_6971735_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 537.0
PYH2_k127_6971735_2 DGC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001524 241.0
PYH2_k127_6971735_3 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000007114 138.0
PYH2_k127_6971735_4 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000000000000000000003163 132.0
PYH2_k127_6971735_5 - - - - 0.0000000000000000000000000006349 116.0
PYH2_k127_6971735_6 - - - - 0.0000000000000000000000002473 107.0
PYH2_k127_6971735_7 Intracellular protease, PfpI K05520 - 3.5.1.124 0.00000000000000000002623 94.0
PYH2_k127_6971735_8 ubiquitin protein ligase activity K16276 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0019941,GO:0030003,GO:0030163,GO:0031667,GO:0031668,GO:0031669,GO:0032446,GO:0032501,GO:0033554,GO:0036211,GO:0042592,GO:0042594,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048871,GO:0048878,GO:0050801,GO:0050896,GO:0051603,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060586,GO:0061630,GO:0061659,GO:0065007,GO:0065008,GO:0070647,GO:0071496,GO:0071704,GO:0098771,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000001658 79.0
PYH2_k127_6971735_9 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000001411 56.0
PYH2_k127_6976821_0 PFAM acyl-CoA dehydrogenase domain protein - - - 1.679e-197 620.0
PYH2_k127_6976821_1 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 522.0
PYH2_k127_6976821_2 Non-ribosomal peptide synthetase modules and related proteins K13611 - - 0.00000000000000000004875 91.0
PYH2_k127_6976821_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000003546 73.0
PYH2_k127_6976821_4 Glycosyltransferase like family 2 - - - 0.0000000000005217 79.0
PYH2_k127_7011531_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1002.0
PYH2_k127_7011531_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 385.0
PYH2_k127_7011531_2 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008431 268.0
PYH2_k127_7011531_3 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001992 239.0
PYH2_k127_7067724_0 DEAD DEAH box helicase K06877 - - 0.0 1185.0
PYH2_k127_7067724_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 602.0
PYH2_k127_7067724_2 Exonuclease K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
PYH2_k127_7067724_3 - - - - 0.0000000000000000000000000000000000000000001995 162.0
PYH2_k127_7067724_4 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000000026 115.0
PYH2_k127_7076664_0 acid binding OB-fold tRNA helicase-type K07463 - - 1.399e-252 782.0
PYH2_k127_7076664_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000004089 171.0
PYH2_k127_7076664_2 - - - - 0.00000000000000000000000000000000000000000003552 161.0
PYH2_k127_7076664_3 - - - - 0.00000000000000000000001014 103.0
PYH2_k127_7076664_4 - - - - 0.000000000000000000006974 96.0
PYH2_k127_7093892_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 7.986e-267 828.0
PYH2_k127_7093892_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 2.074e-237 737.0
PYH2_k127_7093892_10 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000000000001641 109.0
PYH2_k127_7093892_11 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000000000009663 97.0
PYH2_k127_7093892_2 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 438.0
PYH2_k127_7093892_3 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 366.0
PYH2_k127_7093892_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000001035 246.0
PYH2_k127_7093892_5 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000000000000000000000000000000000000376 219.0
PYH2_k127_7093892_6 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000000000000000000000000000006949 181.0
PYH2_k127_7093892_7 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000001231 160.0
PYH2_k127_7093892_8 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000000000000000007366 150.0
PYH2_k127_7093892_9 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000000000000000815 114.0
PYH2_k127_7098374_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.139e-242 756.0
PYH2_k127_7098374_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000246 274.0
PYH2_k127_7098374_2 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000001028 183.0
PYH2_k127_7098374_3 - - - - 0.000000000000000000000000000000000005137 138.0
PYH2_k127_7098374_4 Protein of unknown function (DUF2551) - - - 0.000000000000000001024 85.0
PYH2_k127_7115322_0 Belongs to the UPF0288 family - - - 1.589e-225 709.0
PYH2_k127_7115322_1 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005699 245.0
PYH2_k127_7115322_2 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.00000000000000000000000000000000000000003749 152.0
PYH2_k127_7117302_0 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 326.0
PYH2_k127_7117302_1 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 304.0
PYH2_k127_7117302_2 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 283.0
PYH2_k127_7117302_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004312 273.0
PYH2_k127_7117302_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000011 164.0
PYH2_k127_7121064_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.137e-275 856.0
PYH2_k127_7121064_1 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 610.0
PYH2_k127_7121064_2 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 479.0
PYH2_k127_7121064_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000009257 204.0
PYH2_k127_7158346_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1063.0
PYH2_k127_7158346_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 1.873e-228 713.0
PYH2_k127_7158346_2 Belongs to the TCP-1 chaperonin family K22447 - - 7.238e-204 640.0
PYH2_k127_7158346_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 398.0
PYH2_k127_7158346_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 335.0
PYH2_k127_7158346_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000002772 237.0
PYH2_k127_7158346_6 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000000000000000000000000001339 209.0
PYH2_k127_7158346_7 SigmaK-factor processing regulatory protein BofA K06317 - - 0.000000000000000000000002166 104.0
PYH2_k127_7158346_8 - - - - 0.000000000000000001267 85.0
PYH2_k127_7175738_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.073e-230 737.0
PYH2_k127_7175738_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 526.0
PYH2_k127_7175738_2 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 349.0
PYH2_k127_7175738_3 LUD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004248 238.0
PYH2_k127_7175738_4 Rieske [2Fe-2S] domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005783,GO:0005829,GO:0006915,GO:0008150,GO:0008219,GO:0009987,GO:0012501,GO:0012505,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0097194 - 0.000000000000000003782 87.0
PYH2_k127_7175738_5 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.0000000000531 63.0
PYH2_k127_7175738_6 Protein of unknown function (DUF1059) - - - 0.0009014 46.0
PYH2_k127_720459_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 1.483e-227 711.0
PYH2_k127_720459_1 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000008042 185.0
PYH2_k127_720459_2 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000000002686 180.0
PYH2_k127_720459_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000002274 155.0
PYH2_k127_720459_4 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000001112 98.0
PYH2_k127_729462_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 1.142e-235 732.0
PYH2_k127_729462_1 Hydrogenase maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.0000000000000000000004136 98.0
PYH2_k127_7303606_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.0000000000000000000000000000000000000000000000000000000000000000001546 244.0
PYH2_k127_7429966_0 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 542.0
PYH2_k127_7429966_1 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 453.0
PYH2_k127_7429966_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 378.0
PYH2_k127_7429966_3 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000002566 247.0
PYH2_k127_7429966_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000385 231.0
PYH2_k127_7429966_5 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000000000000000000000000007157 184.0
PYH2_k127_7429966_6 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000003218 138.0
PYH2_k127_7455774_0 Belongs to the MCM family K10726 - - 0.0 1200.0
PYH2_k127_7455774_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 496.0
PYH2_k127_7455774_2 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 482.0
PYH2_k127_7455774_3 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 437.0
PYH2_k127_7455774_4 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 387.0
PYH2_k127_7455774_5 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000001053 270.0
PYH2_k127_7455774_6 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000000000000000000001209 143.0
PYH2_k127_7455774_7 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000001573 138.0
PYH2_k127_7468136_0 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 605.0
PYH2_k127_7468136_1 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 321.0
PYH2_k127_7468136_2 zinc finger, SWIM - - - 0.0000000000000000000000000000000000000006323 150.0
PYH2_k127_7470028_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1095.0
PYH2_k127_7470028_1 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 316.0
PYH2_k127_7470028_2 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000007086 149.0
PYH2_k127_7509272_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 581.0
PYH2_k127_7509272_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 477.0
PYH2_k127_7509272_2 - - - - 0.0000000000000000000000000000000000000000000000000001086 186.0
PYH2_k127_7513883_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000001883 196.0
PYH2_k127_7513883_1 Viral (Superfamily 1) RNA helicase K03581 - 3.1.11.5 0.0000000000000000000000001827 106.0
PYH2_k127_7571094_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1131.0
PYH2_k127_7571094_1 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 601.0
PYH2_k127_7598425_0 Chemotaxis protein CheY K02479 - - 0.00000000000000000000000000000000000000000000000000007921 193.0
PYH2_k127_7598425_1 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 0.00000000000000000000002932 107.0
PYH2_k127_7601260_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
PYH2_k127_7601260_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 476.0
PYH2_k127_7601260_2 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 377.0
PYH2_k127_7601260_3 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004267 242.0
PYH2_k127_7601260_4 metal-binding protein - - - 0.0000000000000000000000000000000000007334 140.0
PYH2_k127_7602924_0 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.00000000000000000000000000000000000000000000000000000003426 205.0
PYH2_k127_7602924_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000003004 187.0
PYH2_k127_7602924_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000001896 158.0
PYH2_k127_7602924_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000001839 84.0
PYH2_k127_7621953_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1324.0
PYH2_k127_7621953_1 PFAM Major Facilitator Superfamily - - - 0.00000000002646 71.0
PYH2_k127_7714078_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001235 279.0
PYH2_k127_7714078_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004826 261.0
PYH2_k127_7714078_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000002396 216.0
PYH2_k127_773777_0 Roadblock LC7 - - - 0.000000007515 61.0
PYH2_k127_7745024_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 419.0
PYH2_k127_7745024_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 383.0
PYH2_k127_7745024_10 Ribonuclease III family - - - 0.00000000000002141 79.0
PYH2_k127_7745024_2 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 380.0
PYH2_k127_7745024_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 357.0
PYH2_k127_7745024_4 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 318.0
PYH2_k127_7745024_5 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001638 272.0
PYH2_k127_7745024_6 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
PYH2_k127_7745024_7 - - - - 0.0000000000000000000000000000000000000000000000000000005308 198.0
PYH2_k127_7745024_8 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000000001218 179.0
PYH2_k127_7745024_9 Pas domain - - - 0.00000000000000000000000000000000000000009954 159.0
PYH2_k127_7748490_0 WD-40 repeat-containing protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 322.0
PYH2_k127_7760092_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 1.072e-208 652.0
PYH2_k127_7760092_1 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 577.0
PYH2_k127_7760092_2 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 544.0
PYH2_k127_7760092_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 515.0
PYH2_k127_7760092_4 Belongs to the UPF0285 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 455.0
PYH2_k127_7760092_5 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
PYH2_k127_7760092_6 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 301.0
PYH2_k127_7760092_7 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000000000000006826 154.0
PYH2_k127_7779861_0 AN1-like Zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000004788 237.0
PYH2_k127_7779861_1 META domain - - - 0.00000000000000000000000000000003387 128.0
PYH2_k127_7779861_2 Dodecin K09165 - - 0.0000000000007236 71.0
PYH2_k127_782547_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 304.0
PYH2_k127_782547_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006694 259.0
PYH2_k127_782547_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001362 250.0
PYH2_k127_782547_3 - - - - 0.0000000000000000000000000000000003979 145.0
PYH2_k127_7882626_0 Alpha/beta hydrolase family - - - 0.000000000000000000001543 100.0
PYH2_k127_7882626_1 carboxylic ester hydrolase activity - - - 0.00000000000000195 84.0
PYH2_k127_7884454_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 474.0
PYH2_k127_7884454_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 405.0
PYH2_k127_7884454_2 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 389.0
PYH2_k127_7884454_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 370.0
PYH2_k127_7884454_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 325.0
PYH2_k127_7884454_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 324.0
PYH2_k127_7884454_6 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 299.0
PYH2_k127_7884454_7 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 296.0
PYH2_k127_7884454_8 Zn-ribbon containing protein K07163 - - 0.00000000000000000000000000000000000000000000000000000000000005827 215.0
PYH2_k127_7938024_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.727e-313 966.0
PYH2_k127_7938024_1 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 451.0
PYH2_k127_7938024_2 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.000000000000000000000000000000000000000005605 157.0
PYH2_k127_7938024_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000004175 119.0
PYH2_k127_7938024_4 - - - - 0.00000000000000008191 88.0
PYH2_k127_7962901_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 1.056e-194 609.0
PYH2_k127_7962901_1 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 509.0
PYH2_k127_7962901_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 423.0
PYH2_k127_7962901_3 PFAM sigma-70 region 4 domain protein K09714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 248.0
PYH2_k127_7962901_4 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.00000000000000000000000000000000001659 136.0
PYH2_k127_7978011_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 529.0
PYH2_k127_7978011_1 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
PYH2_k127_7978011_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 305.0
PYH2_k127_7978011_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000001679 90.0
PYH2_k127_7992521_0 TGS domain protein K06942 - - 3.085e-214 670.0
PYH2_k127_7992521_1 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 306.0
PYH2_k127_7992521_2 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000006088 173.0
PYH2_k127_79947_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 572.0
PYH2_k127_79947_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 397.0
PYH2_k127_79947_2 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
PYH2_k127_79947_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007,K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000209 145.0
PYH2_k127_79947_4 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000001105 77.0
PYH2_k127_8166627_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 558.0
PYH2_k127_8166627_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 404.0
PYH2_k127_8166627_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 353.0
PYH2_k127_8166627_3 hydrolase K04794 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000005376 207.0
PYH2_k127_8166627_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000001658 79.0
PYH2_k127_8191914_0 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 573.0
PYH2_k127_8191914_1 methanogen marker protein 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 297.0
PYH2_k127_8191914_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000595 251.0
PYH2_k127_8191914_3 transcription factor (CBF NF-Y) - - - 0.000000000000000000000000000001375 123.0
PYH2_k127_8205518_0 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 2.542e-227 709.0
PYH2_k127_8205518_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000001995 201.0
PYH2_k127_8205518_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
PYH2_k127_8230844_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 347.0
PYH2_k127_8230844_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 289.0
PYH2_k127_8230844_2 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002952 250.0
PYH2_k127_8230844_3 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000002361 111.0
PYH2_k127_8230844_4 Protein of unknown function (DUF2769) - - - 0.00000000000000002466 84.0
PYH2_k127_8258490_0 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 574.0
PYH2_k127_8258490_1 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 297.0
PYH2_k127_8263817_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 330.0
PYH2_k127_8328846_0 Replication factor C K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 396.0
PYH2_k127_8328846_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 313.0
PYH2_k127_8328846_2 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000001288 221.0
PYH2_k127_8346690_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 583.0
PYH2_k127_8346690_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000004014 228.0
PYH2_k127_8366601_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 4.8e-254 786.0
PYH2_k127_8366601_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 515.0
PYH2_k127_8366601_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000009682 91.0
PYH2_k127_8366601_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 354.0
PYH2_k127_8366601_3 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 298.0
PYH2_k127_8366601_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000000000000000000000005737 224.0
PYH2_k127_8366601_5 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000000000000000000002441 218.0
PYH2_k127_8366601_6 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000000000000000000000000000005761 176.0
PYH2_k127_8366601_7 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000000000000000000000000000000000000106 168.0
PYH2_k127_8366601_8 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000001001 109.0
PYH2_k127_8366601_9 PFAM Ribosomal LX protein K02944 - - 0.0000000000000000000000008116 105.0
PYH2_k127_8389219_0 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 474.0
PYH2_k127_8389219_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 398.0
PYH2_k127_8389219_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 366.0
PYH2_k127_8455787_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 487.0
PYH2_k127_8455787_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 317.0
PYH2_k127_8455787_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000168 216.0
PYH2_k127_8455787_3 - - - - 0.000000000000000000000000000000000000000000000007582 179.0
PYH2_k127_8455787_4 - - - - 0.0000000000000128 73.0
PYH2_k127_8466616_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1238.0
PYH2_k127_8466616_1 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 542.0
PYH2_k127_8466616_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 312.0
PYH2_k127_8466616_3 PFAM metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 291.0
PYH2_k127_8466616_4 Large-conductance mechanosensitive channel, MscL K03282 - - 0.00000000000000000000000000000000000003555 146.0
PYH2_k127_8466616_5 TIR domain - - - 0.00000000000000000000000000025 119.0
PYH2_k127_8553293_0 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 381.0
PYH2_k127_8553293_1 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000005132 236.0
PYH2_k127_8553293_2 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000005501 210.0
PYH2_k127_8553293_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000131 175.0
PYH2_k127_8553815_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 2.153e-238 743.0
PYH2_k127_8553815_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000002054 133.0
PYH2_k127_8553815_2 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.0000000000000000002448 89.0
PYH2_k127_8553815_3 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000002342 68.0
PYH2_k127_8553815_4 - K05570 - - 0.000001833 53.0
PYH2_k127_8581665_0 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 590.0
PYH2_k127_8581665_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000009015 131.0
PYH2_k127_8581665_2 TIGRFAM acetate--CoA ligase K01895 - 6.2.1.1 0.000003476 48.0
PYH2_k127_8596642_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 3.893e-291 910.0
PYH2_k127_8600628_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 314.0
PYH2_k127_8600628_1 - - - - 0.0000000000000000003612 88.0
PYH2_k127_8652895_0 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 293.0
PYH2_k127_8652895_1 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006657 273.0
PYH2_k127_8652895_2 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000232 189.0
PYH2_k127_8655312_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 318.0
PYH2_k127_8655312_1 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000001035 144.0
PYH2_k127_8658940_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.43e-208 661.0
PYH2_k127_8658940_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000002112 213.0
PYH2_k127_8658940_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000001602 189.0
PYH2_k127_8658940_3 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000005464 55.0
PYH2_k127_8695009_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 549.0
PYH2_k127_8695009_1 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
PYH2_k127_8695009_2 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 373.0
PYH2_k127_8695009_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 312.0
PYH2_k127_8695009_4 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000001337 163.0
PYH2_k127_8695009_5 Uracil DNA glycosylase superfamily K03649 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097507,GO:0140097,GO:1901360 3.2.2.28 0.00000000000000000000000000000000000000000003719 165.0
PYH2_k127_8695009_6 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.000000000000000000000000000000003525 129.0
PYH2_k127_8700897_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 1.502e-226 705.0
PYH2_k127_8700897_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 334.0
PYH2_k127_8700897_2 transcription termination protein NusA K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000436 275.0
PYH2_k127_8700897_3 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.00000000000000000000000000000000000000000000000001072 181.0
PYH2_k127_8700897_4 metallopeptidase activity - - - 0.000000000000000001406 99.0
PYH2_k127_8700897_5 - - - - 0.00000000002155 76.0
PYH2_k127_8701174_0 Protein-export membrane protein SecD K03072 - - 4.197e-227 713.0
PYH2_k127_8701174_1 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 394.0
PYH2_k127_8701174_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 328.0
PYH2_k127_8701174_3 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000001175 247.0
PYH2_k127_8701174_4 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000004989 182.0
PYH2_k127_8701174_5 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000004063 172.0
PYH2_k127_8701174_6 Protein of unknown function (DUF2551) - - - 0.00000000000000000000001888 100.0
PYH2_k127_8766801_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000004512 65.0
PYH2_k127_8766801_1 polysaccharide biosynthetic process - - - 0.0000001741 63.0
PYH2_k127_8779984_0 Involved in regulation of DNA replication K10725 - - 1.334e-257 797.0
PYH2_k127_8779984_1 PFAM Aminotransferase class I and II K10907 - - 8.863e-202 632.0
PYH2_k127_8779984_2 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 285.0
PYH2_k127_8779984_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004224 278.0
PYH2_k127_8863243_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1287.0
PYH2_k127_8863243_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 516.0
PYH2_k127_8863243_10 - - - - 0.000000000000005339 76.0
PYH2_k127_8863243_2 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 471.0
PYH2_k127_8863243_3 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 455.0
PYH2_k127_8863243_4 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 391.0
PYH2_k127_8863243_5 Alpha beta hydrolase K01066,K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 358.0
PYH2_k127_8863243_6 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 282.0
PYH2_k127_8863243_7 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000000002664 201.0
PYH2_k127_8863243_8 - - - - 0.000000000000000000000000000000000000000002395 163.0
PYH2_k127_8863243_9 - - - - 0.000000000000000000000000000000000000000007324 158.0
PYH2_k127_9013630_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.758e-214 673.0
PYH2_k127_9013630_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001291 274.0
PYH2_k127_9013630_2 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
PYH2_k127_9013630_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000001876 224.0
PYH2_k127_9013630_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000003487 212.0
PYH2_k127_9013630_5 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000002807 168.0
PYH2_k127_9044625_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 411.0
PYH2_k127_9044625_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 411.0
PYH2_k127_9044625_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000000000000000000000000000002964 177.0
PYH2_k127_9044625_3 PFAM PUA domain K07398 - - 0.0000000000000000001618 95.0
PYH2_k127_9095778_0 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 415.0
PYH2_k127_9095778_1 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 384.0
PYH2_k127_9095778_2 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 318.0
PYH2_k127_9217269_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 532.0
PYH2_k127_9217269_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 507.0
PYH2_k127_9217269_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 387.0
PYH2_k127_9217269_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 357.0
PYH2_k127_9217269_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
PYH2_k127_9217269_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000001547 213.0
PYH2_k127_9217269_6 Belongs to the UPF0434 family - - - 0.00000000000000001217 84.0
PYH2_k127_9217269_7 - - - - 0.0000000000000000421 89.0
PYH2_k127_9217269_8 - - - - 0.0000000001376 68.0
PYH2_k127_9223905_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 322.0
PYH2_k127_9223905_1 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000000001409 184.0
PYH2_k127_9223905_2 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000000001188 172.0
PYH2_k127_9223905_3 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000000000000001656 153.0
PYH2_k127_9269110_0 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
PYH2_k127_9269110_1 COG2226 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000007446 179.0
PYH2_k127_9280204_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1397.0
PYH2_k127_9280204_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 3.165e-237 737.0
PYH2_k127_9280204_10 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.0000000000000000000000008925 108.0
PYH2_k127_9280204_11 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.0001125 48.0
PYH2_k127_9280204_2 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 549.0
PYH2_k127_9280204_3 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 459.0
PYH2_k127_9280204_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 371.0
PYH2_k127_9280204_5 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 323.0
PYH2_k127_9280204_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000253 227.0
PYH2_k127_9280204_7 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000004594 184.0
PYH2_k127_9280204_8 4-Hydroxyphenylpyruvate dioxygenase - - - 0.0000000000000000000000000000000000000000003359 160.0
PYH2_k127_9280204_9 PAS domain - - - 0.000000000000000000000000000007873 120.0
PYH2_k127_9293461_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0 1035.0
PYH2_k127_9293461_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 4.207e-205 642.0
PYH2_k127_9293461_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000003854 143.0
PYH2_k127_952228_0 SMART Elongator protein 3 MiaB NifB - - - 5.24e-296 919.0
PYH2_k127_952228_1 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000000000000000000000000000000001118 237.0